bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
164,496 sequences; 82,071,388 total letters
Query= Eten_5087_orf1
Length=128
Score E
Sequences producing significant alignments: (Bits) Value
ath:AT3G10850 GLY2; GLY2; hydroxyacylglutathione hydrolase (EC... 171 5e-43
dre:336977 hagh, fa66a03, wu:fa66a03, zgc:73161; hydroxyacylgl... 169 2e-42
xla:734940 hagh; hydroxyacylglutathione hydrolase (EC:3.1.2.6)... 168 3e-42
mmu:14651 Hagh, BC019817, Glo-2, Glo2, Rsp29; hydroxyacyl glut... 164 7e-41
hsa:3029 HAGH, GLO2, GLX2, GLXII, HAGH1; hydroxyacylglutathion... 162 3e-40
cel:Y17G7B.3 hypothetical protein; K01069 hydroxyacylglutathio... 152 2e-37
tgo:TGME49_081630 hydroxyacylglutathione hydrolase, putative (... 152 2e-37
tpv:TP01_0292 hydroxyacyl glutathione hydrolase; K01069 hydrox... 149 3e-36
bbo:BBOV_IV004560 23.m05978; hydroxyacylglutathione hydrolase ... 147 9e-36
pfa:PFD0311w cGloII; cytosolic glyoxalase II (EC:3.1.2.6); K01... 136 1e-32
mmu:68977 Haghl, 1500017E18Rik, 2810014I23Rik, AI844861, C3300... 134 8e-32
xla:779396 haghl, MGC154399; hydroxyacylglutathione hydrolase-... 133 2e-31
hsa:84264 HAGHL, MGC2605; hydroxyacylglutathione hydrolase-lik... 126 2e-29
dre:497562 pnkd, im:7147352; paroxysmal nonkinesigenic dyskinesia 115 4e-26
mmu:56695 Pnkd, 2210013N15Rik, 2810403H05Rik, AI854243, Brp17,... 114 1e-25
ath:AT1G06130 GLX2-4; GLX2-4 (glyoxalase 2-4); hydrolase/ hydr... 111 6e-25
ath:AT2G31350 GLX2-5; GLX2-5 (GLYOXALASE 2-5); hydroxyacylglut... 110 1e-24
eco:b0212 gloB, ECK0212, JW0202, yafR; hydroxyacylglutathione ... 100 1e-21
ath:AT2G43430 GLX2-1; GLX2-1 (GLYOXALASE 2-1); hydroxyacylglut... 98.2 5e-21
pfa:PFL0285w targeted glyoxalase II (EC:3.2.1.6); K01069 hydro... 91.7 5e-19
sce:YDR272W GLO2; Cytoplasmic glyoxalase II, catalyzes the hyd... 87.0 1e-17
sce:YOR040W GLO4; Glo4p (EC:3.1.2.6); K01069 hydroxyacylglutat... 82.8 3e-16
ath:AT1G53580 GLY3; GLY3 (GLYOXALASE II 3); hydrolase/ hydroxy... 53.5 1e-07
xla:379091 ethe1, MGC53036; ethylmalonic encephalopathy 1 47.4
hsa:23474 ETHE1, HSCO, YF13H12; ethylmalonic encephalopathy 1 44.3
mmu:66071 Ethe1, 0610025L15Rik, Hsco, MGC102424; ethylmalonic ... 44.3 9e-05
cel:C33A12.7 hypothetical protein 42.7 3e-04
dre:405865 ethe1, MGC85680, zgc:85680; ethylmalonic encephalop... 42.7 3e-04
eco:b0927 ycbL, ECK0918, JW0910; predicted metal-binding enzyme 36.6 0.019
xla:398912 gpaa1, MGC68658; glycosylphosphatidylinositol ancho... 29.6 2.2
cel:F14D12.1 hypothetical protein 28.9 3.8
pfa:MAL8P1.60 conserved Plasmodium protein, unknown function 28.1 6.8
hsa:1770 DNAH9, DNAH17L, DNEL1, DYH9, Dnahc9, HL-20, HL20, KIA... 28.1 7.8
dre:560924 dysf, fb73b05, si:rp71-50c18.1, wu:fb73b05; dysferl... 27.7 8.2
> ath:AT3G10850 GLY2; GLY2; hydroxyacylglutathione hydrolase (EC:3.1.2.6);
K01069 hydroxyacylglutathione hydrolase [EC:3.1.2.6]
Length=258
Score = 171 bits (433), Expect = 5e-43, Method: Compositional matrix adjust.
