bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
164,496 sequences; 82,071,388 total letters
Query= Eten_1823_orf1
Length=173
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_034190 glycine hydroxymethyltransferase, putative (... 216 2e-56
xla:447193 shmt2, MGC79128; serine hydroxymethyltransferase 2 ... 204 2e-52
hsa:6472 SHMT2, GLYA, SHMT; serine hydroxymethyltransferase 2 ... 202 5e-52
xla:380048 shmt1, MGC53442; serine hydroxymethyltransferase 1 ... 201 2e-51
mmu:108037 Shmt2, 2700043D08Rik, AA408223, AA986903; serine hy... 200 2e-51
mmu:20425 Shmt1, AI324848, AI385541, C81125, Shmt, mshmt, mshm... 200 2e-51
bbo:BBOV_IV005840 23.m06426; serine hydroxymethyltransferase (... 200 2e-51
hsa:6470 SHMT1, CSHMT, MGC15229, MGC24556, SHMT; serine hydrox... 199 3e-51
dre:394021 shmt1, MGC66171, zgc:66171, zgc:77524; serine hydro... 196 3e-50
ath:AT4G13930 SHM4; SHM4 (serine hydroxymethyltransferase 4); ... 196 3e-50
ath:AT4G13890 EDA36; EDA36 (EMBRYO SAC DEVELOPMENT ARREST 37);... 196 4e-50
dre:100144628 shmt2; serine hydroxymethyltransferase 2 (mitoch... 195 5e-50
ath:AT4G32520 SHM3; SHM3 (SERINE HYDROXYMETHYLTRANSFERASE 3); ... 194 8e-50
cel:C05D11.11 mel-32; Maternal Effect Lethal family member (me... 191 8e-49
tpv:TP01_0390 serine hydroxymethyltransferase; K00600 glycine ... 189 3e-48
ath:AT4G37930 SHM1; SHM1 (SERINE TRANSHYDROXYMETHYLTRANSFERASE... 186 4e-47
ath:AT1G36370 SHM7; SHM7 (serine hydroxymethyltransferase 7); ... 178 1e-44
ath:AT1G22020 SHM6; SHM6 (serine hydroxymethyltransferase 6); ... 176 3e-44
ath:AT5G26780 SHM2; SHM2 (SERINE HYDROXYMETHYLTRANSFERASE 2); ... 175 7e-44
sce:YLR058C SHM2, SHMT2; Cytosolic serine hydroxymethyltransfe... 172 5e-43
pfa:PFL1720w serine hydroxymethyltransferase (EC:2.1.2.1); K00... 163 2e-40
sce:YBR263W SHM1, SHMT1, TMP3; Mitochondrial serine hydroxymet... 161 1e-39
cpv:cgd8_2610 cytosolic serine hydroxymethyl transferase ; K00... 145 8e-35
eco:b2551 glyA, ECK2548, JW2535; serine hydroxymethyltransfera... 139 6e-33
cpv:cgd8_2580 mitochondrial serine hydroxymethyl transferase 101 1e-21
hsa:10129 FRY, 13CDNA73, 214K23.2, C13orf14, CG003, bA207N4.2,... 32.3 0.86
mmu:98303 D630023F18Rik, AI314969; RIKEN cDNA D630023F18 gene 32.0 1.1
xla:100126659 fry; furry homolog 31.6 1.4
mmu:320365 Fry, 13CDNA73, 9330186A19Rik, AF346502, AI462658, C... 31.2 2.0
dre:100034467 si:ch211-132b12.1 29.6 5.4
> tgo:TGME49_034190 glycine hydroxymethyltransferase, putative
(EC:2.1.2.1); K00600 glycine hydroxymethyltransferase [EC:2.1.2.1]
Length=595
Score = 216 bits (551), Expect = 2e-56, Method: Compositional matrix adjust.
Identities = 105/149 (70%), Positives = 117/149 (78%), Gaps = 0/149 (0%)
Query 2 MQPLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARY 61
+Q L DPELY LL +EK RQ+ +ELIASENF S AV ECLGSCLTNKYSEG GARY
Sbjct 151 LQALATQDPELYELLREEKRRQISGLELIASENFTSQAVMECLGSCLTNKYSEGYPGARY 210
Query 62 YGGMEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLG 121
YGG E +D+IE LC +RA AFGLD EEW VNVQP+SGSPAN AV + LLQPHDR MGL
Sbjct 211 YGGNEVIDRIECLCQRRALAAFGLDIEEWAVNVQPYSGSPANMAVFVGLLQPHDRIMGLD 270
Query 122 LNDGGHLTHGAYTPSRRISATSLFYESLP 150
L GGHLTHG YT +RISATS+F+ESLP
Sbjct 271 LPSGGHLTHGFYTAKKRISATSIFFESLP 299
> xla:447193 shmt2, MGC79128; serine hydroxymethyltransferase
2 (mitochondrial) (EC:2.1.2.1); K00600 glycine hydroxymethyltransferase
[EC:2.1.2.1]
Length=496
Score = 204 bits (518), Expect = 2e-52, Method: Compositional matrix adjust.
