bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
164,496 sequences; 82,071,388 total letters
Query= Eten_8241_orf1
Length=109
Score E
Sequences producing significant alignments: (Bits) Value
pfa:PFI0920c dihydrouridine synthase, putative; K05539 tRNA-di... 149 3e-36
tgo:TGME49_066880 dihydrouridine synthase domain-containing pr... 135 4e-32
tpv:TP01_0028 tRNA-dihydrouridine synthase A; K05539 tRNA-dihy... 103 2e-22
eco:b4049 dusA, ECK4041, JW5950, yjbN; tRNA-dihydrouridine syn... 102 2e-22
ath:AT3G63510 FAD binding / catalytic/ tRNA dihydrouridine syn... 101 6e-22
bbo:BBOV_I002610 19.m02130; dihydrouridine synthase (Dus) doma... 99.0 3e-21
cpv:cgd2_3570 YjbN-like Dus1p tRNA dihydouriding synthase Tim ... 92.0 4e-19
ath:AT5G47970 nitrogen regulation family protein; K05539 tRNA-... 87.0 1e-17
eco:b3260 dusB, ECK3247, JW3228, yhdG; tRNA-dihydrouridine syn... 53.1 2e-07
ath:AT5G67220 nitrogen regulation family protein; K05545 tRNA-... 51.2 8e-07
sce:YML080W DUS1; Dihydrouridine synthase, member of a widespr... 50.8 1e-06
ath:AT3G49640 FAD binding / catalytic/ tRNA dihydrouridine syn... 50.1 2e-06
tgo:TGME49_080780 dihydrouridine synthase domain-containing pr... 50.1 2e-06
pfa:PF14_0086 tRNA-dihydrouridine synthase, putative; K05545 t... 47.8 1e-05
hsa:56931 DUS3L, DUS3, FLJ13896; dihydrouridine synthase 3-lik... 47.4 1e-05
eco:b2140 dusC, ECK2133, JW2128, yohI; tRNA-dihydrouridine syn... 47.4 1e-05
bbo:BBOV_IV004780 23.m05837; dihydrouridine synthase; K05542 t... 46.6 2e-05
tgo:TGME49_002790 dihydrouridine synthase domain-containing pr... 46.2 3e-05
cel:Y54E5A.6 hypothetical protein; K05543 tRNA-dihydrouridine ... 45.1 5e-05
cel:C45G9.2 hypothetical protein; K05545 tRNA-dihydrouridine s... 43.9 1e-04
dre:445096 dus4l, zgc:92033; dihydrouridine synthase 4-like (S... 43.9 1e-04
dre:100003049 dus2l; dihydrouridine synthase 2-like, SMM1 homo... 42.7 3e-04
xla:379349 dus3l, MGC53781; dihydrouridine synthase 3-like; K0... 42.4 3e-04
hsa:54920 DUS2L, DUS2, FLJ20399, SMM1, URLC8; dihydrouridine s... 42.4 4e-04
mmu:68730 Dus1l, 1110032N12Rik; dihydrouridine synthase 1-like... 42.4 4e-04
cel:F36A2.2 hypothetical protein; K05542 tRNA-dihydrouridine s... 42.0 4e-04
ath:AT4G38890 dihydrouridine synthase family protein; K05544 t... 42.0 5e-04
mmu:66369 Dus2l, 2310016K04Rik; dihydrouridine synthase 2-like... 41.6 6e-04
mmu:224907 Dus3l, AI662135, AW557805, MGC56820; dihydrouridine... 41.6 7e-04
xla:446385 dus1l, MGC83715; dihydrouridine synthase 1-like; K0... 40.4 0.001
xla:432319 MGC132093; hypothetical protein MGC78973; K05542 tR... 40.4 0.002
xla:734320 dus4l; dihydrouridine synthase 4-like; K05545 tRNA-... 40.0 0.002
sce:YNR015W SMM1, DUS2; Dihydrouridine synthase, member of a f... 39.7 0.002
hsa:64118 DUS1L, DUS1, PP3111; dihydrouridine synthase 1-like ... 39.3 0.003
dre:393647 MGC63779; zgc:63779; K05544 tRNA-dihydrouridine syn... 39.3 0.003
tgo:TGME49_072570 hypothetical protein 38.5 0.006
mmu:71916 Dus4l, 2310069P03Rik, 2700089B10Rik, AI482040, MGC13... 38.1 0.008
dre:322715 dus1l, wu:fb71f06, zgc:63748; dihydrouridine syntha... 37.4 0.013
dre:100330185 dihydrouridine synthase 1-like (S. cerevisiae)-l... 37.0 0.014
hsa:11062 DUS4L, DUS4, MGC133233, PP35; dihydrouridine synthas... 36.6 0.018
tgo:TGME49_028080 hypothetical protein ; K05544 tRNA-dihydrour... 35.8 0.036
sce:YLR401C DUS3; Dihydrouridine synthase, member of a widespr... 35.4 0.042
cel:Y37E11B.5 hypothetical protein; K05544 tRNA-dihydrouridine... 34.7 0.074
hsa:1806 DPYD, DHP, DHPDHASE, DPD, MGC132008, MGC70799; dihydr... 33.5 0.17
mmu:99586 Dpyd, AI315208, DPD, E330028L06Rik, MGC37940; dihydr... 32.7 0.32
cel:C25F6.3 dpyd-1; DihydroPYrimidine Dehydrogenase family mem... 32.3 0.41
xla:447312 dpyd, MGC81821, dhp, dhpdhase, dpd; dihydropyrimidi... 32.0 0.55
eco:b2147 yeiA, dpdB, ECK2140, JW2134; dihydropyrimidine dehyd... 31.2 0.84
dre:556707 hypothetical LOC556707 30.8 1.0
dre:405829 dpyd, MGC77205, zgc:77205; dihydropyrimidine dehydr... 30.8 1.1
> pfa:PFI0920c dihydrouridine synthase, putative; K05539 tRNA-dihydrouridine
synthase A [EC:1.-.-.-]
Length=577
Score = 149 bits (375), Expect = 3e-36, Method: Composition-based stats.