Identities = 78/128 (60%), Positives = 94/128 (73%), Gaps = 2/128 (1%)
Query 1 HAPCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGRFFEGDATQMHRALMKIIGELP 60
H PCHT GH+ YYV + N P +FTGDTLF+AGCG+FFEG A QM+++L + LP
Sbjct 108 HTPCHTKGHISYYVNGKEGEN--PAVFTGDTLFVAGCGKFFEGTAEQMYQSLCVTLAALP 165
Query 61 AETLVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGKPTIPSSIGEEKTYNPF 120
T VYCGHEYTV NL+FA +VEPNN +Q KL WA+QQR A PTIPS++ EE NPF
Sbjct 166 KPTQVYCGHEYTVKNLEFALTVEPNNGKIQQKLAWARQQRQADLPTIPSTLEEELETNPF 225
Query 121 MRVDKPEV 128
MRVDKPE+
Sbjct 226 MRVDKPEI 233
> dre:336977 hagh, fa66a03, wu:fa66a03, zgc:73161; hydroxyacylglutathione
hydrolase (EC:3.1.2.6); K01069 hydroxyacylglutathione
hydrolase [EC:3.1.2.6]
Length=260
Score = 169 bits (427), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 72/126 (57%), Positives = 100/126 (79%), Gaps = 1/126 (0%)
Query 3 PCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGRFFEGDATQMHRALMKIIGELPAE 62
PCHTSGH+ Y+V ++ +S P +FTGDTLF+AGCG+FFEG A +M++AL++++G LP E
Sbjct 108 PCHTSGHICYFV-TKENSTEAPAVFTGDTLFVAGCGKFFEGTADEMYKALIEVLGRLPPE 166
Query 63 TLVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGKPTIPSSIGEEKTYNPFMR 122
T VYCGHEYT+ NL+FA VEPNN ++ KL WA+++ + G+PTIPS++ EE T+NPFMR
Sbjct 167 TRVYCGHEYTINNLKFARHVEPNNEVIRTKLAWAKEKYDNGEPTIPSTVAEEFTFNPFMR 226
Query 123 VDKPEV 128
V + V
Sbjct 227 VREKSV 232
> xla:734940 hagh; hydroxyacylglutathione hydrolase (EC:3.1.2.6);
K01069 hydroxyacylglutathione hydrolase [EC:3.1.2.6]
Length=260
Score = 168 bits (426), Expect = 3e-42, Method: Compositional matrix adjust.
Identities = 74/128 (57%), Positives = 100/128 (78%), Gaps = 1/128 (0%)
Query 1 HAPCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGRFFEGDATQMHRALMKIIGELP 60
+ PCHTSGH+ YYV ++ +S P +FTGDTLF+AGCG+FFEG A +M+ AL++++G LP
Sbjct 106 YTPCHTSGHICYYV-TKPNSTEPPALFTGDTLFVAGCGKFFEGTAEEMYAALIEVLGRLP 164
Query 61 AETLVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGKPTIPSSIGEEKTYNPF 120
+T VYCGHEYT+ NL+FA VEPNN A++ KL WA++ N G+PTIPS++ EE T+NPF
Sbjct 165 PQTRVYCGHEYTINNLKFARHVEPNNDAIKQKLAWAKETYNNGEPTIPSTLAEEFTFNPF 224
Query 121 MRVDKPEV 128
MRV + V
Sbjct 225 MRVREKSV 232
> mmu:14651 Hagh, BC019817, Glo-2, Glo2, Rsp29; hydroxyacyl glutathione
hydrolase (EC:3.1.2.6); K01069 hydroxyacylglutathione
hydrolase [EC:3.1.2.6]
Length=260
Score = 164 bits (414), Expect = 7e-41, Method: Compositional matrix adjust.
Identities = 72/126 (57%), Positives = 98/126 (77%), Gaps = 1/126 (0%)
Query 3 PCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGRFFEGDATQMHRALMKIIGELPAE 62
PCHTSGH+ Y+V S+ S+ +FTGDTLF+AGCG+F+EG A +M++AL++++G LP +
Sbjct 108 PCHTSGHICYFV-SKPGSSEPSAVFTGDTLFVAGCGKFYEGTADEMYKALLEVLGRLPPD 166
Query 63 TLVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGKPTIPSSIGEEKTYNPFMR 122
T VYCGHEYTV NL+FA VEP N A+Q KL WA+++ G+PT+PS++ EE TYNPFMR
Sbjct 167 TKVYCGHEYTVNNLKFARHVEPGNAAIQEKLAWAKEKYAIGEPTVPSTLAEEFTYNPFMR 226
Query 123 VDKPEV 128
V + V
Sbjct 227 VKEKTV 232
> hsa:3029 HAGH, GLO2, GLX2, GLXII, HAGH1; hydroxyacylglutathione
hydrolase (EC:3.1.2.6); K01069 hydroxyacylglutathione hydrolase
[EC:3.1.2.6]
Length=260
Score = 162 bits (409), Expect = 3e-40, Method: Compositional matrix adjust.
