bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
164,496 sequences; 82,071,388 total letters
Query= Emax_0757_orf1
Length=209
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_111360 cGMP-dependent protein kinase, putative (EC:... 431 8e-121
pfa:PF14_0346 PKG; cGMP-dependent protein kinase (EC:2.7.11.12... 380 2e-105
bbo:BBOV_I004690 19.m02237; cGMP dependent protein kinase (EC:... 368 7e-102
cpv:cgd8_750 cyclic nucleotide (cGMP)-dependent protein kinase... 350 1e-96
tpv:TP03_0511 cGMP-dependent protein kinase (EC:2.7.1.37); K07... 318 1e-86
tgo:TGME49_086470 cAMP-dependent protein kinase catalytic subu... 195 1e-49
dre:561941 protein kinase, X-linked-like; K04345 protein kinas... 194 2e-49
hsa:5613 PRKX, PKX1; protein kinase, X-linked (EC:2.7.11.1); K... 189 7e-48
dre:564064 prkacaa, zgc:158799; protein kinase, cAMP-dependent... 189 8e-48
xla:380388 prkacb, MGC53163, XPKAbeta, kin-1, pkacb, prkacba; ... 188 9e-48
cel:ZK909.2 kin-1; protein KINase family member (kin-1); K0434... 188 1e-47
mmu:18747 Prkaca, Cs, PKA, PKCD, Pkaca; protein kinase, cAMP d... 188 1e-47
xla:446502 prkacbb, MGC80071; protein kinase, cAMP-dependent, ... 188 1e-47
mmu:18749 Prkacb, Pkacb; protein kinase, cAMP dependent, catal... 188 1e-47
hsa:5567 PRKACB, DKFZp781I2452, MGC41879, MGC9320, PKACB; prot... 188 1e-47
hsa:5566 PRKACA, MGC102831, MGC48865, PKACA; protein kinase, c... 187 2e-47
xla:100101276 prkaca; protein kinase, cAMP-dependent, catalyti... 187 2e-47
tgo:TGME49_026030 cAMP-dependent protein kinase catalytic subu... 187 2e-47
dre:563147 prkacbb, MGC110804, prkacb, wu:fz54b03, zgc:110804;... 186 6e-47
dre:445076 prkacab, zgc:91856; protein kinase, cAMP-dependent,... 186 7e-47
mmu:19108 Prkx, PKX1, Pkare; protein kinase, X-linked (EC:2.7.... 183 3e-46
cpv:cgd3_3040 protein kinase, cAMP-dependent, catalytic chain ... 183 5e-46
dre:394005 prkg1a, MGC63955, prkg1, zgc:63955; protein kinase,... 182 6e-46
dre:393998 prkacba, MGC64054, Prkacb, zgc:64054; protein kinas... 181 1e-45
dre:100125912 prkg2; protein kinase, cGMP-dependent, type II (... 181 1e-45
hsa:5568 PRKACG, KAPG, PKACg; protein kinase, cAMP-dependent, ... 180 2e-45
sce:YKL166C TPK3; Tpk3p (EC:2.7.11.11); K04345 protein kinase ... 179 5e-45
dre:566430 cGMP dependent protein kinase I 179 6e-45
tgo:TGME49_028420 cAMP-dependent protein kinase catalytic subu... 179 8e-45
mmu:19091 Prkg1, AW125416, CGKI, MGC132849, Prkg1b, Prkgr1b; p... 178 1e-44
hsa:5592 PRKG1, CGKI, DKFZp686K042, FLJ36117, MGC71944, PGK, P... 178 1e-44
sce:YPL203W TPK2, PKA2, PKA3, YKR1; Tpk2p (EC:2.7.11.11); K043... 178 2e-44
