bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
164,496 sequences; 82,071,388 total letters
Query= Eten_1026_orf3
Length=335
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_016880 receptor for activated C kinase, RACK protei... 525 1e-148
pfa:PF08_0019 PfRACK; receptor for activated C kinase homolog,... 434 3e-121
tpv:TP04_0288 guanine nucleotide-binding protein; K14753 guani... 425 1e-118
cpv:cgd2_1870 guanine nucleotide-binding protein ; K14753 guan... 410 4e-114
dre:30722 gnb2l1, rack1, wu:fb80d08, wu:fk65d12; guanine nucle... 387 3e-107
bbo:BBOV_II003050 18.m06254; receptor for activated C kinase, ... 384 3e-106
xla:446289 MGC130692; hypothetical protein LOC446289; K00567 m... 384 4e-106
xla:379825 gnb2l1, MGC53289; guanine nucleotide binding protei... 384 4e-106
xla:495666 gnb2l1, gnb2-rs1, h12.3, hlc-7, pig21, rack1; guani... 380 3e-105
mmu:14694 Gnb2l1, AL033335, GB-like, Gnb2-rs1, Rack1, p205; gu... 380 3e-105
hsa:10399 GNB2L1, Gnb2-rs1, H12.3, HLC-7, PIG21, RACK1; guanin... 380 3e-105
ath:AT3G18130 RACK1C_AT (RECEPTOR FOR ACTIVATED C KINASE 1 C);... 375 2e-103
ath:AT1G18080 ATARCA; ATARCA; nucleotide binding; K14753 guani... 373 6e-103
cel:K04D7.1 rack-1; RACK1 (mammalian Receptor of Activated C K... 371 2e-102
ath:AT1G48630 RACK1B_AT (RECEPTOR FOR ACTIVATED C KINASE 1 B);... 371 2e-102
sce:YMR116C ASC1, CPC2; Asc1p; K14753 guanine nucleotide-bindi... 258 2e-68
hsa:25886 POC1A, DKFZp434C245, MGC131902, PIX2, WDR51A; POC1 c... 134 5e-31
mmu:70235 Poc1a, 2510040D07Rik, Wdr51a; POC1 centriolar protei... 133 9e-31
xla:734519 poc1b, MGC114911, pix1, tuwd12, wdr51b; POC1 centri... 129 1e-29
mmu:382406 Poc1b, 4933430F16Rik, Wdr51b; POC1 centriolar prote... 128 3e-29
dre:406322 poc1a, wdr51a, wu:fl82d01, zgc:56055; POC1 centriol... 124 6e-28
dre:386932 poc1b, TUWD12, fl36w17, wdr51b, wu:fl36w17, zgc:635... 120 5e-27
xla:379573 poc1a, MGC69111, pix2, wdr51a; POC1 centriolar prot... 120 8e-27
hsa:282809 POC1B, FLJ14923, FLJ41111, PIX1, TUWD12, WDR51B; PO... 116 1e-25
xla:399199 pafah1b1, lis2, mdcr, mds, pafah, pafah1b1-b; plate... 115 2e-25
mmu:18472 Pafah1b1, LIS-1, Lis1, MGC25297, MMS10-U, Mdsh, Ms10... 115 2e-25
hsa:5048 PAFAH1B1, LIS1, LIS2, MDCR, MDS, PAFAH; platelet-acti... 115 2e-25
dre:394247 pafah1b1b, Lis1a; platelet-activating factor acetyl... 114 6e-25
hsa:54554 WDR5B, FLJ11287, MGC49879; WD repeat domain 5B; K149... 109 1e-23
sce:YBR198C TAF5, TAF90; Taf5p; K03130 transcription initiatio... 109 1e-23
mmu:140858 Wdr5, 2410008O07Rik, AA408785, AA960360, Big, Big-3... 109 2e-23
hsa:11091 WDR5, BIG-3, SWD3; WD repeat domain 5; K14963 COMPAS... 109 2e-23
dre:394246 pafah1b1a; platelet-activating factor acetylhydrola... 109 2e-23
ath:AT3G49660 transducin family protein / WD-40 repeat family ... 108 2e-23
xla:446809 wdr5-a, MGC80538, big-3, swd3, xwdr5; WD repeat dom... 108 4e-23
dre:406372 wdr5, wu:fk47f04, zgc:56591, zgc:76895; WD repeat d... 108 4e-23
xla:447447 wdr5-b, MGC81485, big-3, swd3, wdr5, xwdr5; WD repe... 107 5e-23
mmu:69544 Wdr5b, 2310009C03Rik, AI606931; WD repeat domain 5B;... 106 1e-22
cel:C14B1.4 tag-125; Temporarily Assigned Gene name family mem... 104 5e-22
xla:734230 fbxw7; F-box and WD repeat domain containing 7; K10... 103 8e-22
hsa:55294 FBXW7, AGO, CDC4, DKFZp686F23254, FBW6, FBW7, FBX30,... 103 1e-21
dre:641491 taf5, MGC123129, wu:fc38g05, zgc:123129; TAF5 RNA p... 103 1e-21
dre:564991 fbxw7, si:ch211-208n2.1; F-box and WD repeat domain... 103 1e-21
mmu:50754 Fbxw7, 1110001A17Rik, AGO, Cdc4, Fbw7, Fbwd6, Fbx30,... 103 1e-21
dre:406291 katnb1, wu:fj32f02, wu:fj65h01, zgc:56071; katanin ... 102 2e-21
ath:AT4G02730 transducin family protein / WD-40 repeat family ... 101 4e-21
xla:734892 hypothetical protein MGC130867; K03130 transcriptio... 100 6e-21
xla:734280 wdr69, MGC85213; WD repeat domain 69 100 1e-20
mmu:226182 Taf5, 6330528C20Rik, AV117817; TAF5 RNA polymerase ... 99.8 1e-20
hsa:10300 KATNB1, KAT; katanin p80 (WD repeat containing) subu... 99.8 1e-20
> tgo:TGME49_016880 receptor for activated C kinase, RACK protein,
putative (EC:2.7.11.7); K14753 guanine nucleotide-binding
protein subunit beta-2-like 1 protein
Length=321
Score = 525 bits (1351), Expect = 1e-148, Method: Compositional matrix adjust.
Identities = 253/315 (80%), Positives = 287/315 (91%), Gaps = 1/315 (0%)
Query 20 VSVDSPLVFKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPN-AETVGFA 78
+S +SPL FKGVLEGHTD VTAISTP++KSNTI+SSSRD K+IVW LND+P+ + +VG+A
Sbjct 1 MSGESPLEFKGVLEGHTDCVTAISTPSLKSNTIVSSSRDHKVIVWTLNDNPDDSGSVGYA 60
Query 79 RRALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSA 138
RRALTGHSQCVQDVVI+SD FALSGSWDKTLRLWDLN G TVR+FQ HTSDVNSVAFS
Sbjct 61 RRALTGHSQCVQDVVINSDGQFALSGSWDKTLRLWDLNAGVTVRSFQGHTSDVNSVAFSP 120
Query 139 DNRQIVSGSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVK 198
DNRQIVSGSRDRT++LWNTLA+CKYTI + QH DWVSCVRFSPS +PLIVSCGWDKLVK
Sbjct 121 DNRQIVSGSRDRTIKLWNTLAECKYTIVDDQHNDWVSCVRFSPSANKPLIVSCGWDKLVK 180
Query 199 VWSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASCT 258
VW+L+ CKL TNLVGHTSVLYTVT+SPDGSLCASGGKDGVAMLWDV+EGKHLYSLD++ T
Sbjct 181 VWNLSNCKLRTNLVGHTSVLYTVTISPDGSLCASGGKDGVAMLWDVNEGKHLYSLDSNST 240
Query 259 INSLCFSPCNYWLCAATDKSVKIWDLENKNVLDDIHPDQPVKSGIPWCTSLNWSYDGRTL 318
IN+LCFSPCNYWLCAATDKSVKIWDLENKNVL +I P++ +SG PWCTSLNWS+DGRTL
Sbjct 241 INALCFSPCNYWLCAATDKSVKIWDLENKNVLSEITPEKTNRSGAPWCTSLNWSHDGRTL 300
Query 319 FIGTTSGNIHVYEVA 333
F+GT +G I+VYEV+
Sbjct 301 FVGTFTGAINVYEVS 315
> pfa:PF08_0019 PfRACK; receptor for activated C kinase homolog,
PfRACK; K14753 guanine nucleotide-binding protein subunit
beta-2-like 1 protein
Length=323
Score = 434 bits (1115), Expect = 3e-121, Method: Compositional matrix adjust.
Identities = 204/314 (64%), Positives = 258/314 (82%), Gaps = 2/314 (0%)
Query 23 DSPLVFKGVLEG-HTDWVTAISTPT-VKSNTIISSSRDKKIIVWNLNDSPNAETVGFARR 80
++ + +GVLEG H+DWVT++STPT K TI+S+SRDKK+IVWN+N ++ +G A++
Sbjct 7 EAEISLRGVLEGGHSDWVTSVSTPTDPKLKTIVSASRDKKLIVWNINTDDDSGEIGTAKK 66
Query 81 ALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADN 140
+LTGHSQ + DV ISSD FALSGSWD ++RLWDL++GET+R+F HTSDV SV+FS DN
Sbjct 67 SLTGHSQAINDVSISSDGLFALSGSWDHSVRLWDLSLGETIRSFIGHTSDVFSVSFSPDN 126
Query 141 RQIVSGSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVW 200
RQIVS SRD+T++LWNTLA CKYTI + QHTDW++CVRFSPSP + +IVSCGWDKLVKVW
Sbjct 127 RQIVSASRDKTIKLWNTLAQCKYTITDQQHTDWITCVRFSPSPNQAIIVSCGWDKLVKVW 186
Query 201 SLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASCTIN 260
+L C L NL GHT VL TVT+SPDGSLCASGGKDGVA LWDV EGKHLYSL+ TIN
Sbjct 187 NLKNCDLNKNLEGHTGVLNTVTISPDGSLCASGGKDGVAKLWDVKEGKHLYSLETGSTIN 246
Query 261 SLCFSPCNYWLCAATDKSVKIWDLENKNVLDDIHPDQPVKSGIPWCTSLNWSYDGRTLFI 320
SLCFSPC+YWLCAATD+ ++IW+LE+K ++ +I+P + K G+PWCTSL WS +G+ L+
Sbjct 247 SLCFSPCDYWLCAATDRFIRIWNLESKLIISEIYPVKQSKIGVPWCTSLTWSANGQLLYC 306
Query 321 GTTSGNIHVYEVAE 334
G+T GNI+VYEV +
Sbjct 307 GSTDGNIYVYEVKK 320
> tpv:TP04_0288 guanine nucleotide-binding protein; K14753 guanine
nucleotide-binding protein subunit beta-2-like 1 protein
Length=331
Score = 425 bits (1092), Expect = 1e-118, Method: Compositional matrix adjust.
Identities = 212/327 (64%), Positives = 251/327 (76%), Gaps = 5/327 (1%)
Query 10 FALSASAKMSVSVDSPLVFKGVLEG-HTDWVTAISTP-TVKSNTIISSSRDKKIIVWNLN 67
A A+ K+S SV L FKGVL G H WVT+ISTP NTIIS+SRDK++++W +
Sbjct 1 MASVATEKLSNSV---LEFKGVLSGGHHGWVTSISTPLKTDVNTIISASRDKRLMIWEMF 57
Query 68 DSPNAETVGFARRALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKH 127
D VG A+RALTGHSQ VQDV +SSD FALSGSWD TLRLWDL +VR F H
Sbjct 58 DEDVDGQVGVAKRALTGHSQTVQDVSMSSDGLFALSGSWDGTLRLWDLVKACSVRVFNGH 117
Query 128 TSDVNSVAFSADNRQIVSGSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPL 187
T DVNSVAFS DNRQI+SGSRD+T++LWNTLA+CKYTI HTDWVSCVRFSPS KEP+
Sbjct 118 TKDVNSVAFSPDNRQIISGSRDKTIKLWNTLAECKYTITNSTHTDWVSCVRFSPSGKEPI 177
Query 188 IVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEG 247
VS GWDKL+KVW L TC+L L GH V+Y+V++SPDGSLCASGGKDGVA LWD+ E
Sbjct 178 FVSGGWDKLIKVWDLRTCQLKHTLYGHEGVVYSVSISPDGSLCASGGKDGVARLWDMKEA 237
Query 248 KHLYSLDASCTINSLCFSPCNYWLCAATDKSVKIWDLENKNVLDDIHPDQPVKSGIPWCT 307
L+ LDA TIN+LCFSPCNYWLCAATDK++KIWDLENKN+L +I+ D+ K G+PWC
Sbjct 238 NSLHLLDAGSTINALCFSPCNYWLCAATDKAIKIWDLENKNILAEINNDRTKKVGLPWCV 297
Query 308 SLNWSYDGRTLFIGTTSGNIHVYEVAE 334
SL WS DGR L+ G+T GNI+VY+V+
Sbjct 298 SLCWSPDGRVLYAGSTDGNIYVYQVSR 324
> cpv:cgd2_1870 guanine nucleotide-binding protein ; K14753 guanine
nucleotide-binding protein subunit beta-2-like 1 protein
Length=313
Score = 410 bits (1054), Expect = 4e-114, Method: Compositional matrix adjust.
Identities = 194/312 (62%), Positives = 249/312 (79%), Gaps = 2/312 (0%)
Query 22 VDSPLVFKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDS-PNAETVGFARR 80
++S L + G L GH+DWVT+I+ P S+ ++S+SRDK ++VWNL+D+ + ++G A+
Sbjct 1 MESSLEYIGCLSGHSDWVTSIAAPPDNSDIVVSASRDKSVLVWNLSDANKDQHSIGSAKT 60
Query 81 ALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADN 140
LTGH+Q V DV +SSD ++ +SGS DKTLRL+D+N G++VR F HTSDV SVA S DN
Sbjct 61 RLTGHNQAVNDVAVSSDGSYVVSGSCDKTLRLFDVNAGKSVRNFVGHTSDVFSVALSPDN 120
Query 141 RQIVSGSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVW 200
RQI+SGSRD T+++WN + C YT+ +GQH DWVSCVRFSPS +PL VSCGWDK+VKVW
Sbjct 121 RQIISGSRDHTIKVWNAMGVCMYTLLDGQHNDWVSCVRFSPSTSQPLFVSCGWDKIVKVW 180
Query 201 SLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASCTIN 260
S K T NLVGH+SVLYTVT++PDGSLCASGGKDGV MLWDVSEGKHLYSLDA+ +IN
Sbjct 181 S-HEFKPTCNLVGHSSVLYTVTIAPDGSLCASGGKDGVVMLWDVSEGKHLYSLDANHSIN 239
Query 261 SLCFSPCNYWLCAATDKSVKIWDLENKNVLDDIHPDQPVKSGIPWCTSLNWSYDGRTLFI 320
+LCFSPCNYWLCAATDK ++IW+LE+K + + P P+K+G+PWC SL WS DG+TLF
Sbjct 240 ALCFSPCNYWLCAATDKCIRIWELEHKLPVAEFAPPAPIKNGLPWCVSLTWSNDGKTLFA 299
Query 321 GTTSGNIHVYEV 332
G+T NI+VY+V
Sbjct 300 GSTDSNIYVYKV 311
> dre:30722 gnb2l1, rack1, wu:fb80d08, wu:fk65d12; guanine nucleotide
binding protein (G protein), beta polypeptide 2-like
1; K14753 guanine nucleotide-binding protein subunit beta-2-like
1 protein
Length=317
Score = 387 bits (994), Expect = 3e-107, Method: Compositional matrix adjust.
Identities = 194/313 (61%), Positives = 230/313 (73%), Gaps = 5/313 (1%)
Query 26 LVFKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGH 85
+ +G L+GH+ WVT I+T + I+S+SRDK II+W L + + G +RAL GH
Sbjct 5 MTVRGTLKGHSGWVTQIATTPQFPDMILSASRDKTIIMWKL--TRDETNYGIPQRALRGH 62
Query 86 SQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVS 145
S V DVVISSD FALSGSWD TLRLWDL G T R F HT DV SVAFSADNRQIVS
Sbjct 63 SHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSADNRQIVS 122
Query 146 GSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTC 205
GSRD+T++LWNTL CKYTI++ HT+WVSCVRFSP+ P+IVSCGWDK+VKVW+L C
Sbjct 123 GSRDKTIKLWNTLGVCKYTIQDDSHTEWVSCVRFSPNSSNPIIVSCGWDKMVKVWNLANC 182
Query 206 KLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASCTINSLCFS 265
KL TN +GHT L TVTVSPDGSLCASGGKDG AMLWD++EGKHLY+LD TIN+LCFS
Sbjct 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDTINALCFS 242
Query 266 PCNYWLCAATDKSVKIWDLENKNVLDDIHPD---QPVKSGIPWCTSLNWSYDGRTLFIGT 322
P YWLCAAT S+KIWDLE K ++D++ D K+ P CTSL WS DG+TLF G
Sbjct 243 PNRYWLCAATGPSIKIWDLEGKIIVDELRQDIITTNSKAEPPQCTSLAWSADGQTLFAGY 302
Query 323 TSGNIHVYEVAEG 335
T I V++V G
Sbjct 303 TDNLIRVWQVTIG 315
> bbo:BBOV_II003050 18.m06254; receptor for activated C kinase,
RACK protein; K14753 guanine nucleotide-binding protein subunit
beta-2-like 1 protein
Length=322
Score = 384 bits (986), Expect = 3e-106, Method: Compositional matrix adjust.
Identities = 187/312 (59%), Positives = 234/312 (75%), Gaps = 3/312 (0%)
Query 23 DSPLVFKGVLEG-HTDWVTAISTPTVKS-NTIISSSRDKKIIVWNLNDSPNAETVGFARR 80
+S L +KGVL G HT WVTAIS P NT+IS+SRDKKI++W + D+ +G A++
Sbjct 3 NSVLDYKGVLTGGHTGWVTAISCPGRSDINTVISASRDKKIMIWEVYDNEIEGEIGIAKK 62
Query 81 ALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADN 140
+LTGHSQ +QDV +S D FALSGSWD TLRLWDL +TV + HTSDV SV FS DN
Sbjct 63 SLTGHSQTIQDVTMSFDGLFALSGSWDNTLRLWDLVKCKTVHVYNGHTSDVYSVDFSPDN 122
Query 141 RQIVSGSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVW 200
RQI+S SRD+T++LWNTL++CK T++ H DWVSCVRFSP+P E + VS GWDK+VKVW
Sbjct 123 RQIISASRDKTIKLWNTLSECKRTVQNA-HNDWVSCVRFSPNPHEHVFVSGGWDKIVKVW 181
Query 201 SLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASCTIN 260
L C L NL GH ++ ++SPDGSLCASGGKDG+A LWD+ EG L+ L+A IN
Sbjct 182 DLANCNLKFNLSGHEGIVSCTSISPDGSLCASGGKDGIARLWDMKEGNSLHLLEAGSPIN 241
Query 261 SLCFSPCNYWLCAATDKSVKIWDLENKNVLDDIHPDQPVKSGIPWCTSLNWSYDGRTLFI 320
+LCFSPCNYWLC ATD+++KIW+LENKNVL +I D+P K G+PWC SL W+ DG TLF
Sbjct 242 ALCFSPCNYWLCVATDRAIKIWNLENKNVLAEITSDKPKKIGLPWCVSLCWNADGSTLFA 301
Query 321 GTTSGNIHVYEV 332
G+T G I+VY+V
Sbjct 302 GSTDGTIYVYQV 313
> xla:446289 MGC130692; hypothetical protein LOC446289; K00567
methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
Length=317
Score = 384 bits (985), Expect = 4e-106, Method: Compositional matrix adjust.
