bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
164,496 sequences; 82,071,388 total letters
Query= Eten_1078_orf1
Length=180
Score E
Sequences producing significant alignments: (Bits) Value
pfa:PF11_0395 guanylyl cyclase; K01769 guanylate cyclase, othe... 106 4e-23
pfa:MAL13P1.301 gc-betA; guanylyl cyclase (EC:4.6.1.2); K01769... 103 2e-22
tgo:TGME49_054370 adenylate and guanylate cyclase catalytic do... 102 8e-22
tpv:TP02_0848 guanylyl cyclase 98.6 1e-20
bbo:BBOV_I000770 16.m00775; adenylate and guanylate cyclase ca... 93.6 3e-19
cpv:cgd3_1110 P-type ATpase fused to two adenyl cyclase domain... 90.5 3e-18
dre:564719 adcy3, si:ch211-153j24.5; adenylate cyclase 3; K080... 73.9 3e-13
mmu:104111 Adcy3, AC3, mKIAA0511; adenylate cyclase 3 (EC:4.6.... 70.1 4e-12
hsa:109 ADCY3, AC3, KIAA0511; adenylate cyclase 3 (EC:4.6.1.1)... 70.1 4e-12
dre:568726 adcy7, ADCY4a; adenylate cyclase 7 (EC:4.6.1.1); K0... 64.7 2e-10
dre:557026 adcy1a, si:dkey-162m2.1; adenylate cyclase 1a (EC:4... 62.8 5e-10
dre:100333979 adenylate cyclase 1a-like 62.8 6e-10
dre:569499 adcy1b; adenylate cyclase 1b (EC:4.6.1.1); K08041 a... 62.0 1e-09
hsa:107 ADCY1, AC1; adenylate cyclase 1 (brain) (EC:4.6.1.1); ... 62.0 1e-09
mmu:432530 Adcy1, AC1, D11Bwg1392e, I-AC, KIAA4070, brl, mKIAA... 62.0 1e-09
dre:557902 adcy2b, si:dkey-266i6.1; adenylate cyclase 2b (brai... 61.6 1e-09
dre:100148976 adcy8, si:ch211-220f13.4; adenylate cyclase 8 (b... 60.1 4e-09
cel:T01C2.1 acy-4; Adenylyl CYclase family member (acy-4) 60.1 4e-09
cel:C10F3.3 acy-2; Adenylyl CYclase family member (acy-2) 59.7 5e-09
hsa:108 ADCY2, AC2, FLJ16822, FLJ45092, HBAC2, KIAA1060, MGC13... 59.3 7e-09
hsa:114 ADCY8, AC8, ADCY3, HBAC1; adenylate cyclase 8 (brain) ... 58.9 9e-09
dre:560410 adenylate cyclase 8-like; K08048 adenylate cyclase ... 58.9 9e-09
mmu:210044 Adcy2, MGC47193, mKIAA1060; adenylate cyclase 2 (EC... 58.9 1e-08
mmu:11514 Adcy8, AC8, AW060868; adenylate cyclase 8 (EC:4.6.1.... 58.9 1e-08
hsa:196883 ADCY4, AC4; adenylate cyclase 4 (EC:4.6.1.1); K0804... 57.8 2e-08
mmu:104110 Adcy4, KIAA4004, mKIAA4004; adenylate cyclase 4 (EC... 57.4 3e-08
hsa:113 ADCY7, AC7, FLJ36387, KIAA0037; adenylate cyclase 7 (E... 57.4 3e-08
dre:563724 adcy2a; adenylate cyclase 2a; K08042 adenylate cycl... 57.4 3e-08
dre:560719 si:dkey-206f10.1; K08048 adenylate cyclase 8 [EC:4.... 56.6 4e-08
mmu:11513 Adcy7, AA407758, MGC141539; adenylate cyclase 7 (EC:... 55.5 1e-07
cel:F17C8.1 acy-1; Adenylyl CYclase family member (acy-1); K08... 53.5 4e-07
dre:560807 adcy6b, si:ch211-190a18.1; adenylate cyclase 6b; K0... 53.1 5e-07
dre:562619 adcy5; adenylate cyclase 5 (EC:4.6.1.1); K08045 ade... 52.8 6e-07
dre:100332957 adenylate cyclase type 5-like 52.8 7e-07
mmu:224129 Adcy5, AW121902, Ac5; adenylate cyclase 5 (EC:4.6.1... 52.8 7e-07
hsa:111 ADCY5, AC5; adenylate cyclase 5 (EC:4.6.1.1); K08045 a... 52.8 7e-07
dre:570652 adcy6a, adcy6; adenylate cyclase 6a; K08046 adenyla... 52.4 8e-07
hsa:115 ADCY9, AC9, FLJ12046; adenylate cyclase 9 (EC:4.6.1.1)... 52.0 1e-06
mmu:11512 Adcy6, mKIAA0422; adenylate cyclase 6 (EC:4.6.1.1); ... 51.6 1e-06
hsa:112 ADCY6, AC6, DKFZp779F075, KIAA0422; adenylate cyclase ... 51.6 2e-06
mmu:11515 Adcy9, ACtp10, AW125421, D16Wsu65e, mKIAA0520; adeny... 51.2 2e-06
xla:378610 adcy9, xlAC; adenylate cyclase 9 (EC:4.6.1.1); K080... 50.8 2e-06
cel:T01A4.1 gcy-28; Guanylyl CYclase family member (gcy-28); K... 50.8 2e-06
dre:100333538 adenylyl cyclase 35C-like 50.8 3e-06
dre:568137 atrial natriuretic peptide receptor A-like 49.3 8e-06
cel:T07D1.1 gcy-31; Guanylyl CYclase family member (gcy-31) 49.3 8e-06
cel:F23H12.6 gcy-13; Guanylyl CYclase family member (gcy-13); ... 48.5 1e-05
cel:F21H7.9 gcy-20; Guanylyl CYclase family member (gcy-20); K... 48.1 2e-05
cel:F22E5.3 gcy-21; Guanylyl CYclase family member (gcy-21); K... 48.1 2e-05
cel:T03D8.5 gcy-22; Guanylyl CYclase family member (gcy-22); K... 48.1 2e-05
> pfa:PF11_0395 guanylyl cyclase; K01769 guanylate cyclase, other
[EC:4.6.1.2]
Length=4226
Score = 106 bits (264), Expect = 4e-23, Method: Composition-based stats.
Identities = 51/107 (47%), Positives = 71/107 (66%), Gaps = 7/107 (6%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M+ ++ +RE++ +P LNMRIGLH GSCVGGVIGS RLRYDLWG+DVL GN +ESNG+PG
Sbjct 4051 MIRIIKEIREKLYIPNLNMRIGLHYGSCVGGVIGSGRLRYDLWGIDVLTGNLMESNGIPG 4110
Query 63 QICCSKEFKTAFQREEQSDLRCCDQHVAFVHLKNIRVIHREVTIFTV 109
+I S+ K ++ ++ F IRVI+++V F +
Sbjct 4111 KINVSETLKNFLLQQFKN-------RFIFKPHTTIRVIYKDVKCFII 4150
Score = 36.6 bits (83), Expect = 0.051, Method: Composition-based stats.
