bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
164,496 sequences; 82,071,388 total letters
Query= Eten_1291_orf3
Length=453
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_057010 insulysin, putative (EC:3.4.24.56); K01408 i... 624 3e-178
cpv:cgd1_1680 insulinase like protease, signal peptide ; K0140... 265 3e-70
cpv:cgd2_930 peptidase'insulinase-like peptidase' ; K01408 ins... 222 2e-57
dre:561390 ide, MGC162603, zgc:162603; insulin-degrading enzym... 222 3e-57
sce:YLR389C STE23; Metalloprotease involved, with homolog Axl1... 216 1e-55
mmu:15925 Ide, 1300012G03Rik, 4833415K22Rik, AA675336, AI50753... 216 2e-55
dre:557565 nrd1, si:dkey-171o17.4; nardilysin (N-arginine diba... 214 5e-55
ath:AT2G41790 peptidase M16 family protein / insulinase family... 211 4e-54
cel:C02G6.2 hypothetical protein; K01408 insulysin [EC:3.4.24.56] 204 4e-52
dre:565850 fk24c07; wu:fk24c07; K01411 nardilysin [EC:3.4.24.61] 203 9e-52
mmu:230598 Nrd1, 2600011I06Rik, AI875733, MGC25477, NRD-C; nar... 200 7e-51
ath:AT1G06900 catalytic/ metal ion binding / metalloendopeptid... 200 8e-51
hsa:4898 NRD1, hNRD1, hNRD2; nardilysin (N-arginine dibasic co... 199 1e-50
tgo:TGME49_069890 M16 family peptidase, putative (EC:3.4.24.56) 196 1e-49
cel:Y70C5C.1 hypothetical protein; K01408 insulysin [EC:3.4.24... 192 3e-48
cel:C28F5.4 hypothetical protein; K01408 insulysin [EC:3.4.24.56] 188 5e-47
cel:F44E7.4 hypothetical protein; K01408 insulysin [EC:3.4.24.56] 187 8e-47
cpv:cgd2_920 peptidase'insulinase-like peptidase' 185 3e-46
eco:b2821 ptrA, ECK2817, JW2789, ptr; protease III (EC:3.4.24.... 180 9e-45
cel:C02G6.1 hypothetical protein; K01408 insulysin [EC:3.4.24.56] 180 1e-44
ath:AT3G57470 peptidase M16 family protein / insulinase family... 165 4e-40
cpv:cgd3_4260 peptidase'insulinase like peptidase' ; K01408 in... 164 5e-40
cpv:cgd3_4270 peptidase'insulinase like peptidase' ; K01408 in... 152 3e-36
tgo:TGME49_044480 insulin-degrading enzyme, putative (EC:3.4.2... 141 4e-33
cpv:cgd2_4270 secreted insulinase-like peptidase 132 3e-30
sce:YPR122W AXL1, FUS5, STE22; Axl1p (EC:3.4.24.-); K01422 [E... 129 2e-29
cpv:cgd3_4240 insulinase like peptidase ; K01408 insulysin [EC... 118 5e-26
cpv:cgd6_5520 peptidase'insulinase like peptidase' ; K01408 in... 117 1e-25
cpv:cgd3_4170 secreted insulinase like peptidase 107 1e-22
tgo:TGME49_006510 peptidase M16 domain containing protein (EC:... 91.7 6e-18
cpv:cgd3_4180 secreted insulinase like peptidase 77.8 9e-14
cpv:cgd3_4210 secreted insulinase like peptidase, signal peptide 72.8 3e-12
eco:b1494 pqqL, ECK1488, JW1489, pqqE, pqqM, yddC; predicted p... 71.2 8e-12
cpv:cgd3_4280 secreted insulinase like peptidase, signal peptide 68.2 7e-11
ath:AT3G02090 MPPBETA; mitochondrial processing peptidase beta... 67.4 1e-10
pfa:PF11_0226 petidase, M16 family 66.2 2e-10
ath:AT5G42390 metalloendopeptidase 58.5 5e-08
sce:YLR163C MAS1, MIF1; Mas1p (EC:3.4.24.64); K01412 mitochond... 57.8 8e-08
tgo:TGME49_036210 mitochondrial-processing peptidase beta subu... 57.4 1e-07
cpv:cgd3_4250 secreted insulinase like peptidase, signal peptide 56.2 2e-07
cpv:cgd3_4200 secreted insulinase like peptidase, signal peptide 55.8 3e-07
tpv:TP01_0151 biquinol-cytochrome C reductase complex core pro... 55.1 6e-07
bbo:BBOV_IV001260 21.m02910; mitochondrial processing peptidas... 54.7 8e-07
pfa:PFI1625c organelle processing peptidase, putative; K01412 ... 53.9 1e-06
dre:503532 pmpcb, zgc:110738; peptidase (mitochondrial process... 52.4 4e-06
dre:393793 uqcrc1, MGC73404, zgc:73404, zgc:85750; ubiquinol-c... 52.0 5e-06
hsa:9512 PMPCB, Beta-MPP, MPP11, MPPB, MPPP52, P-52; peptidase... 51.6 5e-06
mmu:73078 Pmpcb, 3110004O18Rik, MPP11, MPPB, MPPP52; peptidase... 51.6 6e-06
cpv:cgd5_3400 mitochondrial processing peptidase beta subunit ... 51.6 7e-06
ath:AT5G56730 peptidase M16 family protein / insulinase family... 49.7 3e-05
> tgo:TGME49_057010 insulysin, putative (EC:3.4.24.56); K01408
insulysin [EC:3.4.24.56]
Length=953
Score = 624 bits (1608), Expect = 3e-178, Method: Compositional matrix adjust.
Identities = 279/430 (64%), Positives = 352/430 (81%), Gaps = 0/430 (0%)
Query 24 AIGALANDVLKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPG 83
A+G + +VLKP ADYRDF H+QL NGM +A+HHP++ E ++VA NTGSLYDPED+PG
Sbjct 15 AVGCVCGEVLKPGADYRDFHHFQLPNGMQCLAIHHPKTTEGAYSVAVNTGSLYDPEDLPG 74
Query 84 LAHFLEHMLFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRF 143
LAHFLEHMLFLGTSK+PEPESYD F+++ GG NNAYTDEEKTVFFN+V+D E+ALDRF
Sbjct 75 LAHFLEHMLFLGTSKHPEPESYDKFMSERGGQNNAYTDEEKTVFFNQVSDKYLEDALDRF 134
Query 144 SEFFKAPLFDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLAKGPMSRFATGNSATLS 203
S+FFK+PLF+ +YEE+E +A+D+EHQKN+PND+ER W+TIRSLAKGP+SRFATGN TL+
Sbjct 135 SQFFKSPLFNPEYEEREAHAVDSEHQKNVPNDEERTWFTIRSLAKGPLSRFATGNLETLN 194
Query 204 TNPKAKGIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADWLG 263
T PK KGI++V RL+DFH KYYC SNM V +SPRSL EQE+L+R+ E +++G+ ++LG
Sbjct 195 TAPKRKGINVVSRLKDFHKKYYCASNMAVVIMSPRSLVEQETLLRKSFEDVTSGNPNFLG 254
Query 264 MVQCPGPMFDTVKPFDHTNSGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQPTSVLTYLL 323
QCPG +D PFD +N+GKFIHLQS + SLWVAF LPPT+TSYKKQPT +LTYL
Sbjct 255 FDQCPGVDYDRTPPFDLSNTGKFIHLQSVGGESSLWVAFSLPPTITSYKKQPTGILTYLF 314
Query 324 EYTGEGSLAKRLRLLGLADGISPVVDRNTISTLLGLKVDLTQKGATHRGLVLQEIFSYIN 383
EY+G+GSL+KRLR +GLAD +S V DR ++STL +KVDL KGA+ RG VL+E+FSYIN
Sbjct 315 EYSGDGSLSKRLRTMGLADEVSVVADRTSVSTLFAVKVDLASKGASERGAVLEEVFSYIN 374
Query 384 FLRDHGVGHDLVSTLAQQSHVDFHTTQPSSSLMDEAARLAHNLLTYEPYHVVAGDSLLID 443
L++ GV +S++++QS VDFHT+QP M+E ARLAHNLLTYEPYHV+AGDSLL+D
Sbjct 375 LLKNEGVDSKTISSISEQSLVDFHTSQPDPPAMNEVARLAHNLLTYEPYHVLAGDSLLVD 434
Query 444 ADPRLTNQLL 453
D + NQLL
Sbjct 435 PDAQFVNQLL 444
> cpv:cgd1_1680 insulinase like protease, signal peptide ; K01408
insulysin [EC:3.4.24.56]
Length=1033
Score = 265 bits (677), Expect = 3e-70, Method: Compositional matrix adjust.
Identities = 149/436 (34%), Positives = 236/436 (54%), Gaps = 7/436 (1%)
Query 23 SAIGALANDVLKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVP 82
S+I VLKP+ D R +++ L NG+ A+ + S +AGF V GS +P
Sbjct 29 SSIWKSGYSVLKPKTDDRSYKNITLENGITALLIEDKFSEKAGFTVGIKVGSFNNPVYAL 88
Query 83 GLAHFLEHMLFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDR 142
GL H +EH+LFLGT KYP PESYD F+ Q+GG NNAYT EE+T++FN++ + EE LDR
Sbjct 89 GLFHLIEHVLFLGTKKYPAPESYDEFMAQHGGKNNAYTSEERTIYFNEIGEEYLEEGLDR 148
Query 143 FSEFFKAPLFDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLAKGPMSRFATGNSATL 202
FS FF PLF EKE++ I++EH KNIPN+ +R ++ +++ PMS+F TGN TL
Sbjct 149 FSHFFIDPLFYENVIEKEIHIINSEHLKNIPNEFDRLFHMLKTHTNKPMSQFTTGNIETL 208
Query 203 STNPKAKGIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGI---SAGHA 259
P GI + L+ + KYYCG NM V S RSL +QE L+++ G+ + G
Sbjct 209 VDIPNKLGISIPRLLKKMYKKYYCGINMFIVLSSKRSLTDQEKLLQKYFSGVLIDNDGQC 268
Query 260 DWLGMVQCPGPMFDTVKPFDHTNSGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQPTSVL 319
++ + + G + ++ D K IH++S + LW+ + P L S KQP L
Sbjct 269 EFSSLKKEHGILNKSI--IDQKYLSKKIHVKSLGGRDLLWLIWSFPARLISPVKQPLIYL 326
Query 320 TYLLEYTGEGSLAKRLRLLGLADGISPVVDRNTISTLLGLKVDLTQKGATHRGLVLQEIF 379
+Y+L + SL L+ + V + T ++ +++LT +G ++ ++ I+
Sbjct 327 SYILNSKQKNSLFWFLQKNNYITNSNSVYENYTFGSIFIYQLELTSEGLKNQFEIIGLIY 386
Query 380 SYINFLRDHGVGHDLVSTLAQQSHVDF--HTTQPSSSLMDEAARLAHNLLTYEPYHVVAG 437
YIN L++ + + + +F +T SS M + + ++ Y + ++G
Sbjct 387 KYINKLKESKELLKVYQGIRSLTEREFITNTEMLESSPMHSTSEICSKMIQYGVHAALSG 446
Query 438 DSLLIDADPRLTNQLL 453
D L+ D D L ++L
Sbjct 447 DILIEDVDENLIYEIL 462
> cpv:cgd2_930 peptidase'insulinase-like peptidase' ; K01408 insulysin
[EC:3.4.24.56]
Length=1013
Score = 222 bits (565), Expect = 2e-57, Method: Compositional matrix adjust.
Identities = 125/394 (31%), Positives = 211/394 (53%), Gaps = 6/394 (1%)
Query 25 IGALANDVLKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGL 84
+ + N++ KP D +R L N + + V ++ +G +++ G DPE++ GL
Sbjct 8 LKEIQNEITKPIYDDNKYRALVLKNNLRVLLVQDENTDISGASMSVFVGCQQDPEELNGL 67
Query 85 AHFLEHMLFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFS 144
AHFLEHMLFLG++++P P +D ++ NGG++NA+TD T +F ++ + +FE ALD FS
Sbjct 68 AHFLEHMLFLGSARHPNPSDFDDYMKLNGGSSNAFTDNLSTSYFFEIKNESFEHALDLFS 127
Query 145 EFFKAPLFDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLAKG--PMSRFATGNSATL 202
FF PLFD KY ++EVNA+++EH KN+ +D ++ I S+A+ P+ +F TG+ TL
Sbjct 128 AFFICPLFDTKYVDREVNAVNSEHNKNLLSDLWIRYHVISSIARNGHPLRKFGTGSIETL 187
Query 203 STNPKAKGIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGI---SAGHA 259
P+ KGIDL+ L++FH+KYY +NM +S LDE ES + I +
Sbjct 188 KYEPEKKGIDLIAELKNFHNKYYSSNNMFLTLVSNCDLDELESYAIKYFSEIVDKNIARV 247
Query 260 DWLGMVQCPGPMFDTVKPFDHTNSGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQPTSVL 319
D+ G Q P ++ + +++ + + F +P K P
Sbjct 248 DYFGEFQKERPYLSIMESPEDGALESMVYVIPNKDEKKVSFNFQIPDLRKFRKGLPEMYF 307
Query 320 TYLLEYTGEGSLAKRLRLLGLADGISPVVDRNTISTLLGLKVDLTQKGATHRGLVLQEIF 379
T +L + G GSL LR G +S ++ + L + + LT+KGA V++
Sbjct 308 TNILGHEGPGSLTSALRRNGWCLALSSGLNEMYSANLFEIIITLTEKGAREVLSVIEYTL 367
Query 380 SYINFLRDHGVGHDLVSTLAQQSHVDF-HTTQPS 412
+++N + + + ++VS L + S + F + +PS
Sbjct 368 NFVNLVIKNEIDMEVVSDLEKLSQLVFDYRNRPS 401
> dre:561390 ide, MGC162603, zgc:162603; insulin-degrading enzyme
(EC:3.4.24.56); K01408 insulysin [EC:3.4.24.56]
Length=978
Score = 222 bits (565), Expect = 3e-57, Method: Compositional matrix adjust.