Identities = 70/126 (55%), Positives = 98/126 (77%), Gaps = 1/126 (0%)
Query 3 PCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGRFFEGDATQMHRALMKIIGELPAE 62
PCHTSGH+ Y+V S+ + P +FTGDTLF+AGCG+F+EG A +M +AL++++G LP +
Sbjct 108 PCHTSGHICYFV-SKPGGSEPPAVFTGDTLFVAGCGKFYEGTADEMCKALLEVLGRLPPD 166
Query 63 TLVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGKPTIPSSIGEEKTYNPFMR 122
T VYCGHEYT+ NL+FA VEP N A++ KL WA+++ + G+PT+PS++ EE TYNPFMR
Sbjct 167 TRVYCGHEYTINNLKFARHVEPGNAAIREKLAWAKEKYSIGEPTVPSTLAEEFTYNPFMR 226
Query 123 VDKPEV 128
V + V
Sbjct 227 VREKTV 232
> cel:Y17G7B.3 hypothetical protein; K01069 hydroxyacylglutathione
hydrolase [EC:3.1.2.6]
Length=260
Score = 152 bits (385), Expect = 2e-37, Method: Compositional matrix adjust.
Identities = 72/126 (57%), Positives = 90/126 (71%), Gaps = 1/126 (0%)
Query 3 PCHTSGHVLYYVES-RTDSNATPIIFTGDTLFLAGCGRFFEGDATQMHRALMKIIGELPA 61
PCHTSGH+ Y++ + DS + ++FTGDTLF+AGCGRFFEG A QM AL +I+ LP
Sbjct 110 PCHTSGHICYHITNPAADSTSPGVVFTGDTLFIAGCGRFFEGTAPQMDVALNEILKNLPV 169
Query 62 ETLVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGKPTIPSSIGEEKTYNPFM 121
ET ++ GHEYTVANL+FA VEP N KLEWAQ+Q G T+PS++ EEK NPFM
Sbjct 170 ETQIFPGHEYTVANLKFACHVEPGNEKAAQKLEWAQRQIEQGGFTVPSTVAEEKATNPFM 229
Query 122 RVDKPE 127
RV + E
Sbjct 230 RVRESE 235
> tgo:TGME49_081630 hydroxyacylglutathione hydrolase, putative
(EC:3.1.2.6); K01069 hydroxyacylglutathione hydrolase [EC:3.1.2.6]
Length=398
Score = 152 bits (385), Expect = 2e-37, Method: Composition-based stats.
Identities = 76/154 (49%), Positives = 92/154 (59%), Gaps = 26/154 (16%)
Query 1 HAPCHTSGHVLYYV-ESRTDSNATPIIFTG-------------------------DTLFL 34
HAPCHT GHVLY+V S+ PI+FTG DTLF+
Sbjct 221 HAPCHTGGHVLYFVTSSKHPEGKAPILFTGASRRSDGRISFSCCGKRGIQKRAKRDTLFV 280
Query 35 AGCGRFFEGDATQMHRALMKIIGELPAETLVYCGHEYTVANLQFAASVEPNNPAVQNKLE 94
GCGRFFEG A QM AL+ +I LP T VYCGHEYT +NL+FA VEP+N +Q K
Sbjct 281 GGCGRFFEGTAQQMCHALLDVIRSLPKATRVYCGHEYTKSNLEFALKVEPSNKDLQEKYA 340
Query 95 WAQQQRNAGKPTIPSSIGEEKTYNPFMRVDKPEV 128
W +QR A KPT+PSS+ +E YNPFMRV++ V
Sbjct 341 WTVEQRKANKPTVPSSVEQEMRYNPFMRVEEKAV 374
> tpv:TP01_0292 hydroxyacyl glutathione hydrolase; K01069 hydroxyacylglutathione
hydrolase [EC:3.1.2.6]
Length=278
Score = 149 bits (375), Expect = 3e-36, Method: Compositional matrix adjust.
Identities = 65/124 (52%), Positives = 93/124 (75%), Gaps = 2/124 (1%)
Query 2 APCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGRFFEGDATQMHRALMKIIGELPA 61
A CHT GH++YY+ T+ N P++F+GDTLF+ GCGRFFEG+A M ++K + LP
Sbjct 133 ASCHTMGHIMYYIYHPTNPNLQPLLFSGDTLFVCGCGRFFEGNAKSM-LEIVKSVKSLPE 191
Query 62 ETLVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGKPTIPSSIGEEKTYNPFM 121
TL+YCGHEYT+ NLQFA +V+P++ V KL+WA++ + G PT+PS++ EEK YNPF+
Sbjct 192 HTLLYCGHEYTLKNLQFAYTVDPSD-VVLRKLDWAKETISKGLPTVPSTLQEEKLYNPFL 250
Query 122 RVDK 125
RV++
Sbjct 251 RVEE 254
> bbo:BBOV_IV004560 23.m05978; hydroxyacylglutathione hydrolase
(EC:3.1.2.6); K01069 hydroxyacylglutathione hydrolase [EC:3.1.2.6]
Length=319
Score = 147 bits (370), Expect = 9e-36, Method: Compositional matrix adjust.