Identities = 65/102 (63%), Positives = 85/102 (83%), Gaps = 0/102 (0%)
Query 8 LGFDDVEHPIVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMR 67
LGFD+ EHPIVCQLGG + +++EAA E AGYDE+N+NVGCPS +V +KG+FGA+LM+
Sbjct 247 LGFDNNEHPIVCQLGGCDMNSMSEAAILVEQAGYDEININVGCPSTKVANKGAFGASLMK 306
Query 68 SPTKVRDIVYEMKRRVQIPVTVKCRLGVDNLDSPEFTKQFVE 109
+P +VR+IVYE+K++VQIPVTVK R GVDN DS +F K F+E
Sbjct 307 NPEQVRNIVYEIKKKVQIPVTVKIRTGVDNYDSFDFLKTFIE 348
> tgo:TGME49_066880 dihydrouridine synthase domain-containing
protein (EC:1.3.1.2); K05539 tRNA-dihydrouridine synthase A
[EC:1.-.-.-]
Length=394
Score = 135 bits (340), Expect = 4e-32, Method: Compositional matrix adjust.
Identities = 62/104 (59%), Positives = 80/104 (76%), Gaps = 0/104 (0%)
Query 6 HTLGFDDVEHPIVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAAL 65
L +D+EHPIVCQLGGS+P+ +AEA E G+DE+NLNVGCPS RVV +G FGAAL
Sbjct 60 QNLCLEDIEHPIVCQLGGSDPKTLAEAGKLIEKLGFDEINLNVGCPSNRVVSQGCFGAAL 119
Query 66 MRSPTKVRDIVYEMKRRVQIPVTVKCRLGVDNLDSPEFTKQFVE 109
M++P VRDIV+E++R VQIPVTVK R+G D+ DS + + FV+
Sbjct 120 MKTPETVRDIVHEIRRHVQIPVTVKTRIGYDHCDSRDVLRNFVQ 163
> tpv:TP01_0028 tRNA-dihydrouridine synthase A; K05539 tRNA-dihydrouridine
synthase A [EC:1.-.-.-]
Length=471
Score = 103 bits (256), Expect = 2e-22, Method: Composition-based stats.
Identities = 56/123 (45%), Positives = 70/123 (56%), Gaps = 22/123 (17%)
Query 8 LGFDDVEHPIVCQLG----------GSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVD 57
L F++ EHPIV QLG G+ P+ + EA + GYDE+NLN GCPS RV
Sbjct 144 LKFEENEHPIVAQLGIFYQHKIVPGGNCPETLVEAGRILKKFGYDEINLNAGCPSPRVSG 203
Query 58 KG------------SFGAALMRSPTKVRDIVYEMKRRVQIPVTVKCRLGVDNLDSPEFTK 105
KG FGA+LM+ VRDI + M R +++PVTVK RLGVD DS EF +
Sbjct 204 KGIYKFMLKLFNLGCFGASLMKEKELVRDIAHHMLRELEMPVTVKTRLGVDEFDSYEFVR 263
Query 106 QFV 108
FV
Sbjct 264 DFV 266
> eco:b4049 dusA, ECK4041, JW5950, yjbN; tRNA-dihydrouridine synthase
A; K05539 tRNA-dihydrouridine synthase A [EC:1.-.-.-]
Length=330
Score = 102 bits (255), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 53/101 (52%), Positives = 66/101 (65%), Gaps = 1/101 (0%)
Query 8 LGFDDVEHPIVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMR 67
L + + EHP+ QLGGS+P +A+ A AE GYDE+NLNVGCPS R V G FGA LM
Sbjct 57 LAYSEEEHPVALQLGGSDPAALAQCAKLAEARGYDEINLNVGCPSDR-VQNGMFGACLMG 115
Query 68 SPTKVRDIVYEMKRRVQIPVTVKCRLGVDNLDSPEFTKQFV 108
+ V D V M+ V IPVTVK R+G+D+ DS EF F+
Sbjct 116 NAQLVADCVKAMRDVVSIPVTVKTRIGIDDQDSYEFLCDFI 156
> ath:AT3G63510 FAD binding / catalytic/ tRNA dihydrouridine synthase
Length=386
Score = 101 bits (251), Expect = 6e-22, Method: Compositional matrix adjust.
Identities = 49/101 (48%), Positives = 65/101 (64%), Gaps = 0/101 (0%)
Query 8 LGFDDVEHPIVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMR 67
L F +HPIV QLGGSN +N+A+AA ++ GYDE+NLN GCPS +V G FG +LM
Sbjct 68 LAFSPQQHPIVLQLGGSNVENLAKAAKLSDAYGYDEINLNCGCPSPKVAGHGCFGVSLML 127
Query 68 SPTKVRDIVYEMKRRVQIPVTVKCRLGVDNLDSPEFTKQFV 108
P V + + + +PVTVKCR+GVDN DS + F+
Sbjct 128 KPKLVGEAMSAIAANTNVPVTVKCRIGVDNHDSYDELCDFI 168
> bbo:BBOV_I002610 19.m02130; dihydrouridine synthase (Dus) domain
containing protein; K05539 tRNA-dihydrouridine synthase
A [EC:1.-.-.-]
Length=362
Score = 99.0 bits (245), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 52/98 (53%), Positives = 63/98 (64%), Gaps = 0/98 (0%)
Query 11 DDVEHPIVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPT 70
D EHPIV QLGG+N ++++A A GY E NLNVGCPS RV KG FGAALM
Sbjct 69 DANEHPIVLQLGGNNLDSLSKAGNIALGYGYTEFNLNVGCPSTRVSGKGCFGAALMNDAP 128
Query 71 KVRDIVYEMKRRVQIPVTVKCRLGVDNLDSPEFTKQFV 108
V IV ++ + PVTVK RLGVD+ DS EF + F+
Sbjct 129 LVGRIVKHLRSELGTPVTVKHRLGVDHNDSYEFVRDFI 166
> cpv:cgd2_3570 YjbN-like Dus1p tRNA dihydouriding synthase Tim
barrel ; K05539 tRNA-dihydrouridine synthase A [EC:1.-.-.-]
Length=519
Score = 92.0 bits (227), Expect = 4e-19, Method: Composition-based stats.