Identities = 125/369 (33%), Positives = 199/369 (53%), Gaps = 12/369 (3%)
Query 24 AIGALANDVLKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPG 83
A+ + +D+++ D R++R + +NG+ AI + P ++++ A+ + GSL DPE++ G
Sbjct 5 AVKRVVSDIIRSPEDKREYRGLEFTNGLKAILISDPTTDKSSAALDVHMGSLSDPENISG 64
Query 84 LAHFLEHMLFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRF 143
LAHF EHMLFLGT KYP+ Y FL+++ G++NA+T E T ++ V+ + ALDRF
Sbjct 65 LAHFCEHMLFLGTEKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLQGALDRF 124
Query 144 SEFFKAPLFDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLA--KGPMSRFATGNSAT 201
++FF PLFD +++EVNA+D+EH+KN+ ND R + ++ K P S+F TGN T
Sbjct 125 AQFFLCPLFDESCKDREVNAVDSEHEKNLMNDAWRLFQLEKATGNPKHPFSKFGTGNKLT 184
Query 202 LSTNPKAKGIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADW 261
L T P +GID+ + L FHS YY + M + +LDE S++ + + +
Sbjct 185 LETRPSQQGIDIREELLKFHSTYYSSNLMGLCVLGRETLDELTSMVVKLFGEVENKNV-- 242
Query 262 LGMVQCPGPMFDTVKPFDHTNSGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQPTSVLTY 321
P P F T PF + +F + +L+V F +P YK P L +
Sbjct 243 ------PVPEFPT-HPFQEEHLRQFYKVVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGH 295
Query 322 LLEYTGEGSLAKRLRLLGLADGISPVVDRNTISTLLG-LKVDLTQKGATHRGLVLQEIFS 380
L+ + G GSL L+ G + + + + VDLT++G H ++ +F
Sbjct 296 LIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIIFHMFQ 355
Query 381 YINFLRDHG 389
YI LR G
Sbjct 356 YIQKLRTEG 364
> sce:YLR389C STE23; Metalloprotease involved, with homolog Axl1p,
in N-terminal processing of pro-A-factor to the mature
form; member of the insulin-degrading enzyme family (EC:3.4.24.-);
K01408 insulysin [EC:3.4.24.56]
Length=1027
Score = 216 bits (550), Expect = 1e-55, Method: Compositional matrix adjust.
Identities = 140/433 (32%), Positives = 230/433 (53%), Gaps = 30/433 (6%)
Query 31 DVLKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEH 90
D LKP+ D R +R +L N + A+ + P++++A ++ N G+ DP+++PGLAHF EH
Sbjct 63 DFLKPDLDERSYRFIELPNKLKALLIQDPKADKAAASLDVNIGAFEDPKNLPGLAHFCEH 122
Query 91 MLFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAP 150
+LF+G+ K+P+ Y S+L+++GG++NAYT + T +F +V ALDRFS FF P
Sbjct 123 LLFMGSEKFPDENEYSSYLSKHGGSSNAYTASQNTNYFFEVNHQHLFGALDRFSGFFSCP 182
Query 151 LFDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSL--AKGPMSRFATGNSATLSTNPKA 208
LF++ +KE+NA+++E++KN+ ND R + +SL K P +F+TGN TL T PK
Sbjct 183 LFNKDSTDKEINAVNSENKKNLQNDIWRIYQLDKSLTNTKHPYHKFSTGNIETLGTLPKE 242
Query 209 KGIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADWLGMVQCP 268
G+++ D L FH +Y +N++ + I L RE L+ +S D V
Sbjct 243 NGLNVRDELLKFHKNFY-SANLMKLCI----------LGREDLDTLSDWTYDLFKDVANN 291
Query 269 G---PMF-DTVKPFDHTNSGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQPTSVLTYLLE 324
G P++ + + +H K I ++ L ++F +P ++ +P +L++L+
Sbjct 292 GREVPLYAEPIMQPEHLQ--KIIQVRPVKDLKKLEISFTVPDMEEHWESKPPRILSHLIG 349
Query 325 YTGEGSLAKRLRLLGLADGISPVVDRNTIS---TLLGLKVDLTQKGATHRGLVLQEIFSY 381
+ G GSL L+ LG A+ +S +T+S + +DLT G TH V+ IF Y
Sbjct 350 HEGSGSLLAHLKKLGWANELS--AGGHTVSKGNAFFAVDIDLTDNGLTHYRDVIVLIFQY 407
Query 382 INFLRDHGVGHDLVSTLAQQSHVDFHTTQ---PSSSLMDEAARLAHNLLTYEPYHVVAGD 438
I L++ + + L S+ F Q PSS++ A L + Y P +
Sbjct 408 IEMLKNSLPQKWIFNELQDISNATFKFKQAGSPSSTVSSLAKCLEKD---YIPVSRILAM 464
Query 439 SLLIDADPRLTNQ 451
LL +P L Q
Sbjct 465 GLLTKYEPDLLTQ 477
> mmu:15925 Ide, 1300012G03Rik, 4833415K22Rik, AA675336, AI507533;
insulin degrading enzyme (EC:3.4.24.56); K01408 insulysin
[EC:3.4.24.56]
Length=1019
Score = 216 bits (549), Expect = 2e-55, Method: Compositional matrix adjust.
Identities = 123/369 (33%), Positives = 196/369 (53%), Gaps = 12/369 (3%)
Query 24 AIGALANDVLKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPG 83
AI + + ++K D R++R +L+NG+ + + P ++++ A+ + GSL DP ++PG
Sbjct 46 AIQRIEDQIVKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIPG 105
Query 84 LAHFLEHMLFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRF 143
L+HF EHMLFLGT KYP+ Y FL+++ G++NA+T E T ++ V+ E ALDRF
Sbjct 106 LSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRF 165
Query 144 SEFFKAPLFDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLA--KGPMSRFATGNSAT 201
++FF PLFD +++EVNA+D+EH+KN+ ND R + ++ K P S+F TGN T
Sbjct 166 AQFFLCPLFDASCKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYT 225
Query 202 LSTNPKAKGIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADW 261
L T P +GID+ + L FHS YY + M + SLD+ +L+ + + +
Sbjct 226 LETRPNQEGIDVREELLKFHSTYYSSNLMAICVLGRESLDDLTNLVVKLFSEVENKNV-- 283
Query 262 LGMVQCPGPMFDTVKPFDHTNSGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQPTSVLTY 321
P P F PF + + + +L+V F +P YK P L +
Sbjct 284 ------PLPEFPE-HPFQEEHLRQLYKIVPIKDIRNLYVTFPIPDLQQYYKSNPGHYLGH 336
Query 322 LLEYTGEGSLAKRLRLLGLADGISPVVDRNTISTLLG-LKVDLTQKGATHRGLVLQEIFS 380
L+ + G GSL L+ G + + + + VDLT++G H ++ +F
Sbjct 337 LIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQ 396
Query 381 YINFLRDHG 389
YI LR G
Sbjct 397 YIQKLRAEG 405
> dre:557565 nrd1, si:dkey-171o17.4; nardilysin (N-arginine dibasic
convertase) (EC:3.4.24.61)
Length=1061
Score = 214 bits (545), Expect = 5e-55, Method: Compositional matrix adjust.
Identities = 142/475 (29%), Positives = 227/475 (47%), Gaps = 56/475 (11%)
Query 26 GALANDVLKPEADYRDFRHYQLSNGMHA-------------------------------- 53
A +N ++K DY+ +R+ +LSNG+ A
Sbjct 38 AADSNTIIKSPNDYKTYRYIELSNGLKALLISDVSSQSESCRESVDKEVEEEGDRGSASD 97
Query 54 IAVHHPR-------SNEAGFAVAANTGSLYDPEDVPGLAHFLEHMLFLGTSKYPEPESYD 106
I+ H R ++ A+ + GS DP D+PGLAHFLEHM+F+G+ KYP +D
Sbjct 98 ISKHSERGKQSCRSEKQSAAALCISVGSFSDPADLPGLAHFLEHMVFMGSEKYPVENGFD 157
Query 107 SFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAPLFDRKYEEKEVNAIDA 166
+FL ++GG++NA TD E+T+F V EALDR+++FF PL ++EV A+D+
Sbjct 158 AFLKKHGGSDNASTDCERTIFQFDVQRKYLREALDRWAQFFICPLMIPDAVDREVEAVDS 217
Query 167 EHQKNIPNDDERAWYTIRSLAKG--PMSRFATGNSATLSTNPKAKGIDLVDRLRDFHSKY 224
E+Q P D R SLAK PMS+F GN+ TL P+ K I+ +RLRDF +Y
Sbjct 218 EYQMAQPLDSNRKEMLFGSLAKAGHPMSKFFWGNAQTLKQEPREKKINTYERLRDFWRRY 277
Query 225 YCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADWLGMVQCPGPMF-DTVKPFDHTNS 283
Y M S +LD E +RE I G+ P F D PFD +
Sbjct 278 YSAQYMTLAVQSKETLDTLEEWVREIFVQIPNN-----GL---PKADFSDLQDPFDTPDF 329
Query 284 GKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQPTSVLTYLLEYTGEGS----LAKRLRLLG 339
K + +L +++ LPP Y+ +P +++L+ + G GS L KR L
Sbjct 330 CKLYRVVPVQKVHALTISWALPPQAKHYRVKPLHYISWLIGHEGVGSVLSLLRKRCWALS 389
Query 340 LADGISPV-VDRNTISTLLGLKVDLTQKGATHRGLVLQEIFSYINFLRDHGVGHDLVSTL 398
L G S D+N+ ++ + + L+ +G + V+ IF Y+ L+ G + +
Sbjct 390 LFGGNSESGFDQNSTYSIFSISITLSDEGLQNFLQVIHIIFQYLKMLQSVGPQQRIYEEI 449
Query 399 AQQSHVDFHTTQPSSSLMDEAARLAHNLLTYEPYHVVAGDSLLIDADPRLTNQLL 453
+ +FH Q + ++ A ++ N+ + H + GD L+ D +P ++ ++
Sbjct 450 QKIEANEFH-YQEQTEPIEFVANMSENMQLFPKEHFLCGDQLMFDFNPEASHCVI 503
> ath:AT2G41790 peptidase M16 family protein / insulinase family
protein; K01408 insulysin [EC:3.4.24.56]
Length=970
Score = 211 bits (538), Expect = 4e-54, Method: Compositional matrix adjust.
Identities = 131/429 (30%), Positives = 218/429 (50%), Gaps = 19/429 (4%)
Query 31 DVLKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEH 90
++LKP D R++R L N + + + P +++ +++ + GS DP+ + GLAHFLEH
Sbjct 14 EILKPRTDNREYRMIVLKNLLQVLLISDPDTDKCAASMSVSVGSFSDPQGLEGLAHFLEH 73
Query 91 MLFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAP 150
MLF + KYPE +SY ++T++GG+ NAYT E+T + V F+EALDRF++FF P
Sbjct 74 MLFYASEKYPEEDSYSKYITEHGGSTNAYTASEETNYHFDVNADCFDEALDRFAQFFIKP 133
Query 151 LFDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLAKG--PMSRFATGNSATLSTNPKA 208
L +E+ A+D+E+QKN+ +D R + L+K P +F+TGN TL P+A
Sbjct 134 LMSADATMREIKAVDSENQKNLLSDGWRIRQLQKHLSKEDHPYHKFSTGNMDTLHVRPQA 193
Query 209 KGIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADWLGMVQCP 268
KG+D L F+ ++Y + M V SLD+ + L+ + I + + + P
Sbjct 194 KGVDTRSELIKFYEEHYSANIMHLVVYGKESLDKIQDLVERMFQEIQNTNK---VVPRFP 250
Query 269 GPMFDTVKPFDHTNSGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQPTSVLTYLLEYTGE 328
G +P + + L V++ + P++ Y + P+ L +L+ + GE
Sbjct 251 G------QPCTADHLQILVKAIPIKQGHKLGVSWPVTPSIHHYDEAPSQYLGHLIGHEGE 304
Query 329 GSLAKRLRLLGLADGISPVVDRNTIS-TLLGLKVDLTQKGATHRGLVLQEIFSYINFLRD 387
GSL L+ LG A G+S T+ + + +DLT G H +L +F+YI L+
Sbjct 305 GSLFHALKTLGWATGLSAGEGEWTLDYSFFKVSIDLTDAGHEHMQEILGLLFNYIQLLQQ 364
Query 388 HGVGHDLVSTLAQQSHVDFH---TTQPSSSLMDEAARLAHNLLTYEPYHVVAGDSLLIDA 444
GV + L+ FH P S ++D +A N+ Y + G SL
Sbjct 365 TGVCQWIFDELSAICETKFHYQDKIPPMSYIVD----IASNMQIYPTKDWLVGSSLPTKF 420
Query 445 DPRLTNQLL 453
+P + +++
Sbjct 421 NPAIVQKVV 429
> cel:C02G6.2 hypothetical protein; K01408 insulysin [EC:3.4.24.56]
Length=816
Score = 204 bits (520), Expect = 4e-52, Method: Compositional matrix adjust.
