bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
164,496 sequences; 82,071,388 total letters
Query= Eten_3362_orf1
Length=153
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_109730 thioredoxin reductase, putative (EC:1.8.1.7)... 145 7e-35
pfa:PFI1170c thioredoxin reductase (EC:1.8.1.9); K00384 thiore... 140 1e-33
xla:447484 txnrd3, MGC81848; thioredoxin reductase 3 (EC:1.8.1... 130 2e-30
dre:798259 im:7135991; si:ch1073-179p4.3 129 4e-30
dre:352924 txnrd1, TrxR1, cb682, fb83a08, wu:fb83a08; thioredo... 126 2e-29
bbo:BBOV_I002190 19.m02214; thiodoxin reductase (EC:1.8.1.9); ... 125 5e-29
cpv:cgd2_4320 thioredoxin reductase 1 ; K00384 thioredoxin red... 124 2e-28
mmu:26462 Txnrd2, AA118373, ESTM573010, TGR, Tr3, Trxr2, Trxrd... 117 2e-26
xla:447610 txnrd1, MGC85342; thioredoxin reductase 1 (EC:1.8.1... 116 3e-26
xla:379744 txnrd2, MGC69182; thioredoxin reductase 2 (EC:1.8.1... 115 6e-26
tpv:TP03_0110 thioredoxin reductase (EC:1.6.4.5); K00384 thior... 107 2e-23
hsa:10587 TXNRD2, SELZ, TR, TR-BETA, TR3, TRXR2; thioredoxin r... 103 3e-22
mmu:232223 Txnrd3, AI196535, TR2, Tgr; thioredoxin reductase 3... 103 3e-22
cel:C06G3.7 trxr-1; ThioRedoXin Reductase family member (trxr-... 102 6e-22
mmu:50493 Txnrd1, TR, TR1, TrxR1; thioredoxin reductase 1 (EC:... 102 7e-22
hsa:7296 TXNRD1, GRIM-12, MGC9145, TR, TR1, TRXR1, TXNR; thior... 101 9e-22
hsa:114112 TXNRD3, TGR, TR2, TRXR3; thioredoxin reductase 3 (E... 101 1e-21
cel:ZK637.10 trxr-2; ThioRedoXin Reductase family member (trxr... 100 2e-21
tgo:TGME49_046920 glutathione reductase, putative (EC:1.8.1.7)... 74.7 1e-13
ath:AT3G24170 ATGR1; ATGR1 (glutathione-disulfide reductase); ... 65.5 6e-11
hsa:2936 GSR, MGC78522; glutathione reductase (EC:1.8.1.7); K0... 64.3 1e-10
ath:AT3G54660 GR; GR (GLUTATHIONE REDUCTASE); ATP binding / gl... 63.9 2e-10
xla:734372 gsr, MGC84926; glutathione reductase (EC:1.8.1.7); ... 58.2 1e-08
sce:YPL091W GLR1, LPG17; Cytosolic and mitochondrial glutathio... 57.8 1e-08
eco:b3500 gor, ECK3485, gorA, JW3467; glutathione oxidoreducta... 57.4 2e-08
mmu:14782 Gsr, AI325518, D8Ertd238e, Gr-1, Gr1; glutathione re... 57.4 2e-08
cel:C46F11.2 hypothetical protein 57.4 2e-08
cel:LLC1.3 hypothetical protein; K00382 dihydrolipoamide dehyd... 55.1 1e-07
bbo:BBOV_IV007190 23.m05858; dihydrolipoamide dehydrogenase (E... 51.6 1e-06
dre:100332932 glutathione reductase-like 51.2 1e-06
dre:553575 MGC110010; zgc:110010 (EC:1.8.1.7); K00383 glutathi... 49.3 5e-06
tpv:TP03_0227 dihydrolipoamide dehydrogenase (EC:1.8.1.4); K00... 47.4 2e-05
sce:YFL018C LPD1, HPD1; Dihydrolipoamide dehydrogenase, the li... 45.8 5e-05
pfa:PF08_0066 lipoamide dehydrogenase, putative (EC:1.8.1.4); ... 45.1 9e-05
hsa:1738 DLD, DLDH, E3, GCSL, LAD, PHE3; dihydrolipoamide dehy... 44.3 1e-04
dre:399479 dldh, wu:fb24b05; dihydrolipoamide dehydrogenase (E... 43.5 3e-04
pfa:PF14_0192 glutathione reductase (EC:1.8.1.7); K00383 gluta... 42.4 5e-04
xla:380588 dld, MGC68940; dihydrolipoamide dehydrogenase (EC:1... 42.0 8e-04
mmu:13382 Dld, AI315664, AI746344; dihydrolipoamide dehydrogen... 41.6 0.001
eco:b0116 lpd, dhl, ECK0115, JW0112, lpdA; lipoamide dehydroge... 40.8 0.002
eco:b3962 sthA, ECK3954, JW5551, sth, udhA; pyridine nucleotid... 40.0 0.003
eco:b0304 ykgC, ECK0303, JW5040; predicted pyridine nucleotide... 38.1 0.010
ath:AT3G17240 mtLPD2; mtLPD2 (LIPOAMIDE DEHYDROGENASE 2); ATP ... 38.1 0.011
ath:AT1G48030 mtLPD1; mtLPD1 (mitochondrial lipoamide dehydrog... 35.4 0.067
ath:AT1G06820 CRTISO; CRTISO (CAROTENOID ISOMERASE); carotenoi... 33.9 0.20
pfa:PFL1550w lipoamide dehydrogenase (EC:1.8.1.4); K00382 dihy... 33.5 0.27
mmu:67442 Retsat, 0610039N19Rik, C80029, MGC143538, MMT-7, Pps... 33.1 0.38
dre:677660 retsatl, wu:fi35b01, zgc:123334; retinol saturase (... 32.3 0.68
mmu:666752 Gm8273, EG666752; predicted gene 8273 31.6
tgo:TGME49_006470 dihydrolipoyl dehydrogenase, putative (EC:1.... 31.6 1.0
> tgo:TGME49_109730 thioredoxin reductase, putative (EC:1.8.1.7);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=662
Score = 145 bits (365), Expect = 7e-35, Method: Compositional matrix adjust.
