bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
164,496 sequences; 82,071,388 total letters
Query= Eten_1716_orf4
Length=195
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_086470 cAMP-dependent protein kinase catalytic subu... 342 4e-94
tgo:TGME49_026030 cAMP-dependent protein kinase catalytic subu... 258 1e-68
dre:561941 protein kinase, X-linked-like; K04345 protein kinas... 257 2e-68
hsa:5613 PRKX, PKX1; protein kinase, X-linked (EC:2.7.11.1); K... 253 2e-67
cpv:cgd3_3040 protein kinase, cAMP-dependent, catalytic chain ... 249 4e-66
mmu:19108 Prkx, PKX1, Pkare; protein kinase, X-linked (EC:2.7.... 247 2e-65
mmu:18747 Prkaca, Cs, PKA, PKCD, Pkaca; protein kinase, cAMP d... 243 3e-64
dre:564064 prkacaa, zgc:158799; protein kinase, cAMP-dependent... 243 3e-64
hsa:5566 PRKACA, MGC102831, MGC48865, PKACA; protein kinase, c... 243 4e-64
xla:380388 prkacb, MGC53163, XPKAbeta, kin-1, pkacb, prkacba; ... 243 4e-64
dre:445076 prkacab, zgc:91856; protein kinase, cAMP-dependent,... 241 1e-63
hsa:5567 PRKACB, DKFZp781I2452, MGC41879, MGC9320, PKACB; prot... 241 1e-63
xla:100101276 prkaca; protein kinase, cAMP-dependent, catalyti... 241 1e-63
tgo:TGME49_028420 cAMP-dependent protein kinase catalytic subu... 241 1e-63
xla:446502 prkacbb, MGC80071; protein kinase, cAMP-dependent, ... 241 1e-63
cel:ZK909.2 kin-1; protein KINase family member (kin-1); K0434... 241 1e-63
mmu:18749 Prkacb, Pkacb; protein kinase, cAMP dependent, catal... 241 1e-63
dre:563147 prkacbb, MGC110804, prkacb, wu:fz54b03, zgc:110804;... 240 2e-63
dre:393998 prkacba, MGC64054, Prkacb, zgc:64054; protein kinas... 239 5e-63
cel:F47F2.1 hypothetical protein; K04345 protein kinase A [EC:... 236 4e-62
sce:YPL203W TPK2, PKA2, PKA3, YKR1; Tpk2p (EC:2.7.11.11); K043... 236 5e-62
tpv:TP02_0378 cAMP-dependent protein kinase; K04345 protein ki... 233 4e-61
bbo:BBOV_III005740 17.m07511; protein kinase domain containing... 232 8e-61
sce:YKL166C TPK3; Tpk3p (EC:2.7.11.11); K04345 protein kinase ... 228 9e-60
sce:YJL164C TPK1, PKA1, SRA3; Tpk1p (EC:2.7.11.11); K04345 pro... 228 1e-59
hsa:5568 PRKACG, KAPG, PKACg; protein kinase, cAMP-dependent, ... 226 3e-59
pfa:PFI1685w PfPKAc, PfPKA, PKA; cAMP-dependent protein kinase... 221 1e-57
bbo:BBOV_I004190 19.m02221; cAMP-dependent protein kinase (EC:... 219 5e-57
tpv:TP02_0727 cAMP-dependent protein kinase catalytic subunit;... 200 3e-51
pfa:PFL2250c PKB; rac-beta serine/threonine protein kinase, Pf... 197 3e-50
pfa:PF14_0346 PKG; cGMP-dependent protein kinase (EC:2.7.11.12... 192 6e-49
bbo:BBOV_I004690 19.m02237; cGMP dependent protein kinase (EC:... 192 8e-49
cel:T01H8.1 rskn-1; RSK-pNinety (RSK-p90 kinase) homolog famil... 190 2e-48
tgo:TGME49_111360 cGMP-dependent protein kinase, putative (EC:... 190 2e-48
tgo:TGME49_067540 protein kinase, putative (EC:4.1.1.70 2.7.11... 190 3e-48
dre:100125912 prkg2; protein kinase, cGMP-dependent, type II (... 189 6e-48
cel:R04A9.7 hypothetical protein; K04688 p70 ribosomal S6 kina... 189 6e-48
hsa:5593 PRKG2, PRKGR2, cGKII; protein kinase, cGMP-dependent,... 188 8e-48
cel:Y47D3A.16 rsks-1; RSK-pSeventy (RSK-p70 kinase) homolog fa... 188 9e-48
dre:406349 rps6kb1b, fc51h01, rps6kb1, wu:fc51h01, zgc:55713; ... 188 1e-47
mmu:19092 Prkg2, AW212535, CGKII, MGC130517, Prkgr2, cGK-II; p... 187 1e-47
cpv:cgd8_750 cyclic nucleotide (cGMP)-dependent protein kinase... 187 1e-47
dre:562242 ribosomal protein S6 kinase b, polypeptide 1-like; ... 187 2e-47
xla:394276 rps6kb1, p70-alpha, p70-s6k, p70s6k, ps6k, rps6kb1-... 186 6e-47
mmu:72508 Rps6kb1, 2610318I15Rik, 4732464A07Rik, 70kDa, AA9597... 185 7e-47
hsa:6198 RPS6KB1, PS6K, S6K, S6K1, STK14A, p70(S6K)-alpha, p70... 185 7e-47
hsa:6199 RPS6KB2, KLS, P70-beta, P70-beta-1, P70-beta-2, S6K-b... 185 7e-47
mmu:58988 Rps6kb2, 70kDa, S6K2; ribosomal protein S6 kinase, p... 185 7e-47
dre:566430 cGMP dependent protein kinase I 185 1e-46
mmu:19091 Prkg1, AW125416, CGKI, MGC132849, Prkg1b, Prkgr1b; p... 183 3e-46
> tgo:TGME49_086470 cAMP-dependent protein kinase catalytic subunit
(EC:2.7.11.11); K04345 protein kinase A [EC:2.7.11.11]
Length=514
Score = 342 bits (877), Expect = 4e-94, Method: Compositional matrix adjust.
Identities = 159/195 (81%), Positives = 178/195 (91%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
++ MKQVEHVKDE+RIL+ + HPFIVNLLA+FQDEKRLF+LMEYVNGGELFS+LR++ +
Sbjct 240 IVKMKQVEHVKDEKRILSSIEHPFIVNLLAAFQDEKRLFILMEYVNGGELFSHLRRRNCI 299
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
+QARLY AEITLAF+YLH+R IVYRDLKPENLL+D+QGHIKITDFGFAKVV RTWTL
Sbjct 300 PTDQARLYAAEITLAFQYLHQRHIVYRDLKPENLLIDSQGHIKITDFGFAKVVKDRTWTL 359
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGTHEYLAPESITRRGHGL VDWWALGILLFEMLAG PPFVD+ PLGIY+KIIAGKIEFP
Sbjct 360 CGTHEYLAPESITRRGHGLPVDWWALGILLFEMLAGHPPFVDENPLGIYRKIIAGKIEFP 419
Query 181 PLFDSAAKSLVRRLL 195
FD AAKSLV+RLL
Sbjct 420 RSFDYAAKSLVKRLL 434
> tgo:TGME49_026030 cAMP-dependent protein kinase catalytic subunit,
putative (EC:2.7.11.11); K04345 protein kinase A [EC:2.7.11.11]
Length=343
Score = 258 bits (658), Expect = 1e-68, Method: Compositional matrix adjust.
Identities = 114/195 (58%), Positives = 153/195 (78%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
VI KQV+H+ E+RIL ++HPF VN+L +F+D++ L+++MEYV GGE F+ LRK
Sbjct 72 VIRQKQVDHILSEKRILQMINHPFTVNMLGTFKDDRYLYIVMEYVIGGEFFTLLRKTRRF 131
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
+ AR Y A++TL FEYLH+R+I+YRDLKPENLL+DA+G++K+TDFGFAKV+ RT+TL
Sbjct 132 ENDAARFYAAQVTLIFEYLHDRNIIYRDLKPENLLVDAEGYLKLTDFGFAKVIEYRTYTL 191
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EY+APE + +GHG VDWW LGIL++EM+ G PPF DD P+G+Y+KI+ G+I FP
Sbjct 192 CGTPEYIAPEVLLNKGHGKPVDWWTLGILIYEMILGYPPFFDDEPMGVYQKILGGRIAFP 251
Query 181 PLFDSAAKSLVRRLL 195
FD AK LV+RLL
Sbjct 252 KFFDKNAKLLVKRLL 266
> dre:561941 protein kinase, X-linked-like; K04345 protein kinase
A [EC:2.7.11.11]
Length=357
Score = 257 bits (656), Expect = 2e-68, Method: Compositional matrix adjust.
