bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
164,496 sequences; 82,071,388 total letters
Query= Emax_0774_orf4
Length=231
Score E
Sequences producing significant alignments: (Bits) Value
xla:735106 ppap2a, MGC114881; phosphatidic acid phosphatase ty... 85.9 1e-16
cel:F13E6.5 hypothetical protein 83.2 7e-16
hsa:8613 PPAP2B, Dri42, LPP3, MGC15306, PAP2B, VCIP; phosphati... 82.4 1e-15
mmu:67916 Ppap2b, 1110003O22Rik, 2610002D05Rik, AV025606, D4Bw... 82.0 1e-15
xla:444206 MGC80748 protein; K01080 phosphatidate phosphatase ... 82.0 1e-15
dre:569053 hypothetical LOC569053 80.9 3e-15
tgo:TGME49_047360 lipid phosphate phosphohydrolase 3, putative... 79.7 8e-15
hsa:8611 PPAP2A, LLP1a, LPP1, PAP-2a, PAP2, PAP2a2, PAP2alpha2... 78.2 2e-14
xla:443763 ppap2c, MGC81169; phosphatidic acid phosphatase typ... 77.0 5e-14
dre:794598 Lipid phosphate phosphohydrolase 1-like; K01080 pho... 77.0 5e-14
mmu:19012 Ppap2a, Hic53, Hpic53, LPP-1, LPP1, mPAP; phosphatid... 75.1 2e-13
mmu:50784 Ppap2c, Lpp2; phosphatidic acid phosphatase type 2C ... 74.3 4e-13
dre:557680 ppap2b, si:dkey-19f4.1; phosphatidic acid phosphata... 70.9 3e-12
xla:447215 ppap2b-b, dri42, lpp3, pap2b, ppap2bb, vcip; phosph... 70.5 4e-12
cel:F53C3.13 hypothetical protein 69.7 8e-12
hsa:8612 PPAP2C, LPP2, PAP-2c, PAP2-g; phosphatidic acid phosp... 66.2 1e-10
dre:393428 MGC63577; zgc:63577 (EC:3.1.3.4) 65.5 2e-10
xla:447319 ppap2b-a, dri42, lpp3, pap2b, ppap2b, ppap2ba, vcip... 64.7 3e-10
hsa:54886 LPPR1, MGC26189, PRG-3; lipid phosphate phosphatase-... 64.3 4e-10
dre:415222 lppr1; zgc:86759 63.9 4e-10
cel:T28D9.3 hypothetical protein 63.5 6e-10
xla:444601 lppr5, MGC84075; lipid phosphate phosphatase-relate... 62.4 1e-09
mmu:272031 E130309F12Rik, KIAA4247, Lppr1, PRG-3, mKIAA4247; R... 62.0 2e-09
dre:571463 lipid phosphate phosphatase-related protein type 2-... 60.1 7e-09
mmu:75769 4833424O15Rik, Lppr5, PRG-5, Pap2d; RIKEN cDNA 48334... 58.9 1e-08
dre:100093705 zgc:165526 58.9 1e-08
hsa:163404 LPPR5, PAP2, PAP2D, PRG5; lipid phosphate phosphata... 58.2 3e-08
dre:559124 MGC158309, ppap2b; zgc:158309 (EC:3.1.3.4); K01080 ... 56.6 6e-08
dre:100006660 similar to phosphatidic acid phosphatase type 2d 55.1 2e-07
dre:100330890 lipid phosphate phosphatase-related protein type... 54.7 3e-07
hsa:64748 LPPR2, DKFZp761E1121, FLJ13055, PRG4; lipid phosphat... 53.1 7e-07
sce:YDR284C DPP1, ZRG1; Diacylglycerol pyrophosphate (DGPP) ph... 52.8 1e-06
dre:559888 si:dkey-108c13.1 52.4 1e-06
dre:335485 ppap2c, fj16e10, wu:fj16e10, zgc:66434; phosphatidi... 52.0 2e-06
mmu:229791 D3Bwg0562e, A330086D10, Lppr4, PRG-1, mKIAA0455; DN... 50.4 5e-06
dre:563806 Lipid phosphate phosphohydrolase 2-like; K01080 pho... 50.1 6e-06
mmu:235044 Lppr2, MGC25492, PRG-4; cDNA sequence BC018242 (EC:... 49.7 9e-06
hsa:9890 LPPR4, KIAA0455, LPR4, PHP1, PRG-1, PRG1, RP4-788L13.... 48.1 3e-05
xla:495974 ppapdc1a; phosphatidic acid phosphatase type 2 doma... 46.6 7e-05
dre:571722 brain-specific phosphatidic acid phosphatase-like p... 45.4 2e-04
ath:AT3G02600 LPP3; LPP3 (LIPID PHOSPHATE PHOSPHATASE 3); phos... 44.3 4e-04
dre:431758 ppapdc1b, fc49c04, wu:fc49c04, zgc:92365; phosphati... 43.5 7e-04
xla:443950 ppapdc1b, MGC80318; phosphatidic acid phosphatase t... 43.1 8e-04
mmu:216152 KIAA4076, Lppr3, Prg2; cDNA sequence BC005764 (EC:3... 42.4 0.001
hsa:84513 PPAPDC1B, DPPL1, HTPAP; phosphatidic acid phosphatas... 41.6 0.003
ath:AT2G01180 ATPAP1; ATPAP1 (PHOSPHATIDIC ACID PHOSPHATASE 1)... 41.2 0.003
hsa:196051 PPAPDC1A, DPPL2, MGC120299, MGC120300, PPAPDC1; pho... 40.4 0.005
mmu:71910 Ppapdc1b, 1810019D05Rik, 2310022A04Rik, AW045471, Pp... 40.0 0.007
hsa:79948 LPPR3, LPR3, PRG-2, PRG2; lipid phosphate phosphatas... 40.0 0.007
dre:100334794 phosphatidic acid phosphatase type 2C-like 39.7 0.008
> xla:735106 ppap2a, MGC114881; phosphatidic acid phosphatase
type 2A (EC:3.1.3.4); K01080 phosphatidate phosphatase [EC:3.1.3.4]
Length=283
Score = 85.9 bits (211), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 59/192 (30%), Positives = 89/192 (46%), Gaps = 20/192 (10%)
Query 40 FSLGRVIPSYPIRVLMHILSLLAVCLIAANSLTGTATVRGSFCNNTDIALPKKKGSINLG 99
F GR+ P +L + +LA A +L T RG FCN+ + P K+ +I+ G
Sbjct 2 FDKGRI----PFVILDIVCVILAGLPFAILNLKHTPFQRGFFCNDDSLWYPYKEDTISYG 57
Query 100 QLMVLSFVVPSIIIILVELLIALVRATEDKEAQQSSNVRMFCWEVPQWIVDLYTYLGGFG 159
L + I+IIL E L S++R + ++ +Y +G F
Sbjct 58 LLGGIMIPFCIIVIILGEALSVFY-----------SDLRSGAFIRNNYVATIYKAIGTFI 106
Query 160 FTMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMNDAHRVE 219
F A + D K +G LRPHF D CKP+W+++ C Y+E+F C D +
Sbjct 107 FGAAVSQSLTDIAKYTIGRLRPHFLDVCKPNWAKINCSLG-----YIENFVCEGDPTKSS 161
Query 220 DARRSFPSGHST 231
+ R SF SGHS+
Sbjct 162 EGRLSFYSGHSS 173
> cel:F13E6.5 hypothetical protein
Length=304
Score = 83.2 bits (204), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 52/155 (33%), Positives = 76/155 (49%), Gaps = 18/155 (11%)
Query 78 RGSFCNNTDIALPKKKGSINLGQLMVLSFVVPSIIIILVELLIALVRATEDKEAQQSSNV 137
R C + I P K+ ++ L L+V++ P +I+ LVE ++ ++ A+ S
Sbjct 66 RAMPCGDISIQQPFKENTVGLKHLLVITLGSPFLIVALVEAILHFKSKGSNRLAKFFSAT 125
Query 138 RMFCWEVPQWIVDLYTYLGGFGFTMATAWLFA-DSLKCFVGSLRPHFFDACKPDWSQVKC 196
