bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
164,496 sequences; 82,071,388 total letters
Query= Eten_0897_orf1
Length=202
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_119920 dihydrolipoamide branched chain transacylase... 265 5e-71
pfa:PFC0170c dihydrolipoamide acyltransferase, putative (EC:2.... 167 2e-41
xla:447616 dbt, MGC85493; dihydrolipoamide branched chain tran... 166 5e-41
mmu:13171 Dbt, D3Wsu60e; dihydrolipoamide branched chain trans... 156 4e-38
tpv:TP04_0457 lipoamide transferase (EC:2.3.1.-); K09699 2-oxo... 156 6e-38
ath:AT3G06850 BCE2; BCE2; acetyltransferase/ alpha-ketoacid de... 155 7e-38
hsa:1629 DBT, BCATE2, E2, E2B, MGC9061; dihydrolipoamide branc... 155 7e-38
dre:541388 dbt, im:7147214, zgc:103768; dihydrolipoamide branc... 155 1e-37
cel:ZK669.4 hypothetical protein; K09699 2-oxoisovalerate dehy... 150 3e-36
bbo:BBOV_II001300 18.m06098; lipoamide acyltransferase compone... 146 4e-35
sce:YDR148C KGD2; Dihydrolipoyl transsuccinylase, component of... 99.4 8e-21
hsa:1743 DLST, DLTS; dihydrolipoamide S-succinyltransferase (E... 97.1 4e-20
cel:W02F12.5 hypothetical protein; K00658 2-oxoglutarate dehyd... 96.3 6e-20
mmu:78920 Dlst, 1600017E01Rik, 4632413C10Rik, 4930529O08Rik, D... 96.3 7e-20
sce:YNL071W LAT1, ODP2, PDA2; Dihydrolipoamide acetyltransfera... 94.7 2e-19
dre:324201 dlat, wu:fc14f10, wu:fc21f08, wu:fc86g11, wu:fj57d0... 92.8 6e-19
bbo:BBOV_IV004840 23.m06243; dihydrolipoamide succinyltransfer... 92.0 1e-18
xla:380395 dlst, MGC53142; dihydrolipoamide S-succinyltransfer... 91.3 2e-18
eco:b0727 sucB, ECK0715, JW0716; dihydrolipoyltranssuccinase (... 90.5 4e-18
dre:368262 dlst, cb60, wu:fc39d01; dihydrolipoamide S-succinyl... 90.1 4e-18
pfa:PF13_0121 dihydrolipamide succinyltransferase component of... 90.1 5e-18
eco:b0115 aceF, ECK0114, JW0111; pyruvate dehydrogenase, dihyd... 89.4 8e-18
xla:447247 pdhx, MGC86218; pyruvate dehydrogenase complex, com... 88.6 1e-17
xla:398314 dlat; dihydrolipoamide S-acetyltransferase (EC:2.3.... 88.2 2e-17
hsa:8050 PDHX, DLDBP, E3BP, OPDX, PDX1, proX; pyruvate dehydro... 86.7 5e-17
ath:AT1G54220 dihydrolipoamide S-acetyltransferase, putative (... 84.3 2e-16
mmu:27402 Pdhx, AI481367, E3bp, Pdx1; pyruvate dehydrogenase c... 84.3 3e-16
cel:F23B12.5 hypothetical protein; K00627 pyruvate dehydrogena... 84.0 3e-16
tgo:TGME49_006610 biotin requiring domain-containing protein /... 84.0 3e-16
ath:AT3G13930 dihydrolipoamide S-acetyltransferase, putative (... 83.2 5e-16
mmu:235339 Dlat, 6332404G05Rik, DLTA, PDC-E2; dihydrolipoamide... 82.8 8e-16
ath:AT3G25860 LTA2; LTA2; dihydrolipoyllysine-residue acetyltr... 82.4 9e-16
tgo:TGME49_019550 dihydrolipoamide succinyltransferase compone... 79.7 6e-15
hsa:1737 DLAT, DLTA, PDC-E2, PDCE2; dihydrolipoamide S-acetylt... 79.3 9e-15
cel:C30H6.7 hypothetical protein; K00627 pyruvate dehydrogenas... 77.4 3e-14
tpv:TP01_0262 dihydrolipoamide succinyltransferase; K00658 2-o... 77.0 4e-14
dre:393532 pdhx, MGC66110, zgc:66110, zgc:85977; pyruvate dehy... 75.9 9e-14
ath:AT1G34430 EMB3003 (embryo defective 3003); acyltransferase... 72.0 1e-12
ath:AT5G55070 2-oxoacid dehydrogenase family protein (EC:2.3.1... 70.9 3e-12
ath:AT3G52200 LTA3; LTA3; ATP binding / dihydrolipoyllysine-re... 68.9 1e-11
ath:AT4G26910 2-oxoacid dehydrogenase family protein (EC:2.3.1... 67.4 3e-11
pfa:PF10_0407 dihydrolipoamide acyltransferase, putative (EC:2... 45.1 2e-04
ath:AT5G44950 F-box family protein 31.6 1.7
tgo:TGME49_106660 RNA pseudouridine synthase domain containing... 31.2 2.2
ath:AT1G79950 helicase-related; K11136 regulator of telomere e... 31.2 2.7
sce:YGR227W DIE2, ALG10; Die2p (EC:2.4.1.-); K03850 alpha-1,2-... 30.8 3.5
> tgo:TGME49_119920 dihydrolipoamide branched chain transacylase,
E2 subunit, putative (EC:2.3.1.168); K09699 2-oxoisovalerate
dehydrogenase E2 component (dihydrolipoyl transacylase)
[EC:2.3.1.168]
Length=510
Score = 265 bits (678), Expect = 5e-71, Method: Compositional matrix adjust.
Identities = 125/190 (65%), Positives = 155/190 (81%), Gaps = 1/190 (0%)
Query 13 NIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAIDSPGGLVVPCVK 72
N R ++TAFLIKA+SLA++E PI+NSKFN T +SYT+FGSHN+SVAID+P GLVVP +K
Sbjct 322 NCRPTITAFLIKAVSLALDETPILNSKFNAATGDSYTQFGSHNISVAIDTPNGLVVPNIK 381
Query 73 NVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYIHPLLFDGQAVI 132
NVQDL ++EIQ EL RLQ LA AN+LSPADL GGTI++SNVGVISGTY+H LLFDGQA I
Sbjct 382 NVQDLNVLEIQAELHRLQELATANKLSPADLQGGTISISNVGVISGTYVHALLFDGQACI 441
Query 133 VGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATITRFSKSIKNLLE 192
+GVG+ + LPRFV + +E R I+ C+F+ADHRHCDGAT+ RF+K +K LLE
Sbjct 442 IGVGQARDLPRFV-GKSGQAFDEDLVERRRIMTCAFTADHRHCDGATVARFNKRVKELLE 500
Query 193 NPALMLVHLR 202
NPA+ML+HLR
Sbjct 501 NPAMMLLHLR 510
> pfa:PFC0170c dihydrolipoamide acyltransferase, putative (EC:2.3.1.-);
K09699 2-oxoisovalerate dehydrogenase E2 component
(dihydrolipoyl transacylase) [EC:2.3.1.168]
Length=448
Score = 167 bits (423), Expect = 2e-41, Method: Compositional matrix adjust.
Identities = 83/189 (43%), Positives = 130/189 (68%), Gaps = 2/189 (1%)
Query 7 KELASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAIDSPGGL 66
K L ++ I++T LIK IS + E+PI+NSKFN +T N+YT + +HN+S+A+D+P GL
Sbjct 255 KNLQTKETNITITCILIKLISNVLKEFPILNSKFNFKT-NTYTMYKNHNISIAVDTPHGL 313
Query 67 VVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYIHPLLF 126
+VP +KNVQ+ +++IQ++L+ L+ A +L +D+T GTI +SN G ISGT+ P++F
Sbjct 314 LVPNIKNVQNKNILDIQKDLLSLRDKANNMQLDKSDITNGTITVSNFGAISGTFATPIVF 373
Query 127 DGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATITRFSKS 186
D QA I+G+G++++ D ++ N L A D +N +F ADHR+ DGAT+ +FSK
Sbjct 374 DNQACIIGIGKMEKKLLLKDESNNLNSLNDILVA-DTINFTFGADHRYIDGATLAQFSKM 432
Query 187 IKNLLENPA 195
+K +EN A
Sbjct 433 LKMNIENCA 441
> xla:447616 dbt, MGC85493; dihydrolipoamide branched chain transacylase
E2 (EC:2.3.1.168); K09699 2-oxoisovalerate dehydrogenase
E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168]
Length=492
Score = 166 bits (420), Expect = 5e-41, Method: Compositional matrix adjust.
