bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
164,496 sequences; 82,071,388 total letters
Query= Eten_5414_orf1
Length=168
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_068370 hypothetical protein ; K08874 transformation... 137 1e-32
cpv:cgd6_1740 Tra1p-like; C-terminal FAT domain plus phoshoino... 109 4e-24
bbo:BBOV_III007660 17.m07668; hypothetical protein; K08874 tra... 64.3 2e-10
ath:AT2G17930 binding / inositol or phosphatidylinositol kinas... 62.0 9e-10
pfa:MAL13P1.19 peptidase, putative 56.6 4e-08
ath:AT4G36080 FAT domain-containing protein / phosphatidylinos... 52.8 5e-07
tpv:TP04_0665 hypothetical protein; K08874 transformation/tran... 52.0 1e-06
dre:569810 smg1, zgc:152973; PI-3-kinase-related kinase SMG-1 ... 51.2 1e-06
sce:YKL203C TOR2, DRR2; PIK-related protein kinase and rapamyc... 50.8 2e-06
bbo:BBOV_III011480 17.m07979; phosphatidylinositol 3- and 4-ki... 49.3 5e-06
sce:YJR066W TOR1, DRR1; PIK-related protein kinase and rapamyc... 49.3 6e-06
cel:B0261.2 let-363; LEThal family member (let-363); K07203 FK... 48.5 1e-05
dre:324254 mtor, fc22h08, frap1, tor, wu:fc22h08; mechanistic ... 48.1 1e-05
hsa:2475 MTOR, FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1; mec... 47.8 2e-05
mmu:56717 Mtor, 2610315D21Rik, AI327068, FRAP, FRAP2, Frap1, M... 47.8 2e-05
hsa:731751 DNA-dependent protein kinase catalytic subunit-like... 47.0 3e-05
hsa:5591 PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p3... 47.0 3e-05
dre:562283 fa96e12; wu:fa96e12; K06642 DNA-dependent protein k... 47.0 3e-05
mmu:19090 Prkdc, AI326420, AU019811, DNA-PKcs, DNAPDcs, DNAPK,... 46.6 4e-05
sce:YHR099W TRA1; Subunit of SAGA and NuA4 histone acetyltrans... 45.4 8e-05
cpv:cgd4_2670 FRP1 like protein involved in DNA repair with a ... 45.1 1e-04
sce:YBL088C TEL1; Protein kinase primarily involved in telomer... 45.1 1e-04
hsa:23049 SMG1, 61E3.4, ATX, KIAA0421, LIP; SMG1 homolog, phos... 44.7 1e-04
mmu:233789 Smg1, 2610207I05Rik, 5430435M13Rik, C130002K18Rik, ... 44.7 2e-04
ath:AT3G48190 ATM; ATM (ATAXIA-TELANGIECTASIA MUTATED); 1-phos... 44.3 2e-04
xla:373602 prkdc, dna-pkcs, dnapk, dnpk1, hyrc, hyrc1, p350, p... 43.9 2e-04
tgo:TGME49_116440 phosphatidylinositol 3- and 4-kinase domain-... 43.5 3e-04
ath:AT1G50030 TOR; TOR (TARGET OF RAPAMYCIN); 1-phosphatidylin... 43.5 3e-04
dre:557263 fc54d09; wu:fc54d09; K08874 transformation/transcri... 42.0 9e-04
tgo:TGME49_048530 phosphatidylinositol 3- and 4-kinase domain-... 42.0 9e-04
mmu:100683 Trrap, AI481500; transformation/transcription domai... 41.2 0.002
hsa:8295 TRRAP, FLJ10671, PAF350/400, PAF400, STAF40, TR-AP, T... 40.4 0.002
sce:YBR136W MEC1, ESR1, SAD3; Genome integrity checkpoint prot... 39.3 0.006
xla:398148 atm, Xatm, at1, atdc, tel1, telo1; ataxia telangiec... 38.9 0.009
tgo:TGME49_083700 phosphatidylinositol 3- and 4-kinase domain-... 37.4 0.023
bbo:BBOV_IV009520 23.m05829; phosphatidylinositol 4 kinase (EC... 37.4 0.027
cel:C47D12.1 trr-1; TRRAP-like (transcription/transformation d... 35.8 0.076
ath:AT5G40820 ATRAD3; ATRAD3; binding / inositol or phosphatid... 34.7 0.16
dre:563201 pi4kb, pik4cb, zgc:152715; phosphatidylinositol 4-k... 33.1 0.41
hsa:651610 serine-protein kinase ATM-like; K04728 ataxia telan... 33.1 0.48
hsa:472 ATM, AT1, ATA, ATC, ATD, ATDC, ATE, DKFZp781A0353, MGC... 33.1 0.51
tpv:TP01_0820 phosphatidylinositol 4-kinase; K00888 phosphatid... 32.7 0.56
dre:567770 atr, si:dkey-231j24.1; ataxia telangiectasia and Ra... 32.7 0.57
cel:F33H1.4 hypothetical protein 32.3 0.68
xla:398197 atr, XATR, frp1, mec1, sckl, sckl1; ataxia telangie... 32.3 0.74
xla:444446 pi4kb, MGC83640, PI4K-beta, PI4Kbeta, pik4cb; phosp... 32.0 1.1
tgo:TGME49_028690 phosphatidylinositol 3- and 4-kinase domain-... 31.6 1.3
cel:F35H12.4 hypothetical protein; K00888 phosphatidylinositol... 31.6 1.3
pfa:PFE0485w phosphatidylinositol 4-kinase, putative (EC:2.7.1... 31.2 1.8
tgo:TGME49_066000 phosphatidylinositol 3- and 4-kinase domain-... 30.0 3.8
> tgo:TGME49_068370 hypothetical protein ; K08874 transformation/transcription
domain-associated protein
Length=8430
Score = 137 bits (345), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 62/127 (48%), Positives = 89/127 (70%), Gaps = 0/127 (0%)
Query 3 EELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLA 62
+ELFVF+++FTQS ++ +LNY+ M DI+P+K+ L L+TG Q ELK CY ++L L
Sbjct 8209 DELFVFRKRFTQSVGLFGLLNYILSMADINPSKIRLSLETGVVSQLELKPCYNGSTLSLD 8268
Query 63 FGDRIPFRLTRNIELLIDVFGRAGLLPGCMYTLVCCLQSYSSHFSNAAALLIRDDVAFFY 122
F +R+PFRLTRNIE LI FGR G+LP +++ V CL+ Y H S+A L +RDD+ F+
Sbjct 8269 FVERVPFRLTRNIESLIGPFGRLGVLPSVIFSFVRCLRRYKDHLSSALCLFVRDDITAFH 8328
Query 123 RQKQQQQ 129
Q++ Q
Sbjct 8329 IQRKLQH 8335
> cpv:cgd6_1740 Tra1p-like; C-terminal FAT domain plus phoshoinositide
3-kinase domain; very large protein ; K08874 transformation/transcription
domain-associated protein
Length=5542
Score = 109 bits (272), Expect = 4e-24, Method: Composition-based stats.