+ TYL M A FA + LKC+VG LRPHFF CKPDWS+V C
Sbjct 126 TI-------------TYLKYL--LMYAACTFAMEFLKCYVGRLRPHFFSVCKPDWSKVDC 170
Query 197 KGSNGEYVYVEDFHCMN-DAHRVEDARRSFPSGHS 230
++ D C N + ++ AR SFPSGH+
Sbjct 171 TDKQS-FIDSSDLVCTNPNPRKIRTARTSFPSGHT 204
> hsa:8613 PPAP2B, Dri42, LPP3, MGC15306, PAP2B, VCIP; phosphatidic
acid phosphatase type 2B (EC:3.1.3.4); K01080 phosphatidate
phosphatase [EC:3.1.3.4]
Length=311
Score = 82.4 bits (202), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 62/188 (32%), Positives = 94/188 (50%), Gaps = 27/188 (14%)
Query 52 RVLMHILSLLAVCLIAANS---LTGTATV----RGSFCNNTDIALPKKKG-SINLGQLMV 103
RVL+ L L CL A + T+T+ RG +CN+ I P K G +IN L
Sbjct 33 RVLLICLDLF--CLFMAGLPFLIIETSTIKPYHRGFYCNDESIKYPLKTGETINDAVLCA 90
Query 104 LSFVVPSIIIILVELLIALVRATEDKEAQQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMA 163
+ V+ + II E R K+++ + + P ++ LY +G F F A
Sbjct 91 VGIVIAILAIITGEF----YRIYYLKKSRST-------IQNP-YVAALYKQVGCFLFGCA 138
Query 164 TAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMNDAHRVEDARR 223
+ F D K +G LRPHF C PD+SQ+ C S G Y++++ C D +V++AR+
Sbjct 139 ISQSFTDIAKVSIGRLRPHFLSVCNPDFSQINC--SEG---YIQNYRCRGDDSKVQEARK 193
Query 224 SFPSGHST 231
SF SGH++
Sbjct 194 SFFSGHAS 201
> mmu:67916 Ppap2b, 1110003O22Rik, 2610002D05Rik, AV025606, D4Bwg0538e,
D4Bwg1535e, Lpp3, Ppab2b; phosphatidic acid phosphatase
type 2B (EC:3.1.3.4); K01080 phosphatidate phosphatase
[EC:3.1.3.4]
Length=312
Score = 82.0 bits (201), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 61/186 (32%), Positives = 93/186 (50%), Gaps = 22/186 (11%)
Query 52 RVLMHILSLLAVCLIAANSLT-GTATV----RGSFCNNTDIALPKK-KGSINLGQLMVLS 105
RVL+ L L + + A L T+T+ RG +CN+ I P K +IN L +
Sbjct 33 RVLLICLDLFCLFMAALPFLIIETSTIKPYRRGFYCNDESIKYPLKVSETINDAVLCAVG 92
Query 106 FVVPSIIIILVELLIALVRATEDKEAQQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMATA 165
V+ + II E R KE +S+ + P ++ LY +G F F A +
Sbjct 93 IVIAILAIITGEF----YRIYYLKEKSRSTT------QNP-YVAALYKQVGCFLFGCAIS 141
Query 166 WLFADSLKCFVGSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMNDAHRVEDARRSF 225
F D K +G LRPHF C PD+SQ+ C S G Y++++ C + +V++AR+SF
Sbjct 142 QSFTDIAKVSIGRLRPHFLSVCDPDFSQINC--SEG---YIQNYRCRGEDSKVQEARKSF 196
Query 226 PSGHST 231
SGH++
Sbjct 197 FSGHAS 202
> xla:444206 MGC80748 protein; K01080 phosphatidate phosphatase
[EC:3.1.3.4]
Length=284
Score = 82.0 bits (201), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 54/176 (30%), Positives = 79/176 (44%), Gaps = 23/176 (13%)
Query 63 VCLIAA-------NSLTGTATVRGSFCNNTDIALPKKKGSINLGQLMVLSFVVPSIIIIL 115
VCLI A +T RG FC++ I P ++ L + F VP +IL
Sbjct 15 VCLILAALPLGVLKLITKKPYQRGFFCDDDSIKYPFHDSTVTSTVLYTVGFTVPICSMIL 74
Query 116 VELLIALVRATEDKEAQQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCF 175
E L + + + S+ +R ++ +Y +G F F A + D K
Sbjct 75 GETLSVVY-----NDLRSSAFIR------NNYVATIYKAIGTFIFGAAASQSLTDIAKYT 123
Query 176 VGSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMNDAHRVEDARRSFPSGHST 231
+G LRPHF D CKP+WS++ C Y+E F C D + + R SF SGHS+
Sbjct 124 IGRLRPHFLDVCKPNWSKINCSLG-----YIETFVCEGDPTKSSEGRLSFYSGHSS 174
> dre:569053 hypothetical LOC569053
Length=303
Score = 80.9 bits (198), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 50/154 (32%), Positives = 71/154 (46%), Gaps = 16/154 (10%)
Query 78 RGSFCNNTDIALPKKKGSINLGQLMVLSFVVPSIIIILVELLIALVRATEDKEAQQSSNV 137
RG FCN+ I P K+ +I+ L + V + +I+ E L + +
Sbjct 58 RGFFCNDDSIKYPYKEDTISYQLLGGVMIPVTLLTMIIGECLSVYLNRIKSNS------- 110
Query 138 RMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCK 197
FC ++ +Y +G F F A + D K +G LRPHF D CKPDWS++ C
Sbjct 111 --FC---NGYVACVYKAIGTFVFGAAISQSLTDIAKYSIGRLRPHFLDVCKPDWSKINCT 165
Query 198 GSNGEYVYVEDFHCMNDAHRVEDARRSFPSGHST 231
Y+EDF C V + R SF SGHS+
Sbjct 166 AG----AYIEDFVCTGKESVVNEGRLSFYSGHSS 195
> tgo:TGME49_047360 lipid phosphate phosphohydrolase 3, putative
(EC:3.1.3.4); K01080 phosphatidate phosphatase [EC:3.1.3.4]
Length=320
Score = 79.7 bits (195), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 37/89 (41%), Positives = 55/89 (61%), Gaps = 3/89 (3%)
Query 145 PQWIVDLYTY-LGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCKGSNGEY 203
P +V LY GGF F + + + + K VG LRPHF C+PDWS++ C +NG +
Sbjct 117 PSGVVALYYQSFGGFAFALLSCYAITLTAKICVGRLRPHFLSVCQPDWSRIACSDANG-F 175
Query 204 VYVEDFHCM-NDAHRVEDARRSFPSGHST 231
+Y++ F C+ D +++AR SFPSGHS+
Sbjct 176 LYIDKFECLGTDKAAIKEARVSFPSGHSS 204
> hsa:8611 PPAP2A, LLP1a, LPP1, PAP-2a, PAP2, PAP2a2, PAP2alpha2,
PAPalpha1; phosphatidic acid phosphatase type 2A (EC:3.1.3.4);
K01080 phosphatidate phosphatase [EC:3.1.3.4]
Length=284
Score = 78.2 bits (191), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 60/186 (32%), Positives = 88/186 (47%), Gaps = 19/186 (10%)
Query 46 IPSYPIRVLMHILSLLAVCLIAANSLTGTATVRGSFCNNTDIALPKKKGSINLGQLMVLS 105
+P + VL +L+ L ++ + T RG FCN+ I P K+ +I L +
Sbjct 7 LPYVALDVLCVLLAGLPFAILTSRH---TPFQRGVFCNDESIKYPYKEDTIPYALLGGII 63
Query 106 FVVPSIIIILVELLIALVRATEDKEAQQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMATA 165
I+IIL E L +S +R +I +Y +G F F A +
Sbjct 64 IPFSIIVIILGETLSVYCNLL-----HSNSFIR------NNYIATIYKAIGTFLFGAAAS 112
Query 166 WLFADSLKCFVGSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMNDAHRVEDARRSF 225
D K +G LRPHF D C PDWS++ C S+G Y+E + C +A RV++ R SF
Sbjct 113 QSLTDIAKYSIGRLRPHFLDVCDPDWSKINC--SDG---YIEYYICRGNAERVKEGRLSF 167
Query 226 PSGHST 231
SGHS+
Sbjct 168 YSGHSS 173
> xla:443763 ppap2c, MGC81169; phosphatidic acid phosphatase type
2C (EC:3.1.3.4); K01080 phosphatidate phosphatase [EC:3.1.3.4]
Length=257
Score = 77.0 bits (188), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 48/162 (29%), Positives = 70/162 (43%), Gaps = 18/162 (11%)
Query 70 SLTGTATVRGSFCNNTDIALPKKKGSINLGQLMVLSFVVPSIIIILVELLIALVRATEDK 129
SL + RG +CN+ I P ++ +I G + ++ III E+ + + +
Sbjct 2 SLVNSPYKRGFYCNDESIRYPYREDTITNGLMATVTISCTVIIISSGEMYMVFSKRLYSR 61
Query 130 EAQQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKP 189
E +I LY +G + F A + D K +G RP+F C P
Sbjct 62 S------------ECNNYIAALYKVVGTYLFGAAVSQSLTDLAKYMIGRPRPNFLAVCDP 109
Query 190 DWSQVKCKGSNGEYVYVEDFHCMNDAHRVEDARRSFPSGHST 231
DWS V C YV DF C + V D+R SF SGHS+
Sbjct 110 DWSTVNCSR------YVTDFTCRGNYANVTDSRLSFYSGHSS 145
> dre:794598 Lipid phosphate phosphohydrolase 1-like; K01080 phosphatidate
phosphatase [EC:3.1.3.4]
Length=293
Score = 77.0 bits (188), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 47/154 (30%), Positives = 71/154 (46%), Gaps = 19/154 (12%)
Query 78 RGSFCNNTDIALPKKKGSINLGQLMVLSFVVPSIIIILVELLIALVRATEDKEAQQSSNV 137
RG FC++ I P K+ +I+ LM + + ++I+ E +R+
Sbjct 51 RGFFCSDDSIRYPFKEDTISYQLLMGIMIPLALLLIVFGECFSIYLRSRAS--------- 101
Query 138 RMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCK 197
F +E ++ +Y +G F F A + D K +G LRPHF CKP WS + CK
Sbjct 102 --FSYE---YVACVYKAVGSFVFGAAVSQSLTDIAKYTIGRLRPHFLTVCKPHWSLIDCK 156
Query 198 GSNGEYVYVEDFHCMNDAHRVEDARRSFPSGHST 231
Y+E+F C D + R SF SGHS+
Sbjct 157 AG-----YIENFTCTGDPTLTNEGRLSFYSGHSS 185
> mmu:19012 Ppap2a, Hic53, Hpic53, LPP-1, LPP1, mPAP; phosphatidic
acid phosphatase type 2A (EC:3.1.3.4); K01080 phosphatidate
phosphatase [EC:3.1.3.4]
Length=284
Score = 75.1 bits (183), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 45/154 (29%), Positives = 70/154 (45%), Gaps = 16/154 (10%)
Query 78 RGSFCNNTDIALPKKKGSINLGQLMVLSFVVPSIIIILVELLIALVRATEDKEAQQSSNV 137
RG FC + + P +I L +L +P + + E L +
Sbjct 37 RGFFCTDNSVKYPYHDSTIPSRILAILGLGLPIFSMSIGESLSVYFNVLHSNSFVGNP-- 94
Query 138 RMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCK 197
+I +Y +G F F ++ + D K +GSLRPHF C PDWS++ C
Sbjct 95 ---------YIATIYKAVGAFLFGVSASQSLTDIAKYTIGSLRPHFLAICNPDWSKINC- 144
Query 198 GSNGEYVYVEDFHCMNDAHRVEDARRSFPSGHST 231
S+G Y+ED+ C + +V++ R SF SGHS+
Sbjct 145 -SDG---YIEDYICQGNEEKVKEGRLSFYSGHSS 174
> mmu:50784 Ppap2c, Lpp2; phosphatidic acid phosphatase type 2C
(EC:3.1.3.4); K01080 phosphatidate phosphatase [EC:3.1.3.4]
Length=276
Score = 74.3 bits (181), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 50/162 (30%), Positives = 74/162 (45%), Gaps = 18/162 (11%)
Query 70 SLTGTATVRGSFCNNTDIALPKKKGSINLGQLMVLSFVVPSIIIILVELLIALVRATEDK 129
+L RG +C + I P + +I G +++ V+ + +ILV L A + T+
Sbjct 26 TLVNAPYKRGFYCGDDSIRYPYRPDTITHG---LMAGVIITATVILVSLGEAYLVYTDRL 82
Query 130 EAQQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKP 189
++ + N ++ +Y LG F F A + D K +G LRP F C P
Sbjct 83 YSRSNFN---------NYVAAIYKVLGTFLFGAAVSQSLTDLAKYMIGRLRPSFLAVCDP 133
Query 190 DWSQVKCKGSNGEYVYVEDFHCMNDAHRVEDARRSFPSGHST 231
DWSQV C G YV+ C V +AR SF SGHS+
Sbjct 134 DWSQVNCSG------YVQLEVCRGSPANVTEARLSFYSGHSS 169
> dre:557680 ppap2b, si:dkey-19f4.1; phosphatidic acid phosphatase
type 2B; K01080 phosphatidate phosphatase [EC:3.1.3.4]
Length=312
Score = 70.9 bits (172), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 46/175 (26%), Positives = 82/175 (46%), Gaps = 17/175 (9%)
Query 57 ILSLLAVCLIAANSLTGTATVRGSFCNNTDIALPKKKGSINLGQLMVLSFVVPSIIIILV 116
+L++L +I +++ RG +C++ I P K G ++ + I+I++
Sbjct 44 VLAVLPFLIIETSTIKPYH--RGFYCSDQSIQYPYKNGDTISDAVLCAA----GILIVIF 97
Query 117 ELLIALVRATEDKEAQQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFV 176
++I S V ++ LY +G F F A + F D K V
Sbjct 98 SIVIGECYRIHYLSQGSKSFVGN------PYVSALYRQVGVFIFGCAVSQSFTDIAKVSV 151
Query 177 GSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMNDAHRVEDARRSFPSGHST 231
G +RPHF D C+P++S + C Y+ ++ C D +V++AR+SF SGH++
Sbjct 152 GRMRPHFLDVCRPNYSTIDCSLG-----YITEYTCTGDPSKVQEARKSFFSGHAS 201
> xla:447215 ppap2b-b, dri42, lpp3, pap2b, ppap2bb, vcip; phosphatidic
acid phosphatase type 2B (EC:3.1.3.4); K01080 phosphatidate
phosphatase [EC:3.1.3.4]
Length=307
Score = 70.5 bits (171), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 53/188 (28%), Positives = 88/188 (46%), Gaps = 26/188 (13%)
Query 52 RVLMHILSLLAVCLIAANS---LTGTATV----RGSFCNNTDIALPKKKG-SINLGQLMV 103
+VL+ L + CL+ A + T+T+ RG +C + I P G +I+ L
Sbjct 33 KVLLIFLDVF--CLVVAGLPFLIIETSTIQPYHRGFYCGDESIKYPANSGETISDAVLSA 90
Query 104 LSFVVPSIIIILVELLIALVRATEDKEAQQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMA 163
+ + + II+ E R KE +S + ++ LY +G F F +
Sbjct 91 VGIFIAILAIIVGEFF----RIHYLKERPRS-------FIQNPYVAALYKQVGCFAFGCS 139
Query 164 TAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMNDAHRVEDARR 223
+ F D K +G LRPHF + C PD+S + C Y+E++ C ++V +AR+
Sbjct 140 VSQSFTDIAKVAIGRLRPHFLNVCDPDFSTINCSLG-----YIENYVCRGPPNKVMEARK 194
Query 224 SFPSGHST 231
SF SGH++
Sbjct 195 SFFSGHAS 202