Identities = 44/104 (42%), Positives = 65/104 (62%), Gaps = 6/104 (5%)
Query 11 DDVEHPIVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPT 70
+D+E+P+V QLGG+NPQ + +A A G+ NLNVGCPSC+V KGSFGA+L ++P
Sbjct 85 NDIENPLVLQLGGNNPQKMEKAIEIAYKYGFQNFNLNVGCPSCKVASKGSFGASLFKNPL 144
Query 71 KVRDIVYEMKRR------VQIPVTVKCRLGVDNLDSPEFTKQFV 108
+V IV ++ V ++VK R+GVD D+ + F+
Sbjct 145 RVAKIVDTCNKKLIHLGLVNKRISVKTRIGVDQYDTYQHLYNFI 188
> ath:AT5G47970 nitrogen regulation family protein; K05539 tRNA-dihydrouridine
synthase A [EC:1.-.-.-]
Length=387
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 43/93 (46%), Positives = 56/93 (60%), Gaps = 0/93 (0%)
Query 8 LGFDDVEHPIVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMR 67
L F +HPIV Q+GG N +N+A+A A YDE+N N GCPS +V +G FGA LM
Sbjct 59 LAFSPDQHPIVLQIGGRNLENLAKATRLANAYAYDEINFNCGCPSPKVSGRGCFGALLML 118
Query 68 SPTKVRDIVYEMKRRVQIPVTVKCRLGVDNLDS 100
P V + + + VTVKCR+GVD+ DS
Sbjct 119 DPKFVGEAMSVIAANTNAAVTVKCRIGVDDHDS 151
> eco:b3260 dusB, ECK3247, JW3228, yhdG; tRNA-dihydrouridine synthase
B; K05540 tRNA-dihydrouridine synthase B [EC:1.-.-.-]
Length=321
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 27/75 (36%), Positives = 49/75 (65%), Gaps = 1/75 (1%)
Query 20 QLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVRDIVYEM 79
Q+ GS+P+ +A+AA +G +++N+GCP+ + V++ G+AL++ P V+ I+ E+
Sbjct 70 QIAGSDPKEMADAARINVESGAQIIDINMGCPA-KKVNRKLAGSALLQYPDVVKSILTEV 128
Query 80 KRRVQIPVTVKCRLG 94
V +PVT+K R G
Sbjct 129 VNAVDVPVTLKIRTG 143
> ath:AT5G67220 nitrogen regulation family protein; K05545 tRNA-dihydrouridine
synthase 4 [EC:1.-.-.-]
Length=423
Score = 51.2 bits (121), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 29/106 (27%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Query 2 QYRTHTLGFDDVEHPIVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSF 61
+YR + P+ Q ++P + EAA E D V++N+GCP R+ +G++
Sbjct 130 KYRNQEFTTCKEDRPLFVQFCANDPDTLLEAAKRVE-PYCDYVDINLGCPQ-RIARRGNY 187
Query 62 GAALMRSPTKVRDIVYEMKRRVQIPVTVKCRLGVDNLDSPEFTKQF 107
GA LM + V+ +V ++ + + +PV+ K R+ + D+ ++ K
Sbjct 188 GAFLMDNLPLVKSLVEKLAQNLNVPVSCKIRIFPNLEDTLKYAKML 233
> sce:YML080W DUS1; Dihydrouridine synthase, member of a widespread
family of conserved proteins including Smm1p, Dus3p, and
Dus4p; modifies pre-tRNA(Phe) at U17 (EC:1.-.-.-); K05542
tRNA-dihydrouridine synthase 1 [EC:1.-.-.-]
Length=423
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 29/103 (28%), Positives = 54/103 (52%), Gaps = 2/103 (1%)
Query 7 TLGFDDVEHPIVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALM 66
+L V+ P+V Q ++P+ + AA E D V+LN+GCP + KG +G+ LM
Sbjct 79 SLDGSSVDRPLVVQFCANDPEYLLAAAKLVE-DKCDAVDLNLGCPQG-IAKKGHYGSFLM 136
Query 67 RSPTKVRDIVYEMKRRVQIPVTVKCRLGVDNLDSPEFTKQFVE 109
+ +++ + + +++PVT K R+ D S + K ++
Sbjct 137 EEWDLIHNLINTLHKNLKVPVTAKIRIFDDCEKSLNYAKMVLD 179
> ath:AT3G49640 FAD binding / catalytic/ tRNA dihydrouridine synthase;
K05543 tRNA-dihydrouridine synthase 2 [EC:1.-.-.-]
Length=290
Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 30/99 (30%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Query 11 DDVEHPIVCQLGGSNPQNVAEAATWAELAGYD--EVNLNVGCPSCRVVDKGSFGAALMRS 68
D+ + +V Q+G S+ +A+ E+ D +++N+GCP + +G GAAL+
Sbjct 33 DEEKSRVVFQMGTSDAVRALKAS---EIVCNDVATIDINMGCPKAFSI-QGGMGAALLSK 88
Query 69 PTKVRDIVYEMKRRVQIPVTVKCRLGVDNLDSPEFTKQF 107
P + DI+ +KR + +PVT K RL D+ E ++
Sbjct 89 PELIHDILATLKRNLDVPVTCKIRLLKSPADTVELARRI 127
> tgo:TGME49_080780 dihydrouridine synthase domain-containing
protein ; K05543 tRNA-dihydrouridine synthase 2 [EC:1.-.-.-]
Length=653
Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 30/79 (37%), Positives = 45/79 (56%), Gaps = 6/79 (7%)
Query 17 IVCQLGGSNPQNVAEAATWAELAGYD--EVNLNVGCPSCRVVDKGSFGAALMRSPTKVRD 74
+V QLG S+ +AA L D V++N+GCP ++ G GAAL+++P D
Sbjct 327 VVMQLGTSDATRALKAAM---LVAQDVAAVDVNMGCPKSFSIN-GGMGAALLKTPLIATD 382
Query 75 IVYEMKRRVQIPVTVKCRL 93
I+ ++R + IPVT K RL
Sbjct 383 ILKTLRRNLDIPVTCKIRL 401
> pfa:PF14_0086 tRNA-dihydrouridine synthase, putative; K05545
tRNA-dihydrouridine synthase 4 [EC:1.-.-.-]
Length=340
Score = 47.8 bits (112), Expect = 1e-05, Method: Composition-based stats.
