bitscore colors: <40, 40-50 , 50-80, 80-200, >200

           BLASTP 2.2.24+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: kyva
           112,920 sequences; 47,500,486 total letters



Query=  Eten_0633_orf1
Length=335
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

  CE00858                                                              107    2e-23
  Hs4503667                                                            102    1e-21
  Hs15029514                                                           101    2e-21
  Hs20549163                                                           100    3e-21
  Hs4557591                                                            100    3e-21
  Hs5453766                                                           95.5    1e-19
  Hs4503665                                                           94.4    3e-19
  Hs18497288                                                          92.8    1e-18
  Hs17978491                                                          92.4    1e-18
  Hs4503565                                                           92.0    2e-18
  Hs4505037                                                           91.7    2e-18
  Hs4557731                                                           91.7    2e-18
  Hs7305025                                                           91.7    2e-18
  Hs4503663                                                           85.9    1e-16
  Hs8393299                                                           85.1    2e-16
  7304328                                                             85.1    2e-16
  7295695                                                             84.3    3e-16
  CE25695_1                                                           83.6    6e-16
  CE26701                                                             82.0    2e-15
  CE26702                                                             81.6    2e-15
  Hs9665262                                                           81.3    3e-15
  Hs9665253                                                           80.9    4e-15
  Hs20536571                                                          80.5    4e-15
  Hs5922009                                                           80.5    5e-15
  CE28049                                                             79.7    8e-15
  Hs4557733                                                           79.3    9e-15
  Hs5922007                                                           79.0    1e-14
  Hs5922011                                                           78.6    2e-14
  CE16142                                                             78.6    2e-14
  Hs13518039                                                          77.0    5e-14
  Hs13518037                                                          77.0    5e-14
  Hs19743803                                                          75.5    1e-13
  Hs10190748                                                          75.1    2e-13
  Hs22044235                                                          75.1    2e-13
  Hs4505395                                                           74.7    3e-13
  Hs5453764                                                           70.9    4e-12
  Hs13124888                                                          68.2    2e-11
  7295215                                                             68.2    2e-11
  CE24549                                                             68.2    2e-11
  Hs20556510                                                          63.2    7e-10
  7290390                                                             62.4    1e-09
  Hs4557799                                                           62.4    1e-09
  Hs13249344                                                          61.2    3e-09
  7294668                                                             61.2    3e-09
  Hs6679056                                                           60.8    4e-09
  CE05481                                                             60.8    4e-09
  Hs20543258                                                          60.5    5e-09
  Hs4885229                                                           60.5    5e-09
  7291068_3                                                           59.3    1e-08
  Hs4507833                                                           58.5    2e-08


> CE00858
Length=1106

 Score =  107 bits (268),  Expect = 2e-23, Method: Compositional matrix adjust.
 Identities = 85/209 (40%), Positives = 107/209 (51%), Gaps = 21/209 (10%)

Query  25   CSRVEHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPG  84
            C+R +    C +G    C C +GFT  G      C D+DEC      C+     C N  G
Sbjct  373  CARCDQNAKCSNG---VCTCSEGFTGDGFR----CYDVDECEIPGAVCRDHS-ICSNTIG  424

Query  85   SFTCGC-GPYRQEKDGVCIDINECSTNR---GNCDENSDCINLDGEEQLCKCHKGWTGNN  140
            SF C C G YR E DG C D++EC       G+ ++ + CIN DG  + C C  G+ G+ 
Sbjct  425  SFECTCHGGYRFE-DGKCEDVDECRELPKICGDPNKGTKCINKDGTFE-CLCKDGYEGD-  481

Query  141  DKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGK  200
              P+  CRD+NEC +NP  C  NS CTN  G Y+CEC AGFE  + G+ C   D C    
Sbjct  482  --PSSECRDVNEC-KNPDACGPNSQCTNTQGGYECECLAGFERIAEGAHCTDRDECAV--  536

Query  201  NDCDTVFAACSLVPGSFKCECIQGFRGAG  229
              C    A CS   GS+KCEC  GF G G
Sbjct  537  EPCHPA-AICSNTRGSYKCECRDGFVGDG  564


 Score = 43.1 bits (100),  Expect = 8e-04, Method: Compositional matrix adjust.
 Identities = 18/37 (48%), Positives = 24/37 (64%), Gaps = 0/37 (0%)

Query  61   DIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEK  97
            D+DEC  G+DNC  +  DC+N PGSF C C  Y + +
Sbjct  240  DMDECEMGIDNCPNEQPDCLNTPGSFLCLCFEYDEAQ  276


 Score = 39.3 bits (90),  Expect = 0.013, Method: Compositional matrix adjust.
 Identities = 35/119 (29%), Positives = 51/119 (42%), Gaps = 10/119 (8%)

Query  113  NCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVAC-RDINECNENPSICPSNSVCTNLAG  171
            +CD +  C  + G      C  GW G+      +C +DI+EC  +   C   S C N  G
Sbjct  804  HCDGSVACDVITGMCPGALCRAGWEGS------SCDQDIDECEMSLVTCAVGSQCVNTRG  857

Query  172  SYKCECSAGFEPDSSGSGCVTEDFCGTGKN-DCDTVFAACSLVPGSFKCECIQGFRGAG  229
             Y+C+C  GF P   G  C   D C +  +  C         +  + KC C +G+ G G
Sbjct  858  GYRCDCKGGFAP--VGKECKPIDRCLSRFSVPCSRNAECVESIESNPKCVCRKGYHGDG  914


 Score = 35.4 bits (80),  Expect = 0.17, Method: Compositional matrix adjust.
 Identities = 26/80 (32%), Positives = 33/80 (41%), Gaps = 2/80 (2%)

Query  61   DIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDGVCIDINEC-STNRGNCDENSD  119
            DIDEC   L  C   G  CVN  G + C C          C  I+ C S     C  N++
Sbjct  835  DIDECEMSLVTCAV-GSQCVNTRGGYRCDCKGGFAPVGKECKPIDRCLSRFSVPCSRNAE  893

Query  120  CINLDGEEQLCKCHKGWTGN  139
            C+        C C KG+ G+
Sbjct  894  CVESIESNPKCVCRKGYHGD  913


> Hs4503667
Length=2911

 Score =  102 bits (253),  Expect = 1e-21, Method: Compositional matrix adjust.
 Identities = 70/187 (37%), Positives = 97/187 (51%), Gaps = 12/187 (6%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDG  99
             F C CQ G++ +    ++ C D+DEC  G  NC      C+NIPGSF C C         
Sbjct  1347  FICHCQLGYSVK--KGTTGCTDVDECEIGAHNCDMHA-SCLNIPGSFKCSCREGWIGNGI  1403

Query  100   VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSI  159
              CID++ECS     C  N+ C+N  G  + C C +G+TG+       C D++EC EN ++
Sbjct  1404  KCIDLDECSNGTHQCSINAQCVNTPGSYR-CACSEGFTGDG----FTCSDVDECAENINL  1458

Query  160   CPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKC  219
             C  N  C N+ G+Y+CEC  GF P S    C   D C + +N C  V   C+ +PG F C
Sbjct  1459  C-ENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDEC-SFQNIC--VSGTCNNLPGMFHC  1514

Query  220   ECIQGFR  226
              C  G+ 
Sbjct  1515  ICDDGYE  1521


 Score = 99.4 bits (246),  Expect = 1e-20, Method: Compositional matrix adjust.
 Identities = 71/200 (35%), Positives = 100/200 (50%), Gaps = 15/200 (7%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDG  99
             + C C  GF    +++  TCID++EC    + C    G+C N  GSF C C      K G
Sbjct  1305  YRCLCYDGFMAS-MDMK-TCIDVNECDLNSNICMF--GECENTKGSFICHCQLGYSVKKG  1360

Query  100   V--CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP  157
                C D++EC     NCD ++ C+N+ G  + C C +GW GN     + C D++EC+   
Sbjct  1361  TTGCTDVDECEIGAHNCDMHASCLNIPGSFK-CSCREGWIGNG----IKCIDLDECSNGT  1415

Query  158   SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSF  217
               C  N+ C N  GSY+C CS GF  D  G  C   D C    N C+     C  VPG++
Sbjct  1416  HQCSINAQCVNTPGSYRCACSEGFTGD--GFTCSDVDECAENINLCEN--GQCLNVPGAY  1471

Query  218   KCECIQGFRGAGTVNTCEPL  237
             +CEC  GF  A    +C+ +
Sbjct  1472  RCECEMGFTPASDSRSCQDI  1491


 Score = 90.9 bits (224),  Expect = 3e-18, Method: Compositional matrix adjust.
 Identities = 71/201 (35%), Positives = 98/201 (48%), Gaps = 21/201 (10%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC------GPY  93
             F C C +G+   G  +   C+DID C +    C+  GG CVN  GSF C C       P 
Sbjct  1137  FECECFEGYE-SGFMMMKNCMDIDGCERNPLLCR--GGTCVNTEGSFQCDCPLGHELSPS  1193

Query  94    RQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINEC  153
             R++    C+DINECS +   C  N  C+N+ G  Q C C+ G+    D+    C DI+EC
Sbjct  1194  RED----CVDINECSLSDNLC-RNGKCVNMIGTYQ-CSCNPGYQATPDRQ--GCTDIDEC  1245

Query  154   NENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLV  213
                   C  ++ CTN  GSY+C CS G+     G  C   D C    + CD     C+ +
Sbjct  1246  MIMNGGC--DTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDG--GQCTNI  1301

Query  214   PGSFKCECIQGFRGAGTVNTC  234
             PG ++C C  GF  +  + TC
Sbjct  1302  PGEYRCLCYDGFMASMDMKTC  1322


 Score = 89.0 bits (219),  Expect = 1e-17, Method: Compositional matrix adjust.
 Identities = 69/197 (35%), Positives = 98/197 (49%), Gaps = 14/197 (7%)

Query  30    HAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCG  89
             HA        F C+C++G+   GI     CID+DEC+ G   C      CVN PGS+ C 
Sbjct  1380  HASCLNIPGSFKCSCREGWIGNGIK----CIDLDECSNGTHQCSINA-QCVNTPGSYRCA  1434

Query  90    CGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRD  149
             C          C D++EC+ N   C EN  C+N+ G  + C+C  G+T  +D  + +C+D
Sbjct  1435  CSEGFTGDGFTCSDVDECAENINLC-ENGQCLNVPGAYR-CECEMGFTPASD--SRSCQD  1490

Query  150   INECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAA  209
             I+EC+   +IC S + C NL G + C C  G+E D +G  C   D C    N    V   
Sbjct  1491  IDECSFQ-NICVSGT-CNNLPGMFHCICDDGYELDRTGGNCTDIDECADPIN---CVNGL  1545

Query  210   CSLVPGSFKCECIQGFR  226
             C   PG ++C C   F+
Sbjct  1546  CVNTPGRYECNCPPDFQ  1562


 Score = 87.4 bits (215),  Expect = 4e-17, Method: Compositional matrix adjust.
 Identities = 73/214 (34%), Positives = 100/214 (46%), Gaps = 31/214 (14%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
             F C C  GF+   + L   C DIDEC+ G DN  Q+  DC+N PGS+ C C   ++   +
Sbjct  1830  FRCECPTGFSYNDLLL--VCEDIDECSNG-DNLCQRNADCINSPGSYRCECAAGFKLSPN  1886

Query  99    GVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPS  158
             G C+D NEC      C     C++L G  Q C CH G+  + D+    C D++EC  +P 
Sbjct  1887  GACVDRNECLEIPNVCSHGL-CVDLQGSYQ-CICHNGFKASQDQ--TMCMDVDECERHPC  1942

Query  159   ICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAA------CSL  212
                 N  C N  GSY C C  GFE  +  + C+  D       +C + F        C  
Sbjct  1943  ---GNGTCKNTVGSYNCLCYPGFEL-THNNDCLDID-------ECSSFFGQVCRNGRCFN  1991

Query  213   VPGSFKCECIQGF------RGAGTVNTCEPLPGN  240
               GSFKC C +G+      +     N C  LPG+
Sbjct  1992  EIGSFKCLCNEGYELTPDGKNCIDTNECVALPGS  2025


 Score = 86.7 bits (213),  Expect = 7e-17, Method: Compositional matrix adjust.
 Identities = 69/189 (36%), Positives = 93/189 (49%), Gaps = 20/189 (10%)

Query  40    FWCACQKGFTPQGINLSST-CIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQE  96
             F C C+ G+T    ++S T CID+DEC+Q    C      C N  GS+ C C  G   QE
Sbjct  2471  FRCFCKVGYT---TDISGTSCIDLDECSQSPKPCNYI---CKNTEGSYQCSCPRGYVLQE  2524

Query  97    KDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNEN  156
                 C D++EC T + NC     C+N  G    CKC  G+T    + + AC D NEC   
Sbjct  2525  DGKTCKDLDECQTKQHNCQ--FLCVNTLGG-FTCKCPPGFT----QHHTACIDNNECGSQ  2577

Query  157   PSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGS  216
             P +C    +C N  GS+ CEC  GF  D++G  C   D C  G + C      C  + G 
Sbjct  2578  PLLCGGKGICQNTPGSFSCECQRGFSLDATGLNCEDVDEC-DGNHRCQ---HGCQNILGG  2633

Query  217   FKCECIQGF  225
             ++C C QG+
Sbjct  2634  YRCGCPQGY  2642


 Score = 82.0 bits (201),  Expect = 2e-15, Method: Compositional matrix adjust.
 Identities = 67/165 (40%), Positives = 87/165 (52%), Gaps = 16/165 (9%)

Query  67   QGLDNCKQKGGDCVN---IP--GSFTCGCGP-YRQEKDGVCIDINECSTNRGNCDENSDC  120
            Q +D CK     C+N   IP   S+ C C   Y+Q+ +G CID++EC++N      N DC
Sbjct  492  QTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCT---NGDC  548

Query  121  INLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAG  180
            +N  G    CKCH G+     K   AC DI+EC +N  +C  N  C N  GS++C C+AG
Sbjct  549  VNTPGS-YYCKCHAGFQRTPTKQ--ACIDIDECIQNGVLC-KNGRCVNSDGSFQCICNAG  604

Query  181  FEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGF  225
            FE  + G  CV  D C T  N C  +   C    GSFKC C  GF
Sbjct  605  FELTTDGKNCVDHDEC-TTTNMC--LNGMCINEDGSFKCICKPGF  646


 Score = 76.6 bits (187),  Expect = 6e-14, Method: Compositional matrix adjust.
 Identities = 74/225 (32%), Positives = 95/225 (42%), Gaps = 37/225 (16%)

Query  40   FWCACQKGFT--PQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQE  96
            F C C+ GF   P G      C D+DEC Q    C    G C+N  GSF C C P     
Sbjct  638  FKCICKPGFVLAPNG----RYCTDVDEC-QTPGICMN--GHCINSEGSFRCDCPPGLAVG  690

Query  97   KDG-VCIDINECSTNRGNCDENSDCINLDGEEQLCKC-----------------------  132
             DG VC+D +  ST  G   +        G     +C                       
Sbjct  691  MDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAE  750

Query  133  HKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVT  192
              G   +     V  RDINEC  +P IC +N +C NL GSY+C C++G+EPD+SG  C+ 
Sbjct  751  FHGLCSSGVGITVDGRDINECALDPDIC-ANGICENLRGSYRCNCNSGYEPDASGRNCID  809

Query  193  EDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCEPL  237
             D C   +  CD     C   PGS+ C C  G+       TCE +
Sbjct  810  IDECLVNRLLCDN--GLCRNTPGSYSCTCPPGYVFRTETETCEDI  852


 Score = 75.1 bits (183),  Expect = 2e-13, Method: Compositional matrix adjust.
 Identities = 69/211 (32%), Positives = 98/211 (46%), Gaps = 27/211 (12%)

Query  40    FWCACQKGFTPQGINLS-STCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKD  98
             F C C  GF    +++    C DIDEC    D C    G CVN PGSF C C  +   + 
Sbjct  1095  FKCRCNSGFA---LDMEERNCTDIDECRISPDLCGS--GICVNTPGSFECEC--FEGYES  1147

Query  99    GV-----CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINEC  153
             G      C+DI+ C  N   C     C+N +G  Q C C  G   +  + +  C DINEC
Sbjct  1148  GFMMMKNCMDIDGCERNPLLC-RGGTCVNTEGSFQ-CDCPLGHELSPSRED--CVDINEC  1203

Query  154   NENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLV  213
             + + ++C  N  C N+ G+Y+C C+ G++      GC   D C      CDT    C+  
Sbjct  1204  SLSDNLC-RNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDT---QCTNS  1259

Query  214   PGSFKCECIQGF------RGAGTVNTCEPLP  238
              GS++C C +G+      R    ++ CE  P
Sbjct  1260  EGSYECSCSEGYALMPDGRSCADIDECENNP  1290


 Score = 75.1 bits (183),  Expect = 2e-13, Method: Compositional matrix adjust.
 Identities = 68/194 (35%), Positives = 91/194 (46%), Gaps = 18/194 (9%)

Query  54    NLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKDGV-CIDINECSTNR  111
             +L  T  D++EC +    C    G C+N  GSF C C   Y  +  GV C+D +ECS   
Sbjct  2163  SLHDTREDVNECLESPGICSN--GQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSI--  2218

Query  112   GNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAG  171
             GN   N  C N+ G  + C C++G+      P + C DINEC +NP +C     C N  G
Sbjct  2219  GNPCGNGTCTNVIGSFE-CNCNEGF---EPGPMMNCEDINECAQNPLLCALR--CMNTFG  2272

Query  172   SYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFR----G  227
             SY+C C  G+        C   D C  G +DC++    C  + G+F C C  G      G
Sbjct  2273  SYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDG  2332

Query  228   AGTV--NTCEPLPG  239
              G V  N C   PG
Sbjct  2333  EGCVDENECRTKPG  2346


 Score = 73.2 bits (178),  Expect = 8e-13, Method: Compositional matrix adjust.
 Identities = 71/205 (34%), Positives = 92/205 (44%), Gaps = 24/205 (11%)

Query  29   EHAESCQSG------DGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNI  82
             HA  C +G        + C C  G+     + +  CID+DEC           GDCVN 
Sbjct  499  HHANLCLNGRCIPTVSSYRCECNMGYKQ---DANGDCIDVDECTSN----PCTNGDCVNT  551

Query  83   PGSFTCGC--GPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNN  140
            PGS+ C C  G  R      CIDI+EC  N   C +N  C+N DG  Q C C+ G+    
Sbjct  552  PGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLC-KNGRCVNSDGSFQ-CICNAGFELTT  609

Query  141  DKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGK  200
            D  N  C D +EC    ++C  N +C N  GS+KC C  GF    +G  C   D C T  
Sbjct  610  DGKN--CVDHDECTTT-NMC-LNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPG  665

Query  201  NDCDTVFAACSLVPGSFKCECIQGF  225
                 +   C    GSF+C+C  G 
Sbjct  666  ---ICMNGHCINSEGSFRCDCPPGL  687


 Score = 71.6 bits (174),  Expect = 2e-12, Method: Compositional matrix adjust.
 Identities = 68/229 (29%), Positives = 91/229 (39%), Gaps = 51/229 (22%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDG  99
             + C+C +G+  Q      TC D+DEC     NC+     CVN  G FTC C P   +   
Sbjct  2512  YQCSCPRGYVLQ--EDGKTCKDLDECQTKQHNCQFL---CVNTLGGFTCKCPPGFTQHHT  2566

Query  100   VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECN-----  154
              CID NEC +    C     C N  G    C+C +G++   D   + C D++EC+     
Sbjct  2567  ACIDNNECGSQPLLCGGKGICQNTPGSFS-CECQRGFS--LDATGLNCEDVDECDGNHRC  2623

Query  155   ----------------------------------ENPSICPSNSVCTNLAGSYKCECSAG  180
                                                NP+ C S S C N  GSYKC C +G
Sbjct  2624  QHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSAS-CYNTLGSYKCACPSG  2682

Query  181   FEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAG  229
             F  D   S C   + C + KN C+     CS   G + C C  G+   G
Sbjct  2683  FSFDQFSSACHDVNECSSSKNPCN---YGCSNTEGGYLCGCPPGYYRVG  2728


 Score = 70.1 bits (170),  Expect = 7e-12, Method: Compositional matrix adjust.
 Identities = 74/214 (34%), Positives = 102/214 (47%), Gaps = 27/214 (12%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
             + C C  GF    +  ++ C+DIDEC+        + G C N  GSF C C   Y    D
Sbjct  1954  YNCLCYPGFE---LTHNNDCLDIDECSSFFGQ-VCRNGRCFNEIGSFKCLCNEGYELTPD  2009

Query  99    GV-CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP  157
             G  CID NEC    G+C   + C NL+G  + C C  G+   ++     C DINEC+E+P
Sbjct  2010  GKNCIDTNECVALPGSCSPGT-CQNLEGSFR-CICPPGYEVKSEN----CIDINECDEDP  2063

Query  158   SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCV--TEDFCGTGKNDCDTVFAACSLVPG  215
             +IC   S CTN  G ++C C  GF    +G  C    + FC T   +       CS VP 
Sbjct  2064  NICLFGS-CTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFEN-----GKCS-VPK  2116

Query  216   SF-----KCECIQGFRGAGTVNTCEPLPGNEDLA  244
             +F     KC C     G G  + CE  P ++++A
Sbjct  2117  AFNTTKAKC-CCSKMPGEGWGDPCELCPKDDEVA  2149


 Score = 69.7 bits (169),  Expect = 8e-12, Method: Compositional matrix adjust.
 Identities = 64/192 (33%), Positives = 86/192 (44%), Gaps = 14/192 (7%)

Query  46    KGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKDGV-CID  103
             K   P G   ++   DIDEC    + C    G C+N  GSF C C   Y  +  G  CID
Sbjct  2433  KKICPHGPGYTTDGRDIDECKVMPNLCTN--GQCINTMGSFRCFCKVGYTTDISGTSCID  2490

Query  104   INECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSN  163
             ++ECS +   C  N  C N +G  Q C C +G+    D     C+D++EC      C   
Sbjct  2491  LDECSQSPKPC--NYICKNTEGSYQ-CSCPRGYVLQED--GKTCKDLDECQTKQHNC--Q  2543

Query  164   SVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQ  223
              +C N  G + C+C  GF      + C+  + CG+    C      C   PGSF CEC +
Sbjct  2544  FLCVNTLGGFTCKCPPGFT--QHHTACIDNNECGSQPLLCGGK-GICQNTPGSFSCECQR  2600

Query  224   GFRGAGTVNTCE  235
             GF    T   CE
Sbjct  2601  GFSLDATGLNCE  2612


 Score = 67.4 bits (163),  Expect = 4e-11, Method: Compositional matrix adjust.
 Identities = 56/148 (37%), Positives = 71/148 (47%), Gaps = 11/148 (7%)

Query  46   KGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKDGV-CID  103
             G    G+ ++    DI+ECA   D C    G C N+ GS+ C C   Y  +  G  CID
Sbjct  752  HGLCSSGVGITVDGRDINECALDPDICAN--GICENLRGSYRCNCNSGYEPDASGRNCID  809

Query  104  INECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSN  163
            I+EC  NR  CD N  C N  G    C C  G+    +     C DINEC  NP +   N
Sbjct  810  IDECLVNRLLCD-NGLCRNTPGSYS-CTCPPGYVFRTETE--TCEDINECESNPCV---N  862

Query  164  SVCTNLAGSYKCECSAGFEPDSSGSGCV  191
              C N  GS+ CECS G +  S+G  C+
Sbjct  863  GACRNNLGSFNCECSPGSKLSSTGLICI  890


 Score = 63.9 bits (154),  Expect = 5e-10, Method: Compositional matrix adjust.
 Identities = 55/156 (35%), Positives = 79/156 (50%), Gaps = 14/156 (8%)

Query  79    CVNIPGSFTCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTG  138
             C NIPG FT           G  +DI+EC    G C  N  CIN  G  + C+C  G++ 
Sbjct  1790  CGNIPG-FT------FDIHTGKAVDIDECKEIPGIC-ANGVCINQIGSFR-CECPTGFSY  1840

Query  139   NNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGT  198
             N+    + C DI+EC+   ++C  N+ C N  GSY+CEC+AGF+   +G+ CV  + C  
Sbjct  1841  NDLL--LVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGA-CVDRNECLE  1897

Query  199   GKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTC  234
               N C      C  + GS++C C  GF+ +     C
Sbjct  1898  IPNVCS--HGLCVDLQGSYQCICHNGFKASQDQTMC  1931


 Score = 57.8 bits (138),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 37/99 (37%), Positives = 56/99 (56%), Gaps = 6/99 (6%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP--YRQEK  97
             + C C  G+  +       C D+DECA+GL +C+ +G  C N+ G+F C C P   R+  
Sbjct  2274  YECTCPIGYALR--EDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPD  2331

Query  98    DGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGW  136
                C+D NEC T  G C EN  C+N+ G  + C+C++G+
Sbjct  2332  GEGCVDENECRTKPGIC-ENGRCVNIIGSYR-CECNEGF  2368


 Score = 55.1 bits (131),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 62/232 (26%), Positives = 94/232 (40%), Gaps = 51/232 (21%)

Query  40    FWCACQKGFT--PQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQE-  96
             F C C  G    P G      C+D +EC      C+   G CVNI GS+ C C    Q  
Sbjct  2318  FMCICPPGMARRPDG----EGCVDENECRTKPGICEN--GRCVNIIGSYRCECNEGFQSS  2371

Query  97    ---------KDGVCI-----DINECSTNRGNCDENSDCINLDGE----------------  126
                      + G+C       I + +++  N    S+C    G                 
Sbjct  2372  SSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQ  2431

Query  127   -EQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDS  185
              +++C    G+T +        RDI+EC   P++C +N  C N  GS++C C  G+  D 
Sbjct  2432  YKKICPHGPGYTTDG-------RDIDECKVMPNLC-TNGQCINTMGSFRCFCKVGYTTDI  2483

Query  186   SGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCEPL  237
             SG+ C+  D C      C+ +   C    GS++C C +G+       TC+ L
Sbjct  2484  SGTSCIDLDECSQSPKPCNYI---CKNTEGSYQCSCPRGYVLQEDGKTCKDL  2532


 Score = 52.8 bits (125),  Expect = 1e-06, Method: Compositional matrix adjust.
 Identities = 37/106 (34%), Positives = 50/106 (47%), Gaps = 4/106 (3%)

Query  148   RDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVF  207
             +DINEC   P +C +   C N  GS+KC C++GF  D     C   D C    + C +  
Sbjct  1071  KDINECKAFPGMC-TYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGS--  1127

Query  208   AACSLVPGSFKCECIQGFR-GAGTVNTCEPLPGNEDLACTTLGLTC  252
               C   PGSF+CEC +G+  G   +  C  + G E       G TC
Sbjct  1128  GICVNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTC  1173


 Score = 46.2 bits (108),  Expect = 9e-05, Method: Compositional matrix adjust.
 Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 5/97 (5%)

Query  97   KDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNEN  156
            + G C D++EC    G C +  +CIN  G  + C+C  G      +    C DI+EC+  
Sbjct  269  RTGACQDVDECQAIPGIC-QGGNCINTVGSFE-CRCPAGH--KQSETTQKCEDIDECSII  324

Query  157  PSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTE  193
            P IC +   C+N  GSY C C  G+   + GS C+ +
Sbjct  325  PGICETGE-CSNTVGSYFCVCPRGYVTSTDGSRCIDQ  360


 Score = 44.3 bits (103),  Expect = 4e-04, Method: Compositional matrix adjust.
 Identities = 49/171 (28%), Positives = 64/171 (37%), Gaps = 26/171 (15%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDG  99
            + C C  G+  +    + TC DI+EC           G C N  GSF C C P  +    
Sbjct  832  YSCTCPPGYVFR--TETETCEDINECESN----PCVNGACRNNLGSFNCECSPGSKLSST  885

Query  100  --VCIDI-----------NECSTNRGNCDENSDCINLDGEEQLCKCHKGW------TGNN  140
              +CID            + C  N       S+C    G      C +         G  
Sbjct  886  GLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLA  945

Query  141  DKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCV  191
                V C D+NEC   P +CP N  C N  GS+ CEC  G   D +G  C+
Sbjct  946  RIKGVTCEDVNECEVFPGVCP-NGRCVNSKGSFHCECPEGLTLDGTGRVCL  995


 Score = 44.3 bits (103),  Expect = 4e-04, Method: Compositional matrix adjust.
 Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 11/97 (11%)

Query  132  CHKGWTGNNDKPNV---ACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGS  188
            C +G+      PN+   AC+D++EC   P IC   + C N  GS++C C AG +   +  
Sbjct  260  CRRGFI-----PNIRTGACQDVDECQAIPGICQGGN-CINTVGSFECRCPAGHKQSETTQ  313

Query  189  GCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGF  225
             C   D C      C+T    CS   GS+ C C +G+
Sbjct  314  KCEDIDECSIIPGICET--GECSNTVGSYFCVCPRGY  348


 Score = 41.6 bits (96),  Expect = 0.002, Method: Compositional matrix adjust.
 Identities = 51/175 (29%), Positives = 68/175 (38%), Gaps = 39/175 (22%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
             F C C  G+          C DIDECA  + NC    G CVN PG + C C P ++    
Sbjct  1512  FHCICDDGYELD--RTGGNCTDIDECADPI-NCVN--GLCVNTPGRYECNCPPDFQLNPT  1566

Query  99    GV-CID--INECSTNRGNCDENSDCIN------LDGEEQLCKCHKGWT------------  137
             GV C+D  +  C    G   + S   N      +      C   K W             
Sbjct  1567  GVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNST  1626

Query  138   --------GNNDKPN---VACRDINECNENPSICPSNSVCTNLAGSYKCECSAGF  181
                     G   +PN   +   DI+EC E P +C   + C N  GS++CEC  G+
Sbjct  1627  EYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGN-CINTFGSFQCECPQGY  1680


 Score = 40.8 bits (94),  Expect = 0.004, Method: Compositional matrix adjust.
 Identities = 29/71 (40%), Positives = 38/71 (53%), Gaps = 6/71 (8%)

Query  46    KGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEKDGVCID  103
             +GF P  I +     DIDEC +    C+  GG+C+N  GSF C C  G Y  E   +C D
Sbjct  1636  EGFRPNPITIILE--DIDECQELPGLCQ--GGNCINTFGSFQCECPQGYYLSEDTRICED  1691

Query  104   INECSTNRGNC  114
             I+EC  + G C
Sbjct  1692  IDECFAHPGVC  1702


 Score = 38.9 bits (89),  Expect = 0.015, Method: Compositional matrix adjust.
 Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 6/87 (6%)

Query  148  RDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVF  207
            + I+ C  + ++C  N  C     SY+CEC+ G++ D++G  C+  D C +  N C    
Sbjct  492  QTIDICKHHANLC-LNGRCIPTVSSYRCECNMGYKQDANGD-CIDVDECTS--NPCTN--  545

Query  208  AACSLVPGSFKCECIQGFRGAGTVNTC  234
              C   PGS+ C+C  GF+   T   C
Sbjct  546  GDCVNTPGSYYCKCHAGFQRTPTKQAC  572


> Hs15029514
Length=2809

 Score =  101 bits (252),  Expect = 2e-21, Method: Compositional matrix adjust.
 Identities = 71/193 (36%), Positives = 95/193 (49%), Gaps = 15/193 (7%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDG  99
             F C CQ G+  +    ++ C D+DEC  G  NC      C+NIPGSF+C C P       
Sbjct  1261  FVCHCQLGYMVR--KGATGCSDVDECEVGGHNCDSHA-SCLNIPGSFSCRCLPGWVGDGF  1317

Query  100   VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSI  159
              C D++EC +    C    DC+N+ G  + C C +G+ G+       C D +EC EN  +
Sbjct  1318  ECHDLDECISQEHRCSPRGDCLNVPGSYR-CTCRQGFAGDG----FFCEDRDECAENVDL  1372

Query  160   CPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKC  219
             C  N  C N  G Y+CEC  GF+P      C   D C  G N C   F +C  +PG F+C
Sbjct  1373  C-DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQG-NLC--AFGSCENLPGMFRC  1428

Query  220   ECIQGF---RGAG  229
              C  G+   RG G
Sbjct  1429  ICNGGYELDRGGG  1441


 Score = 93.2 bits (230),  Expect = 7e-19, Method: Compositional matrix adjust.
 Identities = 73/198 (36%), Positives = 100/198 (50%), Gaps = 18/198 (9%)

Query  30    HAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCG  89
             H E   S   F C CQ G+TP     ++TC+D+DEC+Q    C      C N  GSF C 
Sbjct  2376  HGECINSLGSFRCHCQAGYTPDAT--ATTCLDMDECSQVPKPCTFL---CKNTKGSFLCS  2430

Query  90    CGP-YRQEKDG-VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVAC  147
             C   Y  E+DG  C D++EC++ + NC     C+N  G    C+C  G+T ++     AC
Sbjct  2431  CPRGYLLEEDGRTCKDLDECTSRQHNC--QFLCVNTVGAFT-CRCPPGFTQHHQ----AC  2483

Query  148   RDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVF  207
              D +EC+  P  C ++  C N  GS++CEC  GF   SSG GC   + C  G + C    
Sbjct  2484  FDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC-DGPHRCQ---  2539

Query  208   AACSLVPGSFKCECIQGF  225
               C    G ++C C QGF
Sbjct  2540  HGCQNQLGGYRCSCPQGF  2557


 Score = 93.2 bits (230),  Expect = 7e-19, Method: Compositional matrix adjust.
 Identities = 72/211 (34%), Positives = 92/211 (43%), Gaps = 26/211 (12%)

Query  17    CDAGGYDHCSRVEHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKG  76
             CD G   HC+ +     C   DGF        TP       TC+D+DEC      C    
Sbjct  1207  CDQG---HCTNMPGGHRCLCYDGFM------ATPD----MRTCVDVDECDLNPHICLH--  1251

Query  77    GDCVNIPGSFTCGCGPYRQEKDGV--CIDINECSTNRGNCDENSDCINLDGEEQLCKCHK  134
             GDC N  GSF C C      + G   C D++EC     NCD ++ C+N+ G    C+C  
Sbjct  1252  GDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFS-CRCLP  1310

Query  135   GWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTED  194
             GW G+       C D++EC      C     C N+ GSY+C C  GF  D  G  C   D
Sbjct  1311  GWVGDG----FECHDLDECISQEHRCSPRGDCLNVPGSYRCTCRQGFAGD--GFFCEDRD  1364

Query  195   FCGTGKNDCDTVFAACSLVPGSFKCECIQGF  225
              C    + CD     C   PG ++CEC  GF
Sbjct  1365  ECAENVDLCDN--GQCLNAPGGYRCECEMGF  1393


 Score = 92.8 bits (229),  Expect = 8e-19, Method: Compositional matrix adjust.
 Identities = 70/197 (35%), Positives = 91/197 (46%), Gaps = 13/197 (6%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQ--EK  97
             F C C  G+   G  L   C+D+DECA+  D    +GG C N  GS+ C C P  +   K
Sbjct  1051  FECECFPGYE-SGFMLMKNCMDVDECAR--DPLLCRGGTCTNTDGSYKCQCPPGHELTAK  1107

Query  98    DGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP  157
                C DI+ECS + G C  +  C+N+ G  Q C CH G+    D+    C DINEC    
Sbjct  1108  GTACEDIDECSLSDGLC-PHGQCVNVIGAFQ-CSCHAGFQSTPDR--QGCVDINECRVQN  1163

Query  158   SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSF  217
               C  +  C N  GSY+C C  G+     G  C   D C      CD     C+ +PG  
Sbjct  1164  GGC--DVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQ--GHCTNMPGGH  1219

Query  218   KCECIQGFRGAGTVNTC  234
             +C C  GF     + TC
Sbjct  1220  RCLCYDGFMATPDMRTC  1236


 Score = 90.1 bits (222),  Expect = 6e-18, Method: Compositional matrix adjust.
 Identities = 69/187 (36%), Positives = 89/187 (47%), Gaps = 13/187 (6%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
             F C C  GF    I L+  C D+DEC      C+Q   DC+NIPGS+ C C   Y+    
Sbjct  1744  FRCECPAGFNYNSILLA--CEDVDECGSRESPCQQNA-DCINIPGSYRCKCTRGYKLSPG  1800

Query  99    GVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPS  158
             G C+  NEC      C  + DC++ +G   +C CH+G+  + D+    C DI+EC+  P 
Sbjct  1801  GACVGQNECREIPNVC-SHGDCMDTEGS-YMCLCHRGFQASADQ--TLCMDIDECDRQPC  1856

Query  159   ICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFK  218
                 N  C N+ GSY C C  GF    +G  CV  D C T        F  C    GSF 
Sbjct  1857  ---GNGTCKNIIGSYNCLCFPGFVVTHNGD-CVDFDECTTLVGQV-CRFGHCLNTAGSFH  1911

Query  219   CECIQGF  225
             C C  GF
Sbjct  1912  CLCQDGF  1918


 Score = 88.6 bits (218),  Expect = 2e-17, Method: Compositional matrix adjust.
 Identities = 71/207 (34%), Positives = 98/207 (47%), Gaps = 16/207 (7%)

Query  22    YDHCSRVEHAES--CQSGDG-FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGD  78
              D CS+V    +  C++  G F C+C +G+  +      TC D+DEC     NC+     
Sbjct  2406  MDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLE--EDGRTCKDLDECTSRQHNCQFL---  2460

Query  79    CVNIPGSFTCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTG  138
             CVN  G+FTC C P   +    C D +ECS   G C  +  C N  G  + C+CH+G+T 
Sbjct  2461  CVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFR-CECHQGFTL  2519

Query  139   NNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGT  198
              +      C D+NEC + P  C     C N  G Y+C C  GF   S  + CV E+ C  
Sbjct  2520  VSS--GHGCEDVNEC-DGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECAL  2574

Query  199   GKNDCDTVFAACSLVPGSFKCECIQGF  225
                 C +  A+C    G F+C C  GF
Sbjct  2575  SPPTCGS--ASCRNTLGGFRCVCPSGF  2599


 Score = 87.4 bits (215),  Expect = 4e-17, Method: Compositional matrix adjust.
 Identities = 72/208 (34%), Positives = 96/208 (46%), Gaps = 21/208 (10%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDG  99
             F CAC  GF          C DIDEC    D C Q  G CVN PGSF C C P  +    
Sbjct  1009  FHCACAGGFALDA--QERNCTDIDECRISPDLCGQ--GTCVNTPGSFECECFPGYESGFM  1064

Query  100   V---CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNEN  156
             +   C+D++EC+ +   C     C N DG  + C+C  G          AC DI+EC+ +
Sbjct  1065  LMKNCMDVDECARDPLLC-RGGTCTNTDGSYK-CQCPPGH--ELTAKGTACEDIDECSLS  1120

Query  157   PSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGS  216
               +CP +  C N+ G+++C C AGF+      GCV  + C      CD     C    GS
Sbjct  1121  DGLCP-HGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDV---HCINTEGS  1176

Query  217   FKCECIQGF------RGAGTVNTCEPLP  238
             ++C C QG+      R    V+ CE  P
Sbjct  1177  YRCSCGQGYSLMPDGRACADVDECEENP  1204


 Score = 84.7 bits (208),  Expect = 3e-16, Method: Compositional matrix adjust.
 Identities = 76/233 (32%), Positives = 106/233 (45%), Gaps = 21/233 (9%)

Query  5     RLAAMGGKSSTPCDAGGYDHCSRVEHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDE  64
             R  A G      C+ GG++  S   HA        F C C  G+   G      C D+DE
Sbjct  1272  RKGATGCSDVDECEVGGHNCDS---HASCLNIPGSFSCRCLPGWVGDGFE----CHDLDE  1324

Query  65    CAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLD  124
             C      C  +G DC+N+PGS+ C C          C D +EC+ N   CD N  C+N  
Sbjct  1325  CISQEHRCSPRG-DCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCD-NGQCLNAP  1382

Query  125   GEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPD  184
             G  + C+C  G+    D  + AC+D++EC +  ++C   S C NL G ++C C+ G+E D
Sbjct  1383  GGYR-CECEMGFDPTED--HRACQDVDECAQG-NLCAFGS-CENLPGMFRCICNGGYELD  1437

Query  185   SSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFR----GAGTVNT  233
               G  C   + C    N    +   C   PGS+ C C Q F     G G V+T
Sbjct  1438  RGGGNCTDINECADPVN---CINGVCINTPGSYLCSCPQDFELNPSGVGCVDT  1487


 Score = 78.6 bits (192),  Expect = 2e-14, Method: Compositional matrix adjust.
 Identities = 73/210 (34%), Positives = 100/210 (47%), Gaps = 20/210 (9%)

Query  34    CQSGDG-FWCACQKGFTPQ--GINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC  90
             C + DG F C C  G++    GIN    C+D DEC+ G   C Q  G C N+ G F C C
Sbjct  2100  CVNTDGSFRCECPFGYSLDFTGIN----CVDTDECSVG-HPCGQ--GTCTNVIGGFECAC  2152

Query  91    GP-YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRD  149
                +       C DI+ECS N   C     C N +G   LC C  G+T   D     CRD
Sbjct  2153  ADGFEPGLMMTCEDIDECSLNPLLCAFR--CHNTEGS-YLCTCPAGYTLRED--GAMCRD  2207

Query  150   INECNENPSICPSNSV-CTNLAGSYKCECSAGFEP-DSSGSGCVTEDFCGTGKNDCDTVF  207
             ++EC +    C +  + C NL G++ C C  G  P   SG GC  ++ C    + C  V 
Sbjct  2208  VDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLC--VN  2265

Query  208   AACSLVPGSFKCECIQGFRGAGTVNTCEPL  237
               C    GSF+C+C +GF+ + T+  C  +
Sbjct  2266  GRCVNTAGSFRCDCDEGFQPSPTLTECHDI  2295


 Score = 78.2 bits (191),  Expect = 3e-14, Method: Compositional matrix adjust.
 Identities = 67/188 (35%), Positives = 92/188 (48%), Gaps = 18/188 (9%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEK--  97
            + C C  G+T    ++   CID+DEC      C    GDCVNIPG++ C C P  Q    
Sbjct  431  YRCECNVGYTQ---DVRGECIDVDECTS--SPCHH--GDCVNIPGTYHCRCYPGFQATPT  483

Query  98   DGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP  157
               C+D++EC  + G C     C+N +G  Q C C+ G+  + D  N  C D NEC  + 
Sbjct  484  RQACVDVDECIVSGGLCHLGR-CVNTEGSFQ-CVCNAGFELSPDGKN--CVDHNECATS-  538

Query  158  SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSF  217
            ++C  N VC N  GS+ C C  GF     G  C+  D C T       V   C+   GSF
Sbjct  539  TMC-VNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPG---ICVNGHCTNTEGSF  594

Query  218  KCECIQGF  225
            +C+C+ G 
Sbjct  595  RCQCLGGL  602


 Score = 75.5 bits (184),  Expect = 2e-13, Method: Compositional matrix adjust.
 Identities = 79/236 (33%), Positives = 104/236 (44%), Gaps = 43/236 (18%)

Query  33    SCQSGDG-FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCG  91
             +CQ+ +G F C C  GF  Q    S  CIDIDEC++  + C    G C N PGSF C C 
Sbjct  1944  TCQNLEGSFRCICPPGFQVQ----SDHCIDIDECSEEPNLCLF--GTCTNSPGSFQCLCP  1997

Query  92    P--YRQEKDGVCIDINE--CSTNRGNCDENSDCINLDGEEQLCKCHK----GW-------  136
             P     +    C D  +  C T R    + S     +  +  C C K    GW       
Sbjct  1998  PGFVLSDNGHRCFDTRQSFCFT-RFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELC  2056

Query  137   ---------------TGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGF  181
                             G    P+ +  D+NEC ENP +C +N VC N  GS++CEC  G+
Sbjct  2057  PQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVC-TNGVCVNTDGSFRCECPFGY  2115

Query  182   EPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCEPL  237
               D +G  CV  D C  G + C      C+ V G F+C C  GF   G + TCE +
Sbjct  2116  SLDFTGINCVDTDECSVG-HPCGQ--GTCTNVIGGFECACADGFE-PGLMMTCEDI  2167


 Score = 71.2 bits (173),  Expect = 3e-12, Method: Compositional matrix adjust.
 Identities = 63/183 (34%), Positives = 84/183 (45%), Gaps = 23/183 (12%)

Query  61    DIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDGV---CIDINECSTNRGNCDEN  117
             D++ECA+    C    G CVN  GSF C C P+    D     C+D +ECS     C + 
Sbjct  2084  DVNECAENPGVCTN--GVCVNTDGSFRCEC-PFGYSLDFTGINCVDTDECSVGH-PCGQG  2139

Query  118   SDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCEC  177
             + C N+ G  + C C  G+        + C DI+EC+ NP +C     C N  GSY C C
Sbjct  2140  T-CTNVIGGFE-CACADGF---EPGLMMTCEDIDECSLNPLLCAFR--CHNTEGSYLCTC  2192

Query  178   SAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCEPL  237
              AG+     G+ C   D C  G+ DC      C  + G+F C C  G R         PL
Sbjct  2193  PAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMR---------PL  2243

Query  238   PGN  240
             PG+
Sbjct  2244  PGS  2246


 Score = 69.3 bits (168),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 55/165 (33%), Positives = 80/165 (48%), Gaps = 13/165 (7%)

Query  62   IDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKDGVCIDINECSTNRGNCDENSDC  120
            ID C    + C    G C+  P S+ C C   Y Q+  G CID++EC+++  +   + DC
Sbjct  409  IDICRHFTNLCLN--GRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCH---HGDC  463

Query  121  INLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAG  180
            +N+ G    C+C+ G+     +   AC D++EC  +  +C     C N  GS++C C+AG
Sbjct  464  VNIPGTYH-CRCYPGFQATPTR--QACVDVDECIVSGGLCHLGR-CVNTEGSFQCVCNAG  519

Query  181  FEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGF  225
            FE    G  CV  + C T       V   C    GSF C C  GF
Sbjct  520  FELSPDGKNCVDHNECATSTM---CVNGVCLNEDGSFSCLCKPGF  561


 Score = 68.6 bits (166),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 82/226 (36%), Positives = 98/226 (43%), Gaps = 48/226 (21%)

Query  34   CQSGDG-FWCACQKGF--TPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC  90
            C + DG F C C+ GF   P G      C+DIDEC Q    C    G C N  GSF C C
Sbjct  546  CLNEDGSFSCLCKPGFLLAPGG----HYCMDIDEC-QTPGICVN--GHCTNTEGSFRCQC  598

Query  91   -GPYRQEKDG-VCIDINECSTNRGNCDENSD--------------CINLD---GEE-QLC  130
             G      DG VC+D +  ST  G  ++ S               C N D   GE  QLC
Sbjct  599  LGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLC  658

Query  131  K----------CHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAG  180
                       C  G     D      RDINEC  +P +C +N VC NL GSY+C C+ G
Sbjct  659  PAKNSAEFQALCSSGLGITTDG-----RDINECALDPEVC-ANGVCENLRGSYRCVCNLG  712

Query  181  FEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFR  226
            +E  +SG  C   D C      CD  +  C   PGS+ C C  GF 
Sbjct  713  YEAGASGKDCTDVDECALNSLLCDNGW--CQNSPGSYSCSCPPGFH  756


 Score = 68.2 bits (165),  Expect = 3e-11, Method: Compositional matrix adjust.
 Identities = 73/261 (27%), Positives = 104/261 (39%), Gaps = 35/261 (13%)

Query  61    DIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEKDGVCIDINECSTNRGNCDENS  118
             D++EC      C    G C N  GSF C C  G     ++  C DI+EC  +   C + +
Sbjct  986   DVNECKVFPGLCTH--GTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGT  1043

Query  119   DCINLDGEEQLCKCHKGW-TGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCEC  177
              C+N  G  + C+C  G+ +G     N  C D++EC  +P +C     CTN  GSYKC+C
Sbjct  1044  -CVNTPGSFE-CECFPGYESGFMLMKN--CMDVDECARDPLLC-RGGTCTNTDGSYKCQC  1098

Query  178   SAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGF------RGAGTV  231
               G E  + G+ C   D C      C      C  V G+F+C C  GF      +G   +
Sbjct  1099  PPGHELTAKGTACEDIDECSLSDGLCP--HGQCVNVIGAFQCSCHAGFQSTPDRQGCVDI  1156

Query  232   NTCEPLPGNEDLACTTL-----------------GLTCGDYKYCTKSTTQAGLWECTDKA  274
             N C    G  D+ C                    G  C D   C ++        CT+  
Sbjct  1157  NECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMP  1216

Query  275   ASEQLAVFIANGATSDTPSWV  295
                +   +    AT D  + V
Sbjct  1217  GGHRCLCYDGFMATPDMRTCV  1237


 Score = 64.3 bits (155),  Expect = 4e-10, Method: Compositional matrix adjust.
 Identities = 63/183 (34%), Positives = 89/183 (48%), Gaps = 21/183 (11%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
             + C C  GF    +  +  C+D DEC   +     + G C+N  GSF C C   +    D
Sbjct  1868  YNCLCFPGFV---VTHNGDCVDFDECTTLVGQ-VCRFGHCLNTAGSFHCLCQDGFELTAD  1923