Identities = 53/137 (38%), Positives = 82/137 (59%), Gaps = 2/137 (1%)
Query 3 EELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLA 62
++ F+F +QFT + I +Y+ + D++P K+ + L TGQ Q+ELK+ Y +++LL+
Sbjct 5302 DQSFLFTKQFTTHLGLLSIFSYILGVNDVTPGKLFISLDTGQVYQSELKSSYVSSTLLID 5361
Query 63 FGDRIPFRLTRNIELLIDVFGRAGLLPGCMYTLVCCLQSYSSHFSNAAALLIRDDVAFF- 121
+++PFRLTRN+E L+ FG+ G+LPG M CLQ Y H N L+RDD+ F
Sbjct 5362 KTEKVPFRLTRNMEHLMGPFGKNGILPGTMLAFAQCLQKYEFHVRNLLCSLLRDDLHAFS 5421
Query 122 -YRQKQQQQQQLLLLAP 137
+R Q Q + L P
Sbjct 5422 VHRALQIPQNRNLYQKP 5438
> bbo:BBOV_III007660 17.m07668; hypothetical protein; K08874 transformation/transcription
domain-associated protein
Length=3963
Score = 64.3 bits (155), Expect = 2e-10, Method: Composition-based stats.
Identities = 30/117 (25%), Positives = 60/117 (51%), Gaps = 1/117 (0%)
Query 1 GAEELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLL 60
G ++ +R FT S+++ +L +F P +P+K+ + GQ Q + K Y + +
Sbjct 3748 GYQDFMTMRRMFTSSYSIQALLGLMFLTPYATPSKLSFNFHNGQVNQLDFKPNY-SREIF 3806
Query 61 LAFGDRIPFRLTRNIELLIDVFGRAGLLPGCMYTLVCCLQSYSSHFSNAAALLIRDD 117
+ + FR TRNI+ +I R G++P +Y L + ++ +A ++++ DD
Sbjct 3807 VEYSKLRVFRFTRNIKTMIGPVCRMGIMPAVIYALCAAIHTHKVDILSALSVILADD 3863
> ath:AT2G17930 binding / inositol or phosphatidylinositol kinase/
phosphotransferase, alcohol group as acceptor; K08874 transformation/transcription
domain-associated protein
Length=3795
Score = 62.0 bits (149), Expect = 9e-10, Method: Composition-based stats.
Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Query 5 LFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLAFG 64
++ FK+QF AV ++++ + SPNKVL TG+ Q + Y A+ ++ F
Sbjct 3589 MWAFKKQFAVQLAVSSFMSFMLQIGGRSPNKVLFAKNTGKMFQTDFHPAY-DANGMIEFN 3647
Query 65 DRIPFRLTRNIELLIDVFGRAGLLPGCMYTLVCCLQS--YSSHFSNAAALLIRDDVAFFY 122
+ +PFRLTRN++ FG GLL M + + S + H A+ RD++ ++
Sbjct 3648 EPVPFRLTRNMQAFFSQFGVEGLLMSSMCSAAQAVISSKQNEHLRYQLAMFFRDELLSWF 3707
Query 123 RQK 125
++
Sbjct 3708 GRR 3710
> pfa:MAL13P1.19 peptidase, putative
Length=9271
Score = 56.6 bits (135), Expect = 4e-08, Method: Composition-based stats.
Identities = 34/132 (25%), Positives = 65/132 (49%), Gaps = 3/132 (2%)
Query 3 EELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLA 62
E +F QF +++++ C+LNY+F + + + +++ +G++ E + Y ++
Sbjct 8801 ENYSIFHDQFVKNYSILCMLNYVFFQLNTNLDNIVISKCSGRSGYCEGRPLYKDFTMKKD 8860
Query 63 FG-DRIPFRLTRNIELLIDVFGRAGLLPGCMYTLVCCLQSYSSHFSNAAALLIRDDVAFF 121
++ FRLTRNI+ I G G P C Y+ + ++ N L I DD FF
Sbjct 8861 INRKKLAFRLTRNIKEFIGFQGLHGSFPLCFYSSIMAIKKKKMEIKNFLNLAISDD--FF 8918
Query 122 YRQKQQQQQQLL 133
Q++ + L+
Sbjct 8919 TLHVQKKNRNLM 8930
> ath:AT4G36080 FAT domain-containing protein / phosphatidylinositol
3- and 4-kinase family protein; K08874 transformation/transcription
domain-associated protein
Length=3839
Score = 52.8 bits (125), Expect = 5e-07, Method: Composition-based stats.
Identities = 36/145 (24%), Positives = 66/145 (45%), Gaps = 7/145 (4%)
Query 5 LFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLAFG 64
L+ FK+QF AV ++++ + SPNK+L +G+ Q + Y ++ ++
Sbjct 3633 LWAFKKQFAVQLAVSNFMSFILQIGGRSPNKILFAKNSGKMFQTDFHPSY-DSNGMIELN 3691
Query 65 DRIPFRLTRNIELLIDVFGRAGLLPG--CMYTLVCCLQSYSSHFSNAAALLIRDDVAFFY 122
+ +PFRLTRN+ + FG G L C + + H A+ RD++ ++
Sbjct 3692 EPVPFRLTRNMHAFLSHFGVEGPLMSNMCSASQAVFSSKQNEHLRYQLAMFFRDELLSWF 3751
Query 123 RQKQQQQQQLLLLAPAAAAATRRKP 147
++ + + P A AT P
Sbjct 3752 GRRPLG----VPIPPVAGIATLSSP 3772
> tpv:TP04_0665 hypothetical protein; K08874 transformation/transcription
domain-associated protein
Length=3928
Score = 52.0 bits (123), Expect = 1e-06, Method: Composition-based stats.