Identities = 190/313 (60%), Positives = 229/313 (73%), Gaps = 5/313 (1%)
Query 26 LVFKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGH 85
+ +G L+GH WVT I+T + I+SSSRDK +I+W L + + G +RAL GH
Sbjct 5 MTLRGTLKGHNGWVTQIATTPQFPDMILSSSRDKSVIMWKL--TRDETNYGVPQRALRGH 62
Query 86 SQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVS 145
S V DVVISSD FALSGSWD TLRLWDL G T R F HT DV SVAFSADNRQIVS
Sbjct 63 SHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSADNRQIVS 122
Query 146 GSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTC 205
GSRD+T++LWNTL CKYT++E H++WVSCVRFSP+ P+IVSCGWDK+VKVW+L C
Sbjct 123 GSRDKTIKLWNTLGVCKYTVQEESHSEWVSCVRFSPNSSNPIIVSCGWDKMVKVWNLANC 182
Query 206 KLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASCTINSLCFS 265
KL TN +GH+ L TVTVSPDGSLCASGGKDG AMLWD++EGKHLY+LD+ IN+LCFS
Sbjct 183 KLKTNHIGHSGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDSGDVINALCFS 242
Query 266 PCNYWLCAATDKSVKIWDLENKNVLDDIHPD---QPVKSGIPWCTSLNWSYDGRTLFIGT 322
P YWLCAAT S+KIWDLE K ++D++ + K+ P CTSL WS DG+TLF G
Sbjct 243 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISSSSKAEPPQCTSLAWSADGQTLFAGY 302
Query 323 TSGNIHVYEVAEG 335
T I V++V G
Sbjct 303 TDNLIRVWQVTIG 315
> xla:379825 gnb2l1, MGC53289; guanine nucleotide binding protein,
beta 2, related sequence 1; K14753 guanine nucleotide-binding
protein subunit beta-2-like 1 protein
Length=317
Score = 384 bits (985), Expect = 4e-106, Method: Compositional matrix adjust.
Identities = 190/313 (60%), Positives = 229/313 (73%), Gaps = 5/313 (1%)
Query 26 LVFKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGH 85
+ +G L+GH WVT I+T + I+SSSRDK +I+W L + + G +RAL GH
Sbjct 5 MTLRGTLKGHNGWVTQIATTPQFPDMILSSSRDKSVIMWKL--TRDETNYGVPQRALRGH 62
Query 86 SQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVS 145
S V DVVISSD FALSGSWD TLRLWDL G T R F HT DV SVAFSADNRQIVS
Sbjct 63 SHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSADNRQIVS 122
Query 146 GSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTC 205
GSRD+T++LWNTL CKYT++E H++WVSCVRFSP+ P+IVSCGWDK+VKVW+L C
Sbjct 123 GSRDKTIKLWNTLGVCKYTVQEESHSEWVSCVRFSPNSSNPIIVSCGWDKMVKVWNLANC 182
Query 206 KLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASCTINSLCFS 265
KL TN +GH+ L TVTVSPDGSLCASGGKDG AMLWD++EGKHLY+LD+ IN+LCFS
Sbjct 183 KLKTNHIGHSGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDSGDVINALCFS 242
Query 266 PCNYWLCAATDKSVKIWDLENKNVLDDIHPD---QPVKSGIPWCTSLNWSYDGRTLFIGT 322
P YWLCAAT S+KIWDLE K ++D++ + K+ P CTSL WS DG+TLF G
Sbjct 243 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISSSSKAEPPQCTSLAWSADGQTLFAGY 302
Query 323 TSGNIHVYEVAEG 335
T I V++V G
Sbjct 303 TDNLIRVWQVTIG 315
> xla:495666 gnb2l1, gnb2-rs1, h12.3, hlc-7, pig21, rack1; guanine
nucleotide binding protein (G protein), beta polypeptide
2-like 1; K14753 guanine nucleotide-binding protein subunit
beta-2-like 1 protein
Length=317
Score = 380 bits (977), Expect = 3e-105, Method: Compositional matrix adjust.
Identities = 189/313 (60%), Positives = 228/313 (72%), Gaps = 5/313 (1%)
Query 26 LVFKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGH 85
+ +G L+GH WVT I+T + I+S+SRDK II+W L + + G +RAL GH
Sbjct 5 MTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKL--TRDETNYGIPQRALRGH 62
Query 86 SQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVS 145
S V DVVISSD FALSGSWD TLRLWDL G T R F HT DV SVAFS+DNRQIVS
Sbjct 63 SHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 122
Query 146 GSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTC 205
GSRD+T++LWNTL CKYT+++ H++WVSCVRFSP+ P+IVSCGWDKLVKVW+L C
Sbjct 123 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query 206 KLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASCTINSLCFS 265
KL TN +GHT L TVTVSPDGSLCASGGKDG AMLWD++EGKHLY+LD IN+LCFS
Sbjct 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS 242
Query 266 PCNYWLCAATDKSVKIWDLENKNVLDDIHPD---QPVKSGIPWCTSLNWSYDGRTLFIGT 322
P YWLCAAT S+KIWDLE K ++D++ + K+ P CTSL WS DG+TLF G
Sbjct 243 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGY 302
Query 323 TSGNIHVYEVAEG 335
T + V++V G
Sbjct 303 TDNLVRVWQVTIG 315
> mmu:14694 Gnb2l1, AL033335, GB-like, Gnb2-rs1, Rack1, p205;
guanine nucleotide binding protein (G protein), beta polypeptide
2 like 1; K14753 guanine nucleotide-binding protein subunit
beta-2-like 1 protein
Length=317
Score = 380 bits (977), Expect = 3e-105, Method: Compositional matrix adjust.
Identities = 189/313 (60%), Positives = 228/313 (72%), Gaps = 5/313 (1%)
Query 26 LVFKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGH 85
+ +G L+GH WVT I+T + I+S+SRDK II+W L + + G +RAL GH
Sbjct 5 MTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKL--TRDETNYGIPQRALRGH 62
Query 86 SQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVS 145
S V DVVISSD FALSGSWD TLRLWDL G T R F HT DV SVAFS+DNRQIVS
Sbjct 63 SHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 122
Query 146 GSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTC 205
GSRD+T++LWNTL CKYT+++ H++WVSCVRFSP+ P+IVSCGWDKLVKVW+L C
Sbjct 123 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query 206 KLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASCTINSLCFS 265
KL TN +GHT L TVTVSPDGSLCASGGKDG AMLWD++EGKHLY+LD IN+LCFS
Sbjct 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS 242
Query 266 PCNYWLCAATDKSVKIWDLENKNVLDDIHPD---QPVKSGIPWCTSLNWSYDGRTLFIGT 322
P YWLCAAT S+KIWDLE K ++D++ + K+ P CTSL WS DG+TLF G
Sbjct 243 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGY 302
Query 323 TSGNIHVYEVAEG 335
T + V++V G
Sbjct 303 TDNLVRVWQVTIG 315
> hsa:10399 GNB2L1, Gnb2-rs1, H12.3, HLC-7, PIG21, RACK1; guanine
nucleotide binding protein (G protein), beta polypeptide
2-like 1; K14753 guanine nucleotide-binding protein subunit
beta-2-like 1 protein
Length=317
Score = 380 bits (977), Expect = 3e-105, Method: Compositional matrix adjust.
Identities = 189/313 (60%), Positives = 228/313 (72%), Gaps = 5/313 (1%)
Query 26 LVFKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGH 85
+ +G L+GH WVT I+T + I+S+SRDK II+W L + + G +RAL GH
Sbjct 5 MTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKL--TRDETNYGIPQRALRGH 62
Query 86 SQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVS 145
S V DVVISSD FALSGSWD TLRLWDL G T R F HT DV SVAFS+DNRQIVS
Sbjct 63 SHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 122
Query 146 GSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTC 205
GSRD+T++LWNTL CKYT+++ H++WVSCVRFSP+ P+IVSCGWDKLVKVW+L C
Sbjct 123 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query 206 KLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASCTINSLCFS 265
KL TN +GHT L TVTVSPDGSLCASGGKDG AMLWD++EGKHLY+LD IN+LCFS
Sbjct 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS 242
Query 266 PCNYWLCAATDKSVKIWDLENKNVLDDIHPD---QPVKSGIPWCTSLNWSYDGRTLFIGT 322
P YWLCAAT S+KIWDLE K ++D++ + K+ P CTSL WS DG+TLF G
Sbjct 243 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGY 302
Query 323 TSGNIHVYEVAEG 335
T + V++V G
Sbjct 303 TDNLVRVWQVTIG 315
> ath:AT3G18130 RACK1C_AT (RECEPTOR FOR ACTIVATED C KINASE 1 C);
nucleotide binding; K14753 guanine nucleotide-binding protein
subunit beta-2-like 1 protein
Length=326
Score = 375 bits (962), Expect = 2e-103, Method: Compositional matrix adjust.
Identities = 191/323 (59%), Positives = 233/323 (72%), Gaps = 16/323 (4%)
Query 26 LVFKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGH 85
LV KG++ HTD VTAI+TP S+ I+++SRDK II+W L + + ++ G A+R LTGH
Sbjct 5 LVLKGIMRAHTDIVTAIATPIDNSDIIVTASRDKSIILWKL--TKDDKSYGVAQRRLTGH 62
Query 86 SQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVS 145
S V+DVV+SSD FALSGSWD LRLWDL GET R F HT DV SVAFS DNRQIVS
Sbjct 63 SHFVEDVVLSSDGQFALSGSWDGELRLWDLATGETTRRFVGHTKDVLSVAFSTDNRQIVS 122
Query 146 GSRDRTVRLWNTLADCKYTIEEGQ-HTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTT 204
SRDRT++LWNTL +CKYTI EG H +WVSCVRFSP+ P IVS WDK VKVW+L
Sbjct 123 ASRDRTIKLWNTLGECKYTISEGDGHKEWVSCVRFSPNTLVPTIVSASWDKTVKVWNLQN 182
Query 205 CKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASCTINSLCF 264
CKL +LVGH+ L TV VSPDGSLCASGGKDGV +LWD++EGK LYSL+A I+SLCF
Sbjct 183 CKLRNSLVGHSGYLNTVAVSPDGSLCASGGKDGVILLWDLAEGKKLYSLEAGSIIHSLCF 242
Query 265 SPCNYWLCAATDKSVKIWDLENKNVLDDIHPDQP---------VKSG----IPWCTSLNW 311
SP YWLCAAT+ S++IWDLE+K+V++D+ D V +G + +CTSLNW
Sbjct 243 SPNRYWLCAATENSIRIWDLESKSVVEDLKVDLKSEAEKNEGGVGTGNQKKVIYCTSLNW 302
Query 312 SYDGRTLFIGTTSGNIHVYEVAE 334
S DG TLF G T G + V+ +
Sbjct 303 SADGSTLFSGYTDGVVRVWGIGR 325
> ath:AT1G18080 ATARCA; ATARCA; nucleotide binding; K14753 guanine
nucleotide-binding protein subunit beta-2-like 1 protein
Length=327
Score = 373 bits (957), Expect = 6e-103, Method: Compositional matrix adjust.
Identities = 188/324 (58%), Positives = 227/324 (70%), Gaps = 17/324 (5%)
Query 26 LVFKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGH 85
LV KG + HTD VTAI+TP ++ I+S+SRDK II+W L A G A+R LTGH
Sbjct 5 LVLKGTMRAHTDMVTAIATPIDNADIIVSASRDKSIILWKLTKDDKA--YGVAQRRLTGH 62
Query 86 SQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVS 145
S V+DVV+SSD FALSGSWD LRLWDL G + R F HT DV SVAFS DNRQIVS
Sbjct 63 SHFVEDVVLSSDGQFALSGSWDGELRLWDLAAGVSTRRFVGHTKDVLSVAFSLDNRQIVS 122
Query 146 GSRDRTVRLWNTLADCKYTIEEGQ--HTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLT 203
SRDRT++LWNTL +CKYTI EG H DWVSCVRFSP+ +P IVS WDK VKVW+L+
Sbjct 123 ASRDRTIKLWNTLGECKYTISEGGEGHRDWVSCVRFSPNTLQPTIVSASWDKTVKVWNLS 182
Query 204 TCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASCTINSLC 263
CKL + L GHT + TV VSPDGSLCASGGKDGV +LWD++EGK LYSL+A+ I++LC
Sbjct 183 NCKLRSTLAGHTGYVSTVAVSPDGSLCASGGKDGVVLLWDLAEGKKLYSLEANSVIHALC 242
Query 264 FSPCNYWLCAATDKSVKIWDLENKNVLDDIHPD-------------QPVKSGIPWCTSLN 310
FSP YWLCAAT+ +KIWDLE+K++++D+ D K + +CTSLN
Sbjct 243 FSPNRYWLCAATEHGIKIWDLESKSIVEDLKVDLKAEAEKADNSGPAATKRKVIYCTSLN 302
Query 311 WSYDGRTLFIGTTSGNIHVYEVAE 334
WS DG TLF G T G I V+ +
Sbjct 303 WSADGSTLFSGYTDGVIRVWGIGR 326
> cel:K04D7.1 rack-1; RACK1 (mammalian Receptor of Activated C
Kinase) homolog family member (rack-1); K14753 guanine nucleotide-binding
protein subunit beta-2-like 1 protein
Length=325
Score = 371 bits (953), Expect = 2e-102, Method: Compositional matrix adjust.
Identities = 190/319 (59%), Positives = 233/319 (73%), Gaps = 7/319 (2%)
Query 22 VDSPLVFKGVLEGHTDWVTAISTPTVKSNT-IISSSRDKKIIVWNLND-SPNAE-TVGFA 78
V + G LEGHT WVT I+T T T ++SSSRDK I+VW+++ +P E +G
Sbjct 2 VQEQMKLTGTLEGHTGWVTQIATYTRNDKTTVLSSSRDKTILVWDVDSVAPVDEGPIGRP 61
Query 79 RRALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSA 138
R+LTGH+ V DVVISSD FALSGSWDKTLRLWDLN G + R F HT DV SVAFSA
Sbjct 62 VRSLTGHNHFVSDVVISSDGQFALSGSWDKTLRLWDLNQGVSTRQFISHTKDVLSVAFSA 121
Query 139 DNRQIVSGSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVK 198
DNRQIVSGSRD++++LWNTLA CKYTI + HTDWVS VRFSPS ++P+IVS GWDK+VK
Sbjct 122 DNRQIVSGSRDKSIKLWNTLAQCKYTITDDCHTDWVSTVRFSPSNRDPVIVSAGWDKVVK 181
Query 199 VWSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASCT 258
VW+L C+L TN +GHT + TVTVSPDGSLCASGGKDG AMLWD++EGKHLY+L +
Sbjct 182 VWNLGNCRLKTNHIGHTGYVNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLPGNDV 241
Query 259 INSLCFSPCNYWLCAATDKSVKIWDLENKNVLDDIHPD----QPVKSGIPWCTSLNWSYD 314
IN++ FSP YWLCAA S+KIWDLE+K ++++ P+ + P C SL WS D
Sbjct 242 INAMSFSPNRYWLCAAVGSSIKIWDLEDKKEIEELKPEIASSGSSRGSSPQCISLAWSQD 301
Query 315 GRTLFIGTTSGNIHVYEVA 333
G+TLF G T I VY+V+
Sbjct 302 GQTLFAGYTDNIIRVYQVS 320
> ath:AT1G48630 RACK1B_AT (RECEPTOR FOR ACTIVATED C KINASE 1 B);
nucleotide binding; K14753 guanine nucleotide-binding protein
subunit beta-2-like 1 protein
Length=326
Score = 371 bits (952), Expect = 2e-102, Method: Compositional matrix adjust.
Identities = 189/323 (58%), Positives = 227/323 (70%), Gaps = 16/323 (4%)
Query 26 LVFKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGH 85
LV KG + HTD VTAI+TP S+ I++SSRDK II+W L + ++ G A+R +TGH
Sbjct 5 LVLKGTMCAHTDMVTAIATPVDNSDVIVTSSRDKSIILWKL--TKEDKSYGVAQRRMTGH 62
Query 86 SQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVS 145
S VQDVV+SSD FALSGSWD LRLWDL GE+ R F HT DV SVAFS DNRQIVS
Sbjct 63 SHFVQDVVLSSDGQFALSGSWDGELRLWDLATGESTRRFVGHTKDVLSVAFSTDNRQIVS 122
Query 146 GSRDRTVRLWNTLADCKYTIEEGQ-HTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTT 204
SRDRT++LWNTL +CKYTI E H +WVSCVRFSP+ P IVS WDK VKVW+L
Sbjct 123 ASRDRTIKLWNTLGECKYTISEADGHKEWVSCVRFSPNTLVPTIVSASWDKTVKVWNLQN 182
Query 205 CKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASCTINSLCF 264
CKL L GH+ L TV VSPDGSLCASGGKDGV +LWD++EGK LYSL+A I+SLCF
Sbjct 183 CKLRNTLAGHSGYLNTVAVSPDGSLCASGGKDGVILLWDLAEGKKLYSLEAGSIIHSLCF 242
Query 265 SPCNYWLCAATDKSVKIWDLENKNVLDDIHPDQPV-------------KSGIPWCTSLNW 311
SP YWLCAAT+ S++IWDLE+K+V++D+ D K+ + +CTSLNW
Sbjct 243 SPNRYWLCAATENSIRIWDLESKSVVEDLKVDLKAEAEKTDGSTGIGNKTKVIYCTSLNW 302
Query 312 SYDGRTLFIGTTSGNIHVYEVAE 334
S DG TLF G T G I V+ +
Sbjct 303 SADGNTLFSGYTDGVIRVWGIGR 325
> sce:YMR116C ASC1, CPC2; Asc1p; K14753 guanine nucleotide-binding
protein subunit beta-2-like 1 protein
Length=319
Score = 258 bits (659), Expect = 2e-68, Method: Compositional matrix adjust.
Identities = 135/313 (43%), Positives = 190/313 (60%), Gaps = 10/313 (3%)
Query 26 LVFKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGH 85
LV +G LEGH WVT+++T + N ++S+SRDK +I W L + + + G R+ GH
Sbjct 7 LVLRGTLEGHNGWVTSLATSAGQPNLLLSASRDKTLISWKL--TGDDQKFGVPVRSFKGH 64
Query 86 SQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVS 145
S VQD +++D +ALS SWDKTLRLWD+ GET + F H SDV SV I+S
Sbjct 65 SHIVQDCTLTADGAYALSASWDKTLRLWDVATGETYQRFVGHKSDVMSVDIDKKASMIIS 124
Query 146 GSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEP----LIVSCGWDKLVKVWS 201
GSRD+T+++W C T+ H DWVS VR P+ K I+S G DK+VK W+
Sbjct 125 GSRDKTIKVWTIKGQCLATLL--GHNDWVSQVRVVPNEKADDDSVTIISAGNDKMVKAWN 182
Query 202 LTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASCTINS 261
L ++ + +GH S + T+T SPDG+L AS GKDG MLW+++ K +Y+L A + S
Sbjct 183 LNQFQIEADFIGHNSNINTLTASPDGTLIASAGKDGEIMLWNLAAKKAMYTLSAQDEVFS 242
Query 262 LCFSPCNYWLCAATDKSVKIWDLENKNVLDDIHPDQP--VKSGIPWCTSLNWSYDGRTLF 319
L FSP YWL AAT +K++ L+ + ++DD+ P+ K+ P SL WS DG+TLF
Sbjct 243 LAFSPNRYWLAAATATGIKVFSLDPQYLVDDLRPEFAGYSKAAEPHAVSLAWSADGQTLF 302
Query 320 IGTTSGNIHVYEV 332
G T I V++V
Sbjct 303 AGYTDNVIRVWQV 315
Score = 37.7 bits (86), Expect = 0.055, Method: Compositional matrix adjust.
Identities = 41/181 (22%), Positives = 63/181 (34%), Gaps = 62/181 (34%)
Query 32 LEGHTDWVTAIST-PTVKSN----TIISSSRDKKIIVWNLNDSPNAETVGFARRA-LTGH 85
L GH DWV+ + P K++ TIIS+ DK + WNLN F A GH
Sbjct 144 LLGHNDWVSQVRVVPNEKADDDSVTIISAGNDKMVKAWNLNQ--------FQIEADFIGH 195
Query 86 SQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTF--------------------- 124
+ + + S D S D + LW+L + + T
Sbjct 196 NSNINTLTASPDGTLIASAGKDGEIMLWNLAAKKAMYTLSAQDEVFSLAFSPNRYWLAAA 255
Query 125 ------------QKHTSDVN---------------SVAFSADNRQIVSGSRDRTVRLWNT 157
Q D+ S+A+SAD + + +G D +R+W
Sbjct 256 TATGIKVFSLDPQYLVDDLRPEFAGYSKAAEPHAVSLAWSADGQTLFAGYTDNVIRVWQV 315
Query 158 L 158
+
Sbjct 316 M 316
> hsa:25886 POC1A, DKFZp434C245, MGC131902, PIX2, WDR51A; POC1
centriolar protein homolog A (Chlamydomonas)
Length=359
Score = 134 bits (337), Expect = 5e-31, Method: Compositional matrix adjust.