xla:444025 prkg2, MGC82580; protein kinase, cGMP-dependent, ty... 176 5e-44
sce:YJL164C TPK1, PKA1, SRA3; Tpk1p (EC:2.7.11.11); K04345 pro... 175 1e-43
pfa:PFI1685w PfPKAc, PfPKA, PKA; cAMP-dependent protein kinase... 174 1e-43
hsa:5593 PRKG2, PRKGR2, cGKII; protein kinase, cGMP-dependent,... 174 2e-43
cel:F55A8.2 egl-4; EGg Laying defective family member (egl-4);... 174 2e-43
hsa:6197 RPS6KA3, CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RS... 174 2e-43
mmu:110651 Rps6ka3, MPK-9, Rsk2, S6K-alpha3, pp90RSK2; ribosom... 174 2e-43
bbo:BBOV_III005740 17.m07511; protein kinase domain containing... 173 3e-43
mmu:19092 Prkg2, AW212535, CGKII, MGC130517, Prkgr2, cGK-II; p... 172 5e-43
pfa:PFL2250c PKB; rac-beta serine/threonine protein kinase, Pf... 172 1e-42
cel:F47F2.1 hypothetical protein; K04345 protein kinase A [EC:... 172 1e-42
sce:YHR205W SCH9, HRM2, KOM1; Protein kinase involved in trans... 171 2e-42
hsa:6196 RPS6KA2, HU-2, MAPKAPK1C, RSK, RSK3, S6K-alpha, S6K-a... 170 3e-42
cel:T01H8.1 rskn-1; RSK-pNinety (RSK-p90 kinase) homolog famil... 170 3e-42
xla:399376 rps6ka3, MGC82193, S6KII, p90, rsk, rsk2; ribosomal... 170 3e-42
mmu:20112 Rps6ka2, 90kDa, D17Wsu134e, Rps6ka-rs1, Rsk3, p90rsk... 169 5e-42
dre:556339 protein kinase, cGMP-dependent, type II-like; K0737... 169 7e-42
dre:571285 ribosomal protein S6 kinase, polypeptide 2-like; K0... 169 8e-42
> tgo:TGME49_111360 cGMP-dependent protein kinase, putative (EC:2.7.11.12);
K07376 protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=994
Score = 431 bits (1109), Expect = 8e-121, Method: Compositional matrix adjust.
Identities = 202/209 (96%), Positives = 204/209 (97%), Gaps = 0/209 (0%)
Query 1 NDHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYL 60
NDHPFIIRLVRTFRDK+FLYFLTELVTGGELYDAIRKLGLL R QAQFYLASIVLAIEYL
Sbjct 739 NDHPFIIRLVRTFRDKEFLYFLTELVTGGELYDAIRKLGLLARSQAQFYLASIVLAIEYL 798
Query 61 HERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTL 120
HERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTL
Sbjct 799 HERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTL 858
Query 121 TADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLC 180
TADTWAFGVCLYEFMCGPLPFGNDAEDQL IFRDIL GKL+FPHYVTDQDAINLMKRLLC
Sbjct 859 TADTWAFGVCLYEFMCGPLPFGNDAEDQLEIFRDILTGKLVFPHYVTDQDAINLMKRLLC 918
Query 181 RLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
RLPEVRIGCSINGYKDIKEHAFF DFDWD
Sbjct 919 RLPEVRIGCSINGYKDIKEHAFFGDFDWD 947
> pfa:PF14_0346 PKG; cGMP-dependent protein kinase (EC:2.7.11.12);
K07376 protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=853
Score = 380 bits (976), Expect = 2e-105, Method: Compositional matrix adjust.
