bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
164,496 sequences; 82,071,388 total letters
Query= Emax_3129_orf1
Length=109
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_094280 E3 ubiquitin-protein ligase, putative 116 1e-26
hsa:7337 UBE3A, ANCR, AS, E6-AP, EPVE6AP, FLJ26981, HPVE6A; ub... 100 1e-21
mmu:22215 Ube3a, 4732496B02, 5830462N02Rik, A130086L21Rik, Hpv... 99.4 2e-21
xla:380385 ube3a, MGC53073; ubiquitin protein ligase E3A (huma... 97.8 8e-21
dre:792398 ube3a, MGC174322, MGC92173, im:7140733, zgc:92173; ... 91.7 5e-19
cpv:cgd6_2490 e3 ubiquitin-protein ligase 81.6 6e-16
mmu:226098 Hectd2, 4921524L07, A630025O09Rik, AW212605; HECT d... 81.3 8e-16
dre:564866 im:7149446; si:ch211-272f3.4; K10590 E3 ubiquitin-p... 79.7 2e-15
hsa:9320 TRIP12, KIAA0045, MGC138849, MGC138850, ULF; thyroid ... 76.6 2e-14
mmu:14897 Trip12, 1110036I07Rik, 6720416K24Rik, AA410158, Gtl6... 75.9 3e-14
xla:414478 hypothetical protein MGC83258; K10590 E3 ubiquitin-... 75.9 3e-14
dre:562999 ubiquitin protein ligase E3A-like; K12232 E3 ubiqui... 75.5 3e-14
dre:100003587 si:ch73-190m4.3; K10614 E3 ubiquitin-protein lig... 72.0 4e-13
mmu:67345 Herc4, 1700056O17Rik, 4921531D01Rik, 9530080M15Rik, ... 71.6 5e-13
dre:557513 herc4; hect domain and RLD 4; K10615 E3 ubiquitin-p... 71.2 7e-13
hsa:26091 HERC4, DKFZp564G092, KIAA1593; hect domain and RLD 4... 70.1 1e-12
dre:559981 si:ch73-190m4.1 68.6 4e-12
mmu:94253 Hecw1, 9330116H24Rik, AV273951, E130207I19Rik, Nedl1... 68.6 5e-12
xla:380493 ube3c, MGC52671, kiaa0010; ubiquitin protein ligase... 68.2 6e-12
hsa:9690 UBE3C, KIAA0010, KIAA10; ubiquitin protein ligase E3C... 68.2 7e-12
hsa:23072 HECW1, KIAA0322, NEDL1; HECT, C2 and WW domain conta... 68.2 7e-12
tgo:TGME49_022430 ubiquitin-transferase domain containing prot... 67.8 7e-12
dre:100334952 NEDD4-like ubiquitin-protein ligase 1-like 67.4 1e-11
mmu:100763 Ube3c, AI853514, mKIAA0010; ubiquitin protein ligas... 67.0 1e-11
dre:100150269 HECT, C2 and WW domain containing E3 ubiquitin p... 67.0 1e-11
xla:444030 herc3, MGC82587; hect domain and RLD 3; K10614 E3 u... 66.6 2e-11
hsa:57520 HECW2, DKFZp686M17164, NEDL2; HECT, C2 and WW domain... 66.6 2e-11
xla:444182 herc6, MGC80684; hect domain and RLD 6 66.2
mmu:329152 Hecw2, A730039N16Rik, D030049F17Rik, Gm971, Nedl2, ... 65.9 3e-11
dre:563730 si:ch211-106n13.1; K12167 E3 ubiquitin-protein liga... 65.5 4e-11
tpv:TP02_0025 ubiquitin-protein ligase; K10589 ubiquitin-prote... 65.5 5e-11
ath:AT5G02880 UPL4; UPL4; ubiquitin-protein ligase 63.9 1e-10
hsa:51191 HERC5, CEB1, CEBP1; hect domain and RLD 5 63.2
dre:100148091 similar to hect domain and RLD 4 62.8
dre:794323 similar to hect domain and RLD 4 62.4
hsa:8916 HERC3, KIAA0032; hect domain and RLD 3; K10614 E3 ubi... 62.4 3e-10
mmu:73998 Herc3, 5730409F18Rik, AI646603, MGC30404, mKIAA0032;... 62.0 5e-10
sce:YKL010C UFD4; Ubiquitin-protein ligase (E3) that interacts... 62.0 5e-10
ath:AT4G38600 KAK; KAK (KAKTUS); ubiquitin-protein ligase; K10... 62.0 5e-10
tpv:TP01_0229 ubiquitin-protein ligase 60.5 1e-09
dre:100073325 zgc:163136 59.7 2e-09
cpv:cgd8_1200 E3A like HECT domain containing ubiquitin protei... 59.3 3e-09
hsa:79654 HECTD3, FLJ21156, FLJ31983, MGC161630, RP11-69J16.1;... 59.3 3e-09
cel:Y39A1C.2 oxi-1; OXidative stress Induced family member (ox... 59.3 3e-09
pfa:MAL8P1.23 ubiquitin-protein ligase 1, putative; K10592 E3 ... 58.9 4e-09
cel:Y48G8AL.1 hypothetical protein 58.5 5e-09
hsa:4734 NEDD4, KIAA0093, MGC176705, NEDD4-1, RPF1; neural pre... 58.5 5e-09
mmu:76608 Hectd3, 1700064K09Rik, AI467540, AW743312; HECT doma... 58.5 6e-09
hsa:55008 HERC6, FLJ20637; hect domain and RLD 6 58.5
sce:YJR036C HUL4; Hul4p (EC:6.3.2.-); K12232 E3 ubiquitin-prot... 58.2 6e-09
> tgo:TGME49_094280 E3 ubiquitin-protein ligase, putative
Length=902
Score = 116 bits (291), Expect = 1e-26, Method: Compositional matrix adjust.