Identities = 97/148 (65%), Positives = 114/148 (77%), Gaps = 0/148 (0%)
Query 3 QPLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYY 62
+ + E DPE++ L+ KEK+RQ +ELIASENF S A E LGSCL NKYSEG G RYY
Sbjct 39 ESMAEGDPEMWDLVQKEKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYY 98
Query 63 GGMEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGL 122
GG E VDQIE LC QRA +AF LDPE+W VNVQP+SGSPANFA A+LQPHDR MGL L
Sbjct 99 GGAEVVDQIELLCQQRALDAFDLDPEKWGVNVQPYSGSPANFAAYTAVLQPHDRIMGLDL 158
Query 123 NDGGHLTHGAYTPSRRISATSLFYESLP 150
DGGHLTHG + +RISATS+++ES+P
Sbjct 159 PDGGHLTHGYMSDVKRISATSIYFESMP 186
> hsa:6472 SHMT2, GLYA, SHMT; serine hydroxymethyltransferase
2 (mitochondrial) (EC:2.1.2.1); K00600 glycine hydroxymethyltransferase
[EC:2.1.2.1]
Length=494
Score = 202 bits (514), Expect = 5e-52, Method: Compositional matrix adjust.
Identities = 97/148 (65%), Positives = 114/148 (77%), Gaps = 0/148 (0%)
Query 3 QPLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYY 62
+ L ++DPE++ LL +EK+RQ +ELIASENF S A E LGSCL NKYSEG G RYY
Sbjct 47 ESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYY 106
Query 63 GGMEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGL 122
GG E VD+IE LC +RA EAF LDP +W VNVQP+SGSPAN AV ALLQPHDR MGL L
Sbjct 107 GGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDL 166
Query 123 NDGGHLTHGAYTPSRRISATSLFYESLP 150
DGGHLTHG + +RISATS+F+ES+P
Sbjct 167 PDGGHLTHGYMSDVKRISATSIFFESMP 194
> xla:380048 shmt1, MGC53442; serine hydroxymethyltransferase
1 (soluble) (EC:2.1.2.1); K00600 glycine hydroxymethyltransferase
[EC:2.1.2.1]
Length=485
Score = 201 bits (510), Expect = 2e-51, Method: Compositional matrix adjust.
Identities = 93/150 (62%), Positives = 116/150 (77%), Gaps = 0/150 (0%)
Query 1 CMQPLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGAR 60
++PL DPE+Y ++ KEK RQ +ELIASENF S AV + LGSCL NKYSEG G R
Sbjct 23 VLEPLDTNDPEVYEIIRKEKHRQRYGLELIASENFASCAVLQALGSCLNNKYSEGYPGQR 82
Query 61 YYGGMEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGL 120
YYGG EFVD++E LC +RA E +GL+P++W VNVQP+SGSPANFA+ AL++PH R MGL
Sbjct 83 YYGGTEFVDEMERLCQKRALEVYGLEPQKWGVNVQPYSGSPANFAIYTALVEPHGRIMGL 142
Query 121 GLNDGGHLTHGAYTPSRRISATSLFYESLP 150
L DGGHLTHG T ++ISATS+F+ES+P
Sbjct 143 DLPDGGHLTHGFMTDKKKISATSIFFESMP 172
> mmu:108037 Shmt2, 2700043D08Rik, AA408223, AA986903; serine
hydroxymethyltransferase 2 (mitochondrial) (EC:2.1.2.1); K00600
glycine hydroxymethyltransferase [EC:2.1.2.1]
Length=504
Score = 200 bits (509), Expect = 2e-51, Method: Compositional matrix adjust.
Identities = 96/148 (64%), Positives = 113/148 (76%), Gaps = 0/148 (0%)
Query 3 QPLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYY 62
+ L ++DPE++ LL +EK+RQ +ELIASENF S A E LGSCL NKYSEG G RYY
Sbjct 47 ESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYY 106
Query 63 GGMEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGL 122
GG E VD+IE LC +RA EAF LDP +W VNVQP+SGSPAN A ALLQPHDR MGL L
Sbjct 107 GGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDL 166
Query 123 NDGGHLTHGAYTPSRRISATSLFYESLP 150
DGGHLTHG + +RISATS+F+ES+P
Sbjct 167 PDGGHLTHGYMSDVKRISATSIFFESMP 194
> mmu:20425 Shmt1, AI324848, AI385541, C81125, Shmt, mshmt, mshmt1,
mshmt2; serine hydroxymethyltransferase 1 (soluble) (EC:2.1.2.1);
K00600 glycine hydroxymethyltransferase [EC:2.1.2.1]
Length=478
Score = 200 bits (508), Expect = 2e-51, Method: Compositional matrix adjust.