Identities = 137/434 (31%), Positives = 216/434 (49%), Gaps = 26/434 (5%)
Query 30 NDVLKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLE 89
N ++K D R+ R +L+NG+ + V P ++++ ++A G L DP ++PGLAHF E
Sbjct 14 NSIVKGPQDERECRGLELTNGLRVLLVSDPTTDKSAVSLAVKAGHLMDPWELPGLAHFCE 73
Query 90 HMLFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKA 149
HMLFLGTSKYP + FL+ N G+ NA T+ + T + V ALDRF +FF
Sbjct 74 HMLFLGTSKYPLENEFTKFLSDNAGSYNACTEPDHTYYHFDVKPDQLYGALDRFVQFFLC 133
Query 150 PLFDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLAK-GPMSR-FATGNSATLSTNPK 207
P F + E+EV A+D+EH N+ +D R RSL++ G +R F TGN TL + +
Sbjct 134 PQFTKSATEREVCAVDSEHLSNLNSDYWRILQVDRSLSRPGHDNRKFCTGNKKTLLEDAR 193
Query 208 AKGIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIR----EKLEGISAGHADWLG 263
KGI+ D L +F+ K+Y + M I SLD ES +R + ++ A W
Sbjct 194 KKGIEPRDALLEFYKKWYSSNIMTCCIIGKESLDVLESYLRTLEFDAIQNKKAESKVWAE 253
Query 264 MVQCPGPMFDTVKPFDHTNSGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQPTSVLTYLL 323
P + K I + + + + F P Y QP + +L+
Sbjct 254 FQYGPDQL------------AKKIDVVPIKDKKLVSIIFPFPDLNNEYLSQPGHYIAHLI 301
Query 324 EYTGEGSLAKRLRLLGLADGISPVVDRNTISTLLG---LKVDLTQKGATHRGLVLQEIFS 380
+ G GS++ L+ LG A + P + TI+ G + +DL+ +G H ++Q +F+
Sbjct 302 GHKGPGSISSELKRLGWASSLKP--ESKTIAAGFGYFNVTMDLSTEGLEHVDEIIQLMFN 359
Query 381 YINFLRDHGVGHDLVSTLAQQSHVDFHTTQPSSSLMDEAARLAHNLLTYEPY-HVVAGDS 439
YI L+ G + LA+ S ++F + L A ++A N L Y P+ H+++
Sbjct 360 YIGMLQSAGPQQWIHEELAELSAIEFR-FKDREPLTKNAIKVARN-LQYIPFEHILSSRY 417
Query 440 LLIDADPRLTNQLL 453
LL +P +LL
Sbjct 418 LLTKYNPERIKELL 431
> dre:565850 fk24c07; wu:fk24c07; K01411 nardilysin [EC:3.4.24.61]
Length=1091
Score = 203 bits (517), Expect = 9e-52, Method: Compositional matrix adjust.
Identities = 126/399 (31%), Positives = 200/399 (50%), Gaps = 17/399 (4%)
Query 63 EAGFAVAANTGSLYDPEDVPGLAHFLEHMLFLGTSKYPEPESYDSFLTQNGGANNAYTDE 122
++ A+ GS DP D+PGLAHFLEHM+F+G+ KYP +D+FL ++GG++NA TD
Sbjct 145 QSAAALCIGVGSFSDPNDLPGLAHFLEHMVFMGSEKYPSENGFDAFLKKHGGSDNASTDC 204
Query 123 EKTVFFNKVTDSAFEEALDRFSEFFKAPLFDRKYEEKEVNAIDAEHQKNIPNDDERAWYT 182
E+T+F V F+EALDR+++FF PL ++EV A+D+E+Q P+D R
Sbjct 205 ERTIFQFDVQRKRFKEALDRWAQFFICPLMIEDAIDREVEAVDSEYQLAKPSDSHRKEML 264
Query 183 IRSLAKG--PMSRFATGNSATLSTNPKAKGIDLVDRLRDFHSKYYCGSNMVAVTISPRSL 240
SLAK PMS+F GN+ TL T PK K I++ RLR+F ++Y M S SL
Sbjct 265 FGSLAKPDHPMSKFCWGNAQTLKTEPKEKNINVYKRLREFWKRHYSAHYMTLAVQSKESL 324
Query 241 DEQESLIREKLEGISAGHADWLGMVQCPGPMF-DTVKPFDHTNSGKFIHLQSFSSQPSLW 299
D E +RE + G ++ P F D + PF+ K + +L
Sbjct 325 DTLEEWVREIFSQVPNN-----GQLK---PDFSDKLNPFETPAFNKLYRVVPVRKVHALT 376
Query 300 VAFGLPPTLTSYKKQPTSVLTYLLEYTGEGSLAKRLR----LLGLADGISPV-VDRNTIS 354
+ + LPP Y+ +P + +L+ + G GS+ LR L L G S D+NT
Sbjct 377 ITWALPPQEKHYRVKPLHYIAWLIGHEGTGSILSMLRRKCWALALFGGNSETGFDQNTTY 436
Query 355 TLLGLKVDLTQKGATHRGLVLQEIFSYINFLRDHGVGHDLVSTLAQQSHVDFHTTQPSSS 414
++ + + LT +G + V +F Y+ L+ G + + + +FH Q +
Sbjct 437 SIFSISITLTDEGFQNFYEVAHLVFQYLKMLQTLGPQQRIYEEIQKIEANEFH-YQEQTD 495
Query 415 LMDEAARLAHNLLTYEPYHVVAGDSLLIDADPRLTNQLL 453
++ + N+ + + GD L+ + P + + L
Sbjct 496 PIEYVEDICENMQLFPKEDFLTGDQLMFEFKPEVISAAL 534
> mmu:230598 Nrd1, 2600011I06Rik, AI875733, MGC25477, NRD-C; nardilysin,
N-arginine dibasic convertase, NRD convertase 1 (EC:3.4.24.61);
K01411 nardilysin [EC:3.4.24.61]
Length=1161
Score = 200 bits (509), Expect = 7e-51, Method: Compositional matrix adjust.
Identities = 127/400 (31%), Positives = 199/400 (49%), Gaps = 17/400 (4%)
Query 62 NEAGFAVAANTGSLYDPEDVPGLAHFLEHMLFLGTSKYPEPESYDSFLTQNGGANNAYTD 121
++ A+ GS DP+D+PGLAHFLEHM+F+G+ KYP+ +D+FL ++GG++NA TD
Sbjct 220 KQSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTD 279
Query 122 EEKTVFFNKVTDSAFEEALDRFSEFFKAPLFDRKYEEKEVNAIDAEHQKNIPNDDERAWY 181
E+TVF V F+EALDR+++FF PL R ++EV A+D+E+Q P+D R
Sbjct 280 CERTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEM 339
Query 182 TIRSLAKG--PMSRFATGNSATLSTNPKAKGIDLVDRLRDFHSKYYCGSNMVAVTISPRS 239
SLA+ PM +F GN+ TL PK ID RLR+F +YY M V S +
Sbjct 340 LFGSLARPGHPMGKFFWGNAETLKHEPKKNNIDTHARLREFWMRYYSAHYMTLVVQSKET 399
Query 240 LDEQESLIREKLEGISAGHADWLGMVQCPGPMFDTVK-PFDHTNSGKFIHLQSFSSQPSL 298
LD E + E I G+ P P F + PFD K + +L
Sbjct 400 LDTLEKWVTEIFSQIPNN-----GL---PKPNFSHLTDPFDTPAFNKLYRVVPIRKIHAL 451
Query 299 WVAFGLPPTLTSYKKQPTSVLTYLLEYTGEGSLAKRLR----LLGLADGISPV-VDRNTI 353
+ + LPP Y+ +P +++L+ + G+GS+ LR L L G ++N+
Sbjct 452 TITWALPPQQQHYRVKPLHYISWLVGHEGKGSILSYLRKKCWALALFGGNGETGFEQNST 511
Query 354 STLLGLKVDLTQKGATHRGLVLQEIFSYINFLRDHGVGHDLVSTLAQQSHVDFHTTQPSS 413
++ + + LT +G H V +F Y+ L+ G + + + +FH Q +
Sbjct 512 YSVFSISITLTDEGYEHFYEVAHTVFQYLKMLQKLGPEKRVFEEIQKIEDNEFH-YQEQT 570
Query 414 SLMDEAARLAHNLLTYEPYHVVAGDSLLIDADPRLTNQLL 453
++ + N+ Y + GD LL + P + + L
Sbjct 571 DPVEYVENMCENMQLYPRQDFLTGDQLLFEYKPEVIAEAL 610
> ath:AT1G06900 catalytic/ metal ion binding / metalloendopeptidase/
zinc ion binding; K01411 nardilysin [EC:3.4.24.61]
Length=1024
Score = 200 bits (509), Expect = 8e-51, Method: Compositional matrix adjust.
Identities = 132/403 (32%), Positives = 209/403 (51%), Gaps = 23/403 (5%)
Query 60 RSNEAGFAVAANTGSLYDPEDVPGLAHFLEHMLFLGTSKYPEPESYDSFLTQNGGANNAY 119
++ +A A+ + GS DP + GLAHFLEHMLF+G++++P+ YDS+L+++GG++NAY
Sbjct 103 QTKKAAAAMCVSMGSFLDPPEAQGLAHFLEHMLFMGSTEFPDENEYDSYLSKHGGSSNAY 162
Query 120 TDEEKTVFFNKVTDSAFEEALDRFSEFFKAPLFDRKYEEKEVNAIDAEHQKNIPNDDER- 178
T+ E T + +V + AL RFS+FF APL + E+EV A+D+E + + ND R
Sbjct 163 TEMEHTCYHFEVKREFLQGALKRFSQFFVAPLMKTEAMEREVLAVDSEFNQALQNDACRL 222
Query 179 AWYTIRSLAKG-PMSRFATGNSATLSTNPKAKGIDLVDRLRDFHSKYYCGSNMVAVTISP 237
+ AKG P +RFA GN +LS G+DL + + + +YY G M V I
Sbjct 223 QQLQCYTSAKGHPFNRFAWGNKKSLS-GAMENGVDLRECIVKLYKEYYHGGLMKLVVIGG 281
Query 238 RSLDEQESLIREKLEGISAGHADWLGMVQCPGPMFDTVKPFDHTNSGKFIHLQSFSSQPS 297
SLD ES + E + G + ++ GP++ GK L++
Sbjct 282 ESLDMLESWVVELFGDVKNG-SKIRPTLEAEGPIW---------KGGKLYRLEAVKDVHI 331
Query 298 LWVAFGLPPTLTSYKKQPTSVLTYLLEYTGEGSLAKRLRLLGLADGISPVV-----DRNT 352
L + + LPP ++Y K+P L +LL + G GSL L+ G A +S V +R++
Sbjct 332 LDLTWTLPPLRSAYVKKPEDYLAHLLGHEGRGSLHSFLKAKGWATSLSAGVGDDGINRSS 391
Query 353 ISTLLGLKVDLTQKGATHRGLVLQEIFSYINFLRDHGVGHDLVSTLAQQSHVDFH--TTQ 410
++ + G+ + LT G ++ I+ Y+ LRD + L ++DF Q
Sbjct 392 LAYVFGMSIHLTDSGLEKIYDIIGYIYQYLKLLRDVSPQEWIFKELQDIGNMDFRFAEEQ 451
Query 411 PSSSLMDEAARLAHNLLTYEPYHVVAGDSLLIDADPRLTNQLL 453
P+ D AA L+ N+L Y HV+ GD + DP+L L+
Sbjct 452 PAD---DYAAELSENMLAYPVEHVIYGDYVYQTWDPKLIEDLM 491
Score = 32.7 bits (73), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 0/38 (0%)
Query 22 LSAIGALANDVLKPEADYRDFRHYQLSNGMHAIAVHHP 59
+ ++ AL N V+K D R +R +L NG+ A+ +H P
Sbjct 4 MKSVSALDNVVVKSPNDRRLYRVIELENGLCALLIHDP 41
> hsa:4898 NRD1, hNRD1, hNRD2; nardilysin (N-arginine dibasic
convertase) (EC:3.4.24.61); K01411 nardilysin [EC:3.4.24.61]
Length=1151
Score = 199 bits (507), Expect = 1e-50, Method: Compositional matrix adjust.
Identities = 126/399 (31%), Positives = 200/399 (50%), Gaps = 17/399 (4%)
Query 63 EAGFAVAANTGSLYDPEDVPGLAHFLEHMLFLGTSKYPEPESYDSFLTQNGGANNAYTDE 122
++ A+ GS DP+D+PGLAHFLEHM+F+G+ KYP+ +D+FL ++GG++NA TD
Sbjct 210 QSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDC 269
Query 123 EKTVFFNKVTDSAFEEALDRFSEFFKAPLFDRKYEEKEVNAIDAEHQKNIPNDDERAWYT 182
E+TVF V F+EALDR+++FF PL R ++EV A+D+E+Q P+D R
Sbjct 270 ERTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEML 329
Query 183 IRSLAKG--PMSRFATGNSATLSTNPKAKGIDLVDRLRDFHSKYYCGSNMVAVTISPRSL 240
SLA+ PM +F GN+ TL P+ ID RLR+F +YY M V S +L
Sbjct 330 FGSLARPGHPMGKFFWGNAETLKHEPRKNNIDTHARLREFWMRYYSSHYMTLVVQSKETL 389
Query 241 DEQESLIREKLEGISAGHADWLGMVQCPGPMFDTVK-PFDHTNSGKFIHLQSFSSQPSLW 299
D E + E I G+ P P F + PFD K + +L
Sbjct 390 DTLEKWVTEIFSQIPNN-----GL---PRPNFGHLTDPFDTPAFNKLYRVVPIRKIHALT 441
Query 300 VAFGLPPTLTSYKKQPTSVLTYLLEYTGEGS----LAKRLRLLGLADGISPV-VDRNTIS 354
+ + LPP Y+ +P +++L+ + G+GS L K+ L L G ++N+
Sbjct 442 ITWALPPQQQHYRVKPLHYISWLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTY 501
Query 355 TLLGLKVDLTQKGATHRGLVLQEIFSYINFLRDHGVGHDLVSTLAQQSHVDFHTTQPSSS 414
++ + + LT +G H V +F Y+ L+ G + + + +FH Q +
Sbjct 502 SVFSISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFH-YQEQTD 560
Query 415 LMDEAARLAHNLLTYEPYHVVAGDSLLIDADPRLTNQLL 453
++ + N+ Y ++ GD LL + P + + L
Sbjct 561 PVEYVENMCENMQLYPLQDILTGDQLLFEYKPEVIGEAL 599
> tgo:TGME49_069890 M16 family peptidase, putative (EC:3.4.24.56)
Length=941
Score = 196 bits (499), Expect = 1e-49, Method: Compositional matrix adjust.