Identities = 51/109 (46%), Positives = 74/109 (67%), Gaps = 0/109 (0%)
Query 1 ASQFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLA 60
A Q+ F+ GF RC+D T+SL P+ELQ ++LGS++E++ L AT YQDGY+ +S
Sbjct 754 AEQYRHFEEGFLRCVDEATISLFRPEELQQVILGSEEELNFDKLRSATSYQDGYTAESQT 813
Query 61 IRRLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHGFDTD 109
++ WA+ QK++ LMFVTGSDR+P+ G +L+ IGR+G DTD
Sbjct 814 VQDFWAVADALDSVQKKKLLMFVTGSDRVPIKGLSSLKFVIGRNGSDTD 862
> hsa:7337 UBE3A, ANCR, AS, E6-AP, EPVE6AP, FLJ26981, HPVE6A;
ubiquitin protein ligase E3A (EC:6.3.2.19); K10587 ubiquitin-protein
ligase E3 A [EC:6.3.2.19]
Length=875
Score = 100 bits (249), Expect = 1e-21, Method: Composition-based stats.
Identities = 48/108 (44%), Positives = 69/108 (63%), Gaps = 2/108 (1%)
Query 3 QFAAFKRGFFRCLDSNTLSLLL-PQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAI 61
QF AF+RGF + + L L P+E++LL+ GS+ + L + T Y GY+ DS+ I
Sbjct 729 QFKAFRRGFHMVTNESPLKYLFRPEEIELLICGSRN-LDFQALEETTEYDGGYTRDSVLI 787
Query 62 RRLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHGFDTD 109
R W I+ +FTD+QKR FL F TG+DR PVGG L++ I ++G DT+
Sbjct 788 REFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKLKMIIAKNGPDTE 835
> mmu:22215 Ube3a, 4732496B02, 5830462N02Rik, A130086L21Rik, Hpve6a,
KIAA4216, mKIAA4216; ubiquitin protein ligase E3A (EC:6.3.2.19);
K10587 ubiquitin-protein ligase E3 A [EC:6.3.2.19]
Length=849
Score = 99.4 bits (246), Expect = 2e-21, Method: Composition-based stats.
Identities = 47/108 (43%), Positives = 69/108 (63%), Gaps = 2/108 (1%)
Query 3 QFAAFKRGFFRCLDSNTLSLLL-PQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAI 61
QF AF+RGF + + L L P+E++LL+ GS+ + L + T Y GY+ +S+ I
Sbjct 703 QFKAFRRGFHMVTNESPLKYLFRPEEIELLICGSRN-LDFQALEETTEYDGGYTRESVVI 761
Query 62 RRLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHGFDTD 109
R W I+ +FTD+QKR FL F TG+DR PVGG L++ I ++G DT+
Sbjct 762 REFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKLKMIIAKNGPDTE 809
> xla:380385 ube3a, MGC53073; ubiquitin protein ligase E3A (human
papilloma virus E6-associated protein, Angelman syndrome);
K10587 ubiquitin-protein ligase E3 A [EC:6.3.2.19]
Length=908
Score = 97.8 bits (242), Expect = 8e-21, Method: Composition-based stats.
Identities = 47/108 (43%), Positives = 68/108 (62%), Gaps = 2/108 (1%)
Query 3 QFAAFKRGFFRCLDSNTLSLLL-PQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAI 61
QF AF+RGF + + L L P+E++LL+ GS+ + L T Y GY+ DS I
Sbjct 762 QFKAFRRGFHMVTNESPLKYLFRPEEIELLICGSRN-VDFQALKDTTEYDGGYTRDSNII 820
Query 62 RRLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHGFDTD 109
+ W I+++FT++QKR FL F TG+DR PVGG L++ I ++G DTD
Sbjct 821 KEFWEIVNSFTEEQKRLFLQFTTGTDRAPVGGLGKLKMIIAKNGPDTD 868
> dre:792398 ube3a, MGC174322, MGC92173, im:7140733, zgc:92173;
ubiquitin protein ligase E3A (EC:6.3.2.19); K10587 ubiquitin-protein
ligase E3 A [EC:6.3.2.19]
Length=857
Score = 91.7 bits (226), Expect = 5e-19, Method: Composition-based stats.
Identities = 44/108 (40%), Positives = 67/108 (62%), Gaps = 2/108 (1%)
Query 3 QFAAFKRGFFRCLDSNTLSLLL-PQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAI 61
QF AF+RGF + + L L P+E++LL+ GS+ + L ++T Y GY++DS I
Sbjct 711 QFKAFRRGFHMVTNESPLKYLFRPEEIELLICGSRN-LDFQALEESTEYDGGYNKDSRII 769
Query 62 RRLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHGFDTD 109
R W + +F ++KR FL F TG+DR PVGG L++ I ++G D+D
Sbjct 770 RDFWETVHSFEQEKKRLFLQFTTGTDRAPVGGLGKLKMIIAKNGPDSD 817
> cpv:cgd6_2490 e3 ubiquitin-protein ligase
Length=797
Score = 81.6 bits (200), Expect = 6e-16, Method: Composition-based stats.
Identities = 46/108 (42%), Positives = 65/108 (60%), Gaps = 1/108 (0%)
Query 2 SQFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAI 61
SQF AF GF TL L P+EL L++ GS + ++ L +A++YQDGY++DS +
Sbjct 651 SQFRAFYNGFQSVCGGRTLELFSPEELVLVICGSS-DFNIDSLIEASQYQDGYTKDSTTV 709
Query 62 RRLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHGFDTD 109
W I+ K +++ L FVTGSDR+P+ G L IGRHG D+D
Sbjct 710 VMFWEIVKKLDLKLQKKLLFFVTGSDRVPMKGLGELGFVIGRHGPDSD 757
> mmu:226098 Hectd2, 4921524L07, A630025O09Rik, AW212605; HECT
domain containing 2 (EC:6.3.2.-); K12232 E3 ubiquitin-protein
ligase HECTD2 [EC:6.3.2.19]
Length=775
Score = 81.3 bits (199), Expect = 8e-16, Method: Composition-based stats.