Query  99    GV-CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP  157
             G  C+D NEC +  G C   + C NL+G  + C C  G+   +D     C DI+EC+E P
Sbjct  1924  GKNCVDTNECLSLAGTCLPGT-CQNLEGSFR-CICPPGFQVQSDH----CIDIDECSEEP  1977

Query  158   SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAA--CSLVPG  215
             ++C   + CTN  GS++C C  GF    +G  C       T ++ C T F A  CS VP 
Sbjct  1978  NLCLFGT-CTNSPGSFQCLCPPGFVLSDNGHRCFD-----TRQSFCFTRFEAGKCS-VPK  2030

Query  216   SFK  218
             +F 
Sbjct  2031  AFN  2033


 Score = 60.1 bits (144),  Expect = 6e-09, Method: Compositional matrix adjust.
 Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 7/133 (5%)

Query  102   IDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICP  161
             +DI+EC      C  N  CIN  G  + C+C  G+  N +   +AC D++EC    S C 
Sbjct  1720  LDIDECGEIPAIC-ANGICINQIGSFR-CECPAGF--NYNSILLACEDVDECGSRESPCQ  1775

Query  162   SNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCEC  221
              N+ C N+ GSY+C+C+ G++  S G  CV ++ C    N C      C    GS+ C C
Sbjct  1776  QNADCINIPGSYRCKCTRGYKL-SPGGACVGQNECREIPNVCS--HGDCMDTEGSYMCLC  1832

Query  222   IQGFRGAGTVNTC  234
              +GF+ +     C
Sbjct  1833  HRGFQASADQTLC  1845


 Score = 58.9 bits (141),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 60/183 (32%), Positives = 79/183 (43%), Gaps = 37/183 (20%)

Query  34   CQSGDG-FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP  92
            CQ+  G + C+C  GF       +  C D+DEC           G C N+ GS+TC CGP
Sbjct  740  CQNSPGSYSCSCPPGF--HFWQDTEICKDVDECLSS----PCVSGVCRNLAGSYTCKCGP  793

Query  93   -YRQEKDG-VCIDINECSTNRGNC---DENSDC-INLDGEEQLCKC----HKGW------  136
              R +  G  C+D     + +G C    + S C +NL G     +C       W      
Sbjct  794  GSRLDPSGTFCLD-----STKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCER  848

Query  137  --------TGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGS  188
                     G      V C D+NEC   P +CP N  C N AGS++CEC  G   D+SG 
Sbjct  849  CEIDPACARGFARMTGVTCDDVNECESFPGVCP-NGRCVNTAGSFRCECPEGLMLDASGR  907

Query  189  GCV  191
             CV
Sbjct  908  LCV  910


 Score = 58.5 bits (140),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 51/142 (35%), Positives = 72/142 (50%), Gaps = 11/142 (7%)

Query  52   GINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKDGV-CIDINECST  109
            G+ +++   DI+ECA   + C    G C N+ GS+ C C   Y     G  C D++EC+ 
Sbjct  673  GLGITTDGRDINECALDPEVCAN--GVCENLRGSYRCVCNLGYEAGASGKDCTDVDECAL  730

Query  110  NRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNL  169
            N   CD N  C N  G    C C  G+    D     C+D++EC  +P +   + VC NL
Sbjct  731  NSLLCD-NGWCQNSPGSYS-CSCPPGFHFWQDTE--ICKDVDECLSSPCV---SGVCRNL  783

Query  170  AGSYKCECSAGFEPDSSGSGCV  191
            AGSY C+C  G   D SG+ C+
Sbjct  784  AGSYTCKCGPGSRLDPSGTFCL  805


 Score = 51.2 bits (121),  Expect = 3e-06, Method: Compositional matrix adjust.
 Identities = 61/217 (28%), Positives = 85/217 (39%), Gaps = 45/217 (20%)

Query  43    ACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEKDGV  100
             AC +GF         TC D++EC      C    G CVN  GSF C C  G        +
Sbjct  854   ACARGFARM---TGVTCDDVNECESFPGVCPN--GRCVNTAGSFRCECPEGLMLDASGRL  908

Query  101   CIDIN--ECSTNRGNCDENSDCINLDGEEQL--CKCHKG--W------------------  136
             C+D+    C       DE+   + L G+ ++  C C  G  W                  
Sbjct  909   CVDVRLEPCFLRW---DEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASL  965

Query  137   ----TGNNDKPNVACR----DINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGS  188
                  G   +  ++ R    D+NEC   P +C ++  C N  GS+ C C+ GF  D+   
Sbjct  966   CPRGLGFASRDFLSGRPFYKDVNECKVFPGLC-THGTCRNTVGSFHCACAGGFALDAQER  1024

Query  189   GCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGF  225
              C   D C    + C      C   PGSF+CEC  G+
Sbjct  1025  NCTDIDECRISPDLCGQ--GTCVNTPGSFECECFPGY  1059


 Score = 49.7 bits (117),  Expect = 1e-05, Method: Compositional matrix adjust.
 Identities = 41/127 (32%), Positives = 60/127 (47%), Gaps = 12/127 (9%)

Query  31    AESCQSGDG-FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCG  89
             A  C + +G + C C  G+T +     + C D+DECA G  +C  +G +C N+ G+F C 
Sbjct  2178  AFRCHNTEGSYLCTCPAGYTLR--EDGAMCRDVDECADGQQDCHARGMECKNLIGTFACV  2235

Query  90    CGPYRQEKDGV---CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVA  146
             C P  +   G    C D NEC      C  N  C+N  G  + C C +G+      P + 
Sbjct  2236  CPPGMRPLPGSGEGCTDDNECHAQPDLC-VNGRCVNTAGSFR-CDCDEGF---QPSPTLT  2290

Query  147   -CRDINE  152
              C DI +
Sbjct  2291  ECHDIRQ  2297


 Score = 48.9 bits (115),  Expect = 1e-05, Method: Compositional matrix adjust.
 Identities = 64/220 (29%), Positives = 87/220 (39%), Gaps = 37/220 (16%)

Query  46    KGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP--YRQEKDGVCID  103
             +GF P  I +     DIDEC +    C+  GGDCVN  GSF C C P  +  E   +C D
Sbjct  1550  EGFQPNRITVILE--DIDECQELPGLCQ--GGDCVNTFGSFQCECPPGYHLSEHTRICED  1605

Query  104   INECSTNRGNCDENSDCIN----------------------LDGEEQLCKCHKGWTGNND  141
             I+ECST+ G C   + C N                      +D  + +C  H   T  N+
Sbjct  1606  IDECSTHSGICGPGT-CYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNE  1664

Query  142   KPNVACRDINECNENPSIC---PSNSVCTNLAGSYKCEC---SAGFEPDSSGSGCVTEDF  195
                   R +  C+ N       P  +  T ++  Y+  C   + GF  D      +  D 
Sbjct  1665  LAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDE  1724

Query  196   CGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCE  235
             CG     C      C    GSF+CEC  GF     +  CE
Sbjct  1725  CGEIPAICAN--GICINQIGSFRCECPAGFNYNSILLACE  1762


 Score = 43.1 bits (100),  Expect = 9e-04, Method: Compositional matrix adjust.
 Identities = 48/171 (28%), Positives = 73/171 (42%), Gaps = 22/171 (12%)

Query  13    SSTPCDAGGYDHCSRVEHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNC  72
             S+ P   G + HC     +        F C C +GFT   ++    C D++EC  G   C
Sbjct  2490  SAQPGPCGAHGHCHNTPGS--------FRCECHQGFTL--VSSGHGCEDVNEC-DGPHRC  2538

Query  73    KQKGGDCVNIPGSFTCGC--GPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLC  130
             +     C N  G + C C  G  +  +   C+D NEC+ +   C   S C N  G  + C
Sbjct  2539  QHG---CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSAS-CRNTLGGFR-C  2593

Query  131   KCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGF  181
              C  G+  + D+    C+D++EC       P +  C N  G + C C  G+
Sbjct  2594  VCPSGF--DFDQALGGCQDVDECAGRRG--PCSYSCANTPGGFLCGCPQGY  2640


 Score = 42.4 bits (98),  Expect = 0.002, Method: Compositional matrix adjust.
 Identities = 62/230 (26%), Positives = 80/230 (34%), Gaps = 45/230 (19%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
             F C C  G+          C DI+ECA  + NC    G C+N PGS+ C C   +     
Sbjct  1426  FRCICNGGYELD--RGGGNCTDINECADPV-NCIN--GVCINTPGSYLCSCPQDFELNPS  1480

Query  99    GV-CIDINE-------------------------------CSTNR--GNCDENSDCINLD  124
             GV C+D                                  CS  R  GN  E     N  
Sbjct  1481  GVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTT  1540

Query  125   GEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPD  184
                 LC   +G+  N  +  V   DI+EC E P +C     C N  GS++CEC  G+   
Sbjct  1541  EYRTLCPGGEGFQPN--RITVILEDIDECQELPGLCQGGD-CVNTFGSFQCECPPGYHLS  1597

Query  185   SSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTC  234
                  C   D C T    C      C    G++ C C   +      N C
Sbjct  1598  EHTRICEDIDECSTHSGICGP--GTCYNTLGNYTCVCPAEYLQVNGGNNC  1645


 Score = 37.7 bits (86),  Expect = 0.036, Method: Compositional matrix adjust.
 Identities = 23/67 (34%), Positives = 34/67 (50%), Gaps = 11/67 (16%)

Query  132  CHKGWTGNNDKPNV---ACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGS  188
            C +G+      PN+   AC+D++EC   P +C   S C N+ GS+ C C  G     S +
Sbjct  232  CRRGFI-----PNIHTGACQDVDECQAVPGLCQGGS-CVNMVGSFHCRCPVGHRLSDSSA  285

Query  189  GCVTEDF  195
             C  ED+
Sbjct  286  AC--EDY  290


 Score = 37.0 bits (84),  Expect = 0.053, Method: Compositional matrix adjust.
 Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 6/87 (6%)

Query  148  RDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVF  207
            + I+ C    ++C  N  C     SY+CEC+ G+  D  G  C+  D C +         
Sbjct  407  QTIDICRHFTNLC-LNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDECTSSP----CHH  460

Query  208  AACSLVPGSFKCECIQGFRGAGTVNTC  234
              C  +PG++ C C  GF+   T   C
Sbjct  461  GDCVNIPGTYHCRCYPGFQATPTRQAC  487


 Score = 33.1 bits (74),  Expect = 0.89, Method: Compositional matrix adjust.
 Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 4/47 (8%)

Query  44   CQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC  90
            C++GF P     +  C D+DEC      C+  GG CVN+ GSF C C
Sbjct  232  CRRGFIPN--IHTGACQDVDECQAVPGLCQ--GGSCVNMVGSFHCRC  274


> Hs20549163
Length=2871

 Score =  100 bits (250),  Expect = 3e-21, Method: Compositional matrix adjust.
 Identities = 71/186 (38%), Positives = 94/186 (50%), Gaps = 12/186 (6%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDG  99
             F C C  G++  G    + C DI+EC  G  NC  K   C N  GSF C C P       
Sbjct  1303  FICHCDMGYS--GKKGKTGCTDINECEIGAHNCG-KHAVCTNTAGSFKCSCSPGWIGDGI  1359

Query  100   VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSI  159
              C D++ECS     C +++DC N  G  + C C +G+TG+       C D++EC+EN ++
Sbjct  1360  KCTDLDECSNGTHMCSQHADCKNTMGSYR-CLCKEGYTGDG----FTCTDLDECSENLNL  1414

Query  160   CPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKC  219
             C  N  C N  G Y+CEC  GF P + G  C   D C    N C  VF  C  +PG F+C
Sbjct  1415  C-GNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSL-PNIC--VFGTCHNLPGLFRC  1470

Query  220   ECIQGF  225
             EC  G+
Sbjct  1471  ECEIGY  1476


 Score = 94.7 bits (234),  Expect = 2e-19, Method: Compositional matrix adjust.
 Identities = 73/192 (38%), Positives = 95/192 (49%), Gaps = 13/192 (6%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEK  97
             + C+CQ GF    +    +C DIDEC    + C   GG C NIPG + C C  G    E 
Sbjct  1219  YECSCQPGFAL--MPDQRSCTDIDECEDNPNICD--GGQCTNIPGEYRCLCYDGFMASED  1274

Query  98    DGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP  157
                C+D+NEC  N   C   + C N  G   +C C  G++G   K    C DINEC    
Sbjct  1275  MKTCVDVNECDLNPNICLSGT-CENTKGS-FICHCDMGYSGKKGK--TGCTDINECEIGA  1330

Query  158   SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSF  217
               C  ++VCTN AGS+KC CS G+  D  G  C   D C  G + C +  A C    GS+
Sbjct  1331  HNCGKHAVCTNTAGSFKCSCSPGWIGD--GIKCTDLDECSNGTHMC-SQHADCKNTMGSY  1387

Query  218   KCECIQGFRGAG  229
             +C C +G+ G G
Sbjct  1388  RCLCKEGYTGDG  1399


 Score = 87.0 bits (214),  Expect = 5e-17, Method: Compositional matrix adjust.
 Identities = 68/197 (34%), Positives = 95/197 (48%), Gaps = 18/197 (9%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEK  97
             + C C+ G+TP     S  C+D++EC Q    C      C N  GS+ C C  G   QE 
Sbjct  2425  YHCICKTGYTPDITGTS--CVDLNECNQAPKPCNFI---CKNTEGSYQCSCPKGYILQED  2479

Query  98    DGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP  157
                C D++EC+T + NC     C+N  G    CKC  G+T    + + +C D NEC  + 
Sbjct  2480  GRSCKDLDECATKQHNC--QFLCVNTIGG-FTCKCPPGFT----QHHTSCIDNNECTSDI  2532

Query  158   SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSF  217
             ++C S  +C N  GS+ CEC  GF  D +GS C   D C  G + C      C  + G +
Sbjct  2533  NLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDEC-EGNHRCQ---HGCQNIIGGY  2588

Query  218   KCECIQGFRGAGTVNTC  234
             +C C QG+      N C
Sbjct  2589  RCSCPQGYLQHYQWNQC  2605


 Score = 84.3 bits (207),  Expect = 3e-16, Method: Compositional matrix adjust.
 Identities = 64/153 (41%), Positives = 81/153 (52%), Gaps = 13/153 (8%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
             F C C  GF    ++ ++ CID+DECA G  N   + G C+N  GSF C C   Y    D
Sbjct  1912  FNCRCNHGFI---LSHNNDCIDVDECASGNGN-LCRNGQCINTVGSFQCQCNEGYEVAPD  1967

Query  99    G-VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP  157
             G  C+DINEC      C   + C NLDG  + C C  G++  N+K    C DI+EC E P
Sbjct  1968  GRTCVDINECLLEPRKCAPGT-CQNLDGSYR-CICPPGYSLQNEK----CEDIDECVEEP  2021

Query  158   SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGC  190
              IC +   C+N  GS+KC C  GF   SSG  C
Sbjct  2022  EIC-ALGTCSNTEGSFKCLCPEGFSLSSSGRRC  2053


 Score = 82.4 bits (202),  Expect = 1e-15, Method: Compositional matrix adjust.
 Identities = 68/197 (34%), Positives = 94/197 (47%), Gaps = 14/197 (7%)

Query  29    EHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTC  88
             +HA    +   F C+C  G+   GI     C D+DEC+ G   C Q   DC N  GS+ C
Sbjct  1335  KHAVCTNTAGSFKCSCSPGWIGDGIK----CTDLDECSNGTHMCSQH-ADCKNTMGSYRC  1389

Query  89    GCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACR  148
              C          C D++ECS N   C  N  C+N  G  + C+C  G+  + D    AC 
Sbjct  1390  LCKEGYTGDGFTCTDLDECSENLNLCG-NGQCLNAPGGYR-CECDMGFVPSAD--GKACE  1445

Query  149   DINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFA  208
             DI+EC+  P+IC   + C NL G ++CEC  G+E D SG  C   + C    +    +  
Sbjct  1446  DIDECSL-PNICVFGT-CHNLPGLFRCECEIGYELDRSGGNCTDVNEC---LDPTTCISG  1500

Query  209   ACSLVPGSFKCECIQGF  225
              C   PGS+ C+C   F
Sbjct  1501  NCVNTPGSYICDCPPDF  1517


 Score = 79.0 bits (193),  Expect = 1e-14, Method: Compositional matrix adjust.
 Identities = 66/186 (35%), Positives = 90/186 (48%), Gaps = 17/186 (9%)

Query  60    IDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDGVCIDINECSTNRGNCDENSD  119
             +D+DEC +  D CK   G C+N  GS+ C C          C+D +ECS   GN   N  
Sbjct  2126  VDMDECKE-PDVCKH--GQCINTDGSYRCECPFGYILAGNECVDTDECSV--GNPCGNGT  2180

Query  120   CINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSA  179
             C N+ G  + C C +G+      P + C DINEC +NP +C     C N  GSY+C+C  
Sbjct  2181  CKNVIGGFE-CTCEEGF---EPGPMMTCEDINECAQNPLLCAFR--CVNTYGSYECKCPV  2234

Query  180   GFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFR----GAGTV--NT  233
             G+        C  ED C  GK+DC      C  + G++ C C  G++    G G V  N 
Sbjct  2235  GYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENE  2294

Query  234   CEPLPG  239
             C+  PG
Sbjct  2295  CQTKPG  2300


 Score = 78.2 bits (191),  Expect = 3e-14, Method: Compositional matrix adjust.
 Identities = 71/197 (36%), Positives = 90/197 (45%), Gaps = 16/197 (8%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
             F C C  GF      L   C DIDEC  G     Q+  +C+N  GS+ C C P YR    
Sbjct  1789  FRCECPVGFFYNDKLL--VCEDIDECQNGP--VCQRNAECINTAGSYRCDCKPGYRFTST  1844

Query  99    GVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPS  158
             G C D NEC      C  +  CI+  G    C CH G+  N+D+    C DINEC  +  
Sbjct  1845  GQCNDRNECQEIPNIC-SHGQCIDTVG-SFYCLCHTGFKTNDDQ--TMCLDINECERDAC  1900

Query  159   ICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGK-NDCDTVFAACSLVPGSF  217
                 N  C N  GS+ C C+ GF   S  + C+  D C +G  N C      C    GSF
Sbjct  1901  ---GNGTCRNTIGSFNCRCNHGFIL-SHNNDCIDVDECASGNGNLCRN--GQCINTVGSF  1954

Query  218   KCECIQGFRGAGTVNTC  234
             +C+C +G+  A    TC
Sbjct  1955  QCQCNEGYEVAPDGRTC  1971


 Score = 77.4 bits (189),  Expect = 4e-14, Method: Compositional matrix adjust.
 Identities = 81/273 (29%), Positives = 117/273 (42%), Gaps = 20/273 (7%)

Query  46    KGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKDGV-CID  103
             K   P G    +   DIDEC    D C+   G+CVN  GS+ C C   Y  +  G  C+D
Sbjct  2387  KKLCPHGRGFMTNGADIDECKVIHDVCRN--GECVNDRGSYHCICKTGYTPDITGTSCVD  2444

Query  104   INECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSN  163
             +NEC+     C  N  C N +G  Q C C KG+    D    +C+D++EC      C   
Sbjct  2445  LNECNQAPKPC--NFICKNTEGSYQ-CSCPKGYILQED--GRSCKDLDECATKQHNC--Q  2497

Query  164   SVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQ  223
              +C N  G + C+C  GF      + C+  + C +  N C +    C   PGSF CEC +
Sbjct  2498  FLCVNTIGGFTCKCPPGFT--QHHTSCIDNNECTSDINLCGSK-GICQNTPGSFTCECQR  2554

Query  224   GFRGAGTVNTCEPL---PGNEDLACTTLGLTCGDYKYCTKSTTQAGLW-ECTDKAASEQL  279
             GF    T ++CE +    GN         +  G    C +   Q   W +C D+  +E L
Sbjct  2555  GFSLDQTGSSCEDVDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDE--NECL  2612

Query  280   AVFIANGATSDTPSWVWAVVVLSTIALILISGG  312
             +  I  GA+       +  +  +       SGG
Sbjct  2613  SAHICGGASCHNTLGSYKCMCPAGFQYEQFSGG  2645


 Score = 77.0 bits (188),  Expect = 5e-14, Method: Compositional matrix adjust.
 Identities = 72/211 (34%), Positives = 95/211 (45%), Gaps = 27/211 (12%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-----YR  94
             F C C  GF     +    C DIDEC    D C +  G CVN PG F C C       + 
Sbjct  1051  FKCRCDSGFALD--SEERNCTDIDECRISPDLCGR--GQCVNTPGDFECKCDEGYESGFM  1106

Query  95    QEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNV-ACRDINEC  153
               K+  C+DI+EC  +   C     C N +G  + C+C  G   +   PN+ AC DINEC
Sbjct  1107  MMKN--CMDIDECQRDPLLC-RGGVCHNTEGSYR-CECPPG---HQLSPNISACIDINEC  1159

Query  154   NENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLV  213
               +  +CP N  C NL G Y+C C+ G+        CV  D C      C+T    C+  
Sbjct  1160  ELSAHLCP-NGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETF---CTNS  1215

Query  214   PGSFKCECIQGF------RGAGTVNTCEPLP  238
              GS++C C  GF      R    ++ CE  P
Sbjct  1216  EGSYECSCQPGFALMPDQRSCTDIDECEDNP  1246


 Score = 75.9 bits (185),  Expect = 1e-13, Method: Compositional matrix adjust.
 Identities = 75/215 (34%), Positives = 103/215 (47%), Gaps = 34/215 (15%)

Query  23   DHCSRVEHAESCQSGDGF------WCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKG  76
            D+C  V +   CQ+G          C C KGF    ++L   CID+DEC +        G
Sbjct  451  DYCQLVRYL--CQNGRCIPTPGSCRCECNKGFQ---LDLRGECIDVDECEKN----PCAG  501

Query  77   GDCVNIPGSFTCGCGPYRQE--KDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHK  134
            G+C+N  GS+TC C    Q       C DI+EC  N   C+ N  CIN DG    C C+ 
Sbjct  502  GECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICN-NGRCINTDGSFH-CVCNA  559

Query  135  GWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTED  194
            G+    D  N  C D++EC+   ++C  N +C N  GS+KC C  GF+  S G  C  +D
Sbjct  560  GFHVTRDGKN--CEDMDECSIR-NMC-LNGMCINEDGSFKCICKPGFQLASDGRYC--KD  613

Query  195  FCGTGKNDCDT----VFAACSLVPGSFKCECIQGF  225
                  N+C+T    +   C    GS++CEC  G 
Sbjct  614  I-----NECETPGICMNGRCVNTDGSYRCECFPGL  643


 Score = 74.3 bits (181),  Expect = 3e-13, Method: Compositional matrix adjust.
 Identities = 66/208 (31%), Positives = 93/208 (44%), Gaps = 16/208 (7%)

Query  29    EHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTC  88
             +H +   +   + C C  G+   G    + C+D DEC+ G + C    G C N+ G F C
Sbjct  2138  KHGQCINTDGSYRCECPFGYILAG----NECVDTDECSVG-NPCGN--GTCKNVIGGFEC  2190

Query  89    GCGP-YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVAC  147
              C   +       C DINEC+ N   C     C+N  G  + CKC  G+    D+    C
Sbjct  2191  TCEEGFEPGPMMTCEDINECAQNPLLCAFR--CVNTYGSYE-CKCPVGYVLREDR--RMC  2245

Query  148   RDINECNENPSICPSNSV-CTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTV  206
             +D +EC E    C    + C NL G+Y C C  G++    G GCV E+ C T    C+  
Sbjct  2246  KDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICEN-  2304

Query  207   FAACSLVPGSFKCECIQGFRGAGTVNTC  234
                C    GS+ CEC  GF  +   + C
Sbjct  2305  -GRCLNTRGSYTCECNDGFTASPNQDEC  2331


 Score = 73.6 bits (179),  Expect = 7e-13, Method: Compositional matrix adjust.
 Identities = 62/173 (35%), Positives = 83/173 (47%), Gaps = 24/173 (13%)

Query  60    IDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEKDGVCIDINECSTNRGNCDEN  117
             +DIDEC +    C+   G C+N+ GSF C C  G +  +K  VC DI+EC  N   C  N
Sbjct  1765  VDIDECREIPGVCEN--GVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRN  1821

Query  118   SDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCEC  177
             ++CIN  G  + C C  G+   +      C D NEC E P+IC S+  C +  GS+ C C
Sbjct  1822  AECINTAGSYR-CDCKPGYRFTSTG---QCNDRNECQEIPNIC-SHGQCIDTVGSFYCLC  1876

Query  178   SAGFEPDSSGSGCV-----TEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGF  225
               GF+ +   + C+       D CG G          C    GSF C C  GF
Sbjct  1877  HTGFKTNDDQTMCLDINECERDACGNG---------TCRNTIGSFNCRCNHGF  1920


 Score = 73.2 bits (178),  Expect = 8e-13, Method: Compositional matrix adjust.
 Identities = 62/165 (37%), Positives = 80/165 (48%), Gaps = 15/165 (9%)

Query  39    GFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQE  96
             GF C C++GF P  +    TC DI+ECAQ    C  +   CVN  GS+ C C  G   +E
Sbjct  2187  GFECTCEEGFEPGPM---MTCEDINECAQNPLLCAFR---CVNTYGSYECKCPVGYVLRE  2240

Query  97    KDGVCIDINECSTNRGNCDENS-DCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNE  155
                +C D +EC   + +C E   +C NL G   +C C  G+    D     C D NEC  
Sbjct  2241  DRRMCKDEDECEEGKHDCTEKQMECKNLIGT-YMCICGPGYQRRPD--GEGCVDENECQT  2297

Query  156   NPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCV--TEDFCGT  198
              P IC  N  C N  GSY CEC+ GF    +   C+   E +C T
Sbjct  2298  KPGIC-ENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFT  2341


 Score = 72.8 bits (177),  Expect = 1e-12, Method: Compositional matrix adjust.
 Identities = 80/231 (34%), Positives = 104/231 (45%), Gaps = 36/231 (15%)

Query  34   CQSGDG-FWCACQKGFTPQGINLSSTCIDIDEC-AQGLDNCKQKGGDCVNIPGSFTCGCG  91
            C + DG F C C+ GF  Q  +    C DI+EC   G+       G CVN  GS+ C C 
Sbjct  587  CINEDGSFKCICKPGF--QLASDGRYCKDINECETPGI----CMNGRCVNTDGSYRCECF  640

Query  92   P-YRQEKDG-VCIDINECST-----NRGNCDE-------NSDCINLDGEEQLCK-CHKGW  136
            P      DG VC+D +  ST      RG C +        S+C     E    + C    
Sbjct  641  PGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCP  700

Query  137  TGNNDKPNVACR----------DINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSS  186
              N+ +    C           DINEC  +P ICP N +C NL G+YKC C++G+E DS+
Sbjct  701  AQNSAEYQALCSSGPGMTSAGSDINECALDPDICP-NGICENLRGTYKCICNSGYEVDST  759

Query  187  GSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCEPL  237
            G  CV  + C      CD     C   PGSF C C +GF     + TCE +
Sbjct  760  GKNCVDINECVLNSLLCDN--GQCRNTPGSFVCTCPKGFIYKPDLKTCEDI  808


 Score = 70.5 bits (171),  Expect = 5e-12, Method: Compositional matrix adjust.
 Identities = 68/235 (28%), Positives = 97/235 (41%), Gaps = 50/235 (21%)

Query  34    CQSGDG-FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP  92
             C++ +G + C+C KG+  Q      +C D+DECA    NC+     CVN  G FTC C P
Sbjct  2459  CKNTEGSYQCSCPKGYILQ--EDGRSCKDLDECATKQHNCQFL---CVNTIGGFTCKCPP  2513

Query  93    YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINE  152
                +    CID NEC+++   C     C N  G    C+C +G++   D+   +C D++E
Sbjct  2514  GFTQHHTSCIDNNECTSDINLCGSKGICQNTPGS-FTCECQRGFS--LDQTGSSCEDVDE  2570

Query  153   CNENPSI--------------CPSNSV------------------------CTNLAGSYK  174
             C  N                 CP   +                        C N  GSYK
Sbjct  2571  CEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYK  2630

Query  175   CECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAG  229
             C C AGF+ +    GC   + CG+ +  C      CS   G + C C  G+   G
Sbjct  2631  CMCPAGFQYEQFSGGCQDINECGSAQAPCS---YGCSNTEGGYLCGCPPGYFRIG  2682


 Score = 68.9 bits (167),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 57/164 (34%), Positives = 78/164 (47%), Gaps = 11/164 (6%)

Query  75   KGGDCVNIPGSFTCGCGP-YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCH  133
            + G C+  PGS  C C   ++ +  G CID++EC  N        +CIN  G    C+C 
Sbjct  461  QNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPC---AGGECINNQGS-YTCQCR  516

Query  134  KGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTE  193
             G+     +    CRDI+EC +N  IC +N  C N  GS+ C C+AGF     G  C   
Sbjct  517  AGYQSTLTR--TECRDIDECLQNGRIC-NNGRCINTDGSFHCVCNAGFHVTRDGKNCEDM  573

Query  194  DFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCEPL  237
            D C   +N C  +   C    GSFKC C  GF+ A     C+ +
Sbjct  574  DECSI-RNMC--LNGMCINEDGSFKCICKPGFQLASDGRYCKDI  614


 Score = 67.0 bits (162),  Expect = 5e-11, Method: Compositional matrix adjust.
 Identities = 59/165 (35%), Positives = 85/165 (51%), Gaps = 15/165 (9%)

Query  29    EHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTC  88
             +HA+   +   + C C++G+T  G     TC D+DEC++ L+ C    G C+N PG + C
Sbjct  1376  QHADCKNTMGSYRCLCKEGYTGDGF----TCTDLDECSENLNLCGN--GQCLNAPGGYRC  1429

Query  89    GCGP-YRQEKDG-VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVA  146
              C   +    DG  C DI+ECS    N      C NL G  + C+C  G+    D+    
Sbjct  1430  ECDMGFVPSADGKACEDIDECSLP--NICVFGTCHNLPGLFR-CECEIGY--ELDRSGGN  1484

Query  147   CRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCV  191
             C D+NEC  +P+ C S + C N  GSY C+C   FE + +  GCV
Sbjct  1485  CTDVNEC-LDPTTCISGN-CVNTPGSYICDCPPDFELNPTRVGCV  1527


 Score = 61.2 bits (147),  Expect = 3e-09, Method: Compositional matrix adjust.
 Identities = 48/128 (37%), Positives = 66/128 (51%), Gaps = 8/128 (6%)

Query  99    GVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPS  158
             G+ +DI+EC    G C EN  CIN+ G  + C+C  G+  N+    + C DI+EC   P 
Sbjct  1762  GLPVDIDECREIPGVC-ENGVCINMVGSFR-CECPVGFFYNDKL--LVCEDIDECQNGP-  1816

Query  159   ICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFK  218
             +C  N+ C N AGSY+C+C  G+   S+G  C   + C    N C      C    GSF 
Sbjct  1817  VCQRNAECINTAGSYRCDCKPGYRFTSTGQ-CNDRNECQEIPNICS--HGQCIDTVGSFY  1873

Query  219   CECIQGFR  226
             C C  GF+
Sbjct  1874  CLCHTGFK  1881


 Score = 55.8 bits (133),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 64/203 (31%), Positives = 81/203 (39%), Gaps = 41/203 (20%)

Query  57    STCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEKDGVCIDIN---------  105
             + C DIDEC      CK   G CVN  GSF C C  G        +C+DI          
Sbjct  906   TQCEDIDECEVFPGVCKN--GLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYE  963

Query  106   --ECS---TNRGNCD---------------ENSDCINLDGEEQLCKCHKGWTGN---NDK  142
               EC+     R   D               E     N    E+LC    G+      N K
Sbjct  964   DEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGK  1023

Query  143   PNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKND  202
             P    +DINEC   PS+C ++  C N  GS+KC C +GF  DS    C   D C    + 
Sbjct  1024  PFF--KDINECKMIPSLC-THGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDL  1080

Query  203   CDTVFAACSLVPGSFKCECIQGF  225
             C      C   PG F+C+C +G+
Sbjct  1081  CGR--GQCVNTPGDFECKCDEGY  1101


 Score = 47.8 bits (112),  Expect = 3e-05, Method: Compositional matrix adjust.
 Identities = 53/174 (30%), Positives = 69/174 (39%), Gaps = 32/174 (18%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYR--QEK  97
            F C C KGF  +      TC DIDEC           G C N PGSF C C         
Sbjct  788  FVCTCPKGFIYKPD--LKTCEDIDECESS----PCINGVCKNSPGSFICECSSESTLDPT  841

Query  98   DGVCIDI-----------NECSTNRGNCDENSDCINLDGEE-----QLCK----CHKGWT  137
              +CI+              C  N       S C +  G        LC+    C KG++
Sbjct  842  KTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYS  901

Query  138  GNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCV  191
                     C DI+EC   P +C  N +C N  GS+KC+C +G   D++G  C+
Sbjct  902  ---RIKGTQCEDIDECEVFPGVC-KNGLCVNTRGSFKCQCPSGMTLDATGRICL  951


 Score = 47.8 bits (112),  Expect = 4e-05, Method: Compositional matrix adjust.
 Identities = 35/95 (36%), Positives = 48/95 (50%), Gaps = 5/95 (5%)

Query  97   KDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNEN  156
            + G C D++EC    G C +  +CIN  G  + CKC  G   N  + +  C DI+EC+  
Sbjct  240  RTGACQDVDECQAIPGLC-QGGNCINTVGSFE-CKCPAGHKLN--EVSQKCEDIDECSTI  295

Query  157  PSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCV  191
            P IC     CTN   SY C+C  GF     G+ C+
Sbjct  296  PGICEGGE-CTNTVSSYFCKCPPGFYTSPDGTRCI  329


 Score = 41.2 bits (95),  Expect = 0.003, Method: Compositional matrix adjust.
 Identities = 29/66 (43%), Positives = 35/66 (53%), Gaps = 6/66 (9%)

Query  46    KGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEKDGVCID  103
             +GF P  I +     DIDEC +    C+  GG C+N  GSF C C  G Y  E   VC D
Sbjct  1593  EGFRPNPITVILE--DIDECQELPGLCQ--GGKCINTFGSFQCRCPTGYYLNEDTRVCDD  1648

Query  104   INECST  109
             +NEC T
Sbjct  1649  VNECET  1654


 Score = 41.2 bits (95),  Expect = 0.004, Method: Compositional matrix adjust.
 Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 11/97 (11%)

Query  132  CHKGWTGNNDKPNV---ACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGS  188
            C +G+      PN+   AC+D++EC   P +C   + C N  GS++C+C AG + +    
Sbjct  231  CRRGFI-----PNIRTGACQDVDECQAIPGLCQGGN-CINTVGSFECKCPAGHKLNEVSQ  284

Query  189  GCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGF  225
             C   D C T    C+     C+    S+ C+C  GF
Sbjct  285  KCEDIDECSTIPGICEG--GECTNTVSSYFCKCPPGF  319


 Score = 40.4 bits (93),  Expect = 0.006, Method: Compositional matrix adjust.
 Identities = 33/89 (37%), Positives = 43/89 (48%), Gaps = 6/89 (6%)

Query  103   DINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPS  162
             DI+EC    G C +   CIN  G  Q C+C  G+  N D     C D+NEC E P IC  
Sbjct  1606  DIDECQELPGLC-QGGKCINTFGSFQ-CRCPTGYYLNED--TRVCDDVNEC-ETPGIC-G  1659

Query  163   NSVCTNLAGSYKCECSAGFEPDSSGSGCV  191
                C N  G+Y C C   +   + G+ C+
Sbjct  1660  PGTCYNTVGNYTCICPPDYMQVNGGNNCM  1688


 Score = 38.9 bits (89),  Expect = 0.014, Method: Compositional matrix adjust.
 Identities = 47/176 (26%), Positives = 64/176 (36%), Gaps = 40/176 (22%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQ----  95
             F C C+ G+          C D++EC   LD      G+CVN PGS+ C C P  +    
Sbjct  1468  FRCECEIGYELD--RSGGNCTDVNEC---LDPTTCISGNCVNTPGSYICDCPPDFELNPT  1522

Query  96    ------EKDGVC-IDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWT-----------  137
                    + G C +DI     N      N   + +      C   K W            
Sbjct  1523  RVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNT  1582

Query  138   ---------GNNDKPN---VACRDINECNENPSICPSNSVCTNLAGSYKCECSAGF  181
                      G   +PN   V   DI+EC E P +C     C N  GS++C C  G+
Sbjct  1583  SEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGK-CINTFGSFQCRCPTGY  1637


 Score = 38.9 bits (89),  Expect = 0.016, Method: Compositional matrix adjust.
 Identities = 73/273 (26%), Positives = 102/273 (37%), Gaps = 70/273 (25%)

Query  25   CSRVEHA--ESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNI  82
            C+  E+A  E CQ       A  +     G  ++S   DI+ECA   D C    G C N+
Sbjct  685  CASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPN--GICENL  742

Query  83   PGSFTCGCGP-YRQEKDGV-CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNN  140
             G++ C C   Y  +  G  C+DINEC  N   CD N  C N  G   +C C KG+    
Sbjct  743  RGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCD-NGQCRNTPGS-FVCTCPKGFI---  797

Query  141  DKPNV-ACRDINECNENPSIC---------------------PSNSVCT-----------  167
             KP++  C DI+EC  +P I                      P+ ++C            
Sbjct  798  YKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTV  857

Query  168  -------NLAGSY---KCECSAGFEPDSSGSGCVTEDFCGTGK-----------NDCDTV  206
                   N+ G+    +C  S G    S  + C  +  CG G            ++C+  
Sbjct  858  IDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVF  917

Query  207  FAACSL-----VPGSFKCECIQGFRGAGTVNTC  234
               C         GSFKC+C  G     T   C
Sbjct  918  PGVCKNGLCVNTRGSFKCQCPSGMTLDATGRIC  950


> Hs4557591
Length=2871

 Score =  100 bits (250),  Expect = 3e-21, Method: Compositional matrix adjust.
 Identities = 71/186 (38%), Positives = 94/186 (50%), Gaps = 12/186 (6%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDG  99
             F C C  G++  G    + C DI+EC  G  NC  K   C N  GSF C C P       
Sbjct  1303  FICHCDMGYS--GKKGKTGCTDINECEIGAHNCG-KHAVCTNTAGSFKCSCSPGWIGDGI  1359

Query  100   VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSI  159
              C D++ECS     C +++DC N  G  + C C +G+TG+       C D++EC+EN ++
Sbjct  1360  KCTDLDECSNGTHMCSQHADCKNTMGSYR-CLCKEGYTGDG----FTCTDLDECSENLNL  1414

Query  160   CPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKC  219
             C  N  C N  G Y+CEC  GF P + G  C   D C    N C  VF  C  +PG F+C
Sbjct  1415  C-GNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSL-PNIC--VFGTCHNLPGLFRC  1470

Query  220   ECIQGF  225
             EC  G+
Sbjct  1471  ECEIGY  1476


 Score = 94.7 bits (234),  Expect = 3e-19, Method: Compositional matrix adjust.
 Identities = 73/192 (38%), Positives = 95/192 (49%), Gaps = 13/192 (6%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEK  97
             + C+CQ GF    +    +C DIDEC    + C   GG C NIPG + C C  G    E 
Sbjct  1219  YECSCQPGFAL--MPDQRSCTDIDECEDNPNICD--GGQCTNIPGEYRCLCYDGFMASED  1274

Query  98    DGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP  157
                C+D+NEC  N   C   + C N  G   +C C  G++G   K    C DINEC    
Sbjct  1275  MKTCVDVNECDLNPNICLSGT-CENTKGS-FICHCDMGYSGKKGK--TGCTDINECEIGA  1330

Query  158   SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSF  217
               C  ++VCTN AGS+KC CS G+  D  G  C   D C  G + C +  A C    GS+
Sbjct  1331  HNCGKHAVCTNTAGSFKCSCSPGWIGD--GIKCTDLDECSNGTHMC-SQHADCKNTMGSY  1387

Query  218   KCECIQGFRGAG  229
             +C C +G+ G G
Sbjct  1388  RCLCKEGYTGDG  1399


 Score = 87.0 bits (214),  Expect = 5e-17, Method: Compositional matrix adjust.
 Identities = 68/197 (34%), Positives = 95/197 (48%), Gaps = 18/197 (9%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEK  97
             + C C+ G+TP     S  C+D++EC Q    C      C N  GS+ C C  G   QE 
Sbjct  2425  YHCICKTGYTPDITGTS--CVDLNECNQAPKPCNFI---CKNTEGSYQCSCPKGYILQED  2479

Query  98    DGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP  157
                C D++EC+T + NC     C+N  G    CKC  G+T    + + +C D NEC  + 
Sbjct  2480  GRSCKDLDECATKQHNC--QFLCVNTIGG-FTCKCPPGFT----QHHTSCIDNNECTSDI  2532

Query  158   SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSF  217
             ++C S  +C N  GS+ CEC  GF  D +GS C   D C  G + C      C  + G +
Sbjct  2533  NLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDEC-EGNHRCQ---HGCQNIIGGY  2588

Query  218   KCECIQGFRGAGTVNTC  234
             +C C QG+      N C
Sbjct  2589  RCSCPQGYLQHYQWNQC  2605


 Score = 84.3 bits (207),  Expect = 3e-16, Method: Compositional matrix adjust.
 Identities = 64/153 (41%), Positives = 81/153 (52%), Gaps = 13/153 (8%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
             F C C  GF    ++ ++ CID+DECA G  N   + G C+N  GSF C C   Y    D
Sbjct  1912  FNCRCNHGFI---LSHNNDCIDVDECASGNGN-LCRNGQCINTVGSFQCQCNEGYEVAPD  1967

Query  99    G-VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP  157
             G  C+DINEC      C   + C NLDG  + C C  G++  N+K    C DI+EC E P
Sbjct  1968  GRTCVDINECLLEPRKCAPGT-CQNLDGSYR-CICPPGYSLQNEK----CEDIDECVEEP  2021

Query  158   SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGC  190
              IC +   C+N  GS+KC C  GF   SSG  C
Sbjct  2022  EIC-ALGTCSNTEGSFKCLCPEGFSLSSSGRRC  2053


 Score = 82.4 bits (202),  Expect = 1e-15, Method: Compositional matrix adjust.
 Identities = 68/197 (34%), Positives = 94/197 (47%), Gaps = 14/197 (7%)

Query  29    EHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTC  88
             +HA    +   F C+C  G+   GI     C D+DEC+ G   C Q   DC N  GS+ C
Sbjct  1335  KHAVCTNTAGSFKCSCSPGWIGDGIK----CTDLDECSNGTHMCSQH-ADCKNTMGSYRC  1389

Query  89    GCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACR  148
              C          C D++ECS N   C  N  C+N  G  + C+C  G+  + D    AC 
Sbjct  1390  LCKEGYTGDGFTCTDLDECSENLNLCG-NGQCLNAPGGYR-CECDMGFVPSAD--GKACE  1445

Query  149   DINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFA  208
             DI+EC+  P+IC   + C NL G ++CEC  G+E D SG  C   + C    +    +  
Sbjct  1446  DIDECSL-PNICVFGT-CHNLPGLFRCECEIGYELDRSGGNCTDVNEC---LDPTTCISG  1500

Query  209   ACSLVPGSFKCECIQGF  225
              C   PGS+ C+C   F
Sbjct  1501  NCVNTPGSYICDCPPDF  1517


 Score = 79.3 bits (194),  Expect = 1e-14, Method: Compositional matrix adjust.
 Identities = 66/186 (35%), Positives = 90/186 (48%), Gaps = 17/186 (9%)

Query  60    IDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDGVCIDINECSTNRGNCDENSD  119
             +D+DEC +  D CK   G C+N  GS+ C C          C+D +ECS   GN   N  
Sbjct  2126  VDMDECKE-PDVCKH--GQCINTDGSYRCECPFGYTLAGNECVDTDECSV--GNPCGNGT  2180

Query  120   CINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSA  179
             C N+ G  + C C +G+      P + C DINEC +NP +C     C N  GSY+C+C  
Sbjct  2181  CKNVIGGFE-CTCEEGF---EPGPMMTCEDINECAQNPLLCAFR--CVNTYGSYECKCPV  2234

Query  180   GFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFR----GAGTV--NT  233
             G+        C  ED C  GK+DC      C  + G++ C C  G++    G G V  N 
Sbjct  2235  GYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENE  2294

Query  234   CEPLPG  239
             C+  PG
Sbjct  2295  CQTKPG  2300


 Score = 78.2 bits (191),  Expect = 2e-14, Method: Compositional matrix adjust.
 Identities = 75/215 (34%), Positives = 104/215 (48%), Gaps = 34/215 (15%)

Query  23   DHCSRVEHAESCQSGD------GFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKG  76
            D+C  V +   CQ+G        + C C KGF    ++L   CID+DEC +        G
Sbjct  451  DYCQLVRYL--CQNGRCIPTPGSYRCECNKGFQ---LDLRGECIDVDECEKN----PCAG  501

Query  77   GDCVNIPGSFTCGCGPYRQE--KDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHK  134
            G+C+N  GS+TC C    Q       C DI+EC  N   C+ N  CIN DG    C C+ 
Sbjct  502  GECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICN-NGRCINTDGSFH-CVCNA  559

Query  135  GWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTED  194
            G+    D  N  C D++EC+   ++C  N +C N  GS+KC C  GF+  S G  C  +D
Sbjct  560  GFHVTRDGKN--CEDMDECSIR-NMC-LNGMCINEDGSFKCICKPGFQLASDGRYC--KD  613

Query  195  FCGTGKNDCDT----VFAACSLVPGSFKCECIQGF  225
                  N+C+T    +   C    GS++CEC  G 
Sbjct  614  I-----NECETPGICMNGRCVNTDGSYRCECFPGL  643


 Score = 77.8 bits (190),  Expect = 3e-14, Method: Compositional matrix adjust.
 Identities = 71/197 (36%), Positives = 90/197 (45%), Gaps = 16/197 (8%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
             F C C  GF      L   C DIDEC  G     Q+  +C+N  GS+ C C P YR    
Sbjct  1789  FRCECPVGFFYNDKLL--VCEDIDECQNGP--VCQRNAECINTAGSYRCDCKPGYRFTST  1844

Query  99    GVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPS  158
             G C D NEC      C  +  CI+  G    C CH G+  N+D+    C DINEC  +  
Sbjct  1845  GQCNDRNECQEIPNIC-SHGQCIDTVG-SFYCLCHTGFKTNDDQ--TMCLDINECERDAC  1900

Query  159   ICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGK-NDCDTVFAACSLVPGSF  217
                 N  C N  GS+ C C+ GF   S  + C+  D C +G  N C      C    GSF
Sbjct  1901  ---GNGTCRNTIGSFNCRCNHGFIL-SHNNDCIDVDECASGNGNLCRN--GQCINTVGSF  1954

Query  218   KCECIQGFRGAGTVNTC  234
             +C+C +G+  A    TC
Sbjct  1955  QCQCNEGYEVAPDGRTC  1971


 Score = 77.4 bits (189),  Expect = 4e-14, Method: Compositional matrix adjust.
 Identities = 81/273 (29%), Positives = 117/273 (42%), Gaps = 20/273 (7%)

Query  46    KGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKDGV-CID  103
             K   P G    +   DIDEC    D C+   G+CVN  GS+ C C   Y  +  G  C+D
Sbjct  2387  KKLCPHGRGFMTNGADIDECKVIHDVCRN--GECVNDRGSYHCICKTGYTPDITGTSCVD  2444

Query  104   INECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSN  163
             +NEC+     C  N  C N +G  Q C C KG+    D    +C+D++EC      C   
Sbjct  2445  LNECNQAPKPC--NFICKNTEGSYQ-CSCPKGYILQED--GRSCKDLDECATKQHNC--Q  2497

Query  164   SVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQ  223
              +C N  G + C+C  GF      + C+  + C +  N C +    C   PGSF CEC +
Sbjct  2498  FLCVNTIGGFTCKCPPGFT--QHHTSCIDNNECTSDINLCGSK-GICQNTPGSFTCECQR  2554

Query  224   GFRGAGTVNTCEPL---PGNEDLACTTLGLTCGDYKYCTKSTTQAGLW-ECTDKAASEQL  279
             GF    T ++CE +    GN         +  G    C +   Q   W +C D+  +E L
Sbjct  2555  GFSLDQTGSSCEDVDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDE--NECL  2612

Query  280   AVFIANGATSDTPSWVWAVVVLSTIALILISGG  312
             +  I  GA+       +  +  +       SGG
Sbjct  2613  SAHICGGASCHNTLGSYKCMCPAGFQYEQFSGG  2645


 Score = 77.0 bits (188),  Expect = 5e-14, Method: Compositional matrix adjust.
 Identities = 72/211 (34%), Positives = 95/211 (45%), Gaps = 27/211 (12%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-----YR  94
             F C C  GF     +    C DIDEC    D C +  G CVN PG F C C       + 
Sbjct  1051  FKCRCDSGFALD--SEERNCTDIDECRISPDLCGR--GQCVNTPGDFECKCDEGYESGFM  1106