Identities = 91/202 (45%), Positives = 127/202 (62%), Gaps = 9/202 (4%)
Query 1 LRHALNKELASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAI 60
LR L S+ +R+S F +KA SL + ++PI+NS + QN T +HN+ +A+
Sbjct 300 LREELKPLAESRGVRLSFMPFFLKAASLGLVQFPILNSSVDENCQN-ITYKAAHNIGIAM 358
Query 61 DSPGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTY 120
D+ GLVVP VKN+Q ++ EI EL RLQ L +L DLTGGT LSN+G I GTY
Sbjct 359 DTQQGLVVPNVKNIQVRSIFEIAAELNRLQSLGSTGQLGATDLTGGTFTLSNIGSIGGTY 418
Query 121 IHPLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATI 180
P++ + I +G+VQ LPRF DS G+ ++A+ I+N S+SADHR DGAT+
Sbjct 419 AKPVILPPEVAIGAIGKVQVLPRF----DSKGQ---VVKAQ-IINISWSADHRIIDGATM 470
Query 181 TRFSKSIKNLLENPALMLVHLR 202
+RFS K+ LENP+LML+ L+
Sbjct 471 SRFSNLWKSYLENPSLMLLELK 492
> mmu:13171 Dbt, D3Wsu60e; dihydrolipoamide branched chain transacylase
E2 (EC:2.3.1.168); K09699 2-oxoisovalerate dehydrogenase
E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168]
Length=482
Score = 156 bits (395), Expect = 4e-38, Method: Compositional matrix adjust.
Identities = 86/202 (42%), Positives = 123/202 (60%), Gaps = 9/202 (4%)
Query 1 LRHALNKELASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAI 60
LR L ++ I++S F +KA SL + ++PI+N+ + QN T SHN+ +A+
Sbjct 290 LREELKPVALARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQN-ITYKASHNIGIAM 348
Query 61 DSPGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTY 120
D+ GL+VP VKNVQ ++ EI EL RLQ L + +L DLTGGT LSN+G I GTY
Sbjct 349 DTELGLIVPNVKNVQVRSVFEIAMELNRLQKLGSSGQLGTTDLTGGTFTLSNIGSIGGTY 408
Query 121 IHPLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATI 180
P++ + I +G ++ LPRF +K +A+ I+N S+SADHR DGAT+
Sbjct 409 AKPVILPPEVAIGALGAIKALPRF-------DQKGDVYKAQ-IMNVSWSADHRVIDGATM 460
Query 181 TRFSKSIKNLLENPALMLVHLR 202
+RFS K+ LENPA ML+ L+
Sbjct 461 SRFSNLWKSYLENPAFMLLDLK 482
> tpv:TP04_0457 lipoamide transferase (EC:2.3.1.-); K09699 2-oxoisovalerate
dehydrogenase E2 component (dihydrolipoyl transacylase)
[EC:2.3.1.168]
Length=420
Score = 156 bits (394), Expect = 6e-38, Method: Compositional matrix adjust.
Identities = 85/190 (44%), Positives = 119/190 (62%), Gaps = 15/190 (7%)
Query 15 RISLTAFLIKAISLAINEYPIVNSKFNT----ETQNSYTEFGSHNVSVAIDSPGGLVVPC 70
+I++T F+IK+ISLA+ + PI+NSKFN+ + +SY + +HN+SVAI++ GL+VP
Sbjct 227 KITITPFIIKSISLALEKVPIINSKFNSTNTGKGPSSYFLYKNHNISVAINTKNGLMVPN 286
Query 71 VKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYIHPLLFDGQA 130
+KNV LT+ EIQREL LQ A L+ D+ GGT LSN+G + GT++ LFDGQA
Sbjct 287 IKNVNKLTIREIQRELTSLQQKANTKTLTFNDIKGGTCTLSNLGSLGGTFVKARLFDGQA 346
Query 131 VIVGVGR-------VQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATITRF 183
I+ GR + + P+ DS + TLE R I N +ADHRH DGA IT F
Sbjct 347 AIIAFGRSIQRVVPISKAPK----TDSTNLDDYTLECRSICNIGVTADHRHIDGAIITTF 402
Query 184 SKSIKNLLEN 193
+K+ L+N
Sbjct 403 ISHLKHFLQN 412
> ath:AT3G06850 BCE2; BCE2; acetyltransferase/ alpha-ketoacid
dehydrogenase/ dihydrolipoamide branched chain acyltransferase
(EC:2.3.1.168); K09699 2-oxoisovalerate dehydrogenase E2
component (dihydrolipoyl transacylase) [EC:2.3.1.168]
Length=483
Score = 155 bits (393), Expect = 7e-38, Method: Compositional matrix adjust.
Identities = 82/202 (40%), Positives = 123/202 (60%), Gaps = 9/202 (4%)
Query 1 LRHALNKELASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAI 60
L+ + I+ + LIK++S+A+ +YP VNS FN E+ + GSHN+ VA+
Sbjct 291 LKQFFKENNTDSTIKHTFLPTLIKSLSMALTKYPFVNSCFNAESLEIILK-GSHNIGVAM 349
Query 61 DSPGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTY 120
+ GLVVP +KNVQ L+L+EI +EL RLQ LA N+L+P D+TGGTI LSN+G I G +
Sbjct 350 ATEHGLVVPNIKNVQSLSLLEITKELSRLQHLAANNKLNPEDVTGGTITLSNIGAIGGKF 409
Query 121 IHPLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATI 180
PLL + I+ +GR++++P+F K T+ I+ + +ADHR DGAT+
Sbjct 410 GSPLLNLPEVAIIALGRIEKVPKF--------SKEGTVYPASIMMVNIAADHRVLDGATV 461
Query 181 TRFSKSIKNLLENPALMLVHLR 202
RF K +E P L+++ +R
Sbjct 462 ARFCCQWKEYVEKPELLMLQMR 483
> hsa:1629 DBT, BCATE2, E2, E2B, MGC9061; dihydrolipoamide branched
chain transacylase E2 (EC:2.3.1.168); K09699 2-oxoisovalerate
dehydrogenase E2 component (dihydrolipoyl transacylase)
[EC:2.3.1.168]
Length=482
Score = 155 bits (393), Expect = 7e-38, Method: Compositional matrix adjust.
Identities = 84/202 (41%), Positives = 124/202 (61%), Gaps = 9/202 (4%)
Query 1 LRHALNKELASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAI 60
LR L ++ I++S F +KA SL + ++PI+N+ + QN T SHN+ +A+
Sbjct 290 LREELKPIAFARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQN-ITYKASHNIGIAM 348
Query 61 DSPGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTY 120
D+ GL+VP VKNVQ ++ +I EL RLQ L ++LS DLTGGT LSN+G I GT+
Sbjct 349 DTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVSQLSTTDLTGGTFTLSNIGSIGGTF 408
Query 121 IHPLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATI 180
P++ + I +G ++ +PRF +K +A+ I+N S+SADHR DGAT+
Sbjct 409 AKPVIMPPEVAIGALGSIKAIPRF-------NQKGEVYKAQ-IMNVSWSADHRVIDGATM 460
Query 181 TRFSKSIKNLLENPALMLVHLR 202
+RFS K+ LENPA ML+ L+
Sbjct 461 SRFSNLWKSYLENPAFMLLDLK 482
> dre:541388 dbt, im:7147214, zgc:103768; dihydrolipoamide branched
chain transacylase E2 (EC:2.3.1.168); K09699 2-oxoisovalerate
dehydrogenase E2 component (dihydrolipoyl transacylase)
[EC:2.3.1.168]
Length=493
Score = 155 bits (391), Expect = 1e-37, Method: Compositional matrix adjust.
Identities = 87/202 (43%), Positives = 125/202 (61%), Gaps = 9/202 (4%)
Query 1 LRHALNKELASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAI 60
LR L S+ +++S F IKA SLA+ +PI+NS + E S T +HN+ +A+
Sbjct 301 LRSELKGLTESRGVKLSYMPFFIKAASLALLHFPILNSSLD-ENCTSITYKAAHNIGLAM 359
Query 61 DSPGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTY 120
D+ GL+VP VKN+Q L++ EI EL RLQ L + +L +DLTGGT LSN+G I GTY
Sbjct 360 DTSQGLLVPNVKNIQMLSVFEIAVELNRLQILGASGQLGTSDLTGGTFTLSNIGSIGGTY 419
Query 121 IHPLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATI 180
P++ + I +G++Q LPRF K+ ++A I+N S+SADHR DGAT+
Sbjct 420 AKPVILPPEVAIGALGKIQVLPRF-------NHKDEVVKAH-IMNVSWSADHRIIDGATM 471
Query 181 TRFSKSIKNLLENPALMLVHLR 202
RFS ++ LENPA M++ L+
Sbjct 472 CRFSNLWRSYLENPASMVLDLK 493
> cel:ZK669.4 hypothetical protein; K09699 2-oxoisovalerate dehydrogenase
E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168]
Length=448
Score = 150 bits (378), Expect = 3e-36, Method: Compositional matrix adjust.