Identities = 39/138 (28%), Positives = 62/138 (44%), Gaps = 19/138 (13%)
Query 3 EELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLA 62
E F+ FT S+A +LN +F P +P+K++L++ G Q + K
Sbjct 3712 ENFMNFRINFTSSYATQALLNLVFATPYSTPSKLVLNMNNGSIRQFDFK----------L 3761
Query 63 FGDRIP------FRLTRNIELLIDVFGRAGLLPGCMYTLVCCLQSYS--SHFSNAAALLI 114
F + FRLTRN+ + R GLLPG M+ + + + H + +A L+
Sbjct 3762 FNREMDDNKIRVFRLTRNMTNFMGPTCRLGLLPGVMFAVSSSIHHFKIDVHAALSAILIG 3821
Query 115 RDDVAFFYR-QKQQQQQQ 131
R FY QK ++ Q
Sbjct 3822 RSTSRDFYAFQKDKENLQ 3839
> dre:569810 smg1, zgc:152973; PI-3-kinase-related kinase SMG-1
(EC:2.7.11.1); K08873 PI-3-kinase-related kinase SMG-1
Length=3640
Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Query 4 ELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLAF 63
E + + + +S AV ++ Y+ + D + VL+D+ TG+ + + C+ L
Sbjct 2287 EWWSVTQTYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGK-SLRV 2345
Query 64 GDRIPFRLTRNIELLIDVFGRAGL 87
+++PFR+T NIE + V G G+
Sbjct 2346 PEKVPFRMTHNIETALGVTGVEGI 2369
> sce:YKL203C TOR2, DRR2; PIK-related protein kinase and rapamycin
target; subunit of TORC1, a complex that regulates growth
in response to nutrients and TORC2, a complex that regulates
cell-cycle dependent polarization of the actin cytoskeleton;
involved in meiosis (EC:2.7.11.1 2.7.1.67); K07203 FKBP12-rapamycin
complex-associated protein
Length=2474
Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats.
Identities = 25/78 (32%), Positives = 44/78 (56%), Gaps = 0/78 (0%)
Query 9 KRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLAFGDRIP 68
+ +T+S AV + Y+ + D P+ ++LD TG+ + + C+ AA L F +++P
Sbjct 2258 RTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKFPEKVP 2317
Query 69 FRLTRNIELLIDVFGRAG 86
FRLTR + ++V G G
Sbjct 2318 FRLTRMLTYAMEVSGIEG 2335
> bbo:BBOV_III011480 17.m07979; phosphatidylinositol 3- and 4-kinase
family protein
Length=3440
Score = 49.3 bits (116), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Query 6 FVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLAFGD 65
F +++F + AV+ IL Y+ + D +LL+L TGQ + + C L LA +
Sbjct 3228 FTARKEFIHTCAVWSILGYIVGLGDRHAENILLNLLTGQIMHVDFD-CLFGKGLQLAVPE 3286
Query 66 RIPFRLTRNIELLIDVFGRAGLLP 89
+PFR+T+N+ + V G A P
Sbjct 3287 LVPFRMTQNVVCNLGVCGTANDGP 3310
> sce:YJR066W TOR1, DRR1; PIK-related protein kinase and rapamycin
target; subunit of TORC1, a complex that controls growth
in response to nutrients by regulating translation, transcription,
ribosome biogenesis, nutrient transport and autophagy;
involved in meiosis (EC:2.7.1.137); K07203 FKBP12-rapamycin
complex-associated protein
Length=2470
Score = 49.3 bits (116), Expect = 6e-06, Method: Composition-based stats.
Identities = 24/78 (30%), Positives = 44/78 (56%), Gaps = 0/78 (0%)
Query 9 KRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLAFGDRIP 68
+ +T+S AV + Y+ + D P+ ++LD TG+ + + C+ AA L + +++P
Sbjct 2254 RTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKYPEKVP 2313
Query 69 FRLTRNIELLIDVFGRAG 86
FRLTR + ++V G G
Sbjct 2314 FRLTRMLTYAMEVSGIEG 2331
> cel:B0261.2 let-363; LEThal family member (let-363); K07203
FKBP12-rapamycin complex-associated protein
Length=2695
Score = 48.5 bits (114), Expect = 1e-05, Method: Composition-based stats.
Identities = 26/86 (30%), Positives = 47/86 (54%), Gaps = 0/86 (0%)
Query 2 AEELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLL 61
+E F + +T+S A ++ Y+ + D P+ ++LD TG+ + + C+ A L
Sbjct 2485 SEVWFDRRTNYTRSVACMSMVGYILGLGDRHPSNLMLDRLTGKVVHIDFGDCFEVAMLRE 2544
Query 62 AFGDRIPFRLTRNIELLIDVFGRAGL 87
F +R+PFRLTR + ++V G G+
Sbjct 2545 KFPERVPFRLTRMLINAMEVTGLDGV 2570
> dre:324254 mtor, fc22h08, frap1, tor, wu:fc22h08; mechanistic
target of rapamycin (serine/threonine kinase); K07203 FKBP12-rapamycin
complex-associated protein
Length=2515
Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats.
Identities = 26/85 (30%), Positives = 46/85 (54%), Gaps = 0/85 (0%)
Query 2 AEELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLL 61
+E F + +T+S AV ++ Y+ + D P+ ++LD +G+ L + C+ A
Sbjct 2276 SEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTRE 2335
Query 62 AFGDRIPFRLTRNIELLIDVFGRAG 86
F ++IPFRLTR + ++V G G
Sbjct 2336 KFPEKIPFRLTRMLTNAMEVTGLDG 2360
> hsa:2475 MTOR, FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1; mechanistic
target of rapamycin (serine/threonine kinase) (EC:2.7.11.1);
K07203 FKBP12-rapamycin complex-associated protein
Length=2549
Score = 47.8 bits (112), Expect = 2e-05, Method: Composition-based stats.