Identities = 90/269 (33%), Positives = 134/269 (49%), Gaps = 15/269 (5%)
Query 32 LEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQD 91
+GH D VT + ++ + + S S D ++VW++ P + F TGH V
Sbjct 15 FKGHRDAVTCVDF-SINTKQLASGSMDSCLMVWHMK--PQSRAYRF-----TGHKDAVTC 66
Query 92 VVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRT 151
V S + SGS DKT+R+W NV F+ HT+ V SV F +D + V+ S D+T
Sbjct 67 VNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKT 126
Query 152 VRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTNL 211
V++W T K+ QH +WV C +FSP + LIVS DK VK+W ++ + +
Sbjct 127 VKVWATHRQ-KFLFSLSQHINWVRCAKFSPDGR--LIVSASDDKTVKLWDKSSRECVHSY 183
Query 212 VGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHL--YSLDASCTINSLCFSPC-N 268
H + V P G+ A+ G D +WDV + L Y L S +N L F P N
Sbjct 184 CEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLH-SAAVNGLSFHPSGN 242
Query 269 YWLCAATDKSVKIWDLENKNVLDDIHPDQ 297
Y + A++D ++KI DL +L +H Q
Sbjct 243 YLITASSDSTLKILDLMEGRLLYTLHGHQ 271
Score = 75.1 bits (183), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 72/253 (28%), Positives = 108/253 (42%), Gaps = 57/253 (22%)
Query 34 GHTDWVTAIS-TPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQDV 92
GH D VT ++ +P+ + + S SRDK + +W PN + RA H+ V+ V
Sbjct 59 GHKDAVTCVNFSPS--GHLLASGSRDKTVRIW----VPNVKGESTVFRA---HTATVRSV 109
Query 93 VISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRTV 152
SD ++ S DKT+++W + + + + +H + V FS D R IVS S D+TV
Sbjct 110 HFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTV 169
Query 153 RLWNTLA-DCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTN- 210
+LW+ + +C ++ E H +V+ V F PS I + G D VKVW + T +L +
Sbjct 170 KLWDKSSRECVHSYCE--HGGFVTYVDFHPSGT--CIAAAGMDNTVKVWDVRTHRLLQHY 225
Query 211 -----------------------------------------LVGHTSVLYTVTVSPDGSL 229
L GH TV S G
Sbjct 226 QLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEY 285
Query 230 CASGGKDGVAMLW 242
ASGG D M+W
Sbjct 286 FASGGSDEQVMVW 298
Score = 43.5 bits (101), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 0/76 (0%)
Query 85 HSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIV 144
HS V + N+ ++ S D TL++ DL G + T H +VAFS
Sbjct 228 HSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFA 287
Query 145 SGSRDRTVRLWNTLAD 160
SG D V +W + D
Sbjct 288 SGGSDEQVMVWKSNFD 303
Score = 33.5 bits (75), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 8/81 (9%)
Query 207 LTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSL----DASCTINSL 262
L + GH + V S + ASG D M+W + Y DA +N
Sbjct 11 LERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVN-- 68
Query 263 CFSPCNYWLCAAT-DKSVKIW 282
FSP + L + + DK+V+IW
Sbjct 69 -FSPSGHLLASGSRDKTVRIW 88
> mmu:70235 Poc1a, 2510040D07Rik, Wdr51a; POC1 centriolar protein
homolog A (Chlamydomonas)
Length=405
Score = 133 bits (335), Expect = 9e-31, Method: Compositional matrix adjust.
Identities = 88/269 (32%), Positives = 136/269 (50%), Gaps = 15/269 (5%)
Query 32 LEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQD 91
+GH D VT + ++ + + S S D +++W++ P + F TGH V
Sbjct 15 FKGHRDAVTCVDF-SLNTKHLASGSMDSTLMIWHMK--PQSRAYRF-----TGHKDAVTC 66
Query 92 VVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRT 151
V S + SGS DKT+R+W NV F+ HT+ V SV F +D + +V+ S D+T
Sbjct 67 VNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKT 126
Query 152 VRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTNL 211
V++W+T ++ QH +WV C +FSP + LIVS DK VK+W T+ + +
Sbjct 127 VKVWSTHRQ-RFLFSLTQHINWVRCAKFSPDGR--LIVSASDDKTVKLWDKTSRECIHSY 183
Query 212 VGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHL--YSLDASCTINSLCFSPC-N 268
H + V P G+ A+ G D +WD + L Y L S +N+L F P N
Sbjct 184 CEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLH-SAAVNALSFHPSGN 242
Query 269 YWLCAATDKSVKIWDLENKNVLDDIHPDQ 297
Y + A++D ++KI DL +L +H Q
Sbjct 243 YLITASSDSTLKILDLMEGRLLYTLHGHQ 271
Score = 75.1 bits (183), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 80/285 (28%), Positives = 117/285 (41%), Gaps = 65/285 (22%)
Query 10 FALSASAKMSVSVDSPLVF--------KGVLEGHTDWVTAIS-TPTVKSNTIISSSRDKK 60
F+L+ S S+DS L+ GH D VT ++ +P+ + + S SRDK
Sbjct 27 FSLNTKHLASGSMDSTLMIWHMKPQSRAYRFTGHKDAVTCVNFSPS--GHLLASGSRDKT 84
Query 61 IIVWNLNDSPNAETVGFARRALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGET 120
+ +W PN + RA H+ V+ V SD ++ S DKT+++W +
Sbjct 85 VRIW----VPNVKGESTVFRA---HTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRF 137
Query 121 VRTFQKHTSDVNSVAFSADNRQIVSGSRDRTVRLWN-TLADCKYTIEEGQHTDWVSCVRF 179
+ + +H + V FS D R IVS S D+TV+LW+ T +C ++ E H +V+ V F
Sbjct 138 LFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCE--HGGFVTYVDF 195
Query 180 SPSPKEPLIVSCGWDKLVKVWSLTTCKLTTN----------------------------- 210
PS I + G D VKVW T +L +
Sbjct 196 HPSGT--CIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTL 253
Query 211 -------------LVGHTSVLYTVTVSPDGSLCASGGKDGVAMLW 242
L GH TV S G ASGG D M+W
Sbjct 254 KILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
Score = 43.1 bits (100), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 0/76 (0%)
Query 85 HSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIV 144
HS V + N+ ++ S D TL++ DL G + T H +VAFS
Sbjct 228 HSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFA 287
Query 145 SGSRDRTVRLWNTLAD 160
SG D V +W + D
Sbjct 288 SGGSDEQVMVWKSNFD 303
Score = 34.7 bits (78), Expect = 0.57, Method: Compositional matrix adjust.
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 8/81 (9%)
Query 207 LTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSL----DASCTINSL 262
L + GH + V S + ASG D M+W + Y DA +N
Sbjct 11 LERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKPQSRAYRFTGHKDAVTCVN-- 68
Query 263 CFSPCNYWLCAAT-DKSVKIW 282
FSP + L + + DK+V+IW
Sbjct 69 -FSPSGHLLASGSRDKTVRIW 88
> xla:734519 poc1b, MGC114911, pix1, tuwd12, wdr51b; POC1 centriolar
protein homolog B (Chlamydomonas)
Length=468
Score = 129 bits (324), Expect = 1e-29, Method: Compositional matrix adjust.
Identities = 95/317 (29%), Positives = 150/317 (47%), Gaps = 22/317 (6%)
Query 18 MSVSVDSPLVFKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGF 77
M+ ++D P + + +GH D VT + + S + SSS D +++WN P + +
Sbjct 1 MASALDDPALQRH-FKGHKDAVTCVDF-SPDSKQLASSSADACVMIWNFK--PQSRAYKY 56
Query 78 ARRALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFS 137
GH + V V S + S S D+T+RLW N+ + HT+ V V FS
Sbjct 57 P-----GHKEAVTCVQFSPSGHLVASSSKDRTVRLWAPNIKGESTVLKAHTAVVRCVNFS 111
Query 138 ADNRQIVSGSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLV 197
+D + ++ S D++++ WN L ++ QHT+WV C RFSP + LI SC DK V
Sbjct 112 SDGQTFITASDDKSIKAWN-LHRQRFLFSLTQHTNWVRCARFSPDGR--LIASCSDDKTV 168
Query 198 KVWSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDA-S 256
++W LT V + V + G+ AS G D +WD+ K L +
Sbjct 169 RIWDLTNRLCINTFVDYKGHSNYVDFNQMGTCVASAGADSTVKVWDIRMNKLLQHYQVHN 228
Query 257 CTINSLCFSPC-NYWLCAATDKSVKIWDLENKNVLDDIHPDQ-PVKSGIPWCTSLNWSYD 314
++SL F P NY L A++D ++KI DL ++ +H Q PV S+ +S
Sbjct 229 AGVSSLSFHPSGNYLLTASSDGTLKILDLLEGRLIYTLHGHQGPV-------LSVTFSKS 281
Query 315 GRTLFIGTTSGNIHVYE 331
G G T + V++
Sbjct 282 GDQFASGATDAQVLVWK 298
Score = 74.7 bits (182), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 64/219 (29%), Positives = 98/219 (44%), Gaps = 11/219 (5%)
Query 31 VLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQ 90
VL+ HT V ++ + T I++S DK I WNL+ + F+ LT H+ V+
Sbjct 97 VLKAHTAVVRCVNF-SSDGQTFITASDDKSIKAWNLH----RQRFLFS---LTQHTNWVR 148
Query 91 DVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDR 150
S D S S DKT+R+WDL + TF + N V F+ + S D
Sbjct 149 CARFSPDGRLIASCSDDKTVRIWDLTNRLCINTFVDYKGHSNYVDFNQMGTCVASAGADS 208
Query 151 TVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTN 210
TV++W+ + K H VS + F PS +++ D +K+ L +L
Sbjct 209 TVKVWDIRMN-KLLQHYQVHNAGVSSLSFHPSGN--YLLTASSDGTLKILDLLEGRLIYT 265
Query 211 LVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKH 249
L GH + +VT S G ASG D ++W + K+
Sbjct 266 LHGHQGPVLSVTFSKSGDQFASGATDAQVLVWKTNFDKY 304
Score = 48.9 bits (115), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
Query 85 HSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIV 144
H+ V + N+ L+ S D TL++ DL G + T H V SV FS Q
Sbjct 227 HNAGVSSLSFHPSGNYLLTASSDGTLKILDLLEGRLIYTLHGHQGPVLSVTFSKSGDQFA 286
Query 145 SGSRDRTVRLWNTLADCKYTIEE 167
SG+ D V +W T D KY+++E
Sbjct 287 SGATDAQVLVWKTNFD-KYSVKE 308
> mmu:382406 Poc1b, 4933430F16Rik, Wdr51b; POC1 centriolar protein
homolog B (Chlamydomonas)
Length=476
Score = 128 bits (321), Expect = 3e-29, Method: Compositional matrix adjust.
Identities = 84/270 (31%), Positives = 136/270 (50%), Gaps = 16/270 (5%)
Query 18 MSVSVDSPLVFKGVLEGHTDWVTAIS-TPTVKSNTIISSSRDKKIIVWNLNDSPNAETVG 76
M+ ++ P++ + +GH +T+ +P K I ++S D +++W+L P+A
Sbjct 1 MASGLEDPILERS-FKGHKAAITSADFSPNCKQ--IATASWDTFLMLWSLK--PHARAYR 55
Query 77 FARRALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAF 136
+ GH V + S N S S D+T+RLW L+ F+ HT+ V SV F
Sbjct 56 YV-----GHKDVVTSLQFSPQGNLLASASRDRTVRLWVLDRKGKSSEFKAHTAPVRSVDF 110
Query 137 SADNRQIVSGSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKL 196
SAD + +V+ S D+++++W+ ++ +HT WV C +FSP + LIVSC DK
Sbjct 111 SADGQLLVTASEDKSIKVWSMFRQ-RFLYSLYRHTHWVRCAKFSPDGR--LIVSCSEDKT 167
Query 197 VKVWSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDA- 255
+K+W T + N V +P+G+ AS G D +WD+ K L
Sbjct 168 IKIWDTTNKQCVNNFSDSVGFANFVDFNPNGTCIASAGSDHAVKIWDIRMNKLLQHYQVH 227
Query 256 SCTINSLCFSPC-NYWLCAATDKSVKIWDL 284
SC +N L F P N + A++D +VK+ DL
Sbjct 228 SCGVNCLSFHPLGNSLVTASSDGTVKMLDL 257
Score = 92.4 bits (228), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 74/258 (28%), Positives = 115/258 (44%), Gaps = 11/258 (4%)
Query 80 RALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSAD 139
R+ GH + S + + SWD L LW L + H V S+ FS
Sbjct 12 RSFKGHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHARAYRYVGHKDVVTSLQFSPQ 71
Query 140 NRQIVSGSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKV 199
+ S SRDRTVRLW L + E HT V V FS + L+V+ DK +KV
Sbjct 72 GNLLASASRDRTVRLW-VLDRKGKSSEFKAHTAPVRSVDFSADGQ--LLVTASEDKSIKV 128
Query 200 WSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSL-DASCT 258
WS+ + +L HT + SPDG L S +D +WD + + + + D+
Sbjct 129 WSMFRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGF 188
Query 259 INSLCFSPCNYWLCAA-TDKSVKIWDLENKNVLDDIHPDQPVKSGIPWCTSLNWSYDGRT 317
N + F+P + +A +D +VKIWD+ +L Q G+ L++ G +
Sbjct 189 ANFVDFNPNGTCIASAGSDHAVKIWDIRMNKLLQHY---QVHSCGV---NCLSFHPLGNS 242
Query 318 LFIGTTSGNIHVYEVAEG 335
L ++ G + + ++ EG
Sbjct 243 LVTASSDGTVKMLDLIEG 260
Score = 84.7 bits (208), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 70/279 (25%), Positives = 115/279 (41%), Gaps = 52/279 (18%)
Query 34 GHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQDVV 93
GH D VT++ + + N + S+SRD+ + +W L+ + H+ V+ V
Sbjct 58 GHKDVVTSLQF-SPQGNLLASASRDRTVRLWVLDRKGKSS-------EFKAHTAPVRSVD 109
Query 94 ISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRTVR 153
S+D ++ S DK++++W + + + +HT V FS D R IVS S D+T++
Sbjct 110 FSADGQLLVTASEDKSIKVWSMFRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIK 169
Query 154 LW--------NTLADC---------------------------------KYTIEEGQHTD 172
+W N +D K H+
Sbjct 170 IWDTTNKQCVNNFSDSVGFANFVDFNPNGTCIASAGSDHAVKIWDIRMNKLLQHYQVHSC 229
Query 173 WVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCAS 232
V+C+ F P +V+ D VK+ L +L L GHT ++TV+ S DG L S
Sbjct 230 GVNCLSFHPLGNS--LVTASSDGTVKMLDLIEGRLIYTLQGHTGPVFTVSFSKDGELLTS 287
Query 233 GGKDGVAMLWDVSEGKHLYSLDASCTINSLCFSPCNYWL 271
GG D ++W + HL+ D + L F + L
Sbjct 288 GGADAQVLIWR-TNFIHLHCKDPKRNLKRLHFEASPHLL 325
> dre:406322 poc1a, wdr51a, wu:fl82d01, zgc:56055; POC1 centriolar
protein homolog A (Chlamydomonas)
Length=416
Score = 124 bits (310), Expect = 6e-28, Method: Compositional matrix adjust.
Identities = 96/301 (31%), Positives = 149/301 (49%), Gaps = 22/301 (7%)
Query 18 MSVSVDSPLVFKGVLEGHTDWVTAIS-TPTVKSNTIISSSRDKKIIVWNLNDSPNAETVG 76
MS ++D P + + +GH D +T++ +P+ K I S S D ++VWN+ P +
Sbjct 1 MSSALDDPTLERN-FKGHRDAITSLDFSPSGKQ--IASGSVDASVMVWNMK--PQSRAYR 55
Query 77 FARRALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNV-GETVRTFQKHTSDVNSVA 135
F TGH V V S ++ S S DKT+RLW +V GE+V F+ HT V SV
Sbjct 56 F-----TGHKDAVTCVQFSPSAHLLASSSRDKTVRLWVPSVKGESV-LFRAHTGSVRSVC 109
Query 136 FSADNRQIVSGSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDK 195
FSAD + +++ S D++++LW ++ K +H +WV C RFSP + L+VS D+
Sbjct 110 FSADGQSLLTASDDQSIKLW-SVHRQKIICTLREHNNWVRCARFSPDGQ--LMVSVSDDR 166
Query 196 LVKVWSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDA 255
VK+W ++ +L V P + A+ D +WD+ L
Sbjct 167 TVKLWDASSRQLIHTFCEPGGYSSYVDFHPSSTCIATASSDNTVRVWDIRTHTLLQHYQV 226
Query 256 -SCTINSLCFSPC-NYWLCAATDKSVKIWDLENKNVLDDIHPDQPVKSGIPWCTSLNWSY 313
S +N+L F P N+ L A++D ++KI DL +L +H Q G C S + S
Sbjct 227 HSAAVNALSFHPSGNHLLTASSDSTLKILDLLEGRLLYTLHGHQ----GSASCVSFSRSG 282
Query 314 D 314
D
Sbjct 283 D 283
Score = 66.6 bits (161), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 72/253 (28%), Positives = 108/253 (42%), Gaps = 57/253 (22%)
Query 34 GHTDWVTAIS-TPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQDV 92
GH D VT + +P+ ++ + SSSRDK + +W S E+V F RA TG V+ V
Sbjct 58 GHKDAVTCVQFSPS--AHLLASSSRDKTVRLWV--PSVKGESVLF--RAHTG---SVRSV 108
Query 93 VISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRTV 152
S+D L+ S D++++LW ++ + + T ++H + V FS D + +VS S DRTV
Sbjct 109 CFSADGQSLLTASDDQSIKLWSVHRQKIICTLREHNNWVRCARFSPDGQLMVSVSDDRTV 168
Query 153 RLWNTLADCKYTI----EEGQ--------------------------------------- 169
+LW+ A + I E G
Sbjct 169 KLWD--ASSRQLIHTFCEPGGYSSYVDFHPSSTCIATASSDNTVRVWDIRTHTLLQHYQV 226
Query 170 HTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTVSPDGSL 229
H+ V+ + F PS L S D +K+ L +L L GH V+ S G
Sbjct 227 HSAAVNALSFHPSGNHLLTASS--DSTLKILDLLEGRLLYTLHGHQGSASCVSFSRSGDQ 284
Query 230 CASGGKDGVAMLW 242
AS G D M+W
Sbjct 285 FASAGSDQQVMVW 297
Score = 40.4 bits (93), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 29/109 (26%), Positives = 44/109 (40%), Gaps = 7/109 (6%)
Query 49 SNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQDVVISSDSNFALSGSWDK 108
S I ++S D + VW++ + HS V + N L+ S D
Sbjct 198 STCIATASSDNTVRVWDIRTHTLLQHYQV-------HSAAVNALSFHPSGNHLLTASSDS 250
Query 109 TLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRTVRLWNT 157
TL++ DL G + T H + V+FS Q S D+ V +W T
Sbjct 251 TLKILDLLEGRLLYTLHGHQGSASCVSFSRSGDQFASAGSDQQVMVWRT 299
> dre:386932 poc1b, TUWD12, fl36w17, wdr51b, wu:fl36w17, zgc:63538;
POC1 centriolar protein homolog B (Chlamydomonas)
Length=490
Score = 120 bits (302), Expect = 5e-27, Method: Compositional matrix adjust.