Identities = 116/195 (59%), Positives = 148/195 (75%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
VI +KQ +HV +E+ +L +++HPF+V L + D++ L++LMEYVNGGELFSYLR +
Sbjct 84 VIRLKQEQHVHNEKEVLTEVNHPFLVRLFWTHHDDRFLYMLMEYVNGGELFSYLRSRGHF 143
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
S Y AEI A EYLH + IVYRDLKPEN+LLD++GHI++TDFGFAK ++ RTWTL
Sbjct 144 SNSTGMFYSAEIVCAIEYLHSKEIVYRDLKPENILLDSEGHIRLTDFGFAKKLSERTWTL 203
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EYLAPE I +GHG VDWWALG+L+FEMLAG PPF DD P GIY+KI+AGK+EFP
Sbjct 204 CGTPEYLAPEVIQSKGHGRAVDWWALGVLIFEMLAGYPPFFDDNPFGIYQKILAGKLEFP 263
Query 181 PLFDSAAKSLVRRLL 195
D K L+++ L
Sbjct 264 RHLDLYVKDLIKKFL 278
> hsa:5613 PRKX, PKX1; protein kinase, X-linked (EC:2.7.11.1);
K04345 protein kinase A [EC:2.7.11.11]
Length=358
Score = 253 bits (647), Expect = 2e-67, Method: Compositional matrix adjust.
Identities = 118/195 (60%), Positives = 146/195 (74%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
VI +KQ +HV +E+ +L ++SHPF++ L ++ DE+ L++LMEYV GGELFSYLR +
Sbjct 85 VIRLKQEQHVHNEKSVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRF 144
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
S Y AEI A EYLH + IVYRDLKPEN+LLD GHIK+TDFGFAK + RTWTL
Sbjct 145 SSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTL 204
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EYLAPE I +GHG VDWWALGIL+FEML+G PPF DD P GIY+KI+AGKI+FP
Sbjct 205 CGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFP 264
Query 181 PLFDSAAKSLVRRLL 195
D K L+++LL
Sbjct 265 RHLDFHVKDLIKKLL 279
> cpv:cgd3_3040 protein kinase, cAMP-dependent, catalytic chain
; K04345 protein kinase A [EC:2.7.11.11]
Length=392
Score = 249 bits (636), Expect = 4e-66, Method: Compositional matrix adjust.
Identities = 108/195 (55%), Positives = 150/195 (76%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
VI KQV+H+ +E+ IL+++ HPF+V + +F+D++ L+++ME+V GGE F+YLR+
Sbjct 121 VIRQKQVDHITNEKAILSRIKHPFLVRMFGTFKDDRYLYIMMEFVIGGEFFTYLRRCRHF 180
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
E +R Y A++ L FEYLH ++I+YRDLKPEN+L+D G++K+TDFGFAK + RT+TL
Sbjct 181 DNETSRFYAAQVVLMFEYLHGKNIIYRDLKPENILIDKDGYLKLTDFGFAKAIEYRTFTL 240
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EY+APE + +GHG VDWW LGIL++EM+ G PPF DD P+GIY+KI+AGKI FP
Sbjct 241 CGTPEYIAPEVLLNKGHGKPVDWWTLGILIYEMVVGFPPFYDDEPMGIYQKILAGKIFFP 300
Query 181 PLFDSAAKSLVRRLL 195
FD KSLV+RLL
Sbjct 301 KYFDKNCKSLVKRLL 315
> mmu:19108 Prkx, PKX1, Pkare; protein kinase, X-linked (EC:2.7.11.1);
K04345 protein kinase A [EC:2.7.11.11]
Length=355
Score = 247 bits (630), Expect = 2e-65, Method: Compositional matrix adjust.
Identities = 113/195 (57%), Positives = 147/195 (75%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
VI +KQ +HV++E+ +L +++HPF++ LL + D + L++LME+V GGELF+YLR +
Sbjct 82 VIRLKQEQHVQNEKAVLKEINHPFLIKLLWTGHDNRFLYMLMEFVPGGELFTYLRNRGRF 141
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
S + Y EI A EYLH + IVYRDLKPEN+LLD +GHIK+TDFGFAK + RTWTL
Sbjct 142 SSVASVFYATEIVCAIEYLHSKEIVYRDLKPENILLDREGHIKLTDFGFAKKLVDRTWTL 201
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EYLAPE I +GHG VDWWALGIL+FEML+G PPF DD P GIY+KI+A KI+FP
Sbjct 202 CGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILACKIDFP 261
Query 181 PLFDSAAKSLVRRLL 195
D +K L+++LL
Sbjct 262 RQLDFTSKDLIKKLL 276
> mmu:18747 Prkaca, Cs, PKA, PKCD, Pkaca; protein kinase, cAMP
dependent, catalytic, alpha (EC:2.7.11.11); K04345 protein
kinase A [EC:2.7.11.11]
Length=351
Score = 243 bits (620), Expect = 3e-64, Method: Compositional matrix adjust.
Identities = 111/195 (56%), Positives = 144/195 (73%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
V+ +KQ+EH +E+RIL ++ PF+V L SF+D L+++MEYV GGE+FS+LR+
Sbjct 80 VVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRF 139
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
S AR Y A+I L FEYLH ++YRDLKPENLL+D QG+I++TDFGFAK V GRTWTL
Sbjct 140 SEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTL 199
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++GK+ FP
Sbjct 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 259
Query 181 PLFDSAAKSLVRRLL 195
F S K L+R LL
Sbjct 260 SHFSSDLKDLLRNLL 274
> dre:564064 prkacaa, zgc:158799; protein kinase, cAMP-dependent,
catalytic, alpha, genome duplicate a (EC:2.7.11.11); K04345
protein kinase A [EC:2.7.11.11]
Length=352
Score = 243 bits (620), Expect = 3e-64, Method: Compositional matrix adjust.
Identities = 112/195 (57%), Positives = 144/195 (73%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
V+ +KQ+EH +E+RIL +S PF+V L SF+D L+++MEYV GGE+FS+LR+
Sbjct 81 VVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNTNLYMVMEYVPGGEMFSHLRRIGRF 140
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
S AR Y A+I L FEYLH ++YRDLKPENLL+D QG+I++TDFGFAK V GRTWTL
Sbjct 141 SEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTL 200
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++GK+ FP
Sbjct 201 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 260
Query 181 PLFDSAAKSLVRRLL 195
F S K L+R LL
Sbjct 261 SHFSSDLKDLLRNLL 275
> hsa:5566 PRKACA, MGC102831, MGC48865, PKACA; protein kinase,
cAMP-dependent, catalytic, alpha (EC:2.7.11.11); K04345 protein
kinase A [EC:2.7.11.11]
Length=351
Score = 243 bits (619), Expect = 4e-64, Method: Compositional matrix adjust.
Identities = 111/195 (56%), Positives = 144/195 (73%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
V+ +KQ+EH +E+RIL ++ PF+V L SF+D L+++MEYV GGE+FS+LR+
Sbjct 80 VVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRF 139
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
S AR Y A+I L FEYLH ++YRDLKPENLL+D QG+I++TDFGFAK V GRTWTL
Sbjct 140 SEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTL 199
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++GK+ FP
Sbjct 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 259
Query 181 PLFDSAAKSLVRRLL 195
F S K L+R LL
Sbjct 260 SHFSSDLKDLLRNLL 274
> xla:380388 prkacb, MGC53163, XPKAbeta, kin-1, pkacb, prkacba;
protein kinase, cAMP-dependent, catalytic, beta; K04345 protein
kinase A [EC:2.7.11.11]
Length=351
Score = 243 bits (619), Expect = 4e-64, Method: Compositional matrix adjust.