Identities = 43/107 (40%), Positives = 65/107 (60%), Gaps = 2/107 (1%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIR 62
QFAAF GF SN L LL P+E+++L+ GS E+ + L ++T+Y DGY++ L IR
Sbjct 631 QFAAFYCGFHSVCASNALMLLRPEEVEILVCGSP-ELDMHALQRSTQY-DGYAKTDLTIR 688
Query 63 RLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHGFDTD 109
W ++ F + +++ L F TGSDR+PVGG L I ++ T+
Sbjct 689 YFWDVVLGFPLELQKKLLHFTTGSDRVPVGGMADLNFKISKNETSTN 735
> dre:564866 im:7149446; si:ch211-272f3.4; K10590 E3 ubiquitin-protein
ligase TRIP12 [EC:6.3.2.19]
Length=1688
Score = 79.7 bits (195), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 47/109 (43%), Positives = 65/109 (59%), Gaps = 3/109 (2%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEI-SLAVLHKATRYQDGYSEDSLAI 61
QF +F+ GF + L P+EL LL GS+ E + L + R GY+ DS A+
Sbjct 1533 QFESFREGFESVFPLHHLQYFYPEELDQLLCGSKSESWDVKTLMECCRPDHGYTHDSRAV 1592
Query 62 RRLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALR--LTIGRHGFDT 108
R L+ +LS+F +Q+R FL FVTGS RLPVGG ++L LTI R F++
Sbjct 1593 RFLFEVLSSFDAEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFES 1641
> hsa:9320 TRIP12, KIAA0045, MGC138849, MGC138850, ULF; thyroid
hormone receptor interactor 12; K10590 E3 ubiquitin-protein
ligase TRIP12 [EC:6.3.2.19]
Length=1992
Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 46/109 (42%), Positives = 65/109 (59%), Gaps = 3/109 (2%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEI-SLAVLHKATRYQDGYSEDSLAI 61
QF +F+ GF + L P+EL LL GS+ + L + R GY+ DS A+
Sbjct 1837 QFDSFRDGFESVFPLSHLQYFYPEELDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAV 1896
Query 62 RRLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALR--LTIGRHGFDT 108
+ L+ ILS+F ++Q+R FL FVTGS RLPVGG ++L LTI R F++
Sbjct 1897 KFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFES 1945
> mmu:14897 Trip12, 1110036I07Rik, 6720416K24Rik, AA410158, Gtl6,
MGC31615; thyroid hormone receptor interactor 12; K10590
E3 ubiquitin-protein ligase TRIP12 [EC:6.3.2.19]
Length=2025
Score = 75.9 bits (185), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 46/109 (42%), Positives = 64/109 (58%), Gaps = 3/109 (2%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEI-SLAVLHKATRYQDGYSEDSLAI 61
QF +F+ GF L P+EL LL GS+ + L + R GY+ DS A+
Sbjct 1870 QFDSFRDGFESVFPLCHLQYFYPEELDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAV 1929
Query 62 RRLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALR--LTIGRHGFDT 108
+ L+ ILS+F ++Q+R FL FVTGS RLPVGG ++L LTI R F++
Sbjct 1930 KFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFES 1978
> xla:414478 hypothetical protein MGC83258; K10590 E3 ubiquitin-protein
ligase TRIP12 [EC:6.3.2.19]
Length=2027
Score = 75.9 bits (185), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 46/108 (42%), Positives = 63/108 (58%), Gaps = 3/108 (2%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEI-SLAVLHKATRYQDGYSEDSLAI 61
Q +F+ GF N L P+EL LL GS+ + + L + R GY+ DS A+
Sbjct 1872 QLDSFRDGFESVFPLNHLQYFYPEELDQLLCGSRADPWDVKTLMECCRPDHGYTHDSRAV 1931
Query 62 RRLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALR--LTIGRHGFD 107
+ L+ ILS+F +Q+R FL FVTGS RLPVGG ++L LTI R F+
Sbjct 1932 KFLFEILSSFDKEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFE 1979
> dre:562999 ubiquitin protein ligase E3A-like; K12232 E3 ubiquitin-protein
ligase HECTD2 [EC:6.3.2.19]
Length=780
Score = 75.5 bits (184), Expect = 3e-14, Method: Composition-based stats.
Identities = 41/107 (38%), Positives = 60/107 (56%), Gaps = 2/107 (1%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIR 62
QFAAF GF SN L LL P+E+++L+ GS + + L + +Y+ GYS+ IR
Sbjct 636 QFAAFYHGFHSVCASNALMLLRPEEVEILVCGSPN-LDMGSLQRVVQYE-GYSKTDPTIR 693
Query 63 RLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHGFDTD 109
W ++ F + +++ L F TGSDR+PVGG L I + TD
Sbjct 694 AFWDVVLAFPLELQKKLLHFTTGSDRVPVGGMADLNFKISKIDVSTD 740
> dre:100003587 si:ch73-190m4.3; K10614 E3 ubiquitin-protein ligase
HERC3 [EC:6.3.2.19]
Length=1046
Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 56/99 (56%), Gaps = 1/99 (1%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIR 62
Q++AF GF + LSL P EL +++G+ + + K Y+ +S ++
Sbjct 901 QYSAFSSGFLKVCGGEILSLFQPSELMAMVVGNNN-YNWEEMEKNASYKGEFSATHPTVK 959
Query 63 RLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTI 101
W + F+ ++K+QFL+F+TGSDR+P+ G +LR+ I
Sbjct 960 MFWEVFHEFSLEKKKQFLLFLTGSDRIPIHGMASLRIVI 998
> mmu:67345 Herc4, 1700056O17Rik, 4921531D01Rik, 9530080M15Rik,
mKIAA1593; hect domain and RLD 4; K10615 E3 ubiquitin-protein
ligase HERC4 [EC:6.3.2.19]
Length=1049
Score = 71.6 bits (174), Expect = 5e-13, Method: Composition-based stats.