Identities = 133/445 (29%), Positives = 211/445 (47%), Gaps = 12/445 (2%)
Query 12 NAASVGLCVGLSAIGALANDVLKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAAN 71
A +V L + ++ +L V KP D R++R+ +L N + A+ V P +EA ++
Sbjct 5 RAVTVSLSWVILSLLSLLFPVRKPRNDSRNYRYIELPNELRALLVSDPECDEAAASMRVG 64
Query 72 TGSLYDPEDVPGLAHFLEHMLFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKV 131
GS+ DP +PGLAHF EHMLF G+ ++P + F+ +GG NA+T + TVF +
Sbjct 65 VGSMSDPPKIPGLAHFTEHMLFQGSKRFPGTHDFFDFVHNHGGYTNAFTSKFSTVFSFSI 124
Query 132 TDSAFEEALDRFSEFFKAPLFDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLAK-GP 190
E LDR ++ F APL + KEVNA+ +E+ ++ +D R + IR AK GP
Sbjct 125 GPGFLEPGLDRLADLFSAPLLKSENLLKEVNAVHSEYIIDLTDDGRRKHHLIRQTAKGGP 184
Query 191 MSRFATGNSATLSTNPKAKGIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREK 250
S F GN +L K +GID V +R+FH+K+Y + M + SLD ES +R+
Sbjct 185 FSNFTVGNLESLMERTKQQGIDPVKAMREFHNKWYSSNLMTLAVVGRESLDVLESHVRKH 244
Query 251 LEGISAGHADWLGMVQCPGPMFDTVKPFDHTNSGKFIHLQSFSSQPSLWVAFGLPPTLTS 310
+ G +C + P D G + + F LPP +
Sbjct 245 FGNVPNGRVTPPVFEECS----EAFIPLDPNELGTETLVVPEADLHDATFVFYLPPQAKN 300
Query 311 YKKQPTSVLTYLLEYTGEGSLAKRLRLLGLADGISPVVDRNTISTLLGLKVDLTQKGATH 370
++ +P ++ +LE+ G SL+ +L+ GL + + T+L + V LT+ G +
Sbjct 301 WRSKPLQFISEMLEHEGPTSLSSKLKREGLITSLVTDYWSPELCTVLQVNVRLTEGGRSK 360
Query 371 RGLVLQEIFSYINFLRDHGVGHD---LVSTLAQQSHVDF-HTTQPSSSLMDEAARLAHNL 426
V + + FLR+ GV V+ +A+ + F P + R L
Sbjct 361 ES-VYKIGHALFTFLRNLGVSRPERWRVTEMAKIRQLGFAFADMPDPYAL--TVRAVEGL 417
Query 427 LTYEPYHVVAGDSLLIDADPRLTNQ 451
Y P V+AGD L+ DP + Q
Sbjct 418 NYYTPEEVIAGDRLIYHFDPDIIQQ 442
> cel:Y70C5C.1 hypothetical protein; K01408 insulysin [EC:3.4.24.56]
Length=985
Score = 192 bits (487), Expect = 3e-48, Method: Compositional matrix adjust.
Identities = 137/435 (31%), Positives = 203/435 (46%), Gaps = 27/435 (6%)
Query 32 VLKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEHM 91
+LK D R++R +L+NG+ + V P ++++ A+ N G L DP ++PGLAHF EHM
Sbjct 16 ILKGAQDEREYRGLELTNGIRVLLVSDPTTDKSAAALDVNVGHLMDPWELPGLAHFCEHM 75
Query 92 LFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAPL 151
LFLGT+KYP Y FLT + G NA T + T +F +V ALDRF +FF +P
Sbjct 76 LFLGTAKYPSENEYFKFLTAHAGRANANTATDHTNYFFEVKPDQLPGALDRFVQFFLSPQ 135
Query 152 FDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLAK--GPMSRFATGNSATLSTNPKAK 209
F E+EV A+D+EH N+ ND R RS AK +F TGN TL + + +
Sbjct 136 FTESATEREVCAVDSEHSNNLNNDAWRFLQVHRSCAKPGHDYGKFGTGNKKTLLEDARKQ 195
Query 210 GIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADWLGMVQCPG 269
GI+ D L FH K+Y + M I SLD ES L D + +
Sbjct 196 GIEPRDALLQFHKKWYSSNIMTCCIIGKESLDVLESY----LGTFEFAAIDNKKLERQIW 251
Query 270 PMFDTVKPFDHTNSGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQPTSVLTYLLEYTGEG 329
F PF GK I + + ++F P + QP +++L+ + G G
Sbjct 252 KEF----PFGPEQLGKRIDVVPIKDTRQISISFPFPDLTGEFLSQPEHYISHLIGHEGHG 307
Query 330 SLAKRLRLLGLADGISP--VVDRNTISTLLGLKVDLTQKGATHRGLVLQEIFSYINFLRD 387
SL L+ LG + VV + ++L+ +G H ++Q +F+YI ++
Sbjct 308 SLLSELKRLGWVVSLQSGYVVQAAGFGN-FQVGIELSTEGLEHVDEIIQLMFNYIGMMQS 366
Query 388 HGVGHDLVSTLAQQSHVDFH---TTQPSSSLMDEAARLA-----------HNLLTYEPYH 433
G + LA+ V F QP + AARL H L YEP
Sbjct 367 SGPKQWVHEELAELRAVTFRFKDKEQPMAMASCVAARLQRIPFKHVLSSPHLLTNYEPVR 426
Query 434 VVAGDSLLIDADPRL 448
+ S+LI ++ ++
Sbjct 427 IKELLSMLIPSNMKI 441
> cel:C28F5.4 hypothetical protein; K01408 insulysin [EC:3.4.24.56]
Length=856
Score = 188 bits (477), Expect = 5e-47, Method: Compositional matrix adjust.
Identities = 129/411 (31%), Positives = 196/411 (47%), Gaps = 45/411 (10%)
Query 30 NDVLKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLE 89
+ ++K D + +R +L+NG+ + V ++ + A+ G L DP ++PGLAHF E
Sbjct 15 DSIVKGSQDTKKYRGLELTNGLRVLLVSDSKTRVSAVALDVKVGHLMDPWELPGLAHFCE 74
Query 90 HMLFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKA 149
HMLFLGT+KYP Y +L N G +NAYTD + T + +V ALDRF++FF
Sbjct 75 HMLFLGTAKYPSEREYFKYLAANNGDSNAYTDTDHTNYSFEVRSEKLYGALDRFAQFFLD 134
Query 150 PLFDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLAK--GPMSRFATGNSATLSTNPK 207
P F E+EV A++ E+ + D R RSL+K S+FA GN TL +P+
Sbjct 135 PQFTESATEREVCAVNCEYLDKVNEDFWRCLQVERSLSKPGHDYSKFAIGNKKTLLEDPR 194
Query 208 AKGIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADWLGMVQC 267
KGI+ D L DF+ +Y M + SLD ES +LG +
Sbjct 195 TKGIEPRDVLLDFYKNWYSSDIMTCCIVGKESLDVLES---------------YLGSFK- 238
Query 268 PGPMFDTVK------------PFDHTNSGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQP 315
FD +K PF K I + + + + F P + QP
Sbjct 239 ----FDAIKNTRKERKIWKDSPFGPDQLAKRIEIVPIQNTGQVSIKFPFPDLNGEFLSQP 294
Query 316 TSVLTYLLEYTGEGSLAKRLRLLGLADGISPVVDRNTISTLLG---LKVDLTQKGATHRG 372
+ +L+ + G GSL L+ LG IS D +TI++ G + +DL+ +G H
Sbjct 295 GDYIAHLIGHEGPGSLLSELKRLGWV--ISLEADNHTIASGFGVFSVTMDLSTEGLEHVD 352
Query 373 LVLQEIFSYINFLRDHGVGHDLVSTLAQQSHVDF------HTTQPSSSLMD 417
V+Q +F++I FL+ G + LA+ + VDF HT + +S L +
Sbjct 353 DVIQLVFNFIGFLKSSGPQKWIHDELAELNAVDFRFDDVKHTMEKASILAE 403
> cel:F44E7.4 hypothetical protein; K01408 insulysin [EC:3.4.24.56]
Length=1051
Score = 187 bits (475), Expect = 8e-47, Method: Compositional matrix adjust.
Identities = 132/435 (30%), Positives = 204/435 (46%), Gaps = 32/435 (7%)
Query 32 VLKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEHM 91
++K D R++R +L+NG+ + V P ++++ A+ G L DP ++PGLAHF EHM
Sbjct 75 IVKGAQDAREYRGLELTNGIRVLLVSDPTTDKSAAALDVKVGHLMDPWELPGLAHFCEHM 134
Query 92 LFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAPL 151
LFLGT+KYP Y FL + G++NAYT + T + V ALDRF +FF +P
Sbjct 135 LFLGTAKYPSENEYSKFLAAHAGSSNAYTSSDHTNYHFDVKPDQLPGALDRFVQFFLSPQ 194
Query 152 FDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLAK--GPMSRFATGNSATLSTNPKAK 209
F E+EV A+D+EH N+ ND R RS +K +F TGN TL + + K
Sbjct 195 FTESATEREVCAVDSEHSNNLNNDLWRFLQVDRSRSKPGHDYGKFGTGNKQTLLEDARKK 254
Query 210 GIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQES----LIREKLEGISAGHADWLGMV 265
GI+ D L FH K+Y M + L+ ES L + +E W
Sbjct 255 GIEPRDALLQFHKKWYSSDIMTCCIVGKEPLNVLESYLGTLEFDAIENKKVERKVWEEF- 313
Query 266 QCPGPMFDTVKPFDHTNSGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQPTSVLTYLLEY 325
P+ K I + + ++F P + QP +++L+ +
Sbjct 314 -----------PYGPDQLAKRIDVVPIKDTRLVSISFPFPDLNGEFLSQPGHYISHLIGH 362
Query 326 TGEGSLAKRLRLLGLADGISPVVDRNTISTLLG---LKVDLTQKGATHRGLVLQEIFSYI 382
G GSL L+ LG + D +T + G + +DL+ +G H ++Q +F+YI
Sbjct 363 EGPGSLLSELKRLGWVSSLQS--DSHTQAAGFGVYNVTMDLSTEGLEHVDEIIQLMFNYI 420
Query 383 NFLRDHGVGHDLVSTLAQQSHVDFH---TTQPSSSLMDEAARLAHNLLTYEPY-HVVAGD 438
L+ G + LA+ S V F QP + ++ AA L Y P+ H+++
Sbjct 421 GMLQSAGPKQWVHDELAELSAVKFRFKDKEQPMTMAINVAAS-----LQYIPFEHILSSR 475
Query 439 SLLIDADPRLTNQLL 453
LL +P +LL
Sbjct 476 YLLTKYEPERIKELL 490
> cpv:cgd2_920 peptidase'insulinase-like peptidase'
Length=1028
Score = 185 bits (469), Expect = 3e-46, Method: Compositional matrix adjust.
Identities = 122/392 (31%), Positives = 189/392 (48%), Gaps = 8/392 (2%)
Query 29 ANDVLKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFL 88
+D++ PE + R +R +L NG+ A V + +G + G++Y P+++ GLAHFL
Sbjct 14 VDDIVLPECEDRKYRALELKNGLTAFLVSDKETKTSGCCLTVYIGAMYSPKNLNGLAHFL 73
Query 89 EHMLFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFK 148
EHMLF GT KYP + Y F+ +GG + T T ++ ++ ++AF EALDRFS FF
Sbjct 74 EHMLFCGTKKYPNVDEYQKFIASHGGKRHGSTTRSTTTYYFEIKNNAFNEALDRFSSFFT 133
Query 149 APLFDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLAKG--PMSRFATGNSATLSTNP 206
PLF + EKEV+AI+ E +D+ ++ + L+ P++ F TGN TL P
Sbjct 134 EPLFCKDMTEKEVSAIENEFHLKYHSDERVRFHLLGQLSNKSHPLNCFTTGNKETLEFKP 193
Query 207 KAKGIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADWLGMVQ 266
K GI+L L F+S YY + M + LD E E I + +
Sbjct 194 KKLGINLHSELLKFYSSYYSSNIMSIILYGKEDLDTLEKYTIEYFSKIPNHQVNCFDYTK 253
Query 267 CPGPMFDTVKPFD-HTNSGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQPTSVLTYLLEY 325
+F + P+ T+ GK I L + + L + F LPP + + ++ +
Sbjct 254 ----IFMEIPPYTRETSIGKIIKLIPYETDKRLKIYFPLPPLDKYNDSCAPAYIANIIGH 309
Query 326 TGEGSLAKRLRLLGLADGISPVVDRNTISTLLGLKVDLTQKGATHRGLVLQEIFSYINFL 385
GEG ++ LR LA G S + L V LT +G + G VL+ IF+++
Sbjct 310 KGEGGISSILRAKKLATGASFAITNEDPCALAQFGVVLTDEGYNNIGQVLEIIFNFLVLF 369
Query 386 RDHGVGHDLVSTLAQQSHVDFHTTQPSSSLMD 417
+ V +LV + F T QP S+ D
Sbjct 370 KATPVIPELVDEFIGITRAGF-TYQPKFSIRD 400
> eco:b2821 ptrA, ECK2817, JW2789, ptr; protease III (EC:3.4.24.55);
K01407 protease III [EC:3.4.24.55]
Length=962
Score = 180 bits (457), Expect = 9e-45, Method: Compositional matrix adjust.
Identities = 126/385 (32%), Positives = 191/385 (49%), Gaps = 26/385 (6%)
Query 32 VLKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEHM 91
+ K + D R ++ +L NGM + V P++ ++ A+ GSL DPE GLAH+LEHM
Sbjct 34 IRKSDKDNRQYQAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHM 93
Query 92 LFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAPL 151
+G+ KYP+ +S +L +GG++NA T +T F+ +V + A A+DR ++ PL
Sbjct 94 SLMGSKKYPQADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPL 153
Query 152 FDRKYEEKEVNAIDAEHQKNIPNDDER-AWYTIRSLAKG-PMSRFATGNSATLSTNPKAK 209
D+KY E+E NA++AE D R A + ++ P S+F+ GN TLS P
Sbjct 154 LDKKYAERERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKP--- 210
Query 210 GIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADWLGMV---Q 266
G + L+DFH KYY + M AV S + L E ++ AD G V +
Sbjct 211 GNPVQQALKDFHEKYYSANLMKAVIYSNKPLPE-----------LAKMAADTFGRVPNKE 259
Query 267 CPGPMFDTVKPFDHTNSGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQPTSVLTYLLEYT 326
P TV G IH + L V F + ++ + ++TYL+
Sbjct 260 SKKPEI-TVPVVTDAQKGIIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNR 318
Query 327 GEGSLAKRLRLLGLADGIS----PVVDRNTISTLLGLKVDLTQKGATHRGLVLQEIFSYI 382
G+L+ L+ GL +GIS P+V+ N S +L + LT KG +R V+ IFSY+
Sbjct 319 SPGTLSDWLQKQGLVEGISANSDPIVNGN--SGVLAISASLTDKGLANRDQVVAAIFSYL 376
Query 383 NFLRDHGVGHDLVSTLAQQSHVDFH 407
N LR+ G+ LA +DF
Sbjct 377 NLLREKGIDKQYFDELANVLDIDFR 401
> cel:C02G6.1 hypothetical protein; K01408 insulysin [EC:3.4.24.56]
Length=980
Score = 180 bits (456), Expect = 1e-44, Method: Compositional matrix adjust.