Identities = 174/209 (83%), Positives = 188/209 (89%), Gaps = 0/209 (0%)
Query 1 NDHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYL 60
NDHPFIIRLVRTF+D + YFLTELVTGGELYDAIRKLGLL + QAQFYL SI+LAIEYL
Sbjct 596 NDHPFIIRLVRTFKDSKYFYFLTELVTGGELYDAIRKLGLLSKSQAQFYLGSIILAIEYL 655
Query 61 HERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTL 120
HERNI YRDLKPENILLD QGYVKLIDFGCAKK+QGRAYTLVGTPHYMAPEVILGKGY
Sbjct 656 HERNIVYRDLKPENILLDKQGYVKLIDFGCAKKVQGRAYTLVGTPHYMAPEVILGKGYGC 715
Query 121 TADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLC 180
T D WA G+CLYEF+CGPLPFGND EDQL IFRDIL G+L FP YVTD D+INLMKRLLC
Sbjct 716 TVDIWALGICLYEFICGPLPFGNDEEDQLEIFRDILTGQLTFPDYVTDTDSINLMKRLLC 775
Query 181 RLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
RLP+ RIGCSING+KDIK+H FFS+F+WD
Sbjct 776 RLPQGRIGCSINGFKDIKDHPFFSNFNWD 804
> bbo:BBOV_I004690 19.m02237; cGMP dependent protein kinase (EC:2.7.11.1);
K07376 protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=887
Score = 368 bits (945), Expect = 7e-102, Method: Compositional matrix adjust.
Identities = 165/209 (78%), Positives = 190/209 (90%), Gaps = 0/209 (0%)
Query 1 NDHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYL 60
NDHPFII+LV+TF+D+ +YFLTEL+TGGELYDAIRK+GLL R QAQFY+ASIVLA EYL
Sbjct 632 NDHPFIIQLVKTFKDESNVYFLTELITGGELYDAIRKIGLLSRPQAQFYIASIVLAFEYL 691
Query 61 HERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTL 120
HER IAYRDLKPENILLD QGY+KLIDFGCAKK++GRAYTL+GTPHYMAPE+ILGKGY
Sbjct 692 HERQIAYRDLKPENILLDEQGYIKLIDFGCAKKIKGRAYTLIGTPHYMAPEIILGKGYGC 751
Query 121 TADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLC 180
AD W+FGVCLYEF+CGPLPFGNDA DQ+ IFRDIL G L+FP YV DQ+AIN++KRLLC
Sbjct 752 LADIWSFGVCLYEFICGPLPFGNDARDQIEIFRDILKGNLVFPEYVKDQEAINIIKRLLC 811
Query 181 RLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
R+PEVR+G SING+KDIKEH++F DFDWD
Sbjct 812 RVPEVRLGSSINGFKDIKEHSYFRDFDWD 840
> cpv:cgd8_750 cyclic nucleotide (cGMP)-dependent protein kinase
with 3 cNMP binding domains and a Ser/Thr kinase domain ;
K07376 protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=965
Score = 350 bits (899), Expect = 1e-96, Method: Composition-based stats.
Identities = 149/209 (71%), Positives = 182/209 (87%), Gaps = 0/209 (0%)
Query 1 NDHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYL 60
NDHPFII+LVRTF+D + +Y LTEL+ GGELYDA++++GLL RYQAQFY+ SI+LA+EYL
Sbjct 677 NDHPFIIKLVRTFKDSENIYLLTELIPGGELYDALQRIGLLTRYQAQFYIGSIILALEYL 736
Query 61 HERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTL 120
HER+I YRDLKPENILLDSQGY+KLIDFGCAKK+ GR+YTL GTPHYMAPEVILGKGY L
Sbjct 737 HERSIVYRDLKPENILLDSQGYIKLIDFGCAKKIAGRSYTLAGTPHYMAPEVILGKGYNL 796
Query 121 TADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLC 180
+ D WA G+CLYEF+CG LPFGNDA D L IF+DIL KL+FP ++ D D +N++KRLLC
Sbjct 797 SCDAWAIGICLYEFLCGCLPFGNDAVDHLEIFKDILTSKLVFPRHLNDVDTVNIIKRLLC 856
Query 181 RLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
R+PEVR+GCS GYK+IK++ FF DF++D
Sbjct 857 RVPEVRMGCSATGYKEIKDNVFFKDFNFD 885
> tpv:TP03_0511 cGMP-dependent protein kinase (EC:2.7.1.37); K07376
protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=892
Score = 318 bits (814), Expect = 1e-86, Method: Compositional matrix adjust.