Identities = 74/146 (50%), Positives = 89/146 (60%), Gaps = 12/146 (8%)
Query 6 KFDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKL 65
+FDYD VIGGGSGGLA K AA GA +V DFV+PS +G +WGLGGTCVNVGC+PK L
Sbjct 157 EFDYDLAVIGGGSGGLACAKMAAAQGAETVVFDFVQPSTQGSTWGLGGTCVNVGCVPKYL 216
Query 66 LHFAAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQLNFSY 125
H W+ P +G + G E Q+ DW VE+VQ+YIK LNF Y
Sbjct 217 FHHTGLAGANAHWDGPHMG---------WKGKFEEQV---DWGVCVEKVQNYIKSLNFGY 264
Query 126 RVGLQNAGCTYTRALARLVGPHTVEY 151
R GL+ AG TY A A+ V PH + Y
Sbjct 265 RTGLRKAGVTYINAYAKFVSPHELAY 290
> pfa:PFI1170c thioredoxin reductase (EC:1.8.1.9); K00384 thioredoxin
reductase (NADPH) [EC:1.8.1.9]
Length=617
Score = 140 bits (354), Expect = 1e-33, Method: Composition-based stats.
Identities = 71/145 (48%), Positives = 92/145 (63%), Gaps = 13/145 (8%)
Query 7 FDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKLL 66
+DYDY+VIGGG GG+AS K+AA GARVL+ D+VKPS +G WG+GGTCVNVGC+PKKL+
Sbjct 116 YDYDYVVIGGGPGGMASAKEAAAHGARVLLFDYVKPSSQGTKWGIGGTCVNVGCVPKKLM 175
Query 67 HFAAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQLNFSYR 126
H+A L Y G+ + LK DW+ LV VQS+I+ LNFSY
Sbjct 176 HYAGHMGSIF-----KLDSKAY-------GWKFDNLKH-DWKKLVTTVQSHIRSLNFSYM 222
Query 127 VGLQNAGCTYTRALARLVGPHTVEY 151
GL+++ Y LA+L +TV Y
Sbjct 223 TGLRSSKVKYINGLAKLKDKNTVSY 247
> xla:447484 txnrd3, MGC81848; thioredoxin reductase 3 (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=596
Score = 130 bits (326), Expect = 2e-30, Method: Compositional matrix adjust.
Identities = 72/157 (45%), Positives = 94/157 (59%), Gaps = 27/157 (17%)
Query 1 DGSTEKFDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGC 60
D ++ +DYD IVIGGGSGGLA K+AA G +V+VLDFV P+ +G SWGLGGTCVNVGC
Sbjct 104 DDNSVTYDYDLIVIGGGSGGLACSKEAASFGKKVMVLDFVVPTPQGTSWGLGGTCVNVGC 163
Query 61 IPKKLLHFAA-------QTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVER 113
IPKKL+H AA +R+FG WE E Q+K +W+T+ E
Sbjct 164 IPKKLMHQAAILGQSLKDSRKFG-WEY------------------EEQVKH-NWETMREA 203
Query 114 VQSYIKQLNFSYRVGLQNAGCTYTRALARLVGPHTVE 150
+Q+YI LN+ YRV L++ Y A V H ++
Sbjct 204 IQNYIGSLNWGYRVALRDKQVRYENAYGEFVESHKIK 240
> dre:798259 im:7135991; si:ch1073-179p4.3
Length=371
Score = 129 bits (324), Expect = 4e-30, Method: Compositional matrix adjust.
Identities = 69/152 (45%), Positives = 90/152 (59%), Gaps = 27/152 (17%)
Query 6 KFDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKL 65
KFDYD +VIGGGSGGLA K+AA LG +V VLD+V+PS++G WGLGGTCVNVGCIPKKL
Sbjct 30 KFDYDLVVIGGGSGGLACSKEAAQLGQKVAVLDYVEPSLKGTKWGLGGTCVNVGCIPKKL 89
Query 66 LHFAA-------QTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYI 118
+H AA R++G W+ P + DW T+ E VQ+++
Sbjct 90 MHQAALLGTAVKDARKYG-WQIP-------------------ETLSHDWPTMAEAVQNHV 129
Query 119 KQLNFSYRVGLQNAGCTYTRALARLVGPHTVE 150
+ LN+ +RV LQ+ Y L+ HTV
Sbjct 130 RSLNWGHRVQLQDKKVKYLNMKGTLLDKHTVR 161
> dre:352924 txnrd1, TrxR1, cb682, fb83a08, wu:fb83a08; thioredoxin
reductase 1 (EC:1.8.1.9); K00384 thioredoxin reductase
(NADPH) [EC:1.8.1.9]
Length=602
Score = 126 bits (317), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 70/154 (45%), Positives = 90/154 (58%), Gaps = 27/154 (17%)
Query 4 TEKFDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPK 63
+E +DYD IVIGGGSGGLA K+AA LG +V+VLD+V P+ +G +WGLGGTCVNVGCIPK
Sbjct 111 SEVYDYDLIVIGGGSGGLACSKEAATLGKKVMVLDYVVPTPQGTAWGLGGTCVNVGCIPK 170
Query 64 KLLHFAA-------QTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQS 116
KL+H A R+FG WE F E +W+T+ V +
Sbjct 171 KLMHQTALLGTAMEDARKFG-WE-----------------FAEQVTH--NWETMKTAVNN 210
Query 117 YIKQLNFSYRVGLQNAGCTYTRALARLVGPHTVE 150
YI LN+ YRV L++ Y A A V PH ++
Sbjct 211 YIGSLNWGYRVSLRDKNVNYVNAYAEFVEPHKIK 244
> bbo:BBOV_I002190 19.m02214; thiodoxin reductase (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=559
Score = 125 bits (315), Expect = 5e-29, Method: Compositional matrix adjust.
Identities = 68/149 (45%), Positives = 87/149 (58%), Gaps = 14/149 (9%)
Query 3 STEKFDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIP 62
S E YD VIGGG GLA+ K+AA LGA+ ++ D+V+PS RG WGLGGTCVNVGCIP
Sbjct 63 SVEPELYDLAVIGGGCSGLAAAKEAARLGAKTVLFDYVRPSPRGTKWGLGGTCVNVGCIP 122
Query 63 KKLLHFAAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQLN 122
KKL+H+A + MLG + P++ DW +++ +Q+Y+K LN
Sbjct 123 KKLMHYAG-ILGHAEHDREMLGWS--------DASPKH-----DWSKMIQTIQNYVKMLN 168
Query 123 FSYRVGLQNAGCTYTRALARLVGPHTVEY 151
FSYR GL G Y A A L H V Y
Sbjct 169 FSYRSGLLTTGVKYINAFATLEKDHQVSY 197
> cpv:cgd2_4320 thioredoxin reductase 1 ; K00384 thioredoxin reductase
(NADPH) [EC:1.8.1.9]
Length=526
Score = 124 bits (310), Expect = 2e-28, Method: Composition-based stats.