Identities = 111/195 (56%), Positives = 144/195 (73%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
V+ +KQ+EH +E+RIL ++ PF+V L SF+D L+++MEYV GGE+FS+LR+
Sbjct 80 VVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMIMEYVPGGEMFSHLRRIGRF 139
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
S AR Y A+I L FEYLH ++YRDLKPENLL+D QG+I++TDFGFAK V GRTWTL
Sbjct 140 SEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTL 199
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++GK+ FP
Sbjct 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 259
Query 181 PLFDSAAKSLVRRLL 195
F S K L+R LL
Sbjct 260 SHFSSDLKDLLRNLL 274
> dre:445076 prkacab, zgc:91856; protein kinase, cAMP-dependent,
catalytic, alpha, genome duplicate b (EC:2.7.11.11); K04345
protein kinase A [EC:2.7.11.11]
Length=351
Score = 241 bits (616), Expect = 1e-63, Method: Compositional matrix adjust.
Identities = 110/195 (56%), Positives = 144/195 (73%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
V+ +KQ+EH +E+RIL +S PF+V L SF+D L+++M+YV GGE+FS+LR+
Sbjct 80 VVKLKQIEHTLNEKRILQAVSFPFLVRLEYSFKDNTNLYMVMQYVQGGEMFSHLRRIGRF 139
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
S AR Y ++I L FEYLH ++YRDLKPENLL+D QG+I++TDFGFAK V GRTWTL
Sbjct 140 SEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTL 199
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++GK+ FP
Sbjct 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLMYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 259
Query 181 PLFDSAAKSLVRRLL 195
F S K L+R LL
Sbjct 260 SHFSSDLKDLLRNLL 274
> hsa:5567 PRKACB, DKFZp781I2452, MGC41879, MGC9320, PKACB; protein
kinase, cAMP-dependent, catalytic, beta (EC:2.7.11.11);
K04345 protein kinase A [EC:2.7.11.11]
Length=351
Score = 241 bits (615), Expect = 1e-63, Method: Compositional matrix adjust.
Identities = 110/195 (56%), Positives = 144/195 (73%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
V+ +KQ+EH +E+RIL ++ PF+V L +F+D L+++MEYV GGE+FS+LR+
Sbjct 80 VVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRF 139
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
S AR Y A+I L FEYLH ++YRDLKPENLL+D QG+I++TDFGFAK V GRTWTL
Sbjct 140 SEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTL 199
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++GK+ FP
Sbjct 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 259
Query 181 PLFDSAAKSLVRRLL 195
F S K L+R LL
Sbjct 260 SHFSSDLKDLLRNLL 274
> xla:100101276 prkaca; protein kinase, cAMP-dependent, catalytic,
alpha (EC:2.7.11.1); K04345 protein kinase A [EC:2.7.11.11]
Length=351
Score = 241 bits (615), Expect = 1e-63, Method: Compositional matrix adjust.
Identities = 110/195 (56%), Positives = 144/195 (73%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
V+ +KQ+EH +E+RIL ++ PF+V L SF+D L+++MEYV GGE+FS+LR+
Sbjct 80 VVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNTNLYMVMEYVAGGEMFSHLRRIGRF 139
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
S AR Y ++I L FEYLH ++YRDLKPENLL+D QG+I++TDFGFAK V GRTWTL
Sbjct 140 SEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTL 199
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++GK+ FP
Sbjct 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 259
Query 181 PLFDSAAKSLVRRLL 195
F S K L+R LL
Sbjct 260 SHFSSDLKDLLRNLL 274
> tgo:TGME49_028420 cAMP-dependent protein kinase catalytic subunit,
putative (EC:2.7.11.11); K04345 protein kinase A [EC:2.7.11.11]
Length=333
Score = 241 bits (615), Expect = 1e-63, Method: Compositional matrix adjust.
Identities = 110/195 (56%), Positives = 143/195 (73%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
+I +K V+H+ +E++IL L HP V SFQD + L+L+ME V GGE F++LRK
Sbjct 62 IIKLKHVDHIINEKKILLALDHPLTVRCFGSFQDSRYLYLVMELVPGGEFFTHLRKAKRF 121
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
+ AR Y A+I F+YLH ++I+YRDLKPEN+LLD G++K+TDFGFAKVV RT TL
Sbjct 122 DNDTARFYAAQIVDIFDYLHSQNIIYRDLKPENMLLDKDGYVKLTDFGFAKVVEFRTDTL 181
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EY+APE + +GHG VDWW LGIL++EM+ G PPF+DD PLGIY+KI+AGK FP
Sbjct 182 CGTPEYIAPEVLLNKGHGKPVDWWTLGILIYEMMVGYPPFLDDDPLGIYQKILAGKFVFP 241
Query 181 PLFDSAAKSLVRRLL 195
FD AK LV++LL
Sbjct 242 KFFDKDAKVLVKKLL 256
> xla:446502 prkacbb, MGC80071; protein kinase, cAMP-dependent,
catalytic, beta b; K04345 protein kinase A [EC:2.7.11.11]
Length=351
Score = 241 bits (615), Expect = 1e-63, Method: Compositional matrix adjust.
Identities = 110/195 (56%), Positives = 144/195 (73%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
V+ +KQ+EH +E+RIL ++ PF+V L SF+D L+++MEYV GGE+FS+LR+
Sbjct 80 VVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRF 139
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
S AR Y ++I L FEYLH ++YRDLKPENLL+D QG+I++TDFGFAK V GRTWTL
Sbjct 140 SEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTL 199
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++GK+ FP
Sbjct 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 259
Query 181 PLFDSAAKSLVRRLL 195
F S K L+R LL
Sbjct 260 SHFSSDLKDLLRNLL 274
> cel:ZK909.2 kin-1; protein KINase family member (kin-1); K04345
protein kinase A [EC:2.7.11.11]
Length=381
Score = 241 bits (615), Expect = 1e-63, Method: Compositional matrix adjust.
Identities = 107/195 (54%), Positives = 147/195 (75%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
V+ +KQVEH +E+RIL + PF+VN+ SF+D L++++E+++GGE+FS+LR+
Sbjct 110 VVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRF 169
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
S +R Y A+I LAFEYLH ++YRDLKPENLL+D+ G++KITDFGFAK V GRTWTL
Sbjct 170 SEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTL 229
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++GK++FP
Sbjct 230 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFP 289
Query 181 PLFDSAAKSLVRRLL 195
F + K L++ LL
Sbjct 290 SHFSNELKDLLKNLL 304
> mmu:18749 Prkacb, Pkacb; protein kinase, cAMP dependent, catalytic,
beta (EC:2.7.11.11); K04345 protein kinase A [EC:2.7.11.11]
Length=338
Score = 241 bits (614), Expect = 1e-63, Method: Compositional matrix adjust.
Identities = 111/195 (56%), Positives = 143/195 (73%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
V+ +KQ+EH +E+RIL + PF+V L SF+D L+++MEYV GGE+FS+LR+
Sbjct 67 VVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRF 126
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
S AR Y A+I L FEYLH ++YRDLKPENLL+D QG+I++TDFGFAK V GRTWTL
Sbjct 127 SEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTL 186
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++GK+ FP
Sbjct 187 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 246
Query 181 PLFDSAAKSLVRRLL 195
F S K L+R LL
Sbjct 247 SHFSSDLKDLLRNLL 261
> dre:563147 prkacbb, MGC110804, prkacb, wu:fz54b03, zgc:110804;
protein kinase, cAMP-dependent, catalytic, beta b; K04345
protein kinase A [EC:2.7.11.11]
Length=351
Score = 240 bits (613), Expect = 2e-63, Method: Compositional matrix adjust.