Identities = 18/72 (25%), Positives = 41/72 (56%), Gaps = 7/72 (9%)
Query 19 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCS-------KEFK 71
+ +++G+H G + GV+GS++ +Y L+G V + +++ G P I S K+ K
Sbjct 3233 IRVKVGIHSGRIIAGVVGSKKPQYALFGDTVNTASRMKTTGKPDYIHISEATYNLVKDDK 3292
Query 72 TAFQREEQSDLR 83
T +++++++
Sbjct 3293 TLIYEKKETEIK 3304
> pfa:MAL13P1.301 gc-betA; guanylyl cyclase (EC:4.6.1.2); K01769
guanylate cyclase, other [EC:4.6.1.2]
Length=3179
Score = 103 bits (258), Expect = 2e-22, Method: Composition-based stats.
Identities = 47/108 (43%), Positives = 72/108 (66%), Gaps = 8/108 (7%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
+L ++ ++ + NMRIGLH GSCVGG+IGS R+RYD+WGLDVL+ N IESNG+PG
Sbjct 3049 ILHNINTIKIQFNKHDFNMRIGLHYGSCVGGIIGSVRIRYDMWGLDVLIANKIESNGIPG 3108
Query 63 QICCSKEFKTAF-QREEQSDLRCCDQHVAFVHLKNIRVIHREVTIFTV 109
+I CS++F+ F Q E Q+ L F + K+I + +++ ++ +
Sbjct 3109 EIICSEQFRHFFIQNEPQAKLN-------FWYYKSISINDQDIKLYVI 3149
Score = 39.3 bits (90), Expect = 0.007, Method: Composition-based stats.
Identities = 18/49 (36%), Positives = 30/49 (61%), Gaps = 0/49 (0%)
Query 19 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCS 67
++++IG+H G + GVIGS + +Y L+G V + ++S LP I S
Sbjct 1663 ISLKIGIHTGKAISGVIGSVKPQYALFGDTVNTASRMKSTSLPDHIHVS 1711
> tgo:TGME49_054370 adenylate and guanylate cyclase catalytic
domain-containing protein (EC:4.6.1.1 3.6.3.1 1.15.1.1 4.6.1.2
3.1.3.48 2.8.3.8)
Length=4368
Score = 102 bits (253), Expect = 8e-22, Method: Compositional matrix adjust.
Identities = 51/114 (44%), Positives = 69/114 (60%), Gaps = 7/114 (6%)
Query 1 RQMLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGL 60
+ M+ ++ VRE + +P LNMRIGLH GSCVGGVIGS RLRYDLWG+DVL GN +ESNG+
Sbjct 4105 KAMIGNITEVRERLCIPNLNMRIGLHYGSCVGGVIGSGRLRYDLWGMDVLTGNMMESNGV 4164
Query 61 PGQICCSKEFKTAFQREEQSDLRCCDQHVAFVHLKNIRVIHREVTIFTVHSAFD 114
PG+I S+ K ++ + F K + V+ V + + A D
Sbjct 4165 PGKINVSEILKNEMEKGFPGEF-------VFKFNKTVAVLQSTVDSYLIRPAKD 4211
Score = 40.0 bits (92), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 16/51 (31%), Positives = 33/51 (64%), Gaps = 0/51 (0%)
Query 19 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKE 69
+ ++IG+H G + GV+G+++ +Y L+G V + +++ G PG I S++
Sbjct 3115 IRVKIGIHSGRVISGVVGAKKPQYALFGDTVNTASRMKTTGQPGYIHISED 3165
> tpv:TP02_0848 guanylyl cyclase
Length=2664
Score = 98.6 bits (244), Expect = 1e-20, Method: Composition-based stats.
Identities = 45/109 (41%), Positives = 66/109 (60%), Gaps = 7/109 (6%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M+ ++ + +P L MRIGLH GSC+GGVIGS RLRYD+WG DV N IESNG+PG
Sbjct 2541 MIHIIDETSKIFSIPDLKMRIGLHYGSCIGGVIGSGRLRYDVWGTDVYTANMIESNGVPG 2600
Query 63 QICCSKEFKTAFQREEQSDLRCCDQHVAFVHLKNIRVIHREVTIFTVHS 111
++C S++F+ R + + F H K+I +I + V + + +
Sbjct 2601 EVCVSEKFRDIITRHFPNRFK-------FEHHKDINIIDKTVKSYIIRN 2642
Score = 30.4 bits (67), Expect = 3.1, Method: Composition-based stats.
Identities = 14/50 (28%), Positives = 31/50 (62%), Gaps = 0/50 (0%)
Query 19 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSK 68
+ ++IG++ G + G++GS++ +Y L+G V + ++ G G+I S+
Sbjct 1840 IGVKIGINSGYVISGLVGSKKPQYALFGDTVNTASRMKMTGEVGRIHISE 1889
> bbo:BBOV_I000770 16.m00775; adenylate and guanylate cyclase
catalytic domain containing protein
Length=2446
Score = 93.6 bits (231), Expect = 3e-19, Method: Composition-based stats.
Identities = 46/97 (47%), Positives = 60/97 (61%), Gaps = 8/97 (8%)
Query 1 RQMLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGL 60
+ M+ + VRE +PGLNMRIGLH G VGGVIGS RLRYDLWG+D+ N +ES+G+
Sbjct 2335 QSMIRTIRDVRESFDIPGLNMRIGLHYGHAVGGVIGSGRLRYDLWGMDIHTANAMESHGI 2394
Query 61 PGQICCSKE--------FKTAFQREEQSDLRCCDQHV 89
PG+I S+ F F E SD++ D+ V
Sbjct 2395 PGKINISERLKLILMTNFPERFTFEFHSDVQVIDRCV 2431
> cpv:cgd3_1110 P-type ATpase fused to two adenyl cyclase domains
and 21 predicted transmembrane regions
Length=3848
Score = 90.5 bits (223), Expect = 3e-18, Method: Composition-based stats.
Identities = 37/74 (50%), Positives = 52/74 (70%), Gaps = 0/74 (0%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
MLE + VRE++ +P L+MRIGLH G C+GG++GS RLRY++WG DV++GN +ES G PG
Sbjct 3712 MLEKIAFVREKLSLPELSMRIGLHYGGCIGGIVGSSRLRYEVWGHDVIIGNRMESCGTPG 3771
Query 63 QICCSKEFKTAFQR 76
I S + +
Sbjct 3772 NITISGQLHEVLSK 3785
Score = 38.1 bits (87), Expect = 0.015, Method: Composition-based stats.
Identities = 18/56 (32%), Positives = 34/56 (60%), Gaps = 0/56 (0%)
Query 12 EEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCS 67
+EM + L ++IG+H G + GV+G+ + +Y L+G V + ++S+ G+I S
Sbjct 2858 QEMALKQLKLKIGIHSGRVISGVVGTNKPQYALFGDTVNTASRMKSSCETGKIQVS 2913
> dre:564719 adcy3, si:ch211-153j24.5; adenylate cyclase 3; K08043
adenylate cyclase 3 [EC:4.6.1.1]
Length=1071
Score = 73.9 bits (180), Expect = 3e-13, Method: Composition-based stats.