Identities = 81/197 (41%), Positives = 120/197 (60%), Gaps = 10/197 (5%)
Query 7 KELASQ-NIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAIDSPGG 65
KE A + +I++S F IKA SLA+ EYP +NS + + +N + SHN+ +A+D+PGG
Sbjct 261 KEFAKERHIKLSYMPFFIKAASLALLEYPSLNSTTDEKMENVIHK-ASHNICLAMDTPGG 319
Query 66 LVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYIHPLL 125
LVVP +KN + ++ EI +EL RL K ++ DL GT +LSN+G I GTY P++
Sbjct 320 LVVPNIKNCEQRSIFEIAQELNRLLEAGKKQQIKREDLIDGTFSLSNIGNIGGTYASPVV 379
Query 126 FDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATITRFSK 185
F Q I +G++++LPRF K+ + +I+ S+ ADHR DGAT+ RFS
Sbjct 380 FPPQVAIGAIGKIEKLPRF--------DKHDNVIPVNIMKVSWCADHRVVDGATMARFSN 431
Query 186 SIKNLLENPALMLVHLR 202
K LE+P+ ML L+
Sbjct 432 RWKFYLEHPSAMLAQLK 448
> bbo:BBOV_II001300 18.m06098; lipoamide acyltransferase component
of branched-chain alpha-keto acid dehydrogenase complex
(EC:2.3.1.12); K09699 2-oxoisovalerate dehydrogenase E2 component
(dihydrolipoyl transacylase) [EC:2.3.1.168]
Length=417
Score = 146 bits (369), Expect = 4e-35, Method: Compositional matrix adjust.
Identities = 81/198 (40%), Positives = 122/198 (61%), Gaps = 12/198 (6%)
Query 3 HALNKELASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAIDS 62
+ L K +I++++T FL+KA SLA++E PI+NSKF + Y + HN++VA+ +
Sbjct 231 YYLQKRALETDIKLTMTPFLLKAFSLALSENPIMNSKFKG---DGYIAYKEHNINVAVAT 287
Query 63 PGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYIH 122
GL+VP ++NV+ ++ E+Q +L R+Q LA RLSP D++GGT LSN+G I GT+++
Sbjct 288 DHGLLVPVIRNVESKSIRELQVDLARVQRLAAEMRLSPGDMSGGTATLSNLGAIGGTHVN 347
Query 123 PLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATITR 182
LFDGQ IV G ++ P +V E L RDI +ADHRH DGA I R
Sbjct 348 ARLFDGQGTIVAFGAARKTPCYVGDE---------LVPRDIACLGVTADHRHIDGAAIAR 398
Query 183 FSKSIKNLLENPALMLVH 200
F+ ++K L++ + VH
Sbjct 399 FAAALKRYLQDVSNFDVH 416
> sce:YDR148C KGD2; Dihydrolipoyl transsuccinylase, component
of the mitochondrial alpha-ketoglutarate dehydrogenase complex,
which catalyzes the oxidative decarboxylation of alpha-ketoglutarate
to succinyl-CoA in the TCA cycle; phosphorylated
(EC:2.3.1.61); K00658 2-oxoglutarate dehydrogenase E2 component
(dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
Length=463
Score = 99.4 bits (246), Expect = 8e-21, Method: Compositional matrix adjust.
Identities = 58/185 (31%), Positives = 99/185 (53%), Gaps = 12/185 (6%)
Query 15 RISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAIDSPGGLVVPCVKNV 74
+ KA +LA + P VN + Q Y ++ ++SVA+ +P GLV P V+N
Sbjct 290 KFGFMGLFSKACTLAAKDIPAVNGAIEGD-QIVYRDY--TDISVAVATPKGLVTPVVRNA 346
Query 75 QDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYIHPLLFDGQAVIVG 134
+ L++++I+ E+VRL A+ +L+ D+TGGT +SN GV Y P++ Q ++G
Sbjct 347 ESLSVLDIENEIVRLSHKARDGKLTLEDMTGGTFTISNGGVFGSLYGTPIINSPQTAVLG 406
Query 135 VGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATITRFSKSIKNLLENP 194
+ V++ P V N + +R ++ + + DHR DG F K++K L+E+P
Sbjct 407 LHGVKERPVTV---------NGQIVSRPMMYLALTYDHRLLDGREAVTFLKTVKELIEDP 457
Query 195 ALMLV 199
ML+
Sbjct 458 RKMLL 462
> hsa:1743 DLST, DLTS; dihydrolipoamide S-succinyltransferase
(E2 component of 2-oxo-glutarate complex) (EC:2.3.1.61); K00658
2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide
succinyltransferase) [EC:2.3.1.61]
Length=453
Score = 97.1 bits (240), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 58/202 (28%), Positives = 107/202 (52%), Gaps = 14/202 (6%)
Query 3 HALNKE--LASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNS-YTEFGSHNVSVA 59
A +KE L N+++ + +KA + A+ E P+VN+ + T+ Y ++ ++SVA
Sbjct 263 RARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVYRDY--IDISVA 320
Query 60 IDSPGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGT 119
+ +P GLVVP ++NV+ + +I+R + L A+ N L+ D+ GGT +SN GV
Sbjct 321 VATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVFGSL 380
Query 120 YIHPLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGAT 179
+ P++ Q+ I+G+ + P + + +E R ++ + + DHR DG
Sbjct 381 FGTPIINPPQSAILGMHGIFDRPVAIGGK---------VEVRPMMYVALTYDHRLIDGRE 431
Query 180 ITRFSKSIKNLLENPALMLVHL 201
F + IK +E+P ++L+ L
Sbjct 432 AVTFLRKIKAAVEDPRVLLLDL 453
> cel:W02F12.5 hypothetical protein; K00658 2-oxoglutarate dehydrogenase
E2 component (dihydrolipoamide succinyltransferase)
[EC:2.3.1.61]
Length=463
Score = 96.3 bits (238), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 61/202 (30%), Positives = 106/202 (52%), Gaps = 13/202 (6%)
Query 1 LRHALNKE-LASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVA 59
+R K+ +A +++ + + ++A + A+ E P+VN+ + E + Y F ++SVA
Sbjct 274 MRKTYQKDFVAKHGVKLGMMSPFVRAAAYALQESPVVNAVLD-ENEIVYRHF--VDISVA 330
Query 60 IDSPGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGT 119
+ +P GLVVP ++NV+ + +I+ EL L A+ +L+ D+ GGT +SN GV
Sbjct 331 VATPKGLVVPVLRNVESMNYAQIELELANLGVKARDGKLAVEDMEGGTFTISNGGVFGSM 390
Query 120 YIHPLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGAT 179
+ P++ Q+ I+G+ V R V N E R I+ + + DHR DG
Sbjct 391 FGTPIINPPQSAILGMHGV--FDRVVPV-------NGKPEIRPIMQIALTYDHRLIDGRE 441
Query 180 ITRFSKSIKNLLENPALMLVHL 201
F K IK +E+P +M ++L
Sbjct 442 AVTFLKKIKTAVEDPRIMFMNL 463
> mmu:78920 Dlst, 1600017E01Rik, 4632413C10Rik, 4930529O08Rik,
DLTS; dihydrolipoamide S-succinyltransferase (E2 component
of 2-oxo-glutarate complex) (EC:2.3.1.61); K00658 2-oxoglutarate
dehydrogenase E2 component (dihydrolipoamide succinyltransferase)
[EC:2.3.1.61]
Length=454
Score = 96.3 bits (238), Expect = 7e-20, Method: Compositional matrix adjust.