Identities = 111/195 (56%), Positives = 143/195 (73%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
V+ +KQVEH +E+RIL +S PF+V L +F+D L+++MEYV GGE+FS+LR+
Sbjct 80 VVKLKQVEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRF 139
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
S AR Y A+I L FEYLH ++YRDLKPENLL+D G+I++TDFGFAK V GRTWTL
Sbjct 140 SEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTL 199
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++GK+ FP
Sbjct 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 259
Query 181 PLFDSAAKSLVRRLL 195
F S K L+R LL
Sbjct 260 SHFSSDLKDLLRNLL 274
> dre:393998 prkacba, MGC64054, Prkacb, zgc:64054; protein kinase,
cAMP-dependent, catalytic, beta a; K04345 protein kinase
A [EC:2.7.11.11]
Length=395
Score = 239 bits (609), Expect = 5e-63, Method: Compositional matrix adjust.
Identities = 107/195 (54%), Positives = 144/195 (73%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
V+ +KQ+EH +E++IL +S PF+V L +F+D L+++M Y+ GGE+FS+LR+
Sbjct 124 VVKLKQIEHTLNEKKILQAVSFPFLVKLECAFKDNSNLYMVMRYIQGGEMFSHLRRIGRF 183
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
S + AR Y A+I L FEYLH ++YRDLKPENLL+D QG+I++TDFGFAK V GRTWTL
Sbjct 184 SEQNARFYAAQIVLTFEYLHMLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTL 243
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++GK+ +P
Sbjct 244 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRYP 303
Query 181 PLFDSAAKSLVRRLL 195
F S K L+R LL
Sbjct 304 SHFSSDLKDLLRNLL 318
> cel:F47F2.1 hypothetical protein; K04345 protein kinase A [EC:2.7.11.11]
Length=398
Score = 236 bits (601), Expect = 4e-62, Method: Compositional matrix adjust.
Identities = 109/195 (55%), Positives = 141/195 (72%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
V+ M+Q +HV +E+R+L QL HPFIV + AS +D L+++ME+V GGE+FSYLR S
Sbjct 126 VVDMRQTQHVHNEKRVLLQLKHPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSF 185
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
S AR Y +EI A EY+H IVYRDLKPENL+L +GHIK+ DFGFAK + RT+T+
Sbjct 186 SNSMARFYASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAKELRDRTYTI 245
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT +YLAPES+ R GH VDWWALGIL++EM+ G+PPF T IY II K++FP
Sbjct 246 CGTPDYLAPESLARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDAIIEHKLKFP 305
Query 181 PLFDSAAKSLVRRLL 195
F+ AAK LV++LL
Sbjct 306 RSFNLAAKDLVKKLL 320
> sce:YPL203W TPK2, PKA2, PKA3, YKR1; Tpk2p (EC:2.7.11.11); K04345
protein kinase A [EC:2.7.11.11]
Length=380
Score = 236 bits (601), Expect = 5e-62, Method: Compositional matrix adjust.
Identities = 105/195 (53%), Positives = 139/195 (71%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
V+ MKQVEH DERR+L + HPF++ + +FQD + +F++M+Y+ GGELFS LRK
Sbjct 106 VVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRF 165
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
A+ Y AE+ LA EYLH +I+YRDLKPEN+LLD GHIKITDFGFAK V TWTL
Sbjct 166 PNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTL 225
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT +Y+APE IT + + VDWW+LG+L++EMLAG PF D TP+ Y+KI+ GK+ +P
Sbjct 226 CGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYP 285
Query 181 PLFDSAAKSLVRRLL 195
P F L+ +L+
Sbjct 286 PYFHPDVVDLLSKLI 300
> tpv:TP02_0378 cAMP-dependent protein kinase; K04345 protein
kinase A [EC:2.7.11.11]
Length=352
Score = 233 bits (593), Expect = 4e-61, Method: Compositional matrix adjust.
Identities = 107/195 (54%), Positives = 143/195 (73%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
+IA KQV+H+ E ++L +SHPFIVNLL S++D+ L+L+MEYV+GG+ F+YLRK +
Sbjct 84 LIAQKQVDHIISENKLLGSVSHPFIVNLLGSYKDDYYLYLVMEYVSGGDFFAYLRKNDRL 143
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
A Y A++T FEYLH+ +I+YRDLKPENLLL + G++K+ DFGFAKVV RT TL
Sbjct 144 KSYDAMFYAAQVTAMFEYLHDNNIIYRDLKPENLLLCSDGYLKLADFGFAKVVEFRTHTL 203
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EY++PE I G+G VD+W LGIL++EML G PPF D+TP +Y KI+ K++FP
Sbjct 204 CGTPEYMSPEIILHLGYGKAVDFWTLGILIYEMLVGYPPFYDETPYNLYDKILKCKLKFP 263
Query 181 PLFDSAAKSLVRRLL 195
+D AK L RLL
Sbjct 264 SFYDEDAKYLTSRLL 278
> bbo:BBOV_III005740 17.m07511; protein kinase domain containing
protein; K04345 protein kinase A [EC:2.7.11.11]
Length=359
Score = 232 bits (591), Expect = 8e-61, Method: Compositional matrix adjust.
Identities = 104/195 (53%), Positives = 145/195 (74%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
+I KQV+HV E+++L+ ++HPFIVN+L +F+D L+++ME V GG+ F YLR +
Sbjct 88 LIVQKQVDHVVSEKKLLSSVNHPFIVNMLGTFKDPHYLYIVMECVFGGDFFGYLRSVDKL 147
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
E A Y A+IT F+Y+H +I+YRDLKPENLL+ + G++K+TDFGFAKVV RT+TL
Sbjct 148 ESESAMFYAAQITCIFDYMHSHNIIYRDLKPENLLVGSDGYLKLTDFGFAKVVELRTYTL 207
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EYLAPE + +GHG VDWW LGIL++EML G PPF ++ P+GIYKKI+ ++ FP
Sbjct 208 CGTPEYLAPEILLNKGHGKAVDWWTLGILIYEMLVGYPPFYNEDPMGIYKKILDCRLVFP 267
Query 181 PLFDSAAKSLVRRLL 195
+D AK+L ++LL
Sbjct 268 RNYDPDAKALTKQLL 282
> sce:YKL166C TPK3; Tpk3p (EC:2.7.11.11); K04345 protein kinase
A [EC:2.7.11.11]
Length=398
Score = 228 bits (581), Expect = 9e-60, Method: Compositional matrix adjust.
Identities = 97/195 (49%), Positives = 141/195 (72%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
++ +KQVEH DERR+L+ +SHPFI+ + +FQD +++F++M+Y+ GGELFS LRK
Sbjct 124 IVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRF 183
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
A+ Y AE+ LA EYLH + I+YRDLKPEN+LLD GHIKITDFGFAK V T+TL
Sbjct 184 PNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTL 243
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT +Y+APE ++ + + VDWW+ G+L++EMLAG PF + + Y+ I+ +++FP
Sbjct 244 CGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFP 303
Query 181 PLFDSAAKSLVRRLL 195
P F A+ L+++L+
Sbjct 304 PFFHPDAQDLLKKLI 318
> sce:YJL164C TPK1, PKA1, SRA3; Tpk1p (EC:2.7.11.11); K04345 protein
kinase A [EC:2.7.11.11]
Length=397
Score = 228 bits (580), Expect = 1e-59, Method: Compositional matrix adjust.
Identities = 99/195 (50%), Positives = 139/195 (71%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
V+ +KQVEH DER +L+ ++HPFI+ + +FQD +++F++M+Y+ GGELFS LRK
Sbjct 123 VVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRF 182
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
A+ Y AE+ LA EYLH + I+YRDLKPEN+LLD GHIKITDFGFAK V T+TL
Sbjct 183 PNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTL 242
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT +Y+APE ++ + + +DWW+ GIL++EMLAG PF D + Y+KI+ ++ FP
Sbjct 243 CGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFP 302
Query 181 PLFDSAAKSLVRRLL 195
P F+ K L+ RL+
Sbjct 303 PFFNEDVKDLLSRLI 317
> hsa:5568 PRKACG, KAPG, PKACg; protein kinase, cAMP-dependent,
catalytic, gamma (EC:2.7.11.11); K04345 protein kinase A [EC:2.7.11.11]
Length=351
Score = 226 bits (577), Expect = 3e-59, Method: Compositional matrix adjust.