Query  95    QEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNV-ACRDINEC  153
               K+  C+DI+EC  +   C     C N +G  + C+C  G   +   PN+ AC DINEC
Sbjct  1107  MMKN--CMDIDECQRDPLLC-RGGVCHNTEGSYR-CECPPG---HQLSPNISACIDINEC  1159

Query  154   NENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLV  213
               +  +CP N  C NL G Y+C C+ G+        CV  D C      C+T    C+  
Sbjct  1160  ELSAHLCP-NGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETF---CTNS  1215

Query  214   PGSFKCECIQGF------RGAGTVNTCEPLP  238
              GS++C C  GF      R    ++ CE  P
Sbjct  1216  EGSYECSCQPGFALMPDQRSCTDIDECEDNP  1246


 Score = 76.3 bits (186),  Expect = 1e-13, Method: Compositional matrix adjust.
 Identities = 67/208 (32%), Positives = 94/208 (45%), Gaps = 16/208 (7%)

Query  29    EHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTC  88
             +H +   +   + C C  G+T  G    + C+D DEC+ G + C    G C N+ G F C
Sbjct  2138  KHGQCINTDGSYRCECPFGYTLAG----NECVDTDECSVG-NPCGN--GTCKNVIGGFEC  2190

Query  89    GCGP-YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVAC  147
              C   +       C DINEC+ N   C     C+N  G  + CKC  G+    D+    C
Sbjct  2191  TCEEGFEPGPMMTCEDINECAQNPLLCAFR--CVNTYGSYE-CKCPVGYVLREDR--RMC  2245

Query  148   RDINECNENPSICPSNSV-CTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTV  206
             +D +EC E    C    + C NL G+Y C C  G++    G GCV E+ C T    C+  
Sbjct  2246  KDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICEN-  2304

Query  207   FAACSLVPGSFKCECIQGFRGAGTVNTC  234
                C    GS+ CEC  GF  +   + C
Sbjct  2305  -GRCLNTRGSYTCECNDGFTASPNQDEC  2331


 Score = 73.2 bits (178),  Expect = 7e-13, Method: Compositional matrix adjust.
 Identities = 62/173 (35%), Positives = 83/173 (47%), Gaps = 24/173 (13%)

Query  60    IDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEKDGVCIDINECSTNRGNCDEN  117
             +DIDEC +    C+   G C+N+ GSF C C  G +  +K  VC DI+EC  N   C  N
Sbjct  1765  VDIDECREIPGVCEN--GVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRN  1821

Query  118   SDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCEC  177
             ++CIN  G  + C C  G+   +      C D NEC E P+IC S+  C +  GS+ C C
Sbjct  1822  AECINTAGSYR-CDCKPGYRFTSTG---QCNDRNECQEIPNIC-SHGQCIDTVGSFYCLC  1876

Query  178   SAGFEPDSSGSGCV-----TEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGF  225
               GF+ +   + C+       D CG G          C    GSF C C  GF
Sbjct  1877  HTGFKTNDDQTMCLDINECERDACGNG---------TCRNTIGSFNCRCNHGF  1920


 Score = 73.2 bits (178),  Expect = 9e-13, Method: Compositional matrix adjust.
 Identities = 62/165 (37%), Positives = 80/165 (48%), Gaps = 15/165 (9%)

Query  39    GFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQE  96
             GF C C++GF P  +    TC DI+ECAQ    C  +   CVN  GS+ C C  G   +E
Sbjct  2187  GFECTCEEGFEPGPM---MTCEDINECAQNPLLCAFR---CVNTYGSYECKCPVGYVLRE  2240

Query  97    KDGVCIDINECSTNRGNCDENS-DCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNE  155
                +C D +EC   + +C E   +C NL G   +C C  G+    D     C D NEC  
Sbjct  2241  DRRMCKDEDECEEGKHDCTEKQMECKNLIGT-YMCICGPGYQRRPD--GEGCVDENECQT  2297

Query  156   NPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCV--TEDFCGT  198
              P IC  N  C N  GSY CEC+ GF    +   C+   E +C T
Sbjct  2298  KPGIC-ENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFT  2341


 Score = 72.8 bits (177),  Expect = 1e-12, Method: Compositional matrix adjust.
 Identities = 80/231 (34%), Positives = 104/231 (45%), Gaps = 36/231 (15%)

Query  34   CQSGDG-FWCACQKGFTPQGINLSSTCIDIDEC-AQGLDNCKQKGGDCVNIPGSFTCGCG  91
            C + DG F C C+ GF  Q  +    C DI+EC   G+       G CVN  GS+ C C 
Sbjct  587  CINEDGSFKCICKPGF--QLASDGRYCKDINECETPGI----CMNGRCVNTDGSYRCECF  640

Query  92   P-YRQEKDG-VCIDINECST-----NRGNCDE-------NSDCINLDGEEQLCK-CHKGW  136
            P      DG VC+D +  ST      RG C +        S+C     E    + C    
Sbjct  641  PGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCP  700

Query  137  TGNNDKPNVACR----------DINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSS  186
              N+ +    C           DINEC  +P ICP N +C NL G+YKC C++G+E DS+
Sbjct  701  AQNSAEYQALCSSGPGMTSAGSDINECALDPDICP-NGICENLRGTYKCICNSGYEVDST  759

Query  187  GSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCEPL  237
            G  CV  + C      CD     C   PGSF C C +GF     + TCE +
Sbjct  760  GKNCVDINECVLNSLLCDN--GQCRNTPGSFVCTCPKGFIYKPDLKTCEDI  808


 Score = 71.6 bits (174),  Expect = 2e-12, Method: Compositional matrix adjust.
 Identities = 57/164 (34%), Positives = 79/164 (48%), Gaps = 11/164 (6%)

Query  75   KGGDCVNIPGSFTCGCGP-YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCH  133
            + G C+  PGS+ C C   ++ +  G CID++EC  N        +CIN  G    C+C 
Sbjct  461  QNGRCIPTPGSYRCECNKGFQLDLRGECIDVDECEKNPC---AGGECINNQGS-YTCQCR  516

Query  134  KGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTE  193
             G+     +    CRDI+EC +N  IC +N  C N  GS+ C C+AGF     G  C   
Sbjct  517  AGYQSTLTR--TECRDIDECLQNGRIC-NNGRCINTDGSFHCVCNAGFHVTRDGKNCEDM  573

Query  194  DFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCEPL  237
            D C   +N C  +   C    GSFKC C  GF+ A     C+ +
Sbjct  574  DECSI-RNMC--LNGMCINEDGSFKCICKPGFQLASDGRYCKDI  614


 Score = 70.5 bits (171),  Expect = 5e-12, Method: Compositional matrix adjust.
 Identities = 69/235 (29%), Positives = 97/235 (41%), Gaps = 50/235 (21%)

Query  34    CQSGDG-FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP  92
             C++ +G + C+C KG+  Q    S  C D+DECA    NC+     CVN  G FTC C P
Sbjct  2459  CKNTEGSYQCSCPKGYILQEDGRS--CKDLDECATKQHNCQFL---CVNTIGGFTCKCPP  2513

Query  93    YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINE  152
                +    CID NEC+++   C     C N  G    C+C +G++   D+   +C D++E
Sbjct  2514  GFTQHHTSCIDNNECTSDINLCGSKGICQNTPGS-FTCECQRGFS--LDQTGSSCEDVDE  2570

Query  153   CNENPSI--------------CPSNSV------------------------CTNLAGSYK  174
             C  N                 CP   +                        C N  GSYK
Sbjct  2571  CEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYK  2630

Query  175   CECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAG  229
             C C AGF+ +    GC   + CG+ +  C      CS   G + C C  G+   G
Sbjct  2631  CMCPAGFQYEQFSGGCQDINECGSAQAPCS---YGCSNTEGGYLCGCPPGYFRIG  2682


 Score = 67.0 bits (162),  Expect = 5e-11, Method: Compositional matrix adjust.
 Identities = 59/165 (35%), Positives = 85/165 (51%), Gaps = 15/165 (9%)

Query  29    EHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTC  88
             +HA+   +   + C C++G+T  G     TC D+DEC++ L+ C    G C+N PG + C
Sbjct  1376  QHADCKNTMGSYRCLCKEGYTGDGF----TCTDLDECSENLNLCGN--GQCLNAPGGYRC  1429

Query  89    GCGP-YRQEKDG-VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVA  146
              C   +    DG  C DI+ECS    N      C NL G  + C+C  G+    D+    
Sbjct  1430  ECDMGFVPSADGKACEDIDECSLP--NICVFGTCHNLPGLFR-CECEIGY--ELDRSGGN  1484

Query  147   CRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCV  191
             C D+NEC  +P+ C S + C N  GSY C+C   FE + +  GCV
Sbjct  1485  CTDVNEC-LDPTTCISGN-CVNTPGSYICDCPPDFELNPTRVGCV  1527


 Score = 61.2 bits (147),  Expect = 3e-09, Method: Compositional matrix adjust.
 Identities = 48/128 (37%), Positives = 66/128 (51%), Gaps = 8/128 (6%)

Query  99    GVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPS  158
             G+ +DI+EC    G C EN  CIN+ G  + C+C  G+  N+    + C DI+EC   P 
Sbjct  1762  GLPVDIDECREIPGVC-ENGVCINMVGSFR-CECPVGFFYNDKL--LVCEDIDECQNGP-  1816

Query  159   ICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFK  218
             +C  N+ C N AGSY+C+C  G+   S+G  C   + C    N C      C    GSF 
Sbjct  1817  VCQRNAECINTAGSYRCDCKPGYRFTSTGQ-CNDRNECQEIPNICS--HGQCIDTVGSFY  1873

Query  219   CECIQGFR  226
             C C  GF+
Sbjct  1874  CLCHTGFK  1881


 Score = 55.8 bits (133),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 64/203 (31%), Positives = 81/203 (39%), Gaps = 41/203 (20%)

Query  57    STCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEKDGVCIDIN---------  105
             + C DIDEC      CK   G CVN  GSF C C  G        +C+DI          
Sbjct  906   TQCEDIDECEVFPGVCKN--GLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYE  963

Query  106   --ECS---TNRGNCD---------------ENSDCINLDGEEQLCKCHKGWTGN---NDK  142
               EC+     R   D               E     N    E+LC    G+      N K
Sbjct  964   DEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGK  1023

Query  143   PNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKND  202
             P    +DINEC   PS+C ++  C N  GS+KC C +GF  DS    C   D C    + 
Sbjct  1024  PFF--KDINECKMIPSLC-THGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDL  1080

Query  203   CDTVFAACSLVPGSFKCECIQGF  225
             C      C   PG F+C+C +G+
Sbjct  1081  CGR--GQCVNTPGDFECKCDEGY  1101


 Score = 47.8 bits (112),  Expect = 3e-05, Method: Compositional matrix adjust.
 Identities = 53/174 (30%), Positives = 69/174 (39%), Gaps = 32/174 (18%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYR--QEK  97
            F C C KGF  +      TC DIDEC           G C N PGSF C C         
Sbjct  788  FVCTCPKGFIYKPD--LKTCEDIDECESS----PCINGVCKNSPGSFICECSSESTLDPT  841

Query  98   DGVCIDI-----------NECSTNRGNCDENSDCINLDGEE-----QLCK----CHKGWT  137
              +CI+              C  N       S C +  G        LC+    C KG++
Sbjct  842  KTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYS  901

Query  138  GNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCV  191
                     C DI+EC   P +C  N +C N  GS+KC+C +G   D++G  C+
Sbjct  902  ---RIKGTQCEDIDECEVFPGVC-KNGLCVNTRGSFKCQCPSGMTLDATGRICL  951


 Score = 47.8 bits (112),  Expect = 4e-05, Method: Compositional matrix adjust.
 Identities = 35/95 (36%), Positives = 48/95 (50%), Gaps = 5/95 (5%)

Query  97   KDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNEN  156
            + G C D++EC    G C +  +CIN  G  + CKC  G   N  + +  C DI+EC+  
Sbjct  240  RTGACQDVDECQAIPGLC-QGGNCINTVGSFE-CKCPAGHKLN--EVSQKCEDIDECSTI  295

Query  157  PSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCV  191
            P IC     CTN   SY C+C  GF     G+ C+
Sbjct  296  PGICEGGE-CTNTVSSYFCKCPPGFYTSPDGTRCI  329


 Score = 41.2 bits (95),  Expect = 0.003, Method: Compositional matrix adjust.
 Identities = 29/66 (43%), Positives = 35/66 (53%), Gaps = 6/66 (9%)

Query  46    KGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEKDGVCID  103
             +GF P  I +     DIDEC +    C+  GG C+N  GSF C C  G Y  E   VC D
Sbjct  1593  EGFRPNPITVILE--DIDECQELPGLCQ--GGKCINTFGSFQCRCPTGYYLNEDTRVCDD  1648

Query  104   INECST  109
             +NEC T
Sbjct  1649  VNECET  1654


 Score = 41.2 bits (95),  Expect = 0.004, Method: Compositional matrix adjust.
 Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 11/97 (11%)

Query  132  CHKGWTGNNDKPNV---ACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGS  188
            C +G+      PN+   AC+D++EC   P +C   + C N  GS++C+C AG + +    
Sbjct  231  CRRGFI-----PNIRTGACQDVDECQAIPGLCQGGN-CINTVGSFECKCPAGHKLNEVSQ  284

Query  189  GCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGF  225
             C   D C T    C+     C+    S+ C+C  GF
Sbjct  285  KCEDIDECSTIPGICEG--GECTNTVSSYFCKCPPGF  319


 Score = 40.4 bits (93),  Expect = 0.006, Method: Compositional matrix adjust.
 Identities = 33/89 (37%), Positives = 43/89 (48%), Gaps = 6/89 (6%)

Query  103   DINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPS  162
             DI+EC    G C +   CIN  G  Q C+C  G+  N D     C D+NEC E P IC  
Sbjct  1606  DIDECQELPGLC-QGGKCINTFGSFQ-CRCPTGYYLNED--TRVCDDVNEC-ETPGIC-G  1659

Query  163   NSVCTNLAGSYKCECSAGFEPDSSGSGCV  191
                C N  G+Y C C   +   + G+ C+
Sbjct  1660  PGTCYNTVGNYTCICPPDYMQVNGGNNCM  1688


 Score = 38.9 bits (89),  Expect = 0.014, Method: Compositional matrix adjust.
 Identities = 47/176 (26%), Positives = 64/176 (36%), Gaps = 40/176 (22%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQ----  95
             F C C+ G+          C D++EC   LD      G+CVN PGS+ C C P  +    
Sbjct  1468  FRCECEIGYELD--RSGGNCTDVNEC---LDPTTCISGNCVNTPGSYICDCPPDFELNPT  1522

Query  96    ------EKDGVC-IDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWT-----------  137
                    + G C +DI     N      N   + +      C   K W            
Sbjct  1523  RVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNT  1582

Query  138   ---------GNNDKPN---VACRDINECNENPSICPSNSVCTNLAGSYKCECSAGF  181
                      G   +PN   V   DI+EC E P +C     C N  GS++C C  G+
Sbjct  1583  SEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGK-CINTFGSFQCRCPTGY  1637


 Score = 38.9 bits (89),  Expect = 0.017, Method: Compositional matrix adjust.
 Identities = 73/273 (26%), Positives = 102/273 (37%), Gaps = 70/273 (25%)

Query  25   CSRVEHA--ESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNI  82
            C+  E+A  E CQ       A  +     G  ++S   DI+ECA   D C    G C N+
Sbjct  685  CASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPN--GICENL  742

Query  83   PGSFTCGCGP-YRQEKDGV-CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNN  140
             G++ C C   Y  +  G  C+DINEC  N   CD N  C N  G   +C C KG+    
Sbjct  743  RGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCD-NGQCRNTPGS-FVCTCPKGFI---  797

Query  141  DKPNV-ACRDINECNENPSIC---------------------PSNSVCT-----------  167
             KP++  C DI+EC  +P I                      P+ ++C            
Sbjct  798  YKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTV  857

Query  168  -------NLAGSY---KCECSAGFEPDSSGSGCVTEDFCGTGK-----------NDCDTV  206
                   N+ G+    +C  S G    S  + C  +  CG G            ++C+  
Sbjct  858  IDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVF  917

Query  207  FAACSL-----VPGSFKCECIQGFRGAGTVNTC  234
               C         GSFKC+C  G     T   C
Sbjct  918  PGVCKNGLCVNTRGSFKCQCPSGMTLDATGRIC  950


> Hs5453766
Length=816

 Score = 95.5 bits (236),  Expect = 1e-19, Method: Compositional matrix adjust.
 Identities = 82/243 (33%), Positives = 111/243 (45%), Gaps = 45/243 (18%)

Query  21   GYDHCSR----VEHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKG  76
            GYD CS     +E++      D   C+C+ GF     + ++ C DIDECA+G   C++  
Sbjct  397  GYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALRED-NAYCEDIDECAEGRHYCRENT  455

Query  77   GDCVNIPGSFTCGCGP-YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKG  135
              CVN PGSF C C   Y +  D  C + +EC TN+ NCDEN+ C N  G    C C  G
Sbjct  456  M-CVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHN-CVCKPG  513

Query  136  WTGNNDKPNVACRD----------------------------INECNENPSICPSNSVCT  167
            +TGN       C+D                            I+EC++    C S + C 
Sbjct  514  YTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCI  573

Query  168  NLAGSYKCECSAGFEPD----SSGSGCVTEDFCGTGKNDC--DTVFAACSLVPGSFKCEC  221
            NL G Y CEC  G+  +     SG  C   D CGTG++ C  DT+   C  + G + C C
Sbjct  574  NLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTI---CFNLDGGYDCRC  630

Query  222  IQG  224
              G
Sbjct  631  PHG  633


 Score = 63.5 bits (153),  Expect = 6e-10, Method: Compositional matrix adjust.
 Identities = 48/132 (36%), Positives = 63/132 (47%), Gaps = 5/132 (3%)

Query  100  VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSI  159
            VC   + CS  R NC ENS C NL+ +  +C C  G+    +  N  C DI+EC E    
Sbjct  394  VCKGYDFCS-ERHNCMENSICRNLN-DRAVCSCRDGFRALRED-NAYCEDIDECAEGRHY  450

Query  160  CPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKC  219
            C  N++C N  GS+ C C  G+      S C   D C T +++CD   A C    G   C
Sbjct  451  CRENTMCVNTPGSFMCICKTGYIRIDDYS-CTEHDECITNQHNCDEN-ALCFNTVGGHNC  508

Query  220  ECIQGFRGAGTV  231
             C  G+ G GT 
Sbjct  509  VCKPGYTGNGTT  520


 Score = 58.2 bits (139),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 56/219 (25%), Positives = 89/219 (40%), Gaps = 44/219 (20%)

Query  51   QGINLSSTCIDIDECAQGLDNCKQK-----GGDCVNIPGSFTCGCGP-YR--QEKDGVCI  102
              I LS +C  +    +G D C ++        C N+     C C   +R  +E +  C 
Sbjct  383  HQITLSHSCCKV---CKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCE  439

Query  103  DINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPS  162
            DI+EC+  R  C EN+ C+N  G   +C C  G+   +D    +C + +EC  N   C  
Sbjct  440  DIDECAEGRHYCRENTMCVNTPGSF-MCICKTGYIRIDD---YSCTEHDECITNQHNCDE  495

Query  163  NSVCTNLAGSYKCECSAGFEPD------------SSGSGCVTEDFCG-----------TG  199
            N++C N  G + C C  G+  +             +G  C+  + C            T 
Sbjct  496  NALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETD  555

Query  200  KNDCDTVF------AACSLVPGSFKCECIQGFRGAGTVN  232
             ++C   F      A C  +PG + CEC  G+   G  +
Sbjct  556  IDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFS  594


> Hs4503665
Length=1184

 Score = 94.4 bits (233),  Expect = 3e-19, Method: Compositional matrix adjust.
 Identities = 76/222 (34%), Positives = 99/222 (44%), Gaps = 20/222 (9%)

Query  25   CSRVEHAESCQSGDGFWCACQKGFT--PQGINLSSTCIDIDECAQGLDNCKQKGGDCVNI  82
            CSR EH   C +  G +  C K  T  P        C D+DECA G   C Q G  C N 
Sbjct  730  CSRGEH---CVNTLGSF-HCYKALTCEPGYALKDGECEDVDECAMGTHTC-QPGFLCQNT  784

Query  83   PGSFTCGCGP-----YRQEKDGVCIDINECSTNRGNCDENSDCINLDG----EEQLCKCH  133
             GSF C         + Q+ +G C+DINEC++    C     CIN  G    +     C 
Sbjct  785  KGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICA  844

Query  134  KGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTE  193
            +G+  ++D     C D+NEC      C    VC NL GSY+C+C AGF+ D+ G GC+  
Sbjct  845  RGYHASDD--GAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDV  902

Query  194  DFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCE  235
            + C             C    GS++C C  GF  A     CE
Sbjct  903  NECWASPG--RLCQHTCENTLGSYRCSCASGFLLAADGKRCE  942


 Score = 85.5 bits (210),  Expect = 2e-16, Method: Compositional matrix adjust.
 Identities = 72/219 (32%), Positives = 91/219 (41%), Gaps = 19/219 (8%)

Query  37   GDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTC----GCGP  92
            G    C+C  G+      +S  C DI+EC   L  C  +G  CVN  GSF C     C P
Sbjct  697  GGSAICSCFPGYAIMADGVS--CEDINECVTDLHTCS-RGEHCVNTLGSFHCYKALTCEP  753

Query  93   YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINE  152
                KDG C D++EC+     C     C N  G        +   G    P   C DINE
Sbjct  754  GYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINE  813

Query  153  CNENPSICPSNSVCTNLAGSYKCE-----CSAGFEPDSSGSGCVTEDFCGTGKNDCDTVF  207
            C      C     C N  GSY C+     C+ G+     G+ CV  + C TG + C    
Sbjct  814  CTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGE-G  872

Query  208  AACSLVPGSFKCECIQGF------RGAGTVNTCEPLPGN  240
              C  +PGS++C+C  GF      RG   VN C   PG 
Sbjct  873  QVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGR  911


 Score = 71.6 bits (174),  Expect = 2e-12, Method: Compositional matrix adjust.
 Identities = 61/195 (31%), Positives = 90/195 (46%), Gaps = 16/195 (8%)

Query  44    CQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEKDGVC  101
             C +G+     +  + C+D++EC  G+  C + G  C N+PGS+ C C  G  R      C
Sbjct  843   CARGY--HASDDGAKCVDVNECETGVHRCGE-GQVCHNLPGSYRCDCKAGFQRDAFGRGC  899

Query  102   IDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICP  161
             ID+NEC  + G   +++ C N  G  + C C  G+    D     C D+NEC        
Sbjct  900   IDVNECWASPGRLCQHT-CENTLGSYR-CSCASGFLLAADGKR--CEDVNECEAQRC---  952

Query  162   SNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCEC  221
              +  C N+ GSY+C C  G++    G  C   D C  G     T    C  VPGS++C C
Sbjct  953   -SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTF--RCLNVPGSYQCAC  1009

Query  222   I-QGFRGAGTVNTCE  235
               QG+       +C+
Sbjct  1010  PEQGYTMTANGRSCK  1024


 Score = 63.2 bits (152),  Expect = 7e-10, Method: Compositional matrix adjust.
 Identities = 58/183 (31%), Positives = 81/183 (44%), Gaps = 16/183 (8%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
             + C C+ GF  Q       CID++EC        Q    C N  GS+ C C   +    D
Sbjct  882   YRCDCKAGF--QRDAFGRGCIDVNECWASPGRLCQH--TCENTLGSYRCSCASGFLLAAD  937

Query  99    G-VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP  157
             G  C D+NEC   R +     +C N+ G  Q C C +G+    D     C DI+EC +  
Sbjct  938   GKRCEDVNECEAQRCS----QECANIYGSYQ-CYCRQGYQLAED--GHTCTDIDECAQGA  990

Query  158   SICPSNSVCTNLAGSYKCEC-SAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGS  216
              I      C N+ GSY+C C   G+   ++G  C   D C  G ++C      C  + GS
Sbjct  991   GIL-CTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEA-ETCHNIQGS  1048

Query  217   FKC  219
             F+C
Sbjct  1049  FRC  1051


 Score = 40.8 bits (94),  Expect = 0.004, Method: Compositional matrix adjust.
 Identities = 37/121 (30%), Positives = 49/121 (40%), Gaps = 12/121 (9%)

Query  114  CDENSDCINL---DGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLA  170
            C +N  C  +    G   +C C  G+    D   V+C DINEC  +   C     C N  
Sbjct  683  CKDNGPCKQVCSTVGGSAICSCFPGYAIMAD--GVSCEDINECVTDLHTCSRGEHCVNTL  740

Query  171  GSYKCECSAGFEPDSS--GSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCE----CIQG  224
            GS+ C  +   EP  +     C   D C  G + C   F  C    GSF C+    C+ G
Sbjct  741  GSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGF-LCQNTKGSFYCQARQRCMDG  799

Query  225  F  225
            F
Sbjct  800  F  800


> Hs18497288
Length=1256

 Score = 92.8 bits (229),  Expect = 1e-18, Method: Compositional matrix adjust.
 Identities = 70/203 (34%), Positives = 103/203 (50%), Gaps = 15/203 (7%)

Query  36   SGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YR  94
            +G  + C C +G+         +C+D++ECA+   +    GG C+N PG + C C P YR
Sbjct  635  TGGSYNCHCNRGYRLHVGAGGRSCVDLNECAK--PHLCGDGGFCINFPGHYKCNCYPGYR  692

Query  95   QE--KDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINE  152
             +  +  VC DI+EC  +  +C +   C N  G  +   C  G+         ACRD+NE
Sbjct  693  LKASRPPVCEDIDECR-DPSSCPDGK-CENKPGSFKCIACQPGYRSQGGG---ACRDVNE  747

Query  153  CNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSL  212
            C E  S C S   C NL GS++C C+ G+ P   G  C+  D C  G + CD     CS 
Sbjct  748  CAEG-SPC-SPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAG-DVCDN--GICSN  802

Query  213  VPGSFKCECIQGFRGAGTVNTCE  235
             PGSF+C+C+ G+  +   + CE
Sbjct  803  TPGSFQCQCLSGYHLSRDRSHCE  825


 Score = 79.0 bits (193),  Expect = 1e-14, Method: Compositional matrix adjust.
 Identities = 74/206 (35%), Positives = 94/206 (45%), Gaps = 20/206 (9%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEK  97
            F C C +G+ P     S  C+D+DEC  G D C    G C N PGSF C C  G +    
Sbjct  766  FRCTCAQGYAPAPDGRS--CLDVDECEAG-DVCDN--GICSNTPGSFQCQCLSGYHLSRD  820

Query  98   DGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP  157
               C DI+EC           DCIN +G  + C C +G      +    C+DI+EC+++P
Sbjct  821  RSHCEDIDECDFPAACI--GGDCINTNGSYR-CLCPQGHRLVGGR---KCQDIDECSQDP  874

Query  158  SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDC-----DTVFAACSL  212
            S+C  +  C NL GSY C C  GF P     GC  E      K +C     DTVF    L
Sbjct  875  SLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGC-EEVEQPHHKKECYLNFDDTVFCDSVL  933

Query  213  VPGSFKCECIQGFRGAGTVNTCEPLP  238
                 + EC     GAG  + CE  P
Sbjct  934  ATNVTQQECCCSL-GAGWGDHCEIYP  958


 Score = 62.0 bits (149),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 55/177 (31%), Positives = 76/177 (42%), Gaps = 20/177 (11%)

Query  61   DIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YR-QEKDGVCIDINECSTN-----RGN  113
            + DEC    + C    G+CV  P  ++C C P YR   +   C+D+NEC        RG 
Sbjct  574  ETDECRLNQNICGH--GECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGI  631

Query  114  CDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSY  173
            C       N       C C++G+  +      +C D+NEC + P +C     C N  G Y
Sbjct  632  CMNTGGSYN-------CHCNRGYRLHVGAGGRSCVDLNECAK-PHLCGDGGFCINFPGHY  683

Query  174  KCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKC-ECIQGFRGAG  229
            KC C  G+   +S    V ED     ++        C   PGSFKC  C  G+R  G
Sbjct  684  KCNCYPGYRLKASRPP-VCEDI-DECRDPSSCPDGKCENKPGSFKCIACQPGYRSQG  738


 Score = 35.4 bits (80),  Expect = 0.17, Method: Compositional matrix adjust.
 Identities = 57/214 (26%), Positives = 78/214 (36%), Gaps = 46/214 (21%)

Query  50    PQGINL--SSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKDGVCIDINE  106
             PQG  L     C DIDEC+Q    C   G  C N+ GS+ C C   +   +D    +  E
Sbjct  853   PQGHRLVGGRKCQDIDECSQDPSLCLPHGA-CKNLQGSYVCVCDEGFTPTQDQHGCEEVE  911

Query  107   CSTNRGNCDENSD---------CINLDGEE---------------------------QLC  130
                ++  C  N D           N+  +E                            LC
Sbjct  912   QPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLC  971

Query  131   KCHKGWTGNNDKPNV---ACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSG  187
                KG+T +N+  N    A RDI+EC    S       C N    Y+C C  GF  D + 
Sbjct  972   PDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNL  1031

Query  188   SGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCEC  221
               CV  D C   +++C      C    G ++C C
Sbjct  1032  LECVDVDEC-LDESNCRN--GVCENTRGGYRCAC  1062


 Score = 35.0 bits (79),  Expect = 0.22, Method: Compositional matrix adjust.
 Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 5/54 (9%)

Query  39    GFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP  92
             G+ C C++GF   G  L   C+D+DEC   LD    + G C N  G + C C P
Sbjct  1016  GYECYCKQGFYYDGNLLE--CVDVDEC---LDESNCRNGVCENTRGGYRCACTP  1064


 Score = 33.9 bits (76),  Expect = 0.55, Method: Compositional matrix adjust.
 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 6/68 (8%)

Query  129   LCKCHKGWTGNNDKPNVACRDINEC---NENPSICPSNSVCTNLAGSYKCECSAGFEPDS  185
             +C+C  G+    D     C DI+EC   N+   +C S   C N +GS++C C AGF    
Sbjct  1189  VCECPGGF--QLDASRARCVDIDECRELNQRGLLCKSER-CVNTSGSFRCVCKAGFARSR  1245

Query  186   SGSGCVTE  193
                 CV +
Sbjct  1246  PHGACVPQ  1253


 Score = 32.0 bits (71),  Expect = 2.0, Method: Compositional matrix adjust.
 Identities = 21/45 (46%), Positives = 26/45 (57%), Gaps = 5/45 (11%)

Query  50   PQGINL--SSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP  92
            PQG     S+ C DI+ECA     C+   GDC+N PGS+ C C P
Sbjct  342  PQGYKRLNSTHCQDINECAM-PGVCRH--GDCLNNPGSYRCVCPP  383


 Score = 31.6 bits (70),  Expect = 2.8, Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 29/72 (40%), Gaps = 1/72 (1%)

Query  166   CTNLAGSYKCECSAGFEPDSSGSGCVTEDFCG-TGKNDCDTVFAACSLVPGSFKCECIQG  224
             C    G   CEC  GF+ D+S + CV  D C    +         C    GSF+C C  G
Sbjct  1181  CVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAG  1240

Query  225   FRGAGTVNTCEP  236
             F  +     C P
Sbjct  1241  FARSRPHGACVP  1252


 Score = 31.2 bits (69),  Expect = 3.1, Method: Compositional matrix adjust.
 Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 5/62 (8%)

Query  132  CHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCV  191
            C +G+   N   +  C+DINEC   P +C  +  C N  GSY+C C  G     S + C+
Sbjct  341  CPQGYKRLN---STHCQDINEC-AMPGVC-RHGDCLNNPGSYRCVCPPGHSLGPSRTQCI  395

Query  192  TE  193
             +
Sbjct  396  AD  397


 Score = 30.0 bits (66),  Expect = 7.2, Method: Compositional matrix adjust.
 Identities = 26/69 (37%), Positives = 31/69 (44%), Gaps = 9/69 (13%)

Query  39    GFWCACQKGFTPQGINLSSTCIDIDECAQGLDN---CKQKGGDCVNIPGSFTCGC--GPY  93
             G  C C  GF  Q     + C+DIDEC +       CK +   CVN  GSF C C  G  
Sbjct  1187  GAVCECPGGF--QLDASRARCVDIDECRELNQRGLLCKSE--RCVNTSGSFRCVCKAGFA  1242

Query  94    RQEKDGVCI  102
             R    G C+
Sbjct  1243  RSRPHGACV  1251


 Score = 30.0 bits (66),  Expect = 7.5, Method: Compositional matrix adjust.
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 7/93 (7%)

Query  103   DINECSTNRGNCDENSDCINLD-GEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICP  161
             DI+EC        +   C+N   G E  CK    + GN     + C D++EC +  S C 
Sbjct  993   DIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNL----LECVDVDECLDE-SNC-  1046

Query  162   SNSVCTNLAGSYKCECSAGFEPDSSGSGCVTED  194
              N VC N  G Y+C C+   E   +   C++ +
Sbjct  1047  RNGVCENTRGGYRCACTPPAEYSPAQRQCLSPE  1079


> Hs17978491
Length=835

 Score = 92.4 bits (228),  Expect = 1e-18, Method: Compositional matrix adjust.
 Identities = 58/155 (37%), Positives = 81/155 (52%), Gaps = 15/155 (9%)

Query  42   CACQKGFTPQGINLS------STCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP---  92
            C C  G+ P     +      +TC D+DEC Q    CK  G  CVN  GS+TC C P   
Sbjct  91   CVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYG-TCVNTLGSYTCQCLPGFK  149

Query  93   YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWT---GNNDKPN-VACR  148
            +  E   VC D+NEC++ +  C  ++ C+N  G  Q C+C  GW    G+ + PN   C 
Sbjct  150  FIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQ-CRCRPGWQPIPGSPNGPNNTVCE  208

Query  149  DINECNENPSICPSNSVCTNLAGSYKCECSAGFEP  183
            D++EC+     C S++VC N  GSY C C  G++P
Sbjct  209  DVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKP  243


 Score = 84.7 bits (208),  Expect = 2e-16, Method: Compositional matrix adjust.
 Identities = 63/204 (30%), Positives = 94/204 (46%), Gaps = 22/204 (10%)

Query  42   CACQKGFTPQGINLSS---TCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP------  92
            C C  GF+     +++   TC DI+ECA        K  DC N  GS+ C C P      
Sbjct  42   CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS  101

Query  93   ----YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACR  148
                ++ E +  C D++EC  N   C     C+N  G    C+C  G+    + P V C 
Sbjct  102  GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT-CQCLPGFKFIPEDPKV-CT  159

Query  149  DINECNENPSICPSNSVCTNLAGSYKCECSAGFEP------DSSGSGCVTEDFCGTGKND  202
            D+NEC    + C S++ C N  GSY+C C  G++P        + + C   D C +G++ 
Sbjct  160  DVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQ  219

Query  203  CDTVFAACSLVPGSFKCECIQGFR  226
            CD+    C    GS+ C C  G++
Sbjct  220  CDSS-TVCFNTVGSYSCRCRPGWK  242


 Score = 67.4 bits (163),  Expect = 4e-11, Method: Compositional matrix adjust.
 Identities = 51/152 (33%), Positives = 78/152 (51%), Gaps = 23/152 (15%)

Query  101  CIDINECST-NRGNCDENSDCINLDGEEQLCKCHKGW-------TGNNDKPNVACRDINE  152
            C DINEC+T ++ +C + SDC N +G    C C  G+       T  N+  N  C+D++E
Sbjct  62   CDDINECATPSKVSCGKFSDCWNTEGSYD-CVCSPGYEPVSGAKTFKNESEN-TCQDVDE  119

Query  153  CNENPSICPSNSVCTNLAGSYKCECSAGFE--PDSSGSGCVTEDFCGTGKNDCDTVFAAC  210
            C +NP +C S   C N  GSY C+C  GF+  P+     C   + C +G+N C +    C
Sbjct  120  CQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKV-CTDVNECTSGQNPCHSS-THC  177

Query  211  SLVPGSFKCECIQGFRGAGTVNTCEPLPGNED  242
                GS++C C  G+         +P+PG+ +
Sbjct  178  LNNVGSYQCRCRPGW---------QPIPGSPN  200


 Score = 54.3 bits (129),  Expect = 4e-07, Method: Compositional matrix adjust.
 Identities = 43/148 (29%), Positives = 60/148 (40%), Gaps = 23/148 (15%)

Query  22   YDHCSRVEHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVN  81
            Y  C     + +CQ   GF       F P+       C D++EC  G + C      C+N
Sbjct  130  YGTCVNTLGSYTCQCLPGF------KFIPED---PKVCTDVNECTSGQNPC-HSSTHCLN  179

Query  82   IPGSFTCGCGPYRQEKDG--------VCIDINECSTNRGNCDENSDCINLDGEEQLCKCH  133
              GS+ C C P  Q   G        VC D++ECS+ +  CD ++ C N  G    C+C 
Sbjct  180  NVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYS-CRCR  238

Query  134  KGWTGNNDKPN----VACRDINECNENP  157
             GW   +  PN      C D+      P
Sbjct  239  PGWKPRHGIPNNQKDTVCEDMTFSTWTP  266


> Hs4503565
Length=886

 Score = 92.0 bits (227),  Expect = 2e-18, Method: Compositional matrix adjust.
 Identities = 68/179 (37%), Positives = 92/179 (51%), Gaps = 26/179 (14%)

Query  26   SRV--EHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIP  83
            SRV  EH++   S   + C+CQ GF    I+ +STC D++ECA     C +    C N  
Sbjct  139  SRVCPEHSDCVNSMGSYSCSCQVGF----ISRNSTCEDVNECADP-RACPEHA-TCNNTV  192

Query  84   GSFTCGCGPYRQEKDG---------VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHK  134
            G+++C C P  +   G          C DI+EC+     C  NS C N  G    C CH 
Sbjct  193  GNYSCFCNPGFESSSGHLSCQGLKASCEDIDECTEM---CPINSTCTNTPGS-YFCTCHP  248

Query  135  GWTGNNDKPN-----VACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGS  188
            G+  ++ + N     V CRDI+EC ++PS C  NS+CTN  GSY C C  GF P+  GS
Sbjct  249  GFAPSSGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIVGFHPNPEGS  307


 Score = 85.1 bits (209),  Expect = 2e-16, Method: Compositional matrix adjust.
 Identities = 76/248 (30%), Positives = 104/248 (41%), Gaps = 38/248 (15%)

Query  38   DGFWCACQKGF-TPQGINLSS----TCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP  92
            D ++C C++GF +  G N        C DIDEC+Q    C      C N+ G + C C  
Sbjct  52   DSYYCTCKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG-PNSSCKNLSGRYKCSCLD  110

Query  93   YRQEKDG-----------VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNND  141
                  G            C DINEC T+R  C E+SDC+N  G    C C  G+   N 
Sbjct  111  GFSSPTGNDWVPGKPGNFSCTDINECLTSRV-CPEHSDCVNSMGSYS-CSCQVGFISRNS  168

Query  142  KPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKN  201
                 C D+NEC  +P  CP ++ C N  G+Y C C+ GFE  S    C          +
Sbjct  169  ----TCEDVNEC-ADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSCQGLKASCEDID  223

Query  202  DCDT---VFAACSLVPGSFKCECIQGFRGAGTVNTCEPLPGNEDLACTTLGLTCGDYKYC  258
            +C     + + C+  PGS+ C C  GF            P +  L  T  G+ C D   C
Sbjct  224  ECTEMCPINSTCTNTPGSYFCTCHPGFA-----------PSSGQLNFTDQGVECRDIDEC  272

Query  259  TKSTTQAG  266
             +  +  G
Sbjct  273  RQDPSTCG  280


 Score = 78.6 bits (192),  Expect = 2e-14, Method: Compositional matrix adjust.
 Identities = 73/226 (32%), Positives = 100/226 (44%), Gaps = 21/226 (9%)

Query  13   SSTPCDAGGYDHCSRVEHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNC  72
            S +P   G    C  +     C   DGF       + P G   + +C DI+EC      C
Sbjct  85   SQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVP-GKPGNFSCTDINECLTS-RVC  142

Query  73   KQKGGDCVNIPGSFTCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKC  132
             +   DCVN  GS++C C      ++  C D+NEC+  R  C E++ C N  G    C C
Sbjct  143  PEHS-DCVNSMGSYSCSCQVGFISRNSTCEDVNECADPRA-CPEHATCNNTVGNYS-CFC  199

Query  133  HKGWTGNNDKPN-----VACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDS--  185
            + G+  ++   +      +C DI+EC E   +CP NS CTN  GSY C C  GF P S  
Sbjct  200  NPGFESSSGHLSCQGLKASCEDIDECTE---MCPINSTCTNTPGSYFCTCHPGFAPSSGQ  256

Query  186  -----SGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFR  226
                  G  C   D C    + C    + C+   GS+ C CI GF 
Sbjct  257  LNFTDQGVECRDIDECRQDPSTCGPN-SICTNALGSYSCGCIVGFH  301


 Score = 62.0 bits (149),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 65/198 (32%), Positives = 86/198 (43%), Gaps = 33/198 (16%)

Query  79   CVNIPGSFTCGC--------GPYRQEKDGV-CIDINECSTNRGNCDENSDCINLDGEEQL  129
            C N   S+ C C        G    +  GV C DI+ECS +   C  NS C NL G  + 
Sbjct  47   CTNTVDSYYCTCKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYK-  105

Query  130  CKCHKGW---TGNNDKP----NVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFE  182
            C C  G+   TGN+  P    N +C DINEC     +CP +S C N  GSY C C  GF 
Sbjct  106  CSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-LTSRVCPEHSDCVNSMGSYSCSCQVGF-  163

Query  183  PDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCEPLPGNED  242
              S  S C   + C   +   +   A C+   G++ C C  GF  +           +  
Sbjct  164  -ISRNSTCEDVNECADPRACPE--HATCNNTVGNYSCFCNPGFESS-----------SGH  209

Query  243  LACTTLGLTCGDYKYCTK  260
            L+C  L  +C D   CT+
Sbjct  210  LSCQGLKASCEDIDECTE  227


 Score = 37.4 bits (85),  Expect = 0.040, Method: Compositional matrix adjust.
 Identities = 38/132 (28%), Positives = 51/132 (38%), Gaps = 24/132 (18%)

Query  130  CKCHKGWTGN---NDKPNVA---CRDINECNENPSICPSNSVCTNLAGSYKCECSAGF--  181
            C  H  W G+     KPN     CRD        ++CP+ + CTN   SY C C  GF  
Sbjct  13   CVMH-SWEGHIRPTRKPNTKGNNCRD-------STLCPAYATCTNTVDSYYCTCKQGFLS  64

Query  182  -----EPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCEP  236
                      G  C   D C      C    ++C  + G +KC C+ GF      +    
Sbjct  65   SNGQNHFKDPGVRCKDIDECSQSPQPCGPN-SSCKNLSGRYKCSCLDGFSSPTGNDWVPG  123

Query  237  LPGNEDLACTTL  248
             PGN   +CT +
Sbjct  124  KPGN--FSCTDI  133


> Hs4505037
Length=1587

 Score = 91.7 bits (226),  Expect = 2e-18, Method: Compositional matrix adjust.
 Identities = 74/202 (36%), Positives = 96/202 (47%), Gaps = 22/202 (10%)

Query  39   GFWCACQKGF--TPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQ  95
            G+ CAC  GF  +PQG    + CID+DEC +    C    G C N PGSF C CGP +R 
Sbjct  530  GYTCACDSGFRLSPQG----TRCIDVDECRRVPPPCAP--GRCENSPGSFRCVCGPGFRA  583

Query  96   -EKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECN  154
              +   C+D++EC      CD    C N  G   LC C  G+         +C+D++EC 
Sbjct  584  GPRAAECLDVDECHRVPPPCDLGR-CENTPG-SFLCVCPAGYQAAPH--GASCQDVDECT  639

Query  155  ENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTE-DFCGTGKNDCDTVFAACSLV  213
            ++P +C     C NL GS++C C AGF     GS C  + D C      C      C   
Sbjct  640  QSPGLC-GRGGCKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGP--GRCDNT  692

Query  214  PGSFKCECIQGFRGAGTVNTCE  235
             GSF C C  GFR  G    C+
Sbjct  693  AGSFHCACPAGFRSRGPGAPCQ  714


 Score = 80.5 bits (197),  Expect = 5e-15, Method: Compositional matrix adjust.
 Identities = 76/222 (34%), Positives = 105/222 (47%), Gaps = 24/222 (10%)

Query  30    HAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCG  89
             H E   +   F C C  G+ P      ++C+D+DEC++  D C+   G C N  GSF C 
Sbjct  854   HGECLNTDGSFACTCAPGYRPG--PRGASCLDVDECSE-EDLCQS--GICTNTDGSFECI  908

Query  90    CGP-YRQEKD-GVCIDINECSTNRGNCDENSDCINLDGEEQLCK-CHKGWTGNNDKPNVA  146
             C P +R   D   C+D++EC         +  C N  G  +  + C  G+      P   
Sbjct  909   CPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAG---PEGT  965

Query  147   CRDINECNE-NPSICPSNSVCTNLAGSYKC--ECSAGFEPDSSGSGCVTEDFCGTGKNDC  203
             C D++EC E  P IC +   C N  GSY+C   C  G++P + G GC   D C   ++ C
Sbjct  966   CDDVDECQEYGPEICGAQR-CENTPGSYRCTPACDPGYQP-TPGGGCQDVDEC-RNRSFC  1022

Query  204   DTVFAACSLVPGSFKCECIQGFRGAG------TVNTCEPLPG  239
                 A C  +PGSF+C C QG+ GA        VN CE L G
Sbjct  1023  G-AHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG  1063


 Score = 76.6 bits (187),  Expect = 6e-14, Method: Compositional matrix adjust.
 Identities = 66/202 (32%), Positives = 91/202 (45%), Gaps = 17/202 (8%)

Query  23   DHCSRVEHA---ESCQSGDG-FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGD  78
            D C RV        C++  G F C C  G+  Q     ++C D+DEC Q    C + G  
Sbjct  594  DECHRVPPPCDLGRCENTPGSFLCVCPAGY--QAAPHGASCQDVDECTQSPGLCGRGG--  649

Query  79   CVNIPGSFTCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTG  138
            C N+PGSF C C P          D++EC+     C     C N  G    C C  G+  
Sbjct  650  CKNLPGSFRCVC-PAGFRGSACEEDVDECAQEPPPCGPGR-CDNTAGSFH-CACPAGFRS  706

Query  139  NNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGT  198
                P   C+D++EC  +P  C +   C N  GS++C C  GF+P+++GS C   D C  
Sbjct  707  RG--PGAPCQDVDECARSPPPC-TYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC--  761

Query  199  GKNDCDTVFAACSLVPGSFKCE  220
             +N        C   PGSF+C 
Sbjct  762  -ENHLACPGQECVNSPGSFQCR  782


 Score = 71.2 bits (173),  Expect = 3e-12, Method: Compositional matrix adjust.
 Identities = 72/207 (34%), Positives = 98/207 (47%), Gaps = 18/207 (8%)

Query  23    DHCSRVEHAES--CQSGDG-FWCACQKGFTPQGINLSSTCIDIDECAQ-GLDNCKQKGGD  78
             D CS  +  +S  C + DG F C C  G    G +L+S C+D+DEC + G   C  +   
Sbjct  885   DECSEEDLCQSGICTNTDGSFECICPPGHR-AGPDLAS-CLDVDECRERGPALCGSQ--R  940

Query  79    CVNIPGSFTC--GCGP-YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCK-CHK  134
             C N PGS+ C   C P Y    +G C D++EC            C N  G  +    C  
Sbjct  941   CENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDP  1000

Query  135   GWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTED  194
             G+      P   C+D++EC  N S C +++VC NL GS++C C  G+E    G  CV  +
Sbjct  1001  GY---QPTPGGGCQDVDECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVN  1056

Query  195   FCGTGKNDCDTVFAACSLVPGSFKCEC  221
              C T +  C    A C  V GSF C C
Sbjct  1057  ECETLQGVCGA--ALCENVEGSFLCVC  1081


 Score = 70.5 bits (171),  Expect = 5e-12, Method: Compositional matrix adjust.
 Identities = 62/196 (31%), Positives = 82/196 (41%), Gaps = 27/196 (13%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEK  97
            F CAC  GF  +G    + C D+DECA+    C    G C N  GSF C C  G      
Sbjct  696  FHCACPAGFRSRGPG--APCQDVDECARSPPPCTY--GRCENTEGSFQCVCPMGFQPNTA  751

Query  98   DGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP  157
               C D++EC  N   C    +C+N  G  Q   C  G   +  +    C D++EC+   
Sbjct  752  GSECEDVDECE-NHLAC-PGQECVNSPGSFQCRTCPSGHHLHRGR----CTDVDECSSGA  805

Query  158  SICPSNSVCTNLAGSYKCECSAGFEPDSSGSG-------CVTEDFCGTGKNDCDTVFAAC  210
              C  +  CTN  GS++C C+ G+   S   G       C+  DFC             C
Sbjct  806  PPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFC--------FPHGEC  857