Identities = 35/88 (39%), Positives = 56/88 (63%), Gaps = 5/88 (5%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M+E + VRE+ Q G++MR+G+H G+ +GGV+G +R ++D+W DV V N +ES G+PG
Sbjct 382 MVEAISYVREKTQT-GVDMRVGVHSGTVLGGVLGQKRWQFDVWSTDVTVANKMESGGIPG 440
Query 63 QICCSKEFKTA----FQREEQSDLRCCD 86
++ S+ K F+ EE + CD
Sbjct 441 RVHISQSTKDCLHDEFELEEGNGGERCD 468
Score = 47.4 bits (111), Expect = 3e-05, Method: Composition-based stats.
Identities = 21/44 (47%), Positives = 31/44 (70%), Gaps = 0/44 (0%)
Query 21 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQI 64
+RIGL+ GS + GVIG+R+ +D+WG V V + +ES G+ G I
Sbjct 970 LRIGLNKGSVLAGVIGARKPHFDIWGNTVNVASRMESTGVMGNI 1013
> mmu:104111 Adcy3, AC3, mKIAA0511; adenylate cyclase 3 (EC:4.6.1.1);
K08043 adenylate cyclase 3 [EC:4.6.1.1]
Length=1144
Score = 70.1 bits (170), Expect = 4e-12, Method: Composition-based stats.
Identities = 28/66 (42%), Positives = 48/66 (72%), Gaps = 1/66 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M+E + VRE+ + G++MR+G+H G+ +GGV+G +R +YD+W DV V N +E+ G+PG
Sbjct 394 MVEAISYVREKTKT-GVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPG 452
Query 63 QICCSK 68
++ S+
Sbjct 453 RVHISQ 458
Score = 46.6 bits (109), Expect = 5e-05, Method: Composition-based stats.
Identities = 21/49 (42%), Positives = 32/49 (65%), Gaps = 0/49 (0%)
Query 21 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKE 69
+RIG++ G + GVIG+R+ YD+WG V V + +ES G+ G I +E
Sbjct 1040 LRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMGNIQVVEE 1088
> hsa:109 ADCY3, AC3, KIAA0511; adenylate cyclase 3 (EC:4.6.1.1);
K08043 adenylate cyclase 3 [EC:4.6.1.1]
Length=1144
Score = 70.1 bits (170), Expect = 4e-12, Method: Composition-based stats.
Identities = 28/66 (42%), Positives = 48/66 (72%), Gaps = 1/66 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M+E + VRE+ + G++MR+G+H G+ +GGV+G +R +YD+W DV V N +E+ G+PG
Sbjct 394 MVEAISYVREKTKT-GVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPG 452
Query 63 QICCSK 68
++ S+
Sbjct 453 RVHISQ 458
Score = 46.6 bits (109), Expect = 5e-05, Method: Composition-based stats.
Identities = 21/49 (42%), Positives = 32/49 (65%), Gaps = 0/49 (0%)
Query 21 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKE 69
+RIG++ G + GVIG+R+ YD+WG V V + +ES G+ G I +E
Sbjct 1040 LRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMGNIQVVEE 1088
> dre:568726 adcy7, ADCY4a; adenylate cyclase 7 (EC:4.6.1.1);
K08047 adenylate cyclase 7 [EC:4.6.1.1]
Length=1043
Score = 64.7 bits (156), Expect = 2e-10, Method: Composition-based stats.
Identities = 38/103 (36%), Positives = 61/103 (59%), Gaps = 8/103 (7%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M E ++ VRE V +NMR+G+H G+ + GVIG R+ ++D+W DV + N +ES GLPG
Sbjct 356 MCEAIKQVREATGV-DINMRVGVHSGNVLCGVIGLRKWQFDVWSHDVTLANHMESGGLPG 414
Query 63 QICCS----KEFKTAFQREE-QSDLRCCDQHVAFVHLKNIRVI 100
++ + K A++ EE LR D ++ +++K VI
Sbjct 415 RVHITEATLKHLNKAYEVEEGNGHLR--DTYLKELNIKTFLVI 455
Score = 47.4 bits (111), Expect = 2e-05, Method: Composition-based stats.
Identities = 21/55 (38%), Positives = 35/55 (63%), Gaps = 0/55 (0%)
Query 21 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKEFKTAFQ 75
+R+G++ G + GVIG+R+ +YD+WG V V + +ES G G+I ++E Q
Sbjct 951 LRVGINHGPVIAGVIGARKPQYDIWGNTVNVASRMESTGELGKIQVTEETSIVLQ 1005
> dre:557026 adcy1a, si:dkey-162m2.1; adenylate cyclase 1a (EC:4.6.1.1);
K08041 adenylate cyclase 1 [EC:4.6.1.1]
Length=1114
Score = 62.8 bits (151), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 28/66 (42%), Positives = 45/66 (68%), Gaps = 1/66 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M++ + +V E +V LNMR+GLH G + GV+G R+ +YD+W DV + N +E+ GLPG
Sbjct 371 MIDTITSVAEATEV-DLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANMMEAGGLPG 429
Query 63 QICCSK 68
++ +K
Sbjct 430 KVHITK 435
Score = 49.7 bits (117), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 21/49 (42%), Positives = 36/49 (73%), Gaps = 0/49 (0%)
Query 21 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKE 69
+R+G++VG V GVIG+RR +YD+WG V V + ++S G+ G+I +++
Sbjct 968 LRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGKIQVTED 1016
> dre:100333979 adenylate cyclase 1a-like
Length=829
Score = 62.8 bits (151), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 28/66 (42%), Positives = 45/66 (68%), Gaps = 1/66 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M++ + +V E +V LNMR+GLH G + GV+G R+ +YD+W DV + N +E+ GLPG
Sbjct 118 MIDTITSVAEATEVD-LNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANMMEAGGLPG 176
Query 63 QICCSK 68
++ +K
Sbjct 177 KVHITK 182
Score = 49.7 bits (117), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 21/49 (42%), Positives = 36/49 (73%), Gaps = 0/49 (0%)
Query 21 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKE 69
+R+G++VG V GVIG+RR +YD+WG V V + ++S G+ G+I +++
Sbjct 683 LRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGKIQVTED 731
> dre:569499 adcy1b; adenylate cyclase 1b (EC:4.6.1.1); K08041
adenylate cyclase 1 [EC:4.6.1.1]
Length=1114
Score = 62.0 bits (149), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 27/62 (43%), Positives = 43/62 (69%), Gaps = 1/62 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M++ + +V E +V LNMR+GLH G + GV+G R+ +YD+W DV + N +E+ GLPG
Sbjct 356 MIDTITSVAEATEV-DLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANMMEAGGLPG 414
Query 63 QI 64
++
Sbjct 415 KV 416
Score = 54.7 bits (130), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 26/64 (40%), Positives = 41/64 (64%), Gaps = 2/64 (3%)
Query 21 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKEFKTAFQREEQS 80
+R+G++VG V GVIG+RR +YD+WG V V + ++S G+PG+I +++ Q
Sbjct 955 LRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVPGKIQVTEDVYRLLQ--NNY 1012
Query 81 DLRC 84
DL C
Sbjct 1013 DLMC 1016
> hsa:107 ADCY1, AC1; adenylate cyclase 1 (brain) (EC:4.6.1.1);
K08041 adenylate cyclase 1 [EC:4.6.1.1]
Length=1119
Score = 62.0 bits (149), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 28/66 (42%), Positives = 45/66 (68%), Gaps = 1/66 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M++ + +V E +V LNMR+GLH G + GV+G R+ +YD+W DV + N +E+ GLPG
Sbjct 378 MIDTITSVAEATEV-DLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPG 436
Query 63 QICCSK 68
++ +K
Sbjct 437 KVHITK 442
Score = 50.4 bits (119), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 23/56 (41%), Positives = 38/56 (67%), Gaps = 0/56 (0%)
Query 21 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKEFKTAFQR 76
+R+G++VG V GVIG+RR +YD+WG V V + ++S G+ G+I ++E +R
Sbjct 975 LRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLRR 1030
> mmu:432530 Adcy1, AC1, D11Bwg1392e, I-AC, KIAA4070, brl, mKIAA4070;
adenylate cyclase 1 (EC:4.6.1.1); K08041 adenylate cyclase
1 [EC:4.6.1.1]
Length=1118
Score = 62.0 bits (149), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 28/66 (42%), Positives = 45/66 (68%), Gaps = 1/66 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M++ + +V E +V LNMR+GLH G + GV+G R+ +YD+W DV + N +E+ GLPG
Sbjct 377 MIDTITSVAEATEV-DLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPG 435
Query 63 QICCSK 68
++ +K
Sbjct 436 KVHITK 441
Score = 50.8 bits (120), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 23/56 (41%), Positives = 38/56 (67%), Gaps = 0/56 (0%)
Query 21 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKEFKTAFQR 76
+R+G++VG V GVIG+RR +YD+WG V V + ++S G+ G+I ++E +R
Sbjct 974 LRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLKR 1029
> dre:557902 adcy2b, si:dkey-266i6.1; adenylate cyclase 2b (brain)
(EC:4.6.1.1); K08042 adenylate cyclase 2 [EC:4.6.1.1]
Length=1139
Score = 61.6 bits (148), Expect = 1e-09, Method: Composition-based stats.