Identities = 78/266 (29%), Positives = 132/266 (49%), Gaps = 15/266 (5%)
Query 32 LEGHTDWVT-AISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQ 90
+GH D ++ A P K + + S DK +++WNL +P A F GH+ +
Sbjct 14 FKGHKDVISCADFNPNNKQ--LATGSCDKSLMIWNL--APKARAFRFV-----GHTDVIT 64
Query 91 DVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDR 150
V + + S S D+T+RLW ++ F+ HT+ V SV FS D +++V+ S D+
Sbjct 65 GVNFAPSGSLVASSSRDQTVRLWTPSIKGESTVFKAHTASVRSVNFSRDGQRLVTASDDK 124
Query 151 TVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTN 210
+V++W + K+ +HT+WV C RFSP + LI SCG D+ V++W ++ + T
Sbjct 125 SVKVWG-VERKKFLYSLNRHTNWVRCARFSPDGR--LIASCGDDRTVRLWDTSSHQCTNI 181
Query 211 LVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDA-SCTINSLCFSPC-N 268
+ V + G+ AS G D +WD+ K + + +N F P N
Sbjct 182 FTDYGGSATFVDFNSSGTCIASSGADNTIKIWDIRTNKLIQHYKVHNAGVNCFSFHPSGN 241
Query 269 YWLCAATDKSVKIWDLENKNVLDDIH 294
Y + ++D ++KI DL ++ +H
Sbjct 242 YLISGSSDSTIKILDLLEGRLIYTLH 267
Score = 80.5 bits (197), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 69/250 (27%), Positives = 102/250 (40%), Gaps = 51/250 (20%)
Query 34 GHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQDVV 93
GHTD +T ++ S + SSSRD+ + +W S E+ F H+ V+ V
Sbjct 58 GHTDVITGVNFAPSGS-LVASSSRDQTVRLWT--PSIKGESTVFK-----AHTASVRSVN 109
Query 94 ISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRTVR 153
S D ++ S DK++++W + + + + +HT+ V FS D R I S DRTVR
Sbjct 110 FSRDGQRLVTASDDKSVKVWGVERKKFLYSLNRHTNWVRCARFSPDGRLIASCGDDRTVR 169
Query 154 LWNT-----------------------------------------LADCKYTIEEGQHTD 172
LW+T + K H
Sbjct 170 LWDTSSHQCTNIFTDYGGSATFVDFNSSGTCIASSGADNTIKIWDIRTNKLIQHYKVHNA 229
Query 173 WVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCAS 232
V+C F PS ++S D +K+ L +L L GH + TVT S DG L AS
Sbjct 230 GVNCFSFHPSGN--YLISGSSDSTIKILDLLEGRLIYTLHGHKGPVLTVTFSRDGDLFAS 287
Query 233 GGKDGVAMLW 242
GG D ++W
Sbjct 288 GGADSQVLMW 297
Score = 43.1 bits (100), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 37/138 (26%), Positives = 55/138 (39%), Gaps = 13/138 (9%)
Query 52 IISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQDVVISSDSNFALSGSWDKTLR 111
I SS D I +W++ + + H+ V N+ +SGS D T++
Sbjct 201 IASSGADNTIKIWDIRTNKLIQHYKV-------HNAGVNCFSFHPSGNYLISGSSDSTIK 253
Query 112 LWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRTVRLWNTLAD-CKYTIEEGQH 170
+ DL G + T H V +V FS D SG D V +W T D Y +H
Sbjct 254 ILDLLEGRLIYTLHGHKGPVLTVTFSRDGDLFASGGADSQVLMWKTNFDSLNYRELLSRH 313
Query 171 TDWVSCVRFSPSPKEPLI 188
+ R +P P L+
Sbjct 314 SK-----RVTPDPPPHLM 326
Score = 32.0 bits (71), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 26/130 (20%), Positives = 57/130 (43%), Gaps = 8/130 (6%)
Query 207 LTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVS-EGKHLYSLDASCTINSLCFS 265
L + GH V+ +P+ A+G D M+W+++ + + + + I + F+
Sbjct 10 LERHFKGHKDVISCADFNPNNKQLATGSCDKSLMIWNLAPKARAFRFVGHTDVITGVNFA 69
Query 266 PCNYWLCAAT-DKSVKIWDLENKNVLDDIHPDQPVKSGIPWCTSLNWSYDGRTLFIGTTS 324
P + +++ D++V++W K K+ S+N+S DG+ L +
Sbjct 70 PSGSLVASSSRDQTVRLWTPSIKG------ESTVFKAHTASVRSVNFSRDGQRLVTASDD 123
Query 325 GNIHVYEVAE 334
++ V+ V
Sbjct 124 KSVKVWGVER 133
> xla:379573 poc1a, MGC69111, pix2, wdr51a; POC1 centriolar protein
homolog A (Chlamydomonas)
Length=399
Score = 120 bits (300), Expect = 8e-27, Method: Compositional matrix adjust.
Identities = 77/241 (31%), Positives = 116/241 (48%), Gaps = 13/241 (5%)
Query 62 IVWNLNDSPNAETVGFARRALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETV 121
+VWN+ A GH + V S + S S DKT+RLW +V
Sbjct 1 MVWNMKTQMRA-------YRFVGHKDAILSVDFSPSGHLIASASRDKTVRLWVPSVKGES 53
Query 122 RTFQKHTSDVNSVAFSADNRQIVSGSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSP 181
F+ HT V SV+FS D + +V+ S D+T+++W T+ K+ QH +WV C +FSP
Sbjct 54 TAFKAHTGTVRSVSFSGDGQSLVTASDDKTIKVW-TVHRQKFLFSLNQHINWVRCAKFSP 112
Query 182 SPKEPLIVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAML 241
+ LIVS DK +K+W T+ + + H + V P G+ A+ D +
Sbjct 113 DGR--LIVSASDDKTIKLWDKTSRECIQSFCEHGGFVNFVDFHPSGTCIAAAATDNTVKV 170
Query 242 WDVSEGKHLYSLDA-SCTINSLCFSPC-NYWLCAATDKSVKIWDLENKNVLDDIHPDQ-P 298
WD+ K + S +NSL F P NY + A+ D ++K+ DL +L +H Q P
Sbjct 171 WDIRMNKLIQHYQVHSGVVNSLSFHPSGNYLITASNDSTLKVLDLLEGRLLYTLHGHQGP 230
Query 299 V 299
V
Sbjct 231 V 231
Score = 80.1 bits (196), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 65/226 (28%), Positives = 100/226 (44%), Gaps = 11/226 (4%)
Query 112 LWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRTVRLWNTLADCKYTIEEGQHT 171
+W++ F H + SV FS I S SRD+TVRLW + T + HT
Sbjct 2 VWNMKTQMRAYRFVGHKDAILSVDFSPSGHLIASASRDKTVRLWVPSVKGESTAFKA-HT 60
Query 172 DWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCA 231
V V FS + +V+ DK +KVW++ K +L H + + SPDG L
Sbjct 61 GTVRSVSFSGDGQS--LVTASDDKTIKVWTVHRQKFLFSLNQHINWVRCAKFSPDGRLIV 118
Query 232 SGGKDGVAMLWDVSEGKHLYSL-DASCTINSLCFSPCNYWLCAA-TDKSVKIWDLENKNV 289
S D LWD + + + S + +N + F P + AA TD +VK+WD+ +
Sbjct 119 SASDDKTIKLWDKTSRECIQSFCEHGGFVNFVDFHPSGTCIAAAATDNTVKVWDIRMNKL 178
Query 290 LDDIHPDQPVKSGIPWCTSLNWSYDGRTLFIGTTSGNIHVYEVAEG 335
+ V SG+ SL++ G L + + V ++ EG
Sbjct 179 IQHYQ----VHSGV--VNSLSFHPSGNYLITASNDSTLKVLDLLEG 218
Score = 74.3 bits (181), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 60/211 (28%), Positives = 98/211 (46%), Gaps = 11/211 (5%)
Query 32 LEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQD 91
+ HT V ++S + +++++S DK I VW ++ + F+ L H V+
Sbjct 56 FKAHTGTVRSVSF-SGDGQSLVTASDDKTIKVWTVH----RQKFLFS---LNQHINWVRC 107
Query 92 VVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRT 151
S D +S S DKT++LWD E +++F +H VN V F I + + D T
Sbjct 108 AKFSPDGRLIVSASDDKTIKLWDKTSRECIQSFCEHGGFVNFVDFHPSGTCIAAAATDNT 167
Query 152 VRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTNL 211
V++W+ + K H+ V+ + F PS +++ D +KV L +L L
Sbjct 168 VKVWDIRMN-KLIQHYQVHSGVVNSLSFHPSGN--YLITASNDSTLKVLDLLEGRLLYTL 224
Query 212 VGHTSVLYTVTVSPDGSLCASGGKDGVAMLW 242
GH + V S +G ASGG D M+W
Sbjct 225 HGHQGPVTCVKFSREGDFFASGGSDEQVMVW 255
> hsa:282809 POC1B, FLJ14923, FLJ41111, PIX1, TUWD12, WDR51B;
POC1 centriolar protein homolog B (Chlamydomonas)
Length=436
Score = 116 bits (291), Expect = 1e-25, Method: Compositional matrix adjust.
Identities = 73/225 (32%), Positives = 110/225 (48%), Gaps = 12/225 (5%)
Query 62 IVWNLNDSPNAETVGFARRALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETV 121
++WN P+A + GH V V S N S S D+T+RLW +
Sbjct 1 MLWNFK--PHARAYRYV-----GHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKF 53
Query 122 RTFQKHTSDVNSVAFSADNRQIVSGSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSP 181
F+ HT+ V SV FSAD + + + S D+++++W ++ ++ +HT WV C +FSP
Sbjct 54 SEFKAHTAPVRSVDFSADGQFLATASEDKSIKVW-SMYRQRFLYSLYRHTHWVRCAKFSP 112
Query 182 SPKEPLIVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAML 241
+ LIVSC DK +K+W T + N V +P G+ AS G D +
Sbjct 113 DGR--LIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKV 170
Query 242 WDVSEGKHLYSLDA-SCTINSLCFSPC-NYWLCAATDKSVKIWDL 284
WDV K L S +N + F P NY + A++D ++KI DL
Sbjct 171 WDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDL 215
Score = 89.4 bits (220), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 70/264 (26%), Positives = 124/264 (46%), Gaps = 19/264 (7%)
Query 34 GHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQDVV 93
GH D VT++ + N + S+SRD+ + +W P+ F+ H+ V+ V
Sbjct 16 GHKDVVTSVQF-SPHGNLLASASRDRTVRLW----IPDKRG-KFSE--FKAHTAPVRSVD 67
Query 94 ISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRTVR 153
S+D F + S DK++++W + + + +HT V FS D R IVS S D+T++
Sbjct 68 FSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIK 127
Query 154 LWNTL-ADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTNLV 212
+W+T C + + + V F+PS I S G D+ VKVW + KL +
Sbjct 128 IWDTTNKQCVNNFSDS--VGFANFVDFNPSGT--CIASAGSDQTVKVWDVRVNKLLQHYQ 183
Query 213 GHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDA-SCTINSLCFSP-CNYW 270
H+ + ++ P G+ + DG + D+ EG+ +Y+L + + ++ FS +
Sbjct 184 VHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELF 243
Query 271 LCAATDKSVKIWDLENKNVLDDIH 294
D V +W + D++H
Sbjct 244 ASGGADTQVLLW----RTNFDELH 263
Score = 83.2 bits (204), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 66/226 (29%), Positives = 103/226 (45%), Gaps = 11/226 (4%)
Query 112 LWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRTVRLWNTLADCKYTIEEGQHT 171
LW+ + H V SV FS + S SRDRTVRLW K++ E HT
Sbjct 2 LWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFS-EFKAHT 60
Query 172 DWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCA 231
V V FS + + + DK +KVWS+ + +L HT + SPDG L
Sbjct 61 APVRSVDFSADGQ--FLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIV 118
Query 232 SGGKDGVAMLWDVSEGKHLYSL-DASCTINSLCFSPCNYWLCAA-TDKSVKIWDLENKNV 289
S +D +WD + + + + D+ N + F+P + +A +D++VK+WD+ +
Sbjct 119 SCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKL 178
Query 290 LDDIHPDQPVKSGIPWCTSLNWSYDGRTLFIGTTSGNIHVYEVAEG 335
L V SG C S + S G L ++ G + + ++ EG
Sbjct 179 LQHYQ----VHSGGVNCISFHPS--GNYLITASSDGTLKILDLLEG 218
> xla:399199 pafah1b1, lis2, mdcr, mds, pafah, pafah1b1-b; platelet-activating
factor acetylhydrolase 1b, regulatory subunit
1 (45kDa) (EC:3.1.1.47); K01062 1-alkyl-2-acetylglycerophosphocholine
esterase [EC:3.1.1.47]
Length=410
Score = 115 bits (289), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 94/326 (28%), Positives = 145/326 (44%), Gaps = 41/326 (12%)
Query 29 KGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQC 88
K L GH VT + V S ++++S D I VW+ ET F R L GH+
Sbjct 101 KYALSGHRSPVTRVIFHPVFS-VMVTASEDATIKVWDY------ETGDF-ERTLKGHTDS 152
Query 89 VQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSR 148
VQD+ S S D T++LWD E +RT H +V+SVA + IVS SR
Sbjct 153 VQDISFDHSGKLLASCSADMTIKLWDFQGFECLRTMHGHDHNVSSVAIMPNGDHIVSASR 212
Query 149 DRTVRLWNTLAD-CKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKL 207
D+T+++W C T H +WV VR P+ LI SC D+ V+VW + T +
Sbjct 213 DKTIKMWEVQTGYCVKTF--TGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKEC 268
Query 208 TTNLVGHTSVLYTVTVSPD--------------------GSLCASGGKDGVAMLWDVSEG 247
L H V+ ++ +P+ G SG +D +WD+S G
Sbjct 269 KAELREHEHVVECISWAPESSYSTISDATGSETKRSGKPGPFLLSGSRDKTIKMWDISIG 328
Query 248 KHLYSLDASCT-INSLCFSP-CNYWLCAATDKSVKIWDLENKNVLDDIHPDQPVKSGIPW 305
L +L + + F P + L A DK+++IWD +NK + ++ + +
Sbjct 329 MCLMTLVGHDNWVRGVQFHPGGKFILSCADDKTIRIWDYKNKRCMKTLNAHE------HF 382
Query 306 CTSLNWSYDGRTLFIGTTSGNIHVYE 331
TSL++ + G+ + V+E
Sbjct 383 VTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 99.4 bits (246), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 78/278 (28%), Positives = 122/278 (43%), Gaps = 33/278 (11%)
Query 28 FKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFA-RRALTGHS 86
F+ L+GHTD V IS + S S D I +W+ GF R + GH
Sbjct 142 FERTLKGHTDSVQDISFDH-SGKLLASCSADMTIKLWDFQ--------GFECLRTMHGHD 192
Query 87 QCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSG 146
V V I + + +S S DKT+++W++ G V+TF H V V + D I S
Sbjct 193 HNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASC 252
Query 147 SRDRTVRLW-NTLADCKYTIEEGQHTDWVSCVRFSPS------------------PKEPL 187
S D+TVR+W +CK + E +H V C+ ++P P
Sbjct 253 SNDQTVRVWVVATKECKAELREHEHV--VECISWAPESSYSTISDATGSETKRSGKPGPF 310
Query 188 IVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEG 247
++S DK +K+W ++ LVGH + + V P G S D +WD
Sbjct 311 LLSGSRDKTIKMWDISIGMCLMTLVGHDNWVRGVQFHPGGKFILSCADDKTIRIWDYKNK 370
Query 248 KHLYSLDA-SCTINSLCFSP-CNYWLCAATDKSVKIWD 283
+ + +L+A + SL F Y + + D++VK+W+
Sbjct 371 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
> mmu:18472 Pafah1b1, LIS-1, Lis1, MGC25297, MMS10-U, Mdsh, Ms10u,
Pafaha; platelet-activating factor acetylhydrolase, isoform
1b, subunit 1 (EC:3.1.1.47); K01062 1-alkyl-2-acetylglycerophosphocholine
esterase [EC:3.1.1.47]
Length=410
Score = 115 bits (288), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 95/326 (29%), Positives = 145/326 (44%), Gaps = 41/326 (12%)
Query 29 KGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQC 88
K L GH VT + V S ++S+S D I VW+ ET F R L GH+
Sbjct 101 KYALSGHRSPVTRVIFHPVFS-VMVSASEDATIKVWDY------ETGDF-ERTLKGHTDS 152
Query 89 VQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSR 148
VQD+ S S D T++LWD E +RT H +V+SVA + IVS SR
Sbjct 153 VQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASR 212
Query 149 DRTVRLWNTLAD-CKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKL 207
D+T+++W C T H +WV VR P+ LI SC D+ V+VW + T +
Sbjct 213 DKTIKMWEVQTGYCVKTF--TGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKEC 268
Query 208 TTNLVGHTSVLYTVTVSPD--------------------GSLCASGGKDGVAMLWDVSEG 247
L H V+ ++ +P+ G SG +D +WDVS G
Sbjct 269 KAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTG 328
Query 248 KHLYSLDASCT-INSLCF-SPCNYWLCAATDKSVKIWDLENKNVLDDIHPDQPVKSGIPW 305
L +L + + F S + L A DK++++WD +NK + ++ + +
Sbjct 329 MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHE------HF 382
Query 306 CTSLNWSYDGRTLFIGTTSGNIHVYE 331
TSL++ + G+ + V+E
Sbjct 383 VTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 95.9 bits (237), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 78/278 (28%), Positives = 122/278 (43%), Gaps = 33/278 (11%)
Query 28 FKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFA-RRALTGHS 86
F+ L+GHTD V IS + S S D I +W+ GF R + GH
Sbjct 142 FERTLKGHTDSVQDISFDH-SGKLLASCSADMTIKLWDFQ--------GFECIRTMHGHD 192
Query 87 QCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSG 146
V V I + + +S S DKT+++W++ G V+TF H V V + D I S
Sbjct 193 HNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASC 252
Query 147 SRDRTVRLW-NTLADCKYTIEEGQHTDWVSCVRFSPS------------------PKEPL 187
S D+TVR+W +CK + E +H V C+ ++P P
Sbjct 253 SNDQTVRVWVVATKECKAELREHEHV--VECISWAPESSYSSISEATGSETKKSGKPGPF 310
Query 188 IVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEG 247
++S DK +K+W ++T LVGH + + V G S D +WD
Sbjct 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
Query 248 KHLYSLDA-SCTINSLCFSP-CNYWLCAATDKSVKIWD 283
+ + +L+A + SL F Y + + D++VK+W+
Sbjct 371 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
> hsa:5048 PAFAH1B1, LIS1, LIS2, MDCR, MDS, PAFAH; platelet-activating
factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
(EC:3.1.1.47); K01062 1-alkyl-2-acetylglycerophosphocholine
esterase [EC:3.1.1.47]
Length=410
Score = 115 bits (288), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 95/326 (29%), Positives = 145/326 (44%), Gaps = 41/326 (12%)
Query 29 KGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQC 88
K L GH VT + V S ++S+S D I VW+ ET F R L GH+
Sbjct 101 KYALSGHRSPVTRVIFHPVFS-VMVSASEDATIKVWDY------ETGDF-ERTLKGHTDS 152
Query 89 VQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSR 148
VQD+ S S D T++LWD E +RT H +V+SVA + IVS SR
Sbjct 153 VQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASR 212
Query 149 DRTVRLWNTLAD-CKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKL 207
D+T+++W C T H +WV VR P+ LI SC D+ V+VW + T +
Sbjct 213 DKTIKMWEVQTGYCVKTF--TGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKEC 268
Query 208 TTNLVGHTSVLYTVTVSPD--------------------GSLCASGGKDGVAMLWDVSEG 247
L H V+ ++ +P+ G SG +D +WDVS G
Sbjct 269 KAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTG 328
Query 248 KHLYSLDASCT-INSLCF-SPCNYWLCAATDKSVKIWDLENKNVLDDIHPDQPVKSGIPW 305
L +L + + F S + L A DK++++WD +NK + ++ + +
Sbjct 329 MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHE------HF 382
Query 306 CTSLNWSYDGRTLFIGTTSGNIHVYE 331
TSL++ + G+ + V+E
Sbjct 383 VTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 95.9 bits (237), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 78/278 (28%), Positives = 122/278 (43%), Gaps = 33/278 (11%)
Query 28 FKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFA-RRALTGHS 86
F+ L+GHTD V IS + S S D I +W+ GF R + GH
Sbjct 142 FERTLKGHTDSVQDISFDH-SGKLLASCSADMTIKLWDFQ--------GFECIRTMHGHD 192
Query 87 QCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSG 146
V V I + + +S S DKT+++W++ G V+TF H V V + D I S
Sbjct 193 HNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASC 252
Query 147 SRDRTVRLW-NTLADCKYTIEEGQHTDWVSCVRFSPS------------------PKEPL 187
S D+TVR+W +CK + E +H V C+ ++P P
Sbjct 253 SNDQTVRVWVVATKECKAELREHEHV--VECISWAPESSYSSISEATGSETKKSGKPGPF 310
Query 188 IVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEG 247
++S DK +K+W ++T LVGH + + V G S D +WD
Sbjct 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
Query 248 KHLYSLDA-SCTINSLCFSP-CNYWLCAATDKSVKIWD 283
+ + +L+A + SL F Y + + D++VK+W+
Sbjct 371 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
> dre:394247 pafah1b1b, Lis1a; platelet-activating factor acetylhydrolase,
isoform Ib, alpha subunit b; K01062 1-alkyl-2-acetylglycerophosphocholine
esterase [EC:3.1.1.47]
Length=410
Score = 114 bits (285), Expect = 6e-25, Method: Compositional matrix adjust.