Identities = 135/433 (31%), Positives = 205/433 (47%), Gaps = 51/433 (11%)
Query 30 NDVLKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLE 89
+ ++K D R++R +L+NG+ + V P ++++ A+ G L DP ++PGLAHF E
Sbjct 14 DSIVKGAQDDREYRGLELTNGIRVLLVSDPTTDKSAAALDVKVGHLMDPWELPGLAHFCE 73
Query 90 HMLFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKA 149
HMLFLGT+KYP Y FLT N G NA T + T + V ALDRF +FF +
Sbjct 74 HMLFLGTAKYPTENEYSKFLTDNAGHRNAVTASDHTNYHFDVKPDQLRGALDRFVQFFLS 133
Query 150 PLFDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLAK--GPMSRFATGNSATLSTNPK 207
P F E+EV A+D+EH N+ ND R RSL+K ++F TGN TL +
Sbjct 134 PQFTESATEREVCAVDSEHSNNLNNDLWRLSQVDRSLSKPGHDYAKFGTGNKKTLLEEAR 193
Query 208 AKGIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADWLGMVQC 267
KG++ D L F+ K+Y + M I SLD +S ++ LE
Sbjct 194 KKGVEPRDALLQFYKKWYSSNIMTCCIIGKESLDVLQSHLK-TLE--------------- 237
Query 268 PGPMFDTVKPFDHTNSGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQPTSVLTYLLEYTG 327
FDT++ K + + ++ P +G P L K+ +L+ + G
Sbjct 238 ----FDTIE-------NKKVERKVWNENP-----YG-PEQLG--KRIDRKFFAHLIRHKG 278
Query 328 EGSLAKRLRLLGLADGISPVVDRNTIST---LLGLKVDLTQKGATHRGLVLQEIFSYINF 384
GSL L+ LG + + D NTI+ +L + +DL+ G + ++Q + +YI
Sbjct 279 PGSLLVELKRLGWVNSLKS--DSNTIAAGFGILNVTMDLSTGGLENVDEIIQLMLNYIGM 336
Query 385 LRDHGVGHDLVSTLAQQSHVDFH---TTQPSSSLMDEAARLAHNLLTYEPY-HVVAGDSL 440
L+ G + LA S V F QP ++ AA L Y P H+++ L
Sbjct 337 LKSFGPQQWIHDELADLSDVKFRFKDKEQPMKMAINIAASLQ-----YIPIEHILSSRYL 391
Query 441 LIDADPRLTNQLL 453
L +P +LL
Sbjct 392 LTKYEPERIKELL 404
> ath:AT3G57470 peptidase M16 family protein / insulinase family
protein; K01408 insulysin [EC:3.4.24.56]
Length=891
Score = 165 bits (417), Expect = 4e-40, Method: Compositional matrix adjust.
Identities = 106/366 (28%), Positives = 179/366 (48%), Gaps = 13/366 (3%)
Query 91 MLFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAP 150
MLF + KYPE +SY ++T++GG+ NAYT E T + + +F EALDRF++FF P
Sbjct 1 MLFYASEKYPEEDSYSKYITEHGGSTNAYTSSEDTNYHFDINTDSFYEALDRFAQFFIQP 60
Query 151 LFDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLAKG--PMSRFATGNSATLSTNPKA 208
L +E+ A+D+EHQ N+ +D R + L++ P +F+TGN TL P+
Sbjct 61 LMSTDATMREIKAVDSEHQNNLLSDSWRMAQLQKHLSREDHPYHKFSTGNMDTLHVRPEE 120
Query 209 KGIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADWLGMVQCP 268
G+D L F+ ++Y + M V +LD+ + L+ +GI + G+ + P
Sbjct 121 NGVDTRSELIKFYDEHYSANIMHLVVYGKENLDKTQGLVEALFQGIRNTNQ---GIPRFP 177
Query 269 GPMFDTVKPFDHTNSGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQPTSVLTYLLEYTGE 328
G +P + + L V++ + P+++ Y++ P L L+ + GE
Sbjct 178 G------QPCTLDHLQVLVKAVPIMQGHELSVSWPVTPSISHYEEAPCRYLGDLIGHEGE 231
Query 329 GSLAKRLRLLGLADGI-SPVVDRNTISTLLGLKVDLTQKGATHRGLVLQEIFSYINFLRD 387
GSL L++LG A G+ + D + + + +DLT G H +L +F YI L+
Sbjct 232 GSLFHALKILGWATGLYAGEADWSMEYSFFNVSIDLTDAGHEHMQDILGLLFEYIKVLQQ 291
Query 388 HGVGHDLVSTLAQQSHVDFHTTQPSSSLMDEAARLAHNLLTYEPYHVVAGDSLLIDADPR 447
GV + L+ +FH Q + A ++ N+ Y H + G SL +P
Sbjct 292 SGVSQWIFDELSAICEAEFH-YQAKIDPISYAVDISSNMKIYPTKHWLVGSSLPSKFNPA 350
Query 448 LTNQLL 453
+ ++L
Sbjct 351 IVQKVL 356
> cpv:cgd3_4260 peptidase'insulinase like peptidase' ; K01408
insulysin [EC:3.4.24.56]
Length=1172
Score = 164 bits (416), Expect = 5e-40, Method: Compositional matrix adjust.
Identities = 122/452 (26%), Positives = 214/452 (47%), Gaps = 13/452 (2%)
Query 9 KMRNAASVGLCVGLSAIGALAND-VLKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFA 67
K +NA+ G V + I + ++ +KP + FR+ +L N + V H + +
Sbjct 36 KSKNASFEGRYVNPNFIRIIDDEKFIKPAKSDKQFRYIKLKNELEVFLVSHNDTKVSSAN 95
Query 68 VAANTGSLYDPEDVPGLAHFLEHMLFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVF 127
+A GS +P+ PGLAH+LEH+LF+ T KYPE + ++ ++ + G NAYT++ T +
Sbjct 96 IAVKVGSYMEPDSFPGLAHYLEHLLFINTEKYPELDGFNKLISLHNGYTNAYTEDTSTSY 155
Query 128 FNKVTDSAFEEALDRFSEFFKAPLFDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLA 187
+ S+FE AL FSEFFK+PLFD Y EKE+ +I+ E + R + L+
Sbjct 156 LFSIDSSSFEAALSMFSEFFKSPLFDENYVEKELMSIENEFNFRKDSLFFRFNHVTHELS 215
Query 188 --KGPMSRFATGNSATLSTNPKAKGIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQES 245
+ RF+ GN TL T P+++GI+L D + F+ K Y + MV S +LDE
Sbjct 216 DKRSLFGRFSYGNIETLKTIPESQGINLRDEVIKFYQKEYSSNRMVLALASNHTLDELTQ 275
Query 246 LIREKLEGISAGHADWLGMVQCPGPMFD-TVKPFDHTNSGKFIHLQSFSSQPSLWVAFGL 304
+ I + L + P+ + + PF+ T + + +++ L + F +
Sbjct 276 FAYKYFSNIENKN---LPVNSIKTPIQNGNLNPFN-TMINQLVVIETLDDSRILKLIFPM 331
Query 305 PPTLTSYK-KQPTSVLTYLLEYTGEGSLAKRLRLLGLADGIS-PVVDRNTISTLLGLKVD 362
+ +K K T + L+ + GSL L+ L + ++D N T + +
Sbjct 332 KEYMVQHKNKVRTMYIDKLISFDRPGSLGHHLKSKKLILNMDFSIIDDNLGFTNAVIGFE 391
Query 363 LTQKGATHRGLVLQEIFSYINFLRDHGVGHDLVSTLAQQSHVDFHTTQPSSSLMDEAARL 422
LT G + G +L FS I F ++ ++ + F P+S+ D++ +
Sbjct 392 LTIDGEKNIGYILLSFFSVIKFASNNEFSKEIYDEWKNLIDISFKYEDPTST-SDQSEEI 450
Query 423 AHNLLTYE--PYHVVAGDSLLIDADPRLTNQL 452
+ +E P V+ D + + DP + ++
Sbjct 451 VTYYIKHECKPEDVLYSDYYMDEFDPNIYKEI 482
> cpv:cgd3_4270 peptidase'insulinase like peptidase' ; K01408
insulysin [EC:3.4.24.56]
Length=1176
Score = 152 bits (383), Expect = 3e-36, Method: Compositional matrix adjust.
Identities = 113/427 (26%), Positives = 195/427 (45%), Gaps = 12/427 (2%)
Query 33 LKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEHML 92
+KP + FR+ +L N + V H + + + GS +P+ PGLAH+LEH+L
Sbjct 65 IKPAKSDKQFRYIKLKNELEVFLVSHNDTKVSSANIVVKVGSYMEPDSFPGLAHYLEHLL 124
Query 93 FLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAPLF 152
F+ T KYPE + ++ F+ + G Y+ K + + FE AL FSEFFK+PLF
Sbjct 125 FINTEKYPEFDGFNEFVLLHNGNFETYSLRSKARYRFNIDSPFFEVALSMFSEFFKSPLF 184
Query 153 DRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLA--KGPMSRFATGNSATLSTNPKAKG 210
D Y EKE+ +ID E + R + L+ + RF+ GN TL T P+++G
Sbjct 185 DENYAEKELMSIDDEFNLCKYSKSTRFLLVMGELSDKRSFFGRFSYGNIETLKTIPESQG 244
Query 211 IDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADWLGMVQCPGP 270
I+L D + F+ K Y + MV S +LDE + I + L + P
Sbjct 245 INLRDEVIKFYQKEYSSNRMVLALASNHTLDELTQFAYKYFSNIENKN---LPVNSIKTP 301
Query 271 MFD-TVKPFDHTNSGKFIHLQSFSSQPSLWVAFGLPPTLTSY-KKQPTSVLTYLLEYTGE 328
+ + + PF+ T + + +++ L + F + + + K T + L+ +
Sbjct 302 IQNGNLNPFN-TMINQLVVIETLDDSRILKLIFPMKEYMVQHNNKARTLYIDKLISFDRP 360
Query 329 GSLAKRLRLLGLA-DGISPVVDRNTISTLLGLKVDLTQKGATHRGLVLQEIFSYINFLRD 387
GSL L+ L D ++D + T + +LT G + G +L FS I F +
Sbjct 361 GSLGHHLKSKKLILDVYFSLIDDDLGFTNAVIGFELTIDGEKNIGYILLSFFSAIKFASN 420
Query 388 HGVGHDLVSTLAQQSHVDFHTTQPSSSLMDEAARLAHNLLTYE--PYHVVAGDSLLIDAD 445
+ ++ + ++ F P+S+ D+ + + YE P V+ D + + D
Sbjct 421 NEFSKEIYDEWRKLLYISFKYEDPTSTF-DQCKEIVTYYIQYECKPEDVLYSDYYMDEFD 479
Query 446 PRLTNQL 452
P + ++
Sbjct 480 PNIYKEI 486
> tgo:TGME49_044480 insulin-degrading enzyme, putative (EC:3.4.24.56)
Length=299
Score = 141 bits (356), Expect = 4e-33, Method: Compositional matrix adjust.
Identities = 93/303 (30%), Positives = 147/303 (48%), Gaps = 25/303 (8%)
Query 31 DVLKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEH 90
D+ KP+ + R +R +L N + V P ++ A A+ N GS +DP V GLAHF EH
Sbjct 8 DIDKPKTNKRSYRFVKLPNHLSVWLVSDPAADLASAALDINVGSYFDPPPVEGLAHFCEH 67
Query 91 MLFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAP 150
MLFLGT K+P+ Y +F+ Q+GG NAYT+ T + FS FF AP
Sbjct 68 MLFLGTEKFPDETEYSNFIKQHGGCTNAYTEHTHTNY--------------HFS-FFIAP 112
Query 151 LFDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLAK--GPMSRFATGNSATLSTNPKA 208
L E+E+NA+D++ + + ND R W + LA P +RF+ GN +L PKA
Sbjct 113 LSTEIAAERELNAVDSKFRLRLVNDFIRRWQLLHKLANPDHPFNRFSCGNQVSLQEVPKA 172
Query 209 KGIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADW---LGMV 265
G D+ L FH +Y + M V + SLD + ++ + I +V
Sbjct 173 LGADVRHELLAFHKTWYSANIMTLVGLGTDSLDCLQGMVEKYFGTIKDKQVPVRPSRAIV 232
Query 266 QCPGPMFDTVKPFDHTNSGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQPTSVLTYLLEY 325
P+F H + + +++ Q + F LPP + +++ + + L++L +
Sbjct 233 DPSVPVFRR-----HEDLQQVVYIVPIKDQREIHFEFVLPPQIDAWRTKHSRCLSHLAGH 287
Query 326 TGE 328
G+
Sbjct 288 EGK 290
> cpv:cgd2_4270 secreted insulinase-like peptidase
Length=1257
Score = 132 bits (332), Expect = 3e-30, Method: Compositional matrix adjust.