Identities = 105/195 (53%), Positives = 140/195 (71%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
V+ MKQVEH+ +E+RIL + PF+V L SF+D L+L+MEYV GGE+FS L++
Sbjct 80 VVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRF 139
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
S A Y A++ LA +YLH +++RDLKPENLL+D QG++++TDFGFAK V GRTWTL
Sbjct 140 SEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTL 199
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EYLAPE I +G+ VDWWALG+L++EM G PPF D P+ IY+KI++G++ FP
Sbjct 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFP 259
Query 181 PLFDSAAKSLVRRLL 195
S K L+R LL
Sbjct 260 SKLSSDLKHLLRSLL 274
> pfa:PFI1685w PfPKAc, PfPKA, PKA; cAMP-dependent protein kinase
catalytic subunit; K04345 protein kinase A [EC:2.7.11.11]
Length=342
Score = 221 bits (564), Expect = 1e-57, Method: Compositional matrix adjust.
Identities = 104/195 (53%), Positives = 136/195 (69%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
+I KQV+HV ER+IL ++HPF VNL SF+D+ L+L++E+V GGE F++LR+
Sbjct 71 IIRQKQVDHVFSERKILNYINHPFCVNLHGSFKDDSYLYLVLEFVIGGEFFTFLRRNKRF 130
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
+ Y A+I L FEYL +IVYRDLKPENLLLD G IK+TDFGFAK+V RT+TL
Sbjct 131 PNDVGCFYAAQIVLIFEYLQSLNIVYRDLKPENLLLDKDGFIKMTDFGFAKIVETRTYTL 190
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGT EY+APE + GHG DWW LGI ++E+L G PPF + PL IY+KI+ G I FP
Sbjct 191 CGTPEYIAPEILLNVGHGKAADWWTLGIFIYEILVGCPPFYANEPLLIYQKILEGIIYFP 250
Query 181 PLFDSAAKSLVRRLL 195
D+ K L+++LL
Sbjct 251 KFLDNNCKHLMKKLL 265
> bbo:BBOV_I004190 19.m02221; cAMP-dependent protein kinase (EC:2.7.11.1);
K04345 protein kinase A [EC:2.7.11.11]
Length=416
Score = 219 bits (558), Expect = 5e-57, Method: Compositional matrix adjust.
Identities = 101/195 (51%), Positives = 137/195 (70%), Gaps = 0/195 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
VIA +QV H+++ER IL+ + HPFIVN + SFQD+ +++L+EYV+GGELFSY+ K ++
Sbjct 144 VIAERQVMHLRNERHILSTVRHPFIVNYVKSFQDDINVYILLEYVSGGELFSYIYKYGAL 203
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
AR Y A+ LA ++LH + IVYRDLKPEN+LLD GHI++ DFGFAK V +T+T+
Sbjct 204 GHTVARFYTAQAILAIDFLHFKGIVYRDLKPENMLLDQDGHIRLVDFGFAKEVKHKTYTV 263
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFP 180
CGTH+YLAPE R GHG++ DWW+LG+L++E+L G PPF P Y +A I FP
Sbjct 264 CGTHDYLAPEIFLRCGHGIEADWWSLGVLVYEILTGVPPFHASDPSATYDLALANHIRFP 323
Query 181 PLFDSAAKSLVRRLL 195
K +RRLL
Sbjct 324 LSVRVEVKDFIRRLL 338
> tpv:TP02_0727 cAMP-dependent protein kinase catalytic subunit;
K04345 protein kinase A [EC:2.7.11.11]
Length=511
Score = 200 bits (508), Expect = 3e-51, Method: Compositional matrix adjust.
Identities = 87/196 (44%), Positives = 136/196 (69%), Gaps = 1/196 (0%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
+I +Q+EHVK+E+ IL+ L HPFIV L SFQD L+ ++E+V GGELF+YLR+ +
Sbjct 240 IIEKRQLEHVKNEKNILSTLKHPFIVGYLGSFQDTLNLYFILEFVPGGELFTYLRRMHTF 299
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAK-VVTGRTWT 119
E R Y +++ LA +YLH +VYRDLKPEN+LLD G+I++ DFGFAK + +G+T+T
Sbjct 300 PPEYTRFYASQVLLALDYLHMNKLVYRDLKPENILLDIMGYIRLVDFGFAKRLESGKTYT 359
Query 120 LCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEF 179
+CGT +YLAPE ++GH + D+++ G+ L+E+L G PPF ++P YK + ++ F
Sbjct 360 VCGTCDYLAPEIFLKKGHDFRADFYSFGVFLYELLTGVPPFYSNSPQKTYKLALNNEVAF 419
Query 180 PPLFDSAAKSLVRRLL 195
++ ++ +++ LL
Sbjct 420 GRKVNNVSRDIIKNLL 435
> pfa:PFL2250c PKB; rac-beta serine/threonine protein kinase,
PfPKB (EC:2.7.1.-); K08286 protein-serine/threonine kinase [EC:2.7.11.-]
Length=735
Score = 197 bits (500), Expect = 3e-50, Method: Composition-based stats.
Identities = 94/198 (47%), Positives = 131/198 (66%), Gaps = 3/198 (1%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
+++ Q+EH K ER IL +SHPFIV + +FQ +++L+ ++EY GGELF +L K
Sbjct 439 ILSRNQLEHTKVERNILKCVSHPFIVKMYYAFQTKQKLYFILEYCPGGELFFHLSKLREF 498
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAK---VVTGRT 117
S E A+ Y +EI LA EYLH+ +I+YRDLKPEN+LLD GHI++TDFG +K T T
Sbjct 499 SEETAKFYSSEIILALEYLHDLNIIYRDLKPENVLLDELGHIRLTDFGLSKEGITETNLT 558
Query 118 WTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKI 177
+LCGT EYLAPE I ++GHG VDWW+LGI+L+EML G PF + +++ I K+
Sbjct 559 KSLCGTPEYLAPEIIEQKGHGKAVDWWSLGIMLYEMLTGELPFNNTNRNVLFESIKYQKL 618
Query 178 EFPPLFDSAAKSLVRRLL 195
+P A L+ +L
Sbjct 619 NYPKNLSPKAVDLLTKLF 636
> pfa:PF14_0346 PKG; cGMP-dependent protein kinase (EC:2.7.11.12);
K07376 protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=853
Score = 192 bits (488), Expect = 6e-49, Method: Compositional matrix adjust.
Identities = 96/198 (48%), Positives = 133/198 (67%), Gaps = 3/198 (1%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
+I + Q ++K ER I A+ HPFI+ L+ +F+D K + L E V GGEL+ +RK +
Sbjct 577 IINLNQQNNIKLEREITAENDHPFIIRLVRTFKDSKYFYFLTELVTGGELYDAIRKLGLL 636
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
S QA+ Y I LA EYLHER+IVYRDLKPEN+LLD QG++K+ DFG AK V GR +TL
Sbjct 637 SKSQAQFYLGSIILAIEYLHERNIVYRDLKPENILLDKQGYVKLIDFGCAKKVQGRAYTL 696
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDD--TPLGIYKKIIAGKIE 178
GT Y+APE I +G+G VD WALGI L+E + G PF +D L I++ I+ G++
Sbjct 697 VGTPHYMAPEVILGKGYGCTVDIWALGICLYEFICGPLPFGNDEEDQLEIFRDILTGQLT 756
Query 179 FPP-LFDSAAKSLVRRLL 195
FP + D+ + +L++RLL
Sbjct 757 FPDYVTDTDSINLMKRLL 774
> bbo:BBOV_I004690 19.m02237; cGMP dependent protein kinase (EC:2.7.11.1);
K07376 protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=887
Score = 192 bits (487), Expect = 8e-49, Method: Compositional matrix adjust.