Identities = 143/209 (68%), Positives = 174/209 (83%), Gaps = 7/209 (3%)
Query 1 NDHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYL 60
NDHPFII+LV+TF+D++ +YFLTELVTGGEL+DA+RKL LL + QAQFYL SI+LA+EYL
Sbjct 647 NDHPFIIQLVKTFKDEENIYFLTELVTGGELFDALRKLELLKKPQAQFYLGSIILALEYL 706
Query 61 HERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTL 120
HER I YRDLKPEN++LD QGY+KLIDFG AKK++GR +T++GTP YMAPEVI+GKGY
Sbjct 707 HERQIIYRDLKPENVMLDHQGYIKLIDFGSAKKIEGRTFTVIGTPQYMAPEVIMGKGYNC 766
Query 121 TADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLC 180
AD W+ GVCLYEF+CGPLPFG+DA DQ +F+ FP ++ DQD INL+KRLLC
Sbjct 767 MADIWSIGVCLYEFICGPLPFGDDAVDQFDVFKK-------FPDFLRDQDGINLIKRLLC 819
Query 181 RLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
R E+RIG SING+KDIKEH +F DFDWD
Sbjct 820 RKTELRIGNSINGFKDIKEHPYFRDFDWD 848
> tgo:TGME49_086470 cAMP-dependent protein kinase catalytic subunit
(EC:2.7.11.11); K04345 protein kinase A [EC:2.7.11.11]
Length=514
Score = 195 bits (495), Expect = 1e-49, Method: Compositional matrix adjust.
Identities = 97/207 (46%), Positives = 135/207 (65%), Gaps = 3/207 (1%)
Query 2 DHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLH 61
+HPFI+ L+ F+D+ L+ L E V GGEL+ +R+ + QA+ Y A I LA +YLH
Sbjct 260 EHPFIVNLLAAFQDEKRLFILMEYVNGGELFSHLRRRNCIPTDQARLYAAEITLAFQYLH 319
Query 62 ERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLT 121
+R+I YRDLKPEN+L+DSQG++K+ DFG AK ++ R +TL GT Y+APE I +G+ L
Sbjct 320 QRHIVYRDLKPENLLIDSQGHIKITDFGFAKVVKDRTWTLCGTHEYLAPESITRRGHGLP 379
Query 122 ADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCR 181
D WA G+ L+E + G PF + E+ L I+R I+AGK+ FP D A +L+KRLL
Sbjct 380 VDWWALGILLFEMLAGHPPFVD--ENPLGIYRKIIAGKIEFPRSF-DYAAKSLVKRLLTH 436
Query 182 LPEVRIGCSINGYKDIKEHAFFSDFDW 208
P R GC +G +D+K H FF DW
Sbjct 437 DPLKRYGCLKDGAEDVKNHKFFKGIDW 463
> dre:561941 protein kinase, X-linked-like; K04345 protein kinase
A [EC:2.7.11.11]
Length=357
Score = 194 bits (494), Expect = 2e-49, Method: Compositional matrix adjust.
Identities = 99/208 (47%), Positives = 131/208 (62%), Gaps = 3/208 (1%)
Query 2 DHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLH 61
+HPF++RL T D FLY L E V GGEL+ +R G FY A IV AIEYLH
Sbjct 104 NHPFLVRLFWTHHDDRFLYMLMEYVNGGELFSYLRSRGHFSNSTGMFYSAEIVCAIEYLH 163
Query 62 ERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLT 121
+ I YRDLKPENILLDS+G+++L DFG AKK+ R +TL GTP Y+APEVI KG+
Sbjct 164 SKEIVYRDLKPENILLDSEGHIRLTDFGFAKKLSERTWTLCGTPEYLAPEVIQSKGHGRA 223
Query 122 ADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCR 181
D WA GV ++E + G PF +D + I++ ILAGKL FP ++ D +L+K+ L
Sbjct 224 VDWWALGVLIFEMLAGYPPFFDD--NPFGIYQKILAGKLEFPRHL-DLYVKDLIKKFLVT 280
Query 182 LPEVRIGCSINGYKDIKEHAFFSDFDWD 209
E R+G NG D+K+H +F +W+
Sbjct 281 DRERRLGNMKNGADDVKKHRWFKSVNWE 308
> hsa:5613 PRKX, PKX1; protein kinase, X-linked (EC:2.7.11.1);
K04345 protein kinase A [EC:2.7.11.11]
Length=358
Score = 189 bits (480), Expect = 7e-48, Method: Compositional matrix adjust.