Identities = 27/62 (43%), Positives = 43/62 (69%), Gaps = 1/62 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M E +E VRE V +NMR+G+H G+ + GVIG ++ +YD+W DV + N +E+ G+PG
Sbjct 412 MCEAIEKVREATGV-DINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPG 470
Query 63 QI 64
++
Sbjct 471 RV 472
Score = 47.8 bits (112), Expect = 2e-05, Method: Composition-based stats.
Identities = 20/49 (40%), Positives = 35/49 (71%), Gaps = 0/49 (0%)
Query 21 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKE 69
MR+G++ G + GVIG+++ +YD+WG V V + +ES G+ G+I ++E
Sbjct 1045 MRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMESTGVLGKIQVTEE 1093
> dre:100148976 adcy8, si:ch211-220f13.4; adenylate cyclase 8
(brain) (EC:4.6.1.1); K08048 adenylate cyclase 8 [EC:4.6.1.1]
Length=1225
Score = 60.1 bits (144), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 27/66 (40%), Positives = 44/66 (66%), Gaps = 1/66 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M++ + VR + ++MRIG+H GS + GV+G R+ ++D+W DV + N +ES G+PG
Sbjct 463 MIKTIRYVRSRTK-HDIDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPG 521
Query 63 QICCSK 68
+I SK
Sbjct 522 RIHISK 527
Score = 47.4 bits (111), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 20/51 (39%), Positives = 34/51 (66%), Gaps = 0/51 (0%)
Query 19 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKE 69
+RIG+ GS V GVIG+++ +YD+WG V + + ++S G+ G+I +E
Sbjct 1060 FQLRIGMAHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGKIQLPEE 1110
> cel:T01C2.1 acy-4; Adenylyl CYclase family member (acy-4)
Length=1013
Score = 60.1 bits (144), Expect = 4e-09, Method: Composition-based stats.
Identities = 26/64 (40%), Positives = 42/64 (65%), Gaps = 1/64 (1%)
Query 1 RQMLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGL 60
R M+E + VRE M + +NMR+G+H G GV+G ++ ++D+W DV + N +ES GL
Sbjct 375 RDMIEAIRLVRE-MTLVNVNMRVGIHTGKAHCGVLGLKKWQFDVWSNDVTLANQMESGGL 433
Query 61 PGQI 64
G++
Sbjct 434 AGRV 437
Score = 54.3 bits (129), Expect = 2e-07, Method: Composition-based stats.
Identities = 24/57 (42%), Positives = 38/57 (66%), Gaps = 0/57 (0%)
Query 19 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKEFKTAFQ 75
N+RIG++VG V GVIGS + YD+WG V V + ++S G+ G+I ++E K+ +
Sbjct 920 FNLRIGINVGPVVAGVIGSDKPHYDIWGNSVNVASRMDSGGVAGRIQVTEEVKSILE 976
> cel:C10F3.3 acy-2; Adenylyl CYclase family member (acy-2)
Length=1080
Score = 59.7 bits (143), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 27/70 (38%), Positives = 45/70 (64%), Gaps = 1/70 (1%)
Query 2 QMLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLP 61
+M+ ++ VR V +NMRIG+H GS + G++G R+ ++D+W DV + N +ES G+P
Sbjct 388 EMINTIKQVRIATGV-DVNMRIGVHTGSVLCGIMGLRKWQFDIWSDDVTLANHMESAGVP 446
Query 62 GQICCSKEFK 71
G + +K K
Sbjct 447 GAVHITKSTK 456
Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 19/58 (32%), Positives = 35/58 (60%), Gaps = 0/58 (0%)
Query 18 GLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKEFKTAFQ 75
+RIG+ VG V GVIG+++ +YD+WG V + + ++++G P +I + + Q
Sbjct 970 NFELRIGMSVGPLVAGVIGAQKPQYDIWGNTVNLASRMDTHGEPRKIHATTDMGRVLQ 1027
> hsa:108 ADCY2, AC2, FLJ16822, FLJ45092, HBAC2, KIAA1060, MGC133314;
adenylate cyclase 2 (brain) (EC:4.6.1.1); K08042 adenylate
cyclase 2 [EC:4.6.1.1]
Length=1091
Score = 59.3 bits (142), Expect = 7e-09, Method: Composition-based stats.
Identities = 31/86 (36%), Positives = 53/86 (61%), Gaps = 6/86 (6%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M E ++ VR+ V +NMR+G+H G+ + GVIG ++ +YD+W DV + N +E+ G+PG
Sbjct 365 MCEAIKKVRDATGV-DINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPG 423
Query 63 QICCS----KEFKTAFQREE-QSDLR 83
++ S + A++ EE D+R
Sbjct 424 RVHISSVTLEHLNGAYKVEEGDGDIR 449
Score = 42.7 bits (99), Expect = 6e-04, Method: Composition-based stats.