Identities = 94/148 (63%), Positives = 116/148 (78%), Gaps = 0/148 (0%)
Query 3 QPLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYY 62
QPLK++D E+Y+++ KE RQ +ELIASENF S AV E LGSCL NKYSEG G RYY
Sbjct 18 QPLKDSDAEVYSIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYY 77
Query 63 GGMEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGL 122
GG EF+D++E LC +RA +A+ LDP+ W VNVQP+SGSPANFAV AL++PH R MGL L
Sbjct 78 GGTEFIDELEMLCQKRALQAYHLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDL 137
Query 123 NDGGHLTHGAYTPSRRISATSLFYESLP 150
DGGHLTHG T ++ISATS+F+ES+P
Sbjct 138 PDGGHLTHGFMTDKKKISATSIFFESMP 165
> bbo:BBOV_IV005840 23.m06426; serine hydroxymethyltransferase
(EC:2.1.2.1); K00600 glycine hydroxymethyltransferase [EC:2.1.2.1]
Length=453
Score = 200 bits (508), Expect = 2e-51, Method: Compositional matrix adjust.
Identities = 95/146 (65%), Positives = 112/146 (76%), Gaps = 0/146 (0%)
Query 4 PLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYYG 63
PL++ADPE+Y +L +E+ERQ D I+LIASEN VSTAV E LGS TNKYSEG G RYYG
Sbjct 15 PLQQADPEIYEILQEERERQRDSIDLIASENMVSTAVLEALGSVFTNKYSEGYPGRRYYG 74
Query 64 GMEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGLN 123
G + VD++E LCI RA AF L+P+EW VNVQP SGSPAN V M LLQPHD+ MGL L
Sbjct 75 GCDVVDKLERLCISRALRAFNLNPDEWGVNVQPLSGSPANLEVYMGLLQPHDKIMGLRLA 134
Query 124 DGGHLTHGAYTPSRRISATSLFYESL 149
GGHLTHG Y ++ISAT++FY SL
Sbjct 135 SGGHLTHGFYVGQKKISATAVFYTSL 160
> hsa:6470 SHMT1, CSHMT, MGC15229, MGC24556, SHMT; serine hydroxymethyltransferase
1 (soluble) (EC:2.1.2.1); K00600 glycine
hydroxymethyltransferase [EC:2.1.2.1]
Length=483
Score = 199 bits (507), Expect = 3e-51, Method: Compositional matrix adjust.
Identities = 94/148 (63%), Positives = 115/148 (77%), Gaps = 0/148 (0%)
Query 3 QPLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYY 62
QPLK++D E+Y ++ KE RQ +ELIASENF S AV E LGSCL NKYSEG G RYY
Sbjct 24 QPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYY 83
Query 63 GGMEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGL 122
GG EF+D++E LC +RA +A+ LDP+ W VNVQP+SGSPANFAV AL++PH R MGL L
Sbjct 84 GGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDL 143
Query 123 NDGGHLTHGAYTPSRRISATSLFYESLP 150
DGGHLTHG T ++ISATS+F+ES+P
Sbjct 144 PDGGHLTHGFMTDKKKISATSIFFESMP 171
> dre:394021 shmt1, MGC66171, zgc:66171, zgc:77524; serine hydroxymethyltransferase
1 (soluble) (EC:2.1.2.1); K00600 glycine
hydroxymethyltransferase [EC:2.1.2.1]
Length=481
Score = 196 bits (499), Expect = 3e-50, Method: Compositional matrix adjust.
Identities = 91/149 (61%), Positives = 114/149 (76%), Gaps = 0/149 (0%)
Query 2 MQPLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARY 61
++PL DPE++ ++ KEK+RQ +ELIASENF S AV E LGSC+ NKYSEG G RY
Sbjct 20 LEPLSTNDPEVFDIIKKEKKRQTYGLELIASENFTSRAVLEALGSCMNNKYSEGYPGQRY 79
Query 62 YGGMEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLG 121
YGG E VD++E LC RA + +GLDPE+W VNVQP+SGS ANFAV A+++PH R MGL
Sbjct 80 YGGTEHVDELERLCQDRALKVYGLDPEKWGVNVQPYSGSRANFAVYTAIVEPHGRIMGLD 139
Query 122 LNDGGHLTHGAYTPSRRISATSLFYESLP 150
L DGGHLTHG T ++ISATS+F+ES+P
Sbjct 140 LPDGGHLTHGFMTDKKKISATSIFFESMP 168
> ath:AT4G13930 SHM4; SHM4 (serine hydroxymethyltransferase 4);
catalytic/ glycine hydroxymethyltransferase/ pyridoxal phosphate
binding (EC:2.1.2.1); K00600 glycine hydroxymethyltransferase
[EC:2.1.2.1]
Length=471
Score = 196 bits (498), Expect = 3e-50, Method: Compositional matrix adjust.