Identities = 26/85 (30%), Positives = 46/85 (54%), Gaps = 0/85 (0%)
Query 2 AEELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLL 61
+E F + +T+S AV ++ Y+ + D P+ ++LD +G+ L + C+ A
Sbjct 2310 SEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTRE 2369
Query 62 AFGDRIPFRLTRNIELLIDVFGRAG 86
F ++IPFRLTR + ++V G G
Sbjct 2370 KFPEKIPFRLTRMLTNAMEVTGLDG 2394
> mmu:56717 Mtor, 2610315D21Rik, AI327068, FRAP, FRAP2, Frap1,
MGC118056, RAFT1, RAPT1, flat; mechanistic target of rapamycin
(serine/threonine kinase) (EC:2.7.11.1); K07203 FKBP12-rapamycin
complex-associated protein
Length=2549
Score = 47.8 bits (112), Expect = 2e-05, Method: Composition-based stats.
Identities = 26/85 (30%), Positives = 46/85 (54%), Gaps = 0/85 (0%)
Query 2 AEELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLL 61
+E F + +T+S AV ++ Y+ + D P+ ++LD +G+ L + C+ A
Sbjct 2310 SEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTRE 2369
Query 62 AFGDRIPFRLTRNIELLIDVFGRAG 86
F ++IPFRLTR + ++V G G
Sbjct 2370 KFPEKIPFRLTRMLTNAMEVTGLDG 2394
> hsa:731751 DNA-dependent protein kinase catalytic subunit-like;
K06642 DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
Length=4096
Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 27/126 (21%), Positives = 58/126 (46%), Gaps = 1/126 (0%)
Query 3 EELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLA 62
E + F SHA+ CI +++ + D N ++ ++TG + + + +A+ L
Sbjct 3863 EAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLP 3922
Query 63 FGDRIPFRLTRNIELLIDVFGRAGLLPGCMYTLVCCLQSYSSHFSNAAALLIRDDVAFFY 122
+ +PFRLTR L+ GL+ M + +S +N + +++ +F +
Sbjct 3923 VPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEP-SFDW 3981
Query 123 RQKQQQ 128
+ +Q+
Sbjct 3982 KNFEQK 3987
> hsa:5591 PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7,
p350; protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1);
K06642 DNA-dependent protein kinase catalytic
subunit [EC:2.7.11.1]
Length=4097
Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 27/126 (21%), Positives = 58/126 (46%), Gaps = 1/126 (0%)
Query 3 EELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLA 62
E + F SHA+ CI +++ + D N ++ ++TG + + + +A+ L
Sbjct 3864 EAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLP 3923
Query 63 FGDRIPFRLTRNIELLIDVFGRAGLLPGCMYTLVCCLQSYSSHFSNAAALLIRDDVAFFY 122
+ +PFRLTR L+ GL+ M + +S +N + +++ +F +
Sbjct 3924 VPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEP-SFDW 3982
Query 123 RQKQQQ 128
+ +Q+
Sbjct 3983 KNFEQK 3988
> dre:562283 fa96e12; wu:fa96e12; K06642 DNA-dependent protein
kinase catalytic subunit [EC:2.7.11.1]
Length=4119
Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 0/90 (0%)
Query 3 EELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLA 62
E + F+ SHAV CI +++ + D + +++ +TG + + + +A+ L
Sbjct 3886 EAFLSLRSHFSSSHAVLCISHWILGIGDRHLSNFMINTETGGMIGIDFGHAFGSATQFLP 3945
Query 63 FGDRIPFRLTRNIELLIDVFGRAGLLPGCM 92
+ +PFRLTR L+ +GL+ M
Sbjct 3946 VPELMPFRLTRQFINLMRPLAESGLIQSVM 3975
> mmu:19090 Prkdc, AI326420, AU019811, DNA-PKcs, DNAPDcs, DNAPK,
DNPK1, DOXNPH, HYRC1, XRCC7, dxnph, p460, scid, slip; protein
kinase, DNA activated, catalytic polypeptide (EC:2.7.11.1);
K06642 DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
Length=4128
Score = 46.6 bits (109), Expect = 4e-05, Method: Composition-based stats.
Identities = 29/122 (23%), Positives = 55/122 (45%), Gaps = 8/122 (6%)
Query 3 EELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLA 62
E + F SHA+ CI ++L + D N ++ ++TG + + + +A+ L
Sbjct 3895 EAFLALRSHFASSHALLCISHWLLGIGDRHLNNFMVAMETGSVIGIDFGHAFGSATQFLP 3954
Query 63 FGDRIPFRLTRNIELLIDVFGRAGLLPGCMYTLVCCLQSYSSHFSNAAALLIRDDVAFFY 122
+ +PFRLTR L +LP L+C + ++ + A L+ D + F
Sbjct 3955 VPELMPFRLTRQFVSL--------MLPMKETGLMCTVMVHALRAFRSCAGLLTDTMEIFV 4006
Query 123 RQ 124
++
Sbjct 4007 KE 4008
> sce:YHR099W TRA1; Subunit of SAGA and NuA4 histone acetyltransferase
complexes; interacts with acidic activators (e.g.,
Gal4p) which leads to transcription activation; similar to human
TRRAP, which is a cofactor for C-Myc mediated oncogenic
transformation; K08874 transformation/transcription domain-associated
protein
Length=3744
Score = 45.4 bits (106), Expect = 8e-05, Method: Composition-based stats.
Identities = 31/137 (22%), Positives = 63/137 (45%), Gaps = 17/137 (12%)
Query 3 EELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAEL---KACYCAASL 59
E+ ++F++QF ++ + ++Y+ + + +P+K+ +D +G E+ + Y
Sbjct 3539 EDFWLFRKQFASQYSSFVFMSYMMMINNRTPHKIHVDKTSGNVFTLEMLPSRFPYERVKP 3598
Query 60 LLAFGD--------------RIPFRLTRNIELLIDVFGRAGLLPGCMYTLVCCLQSYSSH 105
LL D +PFRLT NI+ LI G+ ++T+ L +
Sbjct 3599 LLKNHDLSLPPDSPIFHNNEPVPFRLTPNIQSLIGDSALEGIFAVNLFTISRALIEPDNE 3658
Query 106 FSNAAALLIRDDVAFFY 122
+ AL IRD++ ++
Sbjct 3659 LNTYLALFIRDEIISWF 3675
> cpv:cgd4_2670 FRP1 like protein involved in DNA repair with
a FAT domain and a phosphatidylinositol kinase domain at the
C-terminus
Length=3461
Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats.
Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query 9 KRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLAFGDRIP 68
K ++T+S AV+ + Y+ + D +L+D Q G + + C LL + +P
Sbjct 3244 KEKYTKSTAVWSMFGYIVGLGDRHAENILIDTQVGDIIHVDFD-CLFGKGFLLEIPEIVP 3302
Query 69 FRLTRNIELLIDVFGRAGLLPGCMYTLVCCLQSYSSHFSNA 109
FRLT NI + + G G G T + + + S F+ +
Sbjct 3303 FRLTPNIVIAMGSCGVEGTFTG---TSISSMSIFRSPFNKS 3340
> sce:YBL088C TEL1; Protein kinase primarily involved in telomere
length regulation; contributes to cell cycle checkpoint
control in response to DNA damage; functionally redundant with
Mec1p; homolog of human ataxia telangiectasia (ATM) gene
(EC:2.7.11.1); K04728 ataxia telangectasia mutated family protein
[EC:2.7.11.1]
Length=2787
Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats.
Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 4/82 (4%)
Query 6 FVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLAFGD 65
F K+ +T+ A I+ Y+ + D N +LLD TG+ + +L + LL +
Sbjct 2588 FEAKKTYTKGVAASSIVGYILGLGDRHLNNILLDCSTGEPIHIDLGIAFDQGK-LLPIPE 2646
Query 66 RIPFRLTRNIELLIDVFGRAGL 87
+PFRLTR+I +D FG G+
Sbjct 2647 LVPFRLTRDI---VDGFGVTGV 2665
> hsa:23049 SMG1, 61E3.4, ATX, KIAA0421, LIP; SMG1 homolog, phosphatidylinositol
3-kinase-related kinase (C. elegans) (EC:2.7.11.1);
K08873 PI-3-kinase-related kinase SMG-1
Length=3661
Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats.
Identities = 23/86 (26%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
Query 3 EELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLA 62
+E + + + +S AV ++ Y+ + D + VL+D+ TG+ + + C+ L
Sbjct 2308 DEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCF-EKGKSLR 2366
Query 63 FGDRIPFRLTRNIELLIDVFGRAGLL 88
+++PFR+T+NIE + V G G+
Sbjct 2367 VPEKVPFRMTQNIETALGVTGVEGVF 2392
> mmu:233789 Smg1, 2610207I05Rik, 5430435M13Rik, C130002K18Rik,
mKIAA0421; SMG1 homolog, phosphatidylinositol 3-kinase-related
kinase (C. elegans) (EC:2.7.11.1); K08873 PI-3-kinase-related
kinase SMG-1
Length=3658
Score = 44.7 bits (104), Expect = 2e-04, Method: Composition-based stats.
Identities = 23/86 (26%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
Query 3 EELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLA 62
+E + + + +S AV ++ Y+ + D + VL+D+ TG+ + + C+ L
Sbjct 2306 DEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCF-EKGKSLR 2364
Query 63 FGDRIPFRLTRNIELLIDVFGRAGLL 88
+++PFR+T+NIE + V G G+
Sbjct 2365 VPEKVPFRMTQNIETALGVTGVEGVF 2390
> ath:AT3G48190 ATM; ATM (ATAXIA-TELANGIECTASIA MUTATED); 1-phosphatidylinositol-3-phosphate
5-kinase; K04728 ataxia telangectasia
mutated family protein [EC:2.7.11.1]
Length=3845
Score = 44.3 bits (103), Expect = 2e-04, Method: Composition-based stats.
Identities = 33/108 (30%), Positives = 54/108 (50%), Gaps = 7/108 (6%)
Query 6 FVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLAFGD 65
FV + +T+S A ++ Y+ + D +L+D T + + +L + L+L +
Sbjct 3646 FVKRLAYTRSVAASSMVGYIVGLGDRHAMNILIDQATAEVVHIDLGVAF-EQGLMLKTPE 3704
Query 66 RIPFRLTRNIELLIDVFGRAGLLPGCMYTLVCCLQSYSSHFSNAAALL 113
R+PFRLTR+I ID G G + G CC ++ S +N ALL
Sbjct 3705 RVPFRLTRDI---IDGMGITG-VEGVFRR--CCEETLSVMRTNKEALL 3746
> xla:373602 prkdc, dna-pkcs, dnapk, dnpk1, hyrc, hyrc1, p350,
prkdc-A, xrcc7; protein kinase, DNA-activated, catalytic polypeptide
(EC:2.7.11.1); K06642 DNA-dependent protein kinase
catalytic subunit [EC:2.7.11.1]
Length=4146
Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats.
Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 3/102 (2%)
Query 3 EELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLA 62
E + F +SHA+ C+ +++ + D + +++++TG + + + A+ L
Sbjct 3913 EAFLSLRSHFARSHALLCVSHWIVGIGDRHLSNFMINMETGGMIGIDFGHAFGTATQFLP 3972
Query 63 FGDRIPFRLTRNIELLIDVFGRAGLLPGCMYTLVCCLQSYSS 104
+ +PFRLTR I L+ +GL M V L++Y S
Sbjct 3973 VPELMPFRLTRQIVNLMLPMKDSGLFDSVM---VHSLRAYRS 4011
> tgo:TGME49_116440 phosphatidylinositol 3- and 4-kinase domain-containing
protein (EC:4.1.1.70 2.7.11.1)
Length=2896
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 21/74 (28%), Positives = 40/74 (54%), Gaps = 0/74 (0%)
Query 2 AEELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLL 61
+EE + + F +S AV ++ Y+ + D P+ +LL ++G+ + C+ A+
Sbjct 2573 SEEWLLHRANFCKSVAVMSMVGYILGLGDRHPSNLLLMGESGRVAHIDFSDCFEVAAYRP 2632
Query 62 AFGDRIPFRLTRNI 75
+++PFRLTR I
Sbjct 2633 RCPEKVPFRLTRMI 2646
> ath:AT1G50030 TOR; TOR (TARGET OF RAPAMYCIN); 1-phosphatidylinositol-3-kinase/
protein binding; K07203 FKBP12-rapamycin
complex-associated protein
Length=2454
Score = 43.5 bits (101), Expect = 3e-04, Method: Composition-based stats.