Identities = 18/57 (31%), Positives = 35/57 (61%), Gaps = 0/57 (0%)
Query 19 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKEFKTAFQ 75
+R+G++ G + GVIG+++ +YD+WG V V + ++S G+ +I ++E Q
Sbjct 995 FKLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSLVLQ 1051
> hsa:114 ADCY8, AC8, ADCY3, HBAC1; adenylate cyclase 8 (brain)
(EC:4.6.1.1); K08048 adenylate cyclase 8 [EC:4.6.1.1]
Length=1251
Score = 58.9 bits (141), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 27/66 (40%), Positives = 44/66 (66%), Gaps = 1/66 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M++ + VR + ++MRIG+H GS + GV+G R+ ++D+W DV + N +ES G+PG
Sbjct 489 MIKTIRYVRSRTK-HDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPG 547
Query 63 QICCSK 68
+I SK
Sbjct 548 RIHISK 553
Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 28/81 (34%), Positives = 44/81 (54%), Gaps = 10/81 (12%)
Query 19 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKEFKTAFQREE 78
+RIG+ GS V GVIG+++ +YD+WG V + + ++S G+ G+I Q E
Sbjct 1085 FELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRI----------QVPE 1134
Query 79 QSDLRCCDQHVAFVHLKNIRV 99
++ L DQ AF + I V
Sbjct 1135 ETYLILKDQGFAFDYRGEIYV 1155
> dre:560410 adenylate cyclase 8-like; K08048 adenylate cyclase
8 [EC:4.6.1.1]
Length=1183
Score = 58.9 bits (141), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 26/66 (39%), Positives = 46/66 (69%), Gaps = 1/66 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M+ + VR+E++ ++MRIG+H GS + GV+G ++ ++D+W DV V N +E+ G+PG
Sbjct 461 MINTIRYVRKELK-RDMDMRIGIHSGSVLCGVLGLQKWQFDVWSWDVDVANMLEAGGIPG 519
Query 63 QICCSK 68
+I S+
Sbjct 520 RIHISR 525
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 18/44 (40%), Positives = 31/44 (70%), Gaps = 0/44 (0%)
Query 21 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQI 64
+R+G+ G V GVIG+ + +YD+WG+ V + + ++S GL G+I
Sbjct 1046 LRVGISHGPVVAGVIGATKPQYDIWGMTVNLASRMDSTGLSGRI 1089
> mmu:210044 Adcy2, MGC47193, mKIAA1060; adenylate cyclase 2 (EC:4.6.1.1);
K08042 adenylate cyclase 2 [EC:4.6.1.1]
Length=1095
Score = 58.9 bits (141), Expect = 1e-08, Method: Composition-based stats.
Identities = 29/80 (36%), Positives = 50/80 (62%), Gaps = 5/80 (6%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M E ++ VR+ V +NMR+G+H G+ + GVIG ++ +YD+W DV + N +E+ G+PG
Sbjct 369 MCEAIKKVRDATGV-DINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPG 427
Query 63 QICCS----KEFKTAFQREE 78
++ S + A++ EE
Sbjct 428 RVHISSVTLEHLNGAYKVEE 447
Score = 42.4 bits (98), Expect = 9e-04, Method: Composition-based stats.
Identities = 18/57 (31%), Positives = 35/57 (61%), Gaps = 0/57 (0%)
Query 19 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKEFKTAFQ 75
+R+G++ G + GVIG+++ +YD+WG V V + ++S G+ +I ++E Q
Sbjct 999 FKLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSLILQ 1055
> mmu:11514 Adcy8, AC8, AW060868; adenylate cyclase 8 (EC:4.6.1.1);
K08048 adenylate cyclase 8 [EC:4.6.1.1]
Length=1249
Score = 58.9 bits (141), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 24/50 (48%), Positives = 37/50 (74%), Gaps = 0/50 (0%)
Query 19 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSK 68
++MRIG+H GS + GV+G R+ ++D+W DV + N +ES G+PG+I SK
Sbjct 502 VDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISK 551
Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 28/81 (34%), Positives = 44/81 (54%), Gaps = 10/81 (12%)
Query 19 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKEFKTAFQREE 78
+RIG+ GS V GVIG+++ +YD+WG V + + ++S G+ G+I Q E
Sbjct 1083 FELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRI----------QVPE 1132
Query 79 QSDLRCCDQHVAFVHLKNIRV 99
++ L DQ AF + I V
Sbjct 1133 ETYLILKDQGFAFDYRGEIYV 1153
> hsa:196883 ADCY4, AC4; adenylate cyclase 4 (EC:4.6.1.1); K08044
adenylate cyclase 4 [EC:4.6.1.1]
Length=1077
Score = 57.8 bits (138), Expect = 2e-08, Method: Composition-based stats.
Identities = 26/66 (39%), Positives = 43/66 (65%), Gaps = 2/66 (3%)
Query 1 RQMLEHVEAVREEMQVPG--LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESN 58
R L+ A+R+ G +NMR+G+H GS + GVIG ++ +YD+W DV + N +E+
Sbjct 343 RMGLDMCRAIRKLRAATGVDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAG 402
Query 59 GLPGQI 64
G+PG++
Sbjct 403 GVPGRV 408
Score = 49.3 bits (116), Expect = 8e-06, Method: Composition-based stats.
Identities = 23/55 (41%), Positives = 37/55 (67%), Gaps = 0/55 (0%)
Query 21 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKEFKTAFQ 75
+R+GL+ G V GVIG+++ +YD+WG V V + +ES G+ G+I ++E A Q
Sbjct 983 LRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLGKIQVTEETAWALQ 1037
> mmu:104110 Adcy4, KIAA4004, mKIAA4004; adenylate cyclase 4 (EC:4.6.1.1);
K08044 adenylate cyclase 4 [EC:4.6.1.1]
Length=1077
Score = 57.4 bits (137), Expect = 3e-08, Method: Composition-based stats.
Identities = 26/66 (39%), Positives = 43/66 (65%), Gaps = 2/66 (3%)
Query 1 RQMLEHVEAVREEMQVPG--LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESN 58
R L+ A+R+ G +NMR+G+H GS + GVIG ++ +YD+W DV + N +E+
Sbjct 343 RMGLDMCRAIRKLRVATGVDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAG 402
Query 59 GLPGQI 64
G+PG++
Sbjct 403 GVPGRV 408
Score = 49.7 bits (117), Expect = 5e-06, Method: Composition-based stats.
Identities = 23/55 (41%), Positives = 37/55 (67%), Gaps = 0/55 (0%)
Query 21 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKEFKTAFQ 75
+R+GL+ G V GVIG+++ +YD+WG V V + +ES G+ G+I ++E A Q
Sbjct 985 LRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLGKIQVTEETARALQ 1039
> hsa:113 ADCY7, AC7, FLJ36387, KIAA0037; adenylate cyclase 7
(EC:4.6.1.1); K08047 adenylate cyclase 7 [EC:4.6.1.1]
Length=1080
Score = 57.4 bits (137), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 26/62 (41%), Positives = 43/62 (69%), Gaps = 1/62 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M + ++ VRE V +NMR+G+H G+ + GVIG R+ +YD+W DV + N +E+ G+PG
Sbjct 354 MCQAIKQVREATGVD-INMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPG 412
Query 63 QI 64
++
Sbjct 413 RV 414
Score = 46.2 bits (108), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 22/55 (40%), Positives = 36/55 (65%), Gaps = 0/55 (0%)
Query 21 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKEFKTAFQ 75
+R+G++ G + GVIG+R+ +YD+WG V V + +ES G G+I ++E T Q
Sbjct 988 LRVGINHGPVIAGVIGARKPQYDIWGNTVNVASRMESTGELGKIQVTEETCTILQ 1042
> dre:563724 adcy2a; adenylate cyclase 2a; K08042 adenylate cyclase
2 [EC:4.6.1.1]
Length=960
Score = 57.4 bits (137), Expect = 3e-08, Method: Composition-based stats.