Identities = 26/96 (27%), Positives = 54/96 (56%), Gaps = 3/96 (3%)
Query 2 QYRTHTLGFDDVEHPIVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSF 61
+YR D++ P++ Q G++ + + EA + + + V++N+GCP ++ KG++
Sbjct 68 KYRKGYFKSCDMDKPVIAQFCGNDSKILLEAINFIK-DDVNAVDINLGCPQ-QIAKKGNY 125
Query 62 GAALMRSPTKVRDIVYEMKRRVQIPVTVKCRLGVDN 97
GA L+ +V +++ ++ IP+T K R +DN
Sbjct 126 GAFLLHKHDEVVNLISDITNNCVIPITCKIR-KIDN 160
> hsa:56931 DUS3L, DUS3, FLJ13896; dihydrouridine synthase 3-like
(S. cerevisiae); K05544 tRNA-dihydrouridine synthase 3 [EC:1.-.-.-]
Length=408
Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 31/77 (40%), Positives = 42/77 (54%), Gaps = 2/77 (2%)
Query 20 QLGGSNPQNVAEAA-TWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVRDIVYE 78
QL G+ P + + A + D V++NVGCP V KG G ALM TK + IV
Sbjct 123 QLEGAFPDTMTKCAELLSRTVEVDFVDINVGCPIDLVYKKGG-GCALMNRSTKFQQIVRG 181
Query 79 MKRRVQIPVTVKCRLGV 95
M + + +P+TVK R GV
Sbjct 182 MNQVLDVPLTVKIRTGV 198
> eco:b2140 dusC, ECK2133, JW2128, yohI; tRNA-dihydrouridine synthase
C; K05541 tRNA-dihydrouridine synthase C [EC:1.-.-.-]
Length=315
Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 32/80 (40%), Positives = 43/80 (53%), Gaps = 3/80 (3%)
Query 20 QLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVRDIVYEM 79
QL G PQ +AE A A G V+LN GCPS + V+ GA L++ P + M
Sbjct 68 QLLGQFPQWLAENAARAVELGSWGVDLNCGCPS-KTVNGSGGGATLLKDPELIYQGAKAM 126
Query 80 KRRV--QIPVTVKCRLGVDN 97
+ V +PV+VK RLG D+
Sbjct 127 REAVPAHLPVSVKVRLGWDS 146
> bbo:BBOV_IV004780 23.m05837; dihydrouridine synthase; K05542
tRNA-dihydrouridine synthase 1 [EC:1.-.-.-]
Length=355
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 4/92 (4%)
Query 2 QYRTHTLGFDDVEHPIVCQLGGSNPQNVAEAATWAELAGY-DEVNLNVGCPSCRVVDKGS 60
+YR D + P++ Q+ G + + +AA L G+ V+LN+GCP + G
Sbjct 54 KYRAVHFQTSDDDRPLIAQVCGDDAGTITQAARL--LKGHVSAVDLNLGCPQA-IAKDGH 110
Query 61 FGAALMRSPTKVRDIVYEMKRRVQIPVTVKCR 92
+G+ L+ P V IV + R V I VT K R
Sbjct 111 YGSFLLDEPDLVTGIVSRVTREVGIAVTCKIR 142
> tgo:TGME49_002790 dihydrouridine synthase domain-containing
protein (EC:5.1.3.9); K05542 tRNA-dihydrouridine synthase 1
[EC:1.-.-.-]
Length=540
Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
Query 12 DVEHPIVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPTK 71
+ + P+ Q G +P + AA E + V++N GCP + +G +GA L+ P
Sbjct 138 EFDEPVFVQFCGDSPATLLAAAQLVE-DEVEAVDVNFGCPQG-IARRGHYGAFLLNEPEL 195
Query 72 VRDIVYEMKRRVQIPVTVKCR 92
+ DIV + + ++ PVT K R
Sbjct 196 LVDIVSTLHKHLKTPVTCKMR 216
> cel:Y54E5A.6 hypothetical protein; K05543 tRNA-dihydrouridine
synthase 2 [EC:1.-.-.-]
Length=436
Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 31/94 (32%), Positives = 53/94 (56%), Gaps = 10/94 (10%)
Query 18 VCQLGGSNPQNVAEAATWAELAGYD--EVNLNVGCPSCRVVDKGSFGAALMRSPTKVRDI 75
+ Q+G ++ + +AA A++ G D +++N+GCP + G GAAL+ K+ DI
Sbjct 79 ILQIGTNSGE---KAAKIAQIVGDDVAGIDVNMGCPKPFSIHCG-MGAALLTQTEKIVDI 134
Query 76 VYEMKRRVQIPVTVKCRLGVDNLDSPEFTKQFVE 109
+ +K ++PVT K R+ LD PE T + V+
Sbjct 135 LTSLKSAAKVPVTCKIRV----LDDPEDTLKLVQ 164
> cel:C45G9.2 hypothetical protein; K05545 tRNA-dihydrouridine
synthase 4 [EC:1.-.-.-]
Length=284
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 30/96 (31%), Positives = 49/96 (51%), Gaps = 5/96 (5%)
Query 4 RTHTLGFDDVEHPIVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGA 63
R+ L + + P++ Q +P ++EAA V+LN GCP V KG FG+
Sbjct 38 RSSELSVCEGDSPLIVQFATDDPFVLSEAAEMVYKCSTG-VDLNCGCPKHDVRSKG-FGS 95
Query 64 ALMRSPTKVRDIVYEMKRRVQIP---VTVKCRLGVD 96
AL+ P + D+V + + R+ P V++K R+ D
Sbjct 96 ALLSKPELLADMVRQTRARIPDPDFSVSLKIRINHD 131
> dre:445096 dus4l, zgc:92033; dihydrouridine synthase 4-like
(S. cerevisiae); K05545 tRNA-dihydrouridine synthase 4 [EC:1.-.-.-]
Length=285
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 26/86 (30%), Positives = 46/86 (53%), Gaps = 5/86 (5%)
Query 14 EHPIVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVR 73
+ P++ Q + Q +A+AA D V+LN GCP + +G +GA L+ P V+