Identities = 56/194 (28%), Positives = 103/194 (53%), Gaps = 12/194 (6%)
Query 9 LASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNS-YTEFGSHNVSVAIDSPGGLV 67
L N+++ + +KA + A+ E P+VN+ + T+ Y ++ ++SVA+ +P GLV
Sbjct 272 LKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDATKEVVYRDY--IDISVAVATPRGLV 329
Query 68 VPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYIHPLLFD 127
VP ++NV+ + +I+R + L A+ N L+ D+ GGT +SN GV + P++
Sbjct 330 VPVIRNVETMNYADIERTINELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINP 389
Query 128 GQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATITRFSKSI 187
Q+ I+G+ + P V + +E R ++ + + DHR DG F + I
Sbjct 390 PQSAILGMHAIFDRPVAVGGK---------VEVRPMMYVALTYDHRLIDGREAVTFLRKI 440
Query 188 KNLLENPALMLVHL 201
K +E+P ++L+ L
Sbjct 441 KAAVEDPRVLLLDL 454
> sce:YNL071W LAT1, ODP2, PDA2; Dihydrolipoamide acetyltransferase
component (E2) of pyruvate dehydrogenase complex, which
catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA
(EC:2.3.1.12); K00627 pyruvate dehydrogenase E2 component
(dihydrolipoamide acetyltransferase) [EC:2.3.1.12]
Length=482
Score = 94.7 bits (234), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 62/200 (31%), Positives = 109/200 (54%), Gaps = 9/200 (4%)
Query 1 LRHALNKELASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAI 60
LR +LN A+ ++S+ L+KAI++A P N+ + +N +F + +VSVA+
Sbjct 291 LRQSLNA-TANDKYKLSINDLLVKAITVAAKRVPDANA-YWLPNENVIRKFKNVDVSVAV 348
Query 61 DSPGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTY 120
+P GL+ P VKN + L +I E+ L A+ N+L+P + GGTI +SN+G+ +
Sbjct 349 ATPTGLLTPIVKNCEAKGLSQISNEIKELVKRARINKLAPEEFQGGTICISNMGMNNAVN 408
Query 121 IHPLLFD-GQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGAT 179
+ + + Q+ I+ + V++ V ED+ + + + + + +F DHR DGA
Sbjct 409 MFTSIINPPQSTILAIATVER----VAVEDAAAENGFSFDNQVTITGTF--DHRTIDGAK 462
Query 180 ITRFSKSIKNLLENPALMLV 199
F K +K ++ENP ML+
Sbjct 463 GAEFMKELKTVIENPLEMLL 482
> dre:324201 dlat, wu:fc14f10, wu:fc21f08, wu:fc86g11, wu:fj57d06;
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate
dehydrogenase complex) (EC:2.3.1.12); K00627 pyruvate
dehydrogenase E2 component (dihydrolipoamide acetyltransferase)
[EC:2.3.1.12]
Length=652
Score = 92.8 bits (229), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 60/201 (29%), Positives = 103/201 (51%), Gaps = 14/201 (6%)
Query 1 LRHALNKELASQNIRISLTAFLIKAISLAINEYPIVNSKFNTET--QNSYTEFGSHNVSV 58
LR LN E+ ++NI++S+ F+IKA +LA + P NS + QN +VSV
Sbjct 464 LRKELNAEVKAENIKLSVNDFIIKASALACLKVPEANSSWMDTVIRQNHVV-----DVSV 518
Query 59 AIDSPGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISG 118
A+ +P GL+ P V N L I +++ L A+ +L P + GGT +SN+G+
Sbjct 519 AVSTPVGLITPIVFNAHIKGLANISKDVSALAAKARDGKLQPHEFQGGTFTISNLGMYGI 578
Query 119 TYIHPLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGA 178
+ ++ QA I+ VG ++ R + +++ G + ++++ + S DHR DGA
Sbjct 579 KHFSAIINPPQACILAVGGSEK--RLLPADNEKG-----FDVANMMSVTLSCDHRVVDGA 631
Query 179 TITRFSKSIKNLLENPALMLV 199
++ + LE P ML+
Sbjct 632 VGAQWLAEFRKFLEKPFTMLL 652
> bbo:BBOV_IV004840 23.m06243; dihydrolipoamide succinyltransferase
(EC:2.3.1.61); K00658 2-oxoglutarate dehydrogenase E2
component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
Length=402
Score = 92.0 bits (227), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 62/198 (31%), Positives = 107/198 (54%), Gaps = 13/198 (6%)
Query 1 LRHALNKELASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAI 60
LR LN E +++ + +KA ++A+ + PI+NS E + T+ ++SVA+
Sbjct 216 LRKELN-ESGKYPVKLGYVSAYMKASTMALLKMPIMNSYI--EGDDIVTKHFV-DISVAV 271
Query 61 DSPGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTY 120
+P GLVVP ++N + + +E++++LV + RL+ AD+TGGT +SN GV
Sbjct 272 ATPTGLVVPVIRNCEGKSWIELEQQLVDAAAKGREGRLTVADMTGGTFTISNGGVYGSVL 331
Query 121 IHPLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATI 180
P++ Q+ I+G+ + + R V +D + R I+N + S DHR DG
Sbjct 332 STPIINPPQSSILGMHSI--IKRCVVRDDQ-------MVIRPIMNLALSYDHRLIDGREA 382
Query 181 TRFSKSIKNLLENPALML 198
+F +IK +ENP ++L
Sbjct 383 VQFLIAIKEAIENPKVLL 400
> xla:380395 dlst, MGC53142; dihydrolipoamide S-succinyltransferase
(E2 component of 2-oxo-glutarate complex) (EC:2.3.1.61);
K00658 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide
succinyltransferase) [EC:2.3.1.61]
Length=452
Score = 91.3 bits (225), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 56/194 (28%), Positives = 102/194 (52%), Gaps = 12/194 (6%)
Query 9 LASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQN-SYTEFGSHNVSVAIDSPGGLV 67
L +++ + +KA + A+ + P VN+ + T+ Y ++ ++SVA+ +P GLV
Sbjct 270 LKKHGLKLGFMSAFVKASAFALQDQPAVNAVIDDTTKEIVYRDY--IDISVAVSTPRGLV 327
Query 68 VPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYIHPLLFD 127
VP ++NV+ + I+R + L A+ N L+ D+ GGT +SN GV + P++
Sbjct 328 VPVLRNVESMNFANIERTITELGEKARKNELAIEDMDGGTFTISNGGVFGSMFGTPIINP 387
Query 128 GQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATITRFSKSI 187
Q+ I+G+ + P V GK +E R ++ + + DHR DG F + I
Sbjct 388 PQSAILGMHGIFDRPVAV-----SGK----VEIRPMMYIALTYDHRLIDGREAVLFLRKI 438
Query 188 KNLLENPALMLVHL 201
K+ +E+P ++L+ L
Sbjct 439 KSAVEDPRVLLLDL 452
> eco:b0727 sucB, ECK0715, JW0716; dihydrolipoyltranssuccinase
(EC:2.3.1.61); K00658 2-oxoglutarate dehydrogenase E2 component
(dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
Length=405
Score = 90.5 bits (223), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 54/188 (28%), Positives = 97/188 (51%), Gaps = 12/188 (6%)
Query 14 IRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAIDSPGGLVVPCVKN 73
IR+ +F +KA+ A+ YP VN+ + + + F +VS+A+ +P GLV P +++
Sbjct 230 IRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYF---DVSMAVSTPRGLVTPVLRD 286
Query 74 VQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYIHPLLFDGQAVIV 133
V L + +I++++ L + +L+ DLTGG ++N GV P++ Q+ I+
Sbjct 287 VDTLGMADIEKKIKELAVKGRDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPPQSAIL 346
Query 134 GVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATITRFSKSIKNLLEN 193
G+ ++ P V N +E ++ + S DHR DG F +IK LLE+
Sbjct 347 GMHAIKDRPMAV---------NGQVEILPMMYLALSYDHRLIDGRESVGFLVTIKELLED 397
Query 194 PALMLVHL 201
P +L+ +
Sbjct 398 PTRLLLDV 405
> dre:368262 dlst, cb60, wu:fc39d01; dihydrolipoamide S-succinyltransferase
(EC:2.3.1.61); K00658 2-oxoglutarate dehydrogenase
E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
Length=458
Score = 90.1 bits (222), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 52/200 (26%), Positives = 104/200 (52%), Gaps = 12/200 (6%)
Query 3 HALNKELASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQN-SYTEFGSHNVSVAID 61
H + L I++ + +KA + A+ + P VN+ + T+ Y ++ ++SVA+
Sbjct 270 HYKDAFLKKHGIKLGFMSAFVKAAAYALTDQPAVNAVIDDTTKEIVYRDY--VDISVAVA 327
Query 62 SPGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYI 121
+P GLVVP ++ V+ + +I++ + L A+ N L+ D+ GGT +SN GV +
Sbjct 328 TPKGLVVPVIRGVEGMNFADIEKTINELGEKARKNELAVEDMDGGTFTISNGGVFGSMFG 387
Query 122 HPLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATIT 181
P++ Q+ I+G+ + P + + +E R ++ + + DHR DG
Sbjct 388 TPIINPPQSAILGMHGIFDRPVAIAGK---------VEVRPMMYVALTYDHRLIDGREAV 438
Query 182 RFSKSIKNLLENPALMLVHL 201
F + IK+++E+P ++L+ +
Sbjct 439 TFLRKIKSVVEDPRVLLLDM 458
> pfa:PF13_0121 dihydrolipamide succinyltransferase component
of 2-oxoglutarate dehydrogenase complex (EC:2.3.1.61); K00658
2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide
succinyltransferase) [EC:2.3.1.61]
Length=421
Score = 90.1 bits (222), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 58/201 (28%), Positives = 106/201 (52%), Gaps = 15/201 (7%)
Query 1 LRHALNKELASQ-NIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSH-NVSV 58
LR LN + + ++ + + A +LA+ + P VN+ +N + ++ ++SV
Sbjct 232 LRSELNDIFQKKYSCKLGFVSLFMYASTLALKKMPNVNAYI----ENDEIVYKNYIDISV 287
Query 59 AIDSPGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISG 118
A+ +P GL VP ++N Q+ L +++ L L A++N+LS D +GGT +SN GV
Sbjct 288 AVATPNGLTVPVIRNCQNKNLPQLELALSDLATKARSNKLSIDDFSGGTFTISNGGVFGS 347
Query 119 TYIHPLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGA 178
P++ Q+ I+G+ ++ P V++E + R I+ + + DHR DG
Sbjct 348 MLSTPIINMPQSAILGMHTIKNRPVVVNNE---------IVIRPIMYLALTYDHRLLDGR 398
Query 179 TITRFSKSIKNLLENPALMLV 199
+F +I++ +ENP LML+
Sbjct 399 EAVQFLCAIRDYIENPNLMLI 419
> eco:b0115 aceF, ECK0114, JW0111; pyruvate dehydrogenase, dihydrolipoyltransacetylase
component E2 (EC:2.3.1.12); K00627
pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase)
[EC:2.3.1.12]
Length=630
Score = 89.4 bits (220), Expect = 8e-18, Method: Composition-based stats.