Identities = 69/147 (46%), Positives = 93/147 (63%), Gaps = 14/147 (9%)
Query 7 FDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKLL 66
F YD +VIGGGSGG+A+ K+AA G +V + DFVKPS +G WGLGGTCVNVGC+PKKL+
Sbjct 31 FMYDLVVIGGGSGGMAAAKEAAKYGKKVALFDFVKPSTQGTKWGLGGTCVNVGCVPKKLM 90
Query 67 HFAAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQLNFSYR 126
H++A +A M G + +W LVE ++++I+ LNFSYR
Sbjct 91 HYSALIASSIHHDAQMFGHKTSSSF--------------EWGKLVETLRNHIRMLNFSYR 136
Query 127 VGLQNAGCTYTRALARLVGPHTVEYEE 153
GL+ Y ALA+L+ PH+VEYE+
Sbjct 137 TGLRVGNVEYINALAKLIDPHSVEYED 163
> mmu:26462 Txnrd2, AA118373, ESTM573010, TGR, Tr3, Trxr2, Trxrd2;
thioredoxin reductase 2 (EC:1.8.1.9); K00384 thioredoxin
reductase (NADPH) [EC:1.8.1.9]
Length=527
Score = 117 bits (292), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 66/142 (46%), Positives = 85/142 (59%), Gaps = 13/142 (9%)
Query 8 DYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKLLH 67
+D +VIGGGSGGLA K+AA LG +V V D+V+PS RG WGLGGTCVNVGCIPKKL+H
Sbjct 42 SFDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKKLMH 101
Query 68 FAAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQLNFSYRV 127
AA +LG + G+ Q +W+T+ E VQ+++K LN+ +RV
Sbjct 102 QAA-----------LLGG--MIRDAHHYGWEVAQPVQHNWKTMAEAVQNHVKSLNWGHRV 148
Query 128 GLQNAGCTYTRALARLVGPHTV 149
LQ+ Y A V HTV
Sbjct 149 QLQDRKVKYFNIKASFVDEHTV 170
> xla:447610 txnrd1, MGC85342; thioredoxin reductase 1 (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=531
Score = 116 bits (290), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 71/144 (49%), Positives = 89/144 (61%), Gaps = 13/144 (9%)
Query 7 FDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKLL 66
+DYD IVIGGGSGGLA+ K+AA G +VLVLDFV PS G WGLGGTCVNVGCIPKKL+
Sbjct 46 YDYDLIVIGGGSGGLAASKEAAKYGKKVLVLDFVTPSPLGTKWGLGGTCVNVGCIPKKLM 105
Query 67 HFAAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQLNFSYR 126
H AA RQ + ++ G +A N +W+T+ + VQ+YI LNF+YR
Sbjct 106 HQAALLRQ-ALKDSQKYGWQ--IADNIQH----------NWETMTDSVQNYIGSLNFNYR 152
Query 127 VGLQNAGCTYTRALARLVGPHTVE 150
V L Y VGP+T++
Sbjct 153 VALMENNVKYENGYGEFVGPNTIK 176
> xla:379744 txnrd2, MGC69182; thioredoxin reductase 2 (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=504
Score = 115 bits (287), Expect = 6e-26, Method: Compositional matrix adjust.
Identities = 65/143 (45%), Positives = 82/143 (57%), Gaps = 15/143 (10%)
Query 8 DYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKLLH 67
DYD +VIGGGSGGLA KQAA G +V V D+V+PS RG WG+GGTCVNVGCIPKKL+H
Sbjct 19 DYDLLVIGGGSGGLACAKQAAQFGKKVAVFDYVEPSPRGTKWGIGGTCVNVGCIPKKLMH 78
Query 68 FAAQTRQFGVWEAPMLGC-NPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQLNFSYR 126
AA + +AP G PY + DW + VQ+Y+K LN+ +R
Sbjct 79 QAALIGST-MKDAPHYGWGTPYEIQH-------------DWGKMAGAVQNYVKSLNWGHR 124
Query 127 VGLQNAGCTYTRALARLVGPHTV 149
+ LQ+ Y A V H +
Sbjct 125 IQLQDKKVKYFNLKANFVDEHCI 147
> tpv:TP03_0110 thioredoxin reductase (EC:1.6.4.5); K00384 thioredoxin
reductase (NADPH) [EC:1.8.1.9]
Length=567
Score = 107 bits (267), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 65/150 (43%), Positives = 87/150 (58%), Gaps = 26/150 (17%)
Query 9 YDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKLLHF 68
YD +V+GGG G+A+ K+AA LG R ++ D+V PS RG SWG+GGTCVNVGCIPKKL+H+
Sbjct 91 YDLVVLGGGPAGMAAAKEAARLGKRTVLFDYVTPSPRGTSWGVGGTCVNVGCIPKKLMHY 150
Query 69 AAQTR-------QFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQL 121
A+ R Q+G+ +P + +W L + +Q+Y+K L
Sbjct 151 ASLLRSTQYDRFQYGITSSP-------------------DQEQVNWTKLTQTIQNYVKML 191
Query 122 NFSYRVGLQNAGCTYTRALARLVGPHTVEY 151
NFSYR GL AG Y A L +TVEY
Sbjct 192 NFSYRSGLTTAGVDYINAYGTLKHNNTVEY 221
> hsa:10587 TXNRD2, SELZ, TR, TR-BETA, TR3, TRXR2; thioredoxin
reductase 2 (EC:1.8.1.9); K00384 thioredoxin reductase (NADPH)
[EC:1.8.1.9]
Length=524
Score = 103 bits (256), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 68/142 (47%), Positives = 88/142 (61%), Gaps = 13/142 (9%)
Query 8 DYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKLLH 67
DYD +V+GGGSGGLA K+AA LG +V V+D+V+PS +G WGLGGTCVNVGCIPKKL+H
Sbjct 39 DYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMH 98
Query 68 FAAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQLNFSYRV 127
AA +LG + P G+ Q P DW+ + E VQ+++K LN+ +RV
Sbjct 99 QAA-----------LLGG--LIQDAPNYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHRV 145
Query 128 GLQNAGCTYTRALARLVGPHTV 149
LQ+ Y A V HTV
Sbjct 146 QLQDRKVKYFNIKASFVDEHTV 167
> mmu:232223 Txnrd3, AI196535, TR2, Tgr; thioredoxin reductase
3 (EC:1.8.1.9); K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=652
Score = 103 bits (256), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 68/143 (47%), Positives = 88/143 (61%), Gaps = 13/143 (9%)
Query 8 DYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKLLH 67
DYD I+IGGGSGGL+ K+AA LG +V+VLDFV PS +G +WGLGGTCVNVGCIPKKL+H
Sbjct 165 DYDLIIIGGGSGGLSCAKEAANLGKKVMVLDFVVPSPQGTTWGLGGTCVNVGCIPKKLMH 224
Query 68 FAAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQLNFSYRV 127
AA +LG A G+ NQ +W+ + E +QS+I LN+ YRV
Sbjct 225 QAA-----------LLGHALQDAKK--YGWEYNQQVKHNWEAMTEAIQSHIGSLNWGYRV 271
Query 128 GLQNAGCTYTRALARLVGPHTVE 150
L+ G TY + V H ++
Sbjct 272 TLREKGVTYVNSFGEFVDLHKIK 294
> cel:C06G3.7 trxr-1; ThioRedoXin Reductase family member (trxr-1);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=667
Score = 102 bits (253), Expect = 6e-22, Method: Compositional matrix adjust.