Identities = 70/214 (32%), Positives = 113/214 (52%), Gaps = 3/214 (1%)
Query 43 RHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEHMLFLGTSKYPEP 102
+ Y S G+ + V E+ F+ G DP+++ GLAH +EH++FLG+ + P P
Sbjct 94 KAYTTSKGLKTLLVSDNTMLESAFSFGIGCGYYQDPDNLAGLAHLMEHVVFLGSQENPNP 153
Query 103 ESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAPLFDRKYEEKEVN 162
+D FL + GGA NAYT + T+F+ E + F++ P+ D + E++
Sbjct 154 VGWDEFLLKKGGAANAYTSADTTIFYVLSPPRELESVMSYFTKMLVNPVIDERSSVSEID 213
Query 163 AIDAEHQKNIPNDDERAWYTIRSLA--KGPMSRFATGNSATLSTNPKAKGIDLVDRLRDF 220
A++ EH+KNIPN LA + P +F TGN TL N K I+L D L+++
Sbjct 214 AVNQEHEKNIPNKVRAMIELAMYLAPEECPARKFGTGNKETLYINSKKNNINLKDALKEY 273
Query 221 HSKYYCGSNMVAVTISPRSLDEQESLIREKLEGI 254
H+ Y N V + P+S +E+ I +K++G+
Sbjct 274 HTNCYTSDNASIVIMGPQS-NEELVKIADKIDGL 306
> sce:YPR122W AXL1, FUS5, STE22; Axl1p (EC:3.4.24.-); K01422
[EC:3.4.99.-]
Length=1208
Score = 129 bits (324), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 76/229 (33%), Positives = 120/229 (52%), Gaps = 9/229 (3%)
Query 40 RDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEHMLF-LGTSK 98
R + +L NG+ A+ + P + ++ TGS DP+D+ GLAH EHM+ G+ K
Sbjct 22 RTHKVCKLPNGILALIISDPTDTSSSCSLTVCTGSHNDPKDIAGLAHLCEHMILSAGSKK 81
Query 99 YPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDS------AFEEALDRFSEFFKAPLF 152
YP+P + + + +N G+ NA+T E+T F+ ++ ++ FE LD F+ FFK PLF
Sbjct 82 YPDPGLFHTLIAKNNGSQNAFTTGEQTTFYFELPNTQNNGEFTFESILDVFASFFKEPLF 141
Query 153 DRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLAK--GPMSRFATGNSATLSTNPKAKG 210
+ KE+ AI +EH+ NI + + ++ R LA P SRF+TGN +LS+ P+ K
Sbjct 142 NPLLISKEIYAIQSEHEGNISSTTKIFYHAARILANPDHPFSRFSTGNIHSLSSIPQLKK 201
Query 211 IDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHA 259
I L L + + G N+ P+S++ L K I A
Sbjct 202 IKLKSSLNTYFENNFFGENITLCIRGPQSVNILTKLALSKFGDIKPKSA 250
> cpv:cgd3_4240 insulinase like peptidase ; K01408 insulysin [EC:3.4.24.56]
Length=1113
Score = 118 bits (296), Expect = 5e-26, Method: Compositional matrix adjust.
Identities = 103/406 (25%), Positives = 177/406 (43%), Gaps = 36/406 (8%)
Query 31 DVLKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEH 90
+ +KP+ + +L G+ + + + GS + ++ GLAHFLEH
Sbjct 21 EFIKPKESSFKCKFERLKTGLEVFLISSEKLTSTSVNLVVKVGSANEGSEIDGLAHFLEH 80
Query 91 MLFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAP 150
+FLGT K+P + F+ GGA NA TD T + + + E AL+RF EFFK+P
Sbjct 81 SVFLGTEKFPGQNEFGKFVRTYGGATNASTDILMTHYSFFIPNQFLEPALERFCEFFKSP 140
Query 151 LFDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLAKGP--MSRFATGNSATLSTNPKA 208
LF +Y + E+N ++ E N + ++ +A S+F GNS TL P+
Sbjct 141 LFSEEYLQNEINIVENEFLSKTNNFYTLLEHVLKQIADETHIYSKFFYGNSKTLKKIPEK 200
Query 209 KGIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADWLGMVQC- 267
GI L +R F +YY NMV +S S+ E L IS + + + C
Sbjct 201 NGISLRERTIRFFEEYYGSKNMVLFILSNISIQE--------LSKISYKY--FSNVRSCS 250
Query 268 ---PGP----MFDTVKPFDHTNSGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQPTSVLT 320
P P +F + + IHL +SQ L + F LP + + L+
Sbjct 251 RLSPKPESLSLFPELPYLGISKKLVKIHLNINASQ--LMLMFSLPKKEYGLSRIFSQYLS 308
Query 321 YLL-EYTGEGSLAKRLRLLGLADGISPVVDRNTISTLLGLK-----VDLTQKGATHRGLV 374
+ L +GEG L ++ + + N + LG + LT++G + +
Sbjct 309 FFLCPKSGEGLLNDIIQ-----KNLCHKISLNETYSQLGFSYITFYLFLTKEGVFNIREI 363
Query 375 LQEIFSYINFLRDHGVGHDLVSTLAQQSHVDF---HTTQPSSSLMD 417
+ +FS ++ + + + +A + +++F T PS +++
Sbjct 364 ILSLFSAFQIIKKTELIDEYIQRIANKDYLNFLKIEDTLPSIQILE 409
> cpv:cgd6_5520 peptidase'insulinase like peptidase' ; K01408
insulysin [EC:3.4.24.56]
Length=570
Score = 117 bits (292), Expect = 1e-25, Method: Compositional matrix adjust.
Identities = 78/258 (30%), Positives = 126/258 (48%), Gaps = 15/258 (5%)
Query 30 NDVLKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLE 89
N LK +R +L+N + + P + G + GS DPE +PGLAH L+
Sbjct 52 NQFLKHNYTENKYRFIKLNNELDVFLISRPGKHTYG-TLHIQVGSHNDPEYIPGLAHLLK 110
Query 90 HMLFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKA 149
LF+ T KYPE + F+ + G +A+TD E T ++ K+ + EEALDRFS+ F
Sbjct 111 QSLFINTKKYPEIYGFYKFIHLHFGETSAFTDLEYTRYYFKINSNVIEEALDRFSQSFID 170
Query 150 PLFDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLAKGPMSRFATGNSATLSTNPKAK 209
PLFD + EKE+ I+ H+ +I E ++ + + K ++ N+ T P K
Sbjct 171 PLFDEHFIEKEI--ININHENDIYKKQE--YFNLSIIRK--LTNNNNNNNETFKLEPILK 224
Query 210 GIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADWLGMVQCPG 269
ID+ + + F+ Y + M+ V S +S+DE L ++ + + Q P
Sbjct 225 EIDIRNEIIRFYQNEYSSNKMILVLTSNKSIDE--------LTNLAIKYFSKIQNKQLPL 276
Query 270 PMFDTVKPFDHTNSGKFI 287
FD F+HTN +++
Sbjct 277 KSFDEEIIFNHTNPYEYL 294
> cpv:cgd3_4170 secreted insulinase like peptidase
Length=1289
Score = 107 bits (266), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 90/417 (21%), Positives = 189/417 (45%), Gaps = 15/417 (3%)
Query 33 LKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEHML 92
+K D +R+ +L NG+ A V + ++ A+ + G LYDP + GL++ +++ L
Sbjct 59 IKSRVDKAKYRYIKLKNGLKAFLVSKEDAEKSEVAILVDVGFLYDPPKIIGLSNLVQYSL 118
Query 93 FLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAPLF 152
L + +YP + +F+ G E+ TV+ + E++ RFS +F +PL
Sbjct 119 LLASYQYPNINEFHNFIKLLNGRMYLDLHEKSTVYSFTIGTEYLSESIFRFSSYFHSPLL 178
Query 153 DRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLAKGPMSRFAT---GNSATLSTNPKAK 209
+ K + I ++ + + ++ A I G ++F T GN TL NP
Sbjct 179 NNDTINKAMLTIFSQLNR-MKRNEFWAKREIEREIIGLNAKFDTFYYGNKNTLLNNPHLS 237
Query 210 GIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADWLGMVQCPG 269
++ +++R + SK+Y +NM + LD+ E + ++ + ++ +V+
Sbjct 238 EGEIYEKVRHYFSKFYSPNNMKLAIVGREPLDKLEKYV---IQNFAHIKSNGFNIVRIDD 294
Query 270 PMFDTVKPFDHTNSGKFIHLQSFSSQ--PSLWVAFGLPPTLTSYKKQPTSVLTYLLEYTG 327
V PF S + ++ F ++ + F + + ++K+ PT + YLL+
Sbjct 295 SYKYIVNPFIRI-SKNIVTIRRFKKTGINTINLRFPIEIQVVNWKRIPTMYIKYLLDGNY 353
Query 328 EGSLAKRLRLLGLADGISP-VVDRNTISTLLGLKVDLTQKGATHRGLVLQEIFSYINFLR 386
+G L K L+ +G+++ I VV+ ST L + +DL H +++ + S + ++
Sbjct 354 KGILRKYLKSIGISNPIKVGVVNYEGFST-LDISIDLYNSQLRHSWNLVKAVISAVKYII 412
Query 387 DHGVGHDLVSTLAQQSHVDFHTTQPSSSLMDEAARLAHNLLTY--EPYHVVAGDSLL 441
+ V +V + + F+ + + D A + + Y +P ++ D ++
Sbjct 413 ELPVSERIVEEAKNVADIIFNYRETEFT-RDLAYNIVYKASKYRIKPQEIIYADEVM 468
> tgo:TGME49_006510 peptidase M16 domain containing protein (EC:4.1.1.70
3.4.24.13 3.4.24.56 3.4.21.10 3.4.24.35 3.2.1.91)
Length=2435
Score = 91.7 bits (226), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 73/233 (31%), Positives = 106/233 (45%), Gaps = 25/233 (10%)
Query 32 VLKPEADYRDFRHYQLSN-GMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEH 90
V KP D + + + + +A+ FAV+ G +DP +PG+AH LEH
Sbjct 204 VRKPPRDTSAYSVFSVPALKLEGVAIADQEEAVGSFAVSVGCGFFHDPPAIPGVAHQLEH 263
Query 91 MLFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKV-TDSAFEEALDRFSEFFKA 149
++FLG S+D F++Q GG +NA+T E T FF TD+ E F
Sbjct 264 LIFLGAEGEEAATSWDEFVSQRGGTHNAHTTAELTTFFVAAPTDTLPELLDRLLLHLFHP 323
Query 150 PLFDRKYEEKEVNAIDAEHQKNIPNDD----ERAWYTIRSLAKGPMS------------- 192
L ++ EV A+ EH+KN P+ E A SLA S
Sbjct 324 LLAAEQF-ASEVMAVQFEHEKNQPDVARVLLELAMAVTPSLASPASSATQDEVPTSFYRP 382
Query 193 ----RFATGNSATLSTNPKAKGIDLVDRLRDFHSKYYCGSNM-VAVTISPRSL 240
+F TG+ TL P +G+D++ LR+FH K Y NM +AV + RS+
Sbjct 383 EVARKFGTGDFDTLCKTPLEQGLDVLKALREFHGKCYKPENMTIAVRMGRRSV 435
Score = 40.4 bits (93), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 18/117 (15%)
Query 314 QPTSVLTYLLEYTGEGSLAKRLRLLGLADGISPVVDRNTISTLLGLKVDLTQKGATHRGL 373
QPT++L YLLEY GE +L RL+ GL V + + L +LT +G
Sbjct 639 QPTALLEYLLEYPGEAALLNRLKAQGLIADAEYVDYTTSQKAFVALLFELTDEGEEKFED 698
Query 374 VLQEIFSYINFLRDHGVGHDLVSTLAQQSHVDFHTTQPSSSLMDEAARLAHNLLTYE 430
V+ +Y LR +++ + +DF DE AR+A+ TY+
Sbjct 699 VVSATLAYAEQLR---------TSVTETYILDF---------FDEFARVANRSWTYK 737
> cpv:cgd3_4180 secreted insulinase like peptidase
Length=1215
Score = 77.8 bits (190), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 80/375 (21%), Positives = 153/375 (40%), Gaps = 16/375 (4%)
Query 33 LKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEHML 92
+K + D ++ +L N M V + + ++ GS+ DPED+PGL ++ L
Sbjct 73 IKSKIDGSTYKFMKLQNQMSVFLVSNNNFEYSIITLSVGVGSVMDPEDLPGLVSLVQESL 132
Query 93 FLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAPLF 152
LGT ++ + ++ +F+ G + E +VF KV LDR S+ + P F
Sbjct 133 CLGTYRFFDHSNFCNFIISINGEIDMEVYERNSVFTIKVGSQYISTVLDRLSDMIRNPSF 192
Query 153 DRKYEEKEVNAIDAEHQKNIPNDDERAWYTIR--SLAKGPMSRFATGNSATLSTNPKAKG 210
K + + + N + IR SL R ++ +
Sbjct 193 PEKLFFAKTKEYSGTFESLLNNSEFLFQCVIRDISLDDHIFKRLNVLTDKSIKEAREISE 252
Query 211 IDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADWLGMVQCPGP 270
I+L++++++F+ + Y S M V S ++ KL + + + P
Sbjct 253 INLLEQVKNFYYQQYSSSIMTLVVASKHTI--------AKLSNEVVLNFSLVKNLNISNP 304
Query 271 M-FDTVKPFDHTN---SGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQPTSVLTYLLEYT 326
+ FD K H + G I++++ S L + F + + P+S L YLL+
Sbjct 305 LPFDLAKIVRHPHLGVVGNAIYVKAHSIN-ELILEFPIDYQEVLWDSSPSSYLEYLLKDN 363
Query 327 GEGSLAKRLRLLGLADGISPVVDRNTIS-TLLGLKVDLTQKGATHRGLVLQEIFSYINFL 385
E SL+ L G + V + + S + ++ LT KG ++Q F + +
Sbjct 364 SEKSLSNFLIKKGWISKMDAVTNSHRYSFSSFEIRFLLTSKGIDKIKSIIQTTFIALEHI 423
Query 386 RDHGVGHDLVSTLAQ 400
+ V ++++ + Q
Sbjct 424 KSSPVNQEILAEIKQ 438
> cpv:cgd3_4210 secreted insulinase like peptidase, signal peptide
Length=1254
Score = 72.8 bits (177), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 80/387 (20%), Positives = 155/387 (40%), Gaps = 31/387 (8%)