Identities = 91/326 (27%), Positives = 143/326 (43%), Gaps = 41/326 (12%)
Query 29 KGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQC 88
K L GH VT + V S ++S+S D I VW+ G R L GH+
Sbjct 101 KYALSGHRSPVTRVIFHPVFS-LMVSASEDATIKVWDYE-------AGDFERTLKGHTDS 152
Query 89 VQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSR 148
VQD+ S S D T++LWD E +RT H +V+SVA + IVS SR
Sbjct 153 VQDISFDQTGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASR 212
Query 149 DRTVRLWNTLAD-CKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKL 207
D+T+++W C T H +WV VR P+ L+ SC D+ V+VW + T +
Sbjct 213 DKTMKMWEVATGYCVKTFT--GHREWVRMVR--PNQDGTLLASCSNDQTVRVWVVATKEC 268
Query 208 TTNLVGHTSVLYTVTVSPD--------------------GSLCASGGKDGVAMLWDVSEG 247
L H V+ ++ +P+ G SG +D +WD+S G
Sbjct 269 KAELREHEHVVECISWAPESAHPTISEATGSENKKSGKPGPFLLSGSRDKTIKMWDISTG 328
Query 248 KHLYSLDASCT-INSLCFSPCNYWLCA-ATDKSVKIWDLENKNVLDDIHPDQPVKSGIPW 305
L +L + + F P ++ + A DK+++IWD +NK + + + +
Sbjct 329 MCLMTLVGHDNWVRGVLFHPGGRFVVSCADDKTLRIWDYKNKRCMKTLSAHE------HF 382
Query 306 CTSLNWSYDGRTLFIGTTSGNIHVYE 331
TSL++ + G+ + V+E
Sbjct 383 VTSLDFHKASPYVVTGSVDQTVKVWE 408
Score = 100 bits (250), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 85/305 (27%), Positives = 133/305 (43%), Gaps = 38/305 (12%)
Query 6 VFH-CFALSASAKMSVSVD----SPLVFKGVLEGHTDWVTAISTPTVKSNTIISSSRDKK 60
+FH F+L SA ++ F+ L+GHTD V IS + S S D
Sbjct 115 IFHPVFSLMVSASEDATIKVWDYEAGDFERTLKGHTDSVQDISFDQT-GKLLASCSADMT 173
Query 61 IIVWNLNDSPNAETVGFA-RRALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGE 119
I +W+ GF R + GH V V I + + +S S DKT+++W++ G
Sbjct 174 IKLWDFQ--------GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTMKMWEVATGY 225
Query 120 TVRTFQKHTSDVNSVAFSADNRQIVSGSRDRTVRLW-NTLADCKYTIEEGQHTDWVSCVR 178
V+TF H V V + D + S S D+TVR+W +CK + E +H V C+
Sbjct 226 CVKTFTGHREWVRMVRPNQDGTLLASCSNDQTVRVWVVATKECKAELREHEHV--VECIS 283
Query 179 FSPSPKEPLI------------------VSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYT 220
++P P I +S DK +K+W ++T LVGH + +
Sbjct 284 WAPESAHPTISEATGSENKKSGKPGPFLLSGSRDKTIKMWDISTGMCLMTLVGHDNWVRG 343
Query 221 VTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDA-SCTINSLCFSPCN-YWLCAATDKS 278
V P G S D +WD + + +L A + SL F + Y + + D++
Sbjct 344 VLFHPGGRFVVSCADDKTLRIWDYKNKRCMKTLSAHEHFVTSLDFHKASPYVVTGSVDQT 403
Query 279 VKIWD 283
VK+W+
Sbjct 404 VKVWE 408
> hsa:54554 WDR5B, FLJ11287, MGC49879; WD repeat domain 5B; K14963
COMPASS component SWD3
Length=330
Score = 109 bits (273), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 90/294 (30%), Positives = 144/294 (48%), Gaps = 21/294 (7%)
Query 10 FALSASAKMSVSV-DSP-LVFKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLN 67
ALS+SA S V ++P K L GHT+ V+++ + + SSS D+ II+W
Sbjct 13 LALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKF-SPNGEWLASSSADRLIIIWGAY 71
Query 68 DSPNAETVGFARRALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKH 127
D G + L GH+ + DV SSDS+ +S S DKTL+LWD+ G+ ++T + H
Sbjct 72 D-------GKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGH 124
Query 128 TSDVNSVAFSADNRQIVSGSRDRTVRLWNT-LADCKYTIEEGQHTDWVSCVRFSPSPKEP 186
++ V F+ + I+SGS D TV++W C T+ H+D VS V F+ S
Sbjct 125 SNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLS--AHSDPVSAVHFNCSGS-- 180
Query 187 LIVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYT-VTVSPDGSLCASGGKDGVAMLWDVS 245
LIVS +D L ++W + + LV + + V SP+G + D LWD S
Sbjct 181 LIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYS 240
Query 246 EGKHLYSL-----DASCTINSLCFSPCNYWLCAATDKSVKIWDLENKNVLDDIH 294
G+ L + + C + + + + + D V IW+L+ K ++ +
Sbjct 241 RGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ 294
Score = 79.0 bits (193), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 68/261 (26%), Positives = 115/261 (44%), Gaps = 55/261 (21%)
Query 28 FKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQ 87
++ L GH ++ ++ + S+ ++S+S DK + +W++ G + L GHS
Sbjct 75 YEKTLYGHNLEISDVAWSS-DSSRLVSASDDKTLKLWDVRS-------GKCLKTLKGHSN 126
Query 88 CVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGS 147
V + SN +SGS+D+T+++W++ G+ ++T H+ V++V F+ IVSGS
Sbjct 127 YVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGS 186
Query 148 RDRTVRLWNTLA-DCKYTIEEGQHTDWVSCVRFSPSPKEPL------------------- 187
D R+W+ + C T+ + + VS V+FSP+ K L
Sbjct 187 YDGLCRIWDAASGQCLKTLVDDDNPP-VSFVKFSPNGKYILTATLDNTLKLWDYSRGRCL 245
Query 188 ------------------------IVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTV 223
IVS D LV +W+L T ++ L GHT V+ +
Sbjct 246 KTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAAC 305
Query 224 SPDGSLCASGG--KDGVAMLW 242
P +L AS D LW
Sbjct 306 HPTENLIASAALENDKTIKLW 326
> sce:YBR198C TAF5, TAF90; Taf5p; K03130 transcription initiation
factor TFIID subunit 5
Length=798
Score = 109 bits (273), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 68/222 (30%), Positives = 109/222 (49%), Gaps = 6/222 (2%)
Query 80 RALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSAD 139
+ L GHS V S D+ + LSGS DKT+RLW ++ + +++ H V V+FS
Sbjct 519 KTLVGHSGTVYSTSFSPDNKYLLSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSFSPL 578
Query 140 NRQIVSGSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKV 199
+ S D+T RLW+ I G H + V CV F P+ + + DK ++
Sbjct 579 GHYFATASHDQTARLWSCDHIYPLRIFAG-HLNDVDCVSFHPN--GCYVFTGSSDKTCRM 635
Query 200 WSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSL--DASC 257
W ++T +GHT+ + ++ V PDG ++G +DG+ +WD+ GK L +
Sbjct 636 WDVSTGDSVRLFLGHTAPVISIAVCPDGRWLSTGSEDGIINVWDIGTGKRLKQMRGHGKN 695
Query 258 TINSLCFS-PCNYWLCAATDKSVKIWDLENKNVLDDIHPDQP 298
I SL +S N + D +V++WDL+ PD+P
Sbjct 696 AIYSLSYSKEGNVLISGGADHTVRVWDLKKATTEPSAEPDEP 737
Score = 57.0 bits (136), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 64/242 (26%), Positives = 100/242 (41%), Gaps = 48/242 (19%)
Query 123 TFQKHTSDVNSVAFSADNRQIVSGSRDRTVRLW-------------------NTLADCKY 163
TFQ D++ + FS D R +G +D +++W + CK
Sbjct 461 TFQNTNKDMSCLDFSDDCRIAAAGFQDSYIKIWSLDGSSLNNPNIALNNNDKDEDPTCKT 520
Query 164 TIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTV 223
+ H+ V FSP K ++S DK V++WS+ T + GH ++ V+
Sbjct 521 LV---GHSGTVYSTSFSPDNK--YLLSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSF 575
Query 224 SPDGSLCASGGKDGVAMLWDVSEGKHLYSL--------DASCTINSLCFSPCN-YWLCAA 274
SP G A+ D A LW H+Y L D C + F P Y +
Sbjct 576 SPLGHYFATASHDQTARLWSCD---HIYPLRIFAGHLNDVDC----VSFHPNGCYVFTGS 628
Query 275 TDKSVKIWDLENKN-VLDDIHPDQPVKSGIPWCTSLNWSYDGRTLFIGTTSGNIHVYEVA 333
+DK+ ++WD+ + V + PV S I C DGR L G+ G I+V+++
Sbjct 629 SDKTCRMWDVSTGDSVRLFLGHTAPVIS-IAVCP------DGRWLSTGSEDGIINVWDIG 681
Query 334 EG 335
G
Sbjct 682 TG 683
> mmu:140858 Wdr5, 2410008O07Rik, AA408785, AA960360, Big, Big-3;
WD repeat domain 5; K14963 COMPASS component SWD3
Length=334
Score = 109 bits (272), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 84/289 (29%), Positives = 137/289 (47%), Gaps = 19/289 (6%)
Query 13 SASAKMSVSVDSPLVFKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNA 72
SA+ V K L GHT V+++ + + SSS DK I +W D
Sbjct 22 SATQSKPTPVKPNYALKFTLAGHTKAVSSVKF-SPNGEWLASSSADKLIKIWGAYD---- 76
Query 73 ETVGFARRALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVN 132
G + ++GH + DV SSDSN +S S DKTL++WD++ G+ ++T + H++ V
Sbjct 77 ---GKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVF 133
Query 133 SVAFSADNRQIVSGSRDRTVRLWNT-LADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSC 191
F+ + IVSGS D +VR+W+ C T+ H+D VS V F+ LIVS
Sbjct 134 CCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLP--AHSDPVSAVHFNRDGS--LIVSS 189
Query 192 GWDKLVKVWSLTTCKLTTNLVGHTSVLYT-VTVSPDGSLCASGGKDGVAMLWDVSEGKHL 250
+D L ++W + + L+ + + V SP+G + D LWD S+GK L
Sbjct 190 SYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCL 249
Query 251 YSL-----DASCTINSLCFSPCNYWLCAATDKSVKIWDLENKNVLDDIH 294
+ + C + + + + + D V IW+L+ K ++ +
Sbjct 250 KTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ 298
Score = 84.0 bits (206), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 70/261 (26%), Positives = 117/261 (44%), Gaps = 55/261 (21%)
Query 28 FKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQ 87
F+ + GH ++ ++ + SN ++S+S DK + +W+++ G + L GHS
Sbjct 79 FEKTISGHKLGISDVAWSS-DSNLLVSASDDKTLKIWDVSS-------GKCLKTLKGHSN 130
Query 88 CVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGS 147
V + SN +SGS+D+++R+WD+ G+ ++T H+ V++V F+ D IVS S
Sbjct 131 YVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSS 190
Query 148 RDRTVRLWNTLA-DCKYTIEEGQHTDWVSCVRFSPSPKEPL------------------- 187
D R+W+T + C T+ + + VS V+FSP+ K L
Sbjct 191 YDGLCRIWDTASGQCLKTLIDDDNPP-VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCL 249
Query 188 ------------------------IVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTV 223
IVS D LV +W+L T ++ L GHT V+ +
Sbjct 250 KTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTAC 309
Query 224 SPDGSLCASGG--KDGVAMLW 242
P ++ AS D LW
Sbjct 310 HPTENIIASAALENDKTIKLW 330
Score = 38.9 bits (89), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 30/115 (26%), Positives = 52/115 (45%), Gaps = 14/115 (12%)
Query 52 IISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQ---CVQDVVISSDSNFALSGSWDK 108
I++++ D + +W+ + G + TGH C+ + + +SGS D
Sbjct 229 ILAATLDNTLKLWDYSK-------GKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDN 281
Query 109 TLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGS--RDRTVRLWNTLADC 161
+ +W+L E V+ Q HT V S A I S + D+T++LW + DC
Sbjct 282 LVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKS--DC 334
> hsa:11091 WDR5, BIG-3, SWD3; WD repeat domain 5; K14963 COMPASS
component SWD3
Length=334
Score = 109 bits (272), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 84/289 (29%), Positives = 137/289 (47%), Gaps = 19/289 (6%)
Query 13 SASAKMSVSVDSPLVFKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNA 72
SA+ V K L GHT V+++ + + SSS DK I +W D
Sbjct 22 SATQSKPTPVKPNYALKFTLAGHTKAVSSVKF-SPNGEWLASSSADKLIKIWGAYD---- 76
Query 73 ETVGFARRALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVN 132
G + ++GH + DV SSDSN +S S DKTL++WD++ G+ ++T + H++ V
Sbjct 77 ---GKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVF 133
Query 133 SVAFSADNRQIVSGSRDRTVRLWNT-LADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSC 191
F+ + IVSGS D +VR+W+ C T+ H+D VS V F+ LIVS
Sbjct 134 CCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLP--AHSDPVSAVHFNRDGS--LIVSS 189
Query 192 GWDKLVKVWSLTTCKLTTNLVGHTSVLYT-VTVSPDGSLCASGGKDGVAMLWDVSEGKHL 250
+D L ++W + + L+ + + V SP+G + D LWD S+GK L
Sbjct 190 SYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCL 249
Query 251 YSL-----DASCTINSLCFSPCNYWLCAATDKSVKIWDLENKNVLDDIH 294
+ + C + + + + + D V IW+L+ K ++ +
Sbjct 250 KTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ 298
Score = 84.0 bits (206), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 70/261 (26%), Positives = 117/261 (44%), Gaps = 55/261 (21%)
Query 28 FKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQ 87
F+ + GH ++ ++ + SN ++S+S DK + +W+++ G + L GHS
Sbjct 79 FEKTISGHKLGISDVAWSS-DSNLLVSASDDKTLKIWDVSS-------GKCLKTLKGHSN 130
Query 88 CVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGS 147
V + SN +SGS+D+++R+WD+ G+ ++T H+ V++V F+ D IVS S
Sbjct 131 YVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSS 190
Query 148 RDRTVRLWNTLA-DCKYTIEEGQHTDWVSCVRFSPSPKEPL------------------- 187
D R+W+T + C T+ + + VS V+FSP+ K L
Sbjct 191 YDGLCRIWDTASGQCLKTLIDDDNPP-VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCL 249
Query 188 ------------------------IVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTV 223
IVS D LV +W+L T ++ L GHT V+ +
Sbjct 250 KTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTAC 309
Query 224 SPDGSLCASGG--KDGVAMLW 242
P ++ AS D LW
Sbjct 310 HPTENIIASAALENDKTIKLW 330
Score = 38.9 bits (89), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 30/115 (26%), Positives = 52/115 (45%), Gaps = 14/115 (12%)
Query 52 IISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQ---CVQDVVISSDSNFALSGSWDK 108
I++++ D + +W+ + G + TGH C+ + + +SGS D
Sbjct 229 ILAATLDNTLKLWDYSK-------GKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDN 281
Query 109 TLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGS--RDRTVRLWNTLADC 161
+ +W+L E V+ Q HT V S A I S + D+T++LW + DC
Sbjct 282 LVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKS--DC 334
> dre:394246 pafah1b1a; platelet-activating factor acetylhydrolase,
isoform Ib, alpha subunit a; K01062 1-alkyl-2-acetylglycerophosphocholine
esterase [EC:3.1.1.47]
Length=410
Score = 109 bits (272), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 95/326 (29%), Positives = 141/326 (43%), Gaps = 41/326 (12%)
Query 29 KGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQC 88
K L GH VT + V S I+S+S D I VW+ ET F R L GH+
Sbjct 101 KYALSGHRSPVTRVIFHPVFS-VIVSASEDATIKVWD------HETGDF-ERTLKGHTDS 152
Query 89 VQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSR 148
VQD+ S S D T++LWD E +RT H +V+SVA + IVS SR
Sbjct 153 VQDISFDHTGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASR 212
Query 149 DRTVRLWNTLAD-CKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKL 207
D+T+++W C T H +WV VR P+ LI S D+ V+VW + T +
Sbjct 213 DKTIKMWEVATGYCVKTF--TGHREWVRMVR--PNQDGTLIASSSNDQTVRVWVVATKEC 268
Query 208 TTNLVGHTSVLYTVTVSPD--------------------GSLCASGGKDGVAMLWDVSEG 247
L H V+ ++ +P+ G SG +D +WDVS G
Sbjct 269 KAELREHEHVVECISWAPESAHPTILEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSIG 328
Query 248 KHLYSLDASCT-INSLCFSP-CNYWLCAATDKSVKIWDLENKNVLDDIHPDQPVKSGIPW 305
L +L + + P Y + A DK+++IWD +NK + + +
Sbjct 329 MCLMTLVGHDNWVRGVLVHPGGKYIVSCADDKTLRIWDYKNKRCTKTLSAHE------HF 382
Query 306 CTSLNWSYDGRTLFIGTTSGNIHVYE 331
TSL++ + G+ + V+E
Sbjct 383 VTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 98.6 bits (244), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 80/278 (28%), Positives = 121/278 (43%), Gaps = 33/278 (11%)
Query 28 FKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFA-RRALTGHS 86
F+ L+GHTD V IS + S S D I +W+ GF R + GH
Sbjct 142 FERTLKGHTDSVQDISFDHT-GKLLASCSADMTIKLWDFQ--------GFECIRTMHGHD 192
Query 87 QCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSG 146
V V I + + +S S DKT+++W++ G V+TF H V V + D I S
Sbjct 193 HNVSSVAIMPNGDHIVSASRDKTIKMWEVATGYCVKTFTGHREWVRMVRPNQDGTLIASS 252
Query 147 SRDRTVRLW-NTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLI----------------- 188
S D+TVR+W +CK + E +H V C+ ++P P I
Sbjct 253 SNDQTVRVWVVATKECKAELREHEHV--VECISWAPESAHPTILEATGSETKKSGKPGPF 310
Query 189 -VSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEG 247
+S DK +K+W ++ LVGH + + V V P G S D +WD
Sbjct 311 LLSGSRDKTIKMWDVSIGMCLMTLVGHDNWVRGVLVHPGGKYIVSCADDKTLRIWDYKNK 370
Query 248 KHLYSLDA-SCTINSLCFSP-CNYWLCAATDKSVKIWD 283
+ +L A + SL F Y + + D++VK+W+
Sbjct 371 RCTKTLSAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
> ath:AT3G49660 transducin family protein / WD-40 repeat family
protein; K14963 COMPASS component SWD3
Length=317
Score = 108 bits (271), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 88/281 (31%), Positives = 134/281 (47%), Gaps = 20/281 (7%)
Query 24 SPLVFKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLN--DSPNAETVGFARRA 81
+P V L H V+++ + + S+S DK I + +N + P AE V +
Sbjct 12 TPYVHSQTLTSHNRAVSSVKFSS-DGRLLASASADKTIRTYTINTINDPIAEPV----QE 66
Query 82 LTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNR 141
TGH + DV SSD+ F +S S DKTL+LWD+ G ++T HT+ V F+ +
Sbjct 67 FTGHENGISDVAFSSDARFIVSASDDKTLKLWDVETGSLIKTLIGHTNYAFCVNFNPQSN 126
Query 142 QIVSGSRDRTVRLWN-TLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVW 200
IVSGS D TVR+W+ T C + H+D V+ V F+ LIVS +D L ++W
Sbjct 127 MIVSGSFDETVRIWDVTTGKCLKVLP--AHSDPVTAVDFNRDGS--LIVSSSYDGLCRIW 182
Query 201 SLTTCKLTTNLV-GHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYS----LDA 255
T L+ + V SP+G G D LW++S K L + ++A
Sbjct 183 DSGTGHCVKTLIDDENPPVSFVRFSPNGKFILVGTLDNTLRLWNISSAKFLKTYTGHVNA 242