Identities = 94/196 (47%), Positives = 131/196 (66%), Gaps = 3/196 (1%)
Query 3 AMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISVSV 62
A+KQ +H+K ER I+AQ HPFI+ L+ +F+DE ++ L E + GGEL+ +RK +S
Sbjct 615 ALKQQKHIKLEREIMAQNDHPFIIQLVKTFKDESNVYFLTELITGGELYDAIRKIGLLSR 674
Query 63 EQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTLCG 122
QA+ Y A I LAFEYLHER I YRDLKPEN+LLD QG+IK+ DFG AK + GR +TL G
Sbjct 675 PQAQFYIASIVLAFEYLHERQIAYRDLKPENILLDEQGYIKLIDFGCAKKIKGRAYTLIG 734
Query 123 THEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDT--PLGIYKKIIAGKIEFP 180
T Y+APE I +G+G D W+ G+ L+E + G PF +D + I++ I+ G + FP
Sbjct 735 TPHYMAPEIILGKGYGCLADIWSFGVCLYEFICGPLPFGNDARDQIEIFRDILKGNLVFP 794
Query 181 PLF-DSAAKSLVRRLL 195
D A ++++RLL
Sbjct 795 EYVKDQEAINIIKRLL 810
> cel:T01H8.1 rskn-1; RSK-pNinety (RSK-p90 kinase) homolog family
member (rskn-1); K04373 p90 ribosomal S6 kinase [EC:2.7.11.1]
Length=804
Score = 190 bits (483), Expect = 2e-48, Method: Compositional matrix adjust.
Identities = 90/198 (45%), Positives = 129/198 (65%), Gaps = 3/198 (1%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
+ ++ + K ER ILA +SHPFIV L +FQ E +L+L+++++ GG+LF+ L K++
Sbjct 136 TLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMF 195
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTG---RT 117
+ + + Y AE+TLA E+LH IVYRDLKPEN+LLDA GHIK+TDFG +K +T
Sbjct 196 TEDDVKFYLAELTLALEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKT 255
Query 118 WTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKI 177
++ CGT EY+APE I RRGH + D+W+LG+L+FEML G PF +I+ K+
Sbjct 256 YSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKL 315
Query 178 EFPPLFDSAAKSLVRRLL 195
P A+SL+R L
Sbjct 316 SMPHFLTQEAQSLLRALF 333
Score = 107 bits (267), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 72/210 (34%), Positives = 111/210 (52%), Gaps = 16/210 (7%)
Query 2 IAMKQVEHVKDERRILAQLSH-PFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
I K V +E IL + SH F+V L ++DE ++++ E GGEL L + S+
Sbjct 478 IVKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSL 537
Query 61 SVE-QARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQ----GHIKITDFGFAK---V 112
E + A + A +YLH + + +RDL N+L + ++I DFGFAK
Sbjct 538 GSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRA 597
Query 113 VTGRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFV---DDTPLGIY 169
G T C T +++APE + ++G+ D W+LG+LL ML G PF +DTP I
Sbjct 598 ENGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQIL 657
Query 170 KKIIAGKIEFP-PLFDS---AAKSLVRRLL 195
+++ GKI P++D+ AK LVR++L
Sbjct 658 QRVGDGKISMTHPVWDTISDEAKDLVRKML 687
> tgo:TGME49_111360 cGMP-dependent protein kinase, putative (EC:2.7.11.12);
K07376 protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=994
Score = 190 bits (483), Expect = 2e-48, Method: Compositional matrix adjust.
Identities = 95/198 (47%), Positives = 136/198 (68%), Gaps = 3/198 (1%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
VIA+ Q +H++ ER I+A+ HPFI+ L+ +F+D++ L+ L E V GGEL+ +RK +
Sbjct 720 VIALSQQQHIRLEREIMAENDHPFIIRLVRTFRDKEFLYFLTELVTGGELYDAIRKLGLL 779
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
+ QA+ Y A I LA EYLHER+I YRDLKPEN+LLD+QG++K+ DFG AK + GR +TL
Sbjct 780 ARSQAQFYLASIVLAIEYLHERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTL 839
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTP--LGIYKKIIAGKIE 178
GT Y+APE I +G+ L D WA G+ L+E + G PF +D L I++ I+ GK+
Sbjct 840 VGTPHYMAPEVILGKGYTLTADTWAFGVCLYEFMCGPLPFGNDAEDQLEIFRDILTGKLV 899
Query 179 FPP-LFDSAAKSLVRRLL 195
FP + D A +L++RLL
Sbjct 900 FPHYVTDQDAINLMKRLL 917
> tgo:TGME49_067540 protein kinase, putative (EC:4.1.1.70 2.7.11.13)
Length=951
Score = 190 bits (482), Expect = 3e-48, Method: Composition-based stats.
Identities = 90/200 (45%), Positives = 130/200 (65%), Gaps = 7/200 (3%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
V+ QVEH + ER +LA +SHPFIV + +FQ K+L+ ++EY GGELF +L +
Sbjct 495 VVRRNQVEHTRTERDVLAWVSHPFIVQMHYAFQTRKKLYFVLEYCPGGELFFHLSRAGRF 554
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKV-----VTG 115
A Y AE+ LA E+LH+ ++VYRDLKPEN+LLD GH+++TDFG +K +
Sbjct 555 KEYAACFYAAEVLLALEHLHKYNVVYRDLKPENVLLDEHGHVRLTDFGLSKEGVEDNCSA 614
Query 116 RTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG 175
R +LCGT EYLAPE ++++GHG VDWW+LG L++EML G PPF +++ I +
Sbjct 615 R--SLCGTPEYLAPEILSQQGHGKAVDWWSLGALIYEMLTGLPPFYTGDRERLFENIRSS 672
Query 176 KIEFPPLFDSAAKSLVRRLL 195
++++P AA L+R L
Sbjct 673 ELQYPSYMSRAAVHLLRGLF 692
> dre:100125912 prkg2; protein kinase, cGMP-dependent, type II
(EC:2.7.11.1); K07376 protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=768
Score = 189 bits (479), Expect = 6e-48, Method: Compositional matrix adjust.
Identities = 91/198 (45%), Positives = 129/198 (65%), Gaps = 4/198 (2%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
++ +Q EH+ ERRIL + + PFIV + +++D K +++L+E GGE++S LR + S
Sbjct 495 IVDNRQEEHIYSERRILLETNCPFIVKMYRTYKDNKYVYMLLEACLGGEIWSLLRDRGSF 554
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVT--GRTW 118
A+ +T AF+YLH I+YRDLKPENL+LD G++K+ DFGFAK + RTW
Sbjct 555 EEYTAKFCVGCVTEAFDYLHNNGIIYRDLKPENLMLDTDGYVKLVDFGFAKKLKCGQRTW 614
Query 119 TLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG--K 176
T CGT EY+APE I +GHGL VD+W+LGIL+FE+L G PPF + IY I+ G K
Sbjct 615 TFCGTPEYVAPEIILNKGHGLSVDFWSLGILIFELLTGSPPFTGSDQMIIYTFILKGIEK 674
Query 177 IEFPPLFDSAAKSLVRRL 194
++FP L+R+L
Sbjct 675 MDFPKKITKRPGDLIRKL 692
> cel:R04A9.7 hypothetical protein; K04688 p70 ribosomal S6 kinase
[EC:2.7.11.1]
Length=402
Score = 189 bits (479), Expect = 6e-48, Method: Compositional matrix adjust.
Identities = 86/194 (44%), Positives = 129/194 (66%), Gaps = 3/194 (1%)
Query 5 KQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISVSVEQ 64
K + H +DER+IL ++ PF+ +L +FQ ++L+L++E+++GGEL++ L ++ E
Sbjct 93 KDLRHARDERKILETINSPFLCDLHYAFQTNEKLYLVLEFLHGGELYTLLERKSDWPEEY 152
Query 65 ARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTG---RTWTLC 121
AR Y +EI LA E+LH IVYRDLKP+N++L+ GH+ +TDFG K +T T C
Sbjct 153 ARFYLSEIILAIEHLHGHDIVYRDLKPDNVMLNLAGHVVLTDFGLCKYKLKKGEKTLTFC 212
Query 122 GTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFPP 181
GTHEY+APE I + GH VD WALGIL+++M G PPF +TP K I+ GK+ PP
Sbjct 213 GTHEYMAPEMIRKVGHDHAVDVWALGILMYDMFMGGPPFTGETPADKDKSILKGKVRLPP 272
Query 182 LFDSAAKSLVRRLL 195
++ K L++R++
Sbjct 273 KLSASGKDLIKRII 286
> hsa:5593 PRKG2, PRKGR2, cGKII; protein kinase, cGMP-dependent,
type II (EC:2.7.11.12); K07376 protein kinase, cGMP-dependent
[EC:2.7.11.12]
Length=762
Score = 188 bits (478), Expect = 8e-48, Method: Compositional matrix adjust.