Identities = 25/67 (37%), Positives = 45/67 (67%), Gaps = 1/67 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M E ++ VR+ V ++MR+G+H G+ + GVIG ++ +YD+W DV + N +E+ G+PG
Sbjct 229 MCEAIKKVRDATGVE-ISMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPG 287
Query 63 QICCSKE 69
++ + E
Sbjct 288 RVHITSE 294
Score = 43.1 bits (100), Expect = 4e-04, Method: Composition-based stats.
Identities = 19/57 (33%), Positives = 35/57 (61%), Gaps = 0/57 (0%)
Query 19 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKEFKTAFQ 75
+R+G++ G GVIG+++ +YD+WG V V + ++S G+ G+I ++E Q
Sbjct 864 FKLRVGINHGPVKAGVIGAQKPQYDIWGNTVNVASRMDSTGVLGKIQVTEETSCILQ 920
> dre:560719 si:dkey-206f10.1; K08048 adenylate cyclase 8 [EC:4.6.1.1]
Length=1199
Score = 56.6 bits (135), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 27/80 (33%), Positives = 51/80 (63%), Gaps = 5/80 (6%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M+ + ++R++ Q ++MRIG+H GS + GV+G ++ ++D+W DV + N +E+ G+PG
Sbjct 466 MISTMRSLRKQ-QNFDMDMRIGIHTGSVLCGVLGLQKWQFDVWSWDVGIANMLEAGGIPG 524
Query 63 QICCSKE----FKTAFQREE 78
+I S+ +FQ E+
Sbjct 525 RIHISRATLDCLDGSFQTED 544
Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 20/59 (33%), Positives = 37/59 (62%), Gaps = 2/59 (3%)
Query 8 EAVRE--EMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQI 64
E +RE + + +R+G+ G V GVIG+ + +YD+WG+ V + + ++S G+ G+I
Sbjct 1040 ETLREINKHSMNNFQLRVGIAHGPVVAGVIGATKPQYDIWGMTVNLASRMDSTGVSGRI 1098
> mmu:11513 Adcy7, AA407758, MGC141539; adenylate cyclase 7 (EC:4.6.1.1);
K08047 adenylate cyclase 7 [EC:4.6.1.1]
Length=1099
Score = 55.5 bits (132), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 25/60 (41%), Positives = 42/60 (70%), Gaps = 1/60 (1%)
Query 5 EHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQI 64
E ++ VRE V ++MR+G+H G+ + GVIG R+ +YD+W DV + N +E+ G+PG++
Sbjct 358 EAIKQVREATGV-DISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRV 416
Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 22/55 (40%), Positives = 36/55 (65%), Gaps = 0/55 (0%)
Query 21 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKEFKTAFQ 75
+R+G++ G + GVIG+R+ +YD+WG V V + +ES G G+I ++E T Q
Sbjct 1007 LRVGINHGPVIAGVIGARKPQYDIWGNTVNVASRMESTGELGKIQVTEETCTILQ 1061
> cel:F17C8.1 acy-1; Adenylyl CYclase family member (acy-1); K08049
adenylate cyclase 9 [EC:4.6.1.1]
Length=1253
Score = 53.5 bits (127), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 22/67 (32%), Positives = 44/67 (65%), Gaps = 4/67 (5%)
Query 19 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQI----CCSKEFKTAF 74
+NMR+G+H G + G++G++R ++D++ DV + N++ES+G+ G++ +K K +
Sbjct 409 VNMRVGIHTGKVMCGMVGTKRFKFDVFSNDVTLANEMESSGVAGRVHVSEATAKLLKGLY 468
Query 75 QREEQSD 81
+ EE D
Sbjct 469 EIEEGPD 475
Score = 42.4 bits (98), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 22/74 (29%), Positives = 41/74 (55%), Gaps = 7/74 (9%)
Query 2 QMLEHVEAVREEMQVPGLNM-------RIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGND 54
QM++ AV+ + V ++ ++GL++G GVIG+ +L YD+WG V + +
Sbjct 1128 QMVDFALAVQHVLSVFNEDLLNFDFVCKLGLNIGPVTAGVIGTTKLYYDIWGDTVNIASR 1187
Query 55 IESNGLPGQICCSK 68
+ S G+ +I S+
Sbjct 1188 MYSTGVLNRIQVSQ 1201
> dre:560807 adcy6b, si:ch211-190a18.1; adenylate cyclase 6b;
K08046 adenylate cyclase 6 [EC:4.6.1.1]
Length=1123
Score = 53.1 bits (126), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 26/66 (39%), Positives = 41/66 (62%), Gaps = 1/66 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M+E + VRE V +NMR+G+H G GV+G R+ ++D+W DV + N +E+ G G
Sbjct 462 MIEAISLVREVTGV-NVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANQMEAGGKAG 520
Query 63 QICCSK 68
+I +K
Sbjct 521 RIHITK 526
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 24/68 (35%), Positives = 42/68 (61%), Gaps = 6/68 (8%)
Query 3 MLEHVEAVREEMQ------VPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIE 56
+ ++ +RE+M+ M+IGL++G V GVIG+R+ +YD+WG V V + ++
Sbjct 1013 LADYAMRLREQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMD 1072
Query 57 SNGLPGQI 64
S G+P +I
Sbjct 1073 STGVPDRI 1080
> dre:562619 adcy5; adenylate cyclase 5 (EC:4.6.1.1); K08045 adenylate
cyclase 5 [EC:4.6.1.1]
Length=1186
Score = 52.8 bits (125), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 26/66 (39%), Positives = 41/66 (62%), Gaps = 1/66 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M+E + VRE V +NMR+G+H G GV+G R+ ++D+W DV + N +E+ G G
Sbjct 474 MIEAISLVREVTGV-NVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAG 532
Query 63 QICCSK 68
+I +K
Sbjct 533 RIHITK 538
Score = 49.7 bits (117), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 22/52 (42%), Positives = 34/52 (65%), Gaps = 0/52 (0%)
Query 13 EMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQI 64
E M+IGL++G V GVIG+R+ +YD+WG V V + ++S G+P +I
Sbjct 1092 EHSFNNFKMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPERI 1143
> dre:100332957 adenylate cyclase type 5-like
Length=1397
Score = 52.8 bits (125), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 26/66 (39%), Positives = 41/66 (62%), Gaps = 1/66 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M+E + VRE V +NMR+G+H G GV+G R+ ++D+W DV + N +E+ G G
Sbjct 474 MIEAISLVREVTGV-NVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAG 532
Query 63 QICCSK 68
+I +K
Sbjct 533 RIHITK 538
Score = 49.7 bits (117), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 22/52 (42%), Positives = 34/52 (65%), Gaps = 0/52 (0%)
Query 13 EMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQI 64
E M+IGL++G V GVIG+R+ +YD+WG V V + ++S G+P +I
Sbjct 1303 EHSFNNFKMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPERI 1354
Score = 48.1 bits (113), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 24/59 (40%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query 10 VREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSK 68
VRE V +NMR+G+H G GV+G R+ ++D+W DV + N +E+ G G+I +K
Sbjct 765 VREVTGV-NVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITK 822
> mmu:224129 Adcy5, AW121902, Ac5; adenylate cyclase 5 (EC:4.6.1.1);
K08045 adenylate cyclase 5 [EC:4.6.1.1]
Length=1262
Score = 52.8 bits (125), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 26/66 (39%), Positives = 41/66 (62%), Gaps = 1/66 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M+E + VRE V +NMR+G+H G GV+G R+ ++D+W DV + N +E+ G G
Sbjct 545 MIEAISLVREVTGV-NVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAG 603
Query 63 QICCSK 68
+I +K
Sbjct 604 RIHITK 609
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 21/46 (45%), Positives = 33/46 (71%), Gaps = 0/46 (0%)