Query 256 SCTINSLCFSPCN--YWLCAATDKSVKIWDLENKNVLDDIH 294
I+S FS N + + D V +W+L +K +L +
Sbjct 243 QYCISS-AFSVTNGKRIVSGSEDNCVHMWELNSKKLLQKLE 282
Score = 88.2 bits (217), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 65/213 (30%), Positives = 100/213 (46%), Gaps = 11/213 (5%)
Query 32 LEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQD 91
L GHT++ ++ +SN I+S S D+ + +W++ T G + L HS V
Sbjct 109 LIGHTNYAFCVNF-NPQSNMIVSGSFDETVRIWDV-------TTGKCLKVLPAHSDPVTA 160
Query 92 VVISSDSNFALSGSWDKTLRLWDLNVGETVRTF-QKHTSDVNSVAFSADNRQIVSGSRDR 150
V + D + +S S+D R+WD G V+T V+ V FS + + I+ G+ D
Sbjct 161 VDFNRDGSLIVSSSYDGLCRIWDSGTGHCVKTLIDDENPPVSFVRFSPNGKFILVGTLDN 220
Query 151 TVRLWNTLADCKYTIEEGQHTDWVSCVRFSPS-PKEPLIVSCGWDKLVKVWSLTTCKLTT 209
T+RLWN ++ K+ H + C+ + S IVS D V +W L + KL
Sbjct 221 TLRLWN-ISSAKFLKTYTGHVNAQYCISSAFSVTNGKRIVSGSEDNCVHMWELNSKKLLQ 279
Query 210 NLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLW 242
L GHT + V P +L ASG D +W
Sbjct 280 KLEGHTETVMNVACHPTENLIASGSLDKTVRIW 312
Score = 62.8 bits (151), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 58/174 (33%), Positives = 85/174 (48%), Gaps = 13/174 (7%)
Query 31 VLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQ 90
VL H+D VTA+ + I+SSS D +W DS V + + + V
Sbjct 150 VLPAHSDPVTAVDF-NRDGSLIVSSSYDGLCRIW---DSGTGHCV---KTLIDDENPPVS 202
Query 91 DVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVN--SVAFSADN-RQIVSGS 147
V S + F L G+ D TLRLW+++ + ++T+ H + S AFS N ++IVSGS
Sbjct 203 FVRFSPNGKFILVGTLDNTLRLWNISSAKFLKTYTGHVNAQYCISSAFSVTNGKRIVSGS 262
Query 148 RDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWS 201
D V +W + EG HT+ V V P+ E LI S DK V++W+
Sbjct 263 EDNCVHMWELNSKKLLQKLEG-HTETVMNVACHPT--ENLIASGSLDKTVRIWT 313
> xla:446809 wdr5-a, MGC80538, big-3, swd3, xwdr5; WD repeat domain
5; K14963 COMPASS component SWD3
Length=334
Score = 108 bits (269), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 82/274 (29%), Positives = 133/274 (48%), Gaps = 19/274 (6%)
Query 28 FKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQ 87
K L GHT V+++ + + SSS DK I +W D G + ++GH
Sbjct 37 LKFTLAGHTKAVSSVKF-SPNGEWLASSSADKLIKIWGAYD-------GKFEKTISGHKL 88
Query 88 CVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGS 147
+ DV SSDSN +S S DKTL++WD++ G+ ++T + H++ V F+ + IVSGS
Sbjct 89 GISDVAWSSDSNLLVSASDDKTLKIWDISSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGS 148
Query 148 RDRTVRLWNT-LADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCK 206
D +VR+W+ C T+ H+D VS V F+ LIVS +D L ++W + +
Sbjct 149 FDESVRIWDVKTGKCLKTLP--AHSDPVSAVHFNRDGS--LIVSSSYDGLCRIWDTASGQ 204
Query 207 LTTNLVGHTSVLYT-VTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSL-----DASCTIN 260
L+ + + V SP+G + D LWD S+GK L + + C
Sbjct 205 CLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTCHKNEKYCIFA 264
Query 261 SLCFSPCNYWLCAATDKSVKIWDLENKNVLDDIH 294
+ + + + + D V IW+L+ K V+ +
Sbjct 265 NFSVTGGKWIVSGSEDNLVYIWNLQTKEVVQKLQ 298
Score = 84.3 bits (207), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 70/261 (26%), Positives = 117/261 (44%), Gaps = 55/261 (21%)
Query 28 FKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQ 87
F+ + GH ++ ++ + SN ++S+S DK + +W+++ G + L GHS
Sbjct 79 FEKTISGHKLGISDVAWSS-DSNLLVSASDDKTLKIWDISS-------GKCLKTLKGHSN 130
Query 88 CVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGS 147
V + SN +SGS+D+++R+WD+ G+ ++T H+ V++V F+ D IVS S
Sbjct 131 YVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSS 190
Query 148 RDRTVRLWNTLA-DCKYTIEEGQHTDWVSCVRFSPSPKEPL------------------- 187
D R+W+T + C T+ + + VS V+FSP+ K L
Sbjct 191 YDGLCRIWDTASGQCLKTLIDDDNPP-VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCL 249
Query 188 ------------------------IVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTV 223
IVS D LV +W+L T ++ L GHT V+ +
Sbjct 250 KTYTCHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEVVQKLQGHTDVVISTAC 309
Query 224 SPDGSLCASGG--KDGVAMLW 242
P ++ AS D LW
Sbjct 310 HPTENIIASAALENDKTIKLW 330
Score = 36.6 bits (83), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 4/62 (6%)
Query 102 LSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGS--RDRTVRLWNTLA 159
+SGS D + +W+L E V+ Q HT V S A I S + D+T++LW +
Sbjct 275 VSGSEDNLVYIWNLQTKEVVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWK--S 332
Query 160 DC 161
DC
Sbjct 333 DC 334
> dre:406372 wdr5, wu:fk47f04, zgc:56591, zgc:76895; WD repeat
domain 5; K14963 COMPASS component SWD3
Length=334
Score = 108 bits (269), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 82/275 (29%), Positives = 135/275 (49%), Gaps = 21/275 (7%)
Query 28 FKGVLEGHTDWVTAIS-TPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHS 86
K L GHT V+++ +P+ + SSS DK I +W D G + ++GH
Sbjct 37 LKFTLAGHTKAVSSVKFSPS--GEWLASSSADKLIKIWGAYD-------GKFEKTISGHK 87
Query 87 QCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSG 146
+ DV SSDSN +S S DKTL++WD++ G+ ++T + H++ V F+ + IVSG
Sbjct 88 LGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSG 147
Query 147 SRDRTVRLWNT-LADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTC 205
S D +VR+W+ C T+ H+D VS V F+ LIVS +D L ++W +
Sbjct 148 SFDESVRIWDVKTGKCLKTLP--AHSDPVSAVHFNRDGS--LIVSSSYDGLCRIWDTASG 203
Query 206 KLTTNLVGHTSVLYT-VTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSL-----DASCTI 259
+ L+ + + V SP+G + D LWD S+GK L + + C
Sbjct 204 QCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIF 263
Query 260 NSLCFSPCNYWLCAATDKSVKIWDLENKNVLDDIH 294
+ + + + + D V IW+L+ K ++ +
Sbjct 264 ANFSVTGGKWIVSGSEDNMVYIWNLQTKEIVQKLQ 298
Score = 83.6 bits (205), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 69/261 (26%), Positives = 117/261 (44%), Gaps = 55/261 (21%)
Query 28 FKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQ 87
F+ + GH ++ ++ + SN ++S+S DK + +W+++ G + L GHS
Sbjct 79 FEKTISGHKLGISDVAWSS-DSNLLVSASDDKTLKIWDVSS-------GKCLKTLKGHSN 130
Query 88 CVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGS 147
V + SN +SGS+D+++R+WD+ G+ ++T H+ V++V F+ D IVS S
Sbjct 131 YVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSS 190
Query 148 RDRTVRLWNTLA-DCKYTIEEGQHTDWVSCVRFSPSPKEPL------------------- 187
D R+W+T + C T+ + + VS V+FSP+ K L
Sbjct 191 YDGLCRIWDTASGQCLKTLIDDDNPP-VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCL 249
Query 188 ------------------------IVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTV 223
IVS D +V +W+L T ++ L GHT V+ +
Sbjct 250 KTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQTKEIVQKLQGHTDVVISTAC 309
Query 224 SPDGSLCASGG--KDGVAMLW 242
P ++ AS D LW
Sbjct 310 HPTENIIASAALENDKTIKLW 330
Score = 39.3 bits (90), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 30/115 (26%), Positives = 52/115 (45%), Gaps = 14/115 (12%)
Query 52 IISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQ---CVQDVVISSDSNFALSGSWDK 108
I++++ D + +W+ + G + TGH C+ + + +SGS D
Sbjct 229 ILAATLDNTLKLWDYSK-------GKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDN 281
Query 109 TLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGS--RDRTVRLWNTLADC 161
+ +W+L E V+ Q HT V S A I S + D+T++LW +DC
Sbjct 282 MVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWK--SDC 334
> xla:447447 wdr5-b, MGC81485, big-3, swd3, wdr5, xwdr5; WD repeat
domain 5; K14963 COMPASS component SWD3
Length=334
Score = 107 bits (268), Expect = 5e-23, Method: Compositional matrix adjust.
Identities = 82/274 (29%), Positives = 133/274 (48%), Gaps = 19/274 (6%)
Query 28 FKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQ 87
K L GHT V+++ + + SSS DK I +W D G + ++GH
Sbjct 37 LKFTLAGHTKAVSSVKF-SPNGEWLASSSADKLIKIWGAYD-------GKFEKTISGHKL 88
Query 88 CVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGS 147
+ DV SSDSN +S S DKTL++WD++ G+ ++T + H++ V F+ + IVSGS
Sbjct 89 GISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGS 148
Query 148 RDRTVRLWNT-LADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCK 206
D +VR+W+ C T+ H+D VS V F+ LIVS +D L ++W + +
Sbjct 149 FDESVRIWDVKTGKCLKTLP--AHSDPVSAVHFNRDGS--LIVSSSYDGLCRIWDTASGQ 204
Query 207 LTTNLVGHTSVLYT-VTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSL-----DASCTIN 260
L+ + + V SP+G + D LWD S+GK L + + C
Sbjct 205 CLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTCHKNEKYCIFA 264
Query 261 SLCFSPCNYWLCAATDKSVKIWDLENKNVLDDIH 294
+ + + + + D V IW+L+ K V+ +
Sbjct 265 NFSVTGGKWIVSGSEDNLVYIWNLQTKEVVQKLQ 298
Score = 84.0 bits (206), Expect = 9e-16, Method: Compositional matrix adjust.
Identities = 70/261 (26%), Positives = 117/261 (44%), Gaps = 55/261 (21%)
Query 28 FKGVLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQ 87
F+ + GH ++ ++ + SN ++S+S DK + +W+++ G + L GHS
Sbjct 79 FEKTISGHKLGISDVAWSS-DSNLLVSASDDKTLKIWDVSS-------GKCLKTLKGHSN 130
Query 88 CVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGS 147
V + SN +SGS+D+++R+WD+ G+ ++T H+ V++V F+ D IVS S
Sbjct 131 YVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSS 190
Query 148 RDRTVRLWNTLA-DCKYTIEEGQHTDWVSCVRFSPSPKEPL------------------- 187
D R+W+T + C T+ + + VS V+FSP+ K L
Sbjct 191 YDGLCRIWDTASGQCLKTLIDDDNPP-VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCL 249
Query 188 ------------------------IVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTV 223
IVS D LV +W+L T ++ L GHT V+ +
Sbjct 250 KTYTCHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEVVQKLQGHTDVVISTAC 309
Query 224 SPDGSLCASGG--KDGVAMLW 242
P ++ AS D LW
Sbjct 310 HPTENIIASAALENDKTIKLW 330
Score = 36.6 bits (83), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 4/62 (6%)
Query 102 LSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGS--RDRTVRLWNTLA 159
+SGS D + +W+L E V+ Q HT V S A I S + D+T++LW +
Sbjct 275 VSGSEDNLVYIWNLQTKEVVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWK--S 332
Query 160 DC 161
DC
Sbjct 333 DC 334
> mmu:69544 Wdr5b, 2310009C03Rik, AI606931; WD repeat domain 5B;
K14963 COMPASS component SWD3
Length=328
Score = 106 bits (264), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 77/287 (26%), Positives = 140/287 (48%), Gaps = 21/287 (7%)
Query 45 PTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQDVVISSDSNFALSG 104
P ++ +++S+ R + + P R L GHS + V S + + S
Sbjct 7 PAERAQSLLSAPRRE--------EEPQKPNYAL-RLTLAGHSAAISSVKFSPNGEWLASS 57
Query 105 SWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRTVRLWNTLA-DCKY 163
+ D + +W G +T H+ +++ VA+S+D+ ++VS S D+T+++W+ + C
Sbjct 58 AADALIIIWGAYDGNCKKTLYGHSLEISDVAWSSDSSRLVSASDDKTLKVWDMRSGKCLK 117
Query 164 TIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTV 223
T++ H+D+V C F+P LIVS +D+ VK+W + T K L H+ + V
Sbjct 118 TLK--GHSDFVFCCDFNPPSN--LIVSGSFDESVKIWEVKTGKCLKTLSAHSDPISAVNF 173
Query 224 SPDGSLCASGGKDGVAMLWDVSEGKHLYSL--DASCTINSLCFSP-CNYWLCAATDKSVK 280
+ +GSL SG DG+ +WD + G+ L +L + + ++ + FSP Y L A D ++K
Sbjct 174 NCNGSLIVSGSYDGLCRIWDAASGQCLRTLADEGNPPVSFVKFSPNGKYILTATLDNTLK 233
Query 281 IWDLENKNVLDDIHPDQPVKSGIPWCTSLNWSYDGRTLFIGTTSGNI 327
+WD L + K +C ++S GR + + N+
Sbjct 234 LWDYSRGRCLKTYTGHKNEK----YCLFASFSVTGRKWVVSGSEDNM 276
Score = 101 bits (252), Expect = 4e-21, Method: Compositional matrix adjust.
Identities = 86/293 (29%), Positives = 136/293 (46%), Gaps = 25/293 (8%)
Query 12 LSASAKMSVSVDSPLVFKGVLEGHTDWVTAISTPTVKSNT--IISSSRDKKIIVWNLNDS 69
LSA + + L GH+ AIS+ N + SS+ D II+W D
Sbjct 15 LSAPRREEEPQKPNYALRLTLAGHS---AAISSVKFSPNGEWLASSAADALIIIWGAYD- 70
Query 70 PNAETVGFARRALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTS 129
G ++ L GHS + DV SSDS+ +S S DKTL++WD+ G+ ++T + H+
Sbjct 71 ------GNCKKTLYGHSLEISDVAWSSDSSRLVSASDDKTLKVWDMRSGKCLKTLKGHSD 124
Query 130 DVNSVAFSADNRQIVSGSRDRTVRLWNT-LADCKYTIEEGQHTDWVSCVRFSPSPKEPLI 188
V F+ + IVSGS D +V++W C T+ H+D +S V F+ + LI
Sbjct 125 FVFCCDFNPPSNLIVSGSFDESVKIWEVKTGKCLKTLS--AHSDPISAVNFNCNGS--LI 180
Query 189 VSCGWDKLVKVWSLTT--CKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSE 246
VS +D L ++W + C T G+ V + V SP+G + D LWD S
Sbjct 181 VSGSYDGLCRIWDAASGQCLRTLADEGNPPVSF-VKFSPNGKYILTATLDNTLKLWDYSR 239
Query 247 GKHLYSL-----DASCTINSLCFSPCNYWLCAATDKSVKIWDLENKNVLDDIH 294
G+ L + + C S + + + + D V IW+L+ K ++ +
Sbjct 240 GRCLKTYTGHKNEKYCLFASFSVTGRKWVVSGSEDNMVYIWNLQTKEIVQRLQ 292
Score = 78.2 bits (191), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 55/205 (26%), Positives = 101/205 (49%), Gaps = 11/205 (5%)
Query 32 LEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQD 91
L+GH+D+V SN I+S S D+ + +W + G + L+ HS +
Sbjct 119 LKGHSDFVFCCDF-NPPSNLIVSGSFDESVKIWEVK-------TGKCLKTLSAHSDPISA 170
Query 92 VVISSDSNFALSGSWDKTLRLWDLNVGETVRTF-QKHTSDVNSVAFSADNRQIVSGSRDR 150
V + + + +SGS+D R+WD G+ +RT + V+ V FS + + I++ + D
Sbjct 171 VNFNCNGSLIVSGSYDGLCRIWDAASGQCLRTLADEGNPPVSFVKFSPNGKYILTATLDN 230
Query 151 TVRLWN-TLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTT 209
T++LW+ + C T ++ + FS + ++ +VS D +V +W+L T ++
Sbjct 231 TLKLWDYSRGRCLKTYTGHKNEKYCLFASFSVTGRK-WVVSGSEDNMVYIWNLQTKEIVQ 289
Query 210 NLVGHTSVLYTVTVSPDGSLCASGG 234
L GHT V+ + P ++ AS
Sbjct 290 RLQGHTDVVISAACHPTKNIIASAA 314
Score = 37.4 bits (85), Expect = 0.078, Method: Compositional matrix adjust.
Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 14/115 (12%)
Query 52 IISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQ---CVQDVVISSDSNFALSGSWDK 108
I++++ D + +W+ + G + TGH C+ + + +SGS D
Sbjct 223 ILTATLDNTLKLWDY-------SRGRCLKTYTGHKNEKYCLFASFSVTGRKWVVSGSEDN 275
Query 109 TLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGS--RDRTVRLWNTLADC 161
+ +W+L E V+ Q HT V S A I S + D+T+++W++ DC
Sbjct 276 MVYIWNLQTKEIVQRLQGHTDVVISAACHPTKNIIASAALENDKTIKVWSS--DC 328
> cel:C14B1.4 tag-125; Temporarily Assigned Gene name family member
(tag-125); K14963 COMPASS component SWD3
Length=376
Score = 104 bits (259), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 71/255 (27%), Positives = 129/255 (50%), Gaps = 11/255 (4%)
Query 82 LTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNR 141
L GH++ + S + + S DKT+++W+++ RT H VN +A+S+D+R
Sbjct 83 LEGHTKSISSAKFSPCGKYLGTSSADKTVKIWNMDHMICERTLTGHKLGVNDIAWSSDSR 142
Query 142 QIVSGSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWS 201
+VS S D+T++++ + + T H ++V C F+P + L+VS +D+ V++W
Sbjct 143 CVVSASDDKTLKIFEIVTS-RMTKTLKGHNNYVFCCNFNP--QSSLVVSGSFDESVRIWD 199
Query 202 LTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSL--DASCTI 259
+ T L H+ + V+ + DGSL ASG DG+ +WD + G+ + +L D + +
Sbjct 200 VKTGMCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQCIKTLVDDENPPV 259
Query 260 NSLCFSP-CNYWLCAATDKSVKIWDLENKNVLDDIHPDQPVKSGIPWCTSLNWSYDGRTL 318
+ FSP Y L + D ++K+WD L + K +C N+S G
Sbjct 260 AFVKFSPNGKYILASNLDSTLKLWDFSKGKTLKQYTGHENSK----YCIFANFSVTGGKW 315
Query 319 FI-GTTSGNIHVYEV 332
I G+ I+++ +
Sbjct 316 IISGSEDCKIYIWNL 330
Score = 81.3 bits (199), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 70/260 (26%), Positives = 116/260 (44%), Gaps = 59/260 (22%)
Query 32 LEGHTDWVTAIS-TPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQ 90
LEGHT +++ +P K + +SS DK + +WN++ R LTGH V
Sbjct 83 LEGHTKSISSAKFSPCGK--YLGTSSADKTVKIWNMDHM-------ICERTLTGHKLGVN 133
Query 91 DVVISSDS------------------------------------NF------ALSGSWDK 108
D+ SSDS NF +SGS+D+
Sbjct 134 DIAWSSDSRCVVSASDDKTLKIFEIVTSRMTKTLKGHNNYVFCCNFNPQSSLVVSGSFDE 193
Query 109 TLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRTVRLWNTL-ADCKYTIEE 167
++R+WD+ G ++T H+ V++V+F+ D I SGS D VR+W+T C T+ +
Sbjct 194 SVRIWDVKTGMCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQCIKTLVD 253
Query 168 GQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTVS--- 224
++ V+ V+FSP+ K I++ D +K+W + K GH + Y + +
Sbjct 254 DENPP-VAFVKFSPNGK--YILASNLDSTLKLWDFSKGKTLKQYTGHENSKYCIFANFSV 310
Query 225 PDGSLCASGGKDGVAMLWDV 244
G SG +D +W++
Sbjct 311 TGGKWIISGSEDCKIYIWNL 330
> xla:734230 fbxw7; F-box and WD repeat domain containing 7; K10260
F-box and WD-40 domain protein 7
Length=706
Score = 103 bits (257), Expect = 8e-22, Method: Compositional matrix adjust.