Identities = 93/198 (46%), Positives = 130/198 (65%), Gaps = 4/198 (2%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
++ KQ EHV E+RIL +L PFIV L +F+D K +++L+E GGEL+S LR + S
Sbjct 489 IVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSF 548
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTG--RTW 118
++ A +T AF+YLH I+YRDLKPENL+LDA+G++K+ DFGFAK + +TW
Sbjct 549 DEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTW 608
Query 119 TLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG--K 176
T CGT EY+APE I +GH VD+W+LGIL++E+L G PPF + Y I+ G K
Sbjct 609 TFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEK 668
Query 177 IEFPPLFDSAAKSLVRRL 194
++FP + L+RRL
Sbjct 669 MDFPRKITRRPEDLIRRL 686
> cel:Y47D3A.16 rsks-1; RSK-pSeventy (RSK-p70 kinase) homolog
family member (rsks-1); K04688 p70 ribosomal S6 kinase [EC:2.7.11.1]
Length=580
Score = 188 bits (478), Expect = 9e-48, Method: Compositional matrix adjust.
Identities = 90/198 (45%), Positives = 129/198 (65%), Gaps = 3/198 (1%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
V K H K ER IL + PFI +LL +FQ +L+L++EY++GGELF +L ++
Sbjct 123 VRNQKDTAHTKAERNILEAVKSPFICDLLYAFQTGGKLYLILEYLSGGELFMHLEREGMF 182
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAK-VVTG--RT 117
A+ Y +EI ++ E+LH++ I+YRDLKPEN+LLDA GH+K+TDFG K + G +T
Sbjct 183 MENVAKFYLSEIVVSLEHLHQQGIIYRDLKPENILLDAYGHVKLTDFGLCKEEIEGDQKT 242
Query 118 WTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKI 177
T CGT EY+APE + R GHG VDWW+LG L+F+ML G PPF + KI+ G++
Sbjct 243 HTFCGTIEYMAPEILMRCGHGKAVDWWSLGALMFDMLTGGPPFTAENRRKTIDKILKGRL 302
Query 178 EFPPLFDSAAKSLVRRLL 195
P + A+ L+++LL
Sbjct 303 TLPAYLSNEARDLIKKLL 320
> dre:406349 rps6kb1b, fc51h01, rps6kb1, wu:fc51h01, zgc:55713;
ribosomal protein S6 kinase b, polypeptide 1b (EC:2.7.11.1);
K04688 p70 ribosomal S6 kinase [EC:2.7.11.1]
Length=502
Score = 188 bits (477), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 89/194 (45%), Positives = 127/194 (65%), Gaps = 3/194 (1%)
Query 5 KQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISVSVEQ 64
K H K ER IL ++ HPFIV+L+ +FQ +L+L++EY++GGELF L ++ +
Sbjct 109 KDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDT 168
Query 65 ARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAK--VVTGR-TWTLC 121
A Y AEI++A +LH++ I+YRDLKPEN++L+ QGH+K+TDFG K + G T T C
Sbjct 169 ACFYLAEISMALGHLHQKGIIYRDLKPENIMLNNQGHVKLTDFGLCKESIHDGTVTHTFC 228
Query 122 GTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFPP 181
GT EY+APE + R GH VDWW+LG L+++ML G PPF + KI+ K+ PP
Sbjct 229 GTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPP 288
Query 182 LFDSAAKSLVRRLL 195
A+ L++RLL
Sbjct 289 YLTQEARDLLKRLL 302
> mmu:19092 Prkg2, AW212535, CGKII, MGC130517, Prkgr2, cGK-II;
protein kinase, cGMP-dependent, type II (EC:2.7.11.12); K07376
protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=762
Score = 187 bits (476), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 93/198 (46%), Positives = 129/198 (65%), Gaps = 4/198 (2%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
++ KQ EHV E+RIL +L PFIV L +F+D K +++L+E GGEL+S LR + S
Sbjct 489 IVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSF 548
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTG--RTW 118
++ A +T AF+YLH I+YRDLKPENL+LDA G++K+ DFGFAK + +TW
Sbjct 549 DEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDADGYLKLVDFGFAKKIGSGQKTW 608
Query 119 TLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG--K 176
T CGT EY+APE I +GH VD+W+LGIL++E+L G PPF + Y I+ G K
Sbjct 609 TFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGIDQMMTYNLILKGIEK 668
Query 177 IEFPPLFDSAAKSLVRRL 194
++FP + L+RRL
Sbjct 669 MDFPRKITRRPEDLIRRL 686
> cpv:cgd8_750 cyclic nucleotide (cGMP)-dependent protein kinase
with 3 cNMP binding domains and a Ser/Thr kinase domain ;
K07376 protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=965
Score = 187 bits (476), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 96/198 (48%), Positives = 133/198 (67%), Gaps = 3/198 (1%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
++A+ HVK ER ILA HPFI+ L+ +F+D + ++LL E + GGEL+ L++ +
Sbjct 658 ILALNMQAHVKLERSILALNDHPFIIKLVRTFKDSENIYLLTELIPGGELYDALQRIGLL 717
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGRTWTL 120
+ QA+ Y I LA EYLHERSIVYRDLKPEN+LLD+QG+IK+ DFG AK + GR++TL
Sbjct 718 TRYQAQFYIGSIILALEYLHERSIVYRDLKPENILLDSQGYIKLIDFGCAKKIAGRSYTL 777
Query 121 CGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDT--PLGIYKKIIAGKIE 178
GT Y+APE I +G+ L D WA+GI L+E L G PF +D L I+K I+ K+
Sbjct 778 AGTPHYMAPEVILGKGYNLSCDAWAIGICLYEFLCGCLPFGNDAVDHLEIFKDILTSKLV 837
Query 179 FPP-LFDSAAKSLVRRLL 195
FP L D ++++RLL
Sbjct 838 FPRHLNDVDTVNIIKRLL 855
> dre:562242 ribosomal protein S6 kinase b, polypeptide 1-like;
K04688 p70 ribosomal S6 kinase [EC:2.7.11.1]
Length=507
Score = 187 bits (474), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 89/194 (45%), Positives = 128/194 (65%), Gaps = 3/194 (1%)
Query 5 KQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISVSVEQ 64
K H K ER IL ++ HPFIV+L+ +FQ ++L+L++EY++GGELF L ++ +
Sbjct 110 KDTAHTKAERSILEEVKHPFIVDLIYAFQTGEKLYLILEYLSGGELFMQLEREGIFLEDT 169
Query 65 ARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAK--VVTGR-TWTLC 121
A Y AEI+LA +LH++ I+YRDLKPEN++L+ GH+K+TDFG K + G T T C
Sbjct 170 ACFYLAEISLALGHLHQKGIIYRDLKPENIMLNYNGHVKLTDFGLCKESIHDGTVTHTFC 229
Query 122 GTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFPP 181
GT EY+APE +TR GH VDWW+LG L+++ML G PPF + KI+ K+ PP
Sbjct 230 GTIEYMAPEILTRSGHNRAVDWWSLGALMYDMLTGAPPFTAENRKKTIDKILKCKLNLPP 289
Query 182 LFDSAAKSLVRRLL 195
A+ L+++LL
Sbjct 290 YLTQEARDLLKKLL 303
> xla:394276 rps6kb1, p70-alpha, p70-s6k, p70s6k, ps6k, rps6kb1-A,
s6K1, s6k, stk14a; ribosomal protein S6 kinase, 70kDa,
polypeptide 1 (EC:2.7.11.1); K04688 p70 ribosomal S6 kinase
[EC:2.7.11.1]
Length=501
Score = 186 bits (471), Expect = 6e-47, Method: Compositional matrix adjust.