Sbjct 48 DRPLIVQFAAKDAQTLADAACVVSPFS-DGVDLNCGCPQRWAMSEG-YGACLINKPELVK 105
Query 74 DIVYEMKRRVQIP---VTVKCRLGVD 96
D+V ++ ++ P V++K R+ D
Sbjct 106 DMVRHVRNQIDNPNYAVSIKIRIHKD 131
> dre:100003049 dus2l; dihydrouridine synthase 2-like, SMM1 homolog
(S. cerevisiae); K05543 tRNA-dihydrouridine synthase 2
[EC:1.-.-.-]
Length=504
Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
Query 17 IVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVRDIV 76
+V Q+G ++P+ A E V++N+GCP KG G+AL+ P K+ I+
Sbjct 89 VVFQMGTADPERALAVAKLVE-NDVAAVDVNMGCPK-EYSTKGGMGSALLSDPEKIEAIL 146
Query 77 YEMKRRVQIPVTVKCRL 93
+ + + PVT K R+
Sbjct 147 TTLVKGISKPVTCKIRI 163
> xla:379349 dus3l, MGC53781; dihydrouridine synthase 3-like;
K05544 tRNA-dihydrouridine synthase 3 [EC:1.-.-.-]
Length=640
Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 29/77 (37%), Positives = 37/77 (48%), Gaps = 2/77 (2%)
Query 20 QLGGSNPQNVAEAATWAELA-GYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVRDIVYE 78
QL G+ P + + A D V++NVGCP V KG G LM K IV
Sbjct 355 QLEGAFPDTMTKCAELLNRTIDVDFVDINVGCPIDLVYKKGG-GCGLMNRTNKFEQIVKG 413
Query 79 MKRRVQIPVTVKCRLGV 95
M + +P+TVK R GV
Sbjct 414 MNSVLDVPLTVKIRTGV 430
> hsa:54920 DUS2L, DUS2, FLJ20399, SMM1, URLC8; dihydrouridine
synthase 2-like, SMM1 homolog (S. cerevisiae); K05543 tRNA-dihydrouridine
synthase 2 [EC:1.-.-.-]
Length=493
Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 27/79 (34%), Positives = 42/79 (53%), Gaps = 6/79 (7%)
Query 17 IVCQLGGSNPQNVAEAATWAE--LAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVRD 74
+V Q+G S+ + A E +AG D +N+GCP + KG GAAL+ P K+
Sbjct 84 VVFQMGTSDAERALAVARLVENDVAGID---VNMGCPK-QYSTKGGMGAALLSDPDKIEK 139
Query 75 IVYEMKRRVQIPVTVKCRL 93
I+ + + + PVT K R+
Sbjct 140 ILSTLVKGTRRPVTCKIRI 158
> mmu:68730 Dus1l, 1110032N12Rik; dihydrouridine synthase 1-like
(S. cerevisiae); K05542 tRNA-dihydrouridine synthase 1 [EC:1.-.-.-]
Length=475
Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 27/96 (28%), Positives = 49/96 (51%), Gaps = 6/96 (6%)
Query 1 SQYRTHTLGFD--DVEHPIVCQLGGSNPQNVAEAATWAELAGY-DEVNLNVGCPSCRVVD 57
+ YR L D + P++ Q ++P+ +AA A+ Y D ++LN+GCP +
Sbjct 58 ANYRKENLYCDVCPEDRPLIVQFCANDPEVFVQAALLAQ--DYCDAIDLNLGCPQ-MIAK 114
Query 58 KGSFGAALMRSPTKVRDIVYEMKRRVQIPVTVKCRL 93
+G +GA L ++ ++ R+ +PVT K R+
Sbjct 115 RGHYGAFLQEEWDLLQRMILLAHERLSVPVTCKIRV 150
> cel:F36A2.2 hypothetical protein; K05542 tRNA-dihydrouridine
synthase 1 [EC:1.-.-.-]
Length=527
Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 27/107 (25%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Query 3 YRTHTLGFDDVEHPIVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFG 62
YR ++L + P+V Q + A E D V+LN+GCP V +G +G
Sbjct 116 YRRNSLALVKADRPLVVQFCANKVDTFLAACRLVEDVC-DGVDLNLGCPQM-VAKRGRYG 173
Query 63 AALMRSPTKVRDIVYEMKRRVQIPVTVKCRLGVDNLDSPEFTKQFVE 109
+ L + ++V ++ ++P++ K R+ D + E+ K+ V+
Sbjct 174 SWLQDEVDLICEMVSAVRDYCRLPISCKIRVRDDRQQTVEYAKRLVD 220
> ath:AT4G38890 dihydrouridine synthase family protein; K05544
tRNA-dihydrouridine synthase 3 [EC:1.-.-.-]
Length=700
Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 28/86 (32%), Positives = 47/86 (54%), Gaps = 6/86 (6%)
Query 20 QLGGSNPQNVAEAATWAELA-GYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVRDIVYE 78
Q+ GS P V+ + D +++N+GCP VV+K S G+AL+ P ++++IV
Sbjct 407 QICGSYPDTVSRVVELIDRECTVDFIDINMGCPIDMVVNK-SAGSALLNKPLRMKNIVEV 465
Query 79 MKRRVQIPVTVKCRL----GVDNLDS 100
V+ P+T+K R G + +DS
Sbjct 466 SSSIVETPITIKVRTAFFEGKNRIDS 491
> mmu:66369 Dus2l, 2310016K04Rik; dihydrouridine synthase 2-like
(SMM1, S. cerevisiae); K05543 tRNA-dihydrouridine synthase
2 [EC:1.-.-.-]
Length=493
Score = 41.6 bits (96), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 6/79 (7%)
Query 17 IVCQLGGSNPQNVAEAATWAE--LAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVRD 74
+V Q+G S+ + A E +AG D +N+GCP KG GAAL+ P K+
Sbjct 84 VVFQMGTSDAERALAVARLVENDVAGID---VNMGCPK-EYSTKGGMGAALLSDPDKIEK 139