Identities = 87/290 (30%), Positives = 131/290 (45%), Gaps = 35/290 (12%)
Query 31 VLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQ 90
VL+GH D V I+ N I+S S D + VW + G R L GH+ V
Sbjct 374 VLKGHDDHV--ITCLQFCGNRIVSGSDDNTLKVW-------SAVTGKCLRTLVGHTGGVW 424
Query 91 DVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDR 150
+ N +SGS D+TL++W+ GE + T HTS V + +++VSGSRD
Sbjct 425 SSQMRD--NIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH--EKRVVSGSRDA 480
Query 151 TVRLWNTLADCKYTIEEGQ-------HTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLT 203
T+R+W+ IE GQ H V CV++ +VS +D +VKVW
Sbjct 481 TLRVWD--------IETGQCLHVLMGHVAAVRCVQYDGR----RVVSGAYDFMVKVWDPE 528
Query 204 TCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASCTINSLC 263
T L GHT+ +Y++ DG SG D +WDV G +++L ++ S
Sbjct 529 TETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGM 586
Query 264 FSPCNYWLCAATDKSVKIWDLENKNVLDDIHPDQPVKSGIPWCTSLNWSY 313
N + D +VKIWD++ L + +S + C N ++
Sbjct 587 ELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT-CLQFNKNF 635
Score = 68.6 bits (166), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 60/214 (28%), Positives = 100/214 (46%), Gaps = 25/214 (11%)
Query 31 VLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQ 90
VL GH V A+ ++S + D + VW+ P ET L GH+ V
Sbjct 495 VLMGH---VAAVRCVQYDGRRVVSGAYDFMVKVWD----PETET---CLHTLQGHTNRVY 544
Query 91 DVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDR 150
+ D +SGS D ++R+WD+ G + T H S + + DN +VSG+ D
Sbjct 545 SLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELK-DN-ILVSGNADS 600
Query 151 TVRLWN-TLADCKYTIE-EGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLT 208
TV++W+ C T++ +H V+C++F+ + +++ D VK+W L T +
Sbjct 601 TVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN----FVITSSDDGTVKLWGLKTGEFI 656
Query 209 TNLV-----GHTSVLYTVTVSPDGSLCASGGKDG 237
NLV G V++ + S +CA G ++G
Sbjct 657 RNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNG 690
> hsa:55294 FBXW7, AGO, CDC4, DKFZp686F23254, FBW6, FBW7, FBX30,
FBXO30, FBXW6, FLJ16457, SEL-10, SEL10; F-box and WD repeat
domain containing 7; K10260 F-box and WD-40 domain protein
7
Length=589
Score = 103 bits (256), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 87/290 (30%), Positives = 131/290 (45%), Gaps = 35/290 (12%)
Query 31 VLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQ 90
VL+GH D V I+ N I+S S D + VW + G R L GH+ V
Sbjct 257 VLKGHDDHV--ITCLQFCGNRIVSGSDDNTLKVW-------SAVTGKCLRTLVGHTGGVW 307
Query 91 DVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDR 150
+ N +SGS D+TL++W+ GE + T HTS V + +++VSGSRD
Sbjct 308 SSQMRD--NIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH--EKRVVSGSRDA 363
Query 151 TVRLWNTLADCKYTIEEGQ-------HTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLT 203
T+R+W+ IE GQ H V CV++ +VS +D +VKVW
Sbjct 364 TLRVWD--------IETGQCLHVLMGHVAAVRCVQYDGR----RVVSGAYDFMVKVWDPE 411
Query 204 TCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASCTINSLC 263
T L GHT+ +Y++ DG SG D +WDV G +++L ++ S
Sbjct 412 TETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGM 469
Query 264 FSPCNYWLCAATDKSVKIWDLENKNVLDDIHPDQPVKSGIPWCTSLNWSY 313
N + D +VKIWD++ L + +S + C N ++
Sbjct 470 ELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT-CLQFNKNF 518
Score = 71.6 bits (174), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 60/224 (26%), Positives = 101/224 (45%), Gaps = 22/224 (9%)
Query 32 LEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQD 91
L GHT V + + ++S SRD + VW++ G L GH V+
Sbjct 339 LYGHTSTVRCMH---LHEKRVVSGSRDATLRVWDIE-------TGQCLHVLMGHVAAVR- 387
Query 92 VVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRT 151
+ D +SG++D +++WD + T Q HT+ V S+ F D +VSGS D +
Sbjct 388 -CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTS 444
Query 152 VRLWNT-LADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTN 210
+R+W+ +C +T+ H S + K+ ++VS D VK+W + T +
Sbjct 445 IRVWDVETGNCIHTLT--GHQSLTSGMEL----KDNILVSGNADSTVKIWDIKTGQCLQT 498
Query 211 LVGHTSVLYTVT-VSPDGSLCASGGKDGVAMLWDVSEGKHLYSL 253
L G VT + + + + DG LWD+ G+ + +L
Sbjct 499 LQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNL 542
Score = 68.9 bits (167), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 60/214 (28%), Positives = 100/214 (46%), Gaps = 25/214 (11%)
Query 31 VLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQ 90
VL GH V A+ ++S + D + VW+ P ET L GH+ V
Sbjct 378 VLMGH---VAAVRCVQYDGRRVVSGAYDFMVKVWD----PETET---CLHTLQGHTNRVY 427
Query 91 DVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDR 150
+ D +SGS D ++R+WD+ G + T H S + + DN +VSG+ D
Sbjct 428 S--LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELK-DN-ILVSGNADS 483
Query 151 TVRLWN-TLADCKYTIE-EGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLT 208
TV++W+ C T++ +H V+C++F+ + +++ D VK+W L T +
Sbjct 484 TVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN----FVITSSDDGTVKLWDLKTGEFI 539
Query 209 TNLV-----GHTSVLYTVTVSPDGSLCASGGKDG 237
NLV G V++ + S +CA G ++G
Sbjct 540 RNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNG 573
> dre:641491 taf5, MGC123129, wu:fc38g05, zgc:123129; TAF5 RNA
polymerase II, TATA box binding protein (TBP)-associated factor;
K03130 transcription initiation factor TFIID subunit 5
Length=743
Score = 103 bits (256), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 69/219 (31%), Positives = 102/219 (46%), Gaps = 7/219 (3%)
Query 80 RALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSAD 139
+ L GHS V V S D N+ LS S D T+RLW L + ++ H V FS
Sbjct 480 KILHGHSGPVYGVSFSPDRNYLLSSSEDGTIRLWSLQTFTCLVGYKGHNYPVWDTQFSPF 539
Query 140 NRQIVSGSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKV 199
VSG DR RLW T I G D V+C RF P+ + + D+ V++
Sbjct 540 GYYFVSGGHDRVARLWATDHYQPLRIFAGHLAD-VTCTRFHPNSN--YVATGSSDRTVRL 596
Query 200 WSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDA-SCT 258
W + GH ++++ SP+G ASG DG +LWD+ G + L + T
Sbjct 597 WDVLNGNCVRIFTGHKGPIHSLAFSPNGKFLASGSTDGRVLLWDIGHGLMIAELKGHTGT 656
Query 259 INSLCFSPCNYWLCAAT-DKSVKIWDLENKNVLDDIHPD 296
I +L FS + + + D +V++WD+ +DD+ D
Sbjct 657 IYALKFSRDGEIIASGSIDNTVRLWDV--MRAIDDVETD 693
Score = 97.1 bits (240), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 69/214 (32%), Positives = 101/214 (47%), Gaps = 11/214 (5%)
Query 31 VLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQ 90
+L GH+ V +S + N ++SSS D I +W+L VG+ GH+ V
Sbjct 481 ILHGHSGPVYGVSF-SPDRNYLLSSSEDGTIRLWSLQTF--TCLVGYK-----GHNYPVW 532
Query 91 DVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDR 150
D S + +SG D+ RLW + + +R F H +DV F ++ + +GS DR
Sbjct 533 DTQFSPFGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVTCTRFHPNSNYVATGSSDR 592
Query 151 TVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTN 210
TVRLW+ L I G H + + FSP+ K + S D V +W + +
Sbjct 593 TVRLWDVLNGNCVRIFTG-HKGPIHSLAFSPNGK--FLASGSTDGRVLLWDIGHGLMIAE 649
Query 211 LVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDV 244
L GHT +Y + S DG + ASG D LWDV
Sbjct 650 LKGHTGTIYALKFSRDGEIIASGSIDNTVRLWDV 683
Score = 63.2 bits (152), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 35/110 (31%), Positives = 55/110 (50%), Gaps = 7/110 (6%)
Query 49 SNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQDVVISSDSNFALSGSWDK 108
SN + + S D+ + +W++ + G R TGH + + S + F SGS D
Sbjct 582 SNYVATGSSDRTVRLWDVLN-------GNCVRIFTGHKGPIHSLAFSPNGKFLASGSTDG 634
Query 109 TLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRTVRLWNTL 158
+ LWD+ G + + HT + ++ FS D I SGS D TVRLW+ +
Sbjct 635 RVLLWDIGHGLMIAELKGHTGTIYALKFSRDGEIIASGSIDNTVRLWDVM 684
Score = 62.0 bits (149), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 64/250 (25%), Positives = 102/250 (40%), Gaps = 50/250 (20%)
Query 123 TFQKHTSDVNSVAFSADNRQIVSGSRDRTVRLWN----------TLADCKYTIEEGQ--- 169
TF + +V F+ D+ I G D TVR+W+ + AD +E
Sbjct 408 TFLNAYQGLTAVDFTDDSSLIAGGFADSTVRVWSVTPKKLRKVKSAADLNLIDKESDDVL 467
Query 170 -----------------HTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTNLV 212
H+ V V FSP ++S D +++WSL T
Sbjct 468 ERIMDEKTSSESKILHGHSGPVYGVSFSPD--RNYLLSSSEDGTIRLWSLQTFTCLVGYK 525
Query 213 GHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHL-----YSLDASCTINSLCFSP- 266
GH ++ SP G SGG D VA LW + L + D +CT F P
Sbjct 526 GHNYPVWDTQFSPFGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVTCT----RFHPN 581
Query 267 CNYWLCAATDKSVKIWDLENKNVLDDIHPDQ-PVKSGIPWCTSLNWSYDGRTLFIGTTSG 325
NY ++D++V++WD+ N N + + P+ SL +S +G+ L G+T G
Sbjct 582 SNYVATGSSDRTVRLWDVLNGNCVRIFTGHKGPIH-------SLAFSPNGKFLASGSTDG 634
Query 326 NIHVYEVAEG 335
+ ++++ G
Sbjct 635 RVLLWDIGHG 644
> dre:564991 fbxw7, si:ch211-208n2.1; F-box and WD repeat domain
containing 7; K10260 F-box and WD-40 domain protein 7
Length=605
Score = 103 bits (256), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 87/290 (30%), Positives = 131/290 (45%), Gaps = 35/290 (12%)
Query 31 VLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQ 90
VL+GH D V I+ N I+S S D + VW + G R L GH+ V
Sbjct 273 VLKGHDDHV--ITCLQFCGNRIVSGSDDNTLKVW-------SAVTGKCLRTLVGHTGGVW 323
Query 91 DVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDR 150
+ N +SGS D+TL++W+ GE + T HTS V + +++VSGSRD
Sbjct 324 SSQMRD--NIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH--EKRVVSGSRDA 379
Query 151 TVRLWNTLADCKYTIEEGQ-------HTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLT 203
T+R+W+ IE GQ H V CV++ +VS +D +VKVW
Sbjct 380 TLRVWD--------IETGQCLHVLMGHVAAVRCVQYDGR----RVVSGAYDFMVKVWDPE 427
Query 204 TCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASCTINSLC 263
T L GHT+ +Y++ DG SG D +WDV G +++L ++ S
Sbjct 428 TETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGM 485
Query 264 FSPCNYWLCAATDKSVKIWDLENKNVLDDIHPDQPVKSGIPWCTSLNWSY 313
N + D +VKIWD++ L + +S + C N ++
Sbjct 486 ELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSAVT-CLQFNKNF 534
Score = 71.2 bits (173), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 59/224 (26%), Positives = 100/224 (44%), Gaps = 22/224 (9%)
Query 32 LEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQD 91
L GHT V + + ++S SRD + VW++ G L GH V+
Sbjct 355 LYGHTSTVRCMH---LHEKRVVSGSRDATLRVWDIE-------TGQCLHVLMGHVAAVR- 403
Query 92 VVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRT 151
+ D +SG++D +++WD + T Q HT+ V S+ F D +VSGS D +
Sbjct 404 -CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTS 460
Query 152 VRLWNT-LADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTN 210
+R+W+ +C +T+ H S + K+ ++VS D VK+W + T +
Sbjct 461 IRVWDVETGNCIHTLT--GHQSLTSGMEL----KDNILVSGNADSTVKIWDIKTGQCLQT 514
Query 211 LVG-HTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSL 253
L G H + + + + DG LWD+ G+ + +L
Sbjct 515 LQGPHKHQSAVTCLQFNKNFVITSSDDGTVKLWDLRTGEFIRNL 558
Score = 67.8 bits (164), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 60/214 (28%), Positives = 100/214 (46%), Gaps = 25/214 (11%)
Query 31 VLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQ 90
VL GH V A+ ++S + D + VW+ P ET L GH+ V
Sbjct 394 VLMGH---VAAVRCVQYDGRRVVSGAYDFMVKVWD----PETET---CLHTLQGHTNRVY 443
Query 91 DVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDR 150
+ D +SGS D ++R+WD+ G + T H S + + DN +VSG+ D
Sbjct 444 S--LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELK-DN-ILVSGNADS 499
Query 151 TVRLWN-TLADCKYTIE-EGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLT 208
TV++W+ C T++ +H V+C++F+ + +++ D VK+W L T +
Sbjct 500 TVKIWDIKTGQCLQTLQGPHKHQSAVTCLQFNKN----FVITSSDDGTVKLWDLRTGEFI 555
Query 209 TNLV-----GHTSVLYTVTVSPDGSLCASGGKDG 237
NLV G V++ + S +CA G ++G
Sbjct 556 RNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNG 589
> mmu:50754 Fbxw7, 1110001A17Rik, AGO, Cdc4, Fbw7, Fbwd6, Fbx30,
Fbxo30, Fbxw6, SEL-10; F-box and WD-40 domain protein 7;
K10260 F-box and WD-40 domain protein 7
Length=710
Score = 103 bits (256), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 87/290 (30%), Positives = 131/290 (45%), Gaps = 35/290 (12%)
Query 31 VLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQ 90
VL+GH D V I+ N I+S S D + VW + G R L GH+ V
Sbjct 378 VLKGHDDHV--ITCLQFCGNRIVSGSDDNTLKVW-------SAVTGKCLRTLVGHTGGVW 428
Query 91 DVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDR 150
+ N +SGS D+TL++W+ GE + T HTS V + +++VSGSRD
Sbjct 429 SSQMRD--NIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH--EKRVVSGSRDA 484
Query 151 TVRLWNTLADCKYTIEEGQ-------HTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLT 203
T+R+W+ IE GQ H V CV++ +VS +D +VKVW
Sbjct 485 TLRVWD--------IETGQCLHVLMGHVAAVRCVQYDGR----RVVSGAYDFMVKVWDPE 532
Query 204 TCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASCTINSLC 263
T L GHT+ +Y++ DG SG D +WDV G +++L ++ S
Sbjct 533 TETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGM 590
Query 264 FSPCNYWLCAATDKSVKIWDLENKNVLDDIHPDQPVKSGIPWCTSLNWSY 313
N + D +VKIWD++ L + +S + C N ++
Sbjct 591 ELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVT-CLQFNKNF 639
Score = 71.6 bits (174), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 60/224 (26%), Positives = 102/224 (45%), Gaps = 22/224 (9%)
Query 32 LEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQD 91
L GHT V + + ++S SRD + VW++ G L GH V+
Sbjct 460 LYGHTSTVRCMH---LHEKRVVSGSRDATLRVWDIE-------TGQCLHVLMGHVAAVR- 508
Query 92 VVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRT 151
+ D +SG++D +++WD + T Q HT+ V S+ F D +VSGS D +
Sbjct 509 -CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTS 565
Query 152 VRLWNT-LADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTN 210
+R+W+ +C +T+ H S + K+ ++VS D VK+W + T +
Sbjct 566 IRVWDVETGNCIHTLT--GHQSLTSGMEL----KDNILVSGNADSTVKIWDIKTGQCLQT 619
Query 211 LVGHTSVLYTVT-VSPDGSLCASGGKDGVAMLWDVSEGKHLYSL 253
L G + VT + + + + DG LWD+ G+ + +L
Sbjct 620 LQGPSKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNL 663
Score = 67.8 bits (164), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 60/214 (28%), Positives = 100/214 (46%), Gaps = 25/214 (11%)
Query 31 VLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQ 90
VL GH V A+ ++S + D + VW+ P ET L GH+ V
Sbjct 499 VLMGH---VAAVRCVQYDGRRVVSGAYDFMVKVWD----PETET---CLHTLQGHTNRVY 548
Query 91 DVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDR 150
+ D +SGS D ++R+WD+ G + T H S + + DN +VSG+ D
Sbjct 549 SLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELK-DN-ILVSGNADS 604
Query 151 TVRLWN-TLADCKYTIE-EGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLT 208
TV++W+ C T++ +H V+C++F+ + +++ D VK+W L T +
Sbjct 605 TVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKN----FVITSSDDGTVKLWDLKTGEFI 660
Query 209 TNLV-----GHTSVLYTVTVSPDGSLCASGGKDG 237
NLV G V++ + S +CA G ++G
Sbjct 661 RNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNG 694
> dre:406291 katnb1, wu:fj32f02, wu:fj65h01, zgc:56071; katanin
p80 (WD repeat containing) subunit B 1
Length=694
Score = 102 bits (253), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 63/216 (29%), Positives = 104/216 (48%), Gaps = 6/216 (2%)
Query 81 ALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADN 140
+LTGH+ V + +S ++GS +LRLWDL + +RT H + ++S+ F
Sbjct 58 SLTGHTSAVGCIQFNSSEERVVAGSLSGSLRLWDLEAAKILRTLMGHKASISSLDFHPMG 117
Query 141 RQIVSGSRDRTVRLWNTLAD-CKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKV 199
+ SGS D ++LW+ C + + HT V C+ FSP K + S D VK+
Sbjct 118 EYLASGSVDSNIKLWDVRRKGCVFRYK--GHTQAVRCLAFSPDGK--WLASASDDSTVKL 173
Query 200 WSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASC-T 258
W L K+ T HTS + V P+ L ASG D LWD+ + + S +
Sbjct 174 WDLIAGKMITEFTSHTSAVNVVQFHPNEYLLASGSADRTVKLWDLEKFNMIGSSEGETGV 233
Query 259 INSLCFSPCNYWLCAATDKSVKIWDLENKNVLDDIH 294
+ S+ F+P L + ++ +++++ E D +H
Sbjct 234 VRSVLFNPDGSCLYSGSENTLRVYGWEPDRCFDVVH 269
Score = 34.7 bits (78), Expect = 0.49, Method: Compositional matrix adjust.