Query  211  SLVPGSFKCECIQGFR  226
                GSF C C  G+R
Sbjct  858  LNTDGSFACTCAPGYR  873


 Score = 64.3 bits (155),  Expect = 4e-10, Method: Compositional matrix adjust.
 Identities = 52/155 (33%), Positives = 70/155 (45%), Gaps = 11/155 (7%)

Query  77   GDCVNIPGSFTCGCGP-YRQEKDGV-CIDINECSTNRGNCDENSDCINLDGEEQLCKCHK  134
            G C++ P  +TC C   +R    G  CID++EC      C     C N  G  + C C  
Sbjct  522  GRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR-CENSPGSFR-CVCGP  579

Query  135  GWTGNNDKPNVA-CRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTE  193
            G+      P  A C D++EC+  P  C     C N  GS+ C C AG++    G+ C   
Sbjct  580  GFRAG---PRAAECLDVDECHRVPPPC-DLGRCENTPGSFLCVCPAGYQAAPHGASCQDV  635

Query  194  DFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGA  228
            D C      C      C  +PGSF+C C  GFRG+
Sbjct  636  DECTQSPGLCGR--GGCKNLPGSFRCVCPAGFRGS  668


 Score = 42.0 bits (97),  Expect = 0.002, Method: Compositional matrix adjust.
 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query  117   NSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICP--SNSVCTNLAGSYK  174
             N  C+ +  E   C+C  G+    D   +AC DINEC+E  +  P   N+ C N  GS++
Sbjct  1508  NDRCVRVP-EGFTCRCFDGY--RLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFR  1564

Query  175   CECSAGFEPDSSGSGCV  191
             C C  GF P      C 
Sbjct  1565  CICRPGFAPTHQPHHCA  1581


 Score = 35.0 bits (79),  Expect = 0.23, Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 28/57 (49%), Gaps = 4/57 (7%)

Query  36    SGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP  92
             +  G+ C C  G+      L   CID DECA     C+  GG CVN  GS+ C C P
Sbjct  1236  TAPGYSCYCSNGYYYHTQRLE--CIDNDECADEEPACE--GGRCVNTVGSYHCTCEP  1288


 Score = 35.0 bits (79),  Expect = 0.23, Method: Compositional matrix adjust.
 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 4/74 (5%)

Query  141  DKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGK  200
            ++ N +C D++EC         +  C N  G Y C C  GF  DSS S C+++      K
Sbjct  312  ERVNGSCEDVDECATGGRC--QHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAK  369

Query  201  NDCDTVF--AACSL  212
              C  V     CSL
Sbjct  370  GPCFRVLRDGGCSL  383


 Score = 32.7 bits (73),  Expect = 1.1, Method: Compositional matrix adjust.
 Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 4/92 (4%)

Query  103   DINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPS  162
             D++EC   R    ++  C+N       C C  G+  +  +  + C D +EC +    C  
Sbjct  1216  DVDECQLFRDQVCKSGVCVNT-APGYSCYCSNGYYYHTQR--LECIDNDECADEEPAC-E  1271

Query  163   NSVCTNLAGSYKCECSAGFEPDSSGSGCVTED  194
                C N  GSY C C      D S   CV+ +
Sbjct  1272  GGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNE  1303


 Score = 31.6 bits (70),  Expect = 2.3, Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 7/82 (8%)

Query  69    LDNCKQKGGDCVNIPGSFTCGC-GPYRQEKDGV-CIDINECSTNRGNCD--ENSDCINLD  124
             LD C      CV +P  FTC C   YR +   + C+DINEC           N+ C+N D
Sbjct  1503  LDGCTND--RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTD  1560

Query  125   GEEQLCKCHKGWTGNNDKPNVA  146
             G  + C C  G+   +   + A
Sbjct  1561  GSFR-CICRPGFAPTHQPHHCA  1581


 Score = 31.6 bits (70),  Expect = 2.5, Method: Compositional matrix adjust.
 Identities = 25/95 (26%), Positives = 40/95 (42%), Gaps = 3/95 (3%)

Query  127   EQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSS  186
             + LC   +G+   +   ++  RD++EC         + VC N A  Y C CS G+   + 
Sbjct  1195  QSLCPHGRGYLAPSGDLSLR-RDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQ  1253

Query  187   GSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCEC  221
                C+  D C   +  C+     C    GS+ C C
Sbjct  1254  RLECIDNDECADEEPACEG--GRCVNTVGSYHCTC  1286


 Score = 30.0 bits (66),  Expect = 7.0, Method: Compositional matrix adjust.
 Identities = 21/76 (27%), Positives = 30/76 (39%), Gaps = 1/76 (1%)

Query  162   SNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDT-VFAACSLVPGSFKCE  220
             +N  C  +   + C C  G+  D +   CV  + C   +      V A C    GSF+C 
Sbjct  1507  TNDRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCI  1566

Query  221   CIQGFRGAGTVNTCEP  236
             C  GF      + C P
Sbjct  1567  CRPGFAPTHQPHHCAP  1582


 Score = 29.6 bits (65),  Expect = 8.4, Method: Compositional matrix adjust.
 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 12/90 (13%)

Query  27   RVEHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSF  86
            R+ ++E   + DG    C  GF      ++ +C D+DECA G   C+   G+C N  G +
Sbjct  293  RLGNSERVSAPDG---PCPTGFE----RVNGSCEDVDECATG-GRCQH--GECANTRGGY  342

Query  87   TCGC--GPYRQEKDGVCIDINECSTNRGNC  114
            TC C  G         CI  +  S  +G C
Sbjct  343  TCVCPDGFLLDSSRSSCISQHVISEAKGPC  372


 Score = 29.6 bits (65),  Expect = 8.5, Method: Compositional matrix adjust.
 Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 4/67 (5%)

Query  61    DIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEKDGVCIDINECSTNRGNCDENS  118
             D+DEC    D    K G CVN    ++C C  G Y   +   CID +EC+     C E  
Sbjct  1216  DVDECQLFRDQ-VCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPAC-EGG  1273

Query  119   DCINLDG  125
              C+N  G
Sbjct  1274  RCVNTVG  1280


> Hs4557731
Length=1394

 Score = 91.7 bits (226),  Expect = 2e-18, Method: Compositional matrix adjust.
 Identities = 68/191 (35%), Positives = 99/191 (51%), Gaps = 13/191 (6%)

Query  33   SCQSGDG-FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCG  91
             C++ +G F C C +G+   G  L   C DI+EC +    C++  GDC+N  GS+ C C 
Sbjct  807  QCRNTEGSFQCVCDQGYRASG--LGDHCEDINECLEDKSVCQR--GDCINTAGSYDCTCP  862

Query  92   P-YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDI  150
              ++ + +  C DINEC  + G C    +C+N +G    C C +G++ + D     C DI
Sbjct  863  DGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEGSFH-CVCQQGFSISAD--GRTCEDI  918

Query  151  NECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAAC  210
            +EC  N ++C S+  C N AGS++C C  GF+    G GCV  + C      C   F  C
Sbjct  919  DECVNN-TVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAF--C  975

Query  211  SLVPGSFKCEC  221
              V GSF C C
Sbjct  976  ENVEGSFLCVC  986


 Score = 89.0 bits (219),  Expect = 1e-17, Method: Compositional matrix adjust.
 Identities = 81/223 (36%), Positives = 113/223 (50%), Gaps = 26/223 (11%)

Query  23   DHCSRVEHAES---CQSGDG-FWCACQKGF--TPQGINLSSTCIDIDECAQGLDNCKQKG  76
            D C++V+H  S   C++ +G F C C  GF  + +G N    CID+DEC +  D C +  
Sbjct  590  DECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTN----CIDVDECLRP-DVCGE--  642

Query  77   GDCVNIPGSFTCGC--GPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHK  134
            G CVN  G+F C      YR  + G C DI+EC  N   C  +  C+N  G  Q   C +
Sbjct  643  GHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDEC-LNPSTC-PDEQCVNSPGSYQCVPCTE  700

Query  135  GWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTED  194
            G+ G N +    C D++EC E P++C +N  C+NL GSY C C  G+        C   D
Sbjct  701  GFRGWNGQ----CLDVDECLE-PNVC-ANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDID  754

Query  195  FCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCEPL  237
             C  G N C  V   C    GSF+C C QG++ +   + CE +
Sbjct  755  ECQQG-NLC--VNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDI  794


 Score = 85.5 bits (210),  Expect = 2e-16, Method: Compositional matrix adjust.
 Identities = 81/216 (37%), Positives = 101/216 (46%), Gaps = 22/216 (10%)

Query  33   SCQSGDG-FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCG  91
             C++ +G F C C +G+  Q       C DIDEC Q    C    G C N  GSF C C 
Sbjct  766  QCKNTEGSFRCTCGQGY--QLSAAKDQCEDIDEC-QHRHLCAH--GQCRNTEGSFQCVCD  820

Query  92   P-YRQEKDG-VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRD  149
              YR    G  C DINEC  ++  C +  DCIN  G    C C  G+  +++K    C+D
Sbjct  821  QGYRASGLGDHCEDINECLEDKSVC-QRGDCINTAGSYD-CTCPDGFQLDDNK---TCQD  875

Query  150  INECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAA  209
            INEC E+P +C     C N  GS+ C C  GF   + G  C   D C      CD+    
Sbjct  876  INEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDS-HGF  932

Query  210  CSLVPGSFKCECIQGF------RGAGTVNTCEPLPG  239
            C    GSF+C C QGF      +G   VN CE L G
Sbjct  933  CDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSG  968


 Score = 84.3 bits (207),  Expect = 3e-16, Method: Compositional matrix adjust.
 Identities = 74/221 (33%), Positives = 105/221 (47%), Gaps = 24/221 (10%)

Query  18   DAGGYDHCSRVEHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGG  77
            D  G  HC     A  C+  D  +   Q+G           C DIDEC   L+       
Sbjct  638  DVCGEGHCVNTVGAFRCEYCDSGYRMTQRG----------RCEDIDEC---LNPSTCPDE  684

Query  78   DCVNIPGSFTC-GCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGW  136
             CVN PGS+ C  C    +  +G C+D++EC     N   N DC NL+G   +C CHKG+
Sbjct  685  QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECL--EPNVCANGDCSNLEGS-YMCSCHKGY  741

Query  137  TGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFC  196
            T   D  +  CRDI+EC +  ++C  N  C N  GS++C C  G++  ++   C   D C
Sbjct  742  TRTPDHKH--CRDIDECQQG-NLC-VNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDEC  797

Query  197  GTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCEPL  237
               ++ C      C    GSF+C C QG+R +G  + CE +
Sbjct  798  -QHRHLC--AHGQCRNTEGSFQCVCDQGYRASGLGDHCEDI  835


 Score = 75.1 bits (183),  Expect = 2e-13, Method: Compositional matrix adjust.
 Identities = 77/208 (37%), Positives = 96/208 (46%), Gaps = 32/208 (15%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQ---E  96
            + C+C KG+T    +    C DIDEC QG + C    G C N  GSF C CG   Q    
Sbjct  733  YMCSCHKGYTRTPDH--KHCRDIDECQQG-NLCV--NGQCKNTEGSFRCTCGQGYQLSAA  787

Query  97   KDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGW--TGNNDKPNVACRDINECN  154
            KD  C DI+EC  +R  C  +  C N +G  Q C C +G+  +G  D     C DINEC 
Sbjct  788  KDQ-CEDIDECQ-HRHLC-AHGQCRNTEGSFQ-CVCDQGYRASGLGDH----CEDINECL  839

Query  155  ENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGS-----GCVTEDFCGTGKNDCDTVFAA  209
            E+ S+C     C N AGSY C C  GF+ D + +      C     CG            
Sbjct  840  EDKSVCQRGD-CINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQ--------GE  890

Query  210  CSLVPGSFKCECIQGFRGAGTVNTCEPL  237
            C    GSF C C QGF  +    TCE +
Sbjct  891  CLNTEGSFHCVCQQGFSISADGRTCEDI  918


 Score = 58.5 bits (140),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 56/171 (32%), Positives = 82/171 (47%), Gaps = 16/171 (9%)

Query  61   DIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEKDGVCIDINECSTNRGNCDENS  118
            +I+EC    D C    G C+N+P  +TC C  G    E+   C+DI+EC+  +  C +  
Sbjct  546  EINECTVNPDICG--AGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGR  603

Query  119  DCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCE-C  177
             C N +G   LC C  G+  + +  N  C D++EC   P +C     C N  G+++CE C
Sbjct  604  -CENTEGSF-LCICPAGFMASEEGTN--CIDVDEC-LRPDVC-GEGHCVNTVGAFRCEYC  657

Query  178  SAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKC-ECIQGFRG  227
             +G+     G  C   D C    N        C   PGS++C  C +GFRG
Sbjct  658  DSGYRMTQRGR-CEDIDEC---LNPSTCPDEQCVNSPGSYQCVPCTEGFRG  704


 Score = 48.1 bits (113),  Expect = 3e-05, Method: Compositional matrix adjust.
 Identities = 29/72 (40%), Positives = 38/72 (52%), Gaps = 5/72 (6%)

Query  122  NLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGF  181
            +  G  Q+ +C  G+   N   N  C+DINEC     +CP N  C N  GSY+C C  GF
Sbjct  276  SYHGYNQMMECLPGYKRVN---NTFCQDINECQLQ-GVCP-NGECLNTMGSYRCTCKIGF  330

Query  182  EPDSSGSGCVTE  193
             PD + S CV +
Sbjct  331  GPDPTFSSCVPD  342


 Score = 39.7 bits (91),  Expect = 0.010, Method: Compositional matrix adjust.
 Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 7/79 (8%)

Query  116   ENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNE---NPSICPSNSVCTNLAGS  172
             EN  C+ +  E   C C  G+  + D   + C D+NEC+E     S+C  N+ C N  GS
Sbjct  1305  ENGRCVRVQ-EGYTCDCLDGY--HLDTAKMTCFDVNECDELNNRMSLC-KNAKCINTDGS  1360

Query  173   YKCECSAGFEPDSSGSGCV  191
             YKC C  G+ P    + C 
Sbjct  1361  YKCLCLPGYVPSDKPNYCT  1379


 Score = 34.3 bits (77),  Expect = 0.37, Method: Compositional matrix adjust.
 Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 1/76 (1%)

Query  163   NSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVF-AACSLVPGSFKCEC  221
             N  C  +   Y C+C  G+  D++   C   + C    N       A C    GS+KC C
Sbjct  1306  NGRCVRVQEGYTCDCLDGYHLDTAKMTCFDVNECDELNNRMSLCKNAKCINTDGSYKCLC  1365

Query  222   IQGFRGAGTVNTCEPL  237
             + G+  +   N C PL
Sbjct  1366  LPGYVPSDKPNYCTPL  1381


> Hs7305025
Length=823

 Score = 91.7 bits (226),  Expect = 2e-18, Method: Compositional matrix adjust.
 Identities = 53/134 (39%), Positives = 75/134 (55%), Gaps = 9/134 (6%)

Query  57   STCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP---YRQEKDGVCIDINECSTNRGN  113
            +TC D+DEC Q    CK  G  CVN  GS+TC C P    + E   +C D+NEC++ +  
Sbjct  115  NTCQDVDECQQNPRLCKSYG-TCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNP  173

Query  114  CDENSDCINLDGEEQLCKCHKGWT---GNNDKPN-VACRDINECNENPSICPSNSVCTNL  169
            C  ++ C+N  G  Q C+C  GW    G+ + PN   C D++EC+     C S++VC N 
Sbjct  174  CHSSTHCLNNVGSYQ-CRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNT  232

Query  170  AGSYKCECSAGFEP  183
             GSY C C  G++P
Sbjct  233  VGSYSCRCRPGWKP  246


 Score = 84.3 bits (207),  Expect = 4e-16, Method: Compositional matrix adjust.
 Identities = 62/204 (30%), Positives = 94/204 (46%), Gaps = 22/204 (10%)

Query  42   CACQKGFTPQGINLSS---TCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP------  92
            C C  GF+     +++   TC DI+ECA        K  DC N  GS+ C C P      
Sbjct  45   CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS  104

Query  93   ----YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACR  148
                ++ E +  C D++EC  N   C     C+N  G    C+C  G+    + P + C 
Sbjct  105  GAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYT-CQCLPGFKLKPEDPKL-CT  162

Query  149  DINECNENPSICPSNSVCTNLAGSYKCECSAGFEP------DSSGSGCVTEDFCGTGKND  202
            D+NEC    + C S++ C N  GSY+C C  G++P        + + C   D C +G++ 
Sbjct  163  DVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQ  222

Query  203  CDTVFAACSLVPGSFKCECIQGFR  226
            CD+    C    GS+ C C  G++
Sbjct  223  CDSS-TVCFNTVGSYSCRCRPGWK  245


 Score = 67.8 bits (164),  Expect = 3e-11, Method: Compositional matrix adjust.
 Identities = 50/151 (33%), Positives = 76/151 (50%), Gaps = 21/151 (13%)

Query  101  CIDINECST-NRGNCDENSDCINLDGEEQLCKCHKGW-------TGNNDKPNVACRDINE  152
            C DINEC+T ++ +C + SDC N +G    C C  G+       T  N+  N  C+D++E
Sbjct  65   CDDINECATLSKVSCGKFSDCWNTEGSYD-CVCSPGYEPVSGAKTFKNESEN-TCQDVDE  122

Query  153  CNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSG-CVTEDFCGTGKNDCDTVFAACS  211
            C +NP +C S   C N  GSY C+C  GF+        C   + C +G+N C +    C 
Sbjct  123  CQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSS-THCL  181

Query  212  LVPGSFKCECIQGFRGAGTVNTCEPLPGNED  242
               GS++C C  G+         +P+PG+ +
Sbjct  182  NNVGSYQCRCRPGW---------QPIPGSPN  203


 Score = 55.1 bits (131),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 19/132 (14%)

Query  40   FWCACQKGFT--PQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEK  97
            + C C  GF   P+   L   C D++EC  G + C      C+N  GS+ C C P  Q  
Sbjct  143  YTCQCLPGFKLKPEDPKL---CTDVNECTSGQNPC-HSSTHCLNNVGSYQCRCRPGWQPI  198

Query  98   DG--------VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPN----V  145
             G        VC D++ECS+ +  CD ++ C N  G    C+C  GW   +  PN     
Sbjct  199  PGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYS-CRCRPGWKPRHGIPNNQKDT  257

Query  146  ACRDINECNENP  157
             C D+      P
Sbjct  258  VCEDMTFSTWTP  269


> Hs4503663
Length=683

 Score = 85.9 bits (211),  Expect = 1e-16, Method: Compositional matrix adjust.
 Identities = 75/232 (32%), Positives = 114/232 (49%), Gaps = 18/232 (7%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
            F C C+ G+   GI  S  C+D++EC +     +  G  C N  GS+ C C   +R   D
Sbjct  380  FRCECKTGYYFDGI--SRMCVDVNECQRYPG--RLCGHKCENTLGSYLCSCSVGFRLSVD  435

Query  99   GV-CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP  157
            G  C DINECS++  +     +C N+ G  Q C C +G+   +D   V C DI+EC    
Sbjct  436  GRSCEDINECSSSPCS----QECANVYGSYQ-CYCRRGYQ-LSDVDGVTCEDIDECALPT  489

Query  158  SICPSNSVCTNLAGSYKCEC-SAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGS  216
                 +  C N+ GS++C C S+G+    +G  C   D C TG ++C ++   C  + G+
Sbjct  490  GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNC-SINETCFNIQGA  548

Query  217  FKC---ECIQGFRGAGTVNTCEPLPGNEDLACTTLGLTCGDYKYCTKSTTQA  265
            F+C   EC + +R +     CE LP +E+  C+ L L    Y     +  QA
Sbjct  549  FRCLAFECPENYRRSAATR-CERLPCHENRECSKLPLRITYYHLSFPTNIQA  599


 Score = 80.5 bits (197),  Expect = 5e-15, Method: Compositional matrix adjust.
 Identities = 71/221 (32%), Positives = 97/221 (43%), Gaps = 20/221 (9%)

Query  36   SGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTC----GCG  91
            +GD   C+C  G+  Q ++   +C D++EC  G  +C+  G  C+N  GSF C     CG
Sbjct  193  TGDEVVCSCFVGY--QLLSDGVSCEDVNECITGSHSCR-LGESCINTVGSFRCQRDSSCG  249

Query  92   P-YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDI  150
              Y   +D  C DI+EC +   NC  +  C N  G  +     +  +G        C DI
Sbjct  250  TGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDI  309

Query  151  NECNENPSICPSNSVCTNLAGSYKCE-----CSAGFEPDSSGSGCVTEDFCGTGKNDCDT  205
            NEC    + CP    C N  GSY C+     C  G+  +  G+ CV  D C      C  
Sbjct  310  NECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGK  369

Query  206  VFAACSLVPGSFKCECIQGFRGAGT------VNTCEPLPGN  240
                C   PGSF+CEC  G+   G       VN C+  PG 
Sbjct  370  GH-RCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR  409


 Score = 78.2 bits (191),  Expect = 3e-14, Method: Compositional matrix adjust.
 Identities = 68/187 (36%), Positives = 91/187 (48%), Gaps = 18/187 (9%)

Query  57   STCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEKDGVCIDINECSTNRGNC  114
            + C+D+DECA   + C  KG  CVN PGSF C C  G Y      +C+D+NEC    G  
Sbjct  352  TRCVDVDECAPPAEPCG-KGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL  410

Query  115  DENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYK  174
                 C N  G   LC C  G+  + D    +C DINEC+ +P     +  C N+ GSY+
Sbjct  411  C-GHKCENTLGS-YLCSCSVGFRLSVD--GRSCEDINECSSSPC----SQECANVYGSYQ  462

Query  175  CECSAGFE-PDSSGSGCVTEDFCG--TGKNDCDTVFAACSLVPGSFKCEC-IQGFRGAGT  230
            C C  G++  D  G  C   D C   TG + C      C  +PGSF+C C   G+R A  
Sbjct  463  CYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY---RCINIPGSFQCSCPSSGYRLAPN  519

Query  231  VNTCEPL  237
               C+ +
Sbjct  520  GRNCQDI  526


 Score = 70.1 bits (170),  Expect = 7e-12, Method: Compositional matrix adjust.
 Identities = 61/191 (31%), Positives = 87/191 (45%), Gaps = 22/191 (11%)

Query  44   CQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTC-------GCGPYRQE  96
            C+ GF    +     CIDI+EC      C   G  C+N  GS+TC       G G +  E
Sbjct  294  CKSGFIQDALG---NCIDINECLSISAPCP-IGHTCINTEGSYTCQKNVPNCGRGYHLNE  349

Query  97   KDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNEN  156
            +   C+D++EC+     C +   C+N  G  + C+C  G+    D  +  C D+NEC   
Sbjct  350  EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR-CECKTGYYF--DGISRMCVDVNECQRY  406

Query  157  P-SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPG  215
            P  +C     C N  GSY C CS GF     G  C  ED      + C      C+ V G
Sbjct  407  PGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSC--EDINECSSSPCSQ---ECANVYG  459

Query  216  SFKCECIQGFR  226
            S++C C +G++
Sbjct  460  SYQCYCRRGYQ  470


 Score = 69.3 bits (168),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 61/192 (31%), Positives = 83/192 (43%), Gaps = 18/192 (9%)

Query  57   STCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDGV-------CIDINECST  109
            ++C DIDEC  G+ NC      C N  GSF C   P  Q K G        CIDINEC +
Sbjct  258  NSCKDIDECESGIHNCL-PDFICQNTLGSFRCR--PKLQCKSGFIQDALGNCIDINECLS  314

Query  110  NRGNCDENSDCINLDG----EEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSV  165
                C     CIN +G    ++ +  C +G+  N +     C D++EC      C     
Sbjct  315  ISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEE--GTRCVDVDECAPPAEPCGKGHR  372

Query  166  CTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGF  225
            C N  GS++CEC  G+  D     CV  + C   +         C    GS+ C C  GF
Sbjct  373  CVNSPGSFRCECKTGYYFDGISRMCVDVNEC--QRYPGRLCGHKCENTLGSYLCSCSVGF  430

Query  226  RGAGTVNTCEPL  237
            R +    +CE +
Sbjct  431  RLSVDGRSCEDI  442


> Hs8393299
Length=443

 Score = 85.1 bits (209),  Expect = 2e-16, Method: Compositional matrix adjust.
 Identities = 62/188 (32%), Positives = 88/188 (46%), Gaps = 19/188 (10%)

Query  44   CQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDGVCID  103
            C  G+ P       +C+D+DECAQ L +C+    DC N+PGS+ C C    ++    C+D
Sbjct  109  CPPGYEPDD---QDSCVDVDECAQALHDCR-PSQDCHNLPGSYQCTCPDGYRKIGPECVD  164

Query  104  INECSTNRGNCDENSDCINLDGEEQLCKCHKGWT-GNNDKPNVACRDINECNENPSICPS  162
            I+EC      C     C+NL G  + C+C  G+  G N++   +C D+NEC+      P 
Sbjct  165  IDECRYRY--CQHR--CVNLPGSFR-CQCEPGFQLGPNNR---SCVDVNECDMG---APC  213

Query  163  NSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECI  222
               C N  G++ C C  G+E    G  C   D C      C      C   PG F C C 
Sbjct  214  EQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQY---RCVNEPGRFSCHCP  270

Query  223  QGFRGAGT  230
            QG++   T
Sbjct  271  QGYQLLAT  278


 Score = 57.4 bits (137),  Expect = 4e-08, Method: Compositional matrix adjust.
 Identities = 56/198 (28%), Positives = 80/198 (40%), Gaps = 42/198 (21%)

Query  56   SSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTC---------------------------  88
            S  C D++EC    + CK +   C+N  G + C                           
Sbjct  49   SQHCRDVNECLTIPEACKGEM-KCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPN  107

Query  89   GCGP-YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVAC  147
             C P Y  +    C+D++EC+    +C  + DC NL G  Q C C  G+     K    C
Sbjct  108  PCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQ-CTCPDGYR----KIGPEC  162

Query  148  RDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVF  207
             DI+EC      C     C NL GS++C+C  GF+   +   CV  + C  G   C+   
Sbjct  163  VDIDECRYR--YC--QHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGA-PCEQ--  215

Query  208  AACSLVPGSFKCECIQGF  225
              C    G+F C C QG+
Sbjct  216  -RCFNSYGTFLCRCHQGY  232


 Score = 57.4 bits (137),  Expect = 4e-08, Method: Compositional matrix adjust.
 Identities = 47/138 (34%), Positives = 64/138 (46%), Gaps = 14/138 (10%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
            F C C+ GF     N S  C+D++EC  G   C+Q+   C N  G+F C C   Y   +D
Sbjct  184  FRCQCEPGFQLGPNNRS--CVDVNECDMGAP-CEQR---CFNSYGTFLCRCHQGYELHRD  237

Query  99   GV-CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP  157
            G  C DI+ECS +   C     C+N  G    C C +G+     +    C+DI+EC    
Sbjct  238  GFSCSDIDECSYSSYLCQYR--CVNEPGRFS-CHCPQGYQLLATR---LCQDIDECESGA  291

Query  158  SICPSNSVCTNLAGSYKC  175
              C     C N  G Y+C
Sbjct  292  HQCSEAQTCVNFHGGYRC  309


 Score = 46.6 bits (109),  Expect = 7e-05, Method: Compositional matrix adjust.
 Identities = 37/126 (29%), Positives = 48/126 (38%), Gaps = 31/126 (24%)

Query  131  KCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKC---------------  175
            +C  G+  + D  +  CRD+NEC   P  C     C N  G Y C               
Sbjct  38   ECTDGYEWDPDSQH--CRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEG  95

Query  176  ------------ECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQ  223
                         C  G+EPD   S CV  D C    +DC      C  +PGS++C C  
Sbjct  96   PPPPVPPAQHPNPCPPGYEPDDQDS-CVDVDECAQALHDCRPS-QDCHNLPGSYQCTCPD  153

Query  224  GFRGAG  229
            G+R  G
Sbjct  154  GYRKIG  159


 Score = 44.3 bits (103),  Expect = 4e-04, Method: Compositional matrix adjust.
 Identities = 44/160 (27%), Positives = 61/160 (38%), Gaps = 36/160 (22%)

Query  101  CIDINECSTNRGNCDENSDCIN-----------------LDGE---------EQLCKCHK  134
            C D+NEC T    C     CIN                 L GE         +    C  
Sbjct  52   CRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNPCPP  111

Query  135  GWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTED  194
            G+  ++     +C D++EC +    C  +  C NL GSY+C C  G+     G  CV  D
Sbjct  112  GYEPDDQD---SCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYR--KIGPECVDID  166

Query  195  FCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTC  234
             C             C  +PGSF+C+C  GF+      +C
Sbjct  167  ECRYRYCQ-----HRCVNLPGSFRCQCEPGFQLGPNNRSC  201


>
Length=447

 Score = 85.1 bits (209),  Expect = 2e-16, Method: Compositional matrix adjust.
 Identities = 61/185 (32%), Positives = 86/185 (46%), Gaps = 11/185 (5%)

Query  57   STCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDGV-----CIDINECSTNR  111
             +CIDIDEC  G  NC ++   C N  G F C C    + K  +     C+D NEC+  +
Sbjct  108  KSCIDIDECDTGEHNCGERQ-ICRNRNGGFVCSCPIGHELKRSIGGASTCVDTNECALEQ  166

Query  112  GNCDENSDCINLDGEEQLCKCHKGWTGNNDKPN-VACRDINECNENPSICPSNSVCTNLA  170
              C  N+ C N  G    C+C  G+   +D  N   C DI+EC   P +C     C N  
Sbjct  167  RVCPLNAQCFNTIGA-YYCECKAGFQKKSDGNNSTQCFDIDECQVIPGLCQQK--CLNFW  223

Query  171  GSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGT  230
            G Y+C C++G++       C   + C   K D       C   PGS++C C +G+  A  
Sbjct  224  GGYRCTCNSGYQLGPDNRTCNDINECEVHK-DYKLCMGLCINTPGSYQCSCPRGYILAAD  282

Query  231  VNTCE  235
            +NTC 
Sbjct  283  MNTCR  287


 Score = 70.5 bits (171),  Expect = 5e-12, Method: Compositional matrix adjust.
 Identities = 71/222 (31%), Positives = 90/222 (40%), Gaps = 23/222 (10%)

Query  30   HAESCQSGDGF----WCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGS  85
            H E  Q+ D         C  GF     N    CID +EC +   N       C+N  G 
Sbjct  34   HPEYSQNNDSISTNRRVDCSPGFYR---NTLGACIDTNECME--QNPCGNHERCINTNGH  88

Query  86   FTC----GCGP-YRQEKDG-VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGN  139
            F C     C P Y+   DG  CIDI+EC T   NC E   C N +G   +C C  G    
Sbjct  89   FRCESLLQCSPGYKSTVDGKSCIDIDECDTGEHNCGERQICRNRNGGF-VCSCPIGHELK  147

Query  140  NDKPNVA-CRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSG---CVTEDF  195
                  + C D NEC     +CP N+ C N  G+Y CEC AGF+  S G+    C   D 
Sbjct  148  RSIGGASTCVDTNECALEQRVCPLNAQCFNTIGAYYCECKAGFQKKSDGNNSTQCFDIDE  207

Query  196  CGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCEPL  237
            C      C      C    G ++C C  G++      TC  +
Sbjct  208  CQVIPGLCQ---QKCLNFWGGYRCTCNSGYQLGPDNRTCNDI  246


 Score = 63.5 bits (153),  Expect = 6e-10, Method: Compositional matrix adjust.
 Identities = 59/187 (31%), Positives = 86/187 (45%), Gaps = 17/187 (9%)

Query  23   DHCSRVEH----AESCQSGDG-FWCACQKGF-TPQGINLSSTCIDIDECAQGLDNCKQKG  76
            D C   EH     + C++ +G F C+C  G    + I  +STC+D +ECA     C    
Sbjct  114  DECDTGEHNCGERQICRNRNGGFVCSCPIGHELKRSIGGASTCVDTNECALEQRVCPL-N  172

Query  77   GDCVNIPGSFTCGCGP-YRQEKDG----VCIDINECSTNRGNCDENSDCINLDGEEQLCK  131
              C N  G++ C C   ++++ DG     C DI+EC    G C +   C+N  G  + C 
Sbjct  173  AQCFNTIGAYYCECKAGFQKKSDGNNSTQCFDIDECQVIPGLCQQ--KCLNFWGGYR-CT  229

Query  132  CHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCV  191
            C+ G+    D  N  C DINEC  +        +C N  GSY+C C  G+   +  + C 
Sbjct  230  CNSGYQLGPD--NRTCNDINECEVHKDYKLCMGLCINTPGSYQCSCPRGYILAADMNTCR  287

Query  192  TEDFCGT  198
              D C T
Sbjct  288  DVDECAT  294


 Score = 52.8 bits (125),  Expect = 9e-07, Method: Compositional matrix adjust.
 Identities = 54/184 (29%), Positives = 74/184 (40%), Gaps = 44/184 (23%)

Query  39   GFWCACQKGFTPQGI-NLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQ--  95
             ++C C+ GF  +   N S+ C DIDEC      C+QK   C+N  G + C C    Q  
Sbjct  181  AYYCECKAGFQKKSDGNNSTQCFDIDECQVIPGLCQQK---CLNFWGGYRCTCNSGYQLG  237

Query  96   EKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNE  155
              +  C DINEC  ++        CIN  G  Q C C +G+    D     CRD++EC  
Sbjct  238  PDNRTCNDINECEVHKDYKLCMGLCINTPGSYQ-CSCPRGYILAADMN--TCRDVDECAT  294

Query  156  NP--SIC------------------------------PSNSVCTNLAGSYKC---ECSAG  180
            +    +C                                N +CTN+ GSYKC    C  G
Sbjct  295  DSINQVCTGRVSIYCGFMYREQTKYINKFLTRKFTYNKKNDICTNIRGSYKCTTVNCPLG  354

Query  181  FEPD  184
            +  D
Sbjct  355  YSID  358


>
Length=3680

 Score = 84.3 bits (207),  Expect = 3e-16, Method: Compositional matrix adjust.
 Identities = 70/194 (36%), Positives = 101/194 (52%), Gaps = 33/194 (17%)

Query  61   DIDEC------AQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKDGVCIDINECSTNRGN  113
            DIDEC      A+ ++N      +C N+P  F C C   Y  + + +C D++EC  N  N
Sbjct  4    DIDECQDPAIAARCVEN-----AECCNLPAHFLCKCKDGYEGDGEVLCTDVDECR-NPEN  57

Query  114  CDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSY  173
            C  N+ C N  G    C C  G+ GNN      C+D++EC+  P++C   ++CTNL GSY
Sbjct  58   CGPNALCTNTPGN-YTCSCPDGYVGNNPY-REGCQDVDECSY-PNVCGPGAICTNLEGSY  114

Query  174  KCECSAGFEPD-SSGSGCVTEDFCGT---GKNDCDTVFAACSLVPGSFKCECIQGFRGAG  229
            +C+C  G++ D  S SGCV +D C     G+N      A C    GSF+C C  G+ G  
Sbjct  115  RCDCPPGYDGDGRSESGCVDQDECARTPCGRN------ADCLNTDGSFRCLCPDGYSG--  166

Query  230  TVNTCEPLPGNEDL  243
                 +P+ G ED+
Sbjct  167  -----DPMNGCEDV  175


 Score = 74.3 bits (181),  Expect = 3e-13, Method: Compositional matrix adjust.
 Identities = 73/205 (35%), Positives = 99/205 (48%), Gaps = 24/205 (11%)

Query  28   VEHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFT  87
            VE+AE C     F C C+ G+   G  L   C D+DEC +  +NC      C N PG++T
Sbjct  18   VENAECCNLPAHFLCKCKDGYEGDGEVL---CTDVDEC-RNPENCG-PNALCTNTPGNYT  72

Query  88   CGC-------GPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNN  140
            C C        PYR+     C D++ECS     C   + C NL+G  + C C  G+ G+ 
Sbjct  73   CSCPDGYVGNNPYREG----CQDVDECSYPN-VCGPGAICTNLEGSYR-CDCPPGYDGDG  126

Query  141  DKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGK  200
             +    C D +EC   P  C  N+ C N  GS++C C  G+  D   +GC   D C T  
Sbjct  127  -RSESGCVDQDECARTP--CGRNADCLNTDGSFRCLCPDGYSGDPM-NGCEDVDECAT-N  181

Query  201  NDCDTVFAACSLVPGSFKCECIQGF  225
            N C  + A C  + GSF+C C  GF
Sbjct  182  NPC-GLGAECVNLGGSFQCRCPSGF  205


 Score = 70.9 bits (172),  Expect = 4e-12, Method: Compositional matrix adjust.
 Identities = 76/251 (30%), Positives = 110/251 (43%), Gaps = 56/251 (22%)

Query  40   FWCACQKGFTPQGIN-LSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQ---  95
            + C+C  G+   G N     C D+DEC+    N    G  C N+ GS+ C C P      
Sbjct  71   YTCSCPDGYV--GNNPYREGCQDVDECS--YPNVCGPGAICTNLEGSYRCDCPPGYDGDG  126

Query  96   EKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNE  155
              +  C+D +EC+  R  C  N+DC+N DG  + C C  G++G+   P   C D++EC  
Sbjct  127  RSESGCVDQDECA--RTPCGRNADCLNTDGSFR-CLCPDGYSGD---PMNGCEDVDECAT  180

Query  156  NPSICPSNSVCTNLAGSYKCECSAGF----EPDS--------------------------  185
            N + C   + C NL GS++C C +GF    +P +                          
Sbjct  181  N-NPCGLGAECVNLGGSFQCRCPSGFVLEHDPHADQLPQPLNTQQLGYGPGATDIAPYQR  239

Query  186  ---SGSGCVTEDFCGT--GKNDCDTVFAACSLVPGSFKCECIQGFRGAG-----TVNTCE  235
               +G  C+  D C    G   C T  A C   PGS++C C  GF+G G      +N C+
Sbjct  240  TSGAGLACLDIDECNQPDGVAKCGT-NAKCINFPGSYRCLCPSGFQGQGYLHCENINECQ  298

Query  236  PLPGNEDLACT  246
              P  E+  CT
Sbjct  299  DNPCGENAICT  309


 Score = 69.7 bits (169),  Expect = 9e-12, Method: Compositional matrix adjust.
 Identities = 63/192 (32%), Positives = 85/192 (44%), Gaps = 43/192 (22%)

Query  36   SGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGS-FTCGC-GPY  93
            S  GF CAC  GF+    +  S C+D+DEC  G   C   G +CVN+PG  +TC C G  
Sbjct  523  SAGGFTCACPPGFS---GDPHSKCVDVDECRTGASKCG-AGAECVNVPGGGYTCRCPGNT  578

Query  94   RQEKDGV--CIDINECSTNRG-------------------------------NCDENSDC  120
              + D    C+ I  CS N                                 NC  ++ C
Sbjct  579  IADPDPSVRCVPIVSCSANEDCPGNSICDATKRCLCPEPNIGNDCRHPCEALNCGAHAQC  638

Query  121  INLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAG  180
            +  +G+ Q C C  G+TGN+      C DI+EC  NP  C   ++C+N AG Y C+C  G
Sbjct  639  MLANGQAQ-CLCAPGYTGNSALAG-GCNDIDECRANP--CAEKAICSNTAGGYLCQCPGG  694

Query  181  FEPDSSGSGCVT  192
               D    GC+T
Sbjct  695  SSGDPYREGCIT  706


 Score = 68.2 bits (165),  Expect = 3e-11, Method: Compositional matrix adjust.
 Identities = 81/233 (34%), Positives = 106/233 (45%), Gaps = 35/233 (15%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
            + C C  GF  QG      C +I+EC    DN   +   C +  GSF C C P Y  +  
Sbjct  275  YRCLCPSGFQGQGY---LHCENINECQ---DNPCGENAICTDTVGSFVCTCKPDYTGDPF  328

Query  99   GVCIDINECSTNRGNCDENSDCIN-LDGEEQLCKCHKGWTGNNDKPNVACR--DINECNE  155
              C+DI+EC+     C +++ C N + G    CKC +G+ G  D P VAC   D+N    
Sbjct  329  RGCVDIDECTALDKPCGQHAVCENTVPGYN--CKCPQGYDGKPD-PKVACEQVDVN----  381

Query  156  NPSICPSNSVCTNLAGSY--KCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLV  213
               +C SN  CTN A     +C C  GFEP   GS CV  D C T    C    A C   
Sbjct  382  --ILCSSNFDCTNNAECIENQCFCLDGFEP--IGSSCVDIDECRTHAEVCGP-HAQCLNT  436

Query  214  PGSFKCECIQGFRGAGTVNTC-EPLPGNEDLACTTLGLTCGDYKYCTKSTTQA  265
            PGS+ CEC  G+ G+     C +P    ED       + CG + YC     +A
Sbjct  437  PGSYGCECEAGYVGSPPRMACKQPC---ED-------VRCGAHAYCKPDQNEA  479


 Score = 65.5 bits (158),  Expect = 2e-10, Method: Compositional matrix adjust.
 Identities = 66/232 (28%), Positives = 103/232 (44%), Gaps = 35/232 (15%)

Query  3    PPRLAAMGGKSSTPCDAGGYDHCSRVEHAESCQSGDGFWCACQKGFTPQGINLSSTCIDI  62
            PPR+A         C A  Y    + +  E+       +C C+ G+T    ++++ C+DI
Sbjct  452  PPRMACKQPCEDVRCGAHAY---CKPDQNEA-------YCVCEDGWTYNPSDVAAGCVDI  501

Query  63   DEC--AQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKDGVCIDINECSTNRGNCDENSD  119
            DEC    G      +   C N  G FTC C P +  +    C+D++EC T    C   ++
Sbjct  502  DECDVMHGPFGSCGQNATCTNSAGGFTCACPPGFSGDPHSKCVDVDECRTGASKCGAGAE  561

Query  120  CINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSA  179
            C+N+ G    C+C  G T  +  P+V C  I  C+ N   CP NS+C     + +C C  
Sbjct  562  CVNVPGGGYTCRC-PGNTIADPDPSVRCVPIVSCSAN-EDCPGNSICD---ATKRCLCP-  615

Query  180  GFEPDSSGSGCVTEDFCGTGKNDCDTV----FAACSLVPGSFKCECIQGFRG  227
              EP+  G+ C         ++ C+ +     A C L  G  +C C  G+ G
Sbjct  616  --EPN-IGNDC---------RHPCEALNCGAHAQCMLANGQAQCLCAPGYTG  655


 Score = 64.7 bits (156),  Expect = 2e-10, Method: Compositional matrix adjust.
 Identities = 76/259 (29%), Positives = 110/259 (42%), Gaps = 54/259 (20%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
            + C C  G+   G +  S C+D DECA+       +  DC+N  GSF C C   Y  +  
Sbjct  114  YRCDCPPGYDGDGRS-ESGCVDQDECARTPCG---RNADCLNTDGSFRCLCPDGYSGDPM  169

Query  99   GVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDK----------------  142
              C D++EC+TN   C   ++C+NL G  Q C+C  G+   +D                 
Sbjct  170  NGCEDVDECATNN-PCGLGAECVNLGGSFQ-CRCPSGFVLEHDPHADQLPQPLNTQQLGY  227

Query  143  ---------------PNVACRDINECNENPSI--CPSNSVCTNLAGSYKCECSAGFEPDS  185
                             +AC DI+ECN+   +  C +N+ C N  GSY+C C +GF+   
Sbjct  228  GPGATDIAPYQRTSGAGLACLDIDECNQPDGVAKCGTNAKCINFPGSYRCLCPSGFQ---  284

Query  186  SGSGCVT-EDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCEPLPGNEDL-  243
             G G +  E+      N C    A C+   GSF C C   + G       +P  G  D+ 
Sbjct  285  -GQGYLHCENINECQDNPCGE-NAICTDTVGSFVCTCKPDYTG-------DPFRGCVDID  335

Query  244  ACTTLGLTCGDYKYCTKST  262
             CT L   CG +  C  + 
Sbjct  336  ECTALDKPCGQHAVCENTV  354


 Score = 52.4 bits (124),  Expect = 1e-06, Method: Compositional matrix adjust.
 Identities = 68/219 (31%), Positives = 95/219 (43%), Gaps = 41/219 (18%)

Query  39   GFWCACQKGFT----PQGINLSST--CIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--  90
            G+ C C  G +     +G   S T  C D + CA G + C Q      +  G+  C C  
Sbjct  686  GYLCQCPGGSSGDPYREGCITSKTVGCSDANPCATG-ETCVQD-----SYTGNSVCICRQ  739

Query  91   GPYRQEKDGVCIDINECSTNRGN--CDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACR  148
            G  R  ++G C D++ECS  RG   C  N+ C NL G  + C+C +G  GN   P + C 
Sbjct  740  GYERNSENGQCQDVDECSVQRGKPACGLNALCKNLPGSYE-CRCPQGHNGN---PFIMCE  795

Query  149  DIN--ECN-ENP----------------SICPSNSVCTNLAGSYK-CECSAGFEPDSSGS  188
              N  EC  ++P                  CPS + C ++AG    C C  G++    GS
Sbjct  796  ICNTPECQCQSPYKLVGNSCVLSGCSSGQACPSGAECISIAGGVSYCACPKGYQTQPDGS  855

Query  189  GCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRG  227
             CV  D C           A C   PGS+ C C +G++G
Sbjct  856  -CVDVDECEERGAQLCAFGAQCVNKPGSYSCHCPEGYQG  893


 Score = 52.4 bits (124),  Expect = 1e-06, Method: Compositional matrix adjust.
 Identities = 58/206 (28%), Positives = 85/206 (41%), Gaps = 49/206 (23%)

Query  36    SGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPY  93
             +G   +CAC KG+  Q      +C+D+DEC +        G  CVN PGS++C C  G  
Sbjct  836   AGGVSYCACPKGYQTQ---PDGSCVDVDECEERGAQLCAFGAQCVNKPGSYSCHCPEGYQ  892

Query  94    RQEKDGVC-IDINECSTNRGNCDENSDCIN-----------LDGEEQ-------------  128
                 +G+C +   +C+ +R  C  N  CI            LD ++              
Sbjct  893   GDAYNGLCALAQRKCAADR-ECAANEKCIQPGECVCPPPYFLDPQDNNKCKSPCERFPCG  951

Query  129   -----------LCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCEC  177
                         C C  G+ G+   P + C D +EC+  P  C   + C N  G Y+C C
Sbjct  952   INAKCTPSDPPQCMCEAGFKGD---PLLGCTDEDECSHLP--CAYGAYCVNKKGGYQCVC  1006

Query  178   SAGFEPDSSGSGCVTEDFCGTGKNDC  203
                +  D   SGC+ E   GT K+ C
Sbjct  1007  PKDYTGDPYKSGCIFES--GTPKSKC  1030


 Score = 48.5 bits (114),  Expect = 2e-05, Method: Compositional matrix adjust.
 Identities = 56/190 (29%), Positives = 86/190 (45%), Gaps = 28/190 (14%)

Query  30   HAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCG  89
            HA+   +     C C  G+T     L+  C DIDEC    + C +K   C N  G + C 
Sbjct  635  HAQCMLANGQAQCLCAPGYTGNSA-LAGGCNDIDECR--ANPCAEKA-ICSNTAGGYLCQ  690

Query  90   C------GPYRQ----EKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGN  139
            C       PYR+     K   C D N C+T    C ++S   N      +C C +G+  N
Sbjct  691  CPGGSSGDPYREGCITSKTVGCSDANPCATGE-TCVQDSYTGN-----SVCICRQGYERN  744

Query  140  NDKPNVACRDINECN--ENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCG  197
            ++  N  C+D++EC+       C  N++C NL GSY+C C  G     +G+  +  + C 
Sbjct  745  SE--NGQCQDVDECSVQRGKPACGLNALCKNLPGSYECRCPQGH----NGNPFIMCEICN  798

Query  198  TGKNDCDTVF  207
            T +  C + +
Sbjct  799  TPECQCQSPY  808


 Score = 47.4 bits (111),  Expect = 4e-05, Method: Compositional matrix adjust.
 Identities = 47/170 (27%), Positives = 77/170 (45%), Gaps = 35/170 (20%)

Query  42   CACQKGFTPQGINLSSTCIDIDECA--QGLDNCKQKGGDCVNIPGSFTCGC---------  90
            C C++G+     N    C D+DEC+  +G   C      C N+PGS+ C C         
Sbjct  735  CICRQGYERNSEN--GQCQDVDECSVQRGKPACGLNA-LCKNLPGSYECRCPQGHNGNPF  791

Query  91   --------------GPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGW  136
                           PY+   +  C+ ++ CS+ +  C   ++CI++ G    C C KG+
Sbjct  792  IMCEICNTPECQCQSPYKLVGNS-CV-LSGCSSGQA-CPSGAECISIAGGVSYCACPKGY  848