Identities = 100/154 (64%), Positives = 111/154 (72%), Gaps = 1/154 (0%)
Query 5 LKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYYGG 64
L DPE++ L+ KEK RQ IELIASENF S AV E LGS LTNKYSEG G RYYGG
Sbjct 12 LVSVDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGIPGNRYYGG 71
Query 65 MEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGLND 124
EF+D+IE LC RA EAF DP W VNVQP+SGSPANFA ALLQPHDR MGL L
Sbjct 72 NEFIDEIENLCRSRALEAFHCDPAAWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPS 131
Query 125 GGHLTHGAYTP-SRRISATSLFYESLPCHQGFVT 157
GGHLTHG YT ++ISATS+++ESLP F T
Sbjct 132 GGHLTHGYYTSGGKKISATSIYFESLPYKVNFTT 165
> ath:AT4G13890 EDA36; EDA36 (EMBRYO SAC DEVELOPMENT ARREST 37);
catalytic/ glycine hydroxymethyltransferase/ pyridoxal phosphate
binding (EC:2.1.2.1); K00600 glycine hydroxymethyltransferase
[EC:2.1.2.1]
Length=470
Score = 196 bits (497), Expect = 4e-50, Method: Compositional matrix adjust.
Identities = 95/147 (64%), Positives = 112/147 (76%), Gaps = 1/147 (0%)
Query 5 LKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYYGG 64
L DPE+Y L+ KEK RQ IELIA+ENF S AV E LGSCLTNKYSEG G RYYGG
Sbjct 12 LDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGG 71
Query 65 MEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGLND 124
EF+D+IE+LC R+ EAF +PE+W VNVQP+SGSPANFA ALLQPHDR MGL L
Sbjct 72 TEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPS 131
Query 125 GGHLTHGAYTP-SRRISATSLFYESLP 150
GGH+THG Y+ + ISATS+++E+LP
Sbjct 132 GGHITHGYYSSGGKNISATSIYFENLP 158
> dre:100144628 shmt2; serine hydroxymethyltransferase 2 (mitochondrial)
(EC:2.1.2.1); K00600 glycine hydroxymethyltransferase
[EC:2.1.2.1]
Length=492
Score = 195 bits (496), Expect = 5e-50, Method: Compositional matrix adjust.
Identities = 95/148 (64%), Positives = 111/148 (75%), Gaps = 0/148 (0%)
Query 3 QPLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYY 62
+ L + DPE++ LL KEK+RQ +ELIASENF S A E GSCL NKYSEG G RYY
Sbjct 36 ESLSQDDPEMWDLLLKEKDRQCRGLELIASENFCSRAALEAQGSCLNNKYSEGYPGKRYY 95
Query 63 GGMEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGL 122
GG E VDQIE LC +RA EAF LDP+ W VNVQP+SGSPANFA A+L PH+R MGL L
Sbjct 96 GGAEVVDQIELLCQKRALEAFDLDPQLWGVNVQPYSGSPANFAAYTAVLNPHERIMGLDL 155
Query 123 NDGGHLTHGAYTPSRRISATSLFYESLP 150
DGGHLTHG + RRISATS+++ES+P
Sbjct 156 PDGGHLTHGYMSDVRRISATSIYFESMP 183
> ath:AT4G32520 SHM3; SHM3 (SERINE HYDROXYMETHYLTRANSFERASE 3);
catalytic/ glycine hydroxymethyltransferase/ pyridoxal phosphate
binding (EC:2.1.2.1); K00600 glycine hydroxymethyltransferase
[EC:2.1.2.1]
Length=529
Score = 194 bits (494), Expect = 8e-50, Method: Compositional matrix adjust.
Identities = 91/146 (62%), Positives = 108/146 (73%), Gaps = 0/146 (0%)
Query 5 LKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYYGG 64
L E DPE+ ++ KEK+RQ +ELIASENF S AV E +GSCLTNKYSEG G RYYGG
Sbjct 83 LGEVDPEVRTIITKEKDRQFRSLELIASENFTSRAVMEAVGSCLTNKYSEGLPGKRYYGG 142
Query 65 MEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGLND 124
E++DQ+E LC RA AF LD +W VNVQP SGSPANFAV A+L PHDR MGL L
Sbjct 143 NEYIDQLETLCQNRALAAFRLDSTKWGVNVQPLSGSPANFAVYTAILSPHDRIMGLDLPH 202
Query 125 GGHLTHGAYTPSRRISATSLFYESLP 150
GGHL+HG T RR+S TS+++ES+P
Sbjct 203 GGHLSHGFMTAKRRVSGTSIYFESMP 228
> cel:C05D11.11 mel-32; Maternal Effect Lethal family member (mel-32);
K00600 glycine hydroxymethyltransferase [EC:2.1.2.1]
Length=507
Score = 191 bits (486), Expect = 8e-49, Method: Compositional matrix adjust.