Query 19 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQI 64
M+IGL++G V GVIG+R+ +YD+WG V V + ++S G+P +I
Sbjct 1174 FQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRI 1219
> hsa:111 ADCY5, AC5; adenylate cyclase 5 (EC:4.6.1.1); K08045
adenylate cyclase 5 [EC:4.6.1.1]
Length=911
Score = 52.8 bits (125), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 26/66 (39%), Positives = 41/66 (62%), Gaps = 1/66 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M+E + VRE V +NMR+G+H G GV+G R+ ++D+W DV + N +E+ G G
Sbjct 194 MIEAISLVREVTGV-NVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAG 252
Query 63 QICCSK 68
+I +K
Sbjct 253 RIHITK 258
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 22/63 (34%), Positives = 41/63 (65%), Gaps = 1/63 (1%)
Query 2 QMLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLP 61
++++ ++ + E M+IGL++G V GVIG+R+ +YD+WG V V + ++S G+P
Sbjct 807 KLMDQMKYINEH-SFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVP 865
Query 62 GQI 64
+I
Sbjct 866 DRI 868
> dre:570652 adcy6a, adcy6; adenylate cyclase 6a; K08046 adenylate
cyclase 6 [EC:4.6.1.1]
Length=1174
Score = 52.4 bits (124), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 26/66 (39%), Positives = 41/66 (62%), Gaps = 1/66 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M+E + VRE V +NMR+G+H G GV+G R+ ++D+W DV + N +E+ G G
Sbjct 452 MIEAISLVREVTGV-NVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAG 510
Query 63 QICCSK 68
+I +K
Sbjct 511 RIHITK 516
Score = 50.4 bits (119), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 24/68 (35%), Positives = 42/68 (61%), Gaps = 6/68 (8%)
Query 3 MLEHVEAVREEMQ------VPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIE 56
+ ++ +RE+M+ M+IGL++G V GVIG+R+ +YD+WG V V + ++
Sbjct 1064 LADYAMHLREQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMD 1123
Query 57 SNGLPGQI 64
S G+P +I
Sbjct 1124 STGVPDRI 1131
> hsa:115 ADCY9, AC9, FLJ12046; adenylate cyclase 9 (EC:4.6.1.1);
K08049 adenylate cyclase 9 [EC:4.6.1.1]
Length=1353
Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 27/101 (26%), Positives = 54/101 (53%), Gaps = 5/101 (4%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M++ +E +E + +NMR+G+H G+ + G++G RR ++D+W DV + N +E G+ G
Sbjct 469 MIKAIEQFCQEKK-EMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAG 527
Query 63 QI----CCSKEFKTAFQREEQSDLRCCDQHVAFVHLKNIRV 99
++ +K ++ E+ + Q V LK ++
Sbjct 528 KVHISEATAKYLDDRYEMEDGKVIERLGQSVVADQLKGLKT 568
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 20/69 (28%), Positives = 38/69 (55%), Gaps = 0/69 (0%)
Query 1 RQMLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGL 60
++M+ V+ M +R+G + G GVIG+ +L YD+WG V + + +++ G+
Sbjct 1143 KEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGV 1202
Query 61 PGQICCSKE 69
+I S+E
Sbjct 1203 ECRIQVSEE 1211
> mmu:11512 Adcy6, mKIAA0422; adenylate cyclase 6 (EC:4.6.1.1);
K08046 adenylate cyclase 6 [EC:4.6.1.1]
Length=1168
Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 25/62 (40%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M+E + VRE V +NMR+G+H G GV+G R+ ++D+W DV + N +E+ G G
Sbjct 454 MIEAISLVREVTGV-NVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGRAG 512
Query 63 QI 64
+I
Sbjct 513 RI 514
Score = 50.1 bits (118), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 23/63 (36%), Positives = 41/63 (65%), Gaps = 1/63 (1%)
Query 2 QMLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLP 61
+++E ++ + E M+IGL++G V GVIG+R+ +YD+WG V V + ++S G+P
Sbjct 1065 RLMEQMKHINEH-SFNNFQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVP 1123
Query 62 GQI 64
+I
Sbjct 1124 DRI 1126
> hsa:112 ADCY6, AC6, DKFZp779F075, KIAA0422; adenylate cyclase
6 (EC:4.6.1.1); K08046 adenylate cyclase 6 [EC:4.6.1.1]
Length=1168
Score = 51.6 bits (122), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 25/62 (40%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M+E + VRE V +NMR+G+H G GV+G R+ ++D+W DV + N +E+ G G
Sbjct 454 MIEAISLVREVTGV-NVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGRAG 512
Query 63 QI 64
+I
Sbjct 513 RI 514
Score = 49.7 bits (117), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 23/63 (36%), Positives = 41/63 (65%), Gaps = 1/63 (1%)
Query 2 QMLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLP 61
+++E ++ + E M+IGL++G V GVIG+R+ +YD+WG V V + ++S G+P
Sbjct 1065 RLMEQMKHINEH-SFNNFQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVP 1123
Query 62 GQI 64
+I
Sbjct 1124 DRI 1126
> mmu:11515 Adcy9, ACtp10, AW125421, D16Wsu65e, mKIAA0520; adenylate
cyclase 9 (EC:4.6.1.1); K08049 adenylate cyclase 9 [EC:4.6.1.1]
Length=1353
Score = 51.2 bits (121), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 31/101 (30%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M++ +E +E + +NMR+G+H G+ + G++G RR ++D+W DV + N +E G+ G
Sbjct 469 MIKAIEQFCQEKK-EMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAG 527
Query 63 QICCSKEF-KTAFQREEQSDLRCCD---QHVAFVHLKNIRV 99
++ S+ K R E D R + Q V LK ++
Sbjct 528 KVHISEATAKYLDDRYEMEDGRVIERLGQSVVADQLKGLKT 568
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 20/69 (28%), Positives = 38/69 (55%), Gaps = 0/69 (0%)
Query 1 RQMLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGL 60
++M+ V+ M +R+G + G GVIG+ +L YD+WG V + + +++ G+
Sbjct 1143 KEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGV 1202
Query 61 PGQICCSKE 69
+I S+E
Sbjct 1203 ECRIQVSEE 1211
> xla:378610 adcy9, xlAC; adenylate cyclase 9 (EC:4.6.1.1); K08049
adenylate cyclase 9 [EC:4.6.1.1]
Length=1355
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 25/71 (35%), Positives = 46/71 (64%), Gaps = 3/71 (4%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
M+E ++ +E + +NMR+G+H G+ + G++G RR ++D+W DV + N +E G+ G
Sbjct 513 MIEAIDQFCQEKK-EMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAG 571
Query 63 QICCSKEFKTA 73
++ S+ KTA
Sbjct 572 KVHISE--KTA 580
Score = 45.8 bits (107), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 21/69 (30%), Positives = 38/69 (55%), Gaps = 0/69 (0%)
Query 1 RQMLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGL 60
++M+ V+ M +RIG + G GVIG+ +L YD+WG V + + +++ G+
Sbjct 1184 KEMMSVVDEFNNNMLWFNFKLRIGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGV 1243
Query 61 PGQICCSKE 69
+I S+E
Sbjct 1244 ECRIQASEE 1252
> cel:T01A4.1 gcy-28; Guanylyl CYclase family member (gcy-28);
K12323 atrial natriuretic peptide receptor A [EC:4.6.1.2]
Length=1276
Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats.