Query  137  TGNNDKPNVACRDINECNEN-PSICPSNSVCTNLAGSYKCECSAGFEPDS  185
                 +P+ +C D++EC E    +C   + C N  GSY C C  G++ D+
Sbjct  849  ---QTQPDGSCVDVDECEERGAQLCAFGAQCVNKPGSYSCHCPEGYQGDA  895


 Score = 45.1 bits (105),  Expect = 2e-04, Method: Compositional matrix adjust.
 Identities = 38/107 (35%), Positives = 51/107 (47%), Gaps = 8/107 (7%)

Query  114   CDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSY  173
             C EN+ C   +  +Q+C C  G++G+   P V C  I+ C + P  C   + C N  GSY
Sbjct  2535  CGENALCTT-EHHQQVCHCQPGFSGD---PRVRCDVIDFCRDAP--CGPGARCRNARGSY  2588

Query  174   KCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCE  220
             KC C  G   D    GC +   C T + DC    AAC+   G  KC 
Sbjct  2589  KCTCPPGLVGDPYNEGCRSSVECETNE-DCPP-HAACTKTNGVAKCR  2633


 Score = 43.5 bits (101),  Expect = 7e-04, Method: Compositional matrix adjust.
 Identities = 35/109 (32%), Positives = 48/109 (44%), Gaps = 19/109 (17%)

Query  101   CIDINECSTNRGNCDENSDCI-------------NLDGEEQLCKCHKGWTGNNDKPNVAC  147
             CID  +C+ +R    E + CI              +   +  C C++G+   ND     C
Sbjct  2152  CIDHVDCAGDRACDAETNRCIKPCDLTSCGKGNCQVRDHKATCACYEGYQLVND----VC  2207

Query  148   RDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFC  196
              DINEC   P  C S + C NL GSY C+C  G   D   +GC   + C
Sbjct  2208  EDINECLSQP--CHSTAFCNNLPGSYSCQCPEGLIGDPLQAGCRDPNEC  2254


 Score = 38.1 bits (87),  Expect = 0.028, Method: Compositional matrix adjust.
 Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 8/77 (10%)

Query  105   NECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNS  164
             N C  N  +C  N++C  + G    C C +G++GN   P + C+D++EC   P  C  N+
Sbjct  1231  NVCQPN--SCGPNAECRAV-GNHISCLCPQGFSGN---PYIGCQDVDECANKP--CGLNA  1282

Query  165   VCTNLAGSYKCECSAGF  181
              C N AG ++C C +G 
Sbjct  1283  ACLNRAGGFECLCLSGH  1299


> CE25695_1
Length=2353

 Score = 83.6 bits (205),  Expect = 6e-16, Method: Compositional matrix adjust.
 Identities = 71/226 (31%), Positives = 104/226 (46%), Gaps = 17/226 (7%)

Query  16    PCDA--GGYDHCSRVEHAESCQSGDG-FWCA-CQKGFTPQGINLSSTCIDIDECAQGLDN  71
             PCD+      HCS    +    + DG   C  C  G+   G      C DI+EC      
Sbjct  1539  PCDSTQSSKSHCSESNMSCEVDTVDGSVECKECMGGYKKSG----KVCEDINECVAEKAP  1594

Query  72    CKQKGGDCVNIPGSFTCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCK  131
             C     +CVN+ G+F+C C    +    +C DINEC   R  C  +++C NL+G  + C+
Sbjct  1595  CSLNA-NCVNMNGTFSCSCKQGYRGDGFMCTDINECD-ERHPCHPHAECTNLEGSFK-CE  1651

Query  132   CHKGWTGNNDKP-----NVACRDINE-CNENPSICPSNSVCTNLAGSYKCECSAGFEPDS  185
             CH G+ G+  K        +C D+ + C     +   +    N + S  CEC  GF  + 
Sbjct  1652  CHSGFEGDGIKKCTNPLERSCEDVEKFCGRVDHVSCLSVRIYNGSLSSVCECEPGFRFEK  1711

Query  186   SGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTV  231
               + CV  D C   +N+CD   A C    GS++CEC +G+ G G V
Sbjct  1712  ESNSCVDIDECEESRNNCDPASAVCVNTEGSYRCECAEGYEGEGGV  1757


 Score = 83.2 bits (204),  Expect = 7e-16, Method: Compositional matrix adjust.
 Identities = 72/249 (28%), Positives = 98/249 (39%), Gaps = 66/249 (26%)

Query  42    CACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKDGV  100
             C C+ GF  +G     +C+D+DECA G  NC +    C N  G + C C   +R+  DG 
Sbjct  1433  CRCEPGF--EGAPPKKSCVDVDECATGDHNCHES-ARCQNYVGGYACFCPTGFRKADDGS  1489

Query  101   CIDINECSTNRGN-CDENSDCINLDGEEQLCKCHKGWTGNN-------------------  140
             C DI+EC+ +    C  N+ C+N  G    C+C  G+ G+                    
Sbjct  1490  CQDIDECTEHNSTCCGANAKCVNKPGTYS-CECENGFLGDGYQCVPTTKKPCDSTQSSKS  1548

Query  141   ---------------------------DKPNVACRDINECNENPSICPSNSVCTNLAGSY  173
                                         K    C DINEC    + C  N+ C N+ G++
Sbjct  1549  HCSESNMSCEVDTVDGSVECKECMGGYKKSGKVCEDINECVAEKAPCSLNANCVNMNGTF  1608

Query  174   KCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTV-----FAACSLVPGSFKCECIQGFRGA  228
              C C  G+  D          F  T  N+CD        A C+ + GSFKCEC  GF G 
Sbjct  1609  SCSCKQGYRGDG---------FMCTDINECDERHPCHPHAECTNLEGSFKCECHSGFEGD  1659

Query  229   GTVNTCEPL  237
             G      PL
Sbjct  1660  GIKKCTNPL  1668


 Score = 73.2 bits (178),  Expect = 8e-13, Method: Compositional matrix adjust.
 Identities = 103/370 (27%), Positives = 143/370 (38%), Gaps = 92/370 (24%)

Query  29   EHAESCQSGDGFWCACQKGFTPQGINLS--STCIDIDECAQGLDNCKQKGGDCVNIPGSF  86
            EH++       ++C C +GFTP+G   S    C DI+EC  G  NC      C N  GSF
Sbjct  174  EHSKCINLPGTYYCNCTQGFTPKGNQGSGLDKCADINECETGAHNCDADE-ICENSIGSF  232

Query  87   TC--GCGPYRQEKDGVCIDINECSTNR-GNCDENSDCINL--------------DGEE--  127
             C   C P  +  DG C D+NEC + +   CD  +DC+N               DG+   
Sbjct  233  KCVNKCSPGYELIDGKCEDVNECGSEKLHKCDVRADCVNTIGGYECECEEGFEGDGKNCQ  292

Query  128  --------------------------------QLCKCHKGWTGNNDKPNVACRDINECNE  155
                                             +C C  G+TG+     + C DINEC+ 
Sbjct  293  RKCGHSVKLPSKSSCRKNSAICDRHASCHIVLDICDCKTGYTGDG----ITCHDINECDA  348

Query  156  NPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTED--FCGTGKNDCDTVFAACSLV  213
              + C     C NL G Y C C  G +     + C+ +   FC  G  D     A CS  
Sbjct  349  KDTPCSDGGRCLNLDGGYVC-CKNGQD----DATCIKDQGAFCSGGCGD----NAICS--  397

Query  214  PGSFKCECIQGFRGAGT-----VNTCEPLPGNEDLACTTLGLTC----GDYKYCTKSTTQ  264
              +  C CI GFRG        +N C       D  C  +G  C    G +K C   +T+
Sbjct  398  --NATCACIDGFRGDPHKKCVDINECV----ENDSVCGGVGDRCVNLFGGFKCCQHGSTE  451

Query  265  AGLWECTDKAASEQLAVFIANGATSDTPSWVWAVVVLSTIALILISGGVLWCLYKRFIKT  324
            A   ECTD+A S   +   ++GA   T       ++  + ++   SGG +        K 
Sbjct  452  A---ECTDQAFSSDSSTISSHGADFTT---TGEQIIEGSGSIQTSSGGSITVTRGLIPKD  505

Query  325  REDTEEDLLA  334
             E T    LA
Sbjct  506  VELTTSGRLA  515


 Score = 66.6 bits (161),  Expect = 7e-11, Method: Compositional matrix adjust.
 Identities = 46/121 (38%), Positives = 62/121 (51%), Gaps = 10/121 (8%)

Query  25    CSRVEHAESCQSGDGF------WCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGD  78
             C RV+H  SC S   +       C C+ GF  +    S++C+DIDEC +  +NC      
Sbjct  1679  CGRVDHV-SCLSVRIYNGSLSSVCECEPGFRFE--KESNSCVDIDECEESRNNCDPASAV  1735

Query  79    CVNIPGSFTCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTG  138
             CVN  GS+ C C    + + GVC DI+EC      CD  + CIN  G    CKC  G+TG
Sbjct  1736  CVNTEGSYRCECAEGYEGEGGVCTDIDECDRGMAGCDSMAMCINRMG-SCGCKCMAGYTG  1794

Query  139   N  139
             +
Sbjct  1795  D  1795


 Score = 64.7 bits (156),  Expect = 2e-10, Method: Compositional matrix adjust.
 Identities = 64/186 (34%), Positives = 94/186 (50%), Gaps = 25/186 (13%)

Query  56    SSTCIDIDECAQGLDN-CKQKGGDCVNIPGSFTCGCGPYRQEKDGVCIDINECSTNRGNC  114
             ++ C   DEC  GLD  C+++ G C   PG    G  P +      C+D++EC+T   NC
Sbjct  1411  NTKCTSSDEC--GLDALCERRTGVCRCEPGFE--GAPPKKS-----CVDVDECATGDHNC  1461

Query  115   DENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNE-NPSICPSNSVCTNLAGSY  173
              E++ C N  G    C C  G+   +D    +C+DI+EC E N + C +N+ C N  G+Y
Sbjct  1462  HESARCQNYVG-GYACFCPTGFRKADDG---SCQDIDECTEHNSTCCGANAKCVNKPGTY  1517

Query  174   KCECSAGFEPDSSGSGCVTE-----DFCGTGKNDCDTVFAACSL--VPGSFKC-ECIQGF  225
              CEC  GF  D  G  CV       D   + K+ C     +C +  V GS +C EC+ G+
Sbjct  1518  SCECENGFLGD--GYQCVPTTKKPCDSTQSSKSHCSESNMSCEVDTVDGSVECKECMGGY  1575

Query  226   RGAGTV  231
             + +G V
Sbjct  1576  KKSGKV  1581


 Score = 57.0 bits (136),  Expect = 6e-08, Method: Compositional matrix adjust.
 Identities = 47/142 (33%), Positives = 66/142 (46%), Gaps = 16/142 (11%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC----GPYRQ  95
            + C C  G+   G      C DIDEC+  L +   +   C+N+PG++ C C     P   
Sbjct  143  YECRCLPGYEGNG----HECTDIDECSDKLTSRCPEHSKCINLPGTYYCNCTQGFTPKGN  198

Query  96   EKDGV--CIDINECSTNRGNCDENSDCINLDGEEQ-LCKCHKGWTGNNDKPNVACRDINE  152
            +  G+  C DINEC T   NCD +  C N  G  + + KC  G+   + K    C D+NE
Sbjct  199  QGSGLDKCADINECETGAHNCDADEICENSIGSFKCVNKCSPGYELIDGK----CEDVNE  254

Query  153  C-NENPSICPSNSVCTNLAGSY  173
            C +E    C   + C N  G Y
Sbjct  255  CGSEKLHKCDVRADCVNTIGGY  276


 Score = 43.1 bits (100),  Expect = 8e-04, Method: Compositional matrix adjust.
 Identities = 46/132 (34%), Positives = 65/132 (49%), Gaps = 18/132 (13%)

Query  98    DGV-CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVAC-RDINECNE  155
             DGV C+ I+E ++N   CD N+ C+        CKC+ G+ GN     + C  D  +C  
Sbjct  2134  DGVKCVSIHERASNCSQCDANAHCVG----GTTCKCNPGYFGN----GLCCVPDPLDCVH  2185

Query  156   NPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPG  215
                IC  N+VC   + S +C+CS+GF    +G  C  +  C T K+ C     A  L  G
Sbjct  2186  FTGICHPNAVCN--SESRQCQCSSGFS--GNGVSCFPQKSCRTDKSVC--AKNAICLPTG  2239

Query  216   SFKCECIQGFRG  227
             S  C C  GF+G
Sbjct  2240  S--CICRHGFKG  2249


 Score = 39.7 bits (91),  Expect = 0.008, Method: Compositional matrix adjust.
 Identities = 66/246 (26%), Positives = 86/246 (34%), Gaps = 69/246 (28%)

Query  42    CACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDGVC  101
             C C  GFT  G+     C+ I E A     C      CV   G  TC C P        C
Sbjct  2125  CQCLPGFTGDGVK----CVSIHERASNCSQCDANA-HCV---GGTTCKCNPGYFGNGLCC  2176

Query  102   I-DINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSIC  160
             + D  +C    G C  N+ C   + E + C+C  G++GN     V+C     C  + S+C
Sbjct  2177  VPDPLDCVHFTGICHPNAVC---NSESRQCQCSSGFSGNG----VSCFPQKSCRTDKSVC  2229

Query  161   PSNSVC-----------------------------------------------TNLAGSY  173
               N++C                                               T L  S 
Sbjct  2230  AKNAICLPTGSCICRHGFKGDPFYKCSSLVSKEPANQQDLSDVSSCVTPCDSSTQLCISG  2289

Query  174   KCECSAGFEPDSSGSG---CVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGT  230
             +C C +GF  +S+ SG   C   D C    + CD V A C    GS  C C  G  G G 
Sbjct  2290  ECICKSGFRRNSTLSGSETCADIDECAEKSHKCDRV-ATCRNTFGSHVCTCPDGHVGDGI  2348

Query  231   VNTCEP  236
               TC P
Sbjct  2349  --TCVP  2352


 Score = 30.8 bits (68),  Expect = 3.8, Method: Compositional matrix adjust.
 Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 5/74 (6%)

Query  38    DGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEK  97
             D  +C+C  GF   G+     C D+DEC      C  +   C N  GSF C C    ++ 
Sbjct  1879  DSHFCSCPDGFIGDGM----ICDDVDEC-NNAGMCDDENTKCENTIGSFNCVCLEGFKKV  1933

Query  98    DGVCIDINECSTNR  111
             D  C+   +   NR
Sbjct  1934  DEKCVVDEKKQPNR  1947


> CE26701
Length=712

 Score = 82.0 bits (201),  Expect = 2e-15, Method: Compositional matrix adjust.
 Identities = 69/190 (36%), Positives = 96/190 (50%), Gaps = 23/190 (12%)

Query  44   CQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTC-------GCGPYRQE  96
            C  G+ P+    +  C DIDEC  G  NC   G +CVN PGSF C         G     
Sbjct  291  CPNGYYPK----NGMCNDIDECVTG-HNCG-AGEECVNTPGSFRCQQKGNLCAHGYEVNG  344

Query  97   KDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNEN  156
              G C D+NEC   +G C  + +CINL G  + CKC  G+  N+ K    C D++EC + 
Sbjct  345  ATGFCEDVNECQ--QGVCG-SMECINLPGTYK-CKCGPGYEFNDAKKR--CEDVDECIKF  398

Query  157  P-SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPG  215
               +C  ++ C N  GS++C+C  GF+  S G  C   + C TG   C+     C  +PG
Sbjct  399  AGHVCDLSAECINTIGSFECKCKPGFQLASDGRRCEDVNECTTGIAACEQ---KCVNIPG  455

Query  216  SFKCECIQGF  225
            S++C C +GF
Sbjct  456  SYQCICDRGF  465


 Score = 78.2 bits (191),  Expect = 3e-14, Method: Compositional matrix adjust.
 Identities = 65/198 (32%), Positives = 96/198 (48%), Gaps = 21/198 (10%)

Query  44   CQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDG--VC  101
            C  G+   G   +  C D++EC QG+  C     +C+N+PG++ C CGP  +  D    C
Sbjct  336  CAHGYEVNGA--TGFCEDVNECQQGV--CGSM--ECINLPGTYKCKCGPGYEFNDAKKRC  389

Query  102  IDINECSTNRGN-CDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSIC  160
             D++EC    G+ CD +++CIN  G  + CKC  G+   +D     C D+NEC    + C
Sbjct  390  EDVDECIKFAGHVCDLSAECINTIGSFE-CKCKPGFQLASD--GRRCEDVNECTTGIAAC  446

Query  161  PSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFC----GTGKNDCDTVFAACSLVPGS  216
                 C N+ GSY+C C  GF     G+ C   D C    G+G + C      C    GS
Sbjct  447  EQK--CVNIPGSYQCICDRGFALGPDGTKCEDIDECSIWAGSGNDLC---MGGCINTKGS  501

Query  217  FKCECIQGFRGAGTVNTC  234
            + C+C  G++      TC
Sbjct  502  YLCQCPPGYKIQPDGRTC  519


 Score = 72.4 bits (176),  Expect = 1e-12, Method: Compositional matrix adjust.
 Identities = 61/189 (32%), Positives = 87/189 (46%), Gaps = 17/189 (8%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
            + C C  G+  +  +    C D+DEC +   +      +C+N  GSF C C P ++   D
Sbjct  372  YKCKCGPGY--EFNDAKKRCEDVDECIKFAGHVCDLSAECINTIGSFECKCKPGFQLASD  429

Query  99   GV-CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECN---  154
            G  C D+NEC+T    C++   C+N+ G  Q C C +G+    D     C DI+EC+   
Sbjct  430  GRRCEDVNECTTGIAACEQK--CVNIPGSYQ-CICDRGFALGPD--GTKCEDIDECSIWA  484

Query  155  -ENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLV  213
                 +C     C N  GSY C+C  G++    G  CV  D C  G  +C      C   
Sbjct  485  GSGNDLCMGG--CINTKGSYLCQCPPGYKIQPDGRTCVDVDECAMG--ECAGSDKVCVNT  540

Query  214  PGSFKCECI  222
             GSFKC  I
Sbjct  541  LGSFKCHSI  549


 Score = 67.0 bits (162),  Expect = 6e-11, Method: Compositional matrix adjust.
 Identities = 68/240 (28%), Positives = 103/240 (42%), Gaps = 41/240 (17%)

Query  26   SRVEHAESCQSGDGFWCACQKGF--TPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIP  83
            S  EH    + G+   C+C+ GF   P G+     C+DIDECA  +D+C +    C+N P
Sbjct  162  SHCEHLCHDRGGEKVECSCRSGFDLAPDGM----ACVDIDECATLMDDCLES-QRCLNTP  216

Query  84   GSF------TCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWT  137
            GSF      +CG G     +   C D++EC+    +C     C N  G  + C   K   
Sbjct  217  GSFKCIRTLSCGTGYAMDSETERCRDVDECNLGSHDCGPLYQCRNTQGSYR-CDAKKCGD  275

Query  138  GNNDKP-----------------NVACRDINECNENPSICPSNSVCTNLAGSYKCE----  176
            G    P                 N  C DI+EC    + C +   C N  GS++C+    
Sbjct  276  GELQNPMTGECTSITCPNGYYPKNGMCNDIDECVTGHN-CGAGEECVNTPGSFRCQQKGN  334

Query  177  -CSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCE  235
             C+ G+E + +   C   + C  G   C ++   C  +PG++KC+C  G+        CE
Sbjct  335  LCAHGYEVNGATGFCEDVNECQQGV--CGSM--ECINLPGTYKCKCGPGYEFNDAKKRCE  390


 Score = 44.3 bits (103),  Expect = 4e-04, Method: Compositional matrix adjust.
 Identities = 47/133 (35%), Positives = 62/133 (46%), Gaps = 29/133 (21%)

Query  40   FWCACQKGFT--PQGINLSSTCIDIDECA----QGLDNCKQKGGDCVNIPGSFTCGCGP-  92
            + C C +GF   P G    + C DIDEC+     G D C    G C+N  GS+ C C P 
Sbjct  457  YQCICDRGFALGPDG----TKCEDIDECSIWAGSGNDLCM---GGCINTKGSYLCQCPPG  509

Query  93   YRQEKDG-VCIDINECSTNRGNCD-ENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRD-  149
            Y+ + DG  C+D++EC+   G C   +  C+N  G     KCH     + D P     D 
Sbjct  510  YKIQPDGRTCVDVDECAM--GECAGSDKVCVNTLGSF---KCH-----SIDCPTNYIHDS  559

Query  150  --INECNENPSIC  160
               N CN  PS C
Sbjct  560  LNKNRCNRQPSAC  572


> CE26702
Length=689

 Score = 81.6 bits (200),  Expect = 2e-15, Method: Compositional matrix adjust.
 Identities = 69/190 (36%), Positives = 96/190 (50%), Gaps = 23/190 (12%)

Query  44   CQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTC-------GCGPYRQE  96
            C  G+ P+    +  C DIDEC  G  NC   G +CVN PGSF C         G     
Sbjct  291  CPNGYYPK----NGMCNDIDECVTG-HNCG-AGEECVNTPGSFRCQQKGNLCAHGYEVNG  344

Query  97   KDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNEN  156
              G C D+NEC   +G C  + +CINL G  + CKC  G+  N+ K    C D++EC + 
Sbjct  345  ATGFCEDVNEC--QQGVCG-SMECINLPGTYK-CKCGPGYEFNDAKKR--CEDVDECIKF  398

Query  157  P-SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPG  215
               +C  ++ C N  GS++C+C  GF+  S G  C   + C TG   C+     C  +PG
Sbjct  399  AGHVCDLSAECINTIGSFECKCKPGFQLASDGRRCEDVNECTTGIAACE---QKCVNIPG  455

Query  216  SFKCECIQGF  225
            S++C C +GF
Sbjct  456  SYQCICDRGF  465


 Score = 77.8 bits (190),  Expect = 3e-14, Method: Compositional matrix adjust.
 Identities = 63/190 (33%), Positives = 94/190 (49%), Gaps = 21/190 (11%)

Query  44   CQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDG--VC  101
            C  G+   G   +  C D++EC QG+  C     +C+N+PG++ C CGP  +  D    C
Sbjct  336  CAHGYEVNG--ATGFCEDVNECQQGV--CGSM--ECINLPGTYKCKCGPGYEFNDAKKRC  389

Query  102  IDINECSTNRGN-CDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSIC  160
             D++EC    G+ CD +++CIN  G  + CKC  G+   +D     C D+NEC    + C
Sbjct  390  EDVDECIKFAGHVCDLSAECINTIGSFE-CKCKPGFQLASDGRR--CEDVNECTTGIAAC  446

Query  161  PSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFC----GTGKNDCDTVFAACSLVPGS  216
                 C N+ GSY+C C  GF     G+ C   D C    G+G + C      C    GS
Sbjct  447  EQK--CVNIPGSYQCICDRGFALGPDGTKCEDIDECSIWAGSGNDLC---MGGCINTKGS  501

Query  217  FKCECIQGFR  226
            + C+C  G++
Sbjct  502  YLCQCPPGYK  511


 Score = 72.0 bits (175),  Expect = 2e-12, Method: Compositional matrix adjust.
 Identities = 61/189 (32%), Positives = 86/189 (45%), Gaps = 17/189 (8%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
            + C C  G+     +    C D+DEC +   +      +C+N  GSF C C P ++   D
Sbjct  372  YKCKCGPGYEFN--DAKKRCEDVDECIKFAGHVCDLSAECINTIGSFECKCKPGFQLASD  429

Query  99   GV-CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECN---  154
            G  C D+NEC+T    C++   C+N+ G  Q C C +G+    D     C DI+EC+   
Sbjct  430  GRRCEDVNECTTGIAACEQK--CVNIPGSYQ-CICDRGFALGPD--GTKCEDIDECSIWA  484

Query  155  -ENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLV  213
                 +C     C N  GSY C+C  G++    G  CV  D C  G  +C      C   
Sbjct  485  GSGNDLCMGG--CINTKGSYLCQCPPGYKIQPDGRTCVDVDECAMG--ECAGSDKVCVNT  540

Query  214  PGSFKCECI  222
             GSFKC  I
Sbjct  541  LGSFKCHSI  549


 Score = 66.6 bits (161),  Expect = 7e-11, Method: Compositional matrix adjust.
 Identities = 68/242 (28%), Positives = 104/242 (42%), Gaps = 41/242 (16%)

Query  26   SRVEHAESCQSGDGFWCACQKGF--TPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIP  83
            S  EH    + G+   C+C+ GF   P G+     C+DIDECA  +D+C +    C+N P
Sbjct  162  SHCEHLCHDRGGEKVECSCRSGFDLAPDGM----ACVDIDECATLMDDCLES-QRCLNTP  216

Query  84   GSF------TCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWT  137
            GSF      +CG G     +   C D++EC+    +C     C N  G  + C   K   
Sbjct  217  GSFKCIRTLSCGTGYAMDSETERCRDVDECNLGSHDCGPLYQCRNTQGSYR-CDAKKCGD  275

Query  138  GNNDKP-----------------NVACRDINECNENPSICPSNSVCTNLAGSYKCE----  176
            G    P                 N  C DI+EC    + C +   C N  GS++C+    
Sbjct  276  GELQNPMTGECTSITCPNGYYPKNGMCNDIDECVTGHN-CGAGEECVNTPGSFRCQQKGN  334

Query  177  -CSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCE  235
             C+ G+E + +   C   + C  G   C ++   C  +PG++KC+C  G+        CE
Sbjct  335  LCAHGYEVNGATGFCEDVNECQQGV--CGSM--ECINLPGTYKCKCGPGYEFNDAKKRCE  390

Query  236  PL  237
             +
Sbjct  391  DV  392


> Hs9665262
Length=493

 Score = 81.3 bits (199),  Expect = 3e-15, Method: Compositional matrix adjust.
 Identities = 65/184 (35%), Positives = 88/184 (47%), Gaps = 18/184 (9%)

Query  57   STCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDGVCIDINECSTNRGNCDE  116
            + C DIDEC  G  NC+     C+N+ GSF C C P  Q++   C+DI+EC T    C +
Sbjct  169  NVCQDIDECTAGTHNCR-ADQVCINLRGSFACQCPPGYQKRGEQCVDIDEC-TIPPYCHQ  226

Query  117  NSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCE  176
               C+N  G    C+C  G+    +  N  C DINEC+ + + C     C N+ GS+ C+
Sbjct  227  R--CVNTPGSF-YCQCSPGFQLAAN--NYTCVDINECDAS-NQCAQQ--CYNILGSFICQ  278

Query  177  CSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGF-----RGAGTV  231
            C+ G+E  S    C   D C T    C      C   PG F C C QG+     R    +
Sbjct  279  CNQGYELSSDRLNCEDIDECRTSSYLCQ---YQCVNEPGKFSCMCPQGYQVVRSRTCQDI  335

Query  232  NTCE  235
            N CE
Sbjct  336  NECE  339


 Score = 66.6 bits (161),  Expect = 6e-11, Method: Compositional matrix adjust.
 Identities = 53/169 (31%), Positives = 77/169 (45%), Gaps = 17/169 (10%)

Query  73   KQKGGDCVNIPGS----FTCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQ  128
            ++   D   IP +      C  G Y Q +  VC DI+EC+    NC  +  CINL G   
Sbjct  140  RRNPADPQRIPSNPSHRIQCAAG-YEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSF-  197

Query  129  LCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGS  188
             C+C  G+    ++    C DI+EC   P     +  C N  GS+ C+CS GF+  ++  
Sbjct  198  ACQCPPGYQKRGEQ----CVDIDECTIPPY---CHQRCVNTPGSFYCQCSPGFQLAANNY  250

Query  189  GCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCEPL  237
             CV  + C    N C      C  + GSF C+C QG+  +     CE +
Sbjct  251  TCVDINECD-ASNQCA---QQCYNILGSFICQCNQGYELSSDRLNCEDI  295


 Score = 60.5 bits (145),  Expect = 5e-09, Method: Compositional matrix adjust.
 Identities = 50/148 (33%), Positives = 68/148 (45%), Gaps = 15/148 (10%)

Query  30   HAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCG  89
            H     +   F+C C  GF     N   TC+DI+EC    D   Q    C NI GSF C 
Sbjct  225  HQRCVNTPGSFYCQCSPGFQLAANNY--TCVDINEC----DASNQCAQQCYNILGSFICQ  278

Query  90   CGP-YRQEKDGV-CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVAC  147
            C   Y    D + C DI+EC T+   C     C+N  G+   C C +G+     +    C
Sbjct  279  CNQGYELSSDRLNCEDIDECRTSSYLCQ--YQCVNEPGKFS-CMCPQGYQVVRSR---TC  332

Query  148  RDINECNENPSICPSNSVCTNLAGSYKC  175
            +DINEC E  + C  + +C N  G ++C
Sbjct  333  QDINEC-ETTNECREDEMCWNYHGGFRC  359


 Score = 47.0 bits (110),  Expect = 5e-05, Method: Compositional matrix adjust.
 Identities = 46/136 (33%), Positives = 59/136 (43%), Gaps = 21/136 (15%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
            F C C +G+      L+  C DIDEC      C+ +   CVN PG F+C C   Y+  + 
Sbjct  275  FICQCNQGYELSSDRLN--CEDIDECRTSSYLCQYQ---CVNEPGKFSCMCPQGYQVVRS  329

Query  99   GVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECN-ENP  157
              C DINEC T    C E+  C N  G            G    P   C+D      EN 
Sbjct  330  RTCQDINECETT-NECREDEMCWNYHG------------GFRCYPRNPCQDPYILTPENR  376

Query  158  SICP-SNSVCTNLAGS  172
             +CP SN++C  L  S
Sbjct  377  CVCPVSNAMCRELPQS  392


> Hs9665253
Length=470

 Score = 80.9 bits (198),  Expect = 4e-15, Method: Compositional matrix adjust.
 Identities = 65/184 (35%), Positives = 88/184 (47%), Gaps = 18/184 (9%)

Query  57   STCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDGVCIDINECSTNRGNCDE  116
            + C DIDEC  G  NC+     C+N+ GSF C C P  Q++   C+DI+EC T    C +
Sbjct  146  NVCQDIDECTAGTHNCR-ADQVCINLRGSFACQCPPGYQKRGEQCVDIDEC-TIPPYCHQ  203

Query  117  NSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCE  176
               C+N  G    C+C  G+    +  N  C DINEC+ + + C     C N+ GS+ C+
Sbjct  204  R--CVNTPGSF-YCQCSPGFQLAAN--NYTCVDINECDAS-NQCAQQ--CYNILGSFICQ  255

Query  177  CSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGF-----RGAGTV  231
            C+ G+E  S    C   D C T    C      C   PG F C C QG+     R    +
Sbjct  256  CNQGYELSSDRLNCEDIDECRTSSYLCQ---YQCVNEPGKFSCMCPQGYQVVRSRTCQDI  312

Query  232  NTCE  235
            N CE
Sbjct  313  NECE  316


 Score = 66.2 bits (160),  Expect = 8e-11, Method: Compositional matrix adjust.
 Identities = 48/145 (33%), Positives = 69/145 (47%), Gaps = 12/145 (8%)

Query  93   YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINE  152
            Y Q +  VC DI+EC+    NC  +  CINL G    C+C  G+    ++    C DI+E
Sbjct  140  YEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSF-ACQCPPGYQKRGEQ----CVDIDE  194

Query  153  CNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSL  212
            C   P     +  C N  GS+ C+CS GF+  ++   CV  + C    N C      C  
Sbjct  195  CTIPPY---CHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECD-ASNQCA---QQCYN  247

Query  213  VPGSFKCECIQGFRGAGTVNTCEPL  237
            + GSF C+C QG+  +     CE +
Sbjct  248  ILGSFICQCNQGYELSSDRLNCEDI  272


 Score = 59.7 bits (143),  Expect = 8e-09, Method: Compositional matrix adjust.
 Identities = 50/148 (33%), Positives = 68/148 (45%), Gaps = 15/148 (10%)

Query  30   HAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCG  89
            H     +   F+C C  GF     N   TC+DI+EC    D   Q    C NI GSF C 
Sbjct  202  HQRCVNTPGSFYCQCSPGFQLAANNY--TCVDINEC----DASNQCAQQCYNILGSFICQ  255

Query  90   CGP-YRQEKDGV-CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVAC  147
            C   Y    D + C DI+EC T+   C     C+N  G+   C C +G+     +    C
Sbjct  256  CNQGYELSSDRLNCEDIDECRTSSYLCQ--YQCVNEPGKFS-CMCPQGYQVVRSR---TC  309

Query  148  RDINECNENPSICPSNSVCTNLAGSYKC  175
            +DINEC E  + C  + +C N  G ++C
Sbjct  310  QDINEC-ETTNECREDEMCWNYHGGFRC  336


 Score = 47.0 bits (110),  Expect = 6e-05, Method: Compositional matrix adjust.
 Identities = 46/136 (33%), Positives = 59/136 (43%), Gaps = 21/136 (15%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
            F C C +G+      L+  C DIDEC      C+ +   CVN PG F+C C   Y+  + 
Sbjct  252  FICQCNQGYELSSDRLN--CEDIDECRTSSYLCQYQ---CVNEPGKFSCMCPQGYQVVRS  306

Query  99   GVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECN-ENP  157
              C DINEC T    C E+  C N  G            G    P   C+D      EN 
Sbjct  307  RTCQDINECETT-NECREDEMCWNYHG------------GFRCYPRNPCQDPYILTPENR  353

Query  158  SICP-SNSVCTNLAGS  172
             +CP SN++C  L  S
Sbjct  354  CVCPVSNAMCRELPQS  369


> Hs20536571
Length=5635

 Score = 80.5 bits (197),  Expect = 4e-15, Method: Compositional matrix adjust.
 Identities = 71/199 (35%), Positives = 87/199 (43%), Gaps = 18/199 (9%)

Query  44    CQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDGVCID  103
             C  GF      LS  C DI+EC +    C Q+   C N  GSF CGC P  Q K   C+D
Sbjct  5177  CGSGFRRTSDGLS--CQDINECQES-SPCHQR---CFNAIGSFHCGCEPGYQLKGRKCMD  5230

Query  104   INECSTNRGNCDENSDCINLDGEEQ-LCKCHKGWTGNNDKPNVACRDINECNENPSICPS  162
             +NEC  N   C  +  C N  G  + +  C  G T      N  C DI+EC +    C  
Sbjct  5231  VNECRQNV--CRPDQHCKNTRGGYKCIDLCPNGMTKAE---NGTCIDIDECKDGTHQCRY  5285

Query  163   NSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECI  222
             N +C N  GSY+C C  G+     G  C+  + C      C      CS  PGSFKC C 
Sbjct  5286  NQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCA---HQCSNTPGSFKCICP  5342

Query  223   QGFRGAGTVNTC---EPLP  238
              G    G   +C   E LP
Sbjct  5343  PGQHLLGDGKSCAGLERLP  5361


 Score = 60.8 bits (146),  Expect = 3e-09, Method: Compositional matrix adjust.
 Identities = 66/241 (27%), Positives = 93/241 (38%), Gaps = 62/241 (25%)

Query  50    PQGINLSST---CIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEKDGVCIDI  104
             P G  L S    C D DECA G + C      C N  G++ C C  G         C DI
Sbjct  5093  PSGFTLDSVGPFCADEDECAAG-NPCSH---SCHNAMGTYYCSCPKGLTIAADGRTCQDI  5148

Query  105   NECSTNRGNCDENSDCINLDGEEQ-LCKCHKGWTGNNDKPNVACRDINECNENPSICPSN  163
             +EC+  R  C    DC N  G  + + +C  G+   +D   ++C+DINEC E+    P +
Sbjct  5149  DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSD--GLSCQDINECQES---SPCH  5203

Query  164   SVCTNLAGSYKCECSAGFE------------------PD---------------------  184
               C N  GS+ C C  G++                  PD                     
Sbjct  5204  QRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMT  5263

Query  185   -SSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGT------VNTCEPL  237
              +    C+  D C  G + C      C    GS++C C +G+R  G       +N CE +
Sbjct  5264  KAENGTCIDIDECKDGTHQCR-YNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQV  5322

Query  238   P  238
             P
Sbjct  5323  P  5323


 Score = 44.7 bits (104),  Expect = 3e-04, Method: Compositional matrix adjust.
 Identities = 32/82 (39%), Positives = 43/82 (52%), Gaps = 7/82 (8%)

Query  50    PQGINLSS-TCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKDG-VCIDINE  106
             P+G   S  TC+DIDEC +  D C+    +C N  GS+ C C P Y+   +G  C DI+E
Sbjct  5420  PEGSEASHDTCVDIDEC-ENTDACQH---ECKNTFGSYQCICPPGYQLTHNGKTCQDIDE  5475

Query  107   CSTNRGNCDENSDCINLDGEEQ  128
             C     +C  N  C N+ G  Q
Sbjct  5476  CLEQNVHCGPNRMCFNMRGSYQ  5497


 Score = 42.7 bits (99),  Expect = 0.001, Method: Compositional matrix adjust.
 Identities = 52/213 (24%), Positives = 75/213 (35%), Gaps = 65/213 (30%)

Query  29    EHAESCQSGDG-FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFT  87
              + + C++  G + C C +G+  QG+     C+DI+EC Q    C  +   C N PGSF 
Sbjct  5284  RYNQICENTRGSYRCVCPRGYRSQGV--GRPCMDINECEQVPKPCAHQ---CSNTPGSFK  5338

Query  88    CGCGP--------------------------------------------YRQEKDGVCID  103
             C C P                                            YRQ    +   
Sbjct  5339  CICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSH-LYSS  5397

Query  104   INECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSN  163
              +E   +R +       I          C +G   ++D     C DI+EC EN   C   
Sbjct  5398  YSEYRNSRTSLSRTRRTIR-------KTCPEGSEASHD----TCVDIDEC-ENTDACQHE  5445

Query  164   SVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFC  196
               C N  GSY+C C  G++   +G  C   D C
Sbjct  5446  --CKNTFGSYQCICPPGYQLTHNGKTCQDIDEC  5476


 Score = 39.7 bits (91),  Expect = 0.010, Method: Compositional matrix adjust.
 Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 9/94 (9%)

Query  101   CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSIC  160
             C+DI+EC  N   C    +C N  G  Q C C  G+   ++     C+DI+EC E    C
Sbjct  5430  CVDIDECE-NTDACQH--ECKNTFGSYQ-CICPPGYQLTHN--GKTCQDIDECLEQNVHC  5483

Query  161   PSNSVCTNLAGSYKC---ECSAGFEPDSSGSGCV  191
               N +C N+ GSY+C    C   ++ D     C+
Sbjct  5484  GPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCL  5517


 Score = 33.1 bits (74),  Expect = 0.83, Method: Compositional matrix adjust.
 Identities = 37/134 (27%), Positives = 53/134 (39%), Gaps = 26/134 (19%)

Query  131   KCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGC  190
             +C  G+T ++  P   C D +EC       P +  C N  G+Y C C  G    + G  C
Sbjct  5091  QCPSGFTLDSVGP--FCADEDECAAG---NPCSHSCHNAMGTYYCSCPKGLTIAADGRTC  5145

Query  191   VTEDFCGTGKNDCDTVFAACSLVPGSFKC--ECIQGFRGAGTVNTCEPLPGNEDLACTTL  248
                D C  G++ C      C    GS++C   C  GFR                   T+ 
Sbjct  5146  QDIDECALGRHTCHA-GQDCDNTIGSYRCVVRCGSGFRR------------------TSD  5186

Query  249   GLTCGDYKYCTKST  262
             GL+C D   C +S+
Sbjct  5187  GLSCQDINECQESS  5200


 Score = 32.0 bits (71),  Expect = 1.7, Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 29/65 (44%), Gaps = 4/65 (6%)

Query  171   GSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGT  230
             G    +C +GF  DS G  C  ED C  G N C     +C    G++ C C +G   A  
Sbjct  5086  GDRSNQCPSGFTLDSVGPFCADEDECAAG-NPCS---HSCHNAMGTYYCSCPKGLTIAAD  5141

Query  231   VNTCE  235
               TC+
Sbjct  5142  GRTCQ  5146


> Hs5922009
Length=703

 Score = 80.5 bits (197),  Expect = 5e-15, Method: Compositional matrix adjust.
 Identities = 71/221 (32%), Positives = 97/221 (43%), Gaps = 20/221 (9%)

Query  36   SGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTC----GCG  91
            +GD   C+C  G+  Q ++   +C D++EC  G  +C+  G  C+N  GSF C     CG
Sbjct  193  TGDEVVCSCFVGY--QLLSDGVSCEDVNECITGSHSCR-LGESCINTVGSFRCQRDSSCG  249

Query  92   P-YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDI  150
              Y   +D  C DI+EC +   NC  +  C N  G  +     +  +G        C DI
Sbjct  250  TGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDI  309

Query  151  NECNENPSICPSNSVCTNLAGSYKCE-----CSAGFEPDSSGSGCVTEDFCGTGKNDCDT  205
            NEC    + CP    C N  GSY C+     C  G+  +  G+ CV  D C      C  
Sbjct  310  NECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGK  369

Query  206  VFAACSLVPGSFKCECIQGFRGAGT------VNTCEPLPGN  240
                C   PGSF+CEC  G+   G       VN C+  PG 
Sbjct  370  GH-RCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR  409


 Score = 78.2 bits (191),  Expect = 3e-14, Method: Compositional matrix adjust.
 Identities = 68/187 (36%), Positives = 92/187 (49%), Gaps = 18/187 (9%)

Query  57   STCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEKDGVCIDINECSTNRGNC  114
            + C+D+DECA   + C  KG  CVN PGSF C C  G Y      +C+D+NEC    G  
Sbjct  352  TRCVDVDECAPPAEPCG-KGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL  410

Query  115  DENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYK  174
              +  C N  G   LC C  G+  + D    +C DINEC+ +P     +  C N+ GSY+
Sbjct  411  CGHK-CENTLGS-YLCSCSVGFRLSVD--GRSCEDINECSSSPC----SQECANVYGSYQ  462

Query  175  CECSAGFE-PDSSGSGCVTEDFCG--TGKNDCDTVFAACSLVPGSFKCEC-IQGFRGAGT  230
            C C  G++  D  G  C   D C   TG + C      C  +PGSF+C C   G+R A  
Sbjct  463  CYCRRGYQLSDVDGVTCEDIDECALPTGGHICS---YRCINIPGSFQCSCPSSGYRLAPN  519

Query  231  VNTCEPL  237
               C+ +
Sbjct  520  GRNCQDI  526


 Score = 73.6 bits (179),  Expect = 5e-13, Method: Compositional matrix adjust.
 Identities = 64/196 (32%), Positives = 99/196 (50%), Gaps = 17/196 (8%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
            F C C+ G+   GI  S  C+D++EC +     +  G  C N  GS+ C C   +R   D
Sbjct  380  FRCECKTGYYFDGI--SRMCVDVNECQRYPG--RLCGHKCENTLGSYLCSCSVGFRLSVD  435

Query  99   GV-CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP  157
            G  C DINECS++  +     +C N+ G  Q C C +G+  + D   V C DI+EC    
Sbjct  436  GRSCEDINECSSSPCS----QECANVYGSYQ-CYCRRGYQLS-DVDGVTCEDIDECALPT  489

Query  158  SICPSNSVCTNLAGSYKCEC-SAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGS  216
                 +  C N+ GS++C C S+G+    +G  C   D C TG ++C ++   C  + G+
Sbjct  490  GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNC-SINETCFNIQGA  548

Query  217  FKC---ECIQGFRGAG  229
            F+C   EC + +R + 
Sbjct  549  FRCLAFECPENYRRSA  564


 Score = 70.1 bits (170),  Expect = 7e-12, Method: Compositional matrix adjust.
 Identities = 61/191 (31%), Positives = 87/191 (45%), Gaps = 22/191 (11%)

Query  44   CQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTC-------GCGPYRQE  96
            C+ GF    +     CIDI+EC      C   G  C+N  GS+TC       G G +  E
Sbjct  294  CKSGFIQDAL---GNCIDINECLSISAPCP-IGHTCINTEGSYTCQKNVPNCGRGYHLNE  349

Query  97   KDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNEN  156
            +   C+D++EC+     C +   C+N  G  + C+C  G+    D  +  C D+NEC   
Sbjct  350  EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR-CECKTGYYF--DGISRMCVDVNECQRY  406

Query  157  P-SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPG  215
            P  +C     C N  GSY C CS GF     G  C  ED      + C      C+ V G
Sbjct  407  PGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSC--EDINECSSSPCS---QECANVYG  459

Query  216  SFKCECIQGFR  226
            S++C C +G++
Sbjct  460  SYQCYCRRGYQ  470


 Score = 69.3 bits (168),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 60/190 (31%), Positives = 83/190 (43%), Gaps = 14/190 (7%)

Query  57   STCIDIDECAQGLDNCKQKGGDCVNIPGSFTC----GCGP-YRQEKDGVCIDINECSTNR  111
            ++C DIDEC  G+ NC      C N  GSF C     C   + Q+  G CIDINEC +  
Sbjct  258  NSCKDIDECESGIHNCL-PDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSIS  316

Query  112  GNCDENSDCINLDG----EEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCT  167
              C     CIN +G    ++ +  C +G+  N +     C D++EC      C     C 
Sbjct  317  APCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEE--GTRCVDVDECAPPAEPCGKGHRCV  374

Query  168  NLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRG  227
            N  GS++CEC  G+  D     CV  + C             C    GS+ C C  GFR 
Sbjct  375  NSPGSFRCECKTGYYFDGISRMCVDVNECQRYPG--RLCGHKCENTLGSYLCSCSVGFRL  432

Query  228  AGTVNTCEPL  237
            +    +CE +
Sbjct  433  SVDGRSCEDI  442


 Score = 47.8 bits (112),  Expect = 3e-05, Method: Compositional matrix adjust.
 Identities = 46/155 (29%), Positives = 71/155 (45%), Gaps = 11/155 (7%)

Query  72   CKQKGGDCVNIPGSFTCGCGP-YRQEKDGV-CIDINECSTNRGNCDENSDCINLDGEEQL  129
            CKQ+   C +      C C   Y+   DGV C D+NEC T   +C     CIN  G  + 
Sbjct  186  CKQQ---CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC  242

Query  130  CKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKC----ECSAGFEPDS  185
             +     TG     + +C+DI+EC      C  + +C N  GS++C    +C +GF  D+
Sbjct  243  QRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDA  302

Query  186  SGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCE  220
             G+ C+  + C +    C  +   C    GS+ C+
Sbjct  303  LGN-CIDINECLSISAPC-PIGHTCINTEGSYTCQ  335


> CE28049
Length=3767

 Score = 79.7 bits (195),  Expect = 8e-15, Method: Compositional matrix adjust.
 Identities = 81/264 (30%), Positives = 113/264 (42%), Gaps = 47/264 (17%)

Query  3     PPRLAAMGGKSSTP----------CDAGGYDHCSRVEHAESCQSGDGFWCACQKGFTPQG  52
             PP        SS P          CD    + C   + A    + DG+ C C++GF    
Sbjct  1789  PPGFKDKSPSSSRPGRLCIPVIPECDNPTLNDCDSPDRAVCTDTDDGYMCRCRQGFLDIS  1848

Query  53    INLS----STCIDI-DECAQGLDNCKQKGGDCVNIPGSFTCGCG-------------PYR  94
              ++S      C  + +ECA G+D+C + GG C + P SFTC C              P R
Sbjct  1849  PSISVKPGRLCKPLQNECALGIDDCARDGGICEDNPDSFTCRCAMNYLDVSFDRVTRPGR  1908

Query  95    QEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNN----DKPNVAC-RD  149
             + K      INEC T + +C E + C + + +  +C C +     +    ++P   C   
Sbjct  1909  KCKRL----INECQTGQNDCSEEATCTDTE-DSYICACPQSHIDLSPDTVNRPGRRCLMR  1963

Query  150   INECNENPSICPSNSVCTNLAGSYKCECSAGF---EPDSS---GSGC--VTEDFCGTGKN  201
             INEC  N   C  N+ C +   SYKC C   F    PDSS   G  C     D C TGK+
Sbjct  1964  INECTSNRHDCSPNADCIDTPESYKCRCRDDFVDESPDSSRRPGRICRPALVDECRTGKH  2023

Query  202   DCDTVFAACSLVPGSFKCECIQGF  225
             DC  V A C  +P  + C+C   F
Sbjct  2024  DCH-VNAICQDLPQGYTCQCSADF  2046


 Score = 56.6 bits (135),  Expect = 8e-08, Method: Compositional matrix adjust.
 Identities = 56/204 (27%), Positives = 88/204 (43%), Gaps = 22/204 (10%)

Query  19   AGGYDHCSRVEHAESCQSGDGFWCACQKGFTPQGIN---------LSSTCIDIDEC--AQ  67
            A G   CS   HA    + DGF C C+  +  +  +         + +   D  EC  + 
Sbjct  767  AEGRHDCS--SHATCIDTADGFTCRCKDSYRDESSDTLKHPGKNCVRTVQPDPPECDVSD  824

Query  68   GLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKDGVCIDINECSTNRGN-CDENSDCINLDG  125
             +     K   C+ +  ++ C C   Y +  DG C+ INEC+  R N C +N++CI+L  
Sbjct  825  PMSCDPAKREVCIFVENTYKCRCANGYSRLPDGRCVVINECAEPRLNTCGKNAECIDL-A  883