Query 75 IVYEMKRRVQIPVTVKCRL 93
I+ + + PVT K R+
Sbjct 140 ILSTLVKGTHRPVTCKIRI 158
> mmu:224907 Dus3l, AI662135, AW557805, MGC56820; dihydrouridine
synthase 3-like (S. cerevisiae); K05544 tRNA-dihydrouridine
synthase 3 [EC:1.-.-.-]
Length=637
Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Query 20 QLGGSNPQNVAEAATWA-ELAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVRDIVYE 78
QL G+ P + + A D V++NVGCP V KG G ALM K + IV
Sbjct 352 QLEGAFPDTMTKCAELLNRTIDVDFVDINVGCPIDLVYKKGG-GCALMNRSAKFQQIVRG 410
Query 79 MKRRVQIPVTVKCRLGV 95
+ + +P+TVK R GV
Sbjct 411 VNEVLDVPLTVKMRTGV 427
> xla:446385 dus1l, MGC83715; dihydrouridine synthase 1-like;
K05542 tRNA-dihydrouridine synthase 1 [EC:1.-.-.-]
Length=464
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 23/95 (24%), Positives = 49/95 (51%), Gaps = 4/95 (4%)
Query 14 EHPIVCQLGGSNPQNVAEAATWAELAGY-DEVNLNVGCPSCRVVDKGSFGAALMRSPTKV 72
+ P++ Q ++P+ +AA A+ Y D ++LN+GCP + +G +GA L +
Sbjct 67 DRPLIVQFCANDPEVFVQAALLAQ--DYCDAIDLNLGCPQ-MIAKRGHYGAFLQDEWDLL 123
Query 73 RDIVYEMKRRVQIPVTVKCRLGVDNLDSPEFTKQF 107
++ +++ +PVT K R+ + + ++ K
Sbjct 124 EKMIQLAHQKLSVPVTCKIRVFPEMEKTVQYAKML 158
> xla:432319 MGC132093; hypothetical protein MGC78973; K05542
tRNA-dihydrouridine synthase 1 [EC:1.-.-.-]
Length=465
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 22/94 (23%), Positives = 48/94 (51%), Gaps = 2/94 (2%)
Query 14 EHPIVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVR 73
+ P++ Q ++P+ +AA A+ D ++LN+GCP + +G +G+ L +
Sbjct 67 DRPLIVQFCANDPEVFVQAALLAQ-DYCDAIDLNLGCPQ-MIAKRGHYGSFLQDEWDLLE 124
Query 74 DIVYEMKRRVQIPVTVKCRLGVDNLDSPEFTKQF 107
++ +++ +PVT K R+ + + E+ K
Sbjct 125 KMIQLAHQKLSVPVTCKIRVFPEIEKTVEYAKML 158
> xla:734320 dus4l; dihydrouridine synthase 4-like; K05545 tRNA-dihydrouridine
synthase 4 [EC:1.-.-.-]
Length=308
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 23/84 (27%), Positives = 45/84 (53%), Gaps = 5/84 (5%)
Query 16 PIVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVRDI 75
P++ Q Q +A+AA+ ++LN GCP + +G +GA L+ +P V D+
Sbjct 73 PLIVQFAAKEAQVLADAASLVSPFA-SGIDLNCGCPQRWAMAEG-YGACLINNPELVSDM 130
Query 76 VYEMKRRV---QIPVTVKCRLGVD 96
V +++ +V + +++K R+ D
Sbjct 131 VRQVRNQVGSSEFTISIKIRIHAD 154
> sce:YNR015W SMM1, DUS2; Dihydrouridine synthase, member of a
family of dihydrouridine synthases including Dus1p, Smm1p,
Dus3p, and Dus4p; modifies uridine residues at position 20 of
cytoplasmic tRNAs (EC:1.-.-.-); K05543 tRNA-dihydrouridine
synthase 2 [EC:1.-.-.-]
Length=384
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 28/97 (28%), Positives = 51/97 (52%), Gaps = 10/97 (10%)
Query 17 IVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVRDIV 76
++ Q+G ++P +A A + +++N GCP + G G+AL+R+P + I+
Sbjct 85 LIFQIGSASPA-LATQAALKVINDVSGIDINAGCPKHFSIHSG-MGSALLRTPDTLCLIL 142
Query 77 YEMKRRV----QIPVTVKCRLGVDNLDSPEFTKQFVE 109
E+ + V P++VK RL LD+ + T Q V+
Sbjct 143 KELVKNVGNPHSKPISVKIRL----LDTKQDTLQLVK 175
> hsa:64118 DUS1L, DUS1, PP3111; dihydrouridine synthase 1-like
(S. cerevisiae); K05542 tRNA-dihydrouridine synthase 1 [EC:1.-.-.-]
Length=473
Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 22/81 (27%), Positives = 44/81 (54%), Gaps = 4/81 (4%)
Query 14 EHPIVCQLGGSNPQNVAEAATWAELAGY-DEVNLNVGCPSCRVVDKGSFGAALMRSPTKV 72
+ P++ Q ++P+ +AA A+ Y D ++LN+GCP + +G +GA L +
Sbjct 73 DRPLIVQFCANDPEVFVQAALLAQ--DYCDAIDLNLGCPQ-MIAKRGHYGAFLQDEWDLL 129
Query 73 RDIVYEMKRRVQIPVTVKCRL 93
+ ++ ++ +PVT K R+
Sbjct 130 QRMILLAHEKLSVPVTCKIRV 150
> dre:393647 MGC63779; zgc:63779; K05544 tRNA-dihydrouridine synthase
3 [EC:1.-.-.-]
Length=660
Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 23/54 (42%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query 42 DEVNLNVGCPSCRVVDKGSFGAALMRSPTKVRDIVYEMKRRVQIPVTVKCRLGV 95
D V++N GCP V KG G LM +K IV M + +P+TVK R GV
Sbjct 398 DFVDINSGCPIDLVYKKGG-GCGLMTRTSKFEQIVRGMNSVLDVPLTVKIRTGV 450
> tgo:TGME49_072570 hypothetical protein
Length=668