Identities = 25/51 (49%), Positives = 35/51 (68%), Gaps = 0/51 (0%)
Query 19 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKE 69
L +RIG+H GS V GV+GS+ RY L+G V + +ESNGLP +I S++
Sbjct 1178 LKLRIGMHSGSVVAGVVGSKMPRYCLFGDTVNTSSRMESNGLPLKIHVSQQ 1228
> dre:100333538 adenylyl cyclase 35C-like
Length=597
Score = 50.8 bits (120), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 21/63 (33%), Positives = 40/63 (63%), Gaps = 4/63 (6%)
Query 2 QMLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLP 61
Q +E ++EM +NMR+G+H G+ + G++G +R ++D+W DV + N +E G+
Sbjct 504 QAIEQFCQEKKEM----VNMRVGIHTGTVLCGILGMKRFKFDVWSNDVNLANLMEQLGVA 559
Query 62 GQI 64
G++
Sbjct 560 GKV 562
> dre:568137 atrial natriuretic peptide receptor A-like
Length=584
Score = 49.3 bits (116), Expect = 8e-06, Method: Composition-based stats.
Identities = 29/87 (33%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
Query 1 RQMLEHVEAVRE----EMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIE 56
+ L+ V AVR+ M L +R G+H G CV GV+G + RY L+G V + +E
Sbjct 397 KMSLDLVAAVRQVPIPHMPTKRLQLRAGIHTGPCVAGVVGYKMPRYCLFGDTVNTASRME 456
Query 57 SNGLPGQICCSKEFKTAFQREEQSDLR 83
S LP +I S A ++ +L+
Sbjct 457 STSLPQKIHASSATYLALMKDNAYELQ 483
> cel:T07D1.1 gcy-31; Guanylyl CYclase family member (gcy-31)
Length=594
Score = 49.3 bits (116), Expect = 8e-06, Method: Composition-based stats.
Identities = 45/169 (26%), Positives = 73/169 (43%), Gaps = 14/169 (8%)
Query 3 MLEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPG 62
++E + V ++ +++R G+H GS V GV+G RY L+G V V N +E N P
Sbjct 403 LVEAGKMVNMNNKIHKIDIRAGVHSGSVVAGVVGLSMPRYCLFGETVYVANKMEQNSSPM 462
Query 63 QICCSKEFKTAFQREEQSDLRCCD-QHVAFVHLKNIRVIHREVTIFTV-----HSAFDAN 116
+I S +T + E+SD + + +K+ + I T F V H
Sbjct 463 KILVS---ETTHNKIEESDPGLYQFERREEIEIKDDQTIQ---TFFVVSRHGPHRVPSPR 516
Query 117 ICGIRRSNSQLAPSPPAMSNCPSRSSNRGVNDESRDSLPP--QLPFEPI 163
C R+ +SQ P +S + E+ + L QL F P+
Sbjct 517 NCESRQDDSQTEDDDDDELLLPRKSGRKSPTSEAEEELKKKGQLSFTPV 565
> cel:F23H12.6 gcy-13; Guanylyl CYclase family member (gcy-13);
K01769 guanylate cyclase, other [EC:4.6.1.2]
Length=1035
Score = 48.5 bits (114), Expect = 1e-05, Method: Composition-based stats.
Identities = 27/68 (39%), Positives = 39/68 (57%), Gaps = 3/68 (4%)
Query 19 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSK---EFKTAFQ 75
+ +RIG+H GSCV GV+G RY L+G V + +ESNG PG I S + T+
Sbjct 944 VQIRIGMHSGSCVAGVVGLTMPRYCLFGDTVNTASRMESNGKPGFIHLSSDCYDLLTSLY 1003
Query 76 REEQSDLR 83
+E ++ R
Sbjct 1004 KEYNTESR 1011
> cel:F21H7.9 gcy-20; Guanylyl CYclase family member (gcy-20);
K01769 guanylate cyclase, other [EC:4.6.1.2]
Length=1108
Score = 48.1 bits (113), Expect = 2e-05, Method: Composition-based stats.
Identities = 27/66 (40%), Positives = 39/66 (59%), Gaps = 7/66 (10%)
Query 4 LEHVEAVREEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQ 63
++H+ A R +N+RIG++ GS V GV+G RY L+G V + +ESNG PGQ
Sbjct 961 VQHLPAER-------INLRIGINCGSVVAGVVGLTMPRYCLFGDAVNTASRMESNGKPGQ 1013
Query 64 ICCSKE 69
I + E
Sbjct 1014 IHVTAE 1019
> cel:F22E5.3 gcy-21; Guanylyl CYclase family member (gcy-21);
K01769 guanylate cyclase, other [EC:4.6.1.2]
Length=1119
Score = 48.1 bits (113), Expect = 2e-05, Method: Composition-based stats.
Identities = 25/66 (37%), Positives = 41/66 (62%), Gaps = 1/66 (1%)
Query 3 MLEHVEAVR-EEMQVPGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLP 61
+L+ VE+ + + + +RIG++ G CV GV+G + RY L+G V + +ESNG+P
Sbjct 916 LLKAVESFKIRHLPNEKVRLRIGMNSGPCVAGVVGLKMPRYCLFGDTVNTASRMESNGIP 975
Query 62 GQICCS 67
+I CS
Sbjct 976 LRINCS 981
> cel:T03D8.5 gcy-22; Guanylyl CYclase family member (gcy-22);
K01769 guanylate cyclase, other [EC:4.6.1.2]
Length=1012
Score = 48.1 bits (113), Expect = 2e-05, Method: Composition-based stats.
Identities = 23/51 (45%), Positives = 32/51 (62%), Gaps = 0/51 (0%)
Query 19 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGLPGQICCSKE 69
+N+R+GLH G V GV+G RY L+G V + +ESNG PG++ S E
Sbjct 914 INIRVGLHTGPVVTGVVGMTMPRYCLFGDSVNTASRMESNGKPGRVHISTE 964
Lambda K H
0.323 0.137 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 4859948100
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
Posted date: Sep 17, 2011 2:57 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40