Identities = 38/105 (36%), Positives = 56/105 (53%), Gaps = 1/105 (0%)
Query 1 ASQFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLA 60
AS F AF GF + L L P ELQ +++G+ L K T Y+ Y D
Sbjct 902 ASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTN-YDWKELEKNTEYKGEYWADHPT 960
Query 61 IRRLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHG 105
I+ W + ++K+QFL+F+TGSDR+P+ G ++L+L I G
Sbjct 961 IKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSLKLVIQSTG 1005
> dre:557513 herc4; hect domain and RLD 4; K10615 E3 ubiquitin-protein
ligase HERC4 [EC:6.3.2.19]
Length=1053
Score = 71.2 bits (173), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 36/101 (35%), Positives = 54/101 (53%), Gaps = 1/101 (0%)
Query 1 ASQFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLA 60
A QF+AF GF + L L P ELQ +++G+ L K Y+ Y D
Sbjct 906 APQFSAFYAGFHKVCGGKVLELFQPSELQAMVIGNTN-YDWKELEKNLEYKGEYWADHPT 964
Query 61 IRRLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTI 101
I+ W + ++K+QFL+F+TGSDR+P+ G ++L L I
Sbjct 965 IKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSLALVI 1005
> hsa:26091 HERC4, DKFZp564G092, KIAA1593; hect domain and RLD
4; K10615 E3 ubiquitin-protein ligase HERC4 [EC:6.3.2.19]
Length=1049
Score = 70.1 bits (170), Expect = 1e-12, Method: Composition-based stats.
Identities = 37/105 (35%), Positives = 56/105 (53%), Gaps = 1/105 (0%)
Query 1 ASQFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLA 60
AS F AF GF + L L P ELQ +++G+ L K T Y+ Y +
Sbjct 902 ASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTN-YDWKELEKNTEYKGEYWAEHPT 960
Query 61 IRRLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHG 105
I+ W + ++K+QFL+F+TGSDR+P+ G ++L+L I G
Sbjct 961 IKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSLKLVIQSTG 1005
> dre:559981 si:ch73-190m4.1
Length=630
Score = 68.6 bits (166), Expect = 4e-12, Method: Composition-based stats.
Identities = 30/98 (30%), Positives = 58/98 (59%), Gaps = 1/98 (1%)
Query 4 FAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIRR 63
F F+RGFFR + + + P+EL+ +L+G++ E +L + T Y+ ++ D I
Sbjct 485 FEEFRRGFFRGCEKRLVEMFEPEELRGVLVGNE-EYDWNILKQNTTYEGVFNADHPVIIS 543
Query 64 LWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTI 101
W + + T +K+ FL+F+TG +R+P+ G A+++ +
Sbjct 544 FWEVFDDLTPNEKKSFLLFLTGFERVPILGMSAVKMRV 581
> mmu:94253 Hecw1, 9330116H24Rik, AV273951, E130207I19Rik, Nedl1;
HECT, C2 and WW domain containing E3 ubiquitin protein ligase
1; K12167 E3 ubiquitin-protein ligase HECW1 [EC:6.3.2.19]
Length=1604
Score = 68.6 bits (166), Expect = 5e-12, Method: Composition-based stats.
Identities = 38/104 (36%), Positives = 57/104 (54%), Gaps = 1/104 (0%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIR 62
Q A RGF+ +DS +S+ +EL+L++ G+ EI L T Y+ GY + L IR
Sbjct 1453 QTEALLRGFYEVVDSRLVSVFDARELELVIAGTA-EIDLNDWRNNTEYRGGYHDGHLVIR 1511
Query 63 RLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHGF 106
WA + F ++Q+ + L FVTG+ +P G ALR + G F
Sbjct 1512 WFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRF 1555
> xla:380493 ube3c, MGC52671, kiaa0010; ubiquitin protein ligase
E3C; K10589 ubiquitin-protein ligase E3 C [EC:6.3.2.19]
Length=1080
Score = 68.2 bits (165), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 36/104 (34%), Positives = 55/104 (52%), Gaps = 0/104 (0%)
Query 6 AFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIRRLW 65
AF++G ++ L + QE+Q+L+ G+Q I L L T Y GY+ D I+ W
Sbjct 935 AFRQGLANVVNLEWLRMFDQQEIQVLISGAQVPICLDDLKSFTNYSGGYTADHPVIKIFW 994
Query 66 AILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHGFDTD 109
++ NFTD++KR+ L FVT R P+ G + L H +D
Sbjct 995 RVVENFTDEEKRKLLKFVTSCSRPPLLGFKELYPAFCIHNGGSD 1038
> hsa:9690 UBE3C, KIAA0010, KIAA10; ubiquitin protein ligase E3C;
K10589 ubiquitin-protein ligase E3 C [EC:6.3.2.19]
Length=1083
Score = 68.2 bits (165), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 37/104 (35%), Positives = 54/104 (51%), Gaps = 0/104 (0%)
Query 6 AFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIRRLW 65
AF++G + L + QE+Q+L+ G+Q ISL L T Y GYS D I+ W
Sbjct 938 AFRQGLANVVSLEWLRMFDQQEIQVLISGAQVPISLEDLKSFTNYSGGYSADHPVIKVFW 997
Query 66 AILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHGFDTD 109
++ FTD++KR+ L FVT R P+ G + L H +D
Sbjct 998 RVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELYPAFCIHNGGSD 1041
> hsa:23072 HECW1, KIAA0322, NEDL1; HECT, C2 and WW domain containing
E3 ubiquitin protein ligase 1; K12167 E3 ubiquitin-protein
ligase HECW1 [EC:6.3.2.19]
Length=1606
Score = 68.2 bits (165), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 37/100 (37%), Positives = 56/100 (56%), Gaps = 1/100 (1%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIR 62
Q A RGF+ +DS +S+ +EL+L++ G+ EI L T Y+ GY + L IR
Sbjct 1455 QTEALVRGFYEVVDSRLVSVFDARELELVIAGTA-EIDLNDWRNNTEYRGGYHDGHLVIR 1513
Query 63 RLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIG 102
WA + F ++Q+ + L FVTG+ +P G ALR + G
Sbjct 1514 WFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNG 1553
> tgo:TGME49_022430 ubiquitin-transferase domain containing protein
(EC:4.2.1.1)
Length=1629
Score = 67.8 bits (164), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 41/105 (39%), Positives = 61/105 (58%), Gaps = 3/105 (2%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIR 62
Q+ AF+RGF C S S L ELQLL+ G+ E+ L + + + G+ D I
Sbjct 1485 QYDAFERGFLLC-SSPLTSQLSGLELQLLICGTP-ELDFRQLRDSAKVE-GFDADDPYIE 1541
Query 63 RLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHGFD 107
W ILS+F QK++FL FVTGSDR P G + +R+++ ++G +
Sbjct 1542 SFWKILSSFDIFQKQKFLKFVTGSDRAPAFGLKEIRMSVQKNGVE 1586
> dre:100334952 NEDD4-like ubiquitin-protein ligase 1-like
Length=1304
Score = 67.4 bits (163), Expect = 1e-11, Method: Composition-based stats.