Identities = 88/194 (45%), Positives = 127/194 (65%), Gaps = 3/194 (1%)
Query 5 KQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISVSVEQ 64
K H K ER IL ++ HPFIV+L+ +FQ +L+L++EY++GGELF L ++ +
Sbjct 111 KDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDT 170
Query 65 ARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAK--VVTGR-TWTLC 121
A Y AEI++A +LH++ I+YRDLKPEN++L+ QGH+K+TDFG K + G T T C
Sbjct 171 ACFYLAEISMALGHLHQKGIIYRDLKPENIMLNLQGHVKLTDFGLCKESIHDGTVTHTFC 230
Query 122 GTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFPP 181
GT EY+APE + R GH VDWW+LG L+++ML G PPF + KI+ K+ PP
Sbjct 231 GTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFSGENRKKTIDKILKCKLNLPP 290
Query 182 LFDSAAKSLVRRLL 195
A+ L+++LL
Sbjct 291 YLTQEARDLLKKLL 304
> mmu:72508 Rps6kb1, 2610318I15Rik, 4732464A07Rik, 70kDa, AA959758,
AI256796, AI314060, S6K1, p70/85s6k, p70s6k; ribosomal
protein S6 kinase, polypeptide 1 (EC:2.7.11.1); K04688 p70
ribosomal S6 kinase [EC:2.7.11.1]
Length=525
Score = 185 bits (470), Expect = 7e-47, Method: Compositional matrix adjust.
Identities = 88/194 (45%), Positives = 127/194 (65%), Gaps = 3/194 (1%)
Query 5 KQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISVSVEQ 64
K H K ER IL ++ HPFIV+L+ +FQ +L+L++EY++GGELF L ++ +
Sbjct 135 KDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDT 194
Query 65 ARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAK--VVTGR-TWTLC 121
A Y AEI++A +LH++ I+YRDLKPEN++L+ QGH+K+TDFG K + G T T C
Sbjct 195 ACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFC 254
Query 122 GTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFPP 181
GT EY+APE + R GH VDWW+LG L+++ML G PPF + KI+ K+ PP
Sbjct 255 GTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPP 314
Query 182 LFDSAAKSLVRRLL 195
A+ L+++LL
Sbjct 315 YLTQEARDLLKKLL 328
> hsa:6198 RPS6KB1, PS6K, S6K, S6K1, STK14A, p70(S6K)-alpha, p70-S6K,
p70-alpha; ribosomal protein S6 kinase, 70kDa, polypeptide
1 (EC:2.7.11.1); K04688 p70 ribosomal S6 kinase [EC:2.7.11.1]
Length=525
Score = 185 bits (470), Expect = 7e-47, Method: Compositional matrix adjust.
Identities = 88/194 (45%), Positives = 127/194 (65%), Gaps = 3/194 (1%)
Query 5 KQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISVSVEQ 64
K H K ER IL ++ HPFIV+L+ +FQ +L+L++EY++GGELF L ++ +
Sbjct 135 KDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDT 194
Query 65 ARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAK--VVTGR-TWTLC 121
A Y AEI++A +LH++ I+YRDLKPEN++L+ QGH+K+TDFG K + G T T C
Sbjct 195 ACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFC 254
Query 122 GTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIEFPP 181
GT EY+APE + R GH VDWW+LG L+++ML G PPF + KI+ K+ PP
Sbjct 255 GTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPP 314
Query 182 LFDSAAKSLVRRLL 195
A+ L+++LL
Sbjct 315 YLTQEARDLLKKLL 328
> hsa:6199 RPS6KB2, KLS, P70-beta, P70-beta-1, P70-beta-2, S6K-beta2,
S6K2, SRK, STK14B, p70(S6K)-beta, p70S6Kb; ribosomal
protein S6 kinase, 70kDa, polypeptide 2 (EC:2.7.11.1); K04688
p70 ribosomal S6 kinase [EC:2.7.11.1]
Length=482
Score = 185 bits (470), Expect = 7e-47, Method: Compositional matrix adjust.
Identities = 91/198 (45%), Positives = 123/198 (62%), Gaps = 3/198 (1%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
V K H + ER IL + HPFIV L +FQ +L+L++E ++GGELF++L ++
Sbjct 107 VRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIF 166
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGR---T 117
+ A Y AEITLA +LH + I+YRDLKPEN++L +QGHIK+TDFG K T
Sbjct 167 LEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVT 226
Query 118 WTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKI 177
T CGT EY+APE + R GH VDWW+LG L+++ML G PPF + KII GK+
Sbjct 227 HTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKL 286
Query 178 EFPPLFDSAAKSLVRRLL 195
PP A+ LV++ L
Sbjct 287 ALPPYLTPDARDLVKKFL 304
> mmu:58988 Rps6kb2, 70kDa, S6K2; ribosomal protein S6 kinase,
polypeptide 2 (EC:2.7.11.1); K04688 p70 ribosomal S6 kinase
[EC:2.7.11.1]
Length=485
Score = 185 bits (470), Expect = 7e-47, Method: Compositional matrix adjust.
Identities = 90/198 (45%), Positives = 122/198 (61%), Gaps = 3/198 (1%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
V + K H + ER IL + HPFIV L +FQ +L+L++E ++GGELF++L ++
Sbjct 107 VCSAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIF 166
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVVTGR---T 117
+ A Y AEITLA +LH I+YRDLKPEN++L +QGHIK+TDFG K T
Sbjct 167 LEDTACFYLAEITLALGHLHSHGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAIT 226
Query 118 WTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKI 177
T CGT EY+APE + R GH VDWW+LG L+++ML G PPF + KII GK+
Sbjct 227 HTFCGTIEYMAPEILVRTGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKL 286
Query 178 EFPPLFDSAAKSLVRRLL 195
PP A+ L ++ L
Sbjct 287 VLPPYLTPDARDLAKKFL 304
> dre:566430 cGMP dependent protein kinase I
Length=528
Score = 185 bits (469), Expect = 1e-46, Method: Compositional matrix adjust.
Identities = 88/198 (44%), Positives = 127/198 (64%), Gaps = 4/198 (2%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
++ +Q EH++ E++I+ + FIV L +F+D K L++LME GGEL++ LR + S
Sbjct 254 IVDTRQQEHIRSEKQIMQEAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSF 313
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVV--TGRTW 118
R Y A + AF YLH + I+YRDLKPENL+LD +G+ K+ DFGFAK + +TW
Sbjct 314 EDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTW 373
Query 119 TLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG--K 176
T CGT EY+APE I +GH + D+W+LGIL++E+L G PPF P+ Y I+ G
Sbjct 374 TFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDM 433
Query 177 IEFPPLFDSAAKSLVRRL 194
IEFP A +L+++L
Sbjct 434 IEFPKKITKNAGNLIKKL 451
> mmu:19091 Prkg1, AW125416, CGKI, MGC132849, Prkg1b, Prkgr1b;
protein kinase, cGMP-dependent, type I (EC:2.7.11.12); K07376
protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=671
Score = 183 bits (465), Expect = 3e-46, Method: Compositional matrix adjust.
Identities = 88/198 (44%), Positives = 126/198 (63%), Gaps = 4/198 (2%)
Query 1 VIAMKQVEHVKDERRILAQLSHPFIVNLLASFQDEKRLFLLMEYVNGGELFSYLRKQISV 60
++ +Q EH++ E++I+ FIV L +F+D K L++LME GGEL++ LR + S
Sbjct 397 IVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSF 456
Query 61 SVEQARLYCAEITLAFEYLHERSIVYRDLKPENLLLDAQGHIKITDFGFAKVV--TGRTW 118
R Y A + AF YLH + I+YRDLKPENL+LD +G+ K+ DFGFAK + +TW
Sbjct 457 EDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTW 516
Query 119 TLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG--K 176
T CGT EY+APE I +GH + D+W+LGIL++E+L G PPF P+ Y I+ G
Sbjct 517 TFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDM 576
Query 177 IEFPPLFDSAAKSLVRRL 194
IEFP A +L+++L
Sbjct 577 IEFPKKIAKNAANLIKKL 594
Lambda K H
0.326 0.142 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 5673387808
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
Posted date: Sep 17, 2011 2:57 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40