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 19/32 (59%), Positives = 22/32 (68%), Gaps = 1/32 (3%)
Query 44 VNLNVGCPSCRVVDKGSFGAALMRSPTKVRDI 75
VNLN GCPS RV KGSFG LM P +V ++
Sbjct 213 VNLNCGCPSPRVA-KGSFGLILMEDPKRVAEM 243
> mmu:71916 Dus4l, 2310069P03Rik, 2700089B10Rik, AI482040, MGC130363,
Pp35; dihydrouridine synthase 4-like (S. cerevisiae);
K05545 tRNA-dihydrouridine synthase 4 [EC:1.-.-.-]
Length=324
Score = 38.1 bits (87), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 23/84 (27%), Positives = 46/84 (54%), Gaps = 5/84 (5%)
Query 16 PIVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVRDI 75
P++ Q ++ + +++AA + +++N GCP + G +GA L+ P V D+
Sbjct 83 PLIVQFAANDARLLSDAALLV-CPYANGIDINCGCPQRWAMADG-YGACLINKPELVHDM 140
Query 76 VYEMKRRVQIP---VTVKCRLGVD 96
V +++ RV+ P V++K R+ D
Sbjct 141 VRQVRNRVESPRFSVSIKIRIHDD 164
> dre:322715 dus1l, wu:fb71f06, zgc:63748; dihydrouridine synthase
1-like (S. cerevisiae); K05542 tRNA-dihydrouridine synthase
1 [EC:1.-.-.-]
Length=479
Score = 37.4 bits (85), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 23/96 (23%), Positives = 47/96 (48%), Gaps = 6/96 (6%)
Query 1 SQYRTHTL--GFDDVEHPIVCQLGGSNPQNVAEAATWAELAGY-DEVNLNVGCPSCRVVD 57
+ YR L + + P++ Q ++P+ +AA A+ Y D ++LN+GCP +
Sbjct 58 ANYRRENLYSEVNQEDRPLITQFCANDPEVFIQAALLAQ--DYCDAIDLNLGCPQ-MIAK 114
Query 58 KGSFGAALMRSPTKVRDIVYEMKRRVQIPVTVKCRL 93
+G +G L + ++ ++ +P+T K R+
Sbjct 115 RGHYGVFLQDEWDLLEKMIKLANEKLSVPITCKIRV 150
> dre:100330185 dihydrouridine synthase 1-like (S. cerevisiae)-like;
K05542 tRNA-dihydrouridine synthase 1 [EC:1.-.-.-]
Length=496
Score = 37.0 bits (84), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 23/96 (23%), Positives = 47/96 (48%), Gaps = 6/96 (6%)
Query 1 SQYRTHTL--GFDDVEHPIVCQLGGSNPQNVAEAATWAELAGY-DEVNLNVGCPSCRVVD 57
+ YR L + + P++ Q ++P+ +AA A+ Y D ++LN+GCP +
Sbjct 75 ANYRRENLYSEVNQEDRPLITQFCANDPEVFIQAALLAQ--DYCDAIDLNLGCPQ-MIAK 131
Query 58 KGSFGAALMRSPTKVRDIVYEMKRRVQIPVTVKCRL 93
+G +G L + ++ ++ +P+T K R+
Sbjct 132 RGHYGVFLQDEWDLLEKMIKLANEKLSVPITCKIRV 167
> hsa:11062 DUS4L, DUS4, MGC133233, PP35; dihydrouridine synthase
4-like (S. cerevisiae); K05545 tRNA-dihydrouridine synthase
4 [EC:1.-.-.-]
Length=317
Score = 36.6 bits (83), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 22/84 (26%), Positives = 48/84 (57%), Gaps = 5/84 (5%)
Query 16 PIVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVRDI 75
P++ Q ++ + +++AA + +++N GCP + +G +GA L+ P V+D+
Sbjct 83 PLIVQFAANDARLLSDAARIV-CPYANGIDINCGCPQRWAMAEG-YGACLINKPELVQDM 140
Query 76 VYEMKRRVQIP---VTVKCRLGVD 96
V +++ +V+ P V++K R+ D
Sbjct 141 VKQVRNQVETPGFSVSIKIRIHDD 164
> tgo:TGME49_028080 hypothetical protein ; K05544 tRNA-dihydrouridine
synthase 3 [EC:1.-.-.-]
Length=1220
Score = 35.8 bits (81), Expect = 0.036, Method: Compositional matrix adjust.
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Query 20 QLGGSNPQ--NVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVRDIVY 77
Q+ G P+ N +E D ++LN CP ++ + GA ++ P ++ +V
Sbjct 879 QIAGGTPEVLNACTDILASEDVSCDFIDLNAACPLVQLHRRFKAGACMLDHPKRLESLVE 938
Query 78 EM-KRRVQIPVTVKCR 92
M R ++PVTVK R
Sbjct 939 SMTTRHPEVPVTVKLR 954
> sce:YLR401C DUS3; Dihydrouridine synthase, member of a widespread
family of conserved proteins including Smm1p, Dus1p, and
Dus4p; contains a consensus oleate response element (ORE)
in its promoter region (EC:1.-.-.-); K05544 tRNA-dihydrouridine
synthase 3 [EC:1.-.-.-]
Length=668
Score = 35.4 bits (80), Expect = 0.042, Method: Compositional matrix adjust.
Identities = 21/54 (38%), Positives = 32/54 (59%), Gaps = 2/54 (3%)
Query 43 EVNLNVGCPSCRVVDKGSFGAALMRSPTKVRDIVYEMKRRVQ-IPVTVKCRLGV 95
E+NLN GCP + +GS G+AL+ +P ++ + M + IP+TVK R G
Sbjct 379 EINLNSGCPIDLLYRQGS-GSALLDNPARMIRCLNAMNYVSKDIPITVKIRTGT 431
> cel:Y37E11B.5 hypothetical protein; K05544 tRNA-dihydrouridine
synthase 3 [EC:1.-.-.-]
Length=554
Score = 34.7 bits (78), Expect = 0.074, Method: Compositional matrix adjust.
Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 6/93 (6%)
Query 20 QLGGSNPQNVAEAATWA-ELAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVRDIVYE 78
QL G +A+A+ E D +++N+GCP VV++ G AL P K+ +++
Sbjct 264 QLAGGFADTMAKASQIVVENFDVDFIDINMGCP-IDVVNQKGGGCALPSRPQKLFEVLAA 322
Query 79 MKRRVQ--IPVTVKCRLGVDN--LDSPEFTKQF 107
K + P+TVK R G+ L +PE+ +
Sbjct 323 TKSVLGGCCPLTVKIRTGMKEGVLKAPEYVEHM 355
> hsa:1806 DPYD, DHP, DHPDHASE, DPD, MGC132008, MGC70799; dihydropyrimidine
dehydrogenase (EC:1.3.1.2); K00207 dihydropyrimidine
dehydrogenase (NADP+) [EC:1.3.1.2]
Length=1025
Score = 33.5 bits (75), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
Query 25 NPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVRDIVYEMKRRVQ 84
N + E A +E +G D + LN+ CP + + G A + P VR+I +++ VQ
Sbjct 646 NKNDWTELAKKSEDSGADALELNLSCP--HGMGERGMGLACGQDPELVRNICRWVRQAVQ 703
Query 85 IPVTVKCRLGVDNLDS 100
IP K V ++ S
Sbjct 704 IPFFAKLTPNVTDIVS 719
> mmu:99586 Dpyd, AI315208, DPD, E330028L06Rik, MGC37940; dihydropyrimidine
dehydrogenase (EC:1.3.1.2); K00207 dihydropyrimidine
dehydrogenase (NADP+) [EC:1.3.1.2]
Length=1025
Score = 32.7 bits (73), Expect = 0.32, Method: Compositional matrix adjust.
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
Query 25 NPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVRDIVYEMKRRVQ 84
N + E + AE +G D + LN+ CP + + G A + P VR+I +++ V+
Sbjct 646 NKSDWMELSKMAEASGADALELNLSCP--HGMGERGMGLACGQDPELVRNICRWVRQAVR 703
Query 85 IPVTVKCRLGVDNLDS 100
+P K V ++ S
Sbjct 704 VPFFAKLTPNVTDIVS 719
> cel:C25F6.3 dpyd-1; DihydroPYrimidine Dehydrogenase family member
(dpyd-1); K00207 dihydropyrimidine dehydrogenase (NADP+)
[EC:1.3.1.2]
Length=1059
Score = 32.3 bits (72), Expect = 0.41, Method: Compositional matrix adjust.
Identities = 23/62 (37%), Positives = 35/62 (56%), Gaps = 2/62 (3%)
Query 25 NPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVRDIVYEMKRRVQ 84
N + E AT +E AG D + LN+ CP + +KG G A +SP V++I ++ V+
Sbjct 660 NKADWIELATKSEEAGADILELNLSCPH-GMGEKG-MGLACGQSPEIVKEICRWVRACVK 717
Query 85 IP 86
IP
Sbjct 718 IP 719
> xla:447312 dpyd, MGC81821, dhp, dhpdhase, dpd; dihydropyrimidine
dehydrogenase (EC:1.3.1.2); K00207 dihydropyrimidine dehydrogenase
(NADP+) [EC:1.3.1.2]
Length=940
Score = 32.0 bits (71), Expect = 0.55, Method: Compositional matrix adjust.
Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
Query 8 LGFDDVEHPIVCQLGGS-NPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALM 66
L D +H I+ + S N + E + AE +G + + LN+ CP + + G A
Sbjct 628 LKADFPKHIIIASIMCSYNKDDWTELSLMAEASGANALELNLSCP--HGMGERGMGLACG 685
Query 67 RSPTKVRDIVYEMKRRVQIPVTVK 90
+ P VR+I +++ V+IP K
Sbjct 686 QDPELVRNICRWVRQAVKIPFFAK 709
> eco:b2147 yeiA, dpdB, ECK2140, JW2134; dihydropyrimidine dehydrogenase,
NADH-dependent, subunit B
Length=411
Score = 31.2 bits (69), Expect = 0.84, Method: Compositional matrix adjust.
Identities = 19/74 (25%), Positives = 32/74 (43%), Gaps = 3/74 (4%)
Query 17 IVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALMRSPTKVRDIV 76
++ + G N Q E A + AG D + N CP + + G+ + +SP V
Sbjct 104 LIASIMGENEQQWEELARLVQEAGADMIECNFSCPQ---MTSHAMGSDVGQSPELVEKYC 160
Query 77 YEMKRRVQIPVTVK 90
+KR +P+ K
Sbjct 161 RAVKRGSTLPMLAK 174
> dre:556707 hypothetical LOC556707
Length=499
Score = 30.8 bits (68), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 24/96 (25%), Positives = 36/96 (37%), Gaps = 5/96 (5%)
Query 7 TLGFDDVEHPIVCQLGGSNPQNVAEAATWAELAGYDEVNLNVGCPSCRVVDKGSFGAALM 66
L D P+ + S A +W L +DE +N C ++D +
Sbjct 132 ALKLHDRNQPVTLDMRHS-----ALCHSWLSLRLFDEGTINKWKDCCTMIDHANGATNYF 186
Query 67 RSPTKVRDIVYEMKRRVQIPVTVKCRLGVDNLDSPE 102
SPT V D YE V + K + GV ++ E
Sbjct 187 FSPTLVADWFYESISMVLAEIQKKPQRGVPRVEKVE 222
> dre:405829 dpyd, MGC77205, zgc:77205; dihydropyrimidine dehydrogenase
(EC:1.3.1.2); K00207 dihydropyrimidine dehydrogenase
(NADP+) [EC:1.3.1.2]
Length=1022
Score = 30.8 bits (68), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 16/95 (16%)
Query 18 VCQLGGSNPQNVAEA--------ATWAELAGY------DEVNLNVGCPSCRVVDKGSFGA 63
V +L P+N+ A A W ELA D + LN+ CP + + G
Sbjct 625 VAELKADFPKNIIIASIMCSYNQADWTELAKMAQESQADALELNLSCP--HGMGERGMGL 682
Query 64 ALMRSPTKVRDIVYEMKRRVQIPVTVKCRLGVDNL 98
A + P VR+I +++ IP K V N+
Sbjct 683 ACGQDPELVRNICRWVRKATSIPFFAKLTPNVTNI 717
Lambda K H
0.319 0.135 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 2072286120
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
Posted date: Sep 17, 2011 2:57 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40