Identities = 66/141 (46%), Positives = 85/141 (60%), Gaps = 12/141 (8%)
Query 9 YDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKLLHF 68
YD IVIGGGSGGLA+ K+A+ LG +V LDFVKPS +G SWGLGGTCVNVGCIPKKL+H
Sbjct 173 YDLIVIGGGSGGLAAAKEASRLGKKVACLDFVKPSPQGTSWGLGGTCVNVGCIPKKLMH- 231
Query 69 AAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQLNFSYRVG 128
+A +LG + + A PE +++ W L + VQ +I LN+ YRV
Sbjct 232 ----------QASLLGHSIHDAKKYGWKLPEGKVE-HQWNHLRDSVQDHIASLNWGYRVQ 280
Query 129 LQNAGCTYTRALARLVGPHTV 149
L+ TY + GP +
Sbjct 281 LREKTVTYINSYGEFTGPFEI 301
> mmu:50493 Txnrd1, TR, TR1, TrxR1; thioredoxin reductase 1 (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=499
Score = 102 bits (253), Expect = 7e-22, Method: Compositional matrix adjust.
Identities = 68/150 (45%), Positives = 88/150 (58%), Gaps = 27/150 (18%)
Query 7 FDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKLL 66
+D+D I+IGGGSGGLA+ K+AA +VLVLDFV P+ G WGLGGTCVNVGCIPKKL+
Sbjct 11 YDFDLIIIGGGSGGLAAAKEAAKFDKKVLVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLM 70
Query 67 HFAA-------QTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIK 119
H AA +R +G W+ E+ +K DW+ + E VQS+I
Sbjct 71 HQAALLGQALKDSRNYG-WKV------------------EDTVKH-DWEKMTESVQSHIG 110
Query 120 QLNFSYRVGLQNAGCTYTRALARLVGPHTV 149
LN+ YRV L+ Y A R +GPH +
Sbjct 111 SLNWGYRVALREKKVVYENAYGRFIGPHRI 140
> hsa:7296 TXNRD1, GRIM-12, MGC9145, TR, TR1, TRXR1, TXNR; thioredoxin
reductase 1 (EC:1.8.1.9); K00384 thioredoxin reductase
(NADPH) [EC:1.8.1.9]
Length=649
Score = 101 bits (251), Expect = 9e-22, Method: Compositional matrix adjust.
Identities = 66/146 (45%), Positives = 89/146 (60%), Gaps = 13/146 (8%)
Query 5 EKFDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKK 64
+ +DYD I+IGGGSGGLA+ K+AA G +V+VLDFV P+ G WGLGGTCVNVGCIPKK
Sbjct 159 KSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKK 218
Query 65 LLHFAAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQLNFS 124
L+H AA +LG + N G+ + DW ++E VQ++I LN+
Sbjct 219 LMHQAA-----------LLGQALQDSRN--YGWKVEETVKHDWDRMIEAVQNHIGSLNWG 265
Query 125 YRVGLQNAGCTYTRALARLVGPHTVE 150
YRV L+ Y A + +GPH ++
Sbjct 266 YRVALREKKVVYENAYGQFIGPHRIK 291
> hsa:114112 TXNRD3, TGR, TR2, TRXR3; thioredoxin reductase 3
(EC:1.8.1.9); K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=607
Score = 101 bits (251), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 66/151 (43%), Positives = 89/151 (58%), Gaps = 27/151 (17%)
Query 7 FDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKLL 66
+DYD I+IGGGSGGL+ K+AA LG +V+VLDFV PS +G SWGLGGTCVNVGCIPKKL+
Sbjct 155 YDYDLIIIGGGSGGLSCAKEAAILGKKVMVLDFVVPSPQGTSWGLGGTCVNVGCIPKKLM 214
Query 67 HFAA-------QTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIK 119
H AA +R+FG WE NQ +W+T+ + +Q++I
Sbjct 215 HQAALLGQALCDSRKFG-WEY-------------------NQQVRHNWETMTKAIQNHIS 254
Query 120 QLNFSYRVGLQNAGCTYTRALARLVGPHTVE 150
LN+ YR+ L+ Y + V H ++
Sbjct 255 SLNWGYRLSLREKAVAYVNSYGEFVEHHKIK 285
> cel:ZK637.10 trxr-2; ThioRedoXin Reductase family member (trxr-2);
K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=503
Score = 100 bits (249), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 62/147 (42%), Positives = 80/147 (54%), Gaps = 13/147 (8%)
Query 3 STEKFDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIP 62
S+ KFD IVIG GSGGL+ K+AA LGA V ++D V+P+ G SWG+GGTC NVGCIP
Sbjct 17 SSNKFDL--IVIGAGSGGLSCSKRAADLGANVALIDAVEPTPHGHSWGIGGTCANVGCIP 74
Query 63 KKLLHFAAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQLN 122
KKL+H AA + + A G N G + ++K DW L + V +K N
Sbjct 75 KKLMHQAAIVGK-ELKHADKYGWN---------GIDQEKIKH-DWNVLSKNVNDRVKANN 123
Query 123 FSYRVGLQNAGCTYTRALARLVGPHTV 149
+ YRV L Y A A V +
Sbjct 124 WIYRVQLNQKKINYFNAYAEFVDKDKI 150
> tgo:TGME49_046920 glutathione reductase, putative (EC:1.8.1.7);
K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=483
Score = 74.7 bits (182), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 53/140 (37%), Positives = 69/140 (49%), Gaps = 26/140 (18%)