> cel:F53C3.13 hypothetical protein
Length=385
Score = 69.7 bits (169), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 49/175 (28%), Positives = 85/175 (48%), Gaps = 7/175 (4%)
Query 57 ILSLLAVCLIAANSLTGTATVRGSFCNNTDIALPKKKGSINLGQLMVLSFVVPSIIIILV 116
+L+L+A+ L + RG +C++ I P + + L+V+ ++P ++I+
Sbjct 18 VLTLIAIPLYVFHEFIPPVR-RGFYCDDESIRYPFRDSKVTRQMLIVVGLLIPILLILAT 76
Query 117 ELLIALVRATEDKEAQQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFV 176
EL L + + ++ +VR V + +V LY ++G F + L D K +
Sbjct 77 ELFRTLAWEKKCETEFKTYHVRNH--SVHRLVVRLYCFIGYFFVGVCFNQLMVDIAKYTI 134
Query 177 GSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHC-MNDAHRVEDARRSFPSGHS 230
G RPHF D C+PD C + +Y+ DF C D ++ +A+ SF SGHS
Sbjct 135 GRQRPHFMDVCRPDIGYQTCSQPD---LYITDFKCTTTDTKKIHEAQLSFYSGHS 186
> hsa:8612 PPAP2C, LPP2, PAP-2c, PAP2-g; phosphatidic acid phosphatase
type 2C (EC:3.1.3.4); K01080 phosphatidate phosphatase
[EC:3.1.3.4]
Length=288
Score = 66.2 bits (160), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 48/162 (29%), Positives = 73/162 (45%), Gaps = 17/162 (10%)
Query 70 SLTGTATVRGSFCNNTDIALPKKKGSINLGQLMVLSFVVPSIIIILVELLIALVRATEDK 129
+L RG +C + I P + +I G +++ V + +ILV A + T+
Sbjct 26 TLVNAPYKRGFYCGDDSIRYPYRPDTITHG---LMAGVTITATVILVSAGEAYLVYTDRL 82
Query 130 EAQQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKP 189
++ N ++ +Y LG F F A + D K +G LRP+F C P
Sbjct 83 YSRSDFN---------NYVAAVYKVLGTFLFGAAVSQSLTDLAKYMIGRLRPNFLAVCDP 133
Query 190 DWSQVKCKGSNGEYVYVEDFHCMNDAHRVEDARRSFPSGHST 231
DWS+V C YV +E C + V +AR SF SGHS+
Sbjct 134 DWSRVNC----SVYVQLEKV-CRGNPADVTEARLSFYSGHSS 170
> dre:393428 MGC63577; zgc:63577 (EC:3.1.3.4)
Length=360
Score = 65.5 bits (158), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 42/155 (27%), Positives = 80/155 (51%), Gaps = 9/155 (5%)
Query 77 VRGSFCNNTDIA--LPKKKGSINLGQLMVLSFV--VPSIIIILVELLIALVRATEDKEAQ 132
++G FC + + P + N+ ++V S + +P+I I+ E+++ +RA + Q
Sbjct 60 IQGFFCFDKAFSKPYPGPDETSNVPPVLVYSLIAAIPTITILAGEVMVFFMRA---EGTQ 116
Query 133 QSSNVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDWS 192
+ + V C + + +LG + F + T +FA++ + G+ PHF AC+P+++
Sbjct 117 EKTIVTADCCYFNPLLRRIIRFLGVYTFGVFTTTIFANAGQVVTGNQTPHFLSACRPNYT 176
Query 193 QVKCKGSNGEYVYVEDFHCMNDAHRVEDARRSFPS 227
+ C SN +Y+ E C + V AR+SFPS
Sbjct 177 ALGCH-SNLQYI-TERKACTGNPLIVASARKSFPS 209
> xla:447319 ppap2b-a, dri42, lpp3, pap2b, ppap2b, ppap2ba, vcip;
phosphatidic acid phosphatase type 2B (EC:3.1.3.4); K01080
phosphatidate phosphatase [EC:3.1.3.4]
Length=307
Score = 64.7 bits (156), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 55/188 (29%), Positives = 88/188 (46%), Gaps = 26/188 (13%)
Query 52 RVLMHILSLLAVCLIAANS---LTGTATV----RGSFCNNTDIALPKKKG-SINLGQLMV 103
RVL+ +L + CLI A + T+T+ RG +C + I P G +I+ L
Sbjct 33 RVLLILLDVF--CLIVAGLPFLIIETSTIQPYRRGFYCGDESIKYPANTGETISDAVLSA 90
Query 104 LSFVVPSIIIILVELLIALVRATEDKEAQQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMA 163
+ ++ + II+ E R KE S + ++ LY +G F F +
Sbjct 91 VGILIAILAIIVGEFF----RIHYLKERPHS-------FIQNPYVAALYKQVGCFVFGCS 139
Query 164 TAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMNDAHRVEDARR 223
+ F D K +G LRPHF C PD+S + C Y+E++ C ++V +AR+
Sbjct 140 VSQSFTDIAKVAIGRLRPHFLKVCDPDFSIIDCSLG-----YIENYECRGPPNKVMEARK 194
Query 224 SFPSGHST 231
SF SGH++
Sbjct 195 SFFSGHAS 202
> hsa:54886 LPPR1, MGC26189, PRG-3; lipid phosphate phosphatase-related
protein type 1
Length=325
Score = 64.3 bits (155), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 39/160 (24%), Positives = 78/160 (48%), Gaps = 9/160 (5%)
Query 77 VRGSFCNNTDIALP----KKKGSINLGQLMVLSFVVPSIIIILVELLIALVRAT-EDKEA 131
++G FC + D+ P +++ I L + P+ II + E+ + +++T E A
Sbjct 45 IQGFFCQDGDLMKPYPGTEEESFITPLVLYCVLAATPTAIIFIGEISMYFIKSTRESLIA 104
Query 132 QQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDW 191
Q+ + + C + + + + G F F + +F ++ + G L P+F CKP++
Sbjct 105 QEKTILTGECCYLNPLLRRIIRFTGVFAFGLFATDIFVNAGQVVTGHLTPYFLTVCKPNY 164
Query 192 SQVKCKGSNGEYVYVEDFH-CMNDAHRVEDARRSFPSGHS 230
+ C+ + ++ + + C D +E ARRSFPS H+
Sbjct 165 TSADCQ---AHHQFINNGNICTGDLEVIEKARRSFPSKHA 201
> dre:415222 lppr1; zgc:86759
Length=333
Score = 63.9 bits (154), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 44/156 (28%), Positives = 83/156 (53%), Gaps = 7/156 (4%)
Query 77 VRGSFCNNTDIALPKK-KGSINLGQLMVLSFVV---PSIIIILVELLIALVRAT-EDKEA 131
++G FCN+ D+ P + Q ++L VV P+ II + E+ + ++++T E A
Sbjct 44 IQGFFCNDADLLKPYPGPEESSFIQPLILYCVVAAAPTAIIFVGEISMYIMKSTGEALLA 103
Query 132 QQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDW 191
Q+ + V C + I + ++G F F + +F ++ + G+L P+F + CKP++
Sbjct 104 QEKTIVTGECCYLNPLIRRIIRFIGVFAFGLFATDIFVNAGQVVTGNLAPYFLNVCKPNY 163
Query 192 SQVKCKGSNGEYVYVEDFHCMNDAHRVEDARRSFPS 227
+ + C S+ +++ + C + VE ARRSFPS
Sbjct 164 TGLDCHFSH-QFIANGNI-CTGNQVVVERARRSFPS 197
> cel:T28D9.3 hypothetical protein
Length=358
Score = 63.5 bits (153), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 48/158 (30%), Positives = 71/158 (44%), Gaps = 17/158 (10%)
Query 78 RGSFCNNTDIALPKKKGSINLGQLMVLSFVVPSIIIILVELLIALVRATEDKEAQQSSNV 137
RG FC++ I +K +I QLM+ + V+ + ++ VE ++ + + N
Sbjct 70 RGFFCDDDSIRYEYRKDTITAVQLMLYNLVLNAATVLFVEYY-------RMQKVESNINN 122