Identities = 24/86 (27%), Positives = 49/86 (56%), Gaps = 1/86 (1%)
Query 2 AEELFVFKR-QFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLL 60
+ E+++ +R +T+S AV ++ Y+ + D P+ ++L +G+ L + C+ A+
Sbjct 2191 SSEVWLERRTNYTRSLAVMSMVGYILGLGDRHPSNLMLHRYSGKILHIDFGDCFEASMNR 2250
Query 61 LAFGDRIPFRLTRNIELLIDVFGRAG 86
F +++PFRLTR + ++V G G
Sbjct 2251 EKFPEKVPFRLTRMLVKAMEVSGIEG 2276
> dre:557263 fc54d09; wu:fc54d09; K08874 transformation/transcription
domain-associated protein
Length=3823
Score = 42.0 bits (97), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 32/144 (22%), Positives = 62/144 (43%), Gaps = 12/144 (8%)
Query 1 GAEELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLL 60
A + + F++ FT A+ + ++ + ++P + + TG+ L Y +
Sbjct 3625 NATDYWTFRKMFTIQLALIGLAEFMLHLNRLNPEMLQIAQDTGK-----LNVSYFRFDIN 3679
Query 61 LAFGD-----RIPFRLTRNIELLIDVFGRAGLLPGCMYTLVCCLQSYSSHFSNAAALLIR 115
A GD +PFRLT NI + G +G L M + C + ++R
Sbjct 3680 DATGDLDANRPVPFRLTPNISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGILKAVLR 3739
Query 116 DDVAFFYRQKQQQQQQLLLLAPAA 139
D++ ++ K+ Q+ + L+PA
Sbjct 3740 DEIIAWH--KKTQEDTSMPLSPAG 3761
> tgo:TGME49_048530 phosphatidylinositol 3- and 4-kinase domain-containing
protein (EC:2.7.11.1); K04728 ataxia telangectasia
mutated family protein [EC:2.7.11.1]
Length=2008
Score = 42.0 bits (97), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 27/89 (30%), Positives = 49/89 (55%), Gaps = 6/89 (6%)
Query 4 ELFVFKRQ-FTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLA 62
+++ KRQ + ++ AV +++Y+ + D N +LLD+ +G + + + LL A
Sbjct 1714 DVWYEKRQRYRRTLAVSSMVSYIIGLGDRHTNNILLDVASGDLIHIDFGVVFEQGKLL-A 1772
Query 63 FGDRIPFRLTRNIELLIDVFGRAGLLPGC 91
+ +PFRLTR+ L+D G G+ GC
Sbjct 1773 IPELVPFRLTRD---LVDGLGCLGVA-GC 1797
> mmu:100683 Trrap, AI481500; transformation/transcription domain-associated
protein; K08874 transformation/transcription
domain-associated protein
Length=3847
Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 28/132 (21%), Positives = 56/132 (42%), Gaps = 10/132 (7%)
Query 1 GAEELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLL 60
A + + F++ FT A+ ++ + ++P + + TG+ L Y +
Sbjct 3649 NATDYWTFRKMFTIQLALIGFAEFVLHLNRLNPEMLQIAQDTGK-----LNVAYFRFDIN 3703
Query 61 LAFGD-----RIPFRLTRNIELLIDVFGRAGLLPGCMYTLVCCLQSYSSHFSNAAALLIR 115
A GD +PFRLT NI + G +G L M + C + ++R
Sbjct 3704 DATGDLDANRPVPFRLTPNISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGVLKTVLR 3763
Query 116 DDVAFFYRQKQQ 127
D++ ++++ Q+
Sbjct 3764 DEIIAWHKKTQE 3775
> hsa:8295 TRRAP, FLJ10671, PAF350/400, PAF400, STAF40, TR-AP,
Tra1; transformation/transcription domain-associated protein;
K08874 transformation/transcription domain-associated protein
Length=3830
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 28/132 (21%), Positives = 56/132 (42%), Gaps = 10/132 (7%)
Query 1 GAEELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLL 60
A + + F++ FT A+ ++ + ++P + + TG+ L Y +
Sbjct 3632 NATDYWTFRKMFTIQLALIGFAEFVLHLNRLNPEMLQIAQDTGK-----LNVAYFRFDIN 3686
Query 61 LAFGD-----RIPFRLTRNIELLIDVFGRAGLLPGCMYTLVCCLQSYSSHFSNAAALLIR 115
A GD +PFRLT NI + G +G L M + C + ++R
Sbjct 3687 DATGDLDANRPVPFRLTPNISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGILKTVLR 3746
Query 116 DDVAFFYRQKQQ 127
D++ ++++ Q+
Sbjct 3747 DEIIAWHKKTQE 3758
> sce:YBR136W MEC1, ESR1, SAD3; Genome integrity checkpoint protein
and PI kinase superfamily member; signal transducer required
for cell cycle arrest and transcriptional responses prompted
by damaged or unreplicated DNA; monitors and participates
in meiotic recombination (EC:2.7.11.1); K02543 cell cycle
checkpoint protein MEC1
Length=2368
Score = 39.3 bits (90), Expect = 0.006, Method: Composition-based stats.
Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Query 6 FVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLAFGD 65
F + + +S+AV ++ ++ + D +LLD+QTG+ L + C L +
Sbjct 2200 FNARNTYARSYAVMAMVGHILGLGDRHCENILLDIQTGKVLHVDFD-CLFEKGKRLPVPE 2258
Query 66 RIPFRLTRNIELLIDVFGRAG 86
+PFRLT N+ + + G G
Sbjct 2259 IVPFRLTPNLLDALGIIGTEG 2279
> xla:398148 atm, Xatm, at1, atdc, tel1, telo1; ataxia telangiectasia
mutated (EC:2.7.11.1); K04728 ataxia telangectasia mutated
family protein [EC:2.7.11.1]
Length=3061
Score = 38.9 bits (89), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 7/110 (6%)
Query 12 FTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLAFGDRIPFRL 71
+T+S A I+ Y+ + D +L+D ++ + + +L + +L + +PFRL
Sbjct 2861 YTRSVATSSIVGYIVGLGDRHVQNILIDEESAELVHIDLGVAFEQGKIL-PTPETVPFRL 2919
Query 72 TRNIELLIDVFGRAGLLPGCMYTLVCCLQSYSSHFSNAAALLIRDDVAFF 121
TR+I +D G G + G CC ++ +N ALL +V +
Sbjct 2920 TRDI---VDGMGITG-VEGVFRR--CCEKTMEVMRNNQEALLTIVEVLLY 2963
> tgo:TGME49_083700 phosphatidylinositol 3- and 4-kinase domain-containing
protein (EC:2.7.11.1)
Length=4496
Score = 37.4 bits (85), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 19/78 (24%), Positives = 35/78 (44%), Gaps = 1/78 (1%)
Query 9 KRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLAFGDRIP 68
++ + + A++ I Y+ + D +LLD G + + C L + +P
Sbjct 4229 RQNYAHTLALWSIFGYIIGLGDRHGENILLDTADGSVMHVDFD-CLLEKGRTLPVPEVVP 4287
Query 69 FRLTRNIELLIDVFGRAG 86
FRLT+N+ + V G G
Sbjct 4288 FRLTQNLVSCLGVTGVEG 4305
> bbo:BBOV_IV009520 23.m05829; phosphatidylinositol 4 kinase (EC:2.7.1.67);
K00888 phosphatidylinositol 4-kinase [EC:2.7.1.67]
Length=1143
Score = 37.4 bits (85), Expect = 0.027, Method: Composition-based stats.
Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Query 2 AEELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLL 61
A+ ++ ++ F +SHA Y I++YL + D +LLD G + + C +
Sbjct 968 AKTIYEARKNFIESHAAYSIISYLLQVRDRHNGNILLD-SDGHVIHIDYGFCLSNTPGNI 1026
Query 62 AFGDRIPFRLTRNIELLIDVFG 83
+F + PF+LT+ +DV G
Sbjct 1027 SF-ETSPFKLTKE---YVDVMG 1044
> cel:C47D12.1 trr-1; TRRAP-like (transcription/transformation
domain-associated protein) family member (trr-1); K08874 transformation/transcription
domain-associated protein
Length=4053
Score = 35.8 bits (81), Expect = 0.076, Method: Composition-based stats.
Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 9/89 (10%)
Query 6 FVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTG----QALQAELKACYCAASL-- 59
+ K+Q S AV + Y + + P+++++ + TG + + E++ SL
Sbjct 3872 YAMKKQLLHSLAVLSTIEYHCNLTPMGPDQMMMTMNTGVLSNPSYRFEIRG---GRSLHD 3928
Query 60 LLAFGDRIPFRLTRNIELLIDVFGRAGLL 88
+ FG +PFRLT N+ +L+ V LL
Sbjct 3929 IQHFGHEVPFRLTPNLSILVGVAQDGDLL 3957
> ath:AT5G40820 ATRAD3; ATRAD3; binding / inositol or phosphatidylinositol
kinase/ phosphotransferase, alcohol group as acceptor
/ protein serine/threonine kinase; K06640 ataxia telangiectasia
and Rad3 related [EC:2.7.11.1]
Length=2702
Score = 34.7 bits (78), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 19/75 (25%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query 12 FTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLAFGDRIPFRL 71
+ + AV+ ++ ++ + D +L D +G + + +C L L + +PFRL
Sbjct 2528 YAHTTAVWSMVGHIVGLGDRHGENILFDSTSGDCVHVDF-SCLFDKGLQLEKPELVPFRL 2586
Query 72 TRNIELLIDVFGRAG 86
T+N +ID G G
Sbjct 2587 TQN---MIDGLGITG 2598
> dre:563201 pi4kb, pik4cb, zgc:152715; phosphatidylinositol 4-kinase,
catalytic, beta (EC:2.7.1.67); K00888 phosphatidylinositol
4-kinase [EC:2.7.1.67]
Length=835
Score = 33.1 bits (74), Expect = 0.41, Method: Composition-based stats.
Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
Query 3 EELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLA 62
EE +R F QS A YC++ YL + D +LLD + G + + ++ L
Sbjct 663 EEFLTAQRNFVQSCAGYCLICYLLQVKDRHNGNILLDSE-GHIIHIDFGFILSSSPRNLG 721
Query 63 FGDRIPFRLTRNIELLIDVFG 83
F + F+LT +DV G
Sbjct 722 F-ETSAFKLTSE---FVDVMG 738
> hsa:651610 serine-protein kinase ATM-like; K04728 ataxia telangectasia
mutated family protein [EC:2.7.11.1]
Length=2934
Score = 33.1 bits (74), Expect = 0.48, Method: Composition-based stats.
Identities = 20/80 (25%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Query 12 FTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLAFGDRIPFRL 71
+T+S A I+ Y+ + D +L++ Q+ + + +L + +L + +PFRL
Sbjct 2730 YTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAF-EQGKILPTPETVPFRL 2788
Query 72 TRNIELLIDVFGRAGLLPGC 91
TR+I + + G G+ C
Sbjct 2789 TRDIVDGMGITGVEGVFRRC 2808
> hsa:472 ATM, AT1, ATA, ATC, ATD, ATDC, ATE, DKFZp781A0353, MGC74674,
TEL1, TELO1; ataxia telangiectasia mutated (EC:2.7.11.1);
K04728 ataxia telangectasia mutated family protein [EC:2.7.11.1]
Length=3056
Score = 33.1 bits (74), Expect = 0.51, Method: Composition-based stats.
Identities = 20/80 (25%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Query 12 FTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLAFGDRIPFRL 71
+T+S A I+ Y+ + D +L++ Q+ + + +L + +L + +PFRL
Sbjct 2852 YTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAF-EQGKILPTPETVPFRL 2910
Query 72 TRNIELLIDVFGRAGLLPGC 91
TR+I + + G G+ C
Sbjct 2911 TRDIVDGMGITGVEGVFRRC 2930
> tpv:TP01_0820 phosphatidylinositol 4-kinase; K00888 phosphatidylinositol
4-kinase [EC:2.7.1.67]
Length=1070
Score = 32.7 bits (73), Expect = 0.56, Method: Composition-based stats.