Identities = 36/104 (34%), Positives = 58/104 (55%), Gaps = 1/104 (0%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIR 62
Q A RGF+ +DS +S+ +EL+L++ G+ EI L+ T Y+ GY + + +R
Sbjct 1153 QAEALVRGFYEVVDSRLVSVFDARELELVIAGTA-EIDLSDWRSNTEYRGGYHDGHMVMR 1211
Query 63 RLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHGF 106
WA + F ++Q+ + L FVTG+ +P G ALR + G F
Sbjct 1212 WFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRF 1255
> mmu:100763 Ube3c, AI853514, mKIAA0010; ubiquitin protein ligase
E3C; K10589 ubiquitin-protein ligase E3 C [EC:6.3.2.19]
Length=1083
Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 36/104 (34%), Positives = 54/104 (51%), Gaps = 0/104 (0%)
Query 6 AFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIRRLW 65
AF++G + L + QE+Q+L+ G+Q +SL L T Y GYS D I+ W
Sbjct 938 AFRQGLANVVSLEWLRMFDQQEIQVLISGAQVPVSLEDLKSFTNYSGGYSADHPVIKIFW 997
Query 66 AILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHGFDTD 109
++ FTD++KR+ L FVT R P+ G + L H +D
Sbjct 998 RVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELYPAFCIHNGGSD 1041
> dre:100150269 HECT, C2 and WW domain containing E3 ubiquitin
protein ligase 2-like; K12168 E3 ubiquitin-protein ligase HECW2
[EC:6.3.2.19]
Length=1474
Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 35/106 (33%), Positives = 59/106 (55%), Gaps = 1/106 (0%)
Query 1 ASQFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLA 60
A Q + RGF+ +D +S+ +EL+L++ G+ EI L+ T Y+ GY ++ +
Sbjct 1321 AQQTESLVRGFYEVVDVRLVSVFDARELELVIAGTA-EIDLSDWRNNTEYRGGYHDNHIV 1379
Query 61 IRRLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHGF 106
IR WA + F ++Q+ + L FVTG+ +P G +LR + G F
Sbjct 1380 IRWFWAAVERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRF 1425
> xla:444030 herc3, MGC82587; hect domain and RLD 3; K10614 E3
ubiquitin-protein ligase HERC3 [EC:6.3.2.19]
Length=1050
Score = 66.6 bits (161), Expect = 2e-11, Method: Composition-based stats.
Identities = 31/98 (31%), Positives = 53/98 (54%), Gaps = 1/98 (1%)
Query 4 FAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIRR 63
+ AF GF + L L P EL+ +++GS + L + Y+ YS +R
Sbjct 906 YEAFSTGFLKVCGGKILELFQPSELRSMVVGSNN-YNWQELEENATYKGDYSTSHATVRM 964
Query 64 LWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTI 101
W + +F ++K++FL+F+TGSDR+P+ G +L + I
Sbjct 965 FWEVFHDFPLEKKKKFLLFLTGSDRIPIYGMSSLHIII 1002
> hsa:57520 HECW2, DKFZp686M17164, NEDL2; HECT, C2 and WW domain
containing E3 ubiquitin protein ligase 2; K12168 E3 ubiquitin-protein
ligase HECW2 [EC:6.3.2.19]
Length=1572
Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 34/104 (32%), Positives = 59/104 (56%), Gaps = 1/104 (0%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIR 62
Q + RGF+ +D+ +S+ +EL+L++ G+ EI L+ T Y+ GY ++ + IR
Sbjct 1421 QTESLVRGFYEVVDARLVSVFDARELELVIAGTA-EIDLSDWRNNTEYRGGYHDNHIVIR 1479
Query 63 RLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHGF 106
WA + F ++Q+ + L FVTG+ +P G +LR + G F
Sbjct 1480 WFWAAVERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRF 1523
> xla:444182 herc6, MGC80684; hect domain and RLD 6
Length=1028
Score = 66.2 bits (160), Expect = 3e-11, Method: Composition-based stats.