Identities = 89/146 (60%), Positives = 113/146 (77%), Gaps = 0/146 (0%)
Query 5 LKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYYGG 64
+++ DPE++ ++ EK+RQ +ELIASENF S AV + LGS + NKYSEG GARYYGG
Sbjct 52 VEKVDPEVFDIMKNEKKRQRRGLELIASENFTSKAVMDALGSAMCNKYSEGYPGARYYGG 111
Query 65 MEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGLND 124
EF+DQ+E LC +RA E FGLDP +W VNVQP SGSPANFAV A++ + R MGL L D
Sbjct 112 NEFIDQMELLCQKRALEVFGLDPAKWGVNVQPLSGSPANFAVYTAIVGSNGRIMGLDLPD 171
Query 125 GGHLTHGAYTPSRRISATSLFYESLP 150
GGHLTHG +TP+R++SATS F++SLP
Sbjct 172 GGHLTHGFFTPARKVSATSEFFQSLP 197
> tpv:TP01_0390 serine hydroxymethyltransferase; K00600 glycine
hydroxymethyltransferase [EC:2.1.2.1]
Length=503
Score = 189 bits (481), Expect = 3e-48, Method: Compositional matrix adjust.
Identities = 92/146 (63%), Positives = 105/146 (71%), Gaps = 0/146 (0%)
Query 4 PLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYYG 63
PLKE DPE+Y LL +E++RQ I LIASEN+ S A E LGS TNKYSEG G RYYG
Sbjct 65 PLKEFDPEVYELLERERDRQRYSINLIASENYASRACMEALGSIFTNKYSEGLPGKRYYG 124
Query 64 GMEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGLN 123
G FVD IE LCI+R E FGL EEW VNVQP SGSPAN AV ALLQPHD+ MGL L
Sbjct 125 GCRFVDDIENLCIKRCLEVFGLSDEEWGVNVQPLSGSPANLAVYCALLQPHDKLMGLSLE 184
Query 124 DGGHLTHGAYTPSRRISATSLFYESL 149
GGHLTHG Y +++SA+S+F+ L
Sbjct 185 SGGHLTHGYYNAKKKVSASSIFFSPL 210
> ath:AT4G37930 SHM1; SHM1 (SERINE TRANSHYDROXYMETHYLTRANSFERASE
1); glycine hydroxymethyltransferase/ poly(U) binding (EC:2.1.2.1);
K00600 glycine hydroxymethyltransferase [EC:2.1.2.1]
Length=517
Score = 186 bits (471), Expect = 4e-47, Method: Compositional matrix adjust.
Identities = 86/147 (58%), Positives = 109/147 (74%), Gaps = 0/147 (0%)
Query 4 PLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYYG 63
PL+E DPE+ ++ EK RQ +ELI SENF S +V + +GS +TNKYSEG GARYYG
Sbjct 54 PLEEVDPEIADIIEHEKARQWKGLELIPSENFTSVSVMQAVGSVMTNKYSEGYPGARYYG 113
Query 64 GMEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGLN 123
G E++D E LC +RA EAF LDPE+W VNVQP SGSPANF V ALL+PH+R M L L
Sbjct 114 GNEYIDMAETLCQKRALEAFRLDPEKWGVNVQPLSGSPANFHVYTALLKPHERIMALDLP 173
Query 124 DGGHLTHGAYTPSRRISATSLFYESLP 150
GGHL+HG T +++ISA S+F+E++P
Sbjct 174 HGGHLSHGYQTDTKKISAVSIFFETMP 200
> ath:AT1G36370 SHM7; SHM7 (serine hydroxymethyltransferase 7);
catalytic/ glycine hydroxymethyltransferase/ pyridoxal phosphate
binding (EC:2.1.2.1); K00600 glycine hydroxymethyltransferase
[EC:2.1.2.1]
Length=598
Score = 178 bits (451), Expect = 1e-44, Method: Compositional matrix adjust.
Identities = 89/149 (59%), Positives = 111/149 (74%), Gaps = 1/149 (0%)
Query 3 QPLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYY 62
QP+ ADP+++ L+ KEK+RQV IELIASENFV AV E LGS LTNKYSEG GARYY
Sbjct 136 QPIHLADPDIHELMEKEKQRQVRGIELIASENFVCRAVMEALGSHLTNKYSEGMPGARYY 195
Query 63 GGMEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGL 122
G +++DQIE LCI+RA AFGL+ ++W VNVQP+S + ANFAV LL P +R MGL
Sbjct 196 TGNQYIDQIENLCIERALTAFGLESDKWGVNVQPYSCTSANFAVYTGLLLPGERIMGLDS 255
Query 123 NDGGHLTHGAYTP-SRRISATSLFYESLP 150
GGH++HG TP ++ISA S+F+ES P
Sbjct 256 PSGGHMSHGYCTPGGKKISAASIFFESFP 284
> ath:AT1G22020 SHM6; SHM6 (serine hydroxymethyltransferase 6);
catalytic/ glycine hydroxymethyltransferase/ pyridoxal phosphate
binding (EC:2.1.2.1); K00600 glycine hydroxymethyltransferase
[EC:2.1.2.1]
Length=599
Score = 176 bits (446), Expect = 3e-44, Method: Compositional matrix adjust.