Query 9 YDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWG--LGGTCVNVGCIPKKLL 66
+D VIGGGSGGLA ++AA RV GL+ G LGGTCVNVGC+PKK++
Sbjct 13 FDLFVIGGGSGGLACARRAATYNVRV-----------GLADGNRLGGTCVNVGCVPKKVM 61
Query 67 HFAAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQLNFSYR 126
A + L F+ + Q C W+TL +YIK+LN Y
Sbjct 62 WCVASVHE------------TLHELKNFAFTVKEQPTFC-WRTLKTNRDNYIKRLNNIYL 108
Query 127 VGLQNAGCTYTRALARLVGP 146
L+N+G T+ A AR P
Sbjct 109 NNLKNSGVTFFPAYARFAKP 128
> ath:AT3G24170 ATGR1; ATGR1 (glutathione-disulfide reductase);
FAD binding / NADP or NADPH binding / glutathione-disulfide
reductase/ oxidoreductase (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=499
Score = 65.5 bits (158), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 45/154 (29%), Positives = 73/154 (47%), Gaps = 14/154 (9%)
Query 1 DGSTEKFDYDYIVIGGGSGGLASGKQAAGLGARVLVLDF-VKPSIRGLSWGLGGTCVNVG 59
+ + +D+D VIG GSGG+ + + +A GA+V + + P G+GGTCV G
Sbjct 18 EANATHYDFDLFVIGAGSGGVRAARFSANHGAKVGICELPFHPISSEEIGGVGGTCVIRG 77
Query 60 CIPKKLLHFAAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIK 119
C+PKK+L + A + + Y G+ N+ W+ L+++ I
Sbjct 78 CVPKKILVYGA------TYGGELEDAKNY-------GWEINEKVDFTWKKLLQKKTDEIL 124
Query 120 QLNFSYRVGLQNAGCTYTRALARLVGPHTVEYEE 153
+LN Y+ L NA R+VGP+ VE +
Sbjct 125 RLNNIYKRLLANAAVKLYEGEGRVVGPNEVEVRQ 158
> hsa:2936 GSR, MGC78522; glutathione reductase (EC:1.8.1.7);
K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=522
Score = 64.3 bits (155), Expect = 1e-10, Method: Composition-based stats.
Identities = 52/133 (39%), Positives = 71/133 (53%), Gaps = 23/133 (17%)
Query 9 YDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKLLHF 68
YDY+VIGGGSGGLAS ++AA LGAR V++ S LGGTCVNVGC+PKK++
Sbjct 65 YDYLVIGGGSGGLASARRAAELGARAAVVE---------SHKLGGTCVNVGCVPKKVMWN 115
Query 69 AAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQLNFSYRVG 128
A +F M Y GFP + K +W+ + E+ +Y+ +LN Y+
Sbjct 116 TAVHSEF------MHDHADY-------GFPSCEGK-FNWRVIKEKRDAYVSRLNAIYQNN 161
Query 129 LQNAGCTYTRALA 141
L + R A
Sbjct 162 LTKSHIEIIRGHA 174
> ath:AT3G54660 GR; GR (GLUTATHIONE REDUCTASE); ATP binding /
glutathione-disulfide reductase (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=565
Score = 63.9 bits (154), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 43/153 (28%), Positives = 70/153 (45%), Gaps = 18/153 (11%)
Query 3 STEKFDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRG-LSWGLGGTCVNVGCI 61
S +D+D IG GSGG+ + + A GA V + +I + G+GGTCV GC+
Sbjct 82 SDRHYDFDLFTIGAGSGGVRASRFATSFGASAAVCELPFSTISSDTAGGVGGTCVLRGCV 141
Query 62 PKKLLHFAAQTRQFGVWEAPMLGCNPYVALNPFSGFP-ENQLKPC-DWQTLVERVQSYIK 119
PKKLL +A++ GF + + +P DW TL+ + ++
Sbjct 142 PKKLLVYASKYSH---------------EFEDSHGFGWKYETEPSHDWTTLIANKNAELQ 186
Query 120 QLNFSYRVGLQNAGCTYTRALARLVGPHTVEYE 152
+L Y+ L A +++ PHTV+ +
Sbjct 187 RLTGIYKNILSKANVKLIEGRGKVIDPHTVDVD 219
> xla:734372 gsr, MGC84926; glutathione reductase (EC:1.8.1.7);
K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=476
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 52/135 (38%), Positives = 72/135 (53%), Gaps = 23/135 (17%)
Query 9 YDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKLLHF 68
YDY+V+GGGSGGLAS ++AA LGAR V++ K LGGTCVNVGC+PKK++
Sbjct 19 YDYLVVGGGSGGLASARRAAELGARTAVVESSK---------LGGTCVNVGCVPKKIM-- 67
Query 69 AAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQLNFSYRVG 128
W A M + Y+ + GF +K W+ + E+ +Y+ +LN Y+
Sbjct 68 ---------WNAAM--HSEYIHDHADYGFEIPDVK-FTWKVIKEKRDAYVSRLNDIYQNN 115
Query 129 LQNAGCTYTRALARL 143
LQ A R A
Sbjct 116 LQKAQIEIIRGNANF 130
> sce:YPL091W GLR1, LPG17; Cytosolic and mitochondrial glutathione
oxidoreductase, converts oxidized glutathione to reduced
glutathione; mitochondrial but not cytosolic form has a role
in resistance to hyperoxia (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=483
Score = 57.8 bits (138), Expect = 1e-08, Method: Composition-based stats.