Identities = 58/195 (29%), Positives = 102/195 (52%), Gaps = 12/195 (6%)
Query 1 LRHALNKELASQ--NIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSV 58
R N+E A + +++I+ F++KA++ A+ + P NS + + Q T N+ V
Sbjct 440 FRKQQNEEAAKRKLDVKITPVVFIMKAVAAALEQMPRFNSSLSEDGQR-LTLKKYINIGV 498
Query 59 AIDSPGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISG 118
A+D+P GLVVP K+V ++E+ REL+ + A+ +L+ ++ GG +S++G +
Sbjct 499 AVDTPNGLVVPVFKDVNKKGIIELSRELMTISKKARDGKLTAGEMQGGCFTISSIGGLGT 558
Query 119 TYIHPLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGA 178
T+ P++ + I+GV + P + +GK+ R ++ S S DHR DGA
Sbjct 559 THFAPIVNAPEVAILGVSKSAMEPVW------NGKE---FVPRLMLPISLSFDHRVIDGA 609
Query 179 TITRFSKSIKNLLEN 193
RF I N L +
Sbjct 610 DGARFITIINNTLSD 624
> xla:447247 pdhx, MGC86218; pyruvate dehydrogenase complex, component
X; K13997 dihydrolipoamide dehydrogenase-binding protein
of pyruvate dehydrogenase complex
Length=478
Score = 88.6 bits (218), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 58/190 (30%), Positives = 97/190 (51%), Gaps = 7/190 (3%)
Query 5 LNKELASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAIDSPG 64
L KELA NI++S+ F+IKA + A+ + P VN +N E T S ++S+A+ +
Sbjct 290 LRKELAKDNIKVSVNDFIIKATAAALKQMPNVNVTWNGE---GATTLESIDISIAVATDR 346
Query 65 GLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYIHPL 124
GL+ P +K + EI L A+ +L P + GG+ ++SN+G+ T +
Sbjct 347 GLITPIIKQAASKGIQEIAATAKVLAQKARDGKLLPEEYQGGSFSISNLGMFGITGFSAV 406
Query 125 LFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATITRFS 184
+ Q+ I+ VGR + F + E+ N L + ++N + S+D R D T+F
Sbjct 407 INPPQSCILAVGRSRVELGFSEGEEG----NPQLCQKQVMNVTLSSDGRLVDDELATKFL 462
Query 185 KSIKNLLENP 194
+ + LENP
Sbjct 463 ECFRKNLENP 472
> xla:398314 dlat; dihydrolipoamide S-acetyltransferase (EC:2.3.1.12);
K00627 pyruvate dehydrogenase E2 component (dihydrolipoamide
acetyltransferase) [EC:2.3.1.12]
Length=628
Score = 88.2 bits (217), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 59/200 (29%), Positives = 100/200 (50%), Gaps = 12/200 (6%)
Query 1 LRHALNKELASQNIRISLTAFLIKAISLAINEYPIVNSKF-NTETQNSYTEFGSHNVSVA 59
LR LN+ + NI++S F+IKA +LA + P NS + +T + + +VSVA
Sbjct 440 LRKELNEVTKADNIKLSFNDFIIKASALACLKVPEANSSWMDTVIRQHHVV----DVSVA 495
Query 60 IDSPGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGT 119
+ +P GL+ P V N L I ++++ L A+ +L P + GGT +SN+G+
Sbjct 496 VSTPVGLITPIVFNAHIKGLASISKDVLSLATRAREGKLKPHEFQGGTFTVSNLGMYGIK 555
Query 120 YIHPLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGAT 179
++ QA I+ VG + R + +++ G + +++ + S DHR DGA
Sbjct 556 NFSAIINPPQACILAVGGSEN--RLIPADNEKG-----FDVASVMSVTLSCDHRVVDGAV 608
Query 180 ITRFSKSIKNLLENPALMLV 199
++ K LE P ML+
Sbjct 609 GAQWLAEFKKFLEKPTTMLL 628
> hsa:8050 PDHX, DLDBP, E3BP, OPDX, PDX1, proX; pyruvate dehydrogenase
complex, component X; K13997 dihydrolipoamide dehydrogenase-binding
protein of pyruvate dehydrogenase complex
Length=486
Score = 86.7 bits (213), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 55/190 (28%), Positives = 99/190 (52%), Gaps = 7/190 (3%)
Query 5 LNKELASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAIDSPG 64
+ ++L +I++S+ F+IKA ++ + + P VN ++ E ++SVA+ +
Sbjct 300 VRQDLVKDDIKVSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFI---DISVAVATDK 356
Query 65 GLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYIHPL 124
GL+ P +K+ + EI + L A+ +L P + GG+ ++SN+G+ +
Sbjct 357 GLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAV 416
Query 125 LFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATITRFS 184
+ QA I+ VGR + + + +ED +G N L+ R ++ + S+D R D TRF
Sbjct 417 INPPQACILAVGRFRPVLKL--TEDEEG--NAKLQQRQLITVTMSSDSRVVDDELATRFL 472
Query 185 KSIKNLLENP 194
KS K LENP
Sbjct 473 KSFKANLENP 482
> ath:AT1G54220 dihydrolipoamide S-acetyltransferase, putative
(EC:2.3.1.12); K00627 pyruvate dehydrogenase E2 component (dihydrolipoamide
acetyltransferase) [EC:2.3.1.12]
Length=539
Score = 84.3 bits (207), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 66/201 (32%), Positives = 96/201 (47%), Gaps = 12/201 (5%)
Query 1 LRHALNK-ELASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVA 59
LR LN + AS RIS+ ++KA +LA+ + P NS + T + +F + N++VA
Sbjct 349 LRSQLNSFKEASGGKRISVNDLVVKAAALALRKVPQCNSSW---TDDYIRQFKNVNINVA 405
Query 60 IDSPGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISG- 118
+ + GL VP VK+ L I E+ L AK N L P D GGT +SN+G G
Sbjct 406 VQTENGLYVPVVKDADRKGLSTIGEEVRLLAQKAKENSLKPEDYEGGTFTVSNLGGPFGI 465
Query 119 TYIHPLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGA 178
++ QA I+ VG ++ R V D + + S DHR DGA
Sbjct 466 KQFCAVVNPPQAAILAVGSAEK--RVVPGNGPD-----QFNFASYMPVTLSCDHRVVDGA 518
Query 179 TITRFSKSIKNLLENPALMLV 199
+ K+ K +ENP ML+
Sbjct 519 IGAEWLKAFKGYIENPKSMLL 539
> mmu:27402 Pdhx, AI481367, E3bp, Pdx1; pyruvate dehydrogenase
complex, component X; K13997 dihydrolipoamide dehydrogenase-binding
protein of pyruvate dehydrogenase complex
Length=501
Score = 84.3 bits (207), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 53/190 (27%), Positives = 99/190 (52%), Gaps = 7/190 (3%)