Identities = 87/149 (58%), Positives = 109/149 (73%), Gaps = 1/149 (0%)
Query 3 QPLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYY 62
Q ++EADPE++ + KEK+RQ IELIASENFV AV E LGS LTNKYSEG GARYY
Sbjct 140 QSIEEADPEIHEFMEKEKQRQFRGIELIASENFVCRAVMEALGSHLTNKYSEGMPGARYY 199
Query 63 GGMEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGL 122
G +++DQIE LC +RA AFGL+ E+W VNVQP+S + ANFAV LL P +R MGL
Sbjct 200 TGNQYIDQIEILCQERALAAFGLNHEKWGVNVQPYSCTSANFAVFTGLLMPGERIMGLDS 259
Query 123 NDGGHLTHGAYTP-SRRISATSLFYESLP 150
GGH++HG YTP +++S S+F+ES P
Sbjct 260 PSGGHMSHGYYTPGGKKVSGASIFFESFP 288
> ath:AT5G26780 SHM2; SHM2 (SERINE HYDROXYMETHYLTRANSFERASE 2);
catalytic/ glycine hydroxymethyltransferase/ pyridoxal phosphate
binding (EC:2.1.2.1); K00600 glycine hydroxymethyltransferase
[EC:2.1.2.1]
Length=533
Score = 175 bits (443), Expect = 7e-44, Method: Compositional matrix adjust.
Identities = 83/146 (56%), Positives = 104/146 (71%), Gaps = 0/146 (0%)
Query 5 LKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYYGG 64
L E DPE+ ++ EK RQ ELI SENF S +V + +GS +TNKYSEG GARYYGG
Sbjct 55 LDEIDPEVADIIELEKARQWKGFELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGG 114
Query 65 MEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGLND 124
E++D E LC +RA EAF LDP +W VNVQ SGSPANF V ALL+PH+R M L L
Sbjct 115 NEYIDMAETLCQKRALEAFQLDPSKWGVNVQSLSGSPANFQVYTALLKPHERIMALDLPH 174
Query 125 GGHLTHGAYTPSRRISATSLFYESLP 150
GGHL+HG T +++ISA S+F+E++P
Sbjct 175 GGHLSHGYQTDTKKISAVSIFFETMP 200
> sce:YLR058C SHM2, SHMT2; Cytosolic serine hydroxymethyltransferase,
converts serine to glycine plus 5,10 methylenetetrahydrofolate;
major isoform involved in generating precursors
for purine, pyrimidine, amino acid, and lipid biosynthesis (EC:2.1.2.1);
K00600 glycine hydroxymethyltransferase [EC:2.1.2.1]
Length=469
Score = 172 bits (436), Expect = 5e-43, Method: Compositional matrix adjust.
Identities = 82/146 (56%), Positives = 108/146 (73%), Gaps = 0/146 (0%)
Query 5 LKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYYGG 64
L + DPE+ +++ E ERQ I+LIASENF ST+V + LG+ L+NKYSEG GARYYGG
Sbjct 17 LVDTDPEVDSIIKDEIERQKHSIDLIASENFTSTSVFDALGTPLSNKYSEGYPGARYYGG 76
Query 65 MEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGLND 124
E +D++E LC QRA +AF + P++W VNVQ SGSPAN V A+++PH+R MGL L D
Sbjct 77 NEHIDRMEILCQQRALKAFHVTPDKWGVNVQTLSGSPANLQVYQAIMKPHERLMGLYLPD 136
Query 125 GGHLTHGAYTPSRRISATSLFYESLP 150
GGHL+HG T +R+ISA S ++ES P
Sbjct 137 GGHLSHGYATENRKISAVSTYFESFP 162
> pfa:PFL1720w serine hydroxymethyltransferase (EC:2.1.2.1); K00600
glycine hydroxymethyltransferase [EC:2.1.2.1]
Length=442
Score = 163 bits (413), Expect = 2e-40, Method: Compositional matrix adjust.