Query  126  EEQLCKCHKGWTGNN--DKPNVACR-DINECNENPSI---CPSNSVCTNLAGSYKCECSA  179
            E   C+C  G+   +   +P   CR  +NEC+        C  N++C +   SY C C  
Sbjct  884  EGYTCQCRSGYADISPVSQPGRICRARVNECSNKEKYNVDCSENAICADTEHSYSCRCRP  943

Query  180  GFEPDSSGSGCVTEDFCGTGKNDC  203
            GF   S+    +    C    N+C
Sbjct  944  GFADVSAAFNKLPGRRCIEAVNEC  967


 Score = 54.7 bits (130),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 58/206 (28%), Positives = 89/206 (43%), Gaps = 27/206 (13%)

Query  44    CQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC-------GPYRQE  96
             CQ G   +   ++  C+  +EC  G  +C  +   C++   S+ C C        P   E
Sbjct  1592  CQCGRNEKRHPITDICLK-NECLTGEHDC-DRSARCIDTDESYICACQSGFIDHSPNPSE  1649

Query  97    KDG-VCIDI-NECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPN----VACRD-  149
             + G VC+ + NEC      C  N+ C + + E  +C+C  G+   +  P     + C++ 
Sbjct  1650  RPGRVCVALQNECLDGSNRCSPNALCTDTE-EGYVCRCKSGFVDYSPNPQTFPGMVCKEL  1708

Query  150   INECNENPSI--CPSNSVCTNLAGSYKCECSAGF----EPDSSGSGC---VTEDFCGTGK  200
             +NEC  NP +  C  N+ C +    Y C C  GF    E  + G  C    T D C  GK
Sbjct  1709  VNECT-NPRLNQCDRNAHCIDTIEGYSCICKPGFVDMDEFGNPGRRCEQIKTNDKCSPGK  1767

Query  201   NDCDTVFAACSLVPGSFKCECIQGFR  226
             NDCD       +    + C C  GF+
Sbjct  1768  NDCDRNARCIQIGDDDYSCACPPGFK  1793


 Score = 52.8 bits (125),  Expect = 1e-06, Method: Compositional matrix adjust.
 Identities = 57/212 (26%), Positives = 89/212 (41%), Gaps = 27/212 (12%)

Query  38    DGFWCACQKGF---TPQGINLSSTCID-IDECAQGLDNCKQKGGDCVNIPGSFTCGC---  90
             +G+ C C+ GF   +P        C + ++ECA    N   K   C +   S+ C C   
Sbjct  2233  EGYECECRDGFIDVSPSPTLKGRACRELVNECANSRLNDCDKNARCKDTMDSYECDCPVN  2292

Query  91    ----GPYRQEKDGVCID-INECSTNRGNCDENSDCINLDGEEQL-CKCHKGWT----GNN  140
                  P       VC+  INEC +   +CD ++ C   D E+   C+C  G+       +
Sbjct  2293  SKDISPSPSFPGRVCLMFINECESGVHDCDPSATC--RDNEQSFTCECPSGFVDRSPNKH  2350

Query  141   DKPNVAC-RDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDS------SGSGCVTE  193
              +P   C + ++EC E    C S++ C +L   Y CEC  G+   S       G  C   
Sbjct  2351  ARPGRVCVKLVDECREGRHTCSSHADCRDLEEGYTCECRDGYVDRSPNLASQPGRVCSAP  2410

Query  194   DFCGTGKNDCDTVFAACSLVPGSFKCECIQGF  225
             + C    +DC +      L    ++C CIQG+
Sbjct  2411  EVCPPN-HDCSSAAVCEPLGGMKYQCVCIQGY  2441


 Score = 52.0 bits (123),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 11/116 (9%)

Query  74    QKGGDCVNIPGSFTCGCGPYRQEKDGVCIDI---NECSTNRGNCDENSDCINLDGEEQLC  130
             +K   C+     +TC CG  R EK     DI   NEC T   +CD ++ CI+ D E  +C
Sbjct  1578  RKRQQCLPRGNIYTCQCG--RNEKRHPITDICLKNECLTGEHDCDRSARCIDTD-ESYIC  1634

Query  131   KCHKGWTGNN----DKPNVACRDI-NECNENPSICPSNSVCTNLAGSYKCECSAGF  181
              C  G+  ++    ++P   C  + NEC +  + C  N++CT+    Y C C +GF
Sbjct  1635  ACQSGFIDHSPNPSERPGRVCVALQNECLDGSNRCSPNALCTDTEEGYVCRCKSGF  1690


 Score = 50.1 bits (118),  Expect = 6e-06, Method: Compositional matrix adjust.
 Identities = 62/236 (26%), Positives = 94/236 (39%), Gaps = 32/236 (13%)

Query  21    GYDHCSRVEHAESCQSGDGFWCACQKG---FTPQGINLSST--CIDIDECAQGLDNCKQK  75
             G + CS  E A    + D + CAC +     +P  +N       + I+EC     +C   
Sbjct  1920  GQNDCS--EEATCTDTEDSYICACPQSHIDLSPDTVNRPGRRCLMRINECTSNRHDC-SP  1976

Query  76    GGDCVNIPGSFTCGC-------GPYRQEKDG-VCID--INECSTNRGNCDENSDCINLDG  125
               DC++ P S+ C C        P    + G +C    ++EC T + +C  N+ C +L  
Sbjct  1977  NADCIDTPESYKCRCRDDFVDESPDSSRRPGRICRPALVDECRTGKHDCHVNAICQDL-P  2035

Query  126   EEQLCKCHKGWT----GNNDKPNVACRDIN-----ECNE---NPSICPSNSVCTNLAGSY  173
             +   C+C   +          P   C+        EC     N      N VC  + G  
Sbjct  2036  QGYTCQCSADFVDVSPHRASHPGRLCQPRPTPPPPECRLDGGNQCKVHLNEVCRLMGGEP  2095

Query  174   KCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAG  229
             KC C   ++ DSSGS  +  +   T  NDC T       V G + C+C  GF+  G
Sbjct  2096  KCSCPVNYQRDSSGSCSIINECLFTQLNDCHTAADCIDQVQG-YTCQCRDGFKDIG  2150


 Score = 49.7 bits (117),  Expect = 9e-06, Method: Compositional matrix adjust.
 Identities = 57/216 (26%), Positives = 85/216 (39%), Gaps = 32/216 (14%)

Query  40    FWCACQKGFTPQGINLSS----TCID-IDECAQGLDNCKQKGGDCVNIPGSFTCGC----  90
             F C C  GF  +  N  +     C+  +DEC +G   C     DC ++   +TC C    
Sbjct  2334  FTCECPSGFVDRSPNKHARPGRVCVKLVDECREGRHTCSSHA-DCRDLEEGYTCECRDGY  2392

Query  91    ---GPYRQEKDG-VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNN--DKPN  144
                 P    + G VC     C  N  +C   + C  L G +  C C +G+   +   +  
Sbjct  2393  VDRSPNLASQPGRVCSAPEVCPPNH-DCSSAAVCEPLGGMKYQCVCIQGYVDQSPGSQKG  2451

Query  145   VACRDINECNE-NPSICPSNSVCTNLAGSYKCECSAGF---EPDSSGSGCVTEDFCGTG-  199
               C   N C++   + C  N++C +    Y+CEC  GF    PDSS  G V E       
Sbjct  2452  RVCVRNNACHDPRLNTCSRNAICYDEPRGYRCECKRGFMDRSPDSSQRGRVCEPPPPPSP  2511

Query  200   ----------KNDCDTVFAACSLVPGSFKCECIQGF  225
                       +NDC       +    S+ CEC+ G+
Sbjct  2512  PPRHPCQDPERNDCHPAGTCRATGAQSYTCECLSGY  2547


 Score = 49.3 bits (116),  Expect = 1e-05, Method: Compositional matrix adjust.
 Identities = 59/222 (26%), Positives = 94/222 (42%), Gaps = 28/222 (12%)

Query  93    YRQEKDGVCIDINEC-STNRGNCDENSDCINLDGEEQLCKCHKGW--TGNNDKPNVACRD  149
             Y+++  G C  INEC  T   +C   +DCI+   +   C+C  G+   G+  +P   C+ 
Sbjct  2103  YQRDSSGSCSIINECLFTQLNDCHTAADCID-QVQGYTCQCRDGFKDIGDRRRPGRMCKP  2161

Query  150   -INECNENPSI--CPSNSVCTNLAGSYKCECSAGFEPDSSGS-----GCVTEDFCGTGKN  201
              +NEC + P +  C  N+ C +L   Y+C+C+ GF   S G        +T +      N
Sbjct  2162  MVNEC-QYPHLNDCHQNAACIDLEEGYECKCNQGFMDHSHGRPGRICKQLTNECLRPSLN  2220

Query  202   DCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCEPLPGNEDLACTTLGLTCGDYKY--CT  259
              CD   A C      ++CEC  GF          P P  +  AC  L   C + +   C 
Sbjct  2221  SCDRN-ARCIDKEEGYECECRDGFIDVS------PSPTLKGRACRELVNECANSRLNDCD  2273

Query  260   KSTTQAGLWECTDKAASEQLAVFIANGATSDTPSWVWAVVVL  301
             K+        C D   S +    + +   S +PS+   V ++
Sbjct  2274  KNA------RCKDTMDSYECDCPVNSKDISPSPSFPGRVCLM  2309


 Score = 45.1 bits (105),  Expect = 2e-04, Method: Compositional matrix adjust.
 Identities = 65/224 (29%), Positives = 94/224 (41%), Gaps = 35/224 (15%)

Query  32   ESCQ--SGDGFWCACQKGFTPQGINLSSTCID-IDECAQGLDNCKQKGGDCVNIPGSFTC  88
            ESCQ  S   + C C++GFT        TC + IDECAQG  +C  +   CV+    + C
Sbjct  390  ESCQKNSESKYECICREGFTI----FEGTCRELIDECAQGKHDCHPEAR-CVDALIGYEC  444

Query  89   GCGPYRQEKDGVCID------------INECSTNRGN-CDENSDCINLDGEEQLCKCHKG  135
             C   R+      ID            INEC+    N C +N+ C++       C+C   
Sbjct  445  LC---REGYLDTSIDPKARPGRKCRKLINECTNALMNDCSQNARCLD-KPIGYTCRCQDD  500

Query  136  WTGNND----KPNVAC-RDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGC  190
            +   +     KP   C + INEC  N   C ++++C +    Y C C  GF  DSS +  
Sbjct  501  YVDVSREGARKPGRNCTQAINECASNLHNCDTHAICQDQPVGYSCRCPFGF-IDSSPTAL  559

Query  191  VTEDFCGTGKNDCDTVFAACSL----VPGSFKCECIQGFRGAGT  230
                 C    N+  T     S       G   C+C+ G++  GT
Sbjct  560  EPGRKCVQANNEAATTSTTTSQCIKEKNGETVCKCLLGYKNVGT  603


 Score = 44.7 bits (104),  Expect = 3e-04, Method: Compositional matrix adjust.
 Identities = 50/172 (29%), Positives = 70/172 (40%), Gaps = 19/172 (11%)

Query  38    DGFWCAC---QKGFTPQGINLSSTC-IDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPY  93
             +G+ C C    K  +P        C + ++ECA    N      DC +    + C C   
Sbjct  2641  NGYTCQCPINAKDQSPDPRKPGRICSLSVNECANPSLNSCSAFADCFDEENGYRCRCRNG  2700

Query  94    RQEKDGV------CIDINEC-STNRGNCDENSDCINLDG-EEQLCKCHKGWTGNNDKPNV  145
               + D           INEC S+N  +CD N++CI+  G  +  CK      G    P  
Sbjct  2701  YHDDDPAHPGHRCSFMINECDSSNLNDCDRNANCIDTAGGYDCACKAPYRDEGPPQSPGR  2760

Query  146   ACRDINEC-NENPSICPSNSVCTNLAGSYKCECSAGF-----EPDSSGSGCV  191
              CR +NEC N N + C  N+ C +L   Y C C  GF      P   G  C+
Sbjct  2761  ICR-LNECLNPNRNTCDRNADCRDLDYGYTCTCRHGFYDQSPNPQEPGRICI  2811


 Score = 43.5 bits (101),  Expect = 7e-04, Method: Compositional matrix adjust.
 Identities = 60/248 (24%), Positives = 92/248 (37%), Gaps = 43/248 (17%)

Query  12   KSSTPCDAGGYDHCSRVEHAESCQSGDGFWCACQKGFTPQGINLS---STCID-IDECAQ  67
            K + PC       C  V    S Q G  F C C KGFT    +       C+  +DECA 
Sbjct  613  KRANPCQDYSLHDCDPVAECFSEQPG-YFQCQCPKGFTDSSADKRFPGRKCVRAVDECAL  671

Query  68   GLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEE  127
            G   C     DC++    +TC C     +       ++   +   +C +   C N+D   
Sbjct  672  GRHTCDPHA-DCIDTHQGYTCKCRSGWSD-----TSLDPLRSPGRSCKKADMCSNIDCAA  725

Query  128  Q----------LCKCHKGW---TGNNDKP-NVACRDI-NECNENPSICPSNSVCTNLAGS  172
            +          +C+C  G+   +  + +P    CR + NEC E    C S++ C + A  
Sbjct  726  EAECRETPIGPMCQCVSGYVDVSRQHGRPAGRVCRAVVNECAEGRHDCSSHATCIDTADG  785

Query  173  YKCECSAGFEPDSS------GSGCVTEDFCGTGKNDCDTV---------FAACSLVPGSF  217
            + C C   +  +SS      G  CV          +CD              C  V  ++
Sbjct  786  FTCRCKDSYRDESSDTLKHPGKNCVRT--VQPDPPECDVSDPMSCDPAKREVCIFVENTY  843

Query  218  KCECIQGF  225
            KC C  G+
Sbjct  844  KCRCANGY  851


 Score = 40.8 bits (94),  Expect = 0.004, Method: Compositional matrix adjust.
 Identities = 45/161 (27%), Positives = 65/161 (40%), Gaps = 17/161 (10%)

Query  79    CVNIPGSFTCGC--GPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGW  136
             CV   G   C C    +R   DG C   + CS  R  CD+N+ C+N   +   C+C  G+
Sbjct  1046  CVQRHGQHNCECVETAFRY-TDGSCRVYSACS-KRNTCDKNAICLNR-FDSYTCQCRPGY  1102

Query  137   TGNN----DKPNVACRD-INECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCV  191
                +    + P   C++ INEC  + + C   + C +    Y C+C  GF   SS     
Sbjct  1103  IDLSADLTNAPGRICKELINECASSDNECSPYARCIDATNGYACQCLDGFIDVSSRYNKP  1162

Query  192   TEDFCGTGKNDCDTVF-------AACSLVPGSFKCECIQGF  225
                 C    N+C           A C   P  + C+C  GF
Sbjct  1163  PGRQCTNSNNECSEKSLNTCDENADCVDTPDGYTCQCYGGF  1203


 Score = 37.4 bits (85),  Expect = 0.048, Method: Compositional matrix adjust.
 Identities = 61/240 (25%), Positives = 85/240 (35%), Gaps = 53/240 (22%)

Query  12    KSSTPCDAGGYDHCSRVEHAESCQSGDGFWCACQKGFTPQGI-----------NLSSTCI  60
             ++ T CD    +HC+ VE+           C C +GFT                L ++CI
Sbjct  1428  RTQTGCDRSLNEHCA-VENGRP-------RCVCPEGFTRHPFTRVCGGDLCNPQLITSCI  1479

Query  61    DIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEKDGVCIDINE----------CS  108
               +EC              +    +F C C  G  R  + G C+ + E          C 
Sbjct  1480  FPEECQ-------------ITPYKNFRCSCPEGYNRDYRSGFCVSVKEVQISPQHDANCH  1526

Query  109   TNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNEN-PSIC--PSNSV  165
                  C EN  C N DG +  C+C  G+       N  C     CN N P  C       
Sbjct  1527  NGGVRCSENERCTN-DGSDWFCECLPGFERIR---NGQCAYPGSCNPNDPMSCDVRKRQQ  1582

Query  166   CTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGF  225
             C      Y C+C    +       C+  + C TG++DCD   A C     S+ C C  GF
Sbjct  1583  CLPRGNIYTCQCGRNEKRHPITDICLKNE-CLTGEHDCDRS-ARCIDTDESYICACQSGF  1640


 Score = 36.6 bits (83),  Expect = 0.076, Method: Compositional matrix adjust.
 Identities = 55/213 (25%), Positives = 82/213 (38%), Gaps = 29/213 (13%)

Query  33   SCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--  90
            +C+  D +    ++G    G N +     I+ECA  L NC      C + P  ++C C  
Sbjct  494  TCRCQDDYVDVSREGARKPGRNCTQA---INECASNLHNCDTHAI-CQDQPVGYSCRCPF  549

Query  91   -----GPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNV  145
                  P   E    C+  N  +         S CI     E +CKC  G+     K ++
Sbjct  550  GFIDSSPTALEPGRKCVQAN--NEAATTSTTTSQCIKEKNGETVCKCLLGYKNVGTKTHL  607

Query  146  ACRDINECNENPSICPSNSVCTNLA-------GSYKCECSAGFEPDSS-----GSGCVTE  193
             C+   E   NP    S   C  +A       G ++C+C  GF   S+     G  CV  
Sbjct  608  NCQ--MEKRANPCQDYSLHDCDPVAECFSEQPGYFQCQCPKGFTDSSADKRFPGRKCVRA  665

Query  194  -DFCGTGKNDCDTVFAACSLVPGSFKCECIQGF  225
             D C  G++ CD   A C      + C+C  G+
Sbjct  666  VDECALGRHTCDP-HADCIDTHQGYTCKCRSGW  697


 Score = 35.8 bits (81),  Expect = 0.13, Method: Compositional matrix adjust.
 Identities = 36/123 (29%), Positives = 55/123 (44%), Gaps = 26/123 (21%)

Query  77    GDCVNIPG-SFTCGCGP-YR----QEKDGVCIDI---NECSTNRGN-CDENSDCINLDGE  126
             G C+ I   ++ C CG  YR    Q     C+ +   NEC     N C EN+ CI+L+  
Sbjct  3189  GKCIEISKYAYKCECGVGYRDINPQSPGKKCLPVHGFNECERKEDNECSENARCIDLEHL  3248

Query  127   EQLCKCHKGWTGNNDKPNVA--------CRDINECNENPSICPSNSVCTNLAGSYKCECS  178
              + C+C   +   +   +V         C D+N        CP+N+ C N+    +C+C 
Sbjct  3249  YK-CECLPSYYDTSPVGSVPGSLCVLDYCSDVN-------FCPTNTTCKNMEQQAECKCD  3300

Query  179   AGF  181
             AGF
Sbjct  3301  AGF  3303


 Score = 35.4 bits (80),  Expect = 0.18, Method: Compositional matrix adjust.
 Identities = 38/144 (26%), Positives = 62/144 (43%), Gaps = 26/144 (18%)

Query  100   VCIDINECSTNRGNCDENSDCINLDGEEQL-CKCHKGWTGNN----DKPNVACRD-INEC  153
             VC+D  +      +C   + C  ++G E+  CKC  G+T  +     +P   C+  INEC
Sbjct  2568  VCLDPEQ-----NDCHAAAICSEVNGPEKYTCKCRDGYTDESPDPLRRPGRICKGLINEC  2622

Query  154   -NENPSICPSNSVCTNLAGSYKCECSAGFE---PDSSGSGCVTEDFCGTGKNDCD-----  204
              + + + C S +VC +L   Y C+C    +   PD    G +    C    N+C      
Sbjct  2623  LDRSLNDCHSLAVCKDLPNGYTCQCPINAKDQSPDPRKPGRI----CSLSVNECANPSLN  2678

Query  205   --TVFAACSLVPGSFKCECIQGFR  226
               + FA C      ++C C  G+ 
Sbjct  2679  SCSAFADCFDEENGYRCRCRNGYH  2702


 Score = 34.3 bits (77),  Expect = 0.36, Method: Compositional matrix adjust.
 Identities = 44/185 (23%), Positives = 73/185 (39%), Gaps = 43/185 (23%)

Query  39    GFWCACQKGFTPQGINLSS---TCIDI---DECAQGLDNCKQKGGDCVNIPGSFTCGCGP  92
              + C C  G+  + IN  S    C+ +   +EC +  DN   +   C+++   + C C P
Sbjct  3198  AYKCECGVGY--RDINPQSPGKKCLPVHGFNECERKEDNECSENARCIDLEHLYKCECLP  3255

Query  93    YRQEKDGV------------CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTG--  138
                +   V            C D+N C T       N+ C N++ + + CKC  G+    
Sbjct  3256  SYYDTSPVGSVPGSLCVLDYCSDVNFCPT-------NTTCKNMEQQAE-CKCDAGFMDIR  3307

Query  139   ----------NNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGF---EPDS  185
                        +D   +  RD++EC    + C   + C + A  Y C+C  G+    PD 
Sbjct  3308  KSEKRTALMLGDDTLCMHVRDVDECALGLNNCSGVAHCIDRAVGYTCKCPDGYIDGNPDE  3367

Query  186   SGSGC  190
              G  C
Sbjct  3368  PGRVC  3372


 Score = 33.5 bits (75),  Expect = 0.60, Method: Compositional matrix adjust.
 Identities = 47/176 (26%), Positives = 69/176 (39%), Gaps = 18/176 (10%)

Query  111   RGNCDENSDCINLDGEEQLCKCHKGWTG-NNDKPNVACRDI---NEC-NENPSICPSNSV  165
             + +CD +  CI +      C+C  G+   N   P   C  +   NEC  +  + C  N+ 
Sbjct  3182  KNDCDPHGKCIEISKYAYKCECGVGYRDINPQSPGKKCLPVHGFNECERKEDNECSENAR  3241

Query  166   CTNLAGSYKCECSAGFEPDS-----SGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCE  220
             C +L   YKCEC   +   S      GS CV  D+C +  N C T    C  +    +C+
Sbjct  3242  CIDLEHLYKCECLPSYYDTSPVGSVPGSLCVL-DYC-SDVNFCPTN-TTCKNMEQQAECK  3298

Query  221   CIQGFRGAGTVNTCEPLPGNEDLACTTLGLTCGDYKYCTKSTTQ-AGLWECTDKAA  275
             C  GF           L   +D    TL +   D   C       +G+  C D+A 
Sbjct  3299  CDAGFMDIRKSEKRTALMLGDD----TLCMHVRDVDECALGLNNCSGVAHCIDRAV  3350


 Score = 33.5 bits (75),  Expect = 0.62, Method: Compositional matrix adjust.
 Identities = 41/149 (27%), Positives = 60/149 (40%), Gaps = 22/149 (14%)

Query  75    KGGDCVNIPGSFTCGCGP--------YRQEKDGVCID-INECSTNRGNCDENSDCINLDG  125
             K   C+N   S+TC C P               +C + INEC+++   C   + CI+   
Sbjct  1083  KNAICLNRFDSYTCQCRPGYIDLSADLTNAPGRICKELINECASSDNECSPYARCIDATN  1142

Query  126   EEQLCKCHKGW----TGNNDKPNVACRDIN-ECNENP-SICPSNSVCTNLAGSYKCECSA  179
                 C+C  G+    +  N  P   C + N EC+E   + C  N+ C +    Y C+C  
Sbjct  1143  G-YACQCLDGFIDVSSRYNKPPGRQCTNSNNECSEKSLNTCDENADCVDTPDGYTCQCYG  1201

Query  180   GFEPDSS------GSGCVTEDFCGTGKND  202
             GF   SS      G  C  +  C   K D
Sbjct  1202  GFVDVSSNANLPPGRVCTVQTTCPKQKTD  1230


> Hs4557733
Length=1821

 Score = 79.3 bits (194),  Expect = 9e-15, Method: Compositional matrix adjust.
 Identities = 87/271 (32%), Positives = 115/271 (42%), Gaps = 44/271 (16%)

Query  21    GYDHCSRVEHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCV  80
             G +HC+   H E   S   F+C C  GF        ++C D+DECA   D C   GG CV
Sbjct  1182  GEEHCA--PHGECLNSHGSFFCLCAPGFV--SAEGGTSCQDVDECAT-TDPCV--GGHCV  1234

Query  81    NIPGSFTCGC--GPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQ-LCKCHKGWT  137
             N  GSF C C  G     + G C+DI+EC            C N  G  + +  C  G+ 
Sbjct  1235  NTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGF-  1293

Query  138   GNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCG  197
               +  PN  C DI+EC  N ++C S+  C N  GS++C C  GFE   SG  CV      
Sbjct  1294  --HMAPNGDCIDIDEC-ANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVD-----  1345

Query  198   TGKNDCDTVFAACSL-----VPGSFKCECIQGF------------RGAGTVNTCEPLPGN  240
                N+C+ + A C       V GSF C C                RGAG  +  E   G+
Sbjct  1346  --VNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGD  1403

Query  241   EDLACTTLGLTCGDYKYCT------KSTTQA  265
                A T +    G   +        ++TTQA
Sbjct  1404  HAPAPTRMDCYSGQKGHAPCSSVLGRNTTQA  1434


 Score = 79.3 bits (194),  Expect = 1e-14, Method: Compositional matrix adjust.
 Identities = 69/193 (35%), Positives = 98/193 (50%), Gaps = 19/193 (9%)

Query  43    ACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEKDGV  100
             AC++G+  Q    S +C+D++EC   L       G C N+ GSF C C  G      +  
Sbjct  996   ACEEGYRGQ----SGSCVDVNEC---LTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKG  1048

Query  101   CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSIC  160
             C D++EC++ R +C     C+N +G      C  G+  N D    AC D++EC   P +C
Sbjct  1049  CQDVDECAS-RASCP-TGLCLNTEGSFACSACENGYWVNED--GTACEDLDEC-AFPGVC  1103

Query  161   PSNSVCTNLAGSYKC-ECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKC  219
             PS  VCTN AGS+ C +C  G+ P   G  C   D C   ++ C  +   C    GS++C
Sbjct  1104  PSG-VCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSC--LGGECKNTVGSYQC  1160

Query  220   ECIQGFRGA-GTV  231
              C QGF+ A GTV
Sbjct  1161  LCPQGFQLANGTV  1173


 Score = 75.5 bits (184),  Expect = 1e-13, Method: Compositional matrix adjust.
 Identities = 66/189 (34%), Positives = 91/189 (48%), Gaps = 18/189 (9%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQ-GLDNCKQKGGDCVNIPGSFTCGCGP-YRQEK  97
             + C C  G+T      +  C DI+EC Q G+ +    GG C N  GS+ C C   Y   +
Sbjct  909   YSCFCYPGYTLATSGATQECQDINECEQPGVCS----GGQCTNTEGSYHCECDQGYIMVR  964

Query  98    DGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP  157
              G C DINEC  + G C +   C+N  G      C +G+ G +     +C D+NEC   P
Sbjct  965   KGHCQDINECR-HPGTCPDGR-CVNSPGSYTCLACEEGYRGQSG----SCVDVNEC-LTP  1017

Query  158   SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSF  217
              +C ++  CTNL GS++C C  G+E  S   GC   D C + +  C T    C    GSF
Sbjct  1018  GVC-AHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECAS-RASCPTGL--CLNTEGSF  1073

Query  218   KCE-CIQGF  225
              C  C  G+
Sbjct  1074  ACSACENGY  1082


 Score = 69.7 bits (169),  Expect = 9e-12, Method: Compositional matrix adjust.
 Identities = 69/197 (35%), Positives = 91/197 (46%), Gaps = 31/197 (15%)

Query  38    DGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQE  96
             DG+ C C  G+  Q     + C D +EC +  D CK KG  C+N  GS++C C P Y   
Sbjct  866   DGYRCVCSPGY--QLHPSQAYCTDDNECLR--DPCKGKG-RCINRVGSYSCFCYPGYTLA  920

Query  97    KDGV---CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINEC  153
               G    C DINEC    G C     C N +G    C+C +G+          C+DINEC
Sbjct  921   TSGATQECQDINECE-QPGVCS-GGQCTNTEGSYH-CECDQGYIMVRKG---HCQDINEC  974

Query  154   NENPSICPSNSVCTNLAGSYKC-ECSAGFEPDSSG----SGCVTEDFCGTGKNDCDTVFA  208
               +P  CP +  C N  GSY C  C  G+   S      + C+T   C  GK        
Sbjct  975   R-HPGTCP-DGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGK--------  1024

Query  209   ACSLVPGSFKCECIQGF  225
              C+ + GSF+C C QG+
Sbjct  1025  -CTNLEGSFRCSCEQGY  1040


 Score = 68.6 bits (166),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 63/174 (36%), Positives = 75/174 (43%), Gaps = 23/174 (13%)

Query  62    IDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQ--EKDGVCIDINECSTNRGNCDENSD  119
             ID CA G  N    G  CVN+P  + C C P  Q       C D NEC   R  C     
Sbjct  845   IDRCAAGATNVCGPG-TCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECL--RDPCKGKGR  901

Query  120   CINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSA  179
             CIN  G    C C+ G+T         C+DINEC E P +C S   CTN  GSY CEC  
Sbjct  902   CINRVGSYS-CFCYPGYTLATSGATQECQDINEC-EQPGVC-SGGQCTNTEGSYHCECDQ  958

Query  180   GFEPDSSG-----SGCVTEDFCGTGKNDCDTVFAACSLVPGSFKC-ECIQGFRG  227
             G+     G     + C     C  G+         C   PGS+ C  C +G+RG
Sbjct  959   GYIMVRKGHCQDINECRHPGTCPDGR---------CVNSPGSYTCLACEEGYRG  1003


 Score = 66.6 bits (161),  Expect = 6e-11, Method: Compositional matrix adjust.
 Identities = 63/190 (33%), Positives = 86/190 (45%), Gaps = 18/190 (9%)

Query  44    CQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDG-VCI  102
             C  G+ P    L  +C D+DEC     +C   GG+C N  GS+ C C    Q  +G VC 
Sbjct  1120  CDGGYRPS--PLGDSCEDVDECEDPQSSCL--GGECKNTVGSYQCLCPQGFQLANGTVCE  1175

Query  103   DINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINEC-NENPSICP  161
             D+NEC     +C  + +C+N  G    C C  G+         +C+D++EC   +P +  
Sbjct  1176  DVNEC-MGEEHCAPHGECLNSHG-SFFCLCAPGFVSAEG--GTSCQDVDECATTDPCV--  1229

Query  162   SNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFC-GTGKNDCDTVFAACSLVPGSFKCE  220
                 C N  GS+ C C  GF+P      CV  D C   G   C T    C   PGS++C 
Sbjct  1230  -GGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTW--KCENSPGSYRCV  1286

Query  221   --CIQGFRGA  228
               C  GF  A
Sbjct  1287  LGCQPGFHMA  1296


 Score = 42.4 bits (98),  Expect = 0.001, Method: Compositional matrix adjust.
 Identities = 25/81 (30%), Positives = 43/81 (53%), Gaps = 5/81 (6%)

Query  116   ENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNE--NPSICPSNSVCTNLAGSY  173
             EN  C+ +  E   C C +G+    D  ++AC D+NEC++   P++   +  C N  GSY
Sbjct  1744  ENGRCVRVR-EGYTCDCFEGF--QLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSY  1800

Query  174   KCECSAGFEPDSSGSGCVTED  194
             +C CS G+  ++    C  ++
Sbjct  1801  RCHCSPGYVAEAGPPHCTAKE  1821


 Score = 31.6 bits (70),  Expect = 2.6, Method: Compositional matrix adjust.
 Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 2/47 (4%)

Query  147  CRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTE  193
            C+DINEC     +C  ++ C N  GSY C C  G   D S S CV++
Sbjct  620  CQDINEC-LTLGLC-KDAECVNTRGSYLCTCRPGLMLDPSRSRCVSD  664


 Score = 31.2 bits (69),  Expect = 3.0, Method: Compositional matrix adjust.
 Identities = 23/65 (35%), Positives = 26/65 (40%), Gaps = 5/65 (7%)

Query  157   PSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGS  216
             P +CP N  C N    Y C C+ GF  D+S   C   D C     D       C    GS
Sbjct  1494  PGLCP-NGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDEC----QDLACENGECVNTEGS  1548

Query  217   FKCEC  221
             F C C
Sbjct  1549  FHCFC  1553


 Score = 31.2 bits (69),  Expect = 3.7, Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 29/71 (40%), Gaps = 15/71 (21%)

Query  163   NSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDT--------VFAACSLVP  214
             N  C  +   Y C+C  GF+ D++   CV         N+CD         V   C    
Sbjct  1745  NGRCVRVREGYTCDCFEGFQLDAAHMACVD-------VNECDDLNGPAVLCVHGYCENTE  1797

Query  215   GSFKCECIQGF  225
             GS++C C  G+
Sbjct  1798  GSYRCHCSPGY  1808


 Score = 29.6 bits (65),  Expect = 8.4, Method: Compositional matrix adjust.
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 6/54 (11%)

Query  39    GFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP  92
             G+ C C  GF     +    C D DEC     +   + G+CVN  GSF C C P
Sbjct  1508  GYVCLCNPGFHYDASH--KKCEDHDEC----QDLACENGECVNTEGSFHCFCSP  1555


> Hs5922007
Length=601

 Score = 79.0 bits (193),  Expect = 1e-14, Method: Compositional matrix adjust.
 Identities = 71/221 (32%), Positives = 97/221 (43%), Gaps = 20/221 (9%)

Query  36   SGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTC----GCG  91
            +GD   C+C  G+  Q ++   +C D++EC  G  +C+  G  C+N  GSF C     CG
Sbjct  193  TGDEVVCSCFVGY--QLLSDGVSCEDVNECITGSHSCR-LGESCINTVGSFRCQRDSSCG  249

Query  92   P-YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDI  150
              Y   +D  C DI+EC +   NC  +  C N  G  +     +  +G        C DI
Sbjct  250  TGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDI  309

Query  151  NECNENPSICPSNSVCTNLAGSYKCE-----CSAGFEPDSSGSGCVTEDFCGTGKNDCDT  205
            NEC    + CP    C N  GSY C+     C  G+  +  G+ CV  D C      C  
Sbjct  310  NECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGK  369

Query  206  VFAACSLVPGSFKCECIQGFRGAGT------VNTCEPLPGN  240
                C   PGSF+CEC  G+   G       VN C+  PG 
Sbjct  370  GH-RCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR  409


 Score = 76.6 bits (187),  Expect = 7e-14, Method: Compositional matrix adjust.
 Identities = 68/187 (36%), Positives = 92/187 (49%), Gaps = 18/187 (9%)

Query  57   STCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEKDGVCIDINECSTNRGNC  114
            + C+D+DECA   + C  KG  CVN PGSF C C  G Y      +C+D+NEC    G  
Sbjct  352  TRCVDVDECAPPAEPCG-KGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL  410

Query  115  DENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYK  174
              +  C N  G   LC C  G+  + D    +C DINEC+ +P     +  C N+ GSY+
Sbjct  411  CGHK-CENTLGS-YLCSCSVGFRLSVD--GRSCEDINECSSSPC----SQECANVYGSYQ  462

Query  175  CECSAGFE-PDSSGSGCVTEDFCG--TGKNDCDTVFAACSLVPGSFKCEC-IQGFRGAGT  230
            C C  G++  D  G  C   D C   TG + C      C  +PGSF+C C   G+R A  
Sbjct  463  CYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY---RCINIPGSFQCSCPSSGYRLAPN  519

Query  231  VNTCEPL  237
               C+ +
Sbjct  520  GRNCQDI  526


 Score = 68.2 bits (165),  Expect = 3e-11, Method: Compositional matrix adjust.
 Identities = 62/193 (32%), Positives = 89/193 (46%), Gaps = 26/193 (13%)

Query  44   CQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTC-------GCGPYRQE  96
            C+ GF    +     CIDI+EC      C   G  C+N  GS+TC       G G +  E
Sbjct  294  CKSGFIQDALG---NCIDINECLSISAPCP-IGHTCINTEGSYTCQKNVPNCGRGYHLNE  349

Query  97   KDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNEN  156
            +   C+D++EC+     C +   C+N  G  + C+C  G+    D  +  C D+NEC   
Sbjct  350  EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR-CECKTGYYF--DGISRMCVDVNECQRY  406

Query  157  P-SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDT--VFAACSLV  213
            P  +C     C N  GSY C CS GF     G  C  ED      N+C +      C+ V
Sbjct  407  PGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSC--EDI-----NECSSSPCSQECANV  457

Query  214  PGSFKCECIQGFR  226
             GS++C C +G++
Sbjct  458  YGSYQCYCRRGYQ  470


 Score = 68.2 bits (165),  Expect = 3e-11, Method: Compositional matrix adjust.
 Identities = 61/192 (31%), Positives = 82/192 (42%), Gaps = 18/192 (9%)

Query  57   STCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDGV-------CIDINECST  109
            ++C DIDEC  G+ NC      C N  GSF C   P  Q K G        CIDINEC +
Sbjct  258  NSCKDIDECESGIHNCL-PDFICQNTLGSFRCR--PKLQCKSGFIQDALGNCIDINECLS  314

Query  110  NRGNCDENSDCINLDG----EEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSV  165
                C     CIN +G    ++ +  C +G+  N +     C D++EC      C     
Sbjct  315  ISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEE--GTRCVDVDECAPPAEPCGKGHR  372

Query  166  CTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGF  225
            C N  GS++CEC  G+  D     CV  + C             C    GS+ C C  GF
Sbjct  373  CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPG--RLCGHKCENTLGSYLCSCSVGF  430

Query  226  RGAGTVNTCEPL  237
            R +    +CE +
Sbjct  431  RLSVDGRSCEDI  442


 Score = 49.3 bits (116),  Expect = 1e-05, Method: Compositional matrix adjust.
 Identities = 49/140 (35%), Positives = 68/140 (48%), Gaps = 14/140 (10%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEK  97
            + C+C  GF       S  C DI+EC+     C Q   +C N+ GS+ C C  G    + 
Sbjct  422  YLCSCSVGFRLSVDGRS--CEDINECSSS--PCSQ---ECANVYGSYQCYCRRGYQLSDV  474

Query  98   DGV-CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPN-VACRDINECNE  155
            DGV C DI+EC+   G    +  CIN+ G  Q C C    +G    PN   C+DI+EC  
Sbjct  475  DGVTCEDIDECALPTGGHICSYRCINIPGSFQ-CSCPS--SGYRLAPNGRNCQDIDECVT  531

Query  156  NPSICPSNSVCTNLAGSYKC  175
                C  N  C N+ G+++C
Sbjct  532  GIHNCSINETCFNIQGAFRC  551


> Hs5922011
Length=566

 Score = 78.6 bits (192),  Expect = 2e-14, Method: Compositional matrix adjust.
 Identities = 71/221 (32%), Positives = 97/221 (43%), Gaps = 20/221 (9%)

Query  36   SGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTC----GCG  91
            +GD   C+C  G+  Q ++   +C D++EC  G  +C+  G  C+N  GSF C     CG
Sbjct  193  TGDEVVCSCFVGY--QLLSDGVSCEDVNECITGSHSCR-LGESCINTVGSFRCQRDSSCG  249

Query  92   P-YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDI  150
              Y   +D  C DI+EC +   NC  +  C N  G  +     +  +G        C DI
Sbjct  250  TGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDI  309

Query  151  NECNENPSICPSNSVCTNLAGSYKCE-----CSAGFEPDSSGSGCVTEDFCGTGKNDCDT  205
            NEC    + CP    C N  GSY C+     C  G+  +  G+ CV  D C      C  
Sbjct  310  NECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGK  369

Query  206  VFAACSLVPGSFKCECIQGFRGAGT------VNTCEPLPGN  240
                C   PGSF+CEC  G+   G       VN C+  PG 
Sbjct  370  GH-RCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR  409


 Score = 76.3 bits (186),  Expect = 9e-14, Method: Compositional matrix adjust.
 Identities = 69/188 (36%), Positives = 92/188 (48%), Gaps = 20/188 (10%)

Query  57   STCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEKDGVCIDINECSTNRGN-  113
            + C+D+DECA   + C  KG  CVN PGSF C C  G Y      +C+D+NEC    G  
Sbjct  352  TRCVDVDECAPPAEPCG-KGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL  410

Query  114  CDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSY  173
            C     C N  G   LC C  G+  + D    +C DINEC+ +P     +  C N+ GSY
Sbjct  411  CGHK--CENTLGS-YLCSCSVGFRLSVD--GRSCEDINECSSSPC----SQECANVYGSY  461

Query  174  KCECSAGFE-PDSSGSGCVTEDFCG--TGKNDCDTVFAACSLVPGSFKCEC-IQGFRGAG  229
            +C C  G++  D  G  C   D C   TG + C      C  +PGSF+C C   G+R A 
Sbjct  462  QCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY---RCINIPGSFQCSCPSSGYRLAP  518

Query  230  TVNTCEPL  237
                C+ +
Sbjct  519  NGRNCQDI  526


 Score = 72.4 bits (176),  Expect = 1e-12, Method: Compositional matrix adjust.
 Identities = 64/193 (33%), Positives = 98/193 (50%), Gaps = 17/193 (8%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
            F C C+ G+   GI  S  C+D++EC +     +  G  C N  GS+ C C   +R   D
Sbjct  380  FRCECKTGYYFDGI--SRMCVDVNECQRYPG--RLCGHKCENTLGSYLCSCSVGFRLSVD  435

Query  99   GV-CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP  157
            G  C DINECS++  +     +C N+ G  Q C C +G+   +D   V C DI+EC    
Sbjct  436  GRSCEDINECSSSPCS----QECANVYGSYQ-CYCRRGYQ-LSDVDGVTCEDIDECALPT  489

Query  158  SICPSNSVCTNLAGSYKCEC-SAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGS  216
                 +  C N+ GS++C C S+G+    +G  C   D C TG ++C ++   C  + G+
Sbjct  490  GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNC-SINETCFNIQGA  548

Query  217  FKC---ECIQGFR  226
            F+C   EC + +R
Sbjct  549  FRCLAFECPENYR  561


 Score = 67.8 bits (164),  Expect = 3e-11, Method: Compositional matrix adjust.
 Identities = 62/193 (32%), Positives = 89/193 (46%), Gaps = 26/193 (13%)

Query  44   CQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTC-------GCGPYRQE  96
            C+ GF    +     CIDI+EC      C   G  C+N  GS+TC       G G +  E
Sbjct  294  CKSGFIQDALG---NCIDINECLSISAPCP-IGHTCINTEGSYTCQKNVPNCGRGYHLNE  349

Query  97   KDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNEN  156
            +   C+D++EC+     C +   C+N  G  + C+C  G+    D  +  C D+NEC   
Sbjct  350  EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR-CECKTGYYF--DGISRMCVDVNECQRY  406

Query  157  P-SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDT--VFAACSLV  213
            P  +C     C N  GSY C CS GF     G  C  ED      N+C +      C+ V
Sbjct  407  PGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSC--EDI-----NECSSSPCSQECANV  457

Query  214  PGSFKCECIQGFR  226
             GS++C C +G++
Sbjct  458  YGSYQCYCRRGYQ  470


 Score = 67.8 bits (164),  Expect = 3e-11, Method: Compositional matrix adjust.
 Identities = 61/192 (31%), Positives = 82/192 (42%), Gaps = 18/192 (9%)

Query  57   STCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDGV-------CIDINECST  109
            ++C DIDEC  G+ NC      C N  GSF C   P  Q K G        CIDINEC +
Sbjct  258  NSCKDIDECESGIHNCL-PDFICQNTLGSFRCR--PKLQCKSGFIQDALGNCIDINECLS  314

Query  110  NRGNCDENSDCINLDG----EEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSV  165
                C     CIN +G    ++ +  C +G+  N +     C D++EC      C     
Sbjct  315  ISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEE--GTRCVDVDECAPPAEPCGKGHR  372

Query  166  CTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGF  225
            C N  GS++CEC  G+  D     CV  + C             C    GS+ C C  GF
Sbjct  373  CVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPG--RLCGHKCENTLGSYLCSCSVGF  430

Query  226  RGAGTVNTCEPL  237
            R +    +CE +
Sbjct  431  RLSVDGRSCEDI  442


> CE16142
Length=798

 Score = 78.6 bits (192),  Expect = 2e-14, Method: Compositional matrix adjust.
 Identities = 65/198 (32%), Positives = 96/198 (48%), Gaps = 21/198 (10%)

Query  44   CQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDG--VC  101
            C  G+   G   +  C D++EC QG+  C     +C+N+PG++ C CGP  +  D    C
Sbjct  422  CAHGYEVNGA--TGFCEDVNECQQGV--CGSM--ECINLPGTYKCKCGPGYEFNDAKKRC  475

Query  102  IDINECSTNRGN-CDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSIC  160
             D++EC    G+ CD +++CIN  G  + CKC  G+   +D     C D+NEC    + C
Sbjct  476  EDVDECIKFAGHVCDLSAECINTIGSFE-CKCKPGFQLASD--GRRCEDVNECTTGIAAC  532

Query  161  PSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFC----GTGKNDCDTVFAACSLVPGS  216
                 C N+ GSY+C C  GF     G+ C   D C    G+G + C      C    GS
Sbjct  533  EQK--CVNIPGSYQCICDRGFALGPDGTKCEDIDECSIWAGSGNDLC---MGGCINTKGS  587

Query  217  FKCECIQGFRGAGTVNTC  234
            + C+C  G++      TC
Sbjct  588  YLCQCPPGYKIQPDGRTC  605


 Score = 77.0 bits (188),  Expect = 6e-14, Method: Compositional matrix adjust.
 Identities = 64/172 (37%), Positives = 88/172 (51%), Gaps = 19/172 (11%)

Query  62   IDECAQGLDNCKQKGGDCVNIPGSFTC-------GCGPYRQEKDGVCIDINECSTNRGNC  114
            IDEC  G  NC   G +CVN PGSF C         G       G C D+NEC   +G C
Sbjct  391  IDECVTG-HNCG-AGEECVNTPGSFRCQQKGNLCAHGYEVNGATGFCEDVNECQ--QGVC  446

Query  115  DENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP-SICPSNSVCTNLAGSY  173
              + +CINL G  + CKC  G+  N+ K    C D++EC +    +C  ++ C N  GS+
Sbjct  447  G-SMECINLPGTYK-CKCGPGYEFNDAKKR--CEDVDECIKFAGHVCDLSAECINTIGSF  502

Query  174  KCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGF  225
            +C+C  GF+  S G  C   + C TG   C+     C  +PGS++C C +GF
Sbjct  503  ECKCKPGFQLASDGRRCEDVNECTTGIAACEQ---KCVNIPGSYQCICDRGF  551


 Score = 72.8 bits (177),  Expect = 9e-13, Method: Compositional matrix adjust.
 Identities = 61/189 (32%), Positives = 87/189 (46%), Gaps = 17/189 (8%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
            + C C  G+  +  +    C D+DEC +   +      +C+N  GSF C C P ++   D
Sbjct  458  YKCKCGPGY--EFNDAKKRCEDVDECIKFAGHVCDLSAECINTIGSFECKCKPGFQLASD  515

Query  99   GV-CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECN---  154
            G  C D+NEC+T    C++   C+N+ G  Q C C +G+    D     C DI+EC+   
Sbjct  516  GRRCEDVNECTTGIAACEQK--CVNIPGSYQ-CICDRGFALGPD--GTKCEDIDECSIWA  570

Query  155  -ENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLV  213
                 +C     C N  GSY C+C  G++    G  CV  D C  G  +C      C   
Sbjct  571  GSGNDLCMGG--CINTKGSYLCQCPPGYKIQPDGRTCVDVDECAMG--ECAGSDKVCVNT  626

Query  214  PGSFKCECI  222
             GSFKC  I
Sbjct  627  LGSFKCHSI  635


 Score = 51.6 bits (122),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 73/289 (25%), Positives = 103/289 (35%), Gaps = 93/289 (32%)

Query  26   SRVEHAESCQSGDGFWCACQKGF--TPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIP  83
            S  EH    + G+   C+C+ GF   P G+     C+D +EC      C Q   DCVN  
Sbjct  162  SHCEHLCHDRGGEKVECSCRSGFDLAPDGM----ACVDRNECLTRQSPCTQ-SEDCVNTI  216

Query  84   GSFTC-----------------GCGPYRQEKD----------------------------  98
            G + C                 G  P R   D                            
Sbjct  217  GGYICQRRISRLVPHRHRANRIGNAPRRMRDDPYSRAGEYREASQANTEFGCPMGWLFQH  276

Query  99   GVCIDINECSTNRGNCDENSDCINLDGEEQLCK---CHKGWTGNNDKPNVAC--------  147
            G C+DI+EC+T   +C E+  C+N  G  +  +   C  G+  +++     C        
Sbjct  277  GHCVDIDECATLMDDCLESQRCLNTPGSFKCIRTLSCGTGYAMDSETERNNCFLIILNNT  336

Query  148  --------RDINECNENPSICPSNSVCTNLAGSYKCE---CSAGFEPDSSGSG-----CV  191
                     D++ECN     C     C N  GSY+C+   C  G E  +  +G     CV
Sbjct  337  FNCKYFFVEDVDECNLGSHDCGPLYQCRNTQGSYRCDAKKCGDG-ELQNPMTGEYIDECV  395