Query 138 RMFCW---EVPQWIVDLYTYLG--GFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDWS 192
+ W + V L TY G GF M A K VG LRPHF D CK +
Sbjct 123 PRYRWRNNHLHVLFVRLLTYFGYSQIGFVMNIALNIVT--KHVVGRLRPHFLDVCK--LA 178
Query 193 QVKCKGSNGEYVYVEDFHCMNDAHRVEDARRSFPSGHS 230
C + + Y+ D+ C V +AR+SF SGHS
Sbjct 179 NDTCVTGDS-HRYITDYTCTGPPELVLEARKSFYSGHS 215
> xla:444601 lppr5, MGC84075; lipid phosphate phosphatase-related
protein type 5
Length=305
Score = 62.4 bits (150), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 45/162 (27%), Positives = 80/162 (49%), Gaps = 9/162 (5%)
Query 72 TGTATVRGSFCNNTDIA--LPKKKGSINLGQLMVLSFV--VPSIIIILVELLI-ALVRAT 126
T T V+G FC ++ P S ++ +++LS V VP ++II+ E ++ L AT
Sbjct 24 TFTVNVQGFFCYDSSYTKPYPGPDESSDIPPVLLLSLVTGVPVLVIIVGETVVFCLQVAT 83
Query 127 EDKEAQQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDA 186
D E Q+ + + C + + +LG + F + +F ++ + G+L PHF
Sbjct 84 RDFENQEKTLLTGDCCYINPLVRRTVRFLGIYTFGLFATDIFVNAGQVVTGNLAPHFLTV 143
Query 187 CKPDWSQVKCKGSNGEYVYVEDFH-CMNDAHRVEDARRSFPS 227
CKP+++ + C+ ++ D + C V ARR+FPS
Sbjct 144 CKPNYTALGCRQFTQ---FITDANACTGIPDLVIKARRTFPS 182
> mmu:272031 E130309F12Rik, KIAA4247, Lppr1, PRG-3, mKIAA4247;
RIKEN cDNA E130309F12 gene
Length=325
Score = 62.0 bits (149), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 37/159 (23%), Positives = 80/159 (50%), Gaps = 7/159 (4%)
Query 77 VRGSFCNNTDIALP----KKKGSINLGQLMVLSFVVPSIIIILVELLIALVRAT-EDKEA 131
++G FC + D+ P +++ I+ L + P+ II + E+ + +++T E A
Sbjct 45 IQGFFCQDGDLMKPYPGTEEESFISPLVLYCVLAATPTAIIFIGEISMYFIKSTRESLIA 104
Query 132 QQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDW 191
++ + C + + + ++G F F + +F ++ + G L P+F C+P++
Sbjct 105 EEKMILTGDCCYLSPLLRRIIRFIGVFAFGLFATDIFVNAGQVVTGHLTPYFLTVCQPNY 164
Query 192 SQVKCKGSNGEYVYVEDFHCMNDAHRVEDARRSFPSGHS 230
+ C+ ++ +++ + C D +E ARRSFPS H+
Sbjct 165 TSTDCR-AHQQFINNGNI-CTGDLEVIEKARRSFPSKHA 201
> dre:571463 lipid phosphate phosphatase-related protein type
2-like
Length=336
Score = 60.1 bits (144), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 40/158 (25%), Positives = 77/158 (48%), Gaps = 9/158 (5%)
Query 77 VRGSFCNNTDIA--LPKKKGSINLGQLMVLSFV--VPSIIIILVELLIALVRATEDKEAQ 132
++G FC + + P + ++V S V +P++ I+L EL T+ + +Q
Sbjct 29 IQGFFCYDKTFSKPYPGPEDDSKAPPVLVYSLVTAIPTVTILLGELASFF---TKPEASQ 85
Query 133 QSSNVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDWS 192
+ + V C + + +LG + F + T +FA++ + G+ PHF C+P+++
Sbjct 86 EKTIVTADCCYFNPLLRRIVRFLGVYSFGLFTTTIFANAGQVVTGNQTPHFLSTCRPNYT 145
Query 193 QVKCKGSNGEYVYVEDFHCMNDAHRVEDARRSFPSGHS 230
+ C S +Y+ E C + + + AR+SFPS S
Sbjct 146 ALGCH-SPMQYI-TERRACTGNPYLIASARKSFPSKDS 181
> mmu:75769 4833424O15Rik, Lppr5, PRG-5, Pap2d; RIKEN cDNA 4833424O15
gene
Length=316
Score = 58.9 bits (141), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 41/164 (25%), Positives = 80/164 (48%), Gaps = 7/164 (4%)
Query 72 TGTATVRGSFCNNTDIALP----KKKGSINLGQLMVLSFVVPSIIIILVELLI-ALVRAT 126
T T V+G FC+++ P + ++ L L+ VP ++II+ E + L AT
Sbjct 35 TFTVNVQGFFCHDSAYRKPYPGPEDSSAVPPVLLYSLAAGVPVLVIIVGETAVFCLQLAT 94
Query 127 EDKEAQQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDA 186
D E Q+ + + C + + +LG + F + +F ++ + G+L PHF
Sbjct 95 RDFENQEKTILTGDCCYINPLVRRTVRFLGIYAFGLFATDIFVNAGQVVTGNLAPHFLAL 154
Query 187 CKPDWSQVKCKGSNGEYVYVEDFHCMNDAHRVEDARRSFPSGHS 230
CKP+++ + C+ +++ E+ C + + AR++FPS +
Sbjct 155 CKPNYTALGCQQYT-QFISGEE-ACTGNPDLIMRARKTFPSKEA 196
> dre:100093705 zgc:165526
Length=301
Score = 58.9 bits (141), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 38/156 (24%), Positives = 80/156 (51%), Gaps = 7/156 (4%)
Query 77 VRGSFCNNTDIALP----KKKGSINLGQLMVLSFVVPSIIIILVELLIALVRAT-EDKEA 131
V+G FC T P + +I L + VP+++I + E ++ L++ T +D ++
Sbjct 21 VQGFFCYETAYTKPYLGPEDTSAIPPALLYAVVTGVPTLMITVTETVLFLIQYTSKDLDS 80
Query 132 QQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDW 191
++ + V C + + + +LG + F + T +F ++ + G+L PHF CKP++
Sbjct 81 REKTMVTGDCCYLNPLVRRTFRFLGVYLFGLFTTDIFVNAGQVVTGNLAPHFLTVCKPNF 140
Query 192 SQVKCKGSNGEYVYVEDFHCMNDAHRVEDARRSFPS 227
+ + C+ + Y+ ++ C + + AR++FPS
Sbjct 141 TALGCQQA-LRYISHQE-ACTGNEDDILRARKTFPS 174
> hsa:163404 LPPR5, PAP2, PAP2D, PRG5; lipid phosphate phosphatase-related
protein type 5
Length=316
Score = 58.2 bits (139), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 41/164 (25%), Positives = 80/164 (48%), Gaps = 7/164 (4%)
Query 72 TGTATVRGSFCNNTDIALP----KKKGSINLGQLMVLSFVVPSIIIILVELLI-ALVRAT 126
T T V+G FC+++ P + ++ L L+ VP ++II+ E + L AT
Sbjct 35 TFTVNVQGFFCHDSAYRKPYPGPEDSSAVPPVLLYSLAAGVPVLVIIVGETAVFCLQLAT 94
Query 127 EDKEAQQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDA 186
D E Q+ + + C + + +LG + F + +F ++ + G+L PHF
Sbjct 95 RDFENQEKTILTGDCCYINPLVRRTVRFLGIYTFGLFATDIFVNAGQVVTGNLAPHFLAL 154
Query 187 CKPDWSQVKCKGSNGEYVYVEDFHCMNDAHRVEDARRSFPSGHS 230
CKP+++ + C+ +++ E+ C + + AR++FPS +
Sbjct 155 CKPNYTALGCQQYT-QFISGEE-ACTGNPDLIMRARKTFPSKEA 196
> dre:559124 MGC158309, ppap2b; zgc:158309 (EC:3.1.3.4); K01080
phosphatidate phosphatase [EC:3.1.3.4]
Length=323
Score = 56.6 bits (135), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 41/158 (25%), Positives = 64/158 (40%), Gaps = 14/158 (8%)
Query 74 TATVRGSFCNNTDIALPKKKGSINLGQLMVLSFVVPSIIIILVELLIALVRATEDKEAQQ 133
T +RG FC +T I P + +++ III + + + ++