Identities = 33/102 (32%), Positives = 53/102 (51%), Gaps = 1/102 (0%)
Query 4 FAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIRR 63
F FKRGF++ D + +S P EL+ ++ G+ K T Y Y D I+
Sbjct 883 FEEFKRGFYKVCDKDIISFFQPDELRTVVAGTAN-YDWNTFEKTTIYLGKYRLDHPTIKM 941
Query 64 LWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHG 105
W + + ++K+ FLMF+TG+D+LPV + + + I R G
Sbjct 942 FWKVFHALSLEKKKGFLMFLTGNDKLPVFTSDNVGMKISRFG 983
> mmu:329152 Hecw2, A730039N16Rik, D030049F17Rik, Gm971, Nedl2,
mKIAA1301; HECT, C2 and WW domain containing E3 ubiquitin
protein ligase 2; K12168 E3 ubiquitin-protein ligase HECW2 [EC:6.3.2.19]
Length=1578
Score = 65.9 bits (159), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 34/104 (32%), Positives = 58/104 (55%), Gaps = 1/104 (0%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIR 62
Q + RGF+ +D+ +S+ +EL+L++ G+ EI L T Y+ GY ++ + IR
Sbjct 1427 QTESLVRGFYEVVDARLVSVFDARELELVIAGTA-EIDLNDWRNNTEYRGGYHDNHIVIR 1485
Query 63 RLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHGF 106
WA + F ++Q+ + L FVTG+ +P G +LR + G F
Sbjct 1486 WFWAAVERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRF 1529
> dre:563730 si:ch211-106n13.1; K12167 E3 ubiquitin-protein ligase
HECW1 [EC:6.3.2.19]
Length=1552
Score = 65.5 bits (158), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 35/100 (35%), Positives = 55/100 (55%), Gaps = 1/100 (1%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIR 62
Q A RGF+ +DS +S+ +EL+L++ G+ EI L T Y+ GY + + IR
Sbjct 1401 QTQALVRGFYEVVDSRLVSVFDARELELVIAGTA-EIDLNDWRNNTEYRGGYHDGHIVIR 1459
Query 63 RLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIG 102
W + F ++Q+ + L FVTG+ +P G ALR + G
Sbjct 1460 WFWGAVERFNNEQRLRLLQFVTGTSSVPYEGFTALRGSNG 1499
> tpv:TP02_0025 ubiquitin-protein ligase; K10589 ubiquitin-protein
ligase E3 C [EC:6.3.2.19]
Length=1123
Score = 65.5 bits (158), Expect = 5e-11, Method: Composition-based stats.
Identities = 34/97 (35%), Positives = 54/97 (55%), Gaps = 0/97 (0%)
Query 2 SQFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAI 61
SQ +AF +G + L + P EL+LL+ GS + I ++ L K T Y G+ E++ I
Sbjct 975 SQCSAFLQGLSSIIPLEWLQMFSPSELELLISGSSEAIDISDLRKNTVYAGGFDENNPTI 1034
Query 62 RRLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALR 98
+ LW IL + + ++ FL FVT R P+ G + L+
Sbjct 1035 QWLWEILDEYDNNERSSFLWFVTCCKRSPLMGFKQLQ 1071
> ath:AT5G02880 UPL4; UPL4; ubiquitin-protein ligase
Length=1502
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 40/109 (36%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIR 62
Q AF+ GF + L + +EL+ +L G S+ + ++ GY+ S +
Sbjct 1350 QVEAFRSGFNQVFSIEHLRIFNEEELETMLCGECDLFSMNEVLDHIKFDHGYTSSSPPVE 1409
Query 63 RLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQAL--RLTIGR-HGFDT 108
L IL F +Q+R FL FVTGS RLP GG +L +LTI R HG D+
Sbjct 1410 YLLQILHEFDREQQRAFLQFVTGSPRLPHGGLASLSPKLTIVRKHGSDS 1458
> hsa:51191 HERC5, CEB1, CEBP1; hect domain and RLD 5
Length=1024
Score = 63.2 bits (152), Expect = 2e-10, Method: Composition-based stats.
Identities = 28/97 (28%), Positives = 54/97 (55%), Gaps = 1/97 (1%)
Query 4 FAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIRR 63
+ F+RGF++ D + + L P+EL+ +++G+ + K RY+ GY+ I
Sbjct 881 YEEFRRGFYKMCDEDIIKLFHPEELKDVIVGNT-DYDWKTFEKNARYEPGYNSSHPTIVM 939
Query 64 LWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLT 100
W T ++K++FL+F+TG+DRL + +++T
Sbjct 940 FWKAFHKLTLEEKKKFLVFLTGTDRLQMKDLNNMKIT 976
> dre:100148091 similar to hect domain and RLD 4
Length=992
Score = 62.8 bits (151), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 33/102 (32%), Positives = 56/102 (54%), Gaps = 2/102 (1%)
Query 2 SQFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAI 61
+QF F RGF + + ++ P+ELQ LL GS Q + L ++ Y+ + D L I
Sbjct 845 TQFEQFTRGFSKGCPLDAWTMFHPEELQELLHGSPQ-YNWKELQQSASYEGCSASDEL-I 902
Query 62 RRLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGR 103
+ W + +++ K++FLMF+ G++R+P GG L I +
Sbjct 903 KNFWTVFFELSEENKKKFLMFLYGTERVPAGGLSKRALKISQ 944
> dre:794323 similar to hect domain and RLD 4
Length=985
Score = 62.4 bits (150), Expect = 3e-10, Method: Composition-based stats.
Identities = 32/100 (32%), Positives = 55/100 (55%), Gaps = 2/100 (2%)
Query 2 SQFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAI 61
+QF F RGF + + ++ P+ELQ LL GS Q + ++ Y+ + D L I
Sbjct 838 TQFEQFTRGFSKGCPLDAWTMFHPEELQELLHGSPQ-YNWKEFQQSASYEGCSASDEL-I 895
Query 62 RRLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTI 101
+ W + +++ K++FLMF+ G++R+P GG R+ I
Sbjct 896 KNFWTVFFELSEEHKKKFLMFLYGTERVPAGGFSKRRIKI 935
> hsa:8916 HERC3, KIAA0032; hect domain and RLD 3; K10614 E3 ubiquitin-protein
ligase HERC3 [EC:6.3.2.19]
Length=1050
Score = 62.4 bits (150), Expect = 3e-10, Method: Composition-based stats.
Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 1/98 (1%)
Query 4 FAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIRR 63
+ AF GF + L L P EL+ +++G+ + L + Y+ YS ++
Sbjct 906 YTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSN-YNWEELEETAIYKGDYSATHPTVKL 964
Query 64 LWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTI 101
W F ++K++FL+F+TGSDR+P+ G +L++ I
Sbjct 965 FWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVI 1002
> mmu:73998 Herc3, 5730409F18Rik, AI646603, MGC30404, mKIAA0032;
hect domain and RLD 3; K10614 E3 ubiquitin-protein ligase
HERC3 [EC:6.3.2.19]
Length=1050
Score = 62.0 bits (149), Expect = 5e-10, Method: Composition-based stats.
Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 1/98 (1%)
Query 4 FAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIRR 63
+ AF GF + L L P EL+ +++G+ L + Y+ YS ++
Sbjct 906 YTAFSSGFLKVCGGKVLELFQPAELRAMMVGNSN-YDWEELEETAVYRGDYSSTHPTVKL 964
Query 64 LWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTI 101
W F ++K++FL+F+TGSDR+P+ G +L++ I
Sbjct 965 FWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIII 1002
> sce:YKL010C UFD4; Ubiquitin-protein ligase (E3) that interacts
with Rpt4p and Rpt6p, two subunits of the 19S particle of
the 26S proteasome; cytoplasmic E3 involved in the degradation
of ubiquitin fusion proteins; K10590 E3 ubiquitin-protein
ligase TRIP12 [EC:6.3.2.19]
Length=1483
Score = 62.0 bits (149), Expect = 5e-10, Method: Composition-based stats.
Identities = 32/95 (33%), Positives = 52/95 (54%), Gaps = 0/95 (0%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIR 62
Q AF GF + + +L P EL + +++ S+A L+ + GY+ DS I
Sbjct 1329 QLKAFIEGFSKVFSYERMLILFPDELVDIFGRVEEDWSMATLYTNLNAEHGYTMDSSIIH 1388
Query 63 RLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQAL 97
+I+S F ++R FL F+TGS +LP+GG ++L
Sbjct 1389 DFISIISAFGKHERRLFLQFLTGSPKLPIGGFKSL 1423
> ath:AT4G38600 KAK; KAK (KAKTUS); ubiquitin-protein ligase; K10590
E3 ubiquitin-protein ligase TRIP12 [EC:6.3.2.19]
Length=1794
Score = 62.0 bits (149), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 38/103 (36%), Positives = 53/103 (51%), Gaps = 5/103 (4%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIR 62
Q AF+ GF + D +L + P EL LL G ++ + L + ++ GY+ S AI
Sbjct 1633 QIEAFRSGFNQVFDITSLQIFTPSELDYLLCGRRELWEVETLAEHIKFDHGYNAKSPAI- 1691
Query 63 RLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQAL--RLTIGR 103
I+ T Q+R F FVTG+ RLP GG L +LTI R
Sbjct 1692 --INIMGELTADQQRAFCQFVTGAPRLPPGGLAVLNPKLTIVR 1732
> tpv:TP01_0229 ubiquitin-protein ligase
Length=4164
Score = 60.5 bits (145), Expect = 1e-09, Method: Composition-based stats.
Identities = 37/95 (38%), Positives = 52/95 (54%), Gaps = 2/95 (2%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIR 62
Q AF +GF + +S+ +EL+LL+ G I L + + Y + Y+EDSL I
Sbjct 4013 QLDAFMQGFRELIAPELISIFDDRELELLISGIPI-IDLENMKQNVEYIN-YTEDSLQII 4070
Query 63 RLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQAL 97
LW ILS F FL FVTG+ R+P+GG + L
Sbjct 4071 WLWEILSEFDQSHLAAFLQFVTGTSRVPIGGFKNL 4105
> dre:100073325 zgc:163136
Length=994
Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 32/101 (31%), Positives = 57/101 (56%), Gaps = 4/101 (3%)
Query 2 SQFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAI 61
+QF F GF + ++ P+ELQ LL GS Q + L ++ Y+ + D L I
Sbjct 847 TQFEQFTEGFSEGCPLDAWTMFHPEELQELLHGSPQ-YNWKELQQSASYEGCSASDEL-I 904
Query 62 RRLWAILSNFTDKQKRQFLMFVTGSDRLPVGG--AQALRLT 100
+ W + +++ K++FLMF+ G++R+P GG +AL+++
Sbjct 905 KNFWTVFFELSEENKKKFLMFLYGTERVPAGGFSKRALKIS 945
> cpv:cgd8_1200 E3A like HECT domain containing ubiquitin protein
ligase
Length=1561
Score = 59.3 bits (142), Expect = 3e-09, Method: Composition-based stats.
Identities = 39/101 (38%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIR 62
Q AF RG + + +L L P ELQ L+ G Q++ + L T Y GY+E S I
Sbjct 1414 QAEAFLRGLSTVIPNESLRLFSPYELQSLISGVYQKLDVNNLRLNTCYT-GYTETSQQII 1472
Query 63 RLWAILSN-FTDKQKRQFLMFVTGSDRLPVGGAQALRLTIG 102
LW IL N F+ +++ +FL+FVT S + P+ G Q L G
Sbjct 1473 WLWDILENEFSTEEQGEFLLFVTSSRKAPLLGFQHLNPKFG 1513
> hsa:79654 HECTD3, FLJ21156, FLJ31983, MGC161630, RP11-69J16.1;
HECT domain containing 3; K12233 E3 ubiquitin-protein ligase
HECTD3 [EC:6.3.2.19]
Length=861
Score = 59.3 bits (142), Expect = 3e-09, Method: Composition-based stats.
Identities = 33/88 (37%), Positives = 50/88 (56%), Gaps = 2/88 (2%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIR 62
Q AA + G + + L LL QEL+ + G E+++ L K TR++D DS ++
Sbjct 714 QVAAMQAGLLKVVPQAVLDLLTWQELEKKVCGDP-EVTVDALRKLTRFEDFEPSDS-RVQ 771
Query 63 RLWAILSNFTDKQKRQFLMFVTGSDRLP 90
W L+NFT++ + +FL FVTG RLP
Sbjct 772 YFWEALNNFTNEDRSRFLRFVTGRSRLP 799
> cel:Y39A1C.2 oxi-1; OXidative stress Induced family member (oxi-1);
K10588 ubiquitin-protein ligase E3 B [EC:6.3.2.19]
Length=1066
Score = 59.3 bits (142), Expect = 3e-09, Method: Composition-based stats.