Query  192  TEDFCGTGKNDCDTVFAACSLVPGSFKCE-----CIQGFRGAGTVNTCE  235
            T   CG G+         C   PGSF+C+     C  G+   G    CE
Sbjct  396  TGHNCGAGEE--------CVNTPGSFRCQQKGNLCAHGYEVNGATGFCE  436


 Score = 47.8 bits (112),  Expect = 3e-05, Method: Compositional matrix adjust.
 Identities = 63/237 (26%), Positives = 96/237 (40%), Gaps = 45/237 (18%)

Query  29   EHAESCQSGDGFWCACQKGFTPQG-INLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFT  87
            E+ E+ Q+   F C       P G +     C+DIDECA  +D+C +    C+N PGSF 
Sbjct  255  EYREASQANTEFGC-------PMGWLFQHGHCVDIDECATLMDDCLE-SQRCLNTPGSFK  306

Query  88   C----GCGP-YRQE-------------------KDGVCIDINECSTNRGNCDENSDCINL  123
            C     CG  Y  +                   K     D++EC+    +C     C N 
Sbjct  307  CIRTLSCGTGYAMDSETERNNCFLIILNNTFNCKYFFVEDVDECNLGSHDCGPLYQCRNT  366

Query  124  DGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCE-----CS  178
             G  + C   K   G    P      I+EC    + C +   C N  GS++C+     C+
Sbjct  367  QGSYR-CDAKKCGDGELQNPMTG-EYIDECVTGHN-CGAGEECVNTPGSFRCQQKGNLCA  423

Query  179  AGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCE  235
             G+E + +   C   + C  G   C ++   C  +PG++KC+C  G+        CE
Sbjct  424  HGYEVNGATGFCEDVNECQQGV--CGSM--ECINLPGTYKCKCGPGYEFNDAKKRCE  476


 Score = 44.3 bits (103),  Expect = 4e-04, Method: Compositional matrix adjust.
 Identities = 59/180 (32%), Positives = 79/180 (43%), Gaps = 32/180 (17%)

Query  40   FWCACQKGFT--PQGINLSSTCIDIDECA----QGLDNCKQKGGDCVNIPGSFTCGCGP-  92
            + C C +GF   P G    + C DIDEC+     G D C    G C+N  GS+ C C P 
Sbjct  543  YQCICDRGFALGPDG----TKCEDIDECSIWAGSGNDLCM---GGCINTKGSYLCQCPPG  595

Query  93   YRQEKDG-VCIDINECSTNRGNCD-ENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRD-  149
            Y+ + DG  C+D++EC+   G C   +  C+N  G     KCH     + D P     D 
Sbjct  596  YKIQPDGRTCVDVDECAM--GECAGSDKVCVNTLGSF---KCH-----SIDCPTNYIHDS  645

Query  150  --INECNENPSICPSNSVCTN--LAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDT  205
               N CN  PS C     C+   L  +Y+    A   P SS    +T  F  +  N  DT
Sbjct  646  LNKNRCNRQPSACGLPEECSKVPLFLTYQFISLARAVPISSHRPAITL-FKVSAPNHADT  704


> Hs13518039
Length=937

 Score = 77.0 bits (188),  Expect = 5e-14, Method: Compositional matrix adjust.
 Identities = 73/254 (28%), Positives = 104/254 (40%), Gaps = 57/254 (22%)

Query  25   CSRVEH--AESCQSGDG-FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVN  81
            CS +EH  A  C +  G + C C++G+        +TC   D CA    NC+Q    CVN
Sbjct  242  CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQ--TTCRIQDLCAMEDHNCEQL---CVN  296

Query  82   IPGSFTCGCGP-YRQEKDG-VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGN  139
            +PGSF C C   Y   +DG  C+ ++ C++    C+   +C+N DG   LC+CH+G+  N
Sbjct  297  VPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEH--ECVNADGS-YLCQCHEGFALN  353

Query  140  NDKP---------------------------------------NVACRDINECNENPSIC  160
             D+                                           CR IN C  N   C
Sbjct  354  PDEKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGC  413

Query  161  PSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCE  220
                 C N+  SY C C  G+  D +G  C   D C    + C+ +   C     SF C+
Sbjct  414  EHE--CVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQL---CLNTEDSFVCQ  468

Query  221  CIQGFRGAGTVNTC  234
            C +GF     + TC
Sbjct  469  CSEGFLINEDLKTC  482


 Score = 61.6 bits (148),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 54/195 (27%), Positives = 86/195 (44%), Gaps = 21/195 (10%)

Query  38   DGFWCACQKGFT--PQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPY  93
            + ++C C +G+T  P G     TC  +D CAQ    C+Q    C+N   SF C C  G  
Sbjct  422  ESYYCRCHRGYTLDPNG----KTCSRVDHCAQQDHGCEQL---CLNTEDSFVCQCSEGFL  474

Query  94   RQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINEC  153
              E    C  ++ C  +   C+ +  C+N+D     C+C +G    +D     C  ++ C
Sbjct  475  INEDLKTCSRVDYCLLSDHGCEYS--CVNMD-RSFACQCPEGHVLRSDGK--TCAKLDSC  529

Query  154  NENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLV  213
                  C  +  C +   S+ C+C  G+     G  C  +D C    + C+ +   C   
Sbjct  530  ALGDHGCEHS--CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHI---CVNS  584

Query  214  PGSFKCECIQGFRGA  228
              S+ CEC++GFR A
Sbjct  585  DDSYTCECLEGFRLA  599


 Score = 59.3 bits (142),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 58/209 (27%), Positives = 91/209 (43%), Gaps = 22/209 (10%)

Query  23   DHCSRVEHA--ESC-QSGDGFWCACQKGFTPQGINLS-STCIDIDECAQGLDNCKQKGGD  78
            DHC++ +H   + C  + D F C C +GF    IN    TC  +D C      C+     
Sbjct  445  DHCAQQDHGCEQLCLNTEDSFVCQCSEGFL---INEDLKTCSRVDYCLLSDHGCEY---S  498

Query  79   CVNIPGSFTCGC--GPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGW  136
            CVN+  SF C C  G   +     C  ++ C+     C+ +  C++ + +  +C+C +G+
Sbjct  499  CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHS--CVSSE-DSFVCQCFEGY  555

Query  137  TGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFC  196
                D     CR  + C      C    +C N   SY CEC  GF     G  C  +D C
Sbjct  556  ILREDGK--TCRRKDVCQAIDHGC--EHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVC  611

Query  197  GTGKNDCDTVFAACSLVPGSFKCECIQGF  225
             +  + C+ +   C     S+ C+C +GF
Sbjct  612  KSTHHGCEHI---CVNNGNSYICKCSEGF  637


 Score = 42.4 bits (98),  Expect = 0.001, Method: Compositional matrix adjust.
 Identities = 54/180 (30%), Positives = 72/180 (40%), Gaps = 29/180 (16%)

Query  25   CSRVEH--------AESCQSGD-GFWCACQKGFTPQGINLSS---TCIDIDECAQGLDNC  72
            CSRV++          SC + D  F C C     P+G  L S   TC  +D CA G   C
Sbjct  482  CSRVDYCLLSDHGCEYSCVNMDRSFACQC-----PEGHVLRSDGKTCAKLDSCALGDHGC  536

Query  73   KQKGGDCVNIPGSFTCGC--GPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLC  130
            +     CV+   SF C C  G   +E    C   + C      C+    C+N D +   C
Sbjct  537  EH---SCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHI--CVNSD-DSYTC  590

Query  131  KCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGC  190
            +C +G+    D     CR  + C      C    +C N   SY C+CS GF     G  C
Sbjct  591  ECLEGFRLAEDGKR--CRRKDVCKSTHHGC--EHICVNNGNSYICKCSEGFVLAEDGRRC  646


> Hs13518037
Length=956

 Score = 77.0 bits (188),  Expect = 5e-14, Method: Compositional matrix adjust.
 Identities = 73/254 (28%), Positives = 104/254 (40%), Gaps = 57/254 (22%)

Query  25   CSRVEH--AESCQSGDG-FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVN  81
            CS +EH  A  C +  G + C C++G+        +TC   D CA    NC+Q    CVN
Sbjct  242  CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQ--TTCRIQDLCAMEDHNCEQL---CVN  296

Query  82   IPGSFTCGCGP-YRQEKDG-VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGN  139
            +PGSF C C   Y   +DG  C+ ++ C++    C+   +C+N DG   LC+CH+G+  N
Sbjct  297  VPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEH--ECVNADGS-YLCQCHEGFALN  353

Query  140  NDKP---------------------------------------NVACRDINECNENPSIC  160
             D+                                           CR IN C  N   C
Sbjct  354  PDEKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGC  413

Query  161  PSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCE  220
                 C N+  SY C C  G+  D +G  C   D C    + C+ +   C     SF C+
Sbjct  414  EHE--CVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQL---CLNTEDSFVCQ  468

Query  221  CIQGFRGAGTVNTC  234
            C +GF     + TC
Sbjct  469  CSEGFLINEDLKTC  482


 Score = 61.6 bits (148),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 54/195 (27%), Positives = 86/195 (44%), Gaps = 21/195 (10%)

Query  38   DGFWCACQKGFT--PQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPY  93
            + ++C C +G+T  P G     TC  +D CAQ    C+Q    C+N   SF C C  G  
Sbjct  422  ESYYCRCHRGYTLDPNG----KTCSRVDHCAQQDHGCEQL---CLNTEDSFVCQCSEGFL  474

Query  94   RQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINEC  153
              E    C  ++ C  +   C+ +  C+N+D     C+C +G    +D     C  ++ C
Sbjct  475  INEDLKTCSRVDYCLLSDHGCEYS--CVNMD-RSFACQCPEGHVLRSDGK--TCAKLDSC  529

Query  154  NENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLV  213
                  C  +  C +   S+ C+C  G+     G  C  +D C    + C+ +   C   
Sbjct  530  ALGDHGCEHS--CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHI---CVNS  584

Query  214  PGSFKCECIQGFRGA  228
              S+ CEC++GFR A
Sbjct  585  DDSYTCECLEGFRLA  599


 Score = 59.3 bits (142),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 58/209 (27%), Positives = 91/209 (43%), Gaps = 22/209 (10%)

Query  23   DHCSRVEHA--ESC-QSGDGFWCACQKGFTPQGINLS-STCIDIDECAQGLDNCKQKGGD  78
            DHC++ +H   + C  + D F C C +GF    IN    TC  +D C      C+     
Sbjct  445  DHCAQQDHGCEQLCLNTEDSFVCQCSEGFL---INEDLKTCSRVDYCLLSDHGCEY---S  498

Query  79   CVNIPGSFTCGC--GPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGW  136
            CVN+  SF C C  G   +     C  ++ C+     C+ +  C++ + +  +C+C +G+
Sbjct  499  CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHS--CVSSE-DSFVCQCFEGY  555

Query  137  TGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFC  196
                D     CR  + C      C    +C N   SY CEC  GF     G  C  +D C
Sbjct  556  ILREDGK--TCRRKDVCQAIDHGC--EHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVC  611

Query  197  GTGKNDCDTVFAACSLVPGSFKCECIQGF  225
             +  + C+ +   C     S+ C+C +GF
Sbjct  612  KSTHHGCEHI---CVNNGNSYICKCSEGF  637


 Score = 42.4 bits (98),  Expect = 0.001, Method: Compositional matrix adjust.
 Identities = 54/180 (30%), Positives = 72/180 (40%), Gaps = 29/180 (16%)

Query  25   CSRVEH--------AESCQSGD-GFWCACQKGFTPQGINLSS---TCIDIDECAQGLDNC  72
            CSRV++          SC + D  F C C     P+G  L S   TC  +D CA G   C
Sbjct  482  CSRVDYCLLSDHGCEYSCVNMDRSFACQC-----PEGHVLRSDGKTCAKLDSCALGDHGC  536

Query  73   KQKGGDCVNIPGSFTCGC--GPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLC  130
            +     CV+   SF C C  G   +E    C   + C      C+    C+N D +   C
Sbjct  537  EH---SCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEH--ICVNSD-DSYTC  590

Query  131  KCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGC  190
            +C +G+    D     CR  + C      C    +C N   SY C+CS GF     G  C
Sbjct  591  ECLEGFRLAEDGKR--CRRKDVCKSTHHGC--EHICVNNGNSYICKCSEGFVLAEDGRRC  646


> Hs19743803
Length=448

 Score = 75.5 bits (184),  Expect = 1e-13, Method: Compositional matrix adjust.
 Identities = 64/199 (32%), Positives = 92/199 (46%), Gaps = 25/199 (12%)

Query  44   CQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDGVCID  103
            C+ G+    ++ S+ C+D+DECA     C      C+N  G +TC C       +G C+D
Sbjct  113  CRFGYQ---MDESNQCVDVDECATDSHQCN-PTQICINTEGGYTCSCTDGYWLLEGQCLD  168

Query  104  INECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINEC-NENPSICPS  162
            I+EC    G C +   C N+ G    C C+ G+T N D    +C+D+NEC  ENP +   
Sbjct  169  IDECRY--GYCQQL--CANVPGSYS-CTCNPGFTLNED--GRSCQDVNECATENPCV---  218

Query  163  NSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECI  222
               C N  GS+ C C  G+E +  G  C   D C   +  C      C   PG++ C C 
Sbjct  219  -QTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQ---HECVNQPGTYFCSCP  274

Query  223  QGF------RGAGTVNTCE  235
             G+      R    +N CE
Sbjct  275  PGYILLDDNRSCQDINECE  293


 Score = 68.6 bits (166),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 62/200 (31%), Positives = 89/200 (44%), Gaps = 34/200 (17%)

Query  25   CSRVEHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPG  84
            C   E   +C   DG+W             L   C+DIDEC  G   C+Q    C N+PG
Sbjct  144  CINTEGGYTCSCTDGYWL------------LEGQCLDIDECRYGY--CQQL---CANVPG  186

Query  85   SFTCGCGP-YRQEKDGV-CIDINECSTNRGNCDEN---SDCINLDGEEQLCKCHKGWTGN  139
            S++C C P +   +DG  C D+NEC+T      EN     C+N  G   +C+C  G+   
Sbjct  187  SYSCTCNPGFTLNEDGRSCQDVNECAT------ENPCVQTCVNTYGSF-ICRCDPGYELE  239

Query  140  NDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTG  199
             D   V C D++EC+ +  +C     C N  G+Y C C  G+        C   + C   
Sbjct  240  ED--GVHCSDMDECSFSEFLC--QHECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHR  295

Query  200  KNDCDTVFAACSLVPGSFKC  219
             + C+ +   C  + G FKC
Sbjct  296  NHTCN-LQQTCYNLQGGFKC  314


 Score = 34.7 bits (78),  Expect = 0.32, Method: Compositional matrix adjust.
 Identities = 42/170 (24%), Positives = 63/170 (37%), Gaps = 48/170 (28%)

Query  96   EKDGVCIDINECSTNRGNCDENSDCINLDGEEQLC-----KCHKGWTGN-----------  139
             + G C+DI+EC T    C  +  C+N +G   LC       ++G   N           
Sbjct  35   RQSGQCLDIDECRTIPEACRGDMMCVNQNG-GYLCIPRTNPVYRGPYSNPYSTPYSGPYP  93

Query  140  --------NDKPNVA----------------CRDINECNENPSICPSNSVCTNLAGSYKC  175
                     + P ++                C D++EC  +   C    +C N  G Y C
Sbjct  94   AAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTC  153

Query  176  ECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGF  225
             C+ G+        C+  D C  G   C  +   C+ VPGS+ C C  GF
Sbjct  154  SCTDGYW--LLEGQCLDIDECRYGY--CQQL---CANVPGSYSCTCNPGF  196


> Hs10190748
Length=999

 Score = 75.1 bits (183),  Expect = 2e-13, Method: Compositional matrix adjust.
 Identities = 64/179 (35%), Positives = 82/179 (45%), Gaps = 15/179 (8%)

Query  61   DIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDGVCIDINECSTNRGNCDENSDC  120
            D+DECAQGLD+C      C N P S+ C C P  Q +   C DI+EC  N  N     DC
Sbjct  45   DVDECAQGLDDC-HADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECG-NELNGGCVHDC  102

Query  121  INLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAG  180
            +N+ G  + C C  G+   +D  N  C D++EC EN   C     C N+ GSY+C C  G
Sbjct  103  LNIPGNYR-CTCFDGFMLAHDGHN--CLDVDECLENNGGC--QHTCVNVMGSYECCCKEG  157

Query  181  FEPDSSGSGCVTED----FCGTGKNDCDTVFAACSLVP-GSFKCECIQGFRGAGTVNTC  234
            F    +   C+        C    + C  +   C   P GS  CEC  GF  A     C
Sbjct  158  FFLSDNQHTCIHRSEEGLSCMNKDHGCSHI---CKEAPRGSVACECRPGFELAKNQRDC  213


 Score = 65.1 bits (157),  Expect = 2e-10, Method: Compositional matrix adjust.
 Identities = 59/155 (38%), Positives = 74/155 (47%), Gaps = 16/155 (10%)

Query  39   GFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQE  96
            G  C+C  GFT Q      TC DIDEC      C      C NI GSF CGC  G     
Sbjct  303  GVHCSCPVGFTLQLD--GKTCKDIDECQTRNGGCDHF---CKNIVGSFDCGCKKGFKLLT  357

Query  97   KDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNEN  156
             +  C D++ECS +R  CD +  CIN  G    C C++G+T         C D NEC+ N
Sbjct  358  DEKSCQDVDECSLDR-TCDHS--CINHPGT-FACACNRGYTLYG---FTHCGDTNECSIN  410

Query  157  PSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCV  191
               C    VC N  GSY+C+C  G++   +   CV
Sbjct  411  NGGC--QQVCVNTVGSYECQCHPGYKLHWNKKDCV  443


 Score = 55.8 bits (133),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 61/201 (30%), Positives = 94/201 (46%), Gaps = 32/201 (15%)

Query  3    PPRLAAMGGKSSTPCDAGGYDHCSRVEHAES-CQ-SGDGFWCACQKGFTPQGINLSSTCI  60
            P R  A G +      A G D C    HA++ CQ +   + C+C+ G+  +G      C 
Sbjct  34   PGRGRAAGPQEDVDECAQGLDDC----HADALCQNTPTSYKCSCKPGYQGEG----RQCE  85

Query  61   DIDECAQGLDNCKQKGG---DCVNIPGSFTCGC-GPYRQEKDGV-CIDINECSTNRGNCD  115
            DIDEC   L+     GG   DC+NIPG++ C C   +    DG  C+D++EC  N G C 
Sbjct  86   DIDECGNELN-----GGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQ  140

Query  116  ENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNL-----A  170
                C+N+ G  + C C +G+  ++++       I+   E  S    +  C+++      
Sbjct  141  HT--CVNVMGSYECC-CKEGFFLSDNQHTC----IHRSEEGLSCMNKDHGCSHICKEAPR  193

Query  171  GSYKCECSAGFEPDSSGSGCV  191
            GS  CEC  GFE   +   C+
Sbjct  194  GSVACECRPGFELAKNQRDCI  214


 Score = 42.7 bits (99),  Expect = 0.001, Method: Compositional matrix adjust.
 Identities = 40/140 (28%), Positives = 64/140 (45%), Gaps = 12/140 (8%)

Query  87   TCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVA  146
            +C  G   Q     C DI+EC T  G CD    C N+ G    C C KG+    D+   +
Sbjct  307  SCPVGFTLQLDGKTCKDIDECQTRNGGCDHF--CKNIVGSFD-CGCKKGFKLLTDEK--S  361

Query  147  CRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTV  206
            C+D++EC+ + +    +  C N  G++ C C+ G+      + C   + C      C  V
Sbjct  362  CQDVDECSLDRTC---DHSCINHPGTFACACNRGYTL-YGFTHCGDTNECSINNGGCQQV  417

Query  207  FAACSLVPGSFKCECIQGFR  226
               C    GS++C+C  G++
Sbjct  418  ---CVNTVGSYECQCHPGYK  434


 Score = 41.6 bits (96),  Expect = 0.002, Method: Compositional matrix adjust.
 Identities = 40/136 (29%), Positives = 55/136 (40%), Gaps = 16/136 (11%)

Query  104  INECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSN  163
            +  C+ N G CD      +       C C  G+T   D     C+DI+EC      C  +
Sbjct  283  METCAVNNGGCDRTCKDTSTGVH---CSCPVGFTLQLD--GKTCKDIDECQTRNGGC--D  335

Query  164  SVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCEC--  221
              C N+ GS+ C C  GF+  +    C   D C   +  CD    +C   PG+F C C  
Sbjct  336  HFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRT-CD---HSCINHPGTFACACNR  391

Query  222  ---IQGFRGAGTVNTC  234
               + GF   G  N C
Sbjct  392  GYTLYGFTHCGDTNEC  407


> Hs22044235
Length=1229

 Score = 75.1 bits (183),  Expect = 2e-13, Method: Compositional matrix adjust.
 Identities = 66/203 (32%), Positives = 89/203 (43%), Gaps = 23/203 (11%)

Query  42   CACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC-GPYRQEKDGV  100
            C C  G+  Q       C D+DECA GL  C      C+N  GSF C C   Y    DG 
Sbjct  163  CECHVGY--QLAADGKACEDVDECAAGLAQCAH---GCLNTQGSFKCVCHAGYELGADGR  217

Query  101  -CIDI-----NECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECN  154
             C  I     N C  N G C       +      LC C +G+  + D+    C D+++C 
Sbjct  218  QCYRIEMEIVNSCEANNGGCSHG---CSHTSAGPLCTCPRGYELDTDQ--RTCIDVDDCA  272

Query  155  ENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVP  214
            ++P       VCTN  G Y+C C AG+   + G GC   D C + +  C+     C+ + 
Sbjct  273  DSPCC---QQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEH---HCTNLA  326

Query  215  GSFKCECIQGFRGAGTVNTCEPL  237
            GSF+C C  G+R       C PL
Sbjct  327  GSFQCSCEAGYRLHEDRRGCSPL  349


 Score = 62.0 bits (149),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 52/167 (31%), Positives = 70/167 (41%), Gaps = 14/167 (8%)

Query  61   DIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKDG-VCIDINECSTNRGNCDENS  118
            D+DEC      C+ +   CVN PGS+ C C P +R   D   C+ IN C+   G C  + 
Sbjct  56   DVDECRTHNGGCQHR---CVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHH-  111

Query  119  DCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECS  178
             C+ L      C+C  G+    D  +   R     N N S       C  + G  +CEC 
Sbjct  112  -CVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCA-NRNGSC---MHRCQVVRGLARCECH  166

Query  179  AGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGF  225
             G++  + G  C   D C  G   C      C    GSFKC C  G+
Sbjct  167  VGYQLAADGKACEDVDECAAGLAQC---AHGCLNTQGSFKCVCHAGY  210


 Score = 36.2 bits (82),  Expect = 0.11, Method: Compositional matrix adjust.
 Identities = 26/95 (27%), Positives = 37/95 (38%), Gaps = 4/95 (4%)

Query  132  CHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCV  191
            CH G  G          D++EC  +   C     C N  GSY CEC  GF   +    C+
Sbjct  39   CHLGQAGYPVSAGDQRPDVDECRTHNGGC--QHRCVNTPGSYLCECKPGFRLHTDSRTCL  96

Query  192  TEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFR  226
              + C  G   C       ++     +C+C  GF+
Sbjct  97   AINSCALGNGGCQHHCVQLTIT--RHRCQCRPGFQ  129


> Hs4505395
Length=1247

 Score = 74.7 bits (182),  Expect = 3e-13, Method: Compositional matrix adjust.
 Identities = 64/199 (32%), Positives = 91/199 (45%), Gaps = 30/199 (15%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKD  98
            F C C  GF   G     TC DIDEC++    C      C N PG+F C C   Y+   +
Sbjct  693  FTCECSIGFRGDG----RTCYDIDECSEQPSVCGSHT-ICNNHPGTFRCECVEGYQFSDE  747

Query  99   GVCI------DINECSTNRGNCD--ENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDI  150
            G C+       IN C T   NCD  + + CI   G    C C  G++G+      AC+D+
Sbjct  748  GTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDGQ----ACQDV  803

Query  151  NECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTG-KNDCDTVFAA  209
            +EC   PS C  ++ C N  GS+ C+C  G++ D  G  CV  +   T  +++ + +  A
Sbjct  804  DECQ--PSRCHPDAFCYNTPGSFTCQCKPGYQGD--GFRCVPGEVEKTRCQHEREHILGA  859

Query  210  C-------SLVPGSFKCEC  221
                     + PG F  EC
Sbjct  860  AGATDPQRPIPPGLFVPEC  878


 Score = 71.6 bits (174),  Expect = 2e-12, Method: Compositional matrix adjust.
 Identities = 50/163 (30%), Positives = 78/163 (47%), Gaps = 17/163 (10%)

Query  85   SFTCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPN  144
            +F+   GP R+         N C      CD N+ C      +  C+C  G+ G+     
Sbjct  652  AFSNSIGPVREGSPDALQ--NPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGR---  706

Query  145  VACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTED-----FCGTG  199
              C DI+EC+E PS+C S+++C N  G+++CEC  G++    G+     D     +C TG
Sbjct  707  -TCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETG  765

Query  200  KNDCDTVFAACSLVPG--SFKCECIQGFRGAGT----VNTCEP  236
             ++CD    A  +  G  S+ C C+ GF G G     V+ C+P
Sbjct  766  LHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDGQACQDVDECQP  808


> Hs5453764
Length=810

 Score = 70.9 bits (172),  Expect = 4e-12, Method: Compositional matrix adjust.
 Identities = 67/194 (34%), Positives = 90/194 (46%), Gaps = 24/194 (12%)

Query  42   CACQKGF-TPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKDG  99
            C C+ G+ + QG   S+ C DIDECA  +  C      CVN+PG + C C P Y +  D 
Sbjct  416  CECKSGYISVQGD--SAYCEDIDECAAKMHYC-HANTVCVNLPGLYRCDCVPGYIRVDDF  472

Query  100  VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSI  159
             C + +EC + + NCDEN+ C N   +   C C  G+ GN       CR    C E    
Sbjct  473  SCTEHDECGSGQHNCDENAICTNT-VQGHSCTCKPGYVGNG----TICRAF--CEEG---  522

Query  160  CPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTE-DFCGTGKNDCDTVFAACSLVPGSFK  218
            C     C       KC C +GF    +GS C  + D C  G  +C    + C  +PG + 
Sbjct  523  CRYGGTC---VAPNKCVCPSGF----TGSHCEKDIDECSEGIIECHN-HSRCVNLPGWYH  574

Query  219  CECIQGFRGAGTVN  232
            CEC  GF   GT +
Sbjct  575  CECRSGFHDDGTYS  588


 Score = 62.8 bits (151),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 47/144 (32%), Positives = 69/144 (47%), Gaps = 12/144 (8%)

Query  96   EKDGVCIDINECSTNRGN--------CDENSDCINLDGEEQLCKCHKGWTGNNDKPNVAC  147
            EKD +  +   C   RG+        C ENS+C N +  +  C+C  G+       +  C
Sbjct  375  EKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWN-TKATCECKSGYISVQGD-SAYC  432

Query  148  RDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVF  207
             DI+EC      C +N+VC NL G Y+C+C  G+      S C   D CG+G+++CD   
Sbjct  433  EDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFS-CTEHDECGSGQHNCDE-N  490

Query  208  AACSLVPGSFKCECIQGFRGAGTV  231
            A C+       C C  G+ G GT+
Sbjct  491  AICTNTVQGHSCTCKPGYVGNGTI  514


 Score = 47.0 bits (110),  Expect = 6e-05, Method: Compositional matrix adjust.
 Identities = 38/101 (37%), Positives = 48/101 (47%), Gaps = 10/101 (9%)

Query  32   ESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC-  90
            E C+ G G   A  K   P G   S    DIDEC++G+  C      CVN+PG + C C 
Sbjct  521  EGCRYG-GTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNH-SRCVNLPGWYHCECR  578

Query  91   ------GPYRQEKDGVCIDINECSTNRGNCDENSDCINLDG  125
                  G Y    +  CIDI+EC+     C  +S CINL G
Sbjct  579  SGFHDDGTYSLSGES-CIDIDECALRTHTCWNDSACINLAG  618


> Hs13124888
Length=553

 Score = 68.2 bits (165),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 66/204 (32%), Positives = 91/204 (44%), Gaps = 24/204 (11%)

Query  42   CACQKGFTPQGINLSSTC-IDIDECAQGLDNCKQKGGDCVNIPGSFTCGC-GPYRQEKDG  99
            C C  G+T        TC  D++EC      C+ +   CVN  GS+ C C   +    D 
Sbjct  80   CRCFPGYT------GKTCSQDVNECGMKPRPCQHR---CVNTHGSYKCFCLSGHMLMPDA  130

Query  100  VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPN-VACRDINECNENPS  158
             C++   C+    NC  + +    +G + LC      +G    PN   C DI+EC     
Sbjct  131  TCVNSRTCAMI--NCQYSCEDTE-EGPQCLCPS----SGLRLAPNGRDCLDIDECASGKV  183

Query  159  ICPSNSVCTNLAGSYKCECSAGFEPD--SSGSGCVTEDFCGTGKNDCDTVFAACSLVPGS  216
            ICP N  C N  GSY C+C  GFE    S    C+  + C    + C +  A C    GS
Sbjct  184  ICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTC-SHHANCFNTQGS  242

Query  217  FKCECIQGFRGAGTVNTCEPLPGN  240
            FKC+C QG++G G    C  +P N
Sbjct  243  FKCKCKQGYKGNGL--RCSAIPEN  264


 Score = 40.0 bits (92),  Expect = 0.007, Method: Compositional matrix adjust.
 Identities = 20/51 (39%), Positives = 25/51 (49%), Gaps = 1/51 (1%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC  90
            ++C C  GF  Q I+    CIDI+EC      C     +C N  GSF C C
Sbjct  198  YYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHH-ANCFNTQGSFKCKC  247


>
Length=1394

 Score = 68.2 bits (165),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 75/247 (30%), Positives = 102/247 (41%), Gaps = 53/247 (21%)

Query  39   GFWCACQKGF--TPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQ  95
            GF CAC+ GF  TP G      C DIDEC+Q   NC      C+N+ G+  C C   Y  
Sbjct  664  GFACACETGFELTPDGFG----CADIDECSQDYGNCSDI---CINLLGTHACACERGYEL  716

Query  96   EKDGV-CIDINECS-TNRGNCDENSDCINLDGEEQLCKCHKGWTGNND----KPNVA---  146
             KD + C+D++EC+    G C  + +CIN  G  + C C  G+  N+D     P +    
Sbjct  717  AKDKLSCLDVDECAGLLSGGC--SHECINKAGTFE-CGCPLGYILNDDGRSCSPALVGCP  773

Query  147  --------------------------CRDINECNENPSICPSNSVCTNLAGSYKCECSAG  180
                                      C DI+EC +    C  +  C+N  GS+KC C  G
Sbjct  774  PGTQRSADGCAPIECNPGYTLGSDDKCVDIDECQKQNGGC--SHRCSNTEGSFKCSCPPG  831

Query  181  FEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCEPLPGN  240
            +E DS    C   D C   K  C  +   C    G F+CE    F     + T   LP +
Sbjct  832  YELDSDQKTCQDIDECDQDKTSC--ITGTCINEIGGFRCE-FPKFPVLPEIPTASSLPES  888

Query  241  EDLACTT  247
              +   T
Sbjct  889  PKIELKT  895


 Score = 67.0 bits (162),  Expect = 5e-11, Method: Compositional matrix adjust.
 Identities = 76/237 (32%), Positives = 95/237 (40%), Gaps = 57/237 (24%)

Query  39   GFWCACQKGFTPQGINLSS---TCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YR  94
            GF CAC     P G  LS    TC DIDEC      C Q    C+N PG F C C   + 
Sbjct  623  GFQCAC-----PLGYALSEDMRTCQDIDECLDSNGQCSQL---CLNQPGGFACACETGFE  674

Query  95   QEKDGV-CIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINEC  153
               DG  C DI+ECS + GNC +   CINL G    C C +G+    DK  ++C D++EC
Sbjct  675  LTPDGFGCADIDECSQDYGNCSD--ICINLLGT-HACACERGYELAKDK--LSCLDVDEC  729

Query  154  NENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGC-----------------------  190
                S   S+  C N AG+++C C  G+  +  G  C                       
Sbjct  730  AGLLSGGCSHE-CINKAGTFECGCPLGYILNDDGRSCSPALVGCPPGTQRSADGCAPIEC  788

Query  191  ------------VTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTCE  235
                        V  D C      C      CS   GSFKC C  G+       TC+
Sbjct  789  NPGYTLGSDDKCVDIDECQKQNGGCS---HRCSNTEGSFKCSCPPGYELDSDQKTCQ  842


 Score = 66.2 bits (160),  Expect = 9e-11, Method: Compositional matrix adjust.
 Identities = 65/220 (29%), Positives = 92/220 (41%), Gaps = 36/220 (16%)

Query  40   FWCACQKGFTPQGIN-LSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEK  97
            + C C  G+    ++ +   C DIDEC+Q    C  +   C N+ GS+TC C P Y    
Sbjct  515  YGCICAAGYELLKLDGIRGYCFDIDECSQRTHGCSDQML-CENLNGSYTCLCPPGYALGL  573

Query  98   DG-----------------------VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHK  134
            D                         C+DI+ECS   GNC     C N  G  Q C C  
Sbjct  574  DNHIVTSLNSSFITDSTSSETPSAHTCLDIDECSLANGNCSHF--CQNEPGGFQ-CACPL  630

Query  135  GWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTED  194
            G+  + D     C+DI+EC ++   C  + +C N  G + C C  GFE    G GC   D
Sbjct  631  GYALSEDM--RTCQDIDECLDSNGQC--SQLCLNQPGGFACACETGFELTPDGFGCADID  686

Query  195  FCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTC  234
             C     +C  +   C  + G+  C C +G+  A    +C
Sbjct  687  ECSQDYGNCSDI---CINLLGTHACACERGYELAKDKLSC  723


 Score = 62.4 bits (150),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 59/184 (32%), Positives = 81/184 (44%), Gaps = 16/184 (8%)

Query  56   SSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEKDGVCIDINECSTNRGN  113
            + TC+DIDEC+    NC      C N PG F C C  G    E    C DI+EC  + G 
Sbjct  597  AHTCLDIDECSLANGNCSHF---CQNEPGGFQCACPLGYALSEDMRTCQDIDECLDSNGQ  653

Query  114  CDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSY  173
            C +   C+N  G    C C  G+    D     C DI+EC+++   C  + +C NL G++
Sbjct  654  CSQL--CLNQPGG-FACACETGFELTPD--GFGCADIDECSQDYGNC--SDICINLLGTH  706

Query  174  KCECSAGFEPDSSGSGCVTEDFC-GTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVN  232
             C C  G+E       C+  D C G     C      C    G+F+C C  G+       
Sbjct  707  ACACERGYELAKDKLSCLDVDECAGLLSGGCS---HECINKAGTFECGCPLGYILNDDGR  763

Query  233  TCEP  236
            +C P
Sbjct  764  SCSP  767


 Score = 53.9 bits (128),  Expect = 4e-07, Method: Compositional matrix adjust.
 Identities = 71/247 (28%), Positives = 100/247 (40%), Gaps = 53/247 (21%)

Query  23   DHCSRVEH--AESCQSGDG-FWCACQKGFTPQGINL--SSTCIDIDECAQGLDNCKQ---  74
            D C+   H  + +CQ+  G + C C     P+G+NL    TC+  + C    + C+Q   
Sbjct  415  DECAEDTHLCSHTCQNTPGGYQCQC-----PEGLNLVEEYTCLAENLCEVNNNGCEQICL  469

Query  75   --KGGDCVNIPGSFTCGCGPYRQEKDG-VCIDINECSTNRGNCDENSDCINLDGEEQLCK  131
              +GG C    G        +R   DG  C D++EC  N G C +   C NL G    C 
Sbjct  470  TARGGVCACREG--------FRLSADGKSCEDVDECLVNNGGCQQV--CRNLPGSYG-CI  518

Query  132  CHKGW-TGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAG----------  180
            C  G+     D     C DI+EC++    C    +C NL GSY C C  G          
Sbjct  519  CAAGYELLKLDGIRGYCFDIDECSQRTHGCSDQMLCENLNGSYTCLCPPGYALGLDNHIV  578

Query  181  ------FEPDSSGS------GCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGA  228
                  F  DS+ S       C+  D C     +C      C   PG F+C C  G+  +
Sbjct  579  TSLNSSFITDSTSSETPSAHTCLDIDECSLANGNCSHF---CQNEPGGFQCACPLGYALS  635

Query  229  GTVNTCE  235
              + TC+
Sbjct  636  EDMRTCQ  642


 Score = 48.5 bits (114),  Expect = 2e-05, Method: Compositional matrix adjust.
 Identities = 63/229 (27%), Positives = 101/229 (44%), Gaps = 27/229 (11%)

Query  18   DAGGYDH-CSRVEHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECA--QGLDNCKQ  74
            D GG  H C R+ + +  Q  +   C C++G+T    N  ++C+DI+ECA  +   NC+ 
Sbjct  153  DNGGCAHICKRLLYPDENQPINK--CDCREGYT-LDPNDYASCLDINECANPELSSNCQ-  208

Query  75   KGGDCVNIPGSFTCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCK-CH  133
              G C N+PGS+ C   P  +       +I E   N      N   +N+   +   K C+
Sbjct  209  --GACENLPGSYRC-VEPLEENP-----EITEVVENPIE-KTNEVPVNVSESQPAGKTCN  259

Query  134  KGWTGNNDKPNVACRDINECN-ENPSICPSNSVCT----NLAGSYKCECSAGFEPDSSGS  188
             G+  + D     C+DINEC  + P    +N+VC     N  GS++C C  G+       
Sbjct  260  SGFQLSAD--GTDCQDINECEVDGPEDLDNNAVCQQKCENTIGSFRCTCVEGYHLLEDQR  317

Query  189  GCVTE---DFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAGTVNTC  234
             C  +   D      N          L  GS++C C +G+  +   ++C
Sbjct  318  SCALDSCTDLENPQLNRTRCAHECQDLPEGSYRCVCPKGYELSEDQHSC  366


> CE24549
Length=1664

 Score = 68.2 bits (165),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 60/192 (31%), Positives = 90/192 (46%), Gaps = 19/192 (9%)

Query  52   GINLS---STCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKDGVCID--IN  105
            G +LS    +C+DIDECA+  + C+     C N+ G++ C C   Y+  +DG   +  + 
Sbjct  282  GFHLSYDRRSCVDIDECAKN-NGCEHF---CENVKGTYRCKCREGYQLGRDGRTCEEMLG  337

Query  106  ECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSV  165
             C    G C    DC +      +CKC  G+   ND+    C DINEC+EN   C  + +
Sbjct  338  GCQVGNGGCQH--DCYDQPDGGHVCKCRNGYILANDQK--LCHDINECHENNGDC--SQI  391

Query  166  CTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGF  225
            C NLAGS +C+C  GF        C     C +    C+ +   CS   G + C C  GF
Sbjct  392  CVNLAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQI---CSNQEGGYMCSCEPGF  448

Query  226  RGAGTVNTCEPL  237
              +   ++C  +
Sbjct  449  ELSEDGHSCHDM  460


 Score = 40.8 bits (94),  Expect = 0.004, Method: Compositional matrix adjust.
 Identities = 33/95 (34%), Positives = 41/95 (43%), Gaps = 10/95 (10%)

Query  127  EQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSS  186
            EQ+C+C  G+TG   +      D NEC  N   C     C N  G+Y C C  GFE    
Sbjct  99   EQVCECPVGFTGAKCQ-----YDANECMANNGGCEHE--CVNTIGTYYCRCWPGFELSGD  151

Query  187  GSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCEC  221
            G+ C   D C      C      C   PG F+C+C
Sbjct  152  GNTCSDIDECAVSNGGCSD---RCVNSPGGFRCDC  183


 Score = 35.4 bits (80),  Expect = 0.19, Method: Compositional matrix adjust.
 Identities = 46/189 (24%), Positives = 74/189 (39%), Gaps = 21/189 (11%)

Query  50   PQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKDG-VCIDINEC  107
            P G   +    D +EC      C+    +CVN  G++ C C P +    DG  C DI+EC
Sbjct  105  PVGFTGAKCQYDANECMANNGGCEH---ECVNTIGTYYCRCWPGFELSGDGNTCSDIDEC  161

Query  108  STNRGNCDENSDCINLDGEEQLCKCHKGW----------TGNNDKPNVACRDINECNENP  157
            + + G C +   C+N  G  + C C              +G + +  +  + +  C+ + 
Sbjct  162  AVSNGGCSDR--CVNSPGGFR-CDCPSDLYLHADGRTCGSGFHFENLILIKKVTSCSTDN  218

Query  158  SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSF  217
              C       +    Y+C C  GF+   +   C   D C   K  C      C+   G  
Sbjct  219  GGCEHECENDSNGEFYRCRCRVGFKLSENKRSCQPVDPCFDNKGGCQ---HHCTNNHGRA  275

Query  218  KCECIQGFR  226
            +C+C  GF 
Sbjct  276  QCQCYPGFH  284


 Score = 32.3 bits (72),  Expect = 1.6, Method: Compositional matrix adjust.
 Identities = 41/147 (27%), Positives = 63/147 (42%), Gaps = 18/147 (12%)

Query  102  IDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICP  161
             D NEC  N G C+   +C+N  G    C+C  G+  + D     C DI+EC  +   C 
Sbjct  115  YDANECMANNGGCEH--ECVNTIGT-YYCRCWPGFELSGD--GNTCSDIDECAVSNGGC-  168

Query  162  SNSVCTNLAGSYKCECSAGF----EPDSSGSGCVTEDFCGTGK-NDCDTVFAACSL----  212
             +  C N  G ++C+C +      +  + GSG   E+     K   C T    C      
Sbjct  169  -SDRCVNSPGGFRCDCPSDLYLHADGRTCGSGFHFENLILIKKVTSCSTDNGGCEHECEN  227

Query  213  -VPGSF-KCECIQGFRGAGTVNTCEPL  237
               G F +C C  GF+ +    +C+P+
Sbjct  228  DSNGEFYRCRCRVGFKLSENKRSCQPV  254


> Hs20556510
Length=1007

 Score = 63.2 bits (152),  Expect = 7e-10, Method: Compositional matrix adjust.
 Identities = 55/177 (31%), Positives = 73/177 (41%), Gaps = 9/177 (5%)

Query  51   QGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDGVCIDINECSTN  110
            +    S    D+DEC +G DNC      C N P S+ C C          C D++EC   
Sbjct  19   RAAQYSKAAQDVDECVEGTDNC-HIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECE-R  76

Query  111  RGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLA  170
              N     DC+N+ G  + C C+ G+   +D  N  C D++EC E    C     C N+ 
Sbjct  77   EDNAGCVHDCVNIPGNYR-CTCYDGFHLAHDGHN--CLDVDECAEGNGGC--QQSCVNMM  131

Query  171  GSYKCECSAGFEPDSSGSGCVTEDFCGTG-KNDCDTVFAACSLVP-GSFKCECIQGF  225
            GSY+C C  GF    +   C+     G    N        C   P G   CEC  GF
Sbjct  132  GSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGF  188


 Score = 58.2 bits (139),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 42/137 (30%), Positives = 66/137 (48%), Gaps = 11/137 (8%)

Query  103  DINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINEC-NENPSICP  161
            D++EC     NC  ++ C N     + C C  G+TG+       C+D++EC  E+ + C 
Sbjct  29   DVDECVEGTDNCHIDAICQNTPRSYK-CICKSGYTGDGKH----CKDVDECEREDNAGCV  83

Query  162  SNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCEC  221
             +  C N+ G+Y+C C  GF     G  C+  D C  G   C     +C  + GS++C C
Sbjct  84   HD--CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQ---QSCVNMMGSYECHC  138

Query  222  IQGFRGAGTVNTCEPLP  238
             +GF  +   +TC   P
Sbjct  139  REGFFLSDNQHTCIQRP  155


 Score = 48.1 bits (113),  Expect = 2e-05, Method: Compositional matrix adjust.
 Identities = 44/138 (31%), Positives = 63/138 (45%), Gaps = 12/138 (8%)

Query  87   TCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVA  146
            TC  G   Q     C DI+EC  N G CD    C N  G  + C C KG+    ++ N  
Sbjct  268  TCPVGFMLQPDRKTCKDIDECRLNNGGCDH--ICRNTVGSFE-CSCKKGYKLLINERN--  322

Query  147  CRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTV  206
            C+DI+EC+ + +    + +C N  GS++C C  G+      + C   D C   +  C   
Sbjct  323  CQDIDECSFDRTC---DHICVNTPGSFQCLCHRGYLLYGI-THCGDVDECSINRGGCR--  376

Query  207  FAACSLVPGSFKCECIQG  224
               C   PGS++C C  G
Sbjct  377  -FGCINTPGSYQCTCPAG  393


 Score = 47.8 bits (112),  Expect = 4e-05, Method: Compositional matrix adjust.
 Identities = 40/129 (31%), Positives = 59/129 (45%), Gaps = 11/129 (8%)

Query  104  INECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSN  163
            I  C+ N G CD  S C +       C C  G+    D+    C+DI+EC  N   C  +
Sbjct  244  IETCAVNNGGCD--SKCHDA-ATGVHCTCPVGFMLQPDRK--TCKDIDECRLNNGGC--D  296

Query  164  SVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQ  223
             +C N  GS++C C  G++   +   C   D C   +  CD +   C   PGSF+C C +
Sbjct  297  HICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRT-CDHI---CVNTPGSFQCLCHR  352

Query  224  GFRGAGTVN  232
            G+   G  +
Sbjct  353  GYLLYGITH  361


 Score = 45.1 bits (105),  Expect = 2e-04, Method: Compositional matrix adjust.
 Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 4/89 (4%)

Query  146  ACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDT  205
            A +D++EC E    C  +++C N   SYKC C +G+  D  G  C   D C   + D   
Sbjct  26   AAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGD--GKHCKDVDEC--EREDNAG  81

Query  206  VFAACSLVPGSFKCECIQGFRGAGTVNTC  234
                C  +PG+++C C  GF  A   + C
Sbjct  82   CVHDCVNIPGNYRCTCYDGFHLAHDGHNC  110


 Score = 43.5 bits (101),  Expect = 6e-04, Method: Compositional matrix adjust.
 Identities = 53/207 (25%), Positives = 79/207 (38%), Gaps = 23/207 (11%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC--GPYRQEK  97
            + C C  GF     +    C+D+DECA+G   C+Q    CVN+ GS+ C C  G +  + 
Sbjct  93   YRCTCYDGF--HLAHDGHNCLDVDECAEGNGGCQQ---SCVNMMGSYECHCREGFFLSDN  147

Query  98   DGVCIDINECSTNRGNCDENSDCINLDGEEQ----LCKCHKGWTGNNDKPNVACRDIN--  151
               CI   E   N  N  +N  C ++  E       C+C  G+    ++ +  C  I   
Sbjct  148  QHTCIQRPEEGMNCMN--KNHGCAHICRETPKGGIACECRPGFELTKNQRDCKCEIIGMA  205

Query  152  -ECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAAC  210
              CN     C     C +     +C C   F   + G  C+  + C      CD+    C
Sbjct  206  VTCNYGNGGC--QHTCDDTEQGPRCGCHIKFVLHTDGKTCI--ETCAVNNGGCDS---KC  258

Query  211  SLVPGSFKCECIQGFRGAGTVNTCEPL  237
                    C C  GF       TC+ +
Sbjct  259  HDAATGVHCTCPVGFMLQPDRKTCKDI  285


>
Length=2634

 Score = 62.4 bits (150),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 63/200 (31%), Positives = 95/200 (47%), Gaps = 36/200 (18%)

Query  43   ACQKGFTPQGINLSSTCIDID-----ECAQGLDNCKQK----GGDCVNIPGSFTCGCGPY  93
             CQ G T    + S +CI ++     +C+   D+CKQ     G  C++  GSF C C   
Sbjct  342  VCQNGATCTNTHGSYSCICVNGWAGLDCSNNTDDCKQAACFYGATCIDGVGSFYCQC---  398

Query  94   RQEKDGVCIDINE-CSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVAC-RDIN  151
             + K G+   +++ C++N  + D   D   ++G    C C  G+ G      V C  DI+
Sbjct  399  TKGKTGLLCHLDDACTSNPCHADAICDTSPINGS-YACSCATGYKG------VDCSEDID  451

Query  152  ECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTV----F  207
            EC++  S C  N +C N  GSY+C CS GF          T   C T  N+C++      
Sbjct  452  ECDQG-SPCEHNGICVNTPGSYRCNCSQGF----------TGPRCETNINECESHPCQNE  500

Query  208  AACSLVPGSFKCECIQGFRG  227
             +C   PG+F+C C+ GF G
Sbjct  501  GSCLDDPGTFRCVCMPGFTG  520


 Score = 52.4 bits (124),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 60/199 (30%), Positives = 91/199 (45%), Gaps = 40/199 (20%)