Sbjct 78 TPYMRGFFCGDTSITYPYIESEAIPDSVLIAG----GIIITGLTIAVGECYRVRFRDVHS 133
Query 134 SSNVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDWSQ 193
+ VR ++ LY LG F F + K VG LRPHF AC +
Sbjct 134 RAFVRNL------YVSCLYKELGSFLFGCCVGQSLTNMAKLSVGRLRPHFLSACNVTYES 187
Query 194 VKCKGSNGEYVYVEDFHCMNDAHRVEDARRSFPSGHST 231
+ C Y+ C + VE+AR+SF SGH++
Sbjct 188 LNCTPGT----YISHVVCKSSKKIVEEARKSFFSGHAS 221
> dre:100006660 similar to phosphatidic acid phosphatase type
2d
Length=309
Score = 55.1 bits (131), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 38/164 (23%), Positives = 78/164 (47%), Gaps = 7/164 (4%)
Query 72 TGTATVRGSFCNNTDIALP----KKKGSINLGQLMVLSFVVPSIIIILVE-LLIALVRAT 126
T V+G FC++ P ++ +I L + VP+++I + E +L L +
Sbjct 24 TFNVHVQGFFCHDNAYTKPYLGPEESSAIPPAILYAVVAGVPALVITVTESVLFLLQYVS 83
Query 127 EDKEAQQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDA 186
ED + ++ V C + + + +LG + F + +F ++ + G+L P+F
Sbjct 84 EDLDNREKIIVMGDCCYLNPLVRRTFRFLGVYAFGLFATDIFVNAGQVVTGNLSPYFLTV 143
Query 187 CKPDWSQVKCKGSNGEYVYVEDFHCMNDAHRVEDARRSFPSGHS 230
CKP+++ + C+ ++ +D C + + AR+SFPS +
Sbjct 144 CKPNYTALGCQ-QVVRFINQQD-ACTGNEDDILHARKSFPSKEA 185
> dre:100330890 lipid phosphate phosphatase-related protein type
2-like
Length=299
Score = 54.7 bits (130), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 33/115 (28%), Positives = 60/115 (52%), Gaps = 5/115 (4%)
Query 113 IILVELLIALVRATEDKEAQQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSL 172
I+ E+++ +RA + Q+ + V C + + +LG + F + T +FA++
Sbjct 39 ILAGEVMVFFMRA---EGTQEKTIVTADCCYFNPLLRRIIRFLGVYTFGVFTTTIFANAG 95
Query 173 KCFVGSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMNDAHRVEDARRSFPS 227
+ G+ PHF AC+P+++ + C SN +Y+ E C + V AR+SFPS
Sbjct 96 QVVTGNQTPHFLSACRPNYTALGCH-SNLQYI-TERKACTGNPLIVASARKSFPS 148
> hsa:64748 LPPR2, DKFZp761E1121, FLJ13055, PRG4; lipid phosphate
phosphatase-related protein type 2 (EC:3.1.3.4)
Length=427
Score = 53.1 bits (126), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 40/161 (24%), Positives = 70/161 (43%), Gaps = 11/161 (6%)
Query 77 VRGSFCNNTDIA--LPKKKGSINLGQLMVLSFVV--PSIIIILVELLIALVRATEDKEA- 131
V G FC ++ A P + + + +V + V P++ I+L EL A A
Sbjct 21 VEGFFCYDSTYAKPYPGPEAASRVPPALVYALVTAGPTLTILLGELARAFFPAPPSAVPV 80
Query 132 -QQSSNVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPD 190
+S+ V C + L +LG + F + T +FA++ + G+ PHF C+P+
Sbjct 81 IGESTIVSGACCRFSPPVRRLVRFLGVYSFGLFTTTIFANAGQVVTGNPTPHFLSVCRPN 140
Query 191 WSQVKCKGSNGEYVYVEDF-----HCMNDAHRVEDARRSFP 226
++ + C + + + F C V ARR+FP
Sbjct 141 YTALGCLPPSPDRPGPDRFVTDQGACAGSPSLVAAARRAFP 181
> sce:YDR284C DPP1, ZRG1; Diacylglycerol pyrophosphate (DGPP)
phosphatase, zinc-regulated vacuolar membrane-associated lipid
phosphatase, dephosphorylates DGPP to phosphatidate (PA)
and Pi, then PA to diacylglycerol; involved in lipid signaling
and cell metabolism (EC:3.1.3.4 3.1.3.-)
Length=289
Score = 52.8 bits (125), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 43/156 (27%), Positives = 66/156 (42%), Gaps = 29/156 (18%)
Query 78 RGSFCNNTDIALPKKKGS-INLGQLMVLSFVVPSIIIILVELLIALVRATEDKEAQQSSN 136
R + N+ I+ P +N L V SFVVPS+ I+++ ++A R
Sbjct 43 RQFYINDLTISHPYATTERVNNNMLFVYSFVVPSLTILIIGSILADRR------------ 90
Query 137 VRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVKC 196
I LYT L G + F + +K ++G LRP F D C+P
Sbjct 91 ---------HLIFILYTSLLGLSLAWFSTSFFTNFIKNWIGRLRPDFLDRCQP------V 135
Query 197 KGSNGEYVYVEDFHCMNDAH-RVEDARRSFPSGHST 231
+G + ++ C H R+ D R+ PSGHS+
Sbjct 136 EGLPLDTLFTAKDVCTTKNHERLLDGFRTTPSGHSS 171
> dre:559888 si:dkey-108c13.1
Length=775
Score = 52.4 bits (124), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 35/156 (22%), Positives = 67/156 (42%), Gaps = 4/156 (2%)
Query 79 GSFCNNTDIALP---KKKGSINLGQLMVLSFVVPSIIIILVELLIALVRATEDKEAQQSS 135
G CN+ +++P K I L L+F P++ I++ E ++ A + + +
Sbjct 52 GYSCNDRSLSMPYIEPTKEVIPFLMLFSLAFAGPAVTIMIGEGILYCCVARRNIAIKTEA 111
Query 136 NVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVK 195
N+ +I ++G F + L D ++ G P+F CKP+++ +
Sbjct 112 NINAAGCNFNSYIRRAVRFVGVHVFGLCITALITDIIQLATGYHAPYFLTVCKPNYTTLN 171
Query 196 CKGSNGEYVYVEDFHCMNDAHRVEDARRSFPSGHST 231
++ V+D D + R+SFPS H+T
Sbjct 172 ISCDENSFI-VDDICSGPDPAAINSGRKSFPSQHAT 206
> dre:335485 ppap2c, fj16e10, wu:fj16e10, zgc:66434; phosphatidic
acid phosphatase type 2C (EC:3.1.3.4); K01080 phosphatidate
phosphatase [EC:3.1.3.4]
Length=273
Score = 52.0 bits (123), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 44/154 (28%), Positives = 64/154 (41%), Gaps = 22/154 (14%)
Query 78 RGSFCNNTDIALPKKKGSINLGQLMVLSFVVPSIIIILVELLIALVRATEDKEAQQSSNV 137
RG FC + I P K +I L ++ +II E A + ++ + S N
Sbjct 34 RGIFCQDESIGYPVKTDTITNVTLAAVTITCTILIICSGE---AYLVYSKKIHSNSSFN- 89
Query 138 RMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCK 197
Q++ +Y LG F F A + D K +G RP+F C P CK
Sbjct 90 --------QYVSAIYKVLGAFLFGGAVSQSLTDLAKYTIGRPRPNFLAVCAPK----VCK 137
Query 198 GSNGEYVYVEDFHCMNDAHRVEDARRSFPSGHST 231
G +V +C + V +AR SF SGHS+
Sbjct 138 G------FVNLNNCTGNPADVTEARLSFYSGHSS 165
> mmu:229791 D3Bwg0562e, A330086D10, Lppr4, PRG-1, mKIAA0455;
DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
(EC:3.1.3.4)
Length=766