Query 5 LNKELASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAIDSPG 64
+ ++L +I++S+ F+I+A ++ + + P VN ++ E + S ++SVA+ +
Sbjct 315 VRRDLVKDDIKVSVNDFIIRAAAVTLKQMPGVNVTWDGEGPK---QLPSVDISVAVATDK 371
Query 65 GLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYIHPL 124
GL+ P +K+ + EI + L A+ +L P + GG+ ++SN+G+ +
Sbjct 372 GLITPIIKDAAAKGIQEIADSVKVLSKKARDGKLMPEEYQGGSFSISNLGMFGIDEFAAV 431
Query 125 LFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATITRFS 184
+ QA I+ VGR + P +ED +G N L+ ++ + S+D R D TRF
Sbjct 432 INPPQACILAVGRFR--PVLKLTEDEEG--NPQLQQHQLITVTMSSDSRVVDDELATRFL 487
Query 185 KSIKNLLENP 194
++ K LENP
Sbjct 488 ETFKANLENP 497
> cel:F23B12.5 hypothetical protein; K00627 pyruvate dehydrogenase
E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]
Length=507
Score = 84.0 bits (206), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 61/197 (30%), Positives = 94/197 (47%), Gaps = 14/197 (7%)
Query 5 LNKELASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSH-NVSVAIDSP 63
L K + Q +IS+ F+IKA +LA P NS + +S+ H +VSVA+ +P
Sbjct 323 LAKGTSGQATKISINDFIIKASALACQRVPEANSYW----MDSFIRENHHVDVSVAVSTP 378
Query 64 GGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVI-SGTYIH 122
GL+ P + N L I E+V L A+ +L P + GGT +SN+G+ S +
Sbjct 379 AGLITPIIFNAHAKGLATIASEIVELAQRAREGKLQPHEFQGGTFTVSNLGMFGSVSDFT 438
Query 123 PLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATITR 182
++ Q+ I+ +G + V E KK T++ + S DHR DGA
Sbjct 439 AIINPPQSCILAIGGASD--KLVPDEAEGYKKIKTMK------VTLSCDHRTVDGAVGAV 490
Query 183 FSKSIKNLLENPALMLV 199
+ + K LE P ML+
Sbjct 491 WLRHFKEFLEKPHTMLL 507
> tgo:TGME49_006610 biotin requiring domain-containing protein
/ 2-oxo acid dehydrogenases acyltransferase catalytic domain-containing
protein (EC:6.4.1.4 2.3.1.12 2.3.1.168); K00627
pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase)
[EC:2.3.1.12]
Length=932
Score = 84.0 bits (206), Expect = 3e-16, Method: Composition-based stats.
Identities = 54/194 (27%), Positives = 99/194 (51%), Gaps = 5/194 (2%)
Query 10 ASQNIRISLTAFLIKAISLAINEYPIVNSKFNTET--QNSYTEF-GSHNVSVAIDSPGGL 66
A Q ++++ L KA++L + ++PI+N+ +N + Q Y G+ NV++A+ GGL
Sbjct 740 APQQSTVTMSVLLAKAVALTLEKHPIMNAAYNPKDGGQIQYVPHPGAVNVAMAVSVDGGL 799
Query 67 VVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYIHPLLF 126
+ P ++NV ++ E+ + L A+ RL+ + + GT +SN+G+ + +L
Sbjct 800 LTPVLRNVNTKSVFELSADWAVLVDKARKRRLTAEENSAGTFYISNLGMFGVSQFDAVLP 859
Query 127 DGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATITRFSKS 186
G I+ VG + +P F + D R + + +ADHRH G+ F K
Sbjct 860 KGVGTIMAVGGTESVPFFPKTGTLDAPAGNP-SVRRRMTVTITADHRHIYGSHAAAFLKD 918
Query 187 IKNLLEN-PALMLV 199
+LLE P+ +L+
Sbjct 919 FASLLETRPSALLI 932
> ath:AT3G13930 dihydrolipoamide S-acetyltransferase, putative
(EC:2.3.1.12); K00627 pyruvate dehydrogenase E2 component (dihydrolipoamide
acetyltransferase) [EC:2.3.1.12]
Length=539
Score = 83.2 bits (204), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 67/205 (32%), Positives = 96/205 (46%), Gaps = 20/205 (9%)
Query 1 LRHALNK-ELASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVA 59
LR LN + AS RIS+ +IKA +LA+ + P NS + T +F + N++VA
Sbjct 349 LRSQLNSFQEASGGKRISVNDLVIKAAALALRKVPQCNSSW---TDEYIRQFKNVNINVA 405
Query 60 IDSPGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISG- 118
+ + GL VP VK+ L I E+ L AK N L P D GGT +SN+G G
Sbjct 406 VQTENGLYVPVVKDADKKGLSTIGEEVRFLAQKAKENSLKPEDYEGGTFTVSNLGGPFGI 465
Query 119 ----TYIHPLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRH 174
I+P QA I+ +G ++ R V D ++ + S DHR
Sbjct 466 KQFCAVINP----PQAAILAIGSAEK--RVVPGTGPD-----QYNVASYMSVTLSCDHRV 514
Query 175 CDGATITRFSKSIKNLLENPALMLV 199
DGA + K+ K +E P ML+
Sbjct 515 IDGAIGAEWLKAFKGYIETPESMLL 539
> mmu:235339 Dlat, 6332404G05Rik, DLTA, PDC-E2; dihydrolipoamide
S-acetyltransferase (E2 component of pyruvate dehydrogenase
complex) (EC:2.3.1.12); K00627 pyruvate dehydrogenase E2
component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]
Length=642
Score = 82.8 bits (203), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 58/200 (29%), Positives = 100/200 (50%), Gaps = 13/200 (6%)
Query 1 LRHALNKELASQNIRISLTAFLIKAISLAINEYPIVNSKF-NTETQNSYTEFGSHNVSVA 59
+R LNK L + +IS+ F+IKA +LA + P NS + +T + ++ +VSVA
Sbjct 455 VRKELNKMLEGKG-KISVNDFIIKASALACLKVPEANSSWMDTVIRQNHV----VDVSVA 509
Query 60 IDSPGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGT 119
+ +P GL+ P V N L I ++V L A+ +L P + GGT +SN+G+
Sbjct 510 VSTPAGLITPIVFNAHIKGLETIASDVVSLASKAREGKLQPHEFQGGTFTISNLGMFGIK 569
Query 120 YIHPLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGAT 179
++ QA I+ +G + + + +++ G + +++ + S DHR DGA
Sbjct 570 NFSAIINPPQACILAIGASED--KLIPADNEKG-----FDVASVMSVTLSCDHRVVDGAV 622
Query 180 ITRFSKSIKNLLENPALMLV 199
++ K LE P ML+
Sbjct 623 GAQWLAEFKKYLEKPITMLL 642
> ath:AT3G25860 LTA2; LTA2; dihydrolipoyllysine-residue acetyltransferase
Length=480
Score = 82.4 bits (202), Expect = 9e-16, Method: Compositional matrix adjust.