Identities = 46/158 (29%), Positives = 77/158 (48%), Gaps = 31/158 (19%)
Query 3 STEKFDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIP 62
ST YDY+VIGGGSGG+AS ++AA GA+ L+++ + LGGTCVNVGC+P
Sbjct 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVE---------AKALGGTCVNVGCVP 68
Query 63 KKLLHFA-------AQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQ 115
KK++ +A + ++G+++ L + + +W ++
Sbjct 69 KKVMWYASDLATRVSHANEYGLYQNLPL---------------DKEHLTFNWPEFKQKRD 113
Query 116 SYIKQLNFSYRVGLQNAGCTYTRALARLVGPHTVEYEE 153
+Y+ +LN Y+ L+ AR VE ++
Sbjct 114 AYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQK 151
> eco:b3500 gor, ECK3485, gorA, JW3467; glutathione oxidoreductase
(EC:1.8.1.7); K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=450
Score = 57.4 bits (137), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 34/100 (34%), Positives = 49/100 (49%), Gaps = 13/100 (13%)
Query 51 LGGTCVNVGCIPKKLLHFAAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTL 110
LGGTCVNVGC+PKK++ AAQ R+ P G + +N F +W+TL
Sbjct 38 LGGTCVNVGCVPKKVMWHAAQIREAIHMYGPDYGFD--TTINKF-----------NWETL 84
Query 111 VERVQSYIKQLNFSYRVGLQNAGCTYTRALARLVGPHTVE 150
+ +YI +++ SY L + AR V T+E
Sbjct 85 IASRTAYIDRIHTSYENVLGKNNVDVIKGFARFVDAKTLE 124
> mmu:14782 Gsr, AI325518, D8Ertd238e, Gr-1, Gr1; glutathione
reductase (EC:1.8.1.7); K00383 glutathione reductase (NADPH)
[EC:1.8.1.7]
Length=500
Score = 57.4 bits (137), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 47/124 (37%), Positives = 66/124 (53%), Gaps = 23/124 (18%)
Query 9 YDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKLLHF 68
+DY+VIGGGSGGLAS ++AA LGAR V++ S LGGTCVNVGC+PKK++
Sbjct 43 FDYLVIGGGSGGLASARRAAELGARAAVVE---------SHKLGGTCVNVGCVPKKVMWN 93
Query 69 AAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQLNFSYRVG 128
A +F M Y GF + K W + ++ +Y+ +LN Y+
Sbjct 94 TAVHSEF------MHDHVDY-------GFQSCEGK-FSWHVIKQKRDAYVSRLNTIYQNN 139
Query 129 LQNA 132
L +
Sbjct 140 LTKS 143
> cel:C46F11.2 hypothetical protein
Length=473
Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats.
Identities = 51/143 (35%), Positives = 75/143 (52%), Gaps = 23/143 (16%)
Query 8 DYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKLLH 67
++DY+VIGGGSGG+AS ++A G V +++ S LGGTCVNVGC+PKK+++
Sbjct 20 EFDYLVIGGGSGGIASARRAREFGVSVGLIE---------SGRLGGTCVNVGCVPKKVMY 70
Query 68 FAAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQLNFSYRV 127
+ +F + + G + V LN F DW+ + + YIK+LN Y
Sbjct 71 NCSLHAEF-IRDHADYGFD--VTLNKF-----------DWKVIKKSRDEYIKRLNGLYES 116
Query 128 GLQNAGCTYTRALARLVGPHTVE 150
GL+ + Y R A TVE
Sbjct 117 GLKGSSVEYIRGRATFAEDGTVE 139
> cel:LLC1.3 hypothetical protein; K00382 dihydrolipoamide dehydrogenase
[EC:1.8.1.4]
Length=495
Score = 55.1 bits (131), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 43/146 (29%), Positives = 69/146 (47%), Gaps = 22/146 (15%)
Query 8 DYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKLLH 67
D D +VIGGG GG + +AA LG + + ++ + LGGTC+NVGCIP K L
Sbjct 29 DADLVVIGGGPGGYVAAIKAAQLGMKTVCVE--------KNATLGGTCLNVGCIPSKALL 80
Query 68 FAAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQLNFSYRV 127
+ + G + +LN P+ + V+++ IKQL + +V
Sbjct 81 NNSHYLHMAQHDFAARGIDCTASLN----LPKMMEAKSNS---VKQLTGGIKQLFKANKV 133
Query 128 GLQNAGCTYTRALARLVGPHTVEYEE 153
G + A +VGP+TV+ ++
Sbjct 134 G-------HVEGFATIVGPNTVQAKK 152
> bbo:BBOV_IV007190 23.m05858; dihydrolipoamide dehydrogenase
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=481
Score = 51.6 bits (122), Expect = 1e-06, Method: Composition-based stats.
Identities = 29/64 (45%), Positives = 36/64 (56%), Gaps = 8/64 (12%)
Query 3 STEKFDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIP 62
S+ YD VIGGG GG + +AA G +V +D R + LGGTC+NVGCIP
Sbjct 18 SSATHKYDLAVIGGGPGGYTTAIKAAQYGLKVACID------RRTT--LGGTCLNVGCIP 69
Query 63 KKLL 66
K L
Sbjct 70 SKCL 73
> dre:100332932 glutathione reductase-like
Length=461
Score = 51.2 bits (121), Expect = 1e-06, Method: Composition-based stats.
Identities = 51/143 (35%), Positives = 67/143 (46%), Gaps = 23/143 (16%)
Query 7 FDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKLL 66
+DYD VIGGGSGG+ SG+ AA +G +V + + + GGTCV GC+PKKL
Sbjct 4 YDYDLFVIGGGSGGVRSGRVAASMGKKVGIAE---------EYRYGGTCVIRGCVPKKLF 54
Query 67 HFAAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQLNFSYR 126
+A+Q + A G V F DW L+ I +L YR
Sbjct 55 VYASQFHEHFEDSA---GFGWTVGETSF-----------DWAKLIAAKDREIDRLEGLYR 100
Query 127 VGLQNAGCTYTRALARLVGPHTV 149
GL+NA + A LV HTV
Sbjct 101 KGLENAKAKVFDSRAELVDAHTV 123
> dre:553575 MGC110010; zgc:110010 (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=425
Score = 49.3 bits (116), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 48/143 (33%), Positives = 68/143 (47%), Gaps = 25/143 (17%)
Query 2 GSTEKFDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCI 61
GS +F D++V+GGGSGGLA ++AA LGA V++ S LGGTCVNVGC+
Sbjct 4 GSVSRF--DFLVVGGGSGGLAGARRAAELGATTAVIE---------SHRLGGTCVNVGCV 52
Query 62 PKKLLHFAAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQL 121
PKK++ W Y+ + GF E WQ + + +Y+ +L
Sbjct 53 PKKVM-----------WNTSTHA--EYLHDHEDYGF-EGAKAHFSWQIIKHKRDAYVSRL 98
Query 122 NFSYRVGLQNAGCTYTRALARLV 144
N YR L+ + AR
Sbjct 99 NQIYRSNLEKGKIEFIHGYARFT 121
> tpv:TP03_0227 dihydrolipoamide dehydrogenase (EC:1.8.1.4); K00382
dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=499
Score = 47.4 bits (111), Expect = 2e-05, Method: Composition-based stats.