Identities = 64/122 (52%), Positives = 89/122 (72%), Gaps = 2/122 (1%)
Query 1 HAPCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGRFFEGDATQMHRALMKIIGELP 60
PCHT GH+LYYV + +D P++FTGDT+F+ GCGRFFEG A M +M + +
Sbjct 173 RVPCHTLGHMLYYVTNPSDPTMQPLMFTGDTIFIGGCGRFFEGTADMMLN-IMNTVRQYR 231
Query 61 AETLVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGKPTIPSSIGEEKTYNPF 120
++L+YCGHEYTV NL+FA++V+ ++PAV+ K+EWA+ R PT+PS++GEE YNPF
Sbjct 232 KDSLIYCGHEYTVKNLKFASTVD-DSPAVKRKMEWAESARQQNLPTVPSTLGEELEYNPF 290
Query 121 MR 122
MR
Sbjct 291 MR 292
> pfa:PFD0311w cGloII; cytosolic glyoxalase II (EC:3.1.2.6); K01069
hydroxyacylglutathione hydrolase [EC:3.1.2.6]
Length=263
Score = 136 bits (343), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 63/127 (49%), Positives = 84/127 (66%), Gaps = 6/127 (4%)
Query 1 HAPCHTSGHVLYYV-----ESRTDSNATPIIFTGDTLFLAGCGRFFEGDATQMHRALMKI 55
HAPCHT GH+LYYV + D PI+FTGDTLF+AGCGRFFEG A M + + K+
Sbjct 111 HAPCHTKGHILYYVYKTDEAKQEDHKYKPILFTGDTLFIAGCGRFFEGSAKDMFKNIEKV 170
Query 56 IGELPAETLVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGKPTIPSSIGEEK 115
+ ETL+YCGHEYT+ NL+FA S+E +N ++NKL ++ + ++PS+I EE
Sbjct 171 -KNMRKETLIYCGHEYTLNNLRFALSIENDNEYMKNKLNEVTEKLKNKEHSVPSTIEEEN 229
Query 116 TYNPFMR 122
NPF R
Sbjct 230 LINPFFR 236
> mmu:68977 Haghl, 1500017E18Rik, 2810014I23Rik, AI844861, C330022E15Rik,
MGC101974; hydroxyacylglutathione hydrolase-like
(EC:3.1.2.6); K01069 hydroxyacylglutathione hydrolase [EC:3.1.2.6]
Length=283
Score = 134 bits (337), Expect = 8e-32, Method: Compositional matrix adjust.
Identities = 63/126 (50%), Positives = 87/126 (69%), Gaps = 1/126 (0%)
Query 3 PCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGRFFEGDATQMHRALMKIIGELPAE 62
P HTSGH+ Y++ D +P +F+GD L +AGCG E A QM+++L K +G LP E
Sbjct 108 PGHTSGHMSYFL-WEDDCPDSPALFSGDALSVAGCGWHLEDTAQQMYQSLAKTLGTLPPE 166
Query 63 TLVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGKPTIPSSIGEEKTYNPFMR 122
T V+CGHE+T++NL+FA VEP N VQ KL WAQ++ + PT+PS++GEE YNPF+R
Sbjct 167 TKVFCGHEHTLSNLEFAQKVEPCNEHVQAKLSWAQERDDEDIPTVPSTLGEELMYNPFLR 226
Query 123 VDKPEV 128
V + V
Sbjct 227 VTEDAV 232
> xla:779396 haghl, MGC154399; hydroxyacylglutathione hydrolase-like
(EC:3.1.2.6); K01069 hydroxyacylglutathione hydrolase
[EC:3.1.2.6]
Length=300
Score = 133 bits (334), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 65/138 (47%), Positives = 88/138 (63%), Gaps = 13/138 (9%)
Query 3 PCHTSGHVLYYVESRTDSNATPIIFTGD------------TLFLAGCGRFFEGDATQMHR 50
PCHTSGH+ +++ +A P +F+GD TLF+ GCG F+EG A QM++
Sbjct 108 PCHTSGHMCFFIWEDGCPDA-PALFSGDLLEQLVGQTHRDTLFVGGCGMFYEGTAEQMYK 166
Query 51 ALMKIIGELPAETLVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGKPTIPSS 110
L + +G LP +T V+CGHEYTV NL+FA VEP+N V+ KL WA+ + PT+PSS
Sbjct 167 NLSETLGSLPKDTKVFCGHEYTVRNLKFALKVEPSNEKVKEKLAWAKARDEDDIPTVPSS 226
Query 111 IGEEKTYNPFMRVDKPEV 128
+ EE YNPFMRV + V
Sbjct 227 LEEEFLYNPFMRVREEAV 244
> hsa:84264 HAGHL, MGC2605; hydroxyacylglutathione hydrolase-like
(EC:3.1.2.6); K01069 hydroxyacylglutathione hydrolase [EC:3.1.2.6]
Length=282
Score = 126 bits (316), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 59/121 (48%), Positives = 85/121 (70%), Gaps = 2/121 (1%)
Query 3 PCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGRFFEGDATQMHRALMKIIGELPAE 62
P HT+GH+ Y++ D P +F+GD L +AGCG EG A QM+++L ++ G LP E
Sbjct 108 PGHTAGHMSYFL-WEDDCPDPPALFSGDALSVAGCGSCLEGSAQQMYQSLAEL-GTLPPE 165
Query 63 TLVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGKPTIPSSIGEEKTYNPFMR 122
T V+CGHE+T++NL+FA VEP N V+ KL WA+++ PT+PS++GEE+ YNPF+R
Sbjct 166 TKVFCGHEHTLSNLEFAQKVEPCNDHVRAKLSWAKKRDEDDVPTVPSTLGEERLYNPFLR 225
Query 123 V 123
V
Sbjct 226 V 226
> dre:497562 pnkd, im:7147352; paroxysmal nonkinesigenic dyskinesia
Length=361
Score = 115 bits (288), Expect = 4e-26, Method: Compositional matrix adjust.