Identities = 59/182 (32%), Positives = 93/182 (51%), Gaps = 16/182 (8%)
Query 16 ISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAIDSPGGLVVPCVKNVQ 75
+++TA L KA +A+ ++P+VN+ SY S N++VA+ GGL+ P +++
Sbjct 307 VTMTALLAKAAGMALAQHPVVNASCKDGKSFSYNS--SINIAVAVAINGGLITPVLQDAD 364
Query 76 DLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYIHPLLFDGQAVIVGV 135
L L + ++ L G A++ +L P + GT LSN+G+ +L GQ I+ V
Sbjct 365 KLDLYLLSQKWKELVGKARSKQLQPHEYNSGTFTLSNLGMFGVDRFDAILPPGQGAIMAV 424
Query 136 GRVQQLPRFVDSEDSDG---KKNTTLEARDIVNCSFSADHRHCDGATITRFSKSIKNLLE 192
G + P V D DG KNT L VN +ADHR GA + F ++ ++E
Sbjct 425 GASK--PTVV--ADKDGFFSVKNTML-----VNV--TADHRIVYGADLAAFLQTFAKIIE 473
Query 193 NP 194
NP
Sbjct 474 NP 475
> tgo:TGME49_019550 dihydrolipoamide succinyltransferase component
of 2-oxoglutaratedehydrogenase complex, putative (EC:2.3.1.61);
K00658 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide
succinyltransferase) [EC:2.3.1.61]
Length=470
Score = 79.7 bits (195), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 56/203 (27%), Positives = 106/203 (52%), Gaps = 15/203 (7%)
Query 1 LRHALNKELASQN-IRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSH-NVSV 58
+R LN ++ +++ + + A ++A+ + P VN+ + + + SH ++SV
Sbjct 281 MRSELNPAFQERHGVKMGFVSAFMLASAMAMKKVPEVNAFI----EGNEIVYKSHVDISV 336
Query 59 AIDSPGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISG 118
A+ +P GL+VP V++ + + E+++EL L A+ N+++ D+ GGT +SN GV
Sbjct 337 AVATPTGLMVPVVRDCERKSWPELEKELAHLAVKARNNQIALEDMAGGTFTISNGGVYGS 396
Query 119 TYIHPLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGA 178
P+L Q+ I+G+ + + R V KN + R ++ + + DHR DG
Sbjct 397 MMGTPILNPPQSSILGMHGITK--RAV-------VKNDQVVIRPMMYLALTYDHRLIDGR 447
Query 179 TITRFSKSIKNLLENPALMLVHL 201
F I++ +E+P LML+ L
Sbjct 448 EAVTFLCHIRDYIEDPRLMLLDL 470
> hsa:1737 DLAT, DLTA, PDC-E2, PDCE2; dihydrolipoamide S-acetyltransferase
(EC:2.3.1.12); K00627 pyruvate dehydrogenase E2
component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]
Length=647
Score = 79.3 bits (194), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 57/200 (28%), Positives = 101/200 (50%), Gaps = 13/200 (6%)
Query 1 LRHALNKELASQNIRISLTAFLIKAISLAINEYPIVNSKF-NTETQNSYTEFGSHNVSVA 59
+R LNK L ++ +IS+ F+IKA +LA + P NS + +T + ++ +VSVA
Sbjct 460 VRKELNKILEGRS-KISVNDFIIKASALACLKVPEANSSWMDTVIRQNHV----VDVSVA 514
Query 60 IDSPGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGT 119
+ +P GL+ P V N + I ++V L A+ +L P + GGT +SN+G+
Sbjct 515 VSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIK 574
Query 120 YIHPLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGAT 179
++ QA I+ +G + + V +++ G + +++ + S DHR DGA
Sbjct 575 NFSAIINPPQACILAIGASED--KLVPADNEKG-----FDVASMMSVTLSCDHRVVDGAV 627
Query 180 ITRFSKSIKNLLENPALMLV 199
++ + LE P ML+
Sbjct 628 GAQWLAEFRKYLEKPITMLL 647
> cel:C30H6.7 hypothetical protein; K00627 pyruvate dehydrogenase
E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]
Length=337
Score = 77.4 bits (189), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 55/198 (27%), Positives = 93/198 (46%), Gaps = 14/198 (7%)
Query 4 ALNKELASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAIDSP 63
AL ++L +SL F+IKA +LA+ P VN ++ E GS ++SVA+ +P
Sbjct 139 ALRQKLKKSGTAVSLNDFIIKAAALALRSVPTVNVRWTPEG----IGLGSVDISVAVATP 194
Query 64 GGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVI-SGTYIH 122
GL+ P V+N L ++ I ++ L GLA+ ++L P GG+ +SN+G+ S T
Sbjct 195 TGLITPIVENSDILGVLAISSKVKELSGLARESKLKPQQFQGGSFTISNLGMFGSVTNFT 254
Query 123 PLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATITR 182
++ Q I+ +G + VD + LE + ++ + D R R
Sbjct 255 AIINPPQCAILTIGGTRSEVVSVDGQ---------LETQKLMGVNLCFDGRAISEECAKR 305
Query 183 FSKSIKNLLENPALMLVH 200
F L +P L++
Sbjct 306 FLLHFSESLSDPELLIAE 323
> tpv:TP01_0262 dihydrolipoamide succinyltransferase; K00658 2-oxoglutarate
dehydrogenase E2 component (dihydrolipoamide succinyltransferase)
[EC:2.3.1.61]
Length=456
Score = 77.0 bits (188), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 55/202 (27%), Positives = 101/202 (50%), Gaps = 17/202 (8%)
Query 1 LRHALNKELASQNIRISLTAFLIKAISLAINEYPIVNSKF--NTETQNSYTEFGSHNVSV 58
+R LN E + ++ + ++A +LA+ + PI+NS N +Y + +SV
Sbjct 270 VRKMLN-ESGEVSCKLGFVSAFMRASTLALLKMPIMNSYIEGNEMVTKNYVD-----ISV 323
Query 59 AIDSPGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISG 118
A+ +P GL+VP ++N + E++ L+ + A+ ++ D+TGGT +SN GV
Sbjct 324 AVATPTGLLVPVIRNCEFKNWEELELSLLEMAKKAREGSITIEDMTGGTFTISNGGVYGS 383
Query 119 TYIHPLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGA 178
P++ Q+ I+G+ + + P D + R ++N + + DHR DG
Sbjct 384 LLSTPIINPPQSSILGMHAITKRPVVRDDN---------IVIRPVMNVALTYDHRLIDGR 434
Query 179 TITRFSKSIKNLLENPALMLVH 200
F +IK +ENP+L+L+
Sbjct 435 DAVTFLNTIKKFIENPSLLLLK 456
> dre:393532 pdhx, MGC66110, zgc:66110, zgc:85977; pyruvate dehydrogenase
complex, component X; K13997 dihydrolipoamide dehydrogenase-binding
protein of pyruvate dehydrogenase complex
Length=490
Score = 75.9 bits (185), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 52/193 (26%), Positives = 98/193 (50%), Gaps = 11/193 (5%)
Query 5 LNKELASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAIDSPG 64
+ K LA +NI++S+ F+IKA ++++ E P VN ++ + G ++S+A+ +
Sbjct 305 VRKRLAEENIKVSVNDFIIKAAAVSLRELPAVNVSWSADGPQP---LGFIHISMAVATDR 361
Query 65 GLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYIHPL 124
GL+ P +++ D L EI L A+ +L P + GG+ ++SN+G+ + +
Sbjct 362 GLITPIIRDAADKGLQEISSTAKALAQKARDGKLLPEEYQGGSFSVSNLGMFGISEFSAV 421
Query 125 LFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATITRFS 184
+ QA I+ VG + + +ED TL+ + + + S+D R D +RF
Sbjct 422 INPPQACILAVGG-SRTELSLSAED-------TLQTQHTLTVTLSSDARLVDDELASRFL 473
Query 185 KSIKNLLENPALM 197
++ + LE P M
Sbjct 474 ETFRLNLERPERM 486
> ath:AT1G34430 EMB3003 (embryo defective 3003); acyltransferase/
dihydrolipoyllysine-residue acetyltransferase/ protein binding;
K00627 pyruvate dehydrogenase E2 component (dihydrolipoamide
acetyltransferase) [EC:2.3.1.12]
Length=465
Score = 72.0 bits (175), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 49/163 (30%), Positives = 83/163 (50%), Gaps = 12/163 (7%)
Query 33 YPIVNSKFNTETQNSYTEFGSHNVSVAIDSPGGLVVPCVKNVQDLTLVEIQRELVRLQGL 92
+P+VNS + NS+ S NV+VA+ GGL+ P ++N + + + R+ L
Sbjct 309 HPVVNS--SCRDGNSFVYNSSINVAVAVAIDGGLITPVLQNADKVDIYSLSRKWKELVDK 366