Identities = 27/64 (42%), Positives = 36/64 (56%), Gaps = 8/64 (12%)
Query 3 STEKFDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIP 62
ST YD +V+G G GG +AA G +V V++ +P+ LGGTC+N GCIP
Sbjct 18 STSSSKYDLLVLGAGPGGYTMAIKAAQHGLKVGVVE-KRPT-------LGGTCLNCGCIP 69
Query 63 KKLL 66
K L
Sbjct 70 SKSL 73
> sce:YFL018C LPD1, HPD1; Dihydrolipoamide dehydrogenase, the
lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase
and 2-oxoglutarate dehydrogenase multi-enzyme complexes
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=499
Score = 45.8 bits (107), Expect = 5e-05, Method: Composition-based stats.
Identities = 25/58 (43%), Positives = 33/58 (56%), Gaps = 8/58 (13%)
Query 9 YDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKLL 66
+D ++IGGG G + +AA LG ++ RG LGGTC+NVGCIP K L
Sbjct 27 HDVVIIGGGPAGYVAAIKAAQLGFNTACVE-----KRG---KLGGTCLNVGCIPSKAL 76
> pfa:PF08_0066 lipoamide dehydrogenase, putative (EC:1.8.1.4);
K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=666
Score = 45.1 bits (105), Expect = 9e-05, Method: Composition-based stats.
Identities = 25/62 (40%), Positives = 33/62 (53%), Gaps = 7/62 (11%)
Query 8 DYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKLLH 67
+YD +IG G GG A+ A +V++ G +GGTCVNVGCIP K L
Sbjct 125 EYDLAIIGCGVGGHAAAINAMERNLKVIIF-------AGDENCIGGTCVNVGCIPSKALL 177
Query 68 FA 69
+A
Sbjct 178 YA 179
> hsa:1738 DLD, DLDH, E3, GCSL, LAD, PHE3; dihydrolipoamide dehydrogenase
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase
[EC:1.8.1.4]
Length=509
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 25/64 (39%), Positives = 35/64 (54%), Gaps = 8/64 (12%)
Query 3 STEKFDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIP 62
+ + D D VIG G GG + +AA LG + + ++ + LGGTC+NVGCIP
Sbjct 36 ADQPIDADVTVIGSGPGGYVAAIKAAQLGFKTVCIE--------KNETLGGTCLNVGCIP 87
Query 63 KKLL 66
K L
Sbjct 88 SKAL 91
> dre:399479 dldh, wu:fb24b05; dihydrolipoamide dehydrogenase
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=507
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 24/60 (40%), Positives = 33/60 (55%), Gaps = 8/60 (13%)
Query 7 FDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKKLL 66
D D V+G G GG + +AA LG + + ++ + LGGTC+NVGCIP K L
Sbjct 39 IDADVTVVGSGPGGYVAAIKAAQLGFKTVCVE--------KNATLGGTCLNVGCIPSKAL 90
> pfa:PF14_0192 glutathione reductase (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=500
Score = 42.4 bits (98), Expect = 5e-04, Method: Composition-based stats.
Identities = 29/79 (36%), Positives = 38/79 (48%), Gaps = 15/79 (18%)
Query 51 LGGTCVNVGCIPKKLLHFAAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTL 110
LGGTCVNVGC+PKK++ AA + + G + + N P L
Sbjct 36 LGGTCVNVGCVPKKIMFNAASVHDI-LENSRHYGFDTKFSFN----LP----------LL 80
Query 111 VERVQSYIKQLNFSYRVGL 129
VER YI++LN YR L
Sbjct 81 VERRDKYIQRLNNIYRQNL 99
> xla:380588 dld, MGC68940; dihydrolipoamide dehydrogenase (EC:1.8.1.4);
K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=509
Score = 42.0 bits (97), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 8/64 (12%)
Query 3 STEKFDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIP 62
S + + D V+G G GG + +AA LG + + ++ + LGGTC+NVGCIP
Sbjct 36 SEKAIEADVTVVGSGPGGYVAAIKAAQLGFQTVCVE--------KNDTLGGTCLNVGCIP 87
Query 63 KKLL 66
K L
Sbjct 88 SKAL 91
> mmu:13382 Dld, AI315664, AI746344; dihydrolipoamide dehydrogenase
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=509
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 23/64 (35%), Positives = 35/64 (54%), Gaps = 8/64 (12%)
Query 3 STEKFDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIP 62
+ + + D VIG G GG + ++A LG + + ++ + LGGTC+NVGCIP
Sbjct 36 ADQPIEADVTVIGSGPGGYVAAIKSAQLGFKTVCIE--------KNETLGGTCLNVGCIP 87
Query 63 KKLL 66
K L
Sbjct 88 SKAL 91
> eco:b0116 lpd, dhl, ECK0115, JW0112, lpdA; lipoamide dehydrogenase,
E3 component is part of three enzyme complexes (EC:1.8.1.4);
K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=474
Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats.