Identities = 36/92 (39%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIR 62
Q AF G L LSL P +LQ L+ G +I LA L + +Y G+ + I+
Sbjct 893 QCKAFVTGMQSILQPTWLSLFAPNDLQCLISGVNSDIDLADLKRNVQYFGGFHGNHRLIK 952
Query 63 RLWAILSN-FTDKQKRQFLMFVTGSDRLPVGG 93
LW IL N FT ++++ FL FVT R PV G
Sbjct 953 WLWDILENKFTSEERKLFLKFVTSCSRPPVLG 984
> pfa:MAL8P1.23 ubiquitin-protein ligase 1, putative; K10592 E3
ubiquitin-protein ligase HUWE1 [EC:6.3.2.19]
Length=8591
Score = 58.9 bits (141), Expect = 4e-09, Method: Composition-based stats.
Identities = 34/95 (35%), Positives = 52/95 (54%), Gaps = 2/95 (2%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIR 62
Q AF GF + +S+ +EL+LL+ G I L L + Y + Y+ +S+ I
Sbjct 8440 QLEAFMDGFKELIQPKLISIFDDKELELLISGIPT-IDLNDLKENVEYHN-YTANSIQII 8497
Query 63 RLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQAL 97
LW +L F + +K FL FVTG+ R+P+GG + L
Sbjct 8498 WLWDVLQEFDENKKASFLQFVTGTSRVPLGGFKNL 8532
> cel:Y48G8AL.1 hypothetical protein
Length=1019
Score = 58.5 bits (140), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Query 1 ASQFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLA 60
A Q F++GF L S TL P EL+ +++G++ Y+ YS
Sbjct 874 AQQALLFRKGFSESLHSRTLRFFQPCELKEMIVGNEN-YDWNEFRDILMYRGEYSSSHPT 932
Query 61 IRRLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTI 101
I+ W TD ++R+FL F+TGS R+PV G + L I
Sbjct 933 IQAFWKAFFALTDDERRKFLQFLTGSTRIPVSGWEELHAAI 973
> hsa:4734 NEDD4, KIAA0093, MGC176705, NEDD4-1, RPF1; neural precursor
cell expressed, developmentally down-regulated 4 (EC:6.3.2.-);
K10591 E3 ubiquitin-protein ligase NEDD4 [EC:6.3.2.19]
Length=900
Score = 58.5 bits (140), Expect = 5e-09, Method: Composition-based stats.
Identities = 31/107 (28%), Positives = 56/107 (52%), Gaps = 1/107 (0%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIR 62
Q AAFK GFF + + + + EL+LL+ G ++ + + T+Y++GYS + I+
Sbjct 748 QMAAFKEGFFELIPQDLIKIFDENELELLMCG-LGDVDVNDWREHTKYKNGYSANHQVIQ 806
Query 63 RLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTIGRHGFDTD 109
W + +++ + L FVTG+ R+P+ G L + G F +
Sbjct 807 WFWKAVLMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVE 853
> mmu:76608 Hectd3, 1700064K09Rik, AI467540, AW743312; HECT domain
containing 3; K12233 E3 ubiquitin-protein ligase HECTD3
[EC:6.3.2.19]
Length=861
Score = 58.5 bits (140), Expect = 6e-09, Method: Composition-based stats.
Identities = 32/88 (36%), Positives = 50/88 (56%), Gaps = 2/88 (2%)
Query 3 QFAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIR 62
Q AA + G + + L LL QEL+ + G E+++ L K TR++D D+ ++
Sbjct 714 QVAAMQAGLLKVVPQAVLDLLTWQELEKKVCGDP-EVTVDALRKLTRFEDFEPSDT-RVQ 771
Query 63 RLWAILSNFTDKQKRQFLMFVTGSDRLP 90
W L+NFT++ + +FL FVTG RLP
Sbjct 772 YFWEALNNFTNEDRSRFLRFVTGRSRLP 799
> hsa:55008 HERC6, FLJ20637; hect domain and RLD 6
Length=986
Score = 58.5 bits (140), Expect = 6e-09, Method: Composition-based stats.
Identities = 27/96 (28%), Positives = 48/96 (50%), Gaps = 1/96 (1%)
Query 4 FAAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQEISLAVLHKATRYQDGYSEDSLAIRR 63
+ F+RGF+R + L P+EL ++G+ + + ++Y+ GY + I+
Sbjct 836 YEEFQRGFYRVCEKEILRHFYPEELMTAIIGNT-DYDWKQFEQNSKYEQGYQKSHPTIQL 894
Query 64 LWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRL 99
W T +K++FL F+TG DRL G Q + +
Sbjct 895 FWKAFHKLTLDEKKKFLFFLTGRDRLHARGIQKMEI 930
> sce:YJR036C HUL4; Hul4p (EC:6.3.2.-); K12232 E3 ubiquitin-protein
ligase HECTD2 [EC:6.3.2.19]
Length=892
Score = 58.2 bits (139), Expect = 6e-09, Method: Composition-based stats.
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 8/108 (7%)
Query 5 AAFKRGFFRCLDSNTLSLLLPQELQLLLLGSQQE--ISLAVLHKATRYQDGYSEDSLAIR 62
+ FKR F C N++ L +EL+ L+ G +++ L T+Y G+S+DS A+
Sbjct 748 SGFKRVFAEC---NSIKLFNSEELERLVCGDEEQTKFDFKSLRSVTKYVGGFSDDSRAVC 804
Query 63 RLWAILSNFTDKQKRQFLMFVTGSDRLPVGGAQALRLTI---GRHGFD 107
W I+ ++ +++ L FVT SDR+P G + I G H D
Sbjct 805 WFWEIIESWDYPLQKKLLQFVTASDRIPATGISTIPFKISLLGSHDSD 852
Lambda K H
0.325 0.139 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 2072286120
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
Posted date: Sep 17, 2011 11:19 AM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40