Query 93 AKANRLSPADLTGGTIALSNVGVISGTYIHPLLFDGQAVIVGVGRVQQLPRFVDSEDSD- 151
A+A +L P + GT LSN+G+ +L G I+ VG Q P V ++D
Sbjct 367 ARAKQLQPQEYNTGTFTLSNLGMFGVDRFDAILPPGTGAIMAVGASQ--PSVVATKDGRI 424
Query 152 GKKNTTLEARDIVNCSFSADHRHCDGATITRFSKSIKNLLENP 194
G KN + + +ADHR GA + +F +++ +++E+P
Sbjct 425 GMKNQ-------MQVNVTADHRVIYGADLAQFLQTLASIIEDP 460
> ath:AT5G55070 2-oxoacid dehydrogenase family protein (EC:2.3.1.61);
K00658 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide
succinyltransferase) [EC:2.3.1.61]
Length=464
Score = 70.9 bits (172), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 46/193 (23%), Positives = 95/193 (49%), Gaps = 12/193 (6%)
Query 9 LASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAIDSPGGLVV 68
L +++ L + IKA A+ P+VN+ + + Y ++ ++S+A+ + GLVV
Sbjct 284 LEKHGVKLGLMSGFIKAAVSALQHQPVVNAVIDGD-DIIYRDY--VDISIAVGTSKGLVV 340
Query 69 PCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYIHPLLFDG 128
P +++ + +I++ + L A +S ++ GG+ +SN GV P++
Sbjct 341 PVIRDADKMNFADIEKTINGLAKKATEGTISIDEMAGGSFTVSNGGVYGSLISTPIINPP 400
Query 129 QAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATITRFSKSIK 188
Q+ I+G+ + Q P V ++ R ++ + + DHR DG F + IK
Sbjct 401 QSAILGMHSIVQRPMVV---------GGSVVPRPMMYVALTYDHRLIDGREAVYFLRRIK 451
Query 189 NLLENPALMLVHL 201
+++E+P +L+ +
Sbjct 452 DVVEDPQRLLLDI 464
> ath:AT3G52200 LTA3; LTA3; ATP binding / dihydrolipoyllysine-residue
acetyltransferase; K00627 pyruvate dehydrogenase E2
component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]
Length=637
Score = 68.9 bits (167), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 50/191 (26%), Positives = 96/191 (50%), Gaps = 6/191 (3%)
Query 4 ALNKEL-ASQNIRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAIDS 62
A KEL + +++S+ +IKA+++A+ N+ ++ E + S ++S+A+ +
Sbjct 446 AFRKELQENHGVKVSVNDIVIKAVAVALRNVRQANAFWDAE-KGDIVMCDSVDISIAVAT 504
Query 63 PGGLVVPCVKNVQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYIH 122
GL+ P +KN ++ I E+ L A++ +L+P + GGT ++SN+G+
Sbjct 505 EKGLMTPIIKNADQKSISAISLEVKELAQKARSGKLAPHEFQGGTFSISNLGMYPVDNFC 564
Query 123 PLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATITR 182
++ QA I+ VGR ++ V D K + + +N + SADHR DG
Sbjct 565 AIINPPQAGILAVGRGNKVVEPVIGLDGIEKPSVVTK----MNVTLSADHRIFDGQVGAS 620
Query 183 FSKSIKNLLEN 193
F +++ E+
Sbjct 621 FMSELRSNFED 631
> ath:AT4G26910 2-oxoacid dehydrogenase family protein (EC:2.3.1.61);
K00658 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide
succinyltransferase) [EC:2.3.1.61]
Length=464
Score = 67.4 bits (163), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 44/188 (23%), Positives = 92/188 (48%), Gaps = 12/188 (6%)
Query 14 IRISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAIDSPGGLVVPCVKN 73
+++ L + IKA A+ P+VN+ + + Y ++ ++S+A+ + GLVVP ++
Sbjct 289 VKLGLMSGFIKAAVSALQHQPVVNAVIDGD-DIIYRDY--VDISIAVGTSKGLVVPVIRG 345
Query 74 VQDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYIHPLLFDGQAVIV 133
+ EI++ + L A +S ++ GG+ +SN GV P++ Q+ I+
Sbjct 346 ADKMNFAEIEKTINSLAKKANEGTISIDEMAGGSFTVSNGGVYGSLISTPIINPPQSAIL 405
Query 134 GVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATITRFSKSIKNLLEN 193
G+ + P V ++ R ++ + + DHR DG F + +K+++E+
Sbjct 406 GMHSIVSRPMVV---------GGSVVPRPMMYVALTYDHRLIDGREAVYFLRRVKDVVED 456
Query 194 PALMLVHL 201
P +L+ +
Sbjct 457 PQRLLLDI 464
> pfa:PF10_0407 dihydrolipoamide acyltransferase, putative (EC:2.3.1.12);
K00627 pyruvate dehydrogenase E2 component (dihydrolipoamide
acetyltransferase) [EC:2.3.1.12]
Length=640
Score = 45.1 bits (105), Expect = 2e-04, Method: Composition-based stats.
Identities = 37/178 (20%), Positives = 72/178 (40%), Gaps = 10/178 (5%)
Query 15 RISLTAFLIKAISLAINEYPIVNSKFNTETQNSYTEFGSHNVSVAIDSPGGLVVPCVKNV 74
+IS++ + K +S + +P++ S + + N+ A+ P L+ P +K V
Sbjct 465 KISMSVIINKCVSSVLLNHPLIYSTYIDKDNGKILYNKDVNIGNALGLPDSLLTPVLKKV 524
Query 75 QDLTLVEIQRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYIHPLLFDGQAVIVG 134
+ + E L K LS D+TG +SN+G+ + +L + I+
Sbjct 525 DKKDIYTLANEWKILVEKGKNGLLSSNDMTGSNFYISNLGMFNTYQFDAILPKNSSCILS 584
Query 135 VGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATITRFSKSIKNLLE 192
+G + + ED +K + + + DHRH G+ F + +E
Sbjct 585 IG--TNIGSIDNLEDLKIQKGMMM--------TLTCDHRHIYGSHAAAFMNDLSKFIE 632
> ath:AT5G44950 F-box family protein
Length=438
Score = 31.6 bits (70), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 31/106 (29%), Positives = 46/106 (43%), Gaps = 19/106 (17%)
Query 52 GSHNVSVAIDSPGGLVVP---------CVKNVQDLTLVEIQRELVRLQGLAKANRLSPAD 102
GS++ SV ID+PG + VKN+ L +++ E GL L P D
Sbjct 215 GSNDFSVEIDAPGLKYMSFRDSQSDRIVVKNLSSLVKIDLDTEFNLKFGLGSP--LEPED 272
Query 103 LTGGTIA---LSNVGVISGTYI-HPLLFDGQAVIVGVGRVQQLPRF 144
LT I L+ + + I HP L V+ ++ QLP+F
Sbjct 273 LTKRDIIRDFLTGISSVKHMIISHPTL----EVLYRYSKIGQLPKF 314
> tgo:TGME49_106660 RNA pseudouridine synthase domain containing
protein (EC:3.4.21.72 3.2.1.3 3.2.1.17)
Length=6535
Score = 31.2 bits (69), Expect = 2.2, Method: Composition-based stats.
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query 122 HPLLFDGQAVIVGVGRVQQLPRFVDSEDSDGKKNTTLEARDIVNCSFSADHRHCDGATIT 181
HPLL G A +G G Q +FV S+ S G + L A ++ + S ++ +
Sbjct 5762 HPLLASGLASRLGQGLTPQERQFVLSQQSGGSTSFLLPALPSLSENLSGHD-----SSGS 5816
Query 182 RFSKSIKNLLENPA 195
RF S +NLL P
Sbjct 5817 RFDASQRNLLRLPG 5830
> ath:AT1G79950 helicase-related; K11136 regulator of telomere
elongation helicase 1
Length=1040
Score = 31.2 bits (69), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 0/84 (0%)
Query 83 QRELVRLQGLAKANRLSPADLTGGTIALSNVGVISGTYIHPLLFDGQAVIVGVGRVQQLP 142
Q EL RL+ ANR SP + G + + + ++ T P + G + R +L
Sbjct 817 QNELSRLEAFPPANRASPLERDGNNVKRNGLTILKHTGKIPRIVKGDVMQGCSSRKAKLV 876
Query 143 RFVDSEDSDGKKNTTLEARDIVNC 166
D E++ ++ + + NC
Sbjct 877 ELSDDEETPVERRCEVVDLESDNC 900
> sce:YGR227W DIE2, ALG10; Die2p (EC:2.4.1.-); K03850 alpha-1,2-glucosyltransferase
[EC:2.4.1.-]
Length=525
Score = 30.8 bits (68), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 4/46 (8%)
Query 28 LAINEYPIVNSKFNTETQNSYTEFGSHNVSVAIDSPGGLVVPCVKN 73
LA+ I+ +FNT T N+Y + H AID LV+P +KN
Sbjct 226 LAVERPAILQKQFNTHTFNNYLKLFIH----AIDDFSNLVLPYMKN 267
Lambda K H
0.319 0.134 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 6124680020
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
Posted date: Sep 17, 2011 2:57 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40