Score = 50.4 bits (119), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 31/131 (23%), Positives = 58/131 (44%), Gaps = 1/131 (0%)
Query 101 LMVLSFVVPSIIIILVELLIALVRATEDKEAQQSSNVRMFCWEVPQWIVDLYTYLGGFGF 160
L+ L+F P+I I++ E ++ + A N+ ++ ++G F
Sbjct 126 LLSLAFAGPAITIMVGEGILYCCLSKRRNGAGLEPNINAGGCNFNSFLRRAVRFVGVHVF 185
Query 161 TMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMNDAHRVED 220
+ + L D ++ G P+F CKP+++ + Y+ VED +D +
Sbjct 186 GLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYI-VEDICSGSDLTVINS 244
Query 221 ARRSFPSGHST 231
R+SFPS H+T
Sbjct 245 GRKSFPSQHAT 255
> dre:563806 Lipid phosphate phosphohydrolase 2-like; K01080 phosphatidate
phosphatase [EC:3.1.3.4]
Length=365
Score = 50.1 bits (118), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 42/154 (27%), Positives = 66/154 (42%), Gaps = 22/154 (14%)
Query 78 RGSFCNNTDIALPKKKGSINLGQLMVLSFVVPSIIIILVELLIALVRATEDKEAQQSSNV 137
RG +CN+ I P + +I+ + ++ IIII E + K +S+
Sbjct 69 RGVYCNDETIQYPYRPDTISHKMMAAVTISCSVIIIISGEAYLVYT-----KRLYSNSDF 123
Query 138 RMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCK 197
Q+ LY +G F F + D K +G LRP+F C P C+
Sbjct 124 N-------QYAAALYKVVGTFLFGACVSQSLTDMAKYTIGRLRPNFMSVCAP----AVCE 172
Query 198 GSNGEYVYVEDFHCMNDAHRVEDARRSFPSGHST 231
G Y+ + +C +A V ++R SF SGHS+
Sbjct 173 G------YMLEINCTGNARNVTESRLSFYSGHSS 200
> mmu:235044 Lppr2, MGC25492, PRG-4; cDNA sequence BC018242 (EC:3.1.3.4)
Length=343
Score = 49.7 bits (117), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 51/212 (24%), Positives = 90/212 (42%), Gaps = 20/212 (9%)
Query 28 AGVPSSLKRSLGFSLGRVIPSYPI--RVLMHILSLLAVCLIAANSLTGTATVRGSFCNNT 85
AG LKRS +IP + VL+ I+ LLA L ++ +G FC ++
Sbjct 2 AGGRPHLKRSFS-----IIPCFVFVESVLLGIVVLLAYRLEFTDTFP--VHTQGFFCYDS 54
Query 86 DIA--LPKKKGSINLGQLMVLSFVV--PSIIIILVEL--LIALVRATEDKEAQQSSNVRM 139
A P + + ++ + V P++ I+L EL + + +S+ V
Sbjct 55 AYAKPYPGPEAASRAPPALIYALVTAGPTLTILLGELARAFFPAPPSSSPVSGESTIVSG 114
Query 140 FCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCKGS 199
C + L +LG + F + T +FA++ + G+ PHF C+P+++ + C
Sbjct 115 ACCRFSPPLRRLVRFLGVYSFGLFTTTIFANAGQVVTGNPTPHFLSVCRPNYTALGCPPP 174
Query 200 NGEYVYVEDF-----HCMNDAHRVEDARRSFP 226
+ + + F C V ARR+FP
Sbjct 175 SPDRPGPDRFVTDQSACAGSPSLVAAARRAFP 206
> hsa:9890 LPPR4, KIAA0455, LPR4, PHP1, PRG-1, PRG1, RP4-788L13.1;
lipid phosphate phosphatase-related protein type 4 (EC:3.1.3.4)
Length=705
Score = 48.1 bits (113), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 30/131 (22%), Positives = 57/131 (43%), Gaps = 1/131 (0%)
Query 101 LMVLSFVVPSIIIILVELLIALVRATEDKEAQQSSNVRMFCWEVPQWIVDLYTYLGGFGF 160
L+ L+F P+I I++ E ++ + N+ ++ ++G F
Sbjct 125 LLSLAFAGPAITIMVGEGILYCCLSKRRNGVGLEPNINAGGCNFNSFLRRAVRFVGVHVF 184
Query 161 TMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMNDAHRVED 220
+ + L D ++ G P+F CKP+++ + Y+ VED +D +
Sbjct 185 GLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYI-VEDICSGSDLTVINS 243
Query 221 ARRSFPSGHST 231
R+SFPS H+T
Sbjct 244 GRKSFPSQHAT 254
> xla:495974 ppapdc1a; phosphatidic acid phosphatase type 2 domain
containing 1A (EC:3.1.3.4)
Length=218
Score = 46.6 bits (109), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 37/131 (28%), Positives = 56/131 (42%), Gaps = 36/131 (27%)
Query 101 LMVLSFVVPSIIIILVELLIALVRATEDKEAQQSSNVRMFCWEVPQWIVDLYTYLGGFGF 160
+ +SF+ P +I +V++++ R TE KEA C V
Sbjct 1 MFAISFLTPLAVIFVVKIILRTDR-TEVKEA---------CLAV--------------SL 36
Query 161 TMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMNDAHRVED 220
+A + +++K VG RP FF C PD + E+ HC DA V +
Sbjct 37 ALALNGVCTNTIKLIVGRPRPDFFYRCFPDG------------ISNEEMHCTGDASLVSE 84
Query 221 ARRSFPSGHST 231
R+SFPS HS+
Sbjct 85 GRKSFPSIHSS 95
> dre:571722 brain-specific phosphatidic acid phosphatase-like
protein 1-like
Length=725
Score = 45.4 bits (106), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 40/160 (25%), Positives = 72/160 (45%), Gaps = 12/160 (7%)
Query 79 GSFCNNTDIALP---KKKGSINLGQLMVLSFVVPSIIIILVE--LLIALVRATEDKEAQQ 133
G C++ ++LP I L+ L+F P+I I++ E L L RA A+
Sbjct 52 GFSCHDRSLSLPYIDPTHEVIPFLMLLSLAFAAPAITIMIGEGILFCCLSRAQCGGGAE- 110
Query 134 SSNVRMFCWEVPQWIVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDWSQ 193
+++ ++ ++G F + L D ++ G P+F CKP+++
Sbjct 111 -ADINAAGCNFNSFVRRGVRFVGVHVFGLCVTALITDIIQLSTGYPAPYFLTVCKPNYTH 169
Query 194 VK--CKGSNGEYVYVEDFHCMNDAHRVEDARRSFPSGHST 231
+ C+ S + +ED DA + +R+SFPS H+T
Sbjct 170 LNTSCEES---FFILEDICSGPDAALINASRKSFPSQHAT 206
> ath:AT3G02600 LPP3; LPP3 (LIPID PHOSPHATE PHOSPHATASE 3); phosphatidate
phosphatase (EC:3.1.3.4)
Length=333
Score = 44.3 bits (103), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 43/197 (21%), Positives = 79/197 (40%), Gaps = 41/197 (20%)
Query 36 RSLGFSLGRV-IPSYPIRVLMHILSLLAVCLIAANSLTGTATVRGSFCNNTDIALPKKKG 94
RS G ++ R + + I VL+ IL + + + G + TD++ P K
Sbjct 31 RSHGMTVARTHMHDWIILVLLVILECVLLIIHPFYRFVGKDMM-------TDLSYPLKSN 83
Query 95 SINLGQLMVLSFVVPSIIIILVELLIALVRATEDKEAQQSSNVRMFCWEVPQWIVDLYTY 154
++ + + V + ++P +I I + R + + DL+
Sbjct 84 TVPIWSVPVYAMLLPLVIFIFIYF-----RRRD--------------------VYDLHHA 118
Query 155 LGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMND 214
+ G +++ + D++K VG RP FF C PD Y + D C D
Sbjct 119 VLGLLYSVLVTAVLTDAIKNAVGRPRPDFFWRCFPD--------GKALYDSLGDVICHGD 170