Query 31 DVLKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEH 90
D +K D + +L N + V S + + GS +P+ PGLA L
Sbjct 86 DFIKSVKDSNKYSFIRLKNDIQVFLVSQRSSLFSSITLGVRVGSSMEPKKFPGLATLLSE 145
Query 91 MLFLGTSKYPE---PESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFF 147
+LF K P+ YD F++ N G T + + F EAL +F +
Sbjct 146 LLFYDW-KRPDVGRETPYDLFISSNSGIFKTKVAPFLTEYHLSIKHEYFSEALIKFCSYL 204
Query 148 KAPLFDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLA-KGPMSR-FATGNSATLSTN 205
K+ R + + + A+ ++ + + + ++ L+ +G ++ F GN L N
Sbjct 205 KSFSPKRIHLDPAMEALQSDFEALMGMSSIKLKQILKELSVEGHVNHGFHMGNMKRLMAN 264
Query 206 PKAKGIDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADWLGMV 265
L+ L F+ YY + M +S +S+DE LEG++ D
Sbjct 265 IDFDTEALLFELIKFYGSYYSSNLMTISIVSDKSIDE--------LEGLARTFFD----- 311
Query 266 QCPGPMFDTVKPFDHTN---------SGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQPT 316
+ P + PFD +N + K I ++S V F +P +K +P
Sbjct 312 EIPNQSKQLITPFDLSNEIIHPYIDLNNKVIQVKSAEENTYFTVIFPIPHQSPLWKYKPA 371
Query 317 SVLTYLLEYTGEGSLAKRLRLLGLADGISPV--VDRNTISTLLGLKVDLTQKGATHRGLV 374
+++ SL L+ +G+ G+ + V+ N S + ++ L KG +
Sbjct 372 EYISFFFTDYSNKSLYSYLKGIGIILGLETMIEVNDNGFSNFI-IRFKLNSKGEKAIVKI 430
Query 375 LQEIFSYINFLRDHGVGHDLVSTLAQQ 401
L+ S++ +++ + +++ + ++
Sbjct 431 LEITLSFLKLIKEVSISETIINQIRKK 457
> eco:b1494 pqqL, ECK1488, JW1489, pqqE, pqqM, yddC; predicted
peptidase; K07263 zinc protease [EC:3.4.24.-]
Length=931
Score = 71.2 bits (173), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 64/230 (27%), Positives = 109/230 (47%), Gaps = 30/230 (13%)
Query 46 QLSNGM-HAIAVH-HPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEHMLFLGTSKYPEP- 102
QL NG+ + I H HP+ ++ + +TGSL + ++ G+AHF+EHM+F GT +P
Sbjct 39 QLDNGLRYMIYPHAHPK-DQVNLWLQIHTGSLQEEDNELGVAHFVEHMMFNGTKTWPGNK 97
Query 103 --ESYDSFLTQNGGANNAYTDEEKTVF---FNKVTDSAFEEALDRFSEFFKAPLFDRKYE 157
E+++S + G NAYT ++TV+ ++ + FSE+ A F++
Sbjct 98 VIETFESMGLRFGRDVNAYTSYDETVYQVSLPTTQKQNLQQVMAIFSEWSNAATFEKLEV 157
Query 158 EKEVNAIDAEHQKNIPNDDERAWYTIRSLAKGPMSRFATGNSATLSTNPKAKGIDLVD-- 215
+ E I E + + + W T S A+ P F N+ L P I L+D
Sbjct 158 DAERGVITEEWRAH----QDAKWRT--SQARRP---FLLANTRNLDREP----IGLMDTV 204
Query 216 ------RLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHA 259
+LR F+ ++Y +NM + + E +LI++ L + A A
Sbjct 205 ATVTPAQLRQFYQRWYQPNNMTFIVVGDIDSKEALALIKDNLSKLPANKA 254
> cpv:cgd3_4280 secreted insulinase like peptidase, signal peptide
Length=1244
Score = 68.2 bits (165), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 92/438 (21%), Positives = 183/438 (41%), Gaps = 34/438 (7%)
Query 34 KPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGF-AVAANTGSLYDPEDVPGLAHFLEHML 92
KP R++R+ +LSN + V+ ++ E F ++ + G DPE++PGL+ +L + L
Sbjct 105 KPIGCTREYRYLRLSNSLKVFMVY-DKTTEISFGSMNLDFGFASDPENIPGLSRYLLYTL 163
Query 93 FLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSE-FFKAPL 151
G+ K + + ++ + A + + F + + FE AL F+ F
Sbjct 164 LFGSLKKKFTRQFALLIKKHKCSYRASISRDNSRFDFDILSNEFEIALKIFANMFINLNT 223
Query 152 FDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLAKGPMSRFATGNSATLSTNPKAKGI 211
D +EE I A+ N+ N+ + + + + S T NS+ + +
Sbjct 224 NDNIHEE-----IFAKLVNNLANNINFDSFRLSDILQEISSPTKTDNSSYDWNLLEYMQL 278
Query 212 DLVDR------LRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADWLGMV 265
+D+ LR+F ++YY M +S ++LDEQ S++R+ I G ++ + +
Sbjct 279 HHLDKFKSKRLLREFFNQYYRADRMTLTILSNKTLDEQTSIVRKYFNKIRRGDSNIITRL 338
Query 266 QCPG-----PMFDTVKPFDHTNSGKFIHLQSFSSQPSLWVAFGLPP-TLTSYKKQPTSVL 319
+ P P++D++ GK + S L + F L + +P
Sbjct 339 RLPESGIKHPLYDSI--------GKILVFNSPRRSSLLKLIFPLNNISKIKLSSKPMFFF 390
Query 320 TYLLEYTGEGSLAKRLRLLGLADGISPVVDRNTISTLLGLKVDLTQKGATHRGL--VLQE 377
+ + +GSL L + + N+I L +D+ + + ++Q
Sbjct 391 SMYISSKRKGSLYYYFYKHELVTEMKIYLS-NSIFGYYSLIIDINLQNLGELSIIHIIQG 449
Query 378 IFSYINFLRDHGVGHDLVSTLAQQSHVDFHTTQPSSSLMDEAARL--AHNLLTYEPYHVV 435
IFS +R+ +L + A+ + +S + DE + A N+L P V+
Sbjct 450 IFSVFEMMRNSKPKLELYNQ-AKTLKMKRFKHSANSFIYDECKNIQDAFNILKCPPEKVL 508
Query 436 AGDSLLIDADPRLTNQLL 453
+ S+ + + L ++L
Sbjct 509 SARSIYTEYNLELHYKIL 526
> ath:AT3G02090 MPPBETA; mitochondrial processing peptidase beta
subunit, putative; K01412 mitochondrial processing peptidase
[EC:3.4.24.64]
Length=531
Score = 67.4 bits (163), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 53/191 (27%), Positives = 87/191 (45%), Gaps = 10/191 (5%)
Query 43 RHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEHMLFLGTSKYPEP 102
R L NG+ + + A V + GS ++ ++ G AHFLEHM+F GT +
Sbjct 98 RVTTLPNGLRVATESNLSAKTATVGVWIDAGSRFESDETNGTAHFLEHMIFKGTDRR-TV 156
Query 103 ESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAPLFDRKYEEKEVN 162
+ + + GG NAYT E+T ++ KV DS +ALD ++ + F+ + +E +
Sbjct 157 RALEEEIEDIGGHLNAYTSREQTTYYAKVLDSNVNQALDVLADILQNSKFEEQRINRERD 216
Query 163 AIDAEHQKNIPNDDERAWYTIRSLA--KGPMSRFATGNSATLSTNPKAKGIDLVDRLRDF 220
I E Q+ DE + + A P+ R G + + K I D L+++
Sbjct 217 VILREMQEVEGQTDEVVLDHLHATAFQYTPLGRTILGPAQNV------KSITRED-LQNY 269
Query 221 HSKYYCGSNMV 231
+Y S MV
Sbjct 270 IKTHYTASRMV 280
> pfa:PF11_0226 petidase, M16 family
Length=2024
Score = 66.2 bits (160), Expect = 2e-10, Method: Composition-based stats.
Identities = 56/206 (27%), Positives = 94/206 (45%), Gaps = 9/206 (4%)
Query 34 KPEADYRDFRHYQL-SNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEHML 92
K E D+ ++ +++L SN + + + + S + GF+++ N G D ++PG+++ L H +
Sbjct 670 KGENDWNEYEYFKLKSNELKVLGIINKYSPKGGFSISVNCGGYDDFREIPGISNLLRHAI 729
Query 93 FLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAPLF 152
F + K + S L + NN+ E T ++ L FS+ PLF
Sbjct 730 FYKSEK--RITTLLSELGKYSSENNSRIGESFTTYYAIGKSENIYNILTLFSQNLFYPLF 787
Query 153 DRKYEEKEVNAIDAEH---QKNIPNDDERAWYTIRSLAKGPMSRFATGNSATLSTNPKAK 209
D + E EV I+ ++ + N N + I L F GN TL N
Sbjct 788 DEDFIENEVREINNKYISMENNSLNCLKIISQFITDLKYSKF--FFHGNYITLCNNVLKN 845
Query 210 GIDLVDRLRDFHSKYYCGSNMVAVTI 235
G+++ L +FH K Y NM A+TI
Sbjct 846 GLNIKKLLYNFHKKCYQPKNM-ALTI 870
> ath:AT5G42390 metalloendopeptidase
Length=1265
Score = 58.5 bits (140), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 64/223 (28%), Positives = 92/223 (41%), Gaps = 38/223 (17%)
Query 31 DVLKPEADYRDFRHY--------------QLSNGMHAIAVHH---PRSNEAGFAVAANTG 73
D+L PE D + + QL NG+ + + + P EA V + G
Sbjct 170 DLLPPEIDSAELEAFLGCELPSHPKLHRGQLKNGLRYLILPNKVPPNRFEAHMEV--HVG 227
Query 74 SLYDPEDVPGLAHFLEHMLFLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFF----- 128
S+ + ED G+AH +EH+ FLG+ K + L G +NAYTD TVF
Sbjct 228 SIDEEEDEQGIAHMIEHVAFLGSKKREK-------LLGTGARSNAYTDFHHTVFHIHSPT 280
Query 129 --NKVTDSAFEEALDRFSEFFKAPLFDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSL 186
D F LD +E P F EKE AI +E Q + N E + L
Sbjct 281 HTKDSEDDLFPSVLDALNEIAFHPKFLSSRVEKERRAILSELQ--MMNTIE--YRVDCQL 336
Query 187 AKGPMSRFATGNSATLSTNPKAKGIDLVDRLRDFHSKYYCGSN 229
+ S G + + K D VD++R FH ++Y +N
Sbjct 337 LQHLHSENKLGRRFPIGLEEQIKKWD-VDKIRKFHERWYFPAN 378
> sce:YLR163C MAS1, MIF1; Mas1p (EC:3.4.24.64); K01412 mitochondrial
processing peptidase [EC:3.4.24.64]
Length=462
Score = 57.8 bits (138), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 50/191 (26%), Positives = 81/191 (42%), Gaps = 10/191 (5%)
Query 43 RHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEHMLFLGTSKYPEP 102
R +L NG+ + P ++ A + + GS + G AHFLEH+ F GT +
Sbjct 27 RTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQ- 85
Query 103 ESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAPLFDRKYEEKEVN 162
+ + + G NAYT E TV++ K +A+D S+ + D E+E +
Sbjct 86 QGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERD 145
Query 163 AIDAEHQKNIPNDDERAWYTIRSLA--KGPMSRFATGNSATLSTNPKAKGIDLVDRLRDF 220
I E ++ DE + + + P+ R G + K I D L+D+
Sbjct 146 VIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNI------KSITRTD-LKDY 198
Query 221 HSKYYCGSNMV 231
+K Y G MV
Sbjct 199 ITKNYKGDRMV 209
> tgo:TGME49_036210 mitochondrial-processing peptidase beta subunit,
putative (EC:3.4.24.64); K01412 mitochondrial processing
peptidase [EC:3.4.24.64]
Length=524
Score = 57.4 bits (137), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 38/125 (30%), Positives = 58/125 (46%), Gaps = 3/125 (2%)
Query 47 LSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEHMLFLGTSKYPEPESYD 106
L NG+ P A V ++GS YD ++ G AHFLEHM F GT + +
Sbjct 74 LPNGIRVATQRLPFHQTATVGVWIDSGSRYDTKETNGAAHFLEHMTFKGTKRRSRIQLEQ 133
Query 107 SFLTQNGGAN-NAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAPLFDRKYEEKEVNAID 165
+N GA+ NAYT E+TV++ K + +D S+ D + + E + I
Sbjct 134 EI--ENMGAHLNAYTSREQTVYYAKAFKKDIPQCVDILSDILLNSTIDEEAVQMEKHVIL 191
Query 166 AEHQK 170
E ++
Sbjct 192 REMEE 196
> cpv:cgd3_4250 secreted insulinase like peptidase, signal peptide
Length=1198
Score = 56.2 bits (134), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 77/360 (21%), Positives = 152/360 (42%), Gaps = 14/360 (3%)
Query 33 LKPEADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEHML 92
+KP +D + F+ +L+N + I P +E ++ GS++DP ++ GL +L +++
Sbjct 74 MKPISD-QSFKLLKLNNDIEVILNSAPNVDECTASILNRVGSMHDPSNLHGLGFYLMNIM 132
Query 93 FLGTSKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAPLF 152
++ YD F N + + ++F E L SE K+P+F
Sbjct 133 LSASNSDVGSGLYD-FCIDNSLSLSYQIYSTYSLFHVTTPMVLLENVLKLVSEMLKSPVF 191
Query 153 DRKYEEKEVNAIDAEHQKNIPNDDERAWYT--IRSLAKGPMSRFATGNSATLSTNPKAKG 210
+ EK +N + E++ + N + T + S K +R G+ TL T P++K
Sbjct 192 TDEVMEKALNIL--ENKTTLDNHSYNIFSTNLVLSDPKSIFTRDRFGSRDTLKTIPQSKK 249