Query  61   DIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDGVCID---INECSTNRGNCDE-  116
            D+DECAQ      Q G  C N  GS++C           +C++     +CS N  +C + 
Sbjct  331  DVDECAQRDHPVCQNGATCTNTHGSYSC-----------ICVNGWAGLDCSNNTDDCKQA  379

Query  117  ----NSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVC--TNLA  170
                 + CI+  G    C+C KG TG      + C   + C  NP  C ++++C  + + 
Sbjct  380  ACFYGATCIDGVGSF-YCQCTKGKTG------LLCHLDDACTSNP--CHADAICDTSPIN  430

Query  171  GSYKCECSAGFEPDSSGSGCVTE-DFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAG  229
            GSY C C+ G++    G  C  + D C  G + C+     C   PGS++C C QGF G  
Sbjct  431  GSYACSCATGYK----GVDCSEDIDECDQG-SPCEH-NGICVNTPGSYRCNCSQGFTGPR  484

Query  230  ---TVNTCEPLPGNEDLAC  245
                +N CE  P   + +C
Sbjct  485  CETNINECESHPCQNEGSC  503


 Score = 50.1 bits (118),  Expect = 7e-06, Method: Compositional matrix adjust.
 Identities = 58/190 (30%), Positives = 78/190 (41%), Gaps = 27/190 (14%)

Query  40    FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDG  99
             + C C++GF  Q   L     +ID+CA    N  Q GG C +   +F+C C P      G
Sbjct  1205  YECQCRQGFQGQNCEL-----NIDDCAP---NPCQNGGTCHDRVMNFSCSCPPGTM---G  1253

Query  100   VCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACR-DINECNENPS  158
             +  +IN+     G C  N  CI+  G  + C C  G+ G        C  DINEC  NP 
Sbjct  1254  IICEINKDDCKPGACHNNGSCIDRVGGFE-CVCQPGFVG------ARCEGDINECLSNPC  1306

Query  159   ICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTE-DFCGTGKNDCDTVFAACSLVPGSF  217
                    C  L  +Y C C     P   G  C  + DFC   ++ C      C++     
Sbjct  1307  SNAGTLDCVQLVNNYHCNC----RPGHMGRHCEHKVDFC--AQSPCQN-GGNCNIRQSGH  1359

Query  218   KCECIQGFRG  227
              C C  GF G
Sbjct  1360  HCICNNGFYG  1369


 Score = 47.0 bits (110),  Expect = 5e-05, Method: Compositional matrix adjust.
 Identities = 60/198 (30%), Positives = 86/198 (43%), Gaps = 42/198 (21%)

Query  39   GFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP----YR  94
            G+ C C  G+T      +S  I+I++C    D+     G C++   SF C C P    Y 
Sbjct  585  GYSCECPPGYTG-----TSCEININDC----DSNPCHRGKCIDDVNSFKCLCDPGYTGYI  635

Query  95   QEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECN  154
             +K      INEC +N   C  +  C +  G    C+C  G +G N + NV     NEC+
Sbjct  636  CQKQ-----INECESNP--CQFDGHCQDRVGS-YYCQCQAGTSGKNCEVNV-----NECH  682

Query  155  ENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAA----C  210
             NP  C + + C +   SYKC+C  GF          T   C    ++C +   A    C
Sbjct  683  SNP--CNNGATCIDGINSYKCQCVPGF----------TGQHCEKNVDECISSPCANNGVC  730

Query  211  SLVPGSFKCECIQGFRGA  228
                  +KCEC +GF  A
Sbjct  731  IDQVNGYKCECPRGFYDA  748


 Score = 44.3 bits (103),  Expect = 4e-04, Method: Compositional matrix adjust.
 Identities = 62/223 (27%), Positives = 91/223 (40%), Gaps = 53/223 (23%)

Query  38   DGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEK  97
            + F C C  G+T            I+EC     N  Q  G C +  GS+ C C      K
Sbjct  621  NSFKCLCDPGYTGYICQKQ-----INECES---NPCQFDGHCQDRVGSYYCQCQAGTSGK  672

Query  98   DGVCIDINECSTNRGNCDENSDCINLDG-EEQLCKCHKGWTGNNDKPNVACRDINECNEN  156
            +   +++NEC +N   C+  + CI  DG     C+C  G+TG + + NV     +EC  +
Sbjct  673  NCE-VNVNECHSNP--CNNGATCI--DGINSYKCQCVPGFTGQHCEKNV-----DECISS  722

Query  157  PSICPSNSVCTNLAGSYKCECSAGFE--------PDSSGSGCVTEDFCGTGKND------  202
            P  C +N VC +    YKCEC  GF          + + + CV E  C  G N+      
Sbjct  723  P--CANNGVCIDQVNGYKCECPRGFYDAHCLSDVDECASNPCVNEGRCEDGINEFICHCP  780

Query  203  -------CDTVFAACSLVP-----------GSFKCECIQGFRG  227
                   C+     CS  P            +F C+C+ G+ G
Sbjct  781  PGYTGKRCELDIDECSSNPCQHGGTCYDKLNAFSCQCMPGYTG  823


 Score = 43.1 bits (100),  Expect = 8e-04, Method: Compositional matrix adjust.
 Identities = 61/233 (26%), Positives = 90/233 (38%), Gaps = 74/233 (31%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEK-  97
            F C C  G+T +   L     DIDEC+    N  Q GG C +   +F+C C P Y  +K 
Sbjct  775  FICHCPPGYTGKRCEL-----DIDECSS---NPCQHGGTCYDKLNAFSCQCMPGYTGQKC  826

Query  98   --------------DGVCID---------------------INECSTNR----GNCDENS  118
                           G CID                     ++ C++NR      C  +S
Sbjct  827  ETNIDDCVTNPCGNGGTCIDKVNGYKCVCKVPFTGRDCESKMDPCASNRCKNEAKCTPSS  886

Query  119  DCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECS  178
            + ++       C C  G+TG          DI+EC+ + S C + + C N+ GSY+C C+
Sbjct  887  NFLDFS-----CTCKLGYTGR-----YCDEDIDECSLS-SPCRNGASCLNVPGSYRCLCT  935

Query  179  AGFEPDSSGSGCVTEDFCGTGKNDCDTV----FAACSLVPGSFKCECIQGFRG  227
             G+E             C    +DC +        C    G + C C+ GF G
Sbjct  936  KGYEGRD----------CAINTDDCASFPCQNGGTCLDGIGDYSCLCVDGFDG  978


 Score = 42.0 bits (97),  Expect = 0.002, Method: Compositional matrix adjust.
 Identities = 45/146 (30%), Positives = 61/146 (41%), Gaps = 24/146 (16%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGS--FTCGCGPYRQEK  97
            + CAC  G+T +     + C            C+  G  C  + GS  FTC C P     
Sbjct  162  YTCACANGYTGERCETKNLCAS--------SPCR-NGATCTALAGSSSFTCSCPPGF-TG  211

Query  98   DGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNN-DKPNVACRDINECNEN  156
            D    DI EC +N   C     C+N  G  Q C C  G+TG + D     C        +
Sbjct  212  DTCSYDIEECQSNP--CKYGGTCVNTHGSYQ-CMCPTGYTGKDCDTKYKPC--------S  260

Query  157  PSICPSNSVCTNLAGSYKCECSAGFE  182
            PS C +  +C +   SY+C+C  GFE
Sbjct  261  PSPCQNGGICRSNGLSYECKCPKGFE  286


 Score = 36.6 bits (83),  Expect = 0.074, Method: Compositional matrix adjust.
 Identities = 67/227 (29%), Positives = 91/227 (40%), Gaps = 66/227 (29%)

Query  40   FWCACQKGFTPQGINLSSTC-IDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKD  98
            F C C  GFT       + C IDIDEC     N     G C +    F C C        
Sbjct  510  FRCVCMPGFT------GTQCEIDIDECQS---NPCLNDGTCHDKINGFKCSCA--LGFTG  558

Query  99   GVC-IDINECST----NRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNV--------  145
              C I+I++C +    NRG C ++     + G    C+C  G+TG + + N+        
Sbjct  559  ARCQINIDDCQSQPCRNRGICHDS-----IAGYS--CECPPGYTGTSCEININDCDSNPC  611

Query  146  ---ACRD---------------------INECNENPSICPSNSVCTNLAGSYKCECSAGF  181
                C D                     INEC  NP  C  +  C +  GSY C+C AG 
Sbjct  612  HRGKCIDDVNSFKCLCDPGYTGYICQKQINECESNP--CQFDGHCQDRVGSYYCQCQAG-  668

Query  182  EPDSSGSGC-VTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRG  227
               +SG  C V  + C +  N C+   A C     S+KC+C+ GF G
Sbjct  669  ---TSGKNCEVNVNECHS--NPCNN-GATCIDGINSYKCQCVPGFTG  709


> Hs4557799
Length=2321

 Score = 62.4 bits (150),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 59/199 (29%), Positives = 86/199 (43%), Gaps = 42/199 (21%)

Query  39   GFWCACQKGFTPQGINLSSTCIDIDECAQGL--DNCKQK----GGDCVNIPGSFTCGCGP  92
            GF C C+ G++               C+Q L  D C+ +    GG C +    F C C P
Sbjct  715  GFRCVCEPGWS------------GPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPP  762

Query  93   YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINE  152
              Q +   C  ++ C+ N   C+    C +  G+  +C C +GW G   +     +D++E
Sbjct  763  GVQGRQ--CELLSPCTPN--PCEHGGRCESAPGQLPVCSCPQGWQGPRCQ-----QDVDE  813

Query  153  CNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVF----A  208
            C   P+ C  + +CTNLAGS+ C C  G+          T   C    NDCD        
Sbjct  814  C-AGPAPCGPHGICTNLAGSFSCTCHGGY----------TGPSCDQDINDCDPNPCLNGG  862

Query  209  ACSLVPGSFKCECIQGFRG  227
            +C    GSF C C+ GF G
Sbjct  863  SCQDGVGSFSCSCLPGFAG  881


 Score = 49.7 bits (117),  Expect = 9e-06, Method: Compositional matrix adjust.
 Identities = 76/261 (29%), Positives = 99/261 (37%), Gaps = 65/261 (24%)

Query  30   HAESCQSG-DG-FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFT  87
            H   C  G DG F C+C  G+  QG +  S   D+DEC  G + C+  GG C+N PGSF 
Sbjct  130  HGARCSVGPDGRFLCSCPPGY--QGRSCRS---DVDECRVG-EPCRH-GGTCLNTPGSFR  182

Query  88   C----------------GCGPYRQEKDGVCID----INECSTNRG----NCDENSD----  119
            C                 C P      G C        +C+   G    NC+ N D    
Sbjct  183  CQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPG  242

Query  120  --CIN----LDGEEQL-CKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGS  172
              C+N    +DG     C+C   WTG          D++EC   P+ C +   C N  G 
Sbjct  243  HRCLNGGTCVDGVNTYNCQCPPEWTGQ-----FCTEDVDECQLQPNACHNGGTCFNTLGG  297

Query  173  YKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVF----AACSLVPGSFKCECIQGFRGA  228
            + C C  G+          T + C    +DC T      A C     SF C C  G  G 
Sbjct  298  HSCVCVNGW----------TGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGL  347

Query  229  --GTVNTCEPLPGNEDLACTT  247
                 + C   P +ED  C T
Sbjct  348  LCHLDDACVSNPCHEDAICDT  368


 Score = 44.3 bits (103),  Expect = 4e-04, Method: Compositional matrix adjust.
 Identities = 61/223 (27%), Positives = 84/223 (37%), Gaps = 60/223 (26%)

Query  42   CACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKDGVC  101
            C C  GFT    +      D+DEC+ G + C+  G  CVN  GSF C CG  R      C
Sbjct  377  CTCPPGFTGGACDQ-----DVDECSIGANPCEHLG-RCVNTQGSFLCQCG--RGYTGPRC  428

Query  102  -IDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGN--------------------N  140
              D+NEC +  G C   + C++  G+   C C  G+TG                      
Sbjct  429  ETDVNECLS--GPCRNQATCLDRIGQF-TCICMAGFTGTYCEVDIDECQSSPCVNGGVCK  485

Query  141  DKPN-VACR------------DINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSG  187
            D+ N  +C             D++EC   P  C + + C +    Y+C C+ GFE     
Sbjct  486  DRVNGFSCTCPSGFSGSTCQLDVDECASTP--CRNGAKCVDQPDGYECRCAEGFE-----  538

Query  188  SGCVTEDFCGTGKNDCDT---VFAACSLVPGSFKCECIQGFRG  227
                    C    +DC         C     SF C C  G+ G
Sbjct  539  -----GTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTG  576


 Score = 43.1 bits (100),  Expect = 0.001, Method: Compositional matrix adjust.
 Identities = 51/175 (29%), Positives = 76/175 (43%), Gaps = 30/175 (17%)

Query  63   DECAQGLDNCKQ----KGGDCVNIPGSFTCGCGPYRQEKDGVCIDINE-CSTNRGNCDEN  117
            + C+Q +D+C       G  C +   SF C C      K G+   +++ C +N   C E+
Sbjct  309  ESCSQNIDDCATAVCFHGATCHDRVASFYCAC---PMGKTGLLCHLDDACVSN--PCHED  363

Query  118  SDC-INLDGEEQLCKCHKGWTGNNDKPNVAC-RDINECNENPSICPSNSVCTNLAGSYKC  175
            + C  N      +C C  G+TG       AC +D++EC+   + C     C N  GS+ C
Sbjct  364  AICDTNPVNGRAICTCPPGFTGG------ACDQDVDECSIGANPCEHLGRCVNTQGSFLC  417

Query  176  ECSAGFEPDSSGSGC---VTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRG  227
            +C  G+    +G  C   V E   G  +N      A C    G F C C+ GF G
Sbjct  418  QCGRGY----TGPRCETDVNECLSGPCRNQ-----ATCLDRIGQFTCICMAGFTG  463


 Score = 40.8 bits (94),  Expect = 0.004, Method: Compositional matrix adjust.
 Identities = 51/174 (29%), Positives = 75/174 (43%), Gaps = 41/174 (23%)

Query  13   SSTPCDAGGYDHCSRVEHAESCQSGDGFWCACQKGFTPQGINLSSTC-IDIDECAQGLDN  71
            +STPC  G          A+     DG+ C C +GF        + C  ++D+C+   D 
Sbjct  512  ASTPCRNG----------AKCVDQPDGYECRCAEGFE------GTLCDRNVDDCSP--DP  553

Query  72   CKQKGGDCVNIPGSFTCGCGP----YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEE  127
            C    G CV+   SF+C C P     R E       ++EC +    C     C++L  ++
Sbjct  554  CHH--GRCVDGIASFSCACAPGYTGTRCESQ-----VDECRSQ--PCRHGGKCLDLV-DK  603

Query  128  QLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGF  181
             LC+C  G TG N + N     I++C  NP    +  VC +    Y C C  GF
Sbjct  604  YLCRCPSGTTGVNCEVN-----IDDCASNPC---TFGVCRDGINRYDCVCQPGF  649


 Score = 35.0 bits (79),  Expect = 0.26, Method: Compositional matrix adjust.
 Identities = 34/108 (31%), Positives = 47/108 (43%), Gaps = 20/108 (18%)

Query  40    FWCACQKGFTPQGINLSSTC-IDIDECAQG--LDNCKQ--KGGDCVNIPGSFTCGCGP--  92
             + C+C  G       L   C I+ D+C  G  LD+  +    G CV++ G F C C P  
Sbjct  1144  YLCSCPPG------TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGY  1197

Query  93    --YRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTG  138
                R E D     INEC +   +     DC+   G    C CH G++G
Sbjct  1198  TGLRCEAD-----INECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSG  1240


 Score = 34.3 bits (77),  Expect = 0.42, Method: Compositional matrix adjust.
 Identities = 36/120 (30%), Positives = 46/120 (38%), Gaps = 22/120 (18%)

Query  114  CDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTN--LAG  171
            C     C  L   E  C C  GW G        C+  + C+  P  C    VC +  +AG
Sbjct  49   CANGGRCTQLPSREAACLCPPGWVGER------CQLEDPCHSGP--CAGRGVCQSSVVAG  100

Query  172  S--YKCECSAGFE-PDSSGSGCVTEDFCGTGKNDCDTVFAACSLVP-GSFKCECIQGFRG  227
            +  + C C  GF  PD S         C  G        A CS+ P G F C C  G++G
Sbjct  101  TARFSCRCPRGFRGPDCSLPDPCLSSPCAHG--------ARCSVGPDGRFLCSCPPGYQG  152


 Score = 33.9 bits (76),  Expect = 0.47, Method: Compositional matrix adjust.
 Identities = 66/240 (27%), Positives = 86/240 (35%), Gaps = 67/240 (27%)

Query  29   EHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTC  88
            EH   C+S  G    C     PQG        D+DECA G   C   G  C N+ GSF+C
Sbjct  781  EHGGRCESAPGQLPVCS---CPQGWQGPRCQQDVDECA-GPAPCGPHG-ICTNLAGSFSC  835

Query  89   GC-----GPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKP  143
             C     GP   +      DIN+C  N   C     C +  G    C C  G+ G    P
Sbjct  836  TCHGGYTGPSCDQ------DINDCDPN--PCLNGGSCQDGVGSFS-CSCLPGFAG----P  882

Query  144  NVACRDINECNENP-----------------------------------SICPSNSVCTN  168
              A RD++EC  NP                                   S C +   C +
Sbjct  883  RCA-RDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVD  941

Query  169  LAGSYKCECSAGFEPDSSGSGCVTE-DFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRG  227
               S+ C C  G+    +G+ C  E D C +    C      CS     F+C C++ F G
Sbjct  942  GVNSFSCLCRPGY----TGAHCQHEADPCLS--RPC-LHGGVCSAAHPGFRCTCLESFTG  994


 Score = 31.2 bits (69),  Expect = 3.1, Method: Compositional matrix adjust.
 Identities = 42/153 (27%), Positives = 60/153 (39%), Gaps = 23/153 (15%)

Query  39    GFWCACQKGFT-PQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCG----PY  93
             GF C C + FT PQ   L   C     C  G   C Q G  C+  PG     C     P 
Sbjct  983   GFRCTCLESFTGPQCQTLVDWC-SRQPCQNG-GRCVQTGAYCLCPPGWSGRLCDIRSLPC  1040

Query  94    RQEKDGVCIDINECSTNRGNC-DENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINE  152
             R+    + + + +     G C DE+S           C C +G TG++ +     ++++ 
Sbjct  1041  REAAAQIGVRLEQLCQAGGQCVDEDS--------SHYCVCPEGRTGSHCE-----QEVDP  1087

Query  153   CNENPSICPSNSVCTNLAGSYKCECSAGFEPDS  185
             C   P  C     C    G Y CEC  G+  D+
Sbjct  1088  CLAQP--CQHGGTCRGYMGGYMCECLPGYNGDN  1118


> Hs13249344
Length=2471

 Score = 61.2 bits (147),  Expect = 3e-09, Method: Compositional matrix adjust.
 Identities = 61/202 (30%), Positives = 87/202 (43%), Gaps = 40/202 (19%)

Query  50   PQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC-----GPYRQEKDGVCIDI  104
            PQG   +    D+DECA    N  +  G CVN  G+F C C     GP  +      +DI
Sbjct  404  PQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE------MDI  457

Query  105  NECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACR-DINECNENPSICPSN  163
            NEC ++   C  ++ C++  G    C C  G+ G      V C  +INEC  NP  C +N
Sbjct  458  NECHSDP--CQNDATCLDKIGGF-TCLCMPGFKG------VHCELEINECQSNP--CVNN  506

Query  164  SVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVF----AACSLVPGSFKC  219
              C +    ++C C  GF          T   C    +DC +      A C   P  ++C
Sbjct  507  GQCVDKVNRFQCLCPPGF----------TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYEC  556

Query  220  ECIQGFRGA---GTVNTCEPLP  238
            +C  GF G      ++ C+P P
Sbjct  557  QCATGFTGVLCEENIDNCDPDP  578


 Score = 53.5 bits (127),  Expect = 7e-07, Method: Compositional matrix adjust.
 Identities = 61/196 (31%), Positives = 85/196 (43%), Gaps = 25/196 (12%)

Query  38    DGFWCACQKGFTPQGINLSSTCI-DIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQE  96
             + F C C  GFT       S C+ +I+EC+     C  +G  CV+  G++ C C P    
Sbjct  1007  NSFSCLCPVGFT------GSFCLHEINECSS--HPCLNEG-TCVDGLGTYRCSC-PLGYT  1056

Query  97    KDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNN-DKPNVACRDINECNE  155
                    +N CS  R  C     C+    E Q C C  GW G   D PNV+C DI     
Sbjct  1057  GKNCQTLVNLCS--RSPCKNKGTCVQKKAESQ-CLCPSGWAGAYCDVPNVSC-DIAASRR  1112

Query  156   N---PSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSL  212
                   +C  + VC N   ++ C+C  G+    +GS C  E       N C    A CS 
Sbjct  1113  GVLVEHLCQHSGVCINAGNTHYCQCPLGY----TGSYC-EEQLDECASNPCQH-GATCSD  1166

Query  213   VPGSFKCECIQGFRGA  228
               G ++CEC+ G++G 
Sbjct  1167  FIGGYRCECVPGYQGV  1182


 Score = 52.8 bits (125),  Expect = 1e-06, Method: Compositional matrix adjust.
 Identities = 62/214 (28%), Positives = 87/214 (40%), Gaps = 36/214 (16%)

Query  21   GYDHCSRVEHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCV  80
            GY+ C       +  +G G+ C C +GF      L   C   D C +   N  Q GG CV
Sbjct  31   GYEPCVNEGMCVTYHNGTGY-CKCPEGF------LGEYCQHRDPCEK---NRCQNGGTCV  80

Query  81   N--IPGSFTCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTG  138
               + G  TC C      +D      + C  +R  C     C  L  +   C C  G+TG
Sbjct  81   AQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRP-CLNGGTCHMLSRDTYECTCQVGFTG  139

Query  139  NNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGT  198
                    C+  + C  +P  C + S CT +A  + C+C  GF          T   C T
Sbjct  140  KE------CQWTDACLSHP--CANGSTCTTVANQFSCKCLTGF----------TGQKCET  181

Query  199  GKNDCDTV-----FAACSLVPGSFKCECIQGFRG  227
              N+CD          C  +PGS++C+C+QGF G
Sbjct  182  DVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTG  215


 Score = 49.7 bits (117),  Expect = 9e-06, Method: Compositional matrix adjust.
 Identities = 72/234 (30%), Positives = 95/234 (40%), Gaps = 35/234 (14%)

Query  38   DGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEK  97
            +G+ C C+KGF  +G N     ++IDECA    N     G C +    +TC C      K
Sbjct  777  NGYRCTCKKGF--KGYNCQ---VNIDECAS---NPCLNQGTCFDDISGYTCHCVLPYTGK  828

Query  98   DGVCIDINECSTNRGNCDENSDCI-NLDGEEQLCKCHKGWTGNNDKPNVACRDINECNEN  156
            +   + +  CS N   C+  + C  + + E   C C  GW G          DI+EC   
Sbjct  829  NCQTV-LAPCSPNP--CENAAVCKESPNFESYTCLCAPGWQGQR-----CTIDIDECISK  880

Query  157  PSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGS  216
            P  C ++ +C N  GSY CEC  GF    SG  C  ED      N C     +C     +
Sbjct  881  P--CMNHGLCHNTQGSYMCECPPGF----SGMDC-EEDIDDCLANPCQN-GGSCMDGVNT  932

Query  217  FKCECIQGFRG---AGTVNTCEPLPGNEDLACTTLGLTCGDYKYCTKSTTQAGL  267
            F C C+ GF G      +N C   P          G TC DY        QAG 
Sbjct  933  FSCLCLPGFTGDKCQTDMNECLSEPCKN-------GGTCSDYVNSYTCKCQAGF  979


 Score = 48.9 bits (115),  Expect = 2e-05, Method: Compositional matrix adjust.
 Identities = 58/198 (29%), Positives = 82/198 (41%), Gaps = 23/198 (11%)

Query  39    GFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEKD  98
             G+ C C  G+  QG+N      ++DEC    +   Q GG C+++   F C C P  +   
Sbjct  1170  GYRCECVPGY--QGVNCE---YEVDECQ---NQPCQNGGTCIDLVNHFKCSCPPGTR---  1218

Query  99    GVCIDINECSTNRG-NCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENP  157
             G+  + N     RG +C     C++  G    C+C  G+ G   +      DINEC  NP
Sbjct  1219  GLLCEENIDDCARGPHCLNGGQCMDRIGGYS-CRCLPGFAGERCE-----GDINECLSNP  1272

Query  158   SICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCVT-EDFCGTGKNDCDTVFAACSLVPGS  216
                  +  C  L   Y C C + F    +G  C T  D C           A  S +P  
Sbjct  1273  CSSEGSLDCIQLTNDYLCVCRSAF----TGRHCETFVDVCPQMPCLNGGTCAVASNMPDG  1328

Query  217   FKCECIQGFRGAGTVNTC  234
             F C C  GF GA   ++C
Sbjct  1329  FICRCPPGFSGARCQSSC  1346


 Score = 45.8 bits (107),  Expect = 1e-04, Method: Compositional matrix adjust.
 Identities = 68/231 (29%), Positives = 88/231 (38%), Gaps = 69/231 (29%)

Query  40   FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGC-----GPY-  93
            F C C  GFT Q         D++EC   +    Q GG C+N+PGS+ C C     G Y 
Sbjct  166  FSCKCLTGFTGQKCE-----TDVNEC--DIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYC  218

Query  94   ------------------RQEKDGV----CIDINECSTNRGNCDE--NSDCIN----LDG  125
                              RQ  D      C+   E ST   N D+  N  C N    +DG
Sbjct  219  DSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDG  278

Query  126  EEQL-CKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPD  184
                 C+C   WTG          D++EC   P+ C +   C N  G Y C C  G+   
Sbjct  279  VNTYNCRCPPQWTGQ-----FCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGW---  330

Query  185  SSGSGCVTEDFCGTGKNDCDTVFAACSLVPG--------SFKCECIQGFRG  227
                   + D C    +DC   FA+C+  PG        SF C C +G  G
Sbjct  331  -------SGDDCSENIDDC--AFASCT--PGSTCIDRVASFSCMCPEGKAG  370


 Score = 44.7 bits (104),  Expect = 3e-04, Method: Compositional matrix adjust.
 Identities = 63/211 (29%), Positives = 83/211 (39%), Gaps = 42/211 (19%)

Query  38    DGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGPYRQEK  97
             + + C C  G+  Q        IDIDEC   +       G C N  GS+ C C P     
Sbjct  855   ESYTCLCAPGWQGQRCT-----IDIDEC---ISKPCMNHGLCHNTQGSYMCECPPGFSGM  906

Query  98    DGVCIDINECSTNRGNCDENSDCINLDGEEQL-CKCHKGWTGNNDKPNVACRDINECNEN  156
             D    DI++C  N   C     C  +DG     C C  G+TG+  +      D+NEC   
Sbjct  907   DCE-EDIDDCLANP--CQNGGSC--MDGVNTFSCLCLPGFTGDKCQ-----TDMNECLSE  956

Query  157   PSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGC------VTEDFCGTGKNDCDTVFAAC  210
             P  C +   C++   SY C+C AGF+    G  C       TE  C  G    D +    
Sbjct  957   P--CKNGGTCSDYVNSYTCKCQAGFD----GVHCENNINECTESSCFNGGTCVDGI----  1006

Query  211   SLVPGSFKCECIQGFRGA---GTVNTCEPLP  238
                  SF C C  GF G+     +N C   P
Sbjct  1007  ----NSFSCLCPVGFTGSFCLHEINECSSHP  1033


 Score = 37.4 bits (85),  Expect = 0.040, Method: Compositional matrix adjust.
 Identities = 60/193 (31%), Positives = 94/193 (48%), Gaps = 33/193 (17%)

Query  38   DGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNIPGSFTCGCGP-YRQE  96
            +G+ C CQ G +  G+N     I+ D+CA   + C    G C++    ++C C P +  +
Sbjct  627  NGYQCNCQPGTS--GVNCE---INFDDCAS--NPCIH--GICMDGINRYSCVCSPGFTGQ  677

Query  97   KDGVCIDINECSTNRGNCDENSDCIN-LDGEEQLCKCHKGWTGNNDKPNVACRDINECNE  155
            +    IDI+EC++N   C + + CIN ++G    C C +G       P+     +NEC  
Sbjct  678  RCN--IDIDECASNP--CRKGATCINGVNGFR--CICPEG----PHHPSCY-SQVNECLS  726

Query  156  NPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGC-VTEDFCGTGKNDCDTVFAACSLVP  214
            NP I   +  CT     YKC C AG+     G  C V ++ C +  N C       +LV 
Sbjct  727  NPCI---HGNCTGGLSGYKCLCDAGW----VGINCEVDKNECLS--NPCQNGGTCDNLVN  777

Query  215  GSFKCECIQGFRG  227
            G ++C C +GF+G
Sbjct  778  G-YRCTCKKGFKG  789


 Score = 36.6 bits (83),  Expect = 0.072, Method: Compositional matrix adjust.
 Identities = 48/159 (30%), Positives = 69/159 (43%), Gaps = 35/159 (22%)

Query  30   HAESCQSG-DGFWCACQKGFTPQGINLSSTCID-IDECAQG--LDNCKQKGGDCVNIPGS  85
            H   CQ G D + C C  G+      + + C D IDEC     L++     G C+++   
Sbjct  580  HHGQCQDGIDSYTCICNPGY------MGAICSDQIDECYSSPCLND-----GRCIDLVNG  628

Query  86   FTCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCIN---LDGEEQL-CKCHKGWTGNND  141
            + C C P      GV      C  N  +C  N  CI+   +DG  +  C C  G+TG   
Sbjct  629  YQCNCQP---GTSGV-----NCEINFDDCASNP-CIHGICMDGINRYSCVCSPGFTGQ--  677

Query  142  KPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAG  180
            + N+   DI+EC  NP  C   + C N    ++C C  G
Sbjct  678  RCNI---DIDECASNP--CRKGATCINGVNGFRCICPEG  711


>
Length=3138

 Score = 61.2 bits (147),  Expect = 3e-09, Method: Compositional matrix adjust.
 Identities = 55/163 (33%), Positives = 77/163 (47%), Gaps = 17/163 (10%)

Query  29   EHAESCQSGD--GFWCACQKGFTPQGINLSST----CI-DIDECAQGLDNCKQKGGDCVN  81
            EH    Q+ +  G+ C C +G+T    N++S     C+ D+DEC   ++ C     +C+N
Sbjct  195  EHGTCIQAANSAGYVCICDQGWTWADANVTSASPSACVRDVDECEPRVNPCHD---ECIN  251

Query  82   IPGSFTCGCGPYRQEKDG-VCIDINEC-STNRGNC--DENSDCINLDGEEQLCKCHKGWT  137
            +PGSF CG  P     DG  C DI+EC S + G C       C N +G  +  +C  GWT
Sbjct  252  LPGSFRCGACPTGYTGDGRFCRDIDECASEDNGGCSLQPRVTCTNTEGSHRCGRCPAGWT  311

Query  138  GNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAG  180
            G  D       D N CN N  IC   + C  ++    C C  G
Sbjct  312  G--DGRTCTASDSNSCN-NEGICHPLAKCEYVSDMVVCTCPLG  351


 Score = 52.0 bits (123),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 71/241 (29%), Positives = 97/241 (40%), Gaps = 55/241 (22%)

Query  14   STPCDAGGYDHCSRVEHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDEC----AQGL  69
            S PC  GG  H           +  GF C C     P G    S   D++EC       L
Sbjct  104  SNPCKNGGTCH----------DAYKGFQCEC-----PAGWQGDSCEDDVNECFTLAGTDL  148

Query  70   DNCKQKGGDCVNIPGSFTCGC-----GPYRQEKDGVCIDINECSTNRGNCDENSDCIN-L  123
            D C    G C+N PGS+ C C     G + + +   C+       +R  C E+  CI   
Sbjct  149  DGCL-NNGQCINTPGSYRCVCRNGFTGTHCRLRHNTCL----FGGSRELCGEHGTCIQAA  203

Query  124  DGEEQLCKCHKGWT-----GNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKC-EC  177
            +    +C C +GWT       +  P+   RD++EC   P + P +  C NL GS++C  C
Sbjct  204  NSAGYVCICDQGWTWADANVTSASPSACVRDVDEC--EPRVNPCHDECINLPGSFRCGAC  261

Query  178  SAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVP--------GSFKC-ECIQGFRGA  228
              G+  D  G  C   D C +  N        CSL P        GS +C  C  G+ G 
Sbjct  262  PTGYTGD--GRFCRDIDECASEDN------GGCSLQPRVTCTNTEGSHRCGRCPAGWTGD  313

Query  229  G  229
            G
Sbjct  314  G  314


> Hs6679056
Length=1376

 Score = 60.8 bits (146),  Expect = 4e-09, Method: Compositional matrix adjust.
 Identities = 55/184 (29%), Positives = 77/184 (41%), Gaps = 28/184 (15%)

Query  22   YDHCSRVEHAESCQSGDG--FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDC  79
            YD     +    C  G G  + C C  G+   G N    C+D +ECA G   C      C
Sbjct  765  YDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRN----CVDENECATGFHRCG-PNSVC  819

Query  80   VNIPGSFTCGC--GPYRQEKDGVCIDI----NECSTNRGNCDE--NSDCINLDGEEQLCK  131
            +N+PGS+ C C  G    +    CI I    N C      C     + C++  G    C 
Sbjct  820  INLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCA  879

Query  132  CHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFE-------PD  184
            C  G+ G+  +    C D++EC+EN   C   + C N  GS+ C C  G+        PD
Sbjct  880  CLPGYAGDGHQ----CTDVDECSEN--RCHPAATCYNTPGSFSCRCQPGYYGDGFQCIPD  933

Query  185  SSGS  188
            S+ S
Sbjct  934  STSS  937


 Score = 58.9 bits (141),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 46/151 (30%), Positives = 66/151 (43%), Gaps = 12/151 (7%)

Query  85   SFTCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPN  144
            + T   GP +++ D     +N C      CD  + C    G +  C+C  G+ G+     
Sbjct  744  AVTNQIGPVKEDSDPT--PVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRN--  799

Query  145  VACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCV----TEDFCGTGK  200
              C D NEC      C  NSVC NL GSY+CEC +G+E       C+      + C  G 
Sbjct  800  --CVDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGS  857

Query  201  NDCDTVFAACSLVPG--SFKCECIQGFRGAG  229
            + C     A  +  G  +F C C+ G+ G G
Sbjct  858  HTCAPAGQARCVHHGGSTFSCACLPGYAGDG  888


 Score = 56.6 bits (135),  Expect = 7e-08, Method: Compositional matrix adjust.
 Identities = 49/149 (32%), Positives = 65/149 (43%), Gaps = 11/149 (7%)

Query  86   FTCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPN-  144
            +TC C    Q     C+D NEC+T    C  NS CINL G  + C+C  G+   +D+   
Sbjct  785  YTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYR-CECRSGYEFADDRHTC  843

Query  145  -VACRDINECNENPSICPS--NSVCTNLAGS-YKCECSAGFEPDSSGSGCVTEDFCGTGK  200
             +     N C +    C     + C +  GS + C C  G+  D  G  C   D C   +
Sbjct  844  ILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGD--GHQCTDVDEC--SE  899

Query  201  NDCDTVFAACSLVPGSFKCECIQGFRGAG  229
            N C    A C   PGSF C C  G+ G G
Sbjct  900  NRCHPA-ATCYNTPGSFSCRCQPGYYGDG  927


 Score = 48.9 bits (115),  Expect = 1e-05, Method: Compositional matrix adjust.
 Identities = 30/86 (34%), Positives = 47/86 (54%), Gaps = 4/86 (4%)

Query  150  INECNENPSICPSNSVCTNLAG-SYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFA  208
            +N C +   +C + + C    G  Y CEC++G++ D  G  CV E+ C TG + C    +
Sbjct  761  VNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGD--GRNCVDENECATGFHRCGPN-S  817

Query  209  ACSLVPGSFKCECIQGFRGAGTVNTC  234
             C  +PGS++CEC  G+  A   +TC
Sbjct  818  VCINLPGSYRCECRSGYEFADDRHTC  843


> CE05481
Length=838

 Score = 60.8 bits (146),  Expect = 4e-09, Method: Compositional matrix adjust.
 Identities = 49/161 (30%), Positives = 73/161 (45%), Gaps = 15/161 (9%)

Query  23   DHCSRVEHAESCQSGDGFWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDCVNI  82
            DHC          S   + C C+ G+     N    CIDIDEC +G      +   CVN 
Sbjct  164  DHCDLRTSFCKSNSKFNYTCECRSGYEK---NQYGECIDIDEC-RGYKAVCDRNAWCVNE  219

Query  83   PGSFTCGC-GPYRQE-KDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNN  140
             GS+ C C   YR + K    + +   S +  +C  ++ C+N      +C+C +G+ G+ 
Sbjct  220  IGSYKCECMASYRGDGKHCTYVGLGRSSIDCKDCSMHATCMN-----GVCQCKEGYEGD-  273

Query  141  DKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGF  181
                  C D+NEC   P +C  N+ C N  GS+ C C  G+
Sbjct  274  ---GFNCTDVNECLRRPEMCNKNAECINREGSFICTCLEGY  311


 Score = 46.2 bits (108),  Expect = 9e-05, Method: Compositional matrix adjust.
 Identities = 36/113 (31%), Positives = 51/113 (45%), Gaps = 12/113 (10%)

Query  130  CKCHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSG  189
            C+C  G+  N       C DI+EC    ++C  N+ C N  GSYKCEC A +  D  G  
Sbjct  183  CECRSGYEKNQ---YGECIDIDECRGYKAVCDRNAWCVNEIGSYKCECMASYRGD--GKH  237

Query  190  CVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGFRGAG----TVNTCEPLP  238
            C    + G G++  D    +      +  C+C +G+ G G     VN C   P
Sbjct  238  CT---YVGLGRSSIDCKDCSMHATCMNGVCQCKEGYEGDGFNCTDVNECLRRP  287


> Hs20543258
Length=1375

 Score = 60.5 bits (145),  Expect = 5e-09, Method: Compositional matrix adjust.
 Identities = 55/184 (29%), Positives = 77/184 (41%), Gaps = 28/184 (15%)

Query  22   YDHCSRVEHAESCQSGDG--FWCACQKGFTPQGINLSSTCIDIDECAQGLDNCKQKGGDC  79
            YD     +    C  G G  + C C  G+   G N    C+D +ECA G   C      C
Sbjct  764  YDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRN----CVDENECATGFHRCG-PNSVC  818

Query  80   VNIPGSFTCGC--GPYRQEKDGVCIDI----NECSTNRGNCDE--NSDCINLDGEEQLCK  131
            +N+PGS+ C C  G    +    CI I    N C      C     + C++  G    C 
Sbjct  819  INLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCA  878

Query  132  CHKGWTGNNDKPNVACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFE-------PD  184
            C  G+ G+  +    C D++EC+EN   C   + C N  GS+ C C  G+        PD
Sbjct  879  CLPGYAGDGHQ----CTDVDECSEN--RCHPAATCYNTPGSFSCRCQPGYYGDGFQCIPD  932

Query  185  SSGS  188
            S+ S
Sbjct  933  STSS  936


 Score = 56.2 bits (134),  Expect = 9e-08, Method: Compositional matrix adjust.
 Identities = 49/149 (32%), Positives = 65/149 (43%), Gaps = 11/149 (7%)

Query  86   FTCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPN-  144
            +TC C    Q     C+D NEC+T    C  NS CINL G  + C+C  G+   +D+   
Sbjct  784  YTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYR-CECRSGYEFADDRHTC  842

Query  145  -VACRDINECNENPSICPS--NSVCTNLAGS-YKCECSAGFEPDSSGSGCVTEDFCGTGK  200
             +     N C +    C     + C +  GS + C C  G+  D  G  C   D C   +
Sbjct  843  ILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGD--GHQCTDVDEC--SE  898

Query  201  NDCDTVFAACSLVPGSFKCECIQGFRGAG  229
            N C    A C   PGSF C C  G+ G G
Sbjct  899  NRCHPA-ATCYNTPGSFSCRCQPGYYGDG  926


 Score = 55.5 bits (132),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 46/151 (30%), Positives = 65/151 (43%), Gaps = 12/151 (7%)

Query  85   SFTCGCGPYRQEKDGVCIDINECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPN  144
            + T   GP +++ D      N C      CD  + C    G +  C+C  G+ G+     
Sbjct  743  AVTNQIGPVKEDSDPT--PGNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRN--  798

Query  145  VACRDINECNENPSICPSNSVCTNLAGSYKCECSAGFEPDSSGSGCV----TEDFCGTGK  200
              C D NEC      C  NSVC NL GSY+CEC +G+E       C+      + C  G 
Sbjct  799  --CVDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGS  856

Query  201  NDCDTVFAACSLVPG--SFKCECIQGFRGAG  229
            + C     A  +  G  +F C C+ G+ G G
Sbjct  857  HTCAPAGQARCVHHGGSTFSCACLPGYAGDG  887


 Score = 47.4 bits (111),  Expect = 4e-05, Method: Compositional matrix adjust.
 Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 4/85 (4%)

Query  151  NECNENPSICPSNSVCTNLAG-SYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAA  209
            N C +   +C + + C    G  Y CEC++G++ D  G  CV E+ C TG + C    + 
Sbjct  761  NPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGD--GRNCVDENECATGFHRCGPN-SV  817

Query  210  CSLVPGSFKCECIQGFRGAGTVNTC  234
            C  +PGS++CEC  G+  A   +TC
Sbjct  818  CINLPGSYRCECRSGYEFADDRHTC  842


> Hs4885229
Length=4590

 Score = 60.5 bits (145),  Expect = 5e-09, Method: Composition-based stats.
 Identities = 55/179 (30%), Positives = 76/179 (42%), Gaps = 41/179 (22%)

Query  6     LAAMGGKSSTPCDAGGYDHCSRVEHAESCQSGDGFWCACQKGFTPQGINLSSTC-IDIDE  64
             L A    +S PC  GG  + S            G++C C        + + + C I ++ 
Sbjct  4013  LTATEDCASNPCQNGGVCNPS---------PAGGYYCKCS------ALYIGTHCEISVNP  4057

Query  65    CAQGLDNCKQKGGDCVNIPGSFTCGC-GPY---RQEKDGVCIDINECSTNRGNCDENSDC  120
             C+    N    GG CV   G F C C G Y   R +    C D  E   N G C ++   
Sbjct  4058  CSS---NPCLYGGTCVVDNGGFVCQCRGLYTGQRCQLSPYCKD--EPCKNGGTCFDS---  4109

Query  121   INLDGEEQLCKCHKGWTGNNDKPNVACR-DINECNENPSICPSNSVCTNLAGSYKCECS  178
               LDG   +C+C  G+ G        C+ DI+EC+ NP  C   ++C N  GSY C CS
Sbjct  4110  --LDG--AVCQCDSGFRGER------CQSDIDECSGNP--CLHGALCENTHGSYHCNCS  4156


 Score = 38.1 bits (87),  Expect = 0.028, Method: Composition-based stats.
 Identities = 46/209 (22%), Positives = 75/209 (35%), Gaps = 31/209 (14%)

Query  106   ECSTNRGNCDENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDINECNENPSICPSNSV  165
             +C++N   C     C         CKC   + G + + +V     N C+ NP  C     
Sbjct  4018  DCASN--PCQNGGVCNPSPAGGYYCKCSALYIGTHCEISV-----NPCSSNP--CLYGGT  4068

Query  166   CTNLAGSYKCECSAGFEPDSSGSGCVTEDFCGTGKNDCDTVFAACSLVPGSFKCECIQGF  225
             C    G + C+C   +    +G  C    +C      C         + G+  C+C  GF
Sbjct  4069  CVVDNGGFVCQCRGLY----TGQRCQLSPYCK--DEPCKNGGTCFDSLDGAV-CQCDSGF  4121

Query  226   RGAGTVNTCEPLPGNEDLACTTLGLTCGDYKYCTKSTTQAGLWECTDKAASEQLAVFIAN  285
             RG    +  +   GN  L       T G Y +C  S    G   C D A ++ ++     
Sbjct  4122  RGERCQSDIDECSGNPCLHGALCENTHGSY-HCNCSHEYRGR-HCEDAAPNQYVS-----  4174

Query  286   GATSDTPSWVWAVVVLSTIALILISGGVL  314
                  TP   W + +   I +++   G+ 
Sbjct  4175  -----TP---WNIGLAEGIGIVVFVAGIF  4195


> 7291068_3
Length=3710

 Score = 59.3 bits (142),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 70/244 (28%), Positives = 100/244 (40%), Gaps = 60/244 (24%)

Query  39   GFWCACQKGFTPQGINLSSTC-IDIDECAQGLDNCKQK--GGDCVNIPGSFTCGCGPYRQ  95
            G+ C C+ G+   G  L+  C  D+DEC+   D+   K     C+N+PGSFTC   P   
Sbjct  232  GYRCICEPGWKTNG--LTPICGEDVDECS---DSAAHKPCSTSCINLPGSFTCAPCPAGL  286

Query  96   EKDGV-CIDINECSTNRGNCD--ENSDCINLDGEEQLCKCHKGWTGNNDKPNVACRDIN-  151
              +GV C D++EC TN G C      DCIN  G     +C  GWTG+  K   + +DI+ 
Sbjct  287  TGNGVSCRDLDECQTNNGGCSLSPKVDCINTYGSYHCGECPVGWTGDGRKCERSPQDIDI  346

Query  152  ECNENPSICPS-------NSVCTNLAGSYKCECSAGFEPDSSG-SGCVTEDFCGTGKNDC  203
               + P  CP+        + C  ++G+  C C  G      G +GCV        +N C
Sbjct  347  PAGQTPRTCPAGNNPCYPTASCFLISGTTSCRCPMGMVGTGYGPNGCVNGTTTNCKENPC  406

Query  204  DT----VFAACS----LVPGSFK--------------------------------CECIQ  223
                  +FA  S    L P  F+                                C+C+ 
Sbjct  407  LNGGICLFAGPSNYTCLCPIGFRPPICEPQPSPCDQHPCKNGGRCRPTTSGDLFVCQCLP  466

Query  224  GFRG  227
            G+RG
Sbjct  467  GYRG  470


 Score = 55.8 bits (133),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 68/236 (28%), Positives = 102/236 (43%), Gaps = 48/236 (20%)

Query  39   GFWCACQKGFTPQGINLSSTC-IDIDECA--QGLDNCKQKGGDCVNIPGSFTCGCGPYRQ  95
            GF C C+  F        + C +D++ECA  +G D   Q GG C N  G+++C C P   
Sbjct  146  GFRCQCRSAFE------GTKCEMDVNECALYEGTDLGCQNGGQCQNHFGTYSCLCQPGWH  199

Query  96   EKDGVCIDINECSTNRGNCDENS--------DCI-NLDGEEQLCKCHKGWTGNNDKPNVA  146
                       C+  + +C ++S         C+ + D     C C  GW  N   P + 
Sbjct  200  GM--------HCTQRKADCSQSSAWELCGHGSCVPSADDAGYRCICEPGWKTNGLTP-IC  250

Query  147  CRDINECNENPSICPSNSVCTNLAGSYKCE-CSAGFEPDSSGSGCVTEDFCGTGKNDCDT  205
              D++EC+++ +  P ++ C NL GS+ C  C AG     +G+G    D      ++C T
Sbjct  251  GEDVDECSDSAAHKPCSTSCINLPGSFTCAPCPAGL----TGNGVSCRDL-----DECQT  301

Query  206  VFAACSLVP--------GSFKC-ECIQGFRGAGTVNTCEPLPGNEDLACTTLGLTC  252
                CSL P        GS+ C EC  G+ G G    CE  P + D+       TC
Sbjct  302  NNGGCSLSPKVDCINTYGSYHCGECPVGWTGDG--RKCERSPQDIDIPAGQTPRTC  355


> Hs4507833
Length=640

 Score = 58.5 bits (140),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 40/101 (39%), Positives = 55/101 (54%), Gaps = 9/101 (8%)

Query  42   CACQKGFTPQGINLSSTCIDIDECA-QGLDNCKQKGGDCVNIPGSFTCGCGP-YRQEKDG  99
            C CQ+GFT  G+    TC+D+DECA  G  NC      CVN PGSF+C C   +R     
Sbjct  50   CTCQEGFTGDGL----TCVDLDECAIPGAHNCSANSS-CVNTPGSFSCVCPEGFRLSPGL  104

Query  100  VCIDINECST-NRGNCDENSDCINLDGEEQLCKCHKGWTGN  139
             C D++EC+     +C   + C+N+ G   LC C  G+ G+
Sbjct  105  GCTDVDECAEPGLSHCHALATCVNVVG-SYLCVCPAGYRGD  144



Lambda     K      H
   0.318    0.136    0.457 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 7953438556


  Database: kyva
    Posted date:  Jul 3, 2009  9:03 AM
  Number of letters in database: 47,500,486
  Number of sequences in database:  112,920



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40