Query 215 AHRVEDARRSFPSGHST 231
+ + +SFPSGH++
Sbjct 171 KSVIREGHKSFPSGHTS 187
> dre:431758 ppapdc1b, fc49c04, wu:fc49c04, zgc:92365; phosphatidic
acid phosphatase type 2 domain containing 1B (EC:3.1.3.4)
Length=266
Score = 43.5 bits (101), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 12/71 (16%)
Query 161 TMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMNDAHRVED 220
T+ +F +++K VG RP FF C PD Q+ + HC D V +
Sbjct 95 TLVLNGVFTNAVKLAVGRPRPDFFYRCFPD-GQMN-----------PELHCSGDPDVVME 142
Query 221 ARRSFPSGHST 231
R+SFPSGHS+
Sbjct 143 GRKSFPSGHSS 153
> xla:443950 ppapdc1b, MGC80318; phosphatidic acid phosphatase
type 2 domain containing 1B (EC:3.1.3.4)
Length=226
Score = 43.1 bits (100), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 34/136 (25%), Positives = 56/136 (41%), Gaps = 36/136 (26%)
Query 96 INLGQLMVLSFVVPSIIIILVELLIALVRATEDKEAQQSSNVRMFCWEVPQWIVDLYTYL 155
I + ++SF+ P ++ L L T+ +EA ++++
Sbjct 14 IPTNSMFLISFLTPLSVVALARLFWK-ADGTDSREAGLAASL------------------ 54
Query 156 GGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMNDA 215
++A +F +++K VG RP F C PD + S G HC D
Sbjct 55 -----SLALNGIFTNTVKLIVGRPRPDFLFRCFPDGQE-----SPG-------LHCTGDP 97
Query 216 HRVEDARRSFPSGHST 231
V + R+SFPSGHS+
Sbjct 98 ELVIEGRKSFPSGHSS 113
> mmu:216152 KIAA4076, Lppr3, Prg2; cDNA sequence BC005764 (EC:3.1.3.4)
Length=454
Score = 42.4 bits (98), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Query 154 YLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMN 213
++G F + L D ++ G P F CKP+++ + + Y+ +D +
Sbjct 131 FVGVHVFGLCATALVTDVIQLATGYHTPFFLTVCKPNYTLLGTSCESNPYI-TQDICSGH 189
Query 214 DAHRVEDARRSFPSGHST 231
D H + AR++FPS H+T
Sbjct 190 DTHAILSARKTFPSQHAT 207
> hsa:84513 PPAPDC1B, DPPL1, HTPAP; phosphatidic acid phosphatase
type 2 domain containing 1B (EC:3.1.3.4)
Length=264
Score = 41.6 bits (96), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 12/65 (18%)
Query 167 LFADSLKCFVGSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMNDAHRVEDARRSFP 226
+F +++K VG RP FF C PD + D C D V + R+SFP
Sbjct 102 VFTNTIKLIVGRPRPDFFYRCFPDG------------LAHSDLMCTGDKDVVNEGRKSFP 149
Query 227 SGHST 231
SGHS+
Sbjct 150 SGHSS 154
> ath:AT2G01180 ATPAP1; ATPAP1 (PHOSPHATIDIC ACID PHOSPHATASE
1); phosphatidate phosphatase (EC:3.1.3.4)
Length=327
Score = 41.2 bits (95), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 8/84 (9%)
Query 148 IVDLYTYLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCKGSNGEYVYVE 207
+ DL+ + G F + + DS+K G RP+F+ C PD ++ Y +
Sbjct 118 VYDLHHSILGLLFAVLITGVITDSIKVATGRPRPNFYWRCFPDGKEL--------YDALG 169
Query 208 DFHCMNDAHRVEDARRSFPSGHST 231
C A V++ +SFPSGH++
Sbjct 170 GVVCHGKAAEVKEGHKSFPSGHTS 193
> hsa:196051 PPAPDC1A, DPPL2, MGC120299, MGC120300, PPAPDC1; phosphatidic
acid phosphatase type 2 domain containing 1A (EC:3.1.3.4)
Length=271
Score = 40.4 bits (93), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 31/131 (23%), Positives = 52/131 (39%), Gaps = 36/131 (27%)
Query 101 LMVLSFVVPSIIIILVELLIALVRATEDKEAQQSSNVRMFCWEVPQWIVDLYTYLGGFGF 160
+ +SF+ P +I +V++ +R T+ E +++
Sbjct 54 MFAISFLTPLAVICVVKI----IRRTDKTEIKEA--------------------FLAVSL 89
Query 161 TMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMNDAHRVED 220
+A + +++K VG RP FF C PD V + HC D V +
Sbjct 90 ALALNGVCTNTIKLIVGRPRPDFFYRCFPDG------------VMNSEMHCTGDPDLVSE 137
Query 221 ARRSFPSGHST 231
R+SFPS HS+
Sbjct 138 GRKSFPSIHSS 148
> mmu:71910 Ppapdc1b, 1810019D05Rik, 2310022A04Rik, AW045471,
Ppapdc1; phosphatidic acid phosphatase type 2 domain containing
1B (EC:3.1.3.4)
Length=260
Score = 40.0 bits (92), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 12/65 (18%)
Query 167 LFADSLKCFVGSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMNDAHRVEDARRSFP 226
+F + +K VG RP FF C PD + D C D V + R+SFP
Sbjct 98 VFTNIIKLIVGRPRPDFFYRCFPDG------------LAHSDLTCTGDEDVVNEGRKSFP 145
Query 227 SGHST 231
SGHS+
Sbjct 146 SGHSS 150
> hsa:79948 LPPR3, LPR3, PRG-2, PRG2; lipid phosphate phosphatase-related
protein type 3 (EC:3.1.3.4)
Length=746
Score = 40.0 bits (92), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
Query 154 YLGGFGFTMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMN 213
++G F + L D ++ G P F CKP+++ + Y+ +D +
Sbjct 133 FVGVHVFGLCATALVTDVIQLATGYHTPFFLTVCKPNYTLLGTSCEVNPYI-TQDICSGH 191
Query 214 DAHRVEDARRSFPSGHST 231
D H + AR++FPS H+T
Sbjct 192 DIHAILSARKTFPSQHAT 209
> dre:100334794 phosphatidic acid phosphatase type 2C-like
Length=282
Score = 39.7 bits (91), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 36/131 (27%)
Query 101 LMVLSFVVPSIIIILVELLIALVRATEDKEAQQSSNVRMFCWEVPQWIVDLYTYLGGFGF 160
+ +SF+ P +I +V+++ R TE KEA C V
Sbjct 61 MFAISFLTPLAVIFVVKIIQRTDR-TEIKEA---------CLAV--------------SL 96
Query 161 TMATAWLFADSLKCFVGSLRPHFFDACKPDWSQVKCKGSNGEYVYVEDFHCMNDAHRVED 220
+A +F +++K VG RP ++ C PD Q+ K C + V +
Sbjct 97 ALALNGVFTNTIKLIVGRPRPDYYQRCFPD-GQMNAK-----------MLCTGEPDLVSE 144
Query 221 ARRSFPSGHST 231
R+SFPS HS+
Sbjct 145 GRKSFPSSHSS 155
Lambda K H
0.323 0.136 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 7825241528
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
Posted date: Sep 17, 2011 11:19 AM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40