Identities = 35/135 (25%), Positives = 68/135 (50%), Gaps = 10/135 (7%)
Query 201 SLTTCKLTTNLVGHTSVLYTVTVSPD-GSLCASGGKDGVAMLWDVSEGKHLYSLDA-SCT 258
++T+ KL +V H+S + ++ + G L A+GG+D +W VS+ + SL +
Sbjct 7 TITSWKLQ-EIVAHSSNVSSLVLGKSSGRLLATGGEDCRVNIWAVSKPNCIMSLTGHTSA 65
Query 259 INSLCFSPCNYWLCAAT-DKSVKIWDLENKNVLDDIHPDQPVKSGIPWCTSLNWSYDGRT 317
+ + F+ + A + S+++WDLE +L + K+ I +SL++ G
Sbjct 66 VGCIQFNSSEERVVAGSLSGSLRLWDLEAAKILRTLMGH---KASI---SSLDFHPMGEY 119
Query 318 LFIGTTSGNIHVYEV 332
L G+ NI +++V
Sbjct 120 LASGSVDSNIKLWDV 134
> ath:AT4G02730 transducin family protein / WD-40 repeat family
protein
Length=333
Score = 101 bits (252), Expect = 4e-21, Method: Compositional matrix adjust.
Identities = 71/230 (30%), Positives = 115/230 (50%), Gaps = 13/230 (5%)
Query 63 VWNLNDSPNAETVGFAR--------RALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWD 114
V N N + NA T G + L GH+ + V S+D N S S DKT+ LW
Sbjct 12 VANANSTGNAGTSGNVPIYKPYRHLKTLEGHTAAISCVKFSNDGNLLASASVDKTMILWS 71
Query 115 LNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRTVRLWNTLADCKYTIEEGQHTDWV 174
+ ++ H+S ++ +A+S+D+ S S D T+R+W+ + + HT++V
Sbjct 72 ATNYSLIHRYEGHSSGISDLAWSSDSHYTCSASDDCTLRIWDARSPYECLKVLRGHTNFV 131
Query 175 SCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGG 234
CV F+P LIVS +D+ +++W + T K + H+ + +V + DGSL S
Sbjct 132 FCVNFNPPSN--LIVSGSFDETIRIWEVKTGKCVRMIKAHSMPISSVHFNRDGSLIVSAS 189
Query 235 KDGVAMLWDVSEGKHLYSL--DASCTINSLCFSPCNYWLCAAT-DKSVKI 281
DG +WD EG L +L D S ++ FSP ++ AT D ++K+
Sbjct 190 HDGSCKIWDAKEGTCLKTLIDDKSPAVSFAKFSPNGKFILVATLDSTLKL 239
Score = 85.1 bits (209), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 69/258 (26%), Positives = 129/258 (50%), Gaps = 18/258 (6%)
Query 33 EGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQDV 92
EGH+ ++ ++ + S+ S+S D + +W+ A + + L GH+ V V
Sbjct 82 EGHSSGISDLAWSS-DSHYTCSASDDCTLRIWD------ARSPYECLKVLRGHTNFVFCV 134
Query 93 VISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRTV 152
+ SN +SGS+D+T+R+W++ G+ VR + H+ ++SV F+ D IVS S D +
Sbjct 135 NFNPPSNLIVSGSFDETIRIWEVKTGKCVRMIKAHSMPISSVHFNRDGSLIVSASHDGSC 194
Query 153 RLWNTL-ADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTNL 211
++W+ C T+ + + + VS +FSP+ K L+ + D +K+ + T K
Sbjct 195 KIWDAKEGTCLKTLIDDK-SPAVSFAKFSPNGKFILVAT--LDSTLKLSNYATGKFLKVY 251
Query 212 VGHTSVLYTVTVS---PDGSLCASGGKDGVAMLWDVSEGKHLYSLDASC-TINSLCFSPC 267
GHT+ ++ +T + +G SG +D LWD+ L L+ + S+ P
Sbjct 252 TGHTNKVFCITSAFSVTNGKYIVSGSEDNCVYLWDLQARNILQRLEGHTDAVISVSCHPV 311
Query 268 NYWLCAA---TDKSVKIW 282
+ ++ DK+++IW
Sbjct 312 QNEISSSGNHLDKTIRIW 329
> xla:734892 hypothetical protein MGC130867; K03130 transcription
initiation factor TFIID subunit 5
Length=588
Score = 100 bits (250), Expect = 6e-21, Method: Compositional matrix adjust.
Identities = 72/214 (33%), Positives = 109/214 (50%), Gaps = 11/214 (5%)
Query 31 VLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQ 90
+L GH+ V + S+ ++S S D I WNL N TV + GH+ V
Sbjct 336 ILRGHSGPVYRTCFLS-DSSGLLSCSEDTSIRYWNLESYTN--TVLYQ-----GHTYPVW 387
Query 91 DVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDR 150
D+ +S S F S S D+T RLW + +R + H SDV+ + F ++ + +GS D+
Sbjct 388 DLDVSPCSLFFASASHDRTGRLWCFDRTFPLRIYAGHLSDVDCIKFHPNSNYLATGSTDK 447
Query 151 TVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTN 210
TVRLW+T + G H V + FSP+ K + S G D+ +++W L + L
Sbjct 448 TVRLWSTQQGNSVRLFTG-HRGPVLTLAFSPNGK--YLASAGEDQRLRLWDLASGTLYKE 504
Query 211 LVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDV 244
L GHT + ++T SPD +L ASG D +WD+
Sbjct 505 LRGHTDNISSLTFSPDSNLIASGSMDNSVRVWDI 538
Score = 92.0 bits (227), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 69/216 (31%), Positives = 97/216 (44%), Gaps = 5/216 (2%)
Query 73 ETVGFARRALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVN 132
+ G + L GHS V SDS+ LS S D ++R W+L +Q HT V
Sbjct 328 DQAGSEMKILRGHSGPVYRTCFLSDSSGLLSCSEDTSIRYWNLESYTNTVLYQGHTYPVW 387
Query 133 SVAFSADNRQIVSGSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCG 192
+ S + S S DRT RLW I G +D V C++F P+ + +
Sbjct 388 DLDVSPCSLFFASASHDRTGRLWCFDRTFPLRIYAGHLSD-VDCIKFHPNSN--YLATGS 444
Query 193 WDKLVKVWSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYS 252
DK V++WS GH + T+ SP+G AS G+D LWD++ G
Sbjct 445 TDKTVRLWSTQQGNSVRLFTGHRGPVLTLAFSPNGKYLASAGEDQRLRLWDLASGTLYKE 504
Query 253 LDASC-TINSLCFSP-CNYWLCAATDKSVKIWDLEN 286
L I+SL FSP N + D SV++WD+ N
Sbjct 505 LRGHTDNISSLTFSPDSNLIASGSMDNSVRVWDIRN 540
Score = 77.0 bits (188), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 50/145 (34%), Positives = 70/145 (48%), Gaps = 3/145 (2%)
Query 77 FARRALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAF 136
F R GH V + +SN+ +GS DKT+RLW G +VR F H V ++AF
Sbjct 416 FPLRIYAGHLSDVDCIKFHPNSNYLATGSTDKTVRLWSTQQGNSVRLFTGHRGPVLTLAF 475
Query 137 SADNRQIVSGSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKL 196
S + + + S D+ +RLW+ + Y G HTD +S + FSP LI S D
Sbjct 476 SPNGKYLASAGEDQRLRLWDLASGTLYKELRG-HTDNISSLTFSPDSN--LIASGSMDNS 532
Query 197 VKVWSLTTCKLTTNLVGHTSVLYTV 221
V+VW + T G +S L V
Sbjct 533 VRVWDIRNSYCNTPSDGSSSELVGV 557
Score = 45.8 bits (107), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 58/252 (23%), Positives = 101/252 (40%), Gaps = 27/252 (10%)
Query 42 ISTPTVKSNTIISSSRD--KKIIVWNLNDSPNAETVGFARRALTGHSQCVQDVVISSDSN 99
+ TP +++ + +D KK+ + P+ T+ F A Q + IS DS
Sbjct 229 VPTPILQNEAALDQLQDCIKKVK----DGPPSLTTISFY--AFYNTEQLLNAAEISPDSR 282
Query 100 FALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRTVRLWNTLA 159
+G + ++LW L + + H DV+ + + D ++ D A
Sbjct 283 LLAAGFDNSCVKLWSLKSKKL--KAEPHRVDVSRIRLACD---VLEEEEDDQ-------A 330
Query 160 DCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLY 219
+ I G S S ++SC D ++ W+L + T GHT ++
Sbjct 331 GSEMKILRGHSGPVYRTCFLSDSSG---LLSCSEDTSIRYWNLESYTNTVLYQGHTYPVW 387
Query 220 TVTVSPDGSLCASGGKDGVAMLW--DVSEGKHLYSLDASCTINSLCFSP-CNYWLCAATD 276
+ VSP AS D LW D + +Y+ S ++ + F P NY +TD
Sbjct 388 DLDVSPCSLFFASASHDRTGRLWCFDRTFPLRIYAGHLS-DVDCIKFHPNSNYLATGSTD 446
Query 277 KSVKIWDLENKN 288
K+V++W + N
Sbjct 447 KTVRLWSTQQGN 458
> xla:734280 wdr69, MGC85213; WD repeat domain 69
Length=415
Score = 100 bits (248), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 82/293 (27%), Positives = 132/293 (45%), Gaps = 18/293 (6%)
Query 32 LEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQD 91
LEGH + V AI + I + S DK +W+ AET G GH+ +
Sbjct 130 LEGHRNVVYAIQFNNPYGDKIATGSFDKTCKLWS------AET-GKCYHTFRGHTAEIVC 182
Query 92 VVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRT 151
+V + S +GS D T +LWD+ GE T H +++ S++F+ ++++GS D T
Sbjct 183 LVFNPQSTLIATGSMDTTAKLWDIQSGEEALTLSGHAAEIISLSFNTTGDRLITGSFDHT 242
Query 152 VRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTNL 211
V +W + + G H +S +F+ LI + DK K+W K L
Sbjct 243 VSVWEIPSGRRIHTLIG-HRGEISSAQFNWDC--SLIATASMDKSCKLWDSLNGKCVATL 299
Query 212 VGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDA-SCTINSLCF-SPCNY 269
GH + VT G L A+ DG A ++ S K L L+ I+ +CF + N
Sbjct 300 TGHDDEVLDVTFDSTGQLVATASADGTARVYSASSRKCLAKLEGHEGEISKICFNAQGNR 359
Query 270 WLCAATDKSVKIWDLENKNVLDDIHPDQPVKSGIPWCTSLNWSYDGRTLFIGT 322
+ A++DK+ ++WD L Q +K S ++Y+G T+ G+
Sbjct 360 IVTASSDKTSRLWDPHTGECL------QVLKGHTDEIFSCAFNYEGNTIITGS 406
Score = 84.7 bits (208), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 59/244 (24%), Positives = 122/244 (50%), Gaps = 12/244 (4%)
Query 48 KSNTIISSSRDKKI--IVWNLNDSPNAETVG--FARRALTGHSQCVQDVVISSDSNFALS 103
K+ +I++SR +++ ++ L + + + + L H + +V + + ++
Sbjct 50 KAEPLITASRTQQVKQLILRLQEKIGQQDSRQFYLFKVLRAHILPLTNVAFNKSGSSFIT 109
Query 104 GSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSAD-NRQIVSGSRDRTVRLWNT-LADC 161
GS+D+T ++WD GE + T + H + V ++ F+ +I +GS D+T +LW+ C
Sbjct 110 GSYDRTCKVWDTASGEELHTLEGHRNVVYAIQFNNPYGDKIATGSFDKTCKLWSAETGKC 169
Query 162 KYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTNLVGHTSVLYTV 221
+T HT + C+ F +P+ LI + D K+W + + + L GH + + ++
Sbjct 170 YHTFR--GHTAEIVCLVF--NPQSTLIATGSMDTTAKLWDIQSGEEALTLSGHAAEIISL 225
Query 222 TVSPDGSLCASGGKDGVAMLWDVSEGKHLYSL-DASCTINSLCFS-PCNYWLCAATDKSV 279
+ + G +G D +W++ G+ +++L I+S F+ C+ A+ DKS
Sbjct 226 SFNTTGDRLITGSFDHTVSVWEIPSGRRIHTLIGHRGEISSAQFNWDCSLIATASMDKSC 285
Query 280 KIWD 283
K+WD
Sbjct 286 KLWD 289
Score = 59.3 bits (142), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 26/75 (34%), Positives = 44/75 (58%), Gaps = 0/75 (0%)
Query 82 LTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNR 141
L GH + + ++ N ++ S DKT RLWD + GE ++ + HT ++ S AF+ +
Sbjct 341 LEGHEGEISKICFNAQGNRIVTASSDKTSRLWDPHTGECLQVLKGHTDEIFSCAFNYEGN 400
Query 142 QIVSGSRDRTVRLWN 156
I++GS+D T R+W
Sbjct 401 TIITGSKDNTCRIWR 415
> mmu:226182 Taf5, 6330528C20Rik, AV117817; TAF5 RNA polymerase
II, TATA box binding protein (TBP)-associated factor; K03130
transcription initiation factor TFIID subunit 5
Length=801
Score = 99.8 bits (247), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 66/206 (32%), Positives = 95/206 (46%), Gaps = 5/206 (2%)
Query 80 RALTGHSQCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSAD 139
+ L GHS V S D N+ LS S D T+RLW L + ++ H V FS
Sbjct 538 KILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPY 597
Query 140 NRQIVSGSRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKV 199
VSG DR RLW T I G D V+C RF P+ + + D+ V++
Sbjct 598 GYYFVSGGHDRVARLWATDHYQPLRIFAGHLAD-VNCTRFHPNSN--YVATGSADRTVRL 654
Query 200 WSLTTCKLTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASC-T 258
W + GH ++++T SP+G A+G DG +LWD+ G + L T
Sbjct 655 WDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDT 714
Query 259 INSLCFSPCNYWLCAAT-DKSVKIWD 283
+ SL FS L + + D +V++WD
Sbjct 715 VCSLRFSRDGEILASGSMDNTVRLWD 740
Score = 90.1 bits (222), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 65/214 (30%), Positives = 100/214 (46%), Gaps = 11/214 (5%)
Query 31 VLEGHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQ 90
+L GH+ V S + N ++SSS D + +W+L VG+ GH+ V
Sbjct 539 ILYGHSGPVYGASF-SPDRNYLLSSSEDGTVRLWSLQTF--TCLVGY-----KGHNYPVW 590
Query 91 DVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDR 150
D S + +SG D+ RLW + + +R F H +DVN F ++ + +GS DR
Sbjct 591 DTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADR 650
Query 151 TVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTN 210
TVRLW+ L I G H + + FSP+ + + + D V +W + +
Sbjct 651 TVRLWDVLNGNCVRIFTG-HKGPIHSLTFSPNGR--FLATGATDGRVLLWDIGHGLMVGE 707
Query 211 LVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDV 244
L GHT + ++ S DG + ASG D LWD
Sbjct 708 LKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDA 741
Score = 68.9 bits (167), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 63/249 (25%), Positives = 105/249 (42%), Gaps = 11/249 (4%)
Query 89 VQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSR 148
++ V +SD + S D R+ D ++ H+ V +FS D ++S S
Sbjct 505 LRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSE 564
Query 149 DRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLT 208
D TVRLW +L + H V +FSP VS G D++ ++W+ +
Sbjct 565 DGTVRLW-SLQTFTCLVGYKGHNYPVWDTQFSPYGY--YFVSGGHDRVARLWATDHYQPL 621
Query 209 TNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDA-SCTINSLCFSPC 267
GH + + P+ + A+G D LWDV G + I+SL FSP
Sbjct 622 RIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPN 681
Query 268 NYWLC-AATDKSVKIWDLENKNVLDDIHPDQPVKSGIPWCTSLNWSYDGRTLFIGTTSGN 326
+L ATD V +WD+ + ++ ++ K SL +S DG L G+
Sbjct 682 GRFLATGATDGRVLLWDIGHGLMVGEL------KGHTDTVCSLRFSRDGEILASGSMDNT 735
Query 327 IHVYEVAEG 335
+ +++ +
Sbjct 736 VRLWDAVKA 744
Score = 67.4 bits (163), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 66/252 (26%), Positives = 104/252 (41%), Gaps = 24/252 (9%)
Query 87 QCVQDVVISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSG 146
Q + V ++ DS+ G D T+R+W + + SV ++D I
Sbjct 472 QGLTAVDVTDDSSLIAGGFADSTVRVWSVT-----------PKKLRSVKQASDLSLIDKE 520
Query 147 SRDRTVRLWNTLADCKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCK 206
S D R+ + + I G H+ V FSP ++S D V++WSL T
Sbjct 521 SDDVLERIMDEKTASELKILYG-HSGPVYGASFSPDRN--YLLSSSEDGTVRLWSLQTFT 577
Query 207 LTTNLVGHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASCT-INSLCFS 265
GH ++ SP G SGG D VA LW + L +N F
Sbjct 578 CLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFH 637
Query 266 P-CNYWLCAATDKSVKIWDLENKNVLDDIHPDQ-PVKSGIPWCTSLNWSYDGRTLFIGTT 323
P NY + D++V++WD+ N N + + P+ S L +S +GR L G T
Sbjct 638 PNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHS-------LTFSPNGRFLATGAT 690
Query 324 SGNIHVYEVAEG 335
G + ++++ G
Sbjct 691 DGRVLLWDIGHG 702
Score = 61.6 bits (148), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 35/110 (31%), Positives = 55/110 (50%), Gaps = 7/110 (6%)
Query 49 SNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQDVVISSDSNFALSGSWDK 108
SN + + S D+ + +W++ + G R TGH + + S + F +G+ D
Sbjct 640 SNYVATGSADRTVRLWDVLN-------GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDG 692
Query 109 TLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRTVRLWNTL 158
+ LWD+ G V + HT V S+ FS D + SGS D TVRLW+ +
Sbjct 693 RVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAV 742
> hsa:10300 KATNB1, KAT; katanin p80 (WD repeat containing) subunit
B 1
Length=655
Score = 99.8 bits (247), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 66/260 (25%), Positives = 122/260 (46%), Gaps = 13/260 (5%)
Query 34 GHTDWVTAISTPTVKSNTIISSSRDKKIIVWNLNDSPNAETVGFARRALTGHSQCVQDVV 93
H V+++ + + D ++ +W++N PN +LTGH+ V+ V
Sbjct 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSIN-KPNCIM------SLTGHTSPVESVR 70
Query 94 ISSDSNFALSGSWDKTLRLWDLNVGETVRTFQKHTSDVNSVAFSADNRQIVSGSRDRTVR 153
+++ ++GS ++R+WDL + +RT H +++ S+ F + SGS+D ++
Sbjct 71 LNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIK 130
Query 154 LWNTLAD-CKYTIEEGQHTDWVSCVRFSPSPKEPLIVSCGWDKLVKVWSLTTCKLTTNLV 212
LW+ C + H+ V C+RFSP K + S D VK+W LT K+ +
Sbjct 131 LWDIRRKGCVFRYR--GHSQAVRCLRFSPDGK--WLASAADDHTVKLWDLTAGKMMSEFP 186
Query 213 GHTSVLYTVTVSPDGSLCASGGKDGVAMLWDVSEGKHLYSLDASC-TINSLCFSPCNYWL 271
GHT + V P+ L ASG D WD+ + + + ++ + S+ F+P L
Sbjct 187 GHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCL 246
Query 272 CAATDKSVKIWDLENKNVLD 291
+ S++++ E + D
Sbjct 247 YSGCQDSLRVYGWEPERCFD 266
Lambda K H
0.318 0.131 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 14093301480
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
Posted date: Sep 17, 2011 2:57 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40