Identities = 56/122 (45%), Positives = 79/122 (64%), Gaps = 2/122 (1%)
Query 1 HAPCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGRFFEGDATQMHRALMKIIGELP 60
+ P HT GH++Y ++ R + + F+GD +FL+GCGR FEG+A+ M +L +G L
Sbjct 201 YTPGHTVGHMIYLLDGRAIGGPSSL-FSGDLVFLSGCGRMFEGNASTMLSSL-DTVGSLN 258
Query 61 AETLVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGKPTIPSSIGEEKTYNPF 120
+TL++ GHEY NL FAA VEP N + KL+W QQR+ T PS++ EEK YNPF
Sbjct 259 DDTLLWPGHEYAEDNLLFAADVEPGNVVREQKLQWVLQQRSQRLCTCPSTLLEEKQYNPF 318
Query 121 MR 122
+R
Sbjct 319 LR 320
> mmu:56695 Pnkd, 2210013N15Rik, 2810403H05Rik, AI854243, Brp17,
MNCb-5687, MR-1, Tahccp2; paroxysmal nonkinesiogenic dyskinesia
Length=385
Score = 114 bits (284), Expect = 1e-25, Method: Compositional matrix adjust.
Identities = 55/121 (45%), Positives = 78/121 (64%), Gaps = 2/121 (1%)
Query 3 PCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGRFFEGDATQMHRALMKIIGELPAE 62
P HT GH++Y ++ + +F+GD LFL+GCGR FEG A M +L ++ +L +
Sbjct 227 PGHTQGHLVYLLDGEPYKGPS-CLFSGDLLFLSGCGRTFEGTAETMLSSLDTVL-DLGDD 284
Query 63 TLVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGKPTIPSSIGEEKTYNPFMR 122
TL++ GHEY NL FA VEP N A + K++W Q+QR K T PS++GEE+ YNPF+R
Sbjct 285 TLLWPGHEYAEENLGFAGVVEPENLARERKMQWVQRQRMERKSTCPSTLGEERAYNPFLR 344
Query 123 V 123
Sbjct 345 T 345
> ath:AT1G06130 GLX2-4; GLX2-4 (glyoxalase 2-4); hydrolase/ hydroxyacylglutathione
hydrolase/ zinc ion binding (EC:3.1.2.6)
Length=331
Score = 111 bits (277), Expect = 6e-25, Method: Compositional matrix adjust.
Identities = 54/126 (42%), Positives = 76/126 (60%), Gaps = 7/126 (5%)
Query 3 PCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGRFFEGDATQMHRALMKIIGELPAE 62
P HT GH+ +Y IFTGDTLF CG+ FEG QM +L +II LP +
Sbjct 185 PGHTRGHISFYFP------GARAIFTGDTLFSLSCGKLFEGTPEQMLASLQRIIA-LPDD 237
Query 63 TLVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGKPTIPSSIGEEKTYNPFMR 122
T VYCGHEYT++N +FA S+EP N +Q+ + + R+ PTIP+++ EK NPF+R
Sbjct 238 TSVYCGHEYTLSNSKFALSIEPTNEVLQSYAAYVAELRDKKLPTIPTTMKMEKACNPFLR 297
Query 123 VDKPEV 128
+ ++
Sbjct 298 TENTDI 303
> ath:AT2G31350 GLX2-5; GLX2-5 (GLYOXALASE 2-5); hydroxyacylglutathione
hydrolase/ iron ion binding / zinc ion binding (EC:3.1.2.6)
Length=324
Score = 110 bits (274), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 56/127 (44%), Positives = 77/127 (60%), Gaps = 9/127 (7%)
Query 3 PCHTSGHV-LYYVESRTDSNATPIIFTGDTLFLAGCGRFFEGDATQMHRALMKIIGELPA 61
P HT GH+ LY+ SR IFTGDT+F CG+ FEG QM +L KI LP
Sbjct 180 PGHTKGHISLYFPGSRA-------IFTGDTMFSLSCGKLFEGTPKQMLASLQKITS-LPD 231
Query 62 ETLVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGKPTIPSSIGEEKTYNPFM 121
+T +YCGHEYT++N +FA S+EPNN +Q+ + R+ PTIP+++ EK NPF+
Sbjct 232 DTSIYCGHEYTLSNSKFALSLEPNNEVLQSYAAHVAELRSKKLPTIPTTVKMEKACNPFL 291
Query 122 RVDKPEV 128
R ++
Sbjct 292 RSSNTDI 298
> eco:b0212 gloB, ECK0212, JW0202, yafR; hydroxyacylglutathione
hydrolase; K01069 hydroxyacylglutathione hydrolase [EC:3.1.2.6]
Length=251
Score = 100 bits (249), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 47/126 (37%), Positives = 77/126 (61%), Gaps = 9/126 (7%)
Query 3 PCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGRFFEGDATQMHRALMKIIGELPAE 62
P HT GH+ Y+ + P +F GDTLF GCGR FEG A+QM+++L K+ LP +