Identities = 19/65 (29%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Query 9 KRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLAFGDRIP 68
++ F +SHA Y I++YL + D +LLD G + + C L + P
Sbjct 901 RKNFIESHAAYSIVSYLLQVKDRHNGNILLD-PYGHVIHIDYGFCLSNFPGKLISFETSP 959
Query 69 FRLTR 73
F+LT+
Sbjct 960 FKLTK 964
> dre:567770 atr, si:dkey-231j24.1; ataxia telangiectasia and
Rad3 related; K06640 ataxia telangiectasia and Rad3 related
[EC:2.7.11.1]
Length=2643
Score = 32.7 bits (73), Expect = 0.57, Method: Compositional matrix adjust.
Identities = 19/76 (25%), Positives = 34/76 (44%), Gaps = 1/76 (1%)
Query 12 FTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLAFGDRIPFRL 71
+ +S AV ++ Y+ + D +L D TG+ + + C + +PFRL
Sbjct 2456 YCRSTAVMSMVGYILGLGDRHGENILFDSFTGECVHVDFN-CLFNKGETFDVPEVVPFRL 2514
Query 72 TRNIELLIDVFGRAGL 87
T+N+ + G GL
Sbjct 2515 TQNMVHAMGPMGTEGL 2530
> cel:F33H1.4 hypothetical protein
Length=1378
Score = 32.3 bits (72), Expect = 0.68, Method: Composition-based stats.
Identities = 13/34 (38%), Positives = 22/34 (64%), Gaps = 0/34 (0%)
Query 116 DDVAFFYRQKQQQQQQLLLLAPAAAAATRRKPPQ 149
DD + + KQ QQQ+++++ P A TR +PP+
Sbjct 72 DDRSDMDKIKQIQQQKMMIVTPMAQKRTRGRPPR 105
> xla:398197 atr, XATR, frp1, mec1, sckl, sckl1; ataxia telangiectasia
and Rad3 related (EC:2.7.11.1); K06640 ataxia telangiectasia
and Rad3 related [EC:2.7.11.1]
Length=2655
Score = 32.3 bits (72), Expect = 0.74, Method: Compositional matrix adjust.
Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Query 12 FTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLAFGDRIPFRL 71
+ +S AV ++ Y+ + D +L D TG+ + + C + +PFRL
Sbjct 2468 YCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFN-CLFNKGETFEVPEIVPFRL 2526
Query 72 TRNIELLIDVFGRAGL 87
T N+ + G GL
Sbjct 2527 THNMVNGMGPMGTEGL 2542
> xla:444446 pi4kb, MGC83640, PI4K-beta, PI4Kbeta, pik4cb; phosphatidylinositol
4-kinase, catalytic, beta (EC:2.7.1.67); K00888
phosphatidylinositol 4-kinase [EC:2.7.1.67]
Length=804
Score = 32.0 bits (71), Expect = 1.1, Method: Composition-based stats.
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
Query 3 EELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLA 62
E +R F QS A YC++ YL + D +LLD + G + + ++ L
Sbjct 632 EAFLTAQRNFVQSCAAYCLVCYLLQVKDRHNGNILLDAE-GHIIHIDFGFILSSSPRNLG 690
Query 63 FGDRIPFRLTRNIELLIDVFG 83
F + F+LT +DV G
Sbjct 691 F-ETSAFKLTAE---FVDVMG 707
> tgo:TGME49_028690 phosphatidylinositol 3- and 4-kinase domain-containing
protein (EC:2.7.1.67)
Length=6096
Score = 31.6 bits (70), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 20/93 (21%), Positives = 42/93 (45%), Gaps = 3/93 (3%)
Query 10 RQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLAFGDRIPF 69
+ F +S A Y +L+Y+ + D +L+ Q+G+ + + + + ++ PF
Sbjct 5964 KNFVKSLAGYAVLSYILQVKDRHNGNLLISRQSGRVIHIDFGFVFDISPGHDMQFEKAPF 6023
Query 70 RLTRNIELLIDVFGRAGLLPGCMYTLVCCLQSY 102
+LTR + L+ R + Y C+Q +
Sbjct 6024 KLTREMVQLMGGDSRTEMF---RYFTRLCVQGW 6053
> cel:F35H12.4 hypothetical protein; K00888 phosphatidylinositol
4-kinase [EC:2.7.1.67]
Length=666
Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats.
Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 5/75 (6%)
Query 9 KRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLLAFGDRIP 68
++ F QS A Y +++Y + D +LLD+ G + + ++ L F + P
Sbjct 499 QKNFIQSTAAYSLVSYYLQLKDRHNGNILLDMD-GHLIHIDYGFLLSSSPRNLGF-ETAP 556
Query 69 FRLTRNIELLIDVFG 83
F+LT I IDV G
Sbjct 557 FKLTTEI---IDVMG 568
> pfa:PFE0485w phosphatidylinositol 4-kinase, putative (EC:2.7.1.67);
K00888 phosphatidylinositol 4-kinase [EC:2.7.1.67]
Length=1559
Score = 31.2 bits (69), Expect = 1.8, Method: Composition-based stats.
Identities = 13/38 (34%), Positives = 23/38 (60%), Gaps = 0/38 (0%)
Query 2 AEELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLD 39
++ +F K+ F +SHA Y +++YL + D +LLD
Sbjct 1384 SDYIFEAKKNFIESHAAYSLISYLLQVKDRHNGNLLLD 1421
> tgo:TGME49_066000 phosphatidylinositol 3- and 4-kinase domain-containing
protein (EC:2.7.11.1 6.3.1.11)
Length=2138
Score = 30.0 bits (66), Expect = 3.8, Method: Composition-based stats.
Identities = 18/71 (25%), Positives = 31/71 (43%), Gaps = 0/71 (0%)
Query 2 AEELFVFKRQFTQSHAVYCILNYLFCMPDISPNKVLLDLQTGQALQAELKACYCAASLLL 61
A + F+ +R F S A Y+ + D LLD G+ +Q + + ++ L
Sbjct 1573 ASKFFILRRIFATSLAAGSAAGYVLGVGDRHLENWLLDFSRGEVVQIDFGYAFDSSVTEL 1632
Query 62 AFGDRIPFRLT 72
+ PFRL+
Sbjct 1633 PVPELAPFRLS 1643
Lambda K H
0.329 0.139 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 4157683456
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
Posted date: Sep 17, 2011 2:57 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40