Identities = 84/166 (50%), Positives = 111/166 (66%), Gaps = 3/166 (1%)
Query 3 QPLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYY 62
PL++ D EL+ LL KEK RQ++ I LIASEN +TAV+ECLG ++NKYSEG RYY
Sbjct 5 DPLQKYDKELFDLLEKEKNRQIETINLIASENLTNTAVRECLGDRISNKYSEGYPHKRYY 64
Query 63 GGMEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGL 122
GG ++VD+IE LC +RA EAF + EEW VNVQP SGS AN L AL+ + MG+ L
Sbjct 65 GGNDYVDKIEELCYKRALEAFNVSEEEWGVNVQPLSGSAANVQALYALVGVKGKIMGMHL 124
Query 123 NDGGHLTHGAYTPSRRISATSLFYES--LPCH-QGFVTWRNERFMA 165
GGHLTHG + +++S TS +ES C+ +G+V + R +A
Sbjct 125 CSGGHLTHGFFDEKKKVSITSDLFESKLYKCNSEGYVDMESVRNLA 170
> sce:YBR263W SHM1, SHMT1, TMP3; Mitochondrial serine hydroxymethyltransferase,
converts serine to glycine plus 5,10 methylenetetrahydrofolate;
involved in generating precursors for
purine, pyrimidine, amino acid, and lipid biosynthesis; reverse
reaction generates serine (EC:2.1.2.1); K00600 glycine hydroxymethyltransferase
[EC:2.1.2.1]
Length=490
Score = 161 bits (407), Expect = 1e-39, Method: Compositional matrix adjust.
Identities = 82/168 (48%), Positives = 108/168 (64%), Gaps = 5/168 (2%)
Query 3 QPLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYY 62
+P+ E DPE++ +L +E+ RQ I LI SENF S AV + LGS L NKYSEG G RYY
Sbjct 31 KPVSEGDPEMFDILQQERHRQKHSITLIPSENFTSKAVMDLLGSELQNKYSEGYPGERYY 90
Query 63 GGMEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGL 122
GG E +D+ E+LC RA E +GLDP +W VNVQP SG+PAN V A++ +R MGL L
Sbjct 91 GGNEIIDKSESLCQARALELYGLDPAKWGVNVQPLSGAPANLYVYSAIMNVGERLMGLDL 150
Query 123 NDGGHLTHGAYTPS-RRISATSLFYESLPCH----QGFVTWRNERFMA 165
DGGHL+HG S IS S +++S+P H G + + N + +A
Sbjct 151 PDGGHLSHGYQLKSGTPISFISKYFQSMPYHVDHTTGLIDYDNLQVLA 198
> cpv:cgd8_2610 cytosolic serine hydroxymethyl transferase ; K00600
glycine hydroxymethyltransferase [EC:2.1.2.1]
Length=445
Score = 145 bits (365), Expect = 8e-35, Method: Compositional matrix adjust.
Identities = 71/148 (47%), Positives = 101/148 (68%), Gaps = 4/148 (2%)
Query 3 QPLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYY 62
+ LKE DP +Y L+ +E +RQ++ +E+IASENFVS V + L S + ++ ++
Sbjct 7 KSLKELDPIMYELINEEYDRQINGLEMIASENFVSKGVLDSLSSTFSMFNNDKNMELNST 66
Query 63 GGMEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGL 122
E ++ L +RA +A+GLDPE W NV+PHSGSPANFAVL A+L+P+DR MGL L
Sbjct 67 SAQELLE----LTNERALKAYGLDPEVWGANVKPHSGSPANFAVLNAVLKPNDRIMGLSL 122
Query 123 NDGGHLTHGAYTPSRRISATSLFYESLP 150
GGHLTHG YT +R++ +S ++ESLP
Sbjct 123 QHGGHLTHGHYTNLKRVNCSSHYFESLP 150
> eco:b2551 glyA, ECK2548, JW2535; serine hydroxymethyltransferase
(EC:2.1.2.1); K00600 glycine hydroxymethyltransferase [EC:2.1.2.1]
Length=417
Score = 139 bits (349), Expect = 6e-33, Method: Compositional matrix adjust.