Sbjct 108 PGHTLGHICYF--------SKPYLFCGDTLFSGGCGRLFEGTASQMYQSLKKL-SALPDD 158
Query 63 TLVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGKPTIPSSIGEEKTYNPFMR 122
TLV C HEYT++N++FA S+ P++ ++ + ++ R + T+P + E+ N F+R
Sbjct 159 TLVCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLR 218
Query 123 VDKPEV 128
+ ++
Sbjct 219 TEDIDL 224
> ath:AT2G43430 GLX2-1; GLX2-1 (GLYOXALASE 2-1); hydroxyacylglutathione
hydrolase (EC:3.1.2.6)
Length=331
Score = 98.2 bits (243), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 49/126 (38%), Positives = 70/126 (55%), Gaps = 7/126 (5%)
Query 3 PCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGRFFEGDATQMHRALMKIIGELPAE 62
P HT GH+ +Y + IFTGD ++ CG EG QM +L KI+ LP +
Sbjct 187 PGHTQGHISFYFP------GSATIFTGDLIYSLSCGTLSEGTPEQMLSSLQKIV-SLPDD 239
Query 63 TLVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGKPTIPSSIGEEKTYNPFMR 122
T +YCG E T NL+FA SVEP N +Q+ R+ G P+IP+++ EK NPF+R
Sbjct 240 TNIYCGRENTAGNLKFALSVEPKNETLQSYATRVAHLRSQGLPSIPTTVKVEKACNPFLR 299
Query 123 VDKPEV 128
+ ++
Sbjct 300 ISSKDI 305
> pfa:PFL0285w targeted glyoxalase II (EC:3.2.1.6); K01069 hydroxyacylglutathione
hydrolase [EC:3.1.2.6]; K01180 endo-1,3(4)-beta-glucanase
[EC:3.2.1.6]
Length=322
Score = 91.7 bits (226), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 44/126 (34%), Positives = 72/126 (57%), Gaps = 5/126 (3%)
Query 5 HTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGRFFEGDATQMHRALMKIIGELPAETL 64
H+ V Y +E+ + + I FTGD LF++G G+ FE D ++ ++ K+
Sbjct 165 HSKNQVSYLIENDNNKSKKNIFFTGDFLFISGIGKNFEQDNEDLYNSINKLKLLDKQNIY 224
Query 65 VYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGK--PTIPSSIGEEKTYNPFMR 122
++CGHEYT+ NL+FA +V+ N +N L + N+ K PT+P+ + E YNPF+R
Sbjct 225 IFCGHEYTLDNLKFALTVDSTN---KNLLSFYDHVVNSNKNYPTVPTLLEHEYLYNPFLR 281
Query 123 VDKPEV 128
D+ +V
Sbjct 282 CDQNDV 287
> sce:YDR272W GLO2; Cytoplasmic glyoxalase II, catalyzes the hydrolysis
of S-D-lactoylglutathione into glutathione and D-lactate
(EC:3.1.2.6); K01069 hydroxyacylglutathione hydrolase
[EC:3.1.2.6]
Length=274
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 54/137 (39%), Positives = 75/137 (54%), Gaps = 15/137 (10%)
Query 1 HAPCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGRFFEGDATQMHRALMKIIGELP 60
PCHT + YYV+ T IFTGDTLF AGCGRFFEG +M AL I E
Sbjct 117 RTPCHTRDSICYYVKDPTTDERC--IFTGDTLFTAGCGRFFEGTGEEMDIALNNSILETV 174
Query 61 -----AETLVYCGHEYTVANLQFAASVEPN---NPAVQNKLEW-AQQQRNAGKPTIPSSI 111
++T VY GHEYT N++F + P N A+ ++ ++ + AG+ T+
Sbjct 175 GRQNWSKTRVYPGHEYTSDNVKFVRKIYPQVGENKALDELEQFCSKHEVTAGRFTLK--- 231
Query 112 GEEKTYNPFMRVDKPEV 128
+E +NPFMR++ P+V
Sbjct 232 -DEVEFNPFMRLEDPKV 247
> sce:YOR040W GLO4; Glo4p (EC:3.1.2.6); K01069 hydroxyacylglutathione
hydrolase [EC:3.1.2.6]
Length=285
Score = 82.8 bits (203), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 48/132 (36%), Positives = 68/132 (51%), Gaps = 8/132 (6%)
Query 3 PCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGRFFEGDATQMHRALMKIIGELPAE 62
PCHT + YY++ IFTGDTLF+AGCGRFFEG M AL +I+ E
Sbjct 129 PCHTKDSICYYIKDL--ETGEQCIFTGDTLFIAGCGRFFEGTGRDMDMALNQIMLRAVGE 186
Query 63 T-----LVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGKPTIPS-SIGEEKT 116