Query 211 IDLVDRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLEGISAGHADWLGMVQCPGP 270
ID+ L F ++ Y + ++ + + L+ + GI + +
Sbjct 250 IDVKQSLIKFFNEQYSSNRLMLSLKCNLPIQVMQDLVAKYFNGIINKNLPINTQYKSINN 309
Query 271 MFDTVKPFDHTNSGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQ-PTSVLTYLLEYTGEG 329
+ + P ++ GK ++ S+Q +L + F L L Y K P + + EG
Sbjct 310 L--IINPLSYS-VGKIMYRIDESNQ-TLMLLFPLKNYLQPYMKSGPIFFINNYICANKEG 365
Query 330 SLAKRLRLLGLADGISPVVDRNTISTL--LGLKVDLTQKGATHRGLVLQEIFSYINFLRD 387
+L + L+ ++ V N +S + +LT G + +++ F IN ++D
Sbjct 366 TLMRFLKQKNYIKNMNCHVS-NDMSGFSNIQFSFNLTNNGLFNVQNIIRAFFLSINKIKD 424
> cpv:cgd3_4200 secreted insulinase like peptidase, signal peptide
Length=1286
Score = 55.8 bits (133), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 71/352 (20%), Positives = 136/352 (38%), Gaps = 19/352 (5%)
Query 37 ADYRDFRHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEHMLFLGT 96
D +R+ +L NG+ V + + ++ GS +DP+ + G+++ + LF
Sbjct 159 GDENKYRYIKLDNGLKVFLVSNSLLYTSSLSLGIEVGSAHDPKGIDGVSYLITQELFKKE 218
Query 97 SKYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAPLFDRKY 156
+ L N G N +++ T++ + F ++ F +
Sbjct 219 QNVTSDTDFRKLLDDNNGYFNVESNKFSTIYSYNIKSKYFMSSVSAFRKRLDKTKITWSS 278
Query 157 EEKEVNAID--AEHQKNIPNDDERAWYTIRSLAKGPMSRFATGNSATLSTNPKAKGIDLV 214
++ ++ + E K + + E S + RF G + TL P + +
Sbjct 279 LDESISQVTELTEIFKRVDSLQELQLKRELSNSSHAFHRFPYGTNETLREIPSKNNLSVH 338
Query 215 DRLRDFHSKYYCGSNMVAVTISPRSLDEQESLIREKLE-----GISAGH-ADWLGMVQCP 268
+ F KYY MV + SL+ E L+R + G++ G ++ G V P
Sbjct 339 EEAIRFKKKYYSPHLMVLSIATSLSLETVEELVRNEFSDLFSTGVTPGKPEEFSGNVTHP 398
Query 269 GPMFDTVKPFDHTNSGKFIHLQSFSSQPSLWVAFGLPPTLTSYKKQPTSVLTYLLEYTGE 328
+DT+ GKFI ++S + + + + F +P +K + S + Y L
Sbjct 399 ---YDTL-------IGKFIEVKSRTPEAYITMEFPIPNQSKLWKYKLGSYVKYFLTQRFH 448
Query 329 GSLAKRLRLLGLADGIS-PVVDRNTISTLLGLKVDLTQKGATHRGLVLQEIF 379
++ LG I +V+ +T + L +K L V+Q IF
Sbjct 449 DGFLDKMTNLGWVREIEVDIVNHDTGFSNLVIKAILVDSDRDKLVRVIQAIF 500
> tpv:TP01_0151 biquinol-cytochrome C reductase complex core protein
I (EC:1.10.2.2); K01412 mitochondrial processing peptidase
[EC:3.4.24.64]
Length=518
Score = 55.1 bits (131), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 37/131 (28%), Positives = 62/131 (47%), Gaps = 2/131 (1%)
Query 47 LSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEHMLFLGTSKYPEPESYD 106
L NG+ V P S+ + V ++GS ++ + G AHFLEHM+F GT K +
Sbjct 77 LKNGLRVATVWMPGSS-STVGVWIDSGSRFETPETNGSAHFLEHMIFKGT-KSRSRHQLE 134
Query 107 SFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAPLFDRKYEEKEVNAIDA 166
+ G NAYT E+T ++ + ++ + S+ + L D + E E + I
Sbjct 135 EQIEHKGAHLNAYTSREQTAYYARCFNNDIPWCTELLSDILQNSLIDPDHMENEKHVILR 194
Query 167 EHQKNIPNDDE 177
E ++ + DE
Sbjct 195 EMEEVEKSHDE 205
> bbo:BBOV_IV001260 21.m02910; mitochondrial processing peptidase
beta subunit; K01412 mitochondrial processing peptidase
[EC:3.4.24.64]
Length=514
Score = 54.7 bits (130), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 2/124 (1%)
Query 47 LSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEHMLFLGTSKYPEPESYD 106
L NG+ +V P N V ++GS ++ ++ G AHFLEHM+F GT E +
Sbjct 71 LKNGLRVASVWMP-GNSTTVGVWIDSGSRFETKETNGAAHFLEHMIFKGTKNRSRLE-LE 128
Query 107 SFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAPLFDRKYEEKEVNAIDA 166
+ Q G NAYT E+T ++ + + + S+ + L + E E + I
Sbjct 129 EEIEQKGAHLNAYTAREQTGYYARCFNKDVPWCTELLSDILQNSLIEPSQMEAEKHVILR 188
Query 167 EHQK 170
E ++
Sbjct 189 EMEE 192
> pfa:PFI1625c organelle processing peptidase, putative; K01412
mitochondrial processing peptidase [EC:3.4.24.64]
Length=484
Score = 53.9 bits (128), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 40/136 (29%), Positives = 65/136 (47%), Gaps = 4/136 (2%)
Query 43 RHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEHMLFLGTSKYPEP 102
R +LSN + +A H + ++GS Y+ + G+AHFLEHM+F GT K
Sbjct 43 RVTELSNKL-KVATVHTNCEIPTIGLWISSGSKYENKKNNGVAHFLEHMIFKGTKKRNRI 101
Query 103 ESYDSFLTQNGGAN-NAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAPLFDRKYEEKEV 161
+ +N GA+ NAYT E+T ++ K + + ++ S+ +FD E E
Sbjct 102 QLEKEI--ENMGAHLNAYTAREQTGYYCKCFKNDIKWCIELLSDILSNSIFDDNLIELEK 159
Query 162 NAIDAEHQKNIPNDDE 177
+ I E ++ DE
Sbjct 160 HVILREMEEVEKCKDE 175
> dre:503532 pmpcb, zgc:110738; peptidase (mitochondrial processing)
beta (EC:3.4.24.64); K01412 mitochondrial processing
peptidase [EC:3.4.24.64]
Length=470
Score = 52.4 bits (124), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 46/164 (28%), Positives = 75/164 (45%), Gaps = 12/164 (7%)
Query 71 NTGSLYDPEDVPGLAHFLEHMLFLGTSKYPEPESYDSFLTQNGGAN-NAYTDEEKTVFFN 129
+ GS Y+ E G AHFLEHM F GT K + + +N GA+ NAYT E+TV++
Sbjct 72 DAGSRYENEHNNGTAHFLEHMAFKGTRKRSQLDL--ELEIENMGAHLNAYTSREQTVYYA 129
Query 130 KVTDSAFEEALDRFSEFFKAPLFDRKYEEKEVNAIDAEHQKNIPNDDERAWYTIRSLA-- 187
K A++ ++ + E+E I E Q+ N E + + + A
Sbjct 130 KAFSKDLPRAVEILADIIQNSTLGEAEIERERGVILREMQEVETNLQEVVFDYLHATAYQ 189
Query 188 KGPMSRFATGNSATLSTNPKAKGIDLVDRLRDFHSKYYCGSNMV 231
+ P+ R G + + T + DLV ++ + +Y G +V
Sbjct 190 ETPLGRTILGPTENIKTINRG---DLV----EYITTHYKGPRIV 226
> dre:393793 uqcrc1, MGC73404, zgc:73404, zgc:85750; ubiquinol-cytochrome
c reductase core protein I (EC:1.10.2.2); K00414
ubiquinol-cytochrome c reductase core subunit 1 [EC:1.10.2.2]
Length=474
Score = 52.0 bits (123), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 54/215 (25%), Positives = 90/215 (41%), Gaps = 11/215 (5%)
Query 43 RHYQLSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEHMLFLGTSKYPEP 102
R L NG+ IA + GS ++ E G FLEHM F GT K+P+
Sbjct 43 RLTTLDNGLR-IASEETNQPTCTVGLWIGCGSRFETEKNNGAGFFLEHMAFKGTKKHPQ- 100
Query 103 ESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKA-PLFDRKYEEKEV 161
+ + + GG NAYT E T ++ K +A++ +E ++ L + + E++
Sbjct 101 SALEQAVESMGGHLNAYTSREHTAYYMKTLSKDLPKAVELLAEVVQSLSLSEAEMEQQRT 160
Query 162 NAI-DAEHQKNIPNDDERAWYTIRSLAKGPMSRFATGNSATLSTNPKAKGIDLVDRLRDF 220
A+ + E + D + +S G SA + T + + L ++
Sbjct 161 VALRELEEIEGSLQDVCLDLLHATAFQGTALSHSVFGPSANIRTLTR-------NDLLEY 213
Query 221 HSKYYCGSNMVAVTISPRSLDEQESLIREKLEGIS 255
+ ++ MV T S DE SL ++ L GIS
Sbjct 214 INCHFKAPRMVLATAGGVSHDEVVSLAKQHLGGIS 248
> hsa:9512 PMPCB, Beta-MPP, MPP11, MPPB, MPPP52, P-52; peptidase
(mitochondrial processing) beta (EC:3.4.24.64); K01412 mitochondrial
processing peptidase [EC:3.4.24.64]
Length=489
Score = 51.6 bits (122), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 35/108 (32%), Positives = 51/108 (47%), Gaps = 3/108 (2%)
Query 71 NTGSLYDPEDVPGLAHFLEHMLFLGTSKYPEPESYDSFLTQNGGAN-NAYTDEEKTVFFN 129
+ GS Y+ E G AHFLEHM F GT K + + +N GA+ NAYT E+TV++
Sbjct 86 DAGSRYENEKNNGTAHFLEHMAFKGTKKRSQLDL--ELEIENMGAHLNAYTSREQTVYYA 143
Query 130 KVTDSAFEEALDRFSEFFKAPLFDRKYEEKEVNAIDAEHQKNIPNDDE 177
K A++ ++ + E+E I E Q+ N E
Sbjct 144 KAFSKDLPRAVEILADIIQNSTLGEAEIERERGVILREMQEVETNLQE 191
> mmu:73078 Pmpcb, 3110004O18Rik, MPP11, MPPB, MPPP52; peptidase
(mitochondrial processing) beta (EC:3.4.24.64); K01412 mitochondrial
processing peptidase [EC:3.4.24.64]
Length=489
Score = 51.6 bits (122), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 37/125 (29%), Positives = 58/125 (46%), Gaps = 4/125 (3%)
Query 47 LSNGMHAIAVHHPRSNEAGFAVAANTGSLYDPEDVPGLAHFLEHMLFLGTSKYPEPESYD 106
L NG+ +A + + + + GS Y+ E G AHFLEHM F GT K + +
Sbjct 63 LENGLR-VASENSGLSTCTVGLWIDAGSRYENEKNNGTAHFLEHMAFKGTKKRSQLDL-- 119
Query 107 SFLTQNGGAN-NAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAPLFDRKYEEKEVNAID 165
+N GA+ NAYT E+TV++ K A++ ++ + E+E I
Sbjct 120 ELEIENMGAHLNAYTSREQTVYYAKAFSRDLPRAVEILADIIQNSTLGEAEIERERGVIL 179
Query 166 AEHQK 170
E Q+
Sbjct 180 REMQE 184
> cpv:cgd5_3400 mitochondrial processing peptidase beta subunit
; K01412 mitochondrial processing peptidase [EC:3.4.24.64]
Length=375
Score = 51.6 bits (122), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 38/140 (27%), Positives = 65/140 (46%), Gaps = 4/140 (2%)
Query 41 DFRHYQLSNGMHAIAVHHPRS---NEAGFAVAANTGSLYDPEDVPGLAHFLEHMLFLGTS 97
D + +LSNGM + N F + ++GS + G+AHFLEH++F GT
Sbjct 40 DLKISKLSNGMRVATMKFGIDSIPNSLTFGLWVDSGSRNEDPGKNGIAHFLEHLIFKGTY 99
Query 98 KYPEPESYDSFLTQNGGANNAYTDEEKTVFFNKVTDSAFEEALDRFSEFFKAPLFDRKYE 157
E +S + G NAYT E+TV+ + + + +D S+ K F +
Sbjct 100 NRSRKE-IESQIEDLGAHLNAYTTREQTVYQIRCFNQDLPKCMDLLSDIIKNSKFCKSAI 158
Query 158 EKEVNAIDAEHQKNIPNDDE 177
E+E + E ++ +++E
Sbjct 159 EQEKGVVLREMEEVSKSEEE 178
> ath:AT5G56730 peptidase M16 family protein / insulinase family
protein
Length=956
Score = 49.7 bits (117), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 47/203 (23%), Positives = 87/203 (42%), Gaps = 24/203 (11%)
Query 46 QLSNGMHAIAVHHPRSN-----EAGFAVAANTGSLYDPEDVPGLAHFLEHMLFLGTSKYP 100
+L NG+ +++ R N A A+A GS+ + ED G+AH +EH+ F T++Y
Sbjct 44 RLDNGL----IYYVRRNSKPRMRAALALAVKVGSVLEEEDQRGVAHIVEHLAFSATTRYT 99
Query 101 EPESY---DSFLTQNGGANNAYTDEEKTVF--FNKVTD-SAFEEALDRFSEFFKAPLFDR 154
+ +S + G NA T ++T++ F V +A+ +EF +
Sbjct 100 NHDIVKFLESIGAEFGPCQNAMTTADETIYELFVPVDKPELLSQAISILAEFSSEIRVSK 159
Query 155 KYEEKEVNAIDAEHQ--KNIPNDDERAWYTIRSLAKGPMSRFATGNSATLSTNPKAKGID 212
+ EKE A+ E++ +N + + + + R G + + P A
Sbjct 160 EDLEKERGAVMEEYRGNRNATGRMQDSHWQLMMEGSKYAERLPIGLEKVIRSVPAAT--- 216
Query 213 LVDRLRDFHSKYYCGSNMVAVTI 235
++ F+ K+Y NM V +
Sbjct 217 ----VKQFYQKWYHLCNMAVVAV 235
Lambda K H
0.318 0.134 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 21227580124
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
Posted date: Sep 17, 2011 2:57 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40