Identities = 72/128 (56%), Positives = 88/128 (68%), Gaps = 4/128 (3%)
Query 5 LKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARYYGG 64
+ + D EL+ + +EK RQ + IELIASEN+ S V + GS LTNKY+EG G RYYGG
Sbjct 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 67
Query 65 MEFVDQIEALCIQRAKEAFGLDPEEWHVNVQPHSGSPANFAVLMALLQPHDRFMGLGLND 124
E+VD +E L I RAKE FG D + NVQPHSGS ANFAV ALL+P D +G+ L
Sbjct 68 CEYVDIVEQLAIDRAKELFGAD----YANVQPHSGSQANFAVYTALLEPGDTVLGMNLAH 123
Query 125 GGHLTHGA 132
GGHLTHG+
Sbjct 124 GGHLTHGS 131
> cpv:cgd8_2580 mitochondrial serine hydroxymethyl transferase
Length=438
Score = 101 bits (252), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 53/120 (44%), Positives = 70/120 (58%), Gaps = 3/120 (2%)
Query 2 MQPLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGARY 61
M E+D EL+ ++ KEK+ Q + L EN + A ++ LGS LTNKYSEG G RY
Sbjct 1 MNTTIESDQELFNIINKEKDFQNSHLNLHPKENVMINAARKVLGSILTNKYSEGFPGTRY 60
Query 62 YGGMEFVDQIEALCIQRAKEAFGLDP---EEWHVNVQPHSGSPANFAVLMALLQPHDRFM 118
YGG +D+IE LC R K+ LD +EW N+Q +SGS A A+ M LL DR +
Sbjct 61 YGGTHVIDKIETLCASRLKQFLKLDKKSNDEWLFNIQCYSGSHAELAICMGLLNKGDRIL 120
> hsa:10129 FRY, 13CDNA73, 214K23.2, C13orf14, CG003, bA207N4.2,
bA37E23.1; furry homolog (Drosophila)
Length=3013
Score = 32.3 bits (72), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 26/114 (22%), Positives = 53/114 (46%), Gaps = 20/114 (17%)
Query 1 CMQPLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGAR 60
C+ LK DP++ A +A E ++ + +I + +TA Q L + +T + +GS G
Sbjct 388 CLSNLKNKDPKM-ARVALESLYRLLWVYMIRIKCESNTATQSRLITIITTLFPKGSRGVV 446
Query 61 --------YYGGMEFVDQ-----------IEALCIQRAKEAFGLDPEEWHVNVQ 95
+ ++F+ Q + LC+ + +AF L+PE ++ ++
Sbjct 447 PRDMPLNIFVKIIQFIAQERLDFAMKEIIFDFLCVGKPAKAFSLNPERMNIGLR 500
> mmu:98303 D630023F18Rik, AI314969; RIKEN cDNA D630023F18 gene
Length=231
Score = 32.0 bits (71), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 13/37 (35%), Positives = 19/37 (51%), Gaps = 0/37 (0%)
Query 124 DGGHLTHGAYTPSRRISATSLFYESLPCHQGFVTWRN 160
+G + G +TP+ IS T + + P H V WRN
Sbjct 182 NGDPVGKGTHTPATNISPTPVLSSAQPFHSSTVMWRN 218
> xla:100126659 fry; furry homolog
Length=3010
Score = 31.6 bits (70), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 25/114 (21%), Positives = 53/114 (46%), Gaps = 20/114 (17%)
Query 1 CMQPLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGAR 60
C+ LK DP++ A +A E ++ + +I + +TA Q L + + + +G G
Sbjct 388 CLSNLKNKDPKM-ARVALESLYRLLWVYMIRIKCESNTATQSRLTTIVGTLFPKGPRGVV 446
Query 61 --------YYGGMEFVDQI-----------EALCIQRAKEAFGLDPEEWHVNVQ 95
+ ++F+ Q+ + LC+ +A +AF L+PE ++ ++
Sbjct 447 PRDMPLNIFVKIIQFIAQVKLDFAMKEIIFDLLCVGKAAKAFSLNPERMNIGLR 500
> mmu:320365 Fry, 13CDNA73, 9330186A19Rik, AF346502, AI462658,
C87180, D930046M03, KIAA4143, cg003, mKIAA4143; furry homolog
(Drosophila)
Length=3020
Score = 31.2 bits (69), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 26/114 (22%), Positives = 52/114 (45%), Gaps = 20/114 (17%)
Query 1 CMQPLKEADPELYALLAKEKERQVDCIELIASENFVSTAVQECLGSCLTNKYSEGSVGAR 60
C+ LK DP++ A +A E ++ + +I + +TA Q L + T + +GS G
Sbjct 388 CLSNLKNKDPKM-ARVALESLYRLLWVYMIRIKCESNTATQSRLITITTTLFPKGSRGVV 446
Query 61 --------YYGGMEFVDQ-----------IEALCIQRAKEAFGLDPEEWHVNVQ 95
+ ++F+ Q + LC+ + +AF L+PE ++ ++
Sbjct 447 PRDMPLNIFVKIIQFIAQERLDFAMKEIIFDFLCVGKPAKAFSLNPERMNIGLR 500
> dre:100034467 si:ch211-132b12.1
Length=586
Score = 29.6 bits (65), Expect = 5.4, Method: Compositional matrix adjust.
Identities = 20/85 (23%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
Query 3 QPLKEADPELY----ALLAKEKERQVDCIELIASEN-FVSTAVQECLGSCLTNKYSEGSV 57
+P + ADP+++ + V I ++AS N + + ++CLG CL N +
Sbjct 249 EPARLADPQVWLEAGTQILFSYSVSVGSITVLASYNKYHNNCYRDCLGLCLLNSVTSFVA 308
Query 58 GARYYGGMEFVDQIEALCIQRAKEA 82
G + + F+ Q + + I+ E+
Sbjct 309 GFAVFTVLGFMAQEQGVPIEEVAES 333
Lambda K H
0.320 0.135 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 4406352944
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
Posted date: Sep 17, 2011 2:57 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40