T +Y GHEYT N+ F + ++ + + +Q + + T ++ +E
Sbjct 187 TNWNKVKIYPGHEYTKGNVSFIRAKIYSDIGQNKEFDALEQYCKSNECTTGHFTLRDELG 246
Query 117 YNPFMRVDKPEV 128
YNPFMR+D V
Sbjct 247 YNPFMRLDDRAV 258
> ath:AT1G53580 GLY3; GLY3 (GLYOXALASE II 3); hydrolase/ hydroxyacylglutathione
hydrolase (EC:3.1.2.6)
Length=294
Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 27/71 (38%), Positives = 39/71 (54%), Gaps = 2/71 (2%)
Query 3 PCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGR--FFEGDATQMHRALMKIIGELP 60
P HT+G V Y D + FTGD + + GCGR F EG + Q++ ++ I LP
Sbjct 164 PGHTAGCVTYVTGEGADQPQPRMAFTGDAVLIRGCGRTDFQEGSSDQLYESVHSQIFTLP 223
Query 61 AETLVYCGHEY 71
+TL+Y H+Y
Sbjct 224 KDTLIYPAHDY 234
> xla:379091 ethe1, MGC53036; ethylmalonic encephalopathy 1
Length=255
Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 30/106 (28%), Positives = 51/106 (48%), Gaps = 9/106 (8%)
Query 3 PCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGR--FFEGDATQMHRALMKIIGELP 60
P HT G + Y + ++ + FTGD L + GCGR F +G ++ ++ I LP
Sbjct 136 PGHTDGCLTYVLNDKS------MAFTGDALLIRGCGRTDFQQGCPKTLYHSVHSKIFSLP 189
Query 61 AETLVYCGHEYTVANLQFAASVEPNNPAV-QNKLEWAQQQRNAGKP 105
L+Y GH+YT + + NP + +++ E+ + N P
Sbjct 190 GNCLLYPGHDYTGQTVSSVEEEKRLNPRLTKDEAEFVKIMNNLNLP 235
> hsa:23474 ETHE1, HSCO, YF13H12; ethylmalonic encephalopathy
1
Length=254
Score = 44.3 bits (103), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 11/89 (12%)
Query 2 APCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGR--FFEGDATQMHRALMKIIGEL 59
+P HT G V + + N + FTGD L + GCGR F +G A ++ ++ + I L
Sbjct 132 SPGHTPGCVTFVL------NDHSMAFTGDALLIRGCGRTDFQQGCAKTLYHSVHEKIFTL 185
Query 60 PAETLVYCGHEY---TVANLQFAASVEPN 85
P + L+Y H+Y TV+ ++ ++ P
Sbjct 186 PGDCLIYPAHDYHGFTVSTVEEERTLNPR 214
> mmu:66071 Ethe1, 0610025L15Rik, Hsco, MGC102424; ethylmalonic
encephalopathy 1
Length=254
Score = 44.3 bits (103), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 28/89 (31%), Positives = 46/89 (51%), Gaps = 11/89 (12%)
Query 2 APCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGR--FFEGDATQMHRALMKIIGEL 59
+P HT G V + + N + FTGD L + GCGR F +G A ++ ++ + I L
Sbjct 132 SPGHTPGCVTFVL------NDQSMAFTGDALLIRGCGRTDFQQGCAKTLYHSVHEKIFTL 185
Query 60 PAETLVYCGHEY---TVANLQFAASVEPN 85
P L+Y H+Y TV+ ++ ++ P
Sbjct 186 PGNCLIYPAHDYHGLTVSTVEEERTLNPR 214
> cel:C33A12.7 hypothetical protein
Length=237
Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 35/103 (33%), Positives = 51/103 (49%), Gaps = 11/103 (10%)
Query 3 PCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGR--FFEGDATQMHRALMKIIGELP 60
P HT+G L YVE S FTGD L + CGR F +G+ + ++ I LP
Sbjct 119 PGHTNG-CLTYVEHSLRS-----AFTGDALLIRACGRTDFQQGNPASLFDSVHDKIFTLP 172
Query 61 AETLVYCGHEYTVANLQFAASVEPN-NPAV-QNKLEWAQQQRN 101
+ +VY GH Y LQ E N NP + ++K ++ + +N
Sbjct 173 EDYVVYVGHNYN-GVLQTTVWEEKNLNPRLTKSKDQFVEIMKN 214
> dre:405865 ethe1, MGC85680, zgc:85680; ethylmalonic encephalopathy
1
Length=279
Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 26/94 (27%), Positives = 42/94 (44%), Gaps = 8/94 (8%)
Query 3 PCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGR--FFEGDATQMHRALMKIIGELP 60
P HT G V Y + + FTGD L + GCGR F +G +++ ++ + I LP
Sbjct 160 PGHTDGCVTYVTGDQR------MAFTGDALLIRGCGRTDFQQGSPHRLYESVHQKIFSLP 213