Identities = 22/59 (37%), Positives = 32/59 (54%), Gaps = 9/59 (15%)
Query 12 IVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKK-LLHFA 69
+V+G G G ++ + A LG ++++ LGG C+NVGCIP K LLH A
Sbjct 10 VVLGAGPAGYSAAFRCADLGLETVIVERYNT--------LGGVCLNVGCIPSKALLHVA 60
> eco:b3962 sthA, ECK3954, JW5551, sth, udhA; pyridine nucleotide
transhydrogenase, soluble (EC:1.6.1.1); K00322 NAD(P) transhydrogenase
[EC:1.6.1.1]
Length=466
Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 37/145 (25%), Positives = 58/145 (40%), Gaps = 22/145 (15%)
Query 5 EKFDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKK 64
+DYD IVIG G GG + GARV V++ + +GG C + G IP K
Sbjct 3 HSYDYDAIVIGSGPGGEGAAMGLVKQGARVAVIERYQ--------NVGGGCTHWGTIPSK 54
Query 65 LLHFAAQTRQFGVWEAPMLGCNPYVALNPFSGFPENQLKPCDWQTLVERVQSYIKQLNFS 124
L A +R + P+ + + + F+ + + QT R++ + N
Sbjct 55 ALRHAV-SRIIEFNQNPLYSDHSRLLRSSFADILNHADNVINQQT---RMRQGFYERNH- 109
Query 125 YRVGLQNAGCTYTRALARLVGPHTV 149
C + AR V HT+
Sbjct 110 ---------CEILQGNARFVDEHTL 125
> eco:b0304 ykgC, ECK0303, JW5040; predicted pyridine nucleotide-disulfide
oxidoreductase
Length=441
Score = 38.1 bits (87), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 8/68 (11%)
Query 9 YDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIP-KKLLH 67
Y ++IG G G A G RV + I + GGTC+N+GCIP K L+H
Sbjct 4 YQAVIIGFGKAGKTLAVTLAKAGWRVAL-------IEQSNAMYGGTCINIGCIPTKTLVH 56
Query 68 FAAQTRQF 75
A Q F
Sbjct 57 DAQQHTDF 64
> ath:AT3G17240 mtLPD2; mtLPD2 (LIPOAMIDE DEHYDROGENASE 2); ATP
binding / dihydrolipoyl dehydrogenase; K00382 dihydrolipoamide
dehydrogenase [EC:1.8.1.4]
Length=507
Score = 38.1 bits (87), Expect = 0.011, Method: Composition-based stats.
Identities = 29/61 (47%), Positives = 37/61 (60%), Gaps = 9/61 (14%)
Query 8 DYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCIPKK-LL 66
D D ++IGGG GG + +AA LG + ++ RG LGGTC+NVGCIP K LL
Sbjct 43 DNDVVIIGGGPGGYVAAIKAAQLGLKTTCIE-----KRG---ALGGTCLNVGCIPSKALL 94
Query 67 H 67
H
Sbjct 95 H 95
> ath:AT1G48030 mtLPD1; mtLPD1 (mitochondrial lipoamide dehydrogenase
1); ATP binding / dihydrolipoyl dehydrogenase; K00382
dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=507
Score = 35.4 bits (80), Expect = 0.067, Method: Composition-based stats.
Identities = 30/67 (44%), Positives = 39/67 (58%), Gaps = 12/67 (17%)
Query 2 GSTEKFDYDYIVIGGGSGGLASGKQAAGLGARVLVLDFVKPSIRGLSWGLGGTCVNVGCI 61
GS E D ++IGGG GG + +A+ LG + ++ RG LGGTC+NVGCI
Sbjct 40 GSDEN---DVVIIGGGPGGYVAAIKASQLGLKTTCIE-----KRG---ALGGTCLNVGCI 88
Query 62 PKK-LLH 67
P K LLH
Sbjct 89 PSKALLH 95
> ath:AT1G06820 CRTISO; CRTISO (CAROTENOID ISOMERASE); carotenoid
isomerase; K09835 carotenoid isomerase [EC:5.-.-.-]
Length=595
Score = 33.9 bits (76), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 18/30 (60%), Positives = 20/30 (66%), Gaps = 0/30 (0%)
Query 9 YDYIVIGGGSGGLASGKQAAGLGARVLVLD 38
YD IVIG G GGL + Q A ARVLVL+
Sbjct 78 YDAIVIGSGIGGLVAATQLAVKEARVLVLE 107
> pfa:PFL1550w lipoamide dehydrogenase (EC:1.8.1.4); K00382 dihydrolipoamide
dehydrogenase [EC:1.8.1.4]
Length=512
Score = 33.5 bits (75), Expect = 0.27, Method: Composition-based stats.
Identities = 17/29 (58%), Positives = 20/29 (68%), Gaps = 6/29 (20%)
Query 51 LGGTCVNVGCIP-KKLLH-----FAAQTR 73
LGGTC+N GCIP K LLH + A+TR
Sbjct 59 LGGTCLNRGCIPSKSLLHISHNYYEAKTR 87
> mmu:67442 Retsat, 0610039N19Rik, C80029, MGC143538, MMT-7, Ppsig;
retinol saturase (all trans retinol 13,14 reductase) (EC:1.3.99.23);
K09516 all-trans-retinol 13,14-reductase [EC:1.3.99.23]
Length=609
Score = 33.1 bits (74), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 17/29 (58%), Positives = 19/29 (65%), Gaps = 0/29 (0%)
Query 10 DYIVIGGGSGGLASGKQAAGLGARVLVLD 38
D +VIG G GGLAS A G RVLVL+
Sbjct 68 DAVVIGSGIGGLASAAVLAKAGKRVLVLE 96
> dre:677660 retsatl, wu:fi35b01, zgc:123334; retinol saturase
(all-trans-retinol 13,14-reductase) like; K09516 all-trans-retinol
13,14-reductase [EC:1.3.99.23]
Length=604
Score = 32.3 bits (72), Expect = 0.68, Method: Compositional matrix adjust.
Identities = 16/31 (51%), Positives = 20/31 (64%), Gaps = 0/31 (0%)
Query 8 DYDYIVIGGGSGGLASGKQAAGLGARVLVLD 38
+ D IVIG G GGL + A LG +VLVL+
Sbjct 63 NLDVIVIGSGIGGLTAAAVLARLGKKVLVLE 93
> mmu:666752 Gm8273, EG666752; predicted gene 8273
Length=150
Score = 31.6 bits (70), Expect = 0.98, Method: Compositional matrix adjust.
Identities = 13/36 (36%), Positives = 19/36 (52%), Gaps = 3/36 (8%)
Query 54 TCVNVGCIPKKLLHFAAQTRQFGVWEAP---MLGCN 86
TC+ GC+P+ LL +R G+W P + GC
Sbjct 42 TCLRRGCVPRALLPSPPASRTSGLWSRPPPAVPGCR 77
> tgo:TGME49_006470 dihydrolipoyl dehydrogenase, putative (EC:1.8.1.4);
K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=519
Score = 31.6 bits (70), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 12/14 (85%), Positives = 13/14 (92%), Gaps = 0/14 (0%)
Query 51 LGGTCVNVGCIPKK 64
LGGTC+NVGCIP K
Sbjct 84 LGGTCLNVGCIPSK 97
Lambda K H
0.321 0.140 0.448
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 3256415000
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
Posted date: Sep 17, 2011 2:57 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40