Query 61 AETLVYCGHEYTVANLQFAASVEPNNPAVQNKLE 94
+Y H+Y + + NP + +E
Sbjct 214 GHCFIYPAHDYKGQTVSTVDEEKKFNPRLTKTVE 247
> eco:b0927 ycbL, ECK0918, JW0910; predicted metal-binding enzyme
Length=215
Score = 36.6 bits (83), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 24/95 (25%), Positives = 43/95 (45%), Gaps = 12/95 (12%)
Query 1 HAPCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGR--FFEGDATQMHRALMKIIGE 58
H P HT GHV+++ + ++ +GD +F G GR F GD Q+ ++ +
Sbjct 128 HCPGHTPGHVVFF------DDRAKLLISGDVIFKGGVGRSDFPRGDHNQLISSIKDKLLP 181
Query 59 LPAETLVYCGHEYTVANLQFAASVEPNNPAVQNKL 93
L + + GH L +NP +Q+++
Sbjct 182 LGDDVIFIPGH----GPLSTLGYERLHNPFLQDEM 212
> xla:398912 gpaa1, MGC68658; glycosylphosphatidylinositol anchor
attachment protein 1 homolog; K05289 glycosylphosphatidylinositol
transamidase
Length=615
Score = 29.6 bits (65), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 26/107 (24%), Positives = 42/107 (39%), Gaps = 23/107 (21%)
Query 4 CHTSGHVLYYV-----ESRTD----SNATPIIFTGDTLFLAGCG------RFFEGDATQM 48
CH +G LYY+ E TD S + ++ T +++AG R G ++
Sbjct 428 CHATGLSLYYLPVMSQEMATDHFPVSESEAVVLTAIAIYVAGLALPHNTHRVLTGAGSEQ 487
Query 49 HRALMKIIGELPAETLVYC--------GHEYTVANLQFAASVEPNNP 87
+K+I L L+ C G + + AA V+P P
Sbjct 488 GWMTLKLISLLYLAVLLGCISLINFSLGFLLAITIVPVAAIVQPTGP 534
> cel:F14D12.1 hypothetical protein
Length=713
Score = 28.9 bits (63), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 13/42 (30%), Positives = 23/42 (54%), Gaps = 3/42 (7%)
Query 48 MHRALMKIIGELPAETLVYC---GHEYTVANLQFAASVEPNN 86
+H + + I+ PAETL+YC G T ++ ++ PN+
Sbjct 27 LHDSRLAIVHGYPAETLLYCEVAGASITTDHMNHRVTITPND 68
> pfa:MAL8P1.60 conserved Plasmodium protein, unknown function
Length=1408
Score = 28.1 bits (61), Expect = 6.8, Method: Composition-based stats.
Identities = 13/39 (33%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Query 2 APCHTSGHVLYYVESRTDSNATPIIFTGDTLFLAGCGRF 40
+PCHT ++L Y+ES N P+ LF+ C ++
Sbjct 1147 SPCHTDNYILNYIES--SENKIPLKDKYMLLFIIYCLKY 1183
> hsa:1770 DNAH9, DNAH17L, DNEL1, DYH9, Dnahc9, HL-20, HL20, KIAA0357;
dynein, axonemal, heavy chain 9
Length=4486
Score = 28.1 bits (61), Expect = 7.8, Method: Compositional matrix adjust.
Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 2/59 (3%)
Query 44 DATQMHRALMKIIG-ELPAETLVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRN 101
D + + L+++ +L A ++Y H A L F+ V N P V L WAQ+ R
Sbjct 562 DTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSP-VHKNMPTVAGGLRWAQELRQ 619
> dre:560924 dysf, fb73b05, si:rp71-50c18.1, wu:fb73b05; dysferlin,
limb girdle muscular dystrophy 2B (autosomal recessive)
Length=1920
Score = 27.7 bits (60), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 19/76 (25%), Positives = 34/76 (44%), Gaps = 6/76 (7%)
Query 48 MHRALMKIIGELPA---ETLVYCGHEYTVANLQFAASVEPNNPAVQNKLEWAQQQRNAGK 104
+HR + +LP + + + GHEYTVA+L + P+ V +L +R+
Sbjct 1537 LHRLCERRNYKLPVYKQDRIYFRGHEYTVADLDEGKPLNPHLGPVMERLALLVLRRHG-- 1594
Query 105 PTIPSSIGEEKTYNPF 120
+P + Y+P
Sbjct 1595 -LVPEHVETRPLYSPL 1609
Lambda K H
0.317 0.133 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 2049573556
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
Posted date: Sep 17, 2011 2:57 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40