Identities = 98/207 (47%), Positives = 129/207 (62%), Gaps = 3/207 (1%)
Query 3 HPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHE 62
HPF+IRL T+ D+ FLY L E V GGEL+ +R G FY A I+ AIEYLH
Sbjct 106 HPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHS 165
Query 63 RNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLTA 122
+ I YRDLKPENILLD G++KL DFG AKK+ R +TL GTP Y+APEVI KG+
Sbjct 166 KEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAV 225
Query 123 DTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCRL 182
D WA G+ ++E + G PF +D + I++ ILAGK+ FP ++ D +L+K+LL
Sbjct 226 DWWALGILIFEMLSGFPPFFDD--NPFGIYQKILAGKIDFPRHL-DFHVKDLIKKLLVVD 282
Query 183 PEVRIGCSINGYKDIKEHAFFSDFDWD 209
R+G NG D+K H +F DW+
Sbjct 283 RTRRLGNMKNGANDVKHHRWFRSVDWE 309
> dre:564064 prkacaa, zgc:158799; protein kinase, cAMP-dependent,
catalytic, alpha, genome duplicate a (EC:2.7.11.11); K04345
protein kinase A [EC:2.7.11.11]
Length=352
Score = 189 bits (479), Expect = 8e-48, Method: Compositional matrix adjust.
Identities = 93/205 (45%), Positives = 129/205 (62%), Gaps = 3/205 (1%)
Query 4 PFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHER 63
PF++RL +F+D LY + E V GGE++ +R++G A+FY A IVL EYLH
Sbjct 103 PFLVRLEHSFKDNTNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 162
Query 64 NIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLTAD 123
++ YRDLKPEN+L+D QGY+++ DFG AK+++GR +TL GTP Y+APE+IL KGY D
Sbjct 163 DLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVD 222
Query 124 TWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCRLP 183
WA GV +YE G PF D Q I+ I++GK+ FP + + D +L++ LL
Sbjct 223 WWALGVLIYEMAAGYPPFFADQPIQ--IYEKIVSGKVRFPSHFSS-DLKDLLRNLLQVDL 279
Query 184 EVRIGCSINGYKDIKEHAFFSDFDW 208
R G NG DIK H +F+ DW
Sbjct 280 TKRFGNLKNGVNDIKGHKWFATTDW 304
> xla:380388 prkacb, MGC53163, XPKAbeta, kin-1, pkacb, prkacba;
protein kinase, cAMP-dependent, catalytic, beta; K04345 protein
kinase A [EC:2.7.11.11]
Length=351
Score = 188 bits (478), Expect = 9e-48, Method: Compositional matrix adjust.
Identities = 93/205 (45%), Positives = 129/205 (62%), Gaps = 3/205 (1%)
Query 4 PFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHER 63
PF++RL +F+D LY + E V GGE++ +R++G A+FY A IVL EYLH
Sbjct 102 PFLVRLEYSFKDNSNLYMIMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 161
Query 64 NIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLTAD 123
++ YRDLKPEN+L+D QGY+++ DFG AK+++GR +TL GTP Y+APE+IL KGY D
Sbjct 162 DLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVD 221
Query 124 TWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCRLP 183
WA GV +YE G PF D Q I+ I++GK+ FP + + D +L++ LL
Sbjct 222 WWALGVLIYEMAAGYPPFFADQPIQ--IYEKIVSGKVRFPSHFS-SDLKDLLRNLLQVDL 278
Query 184 EVRIGCSINGYKDIKEHAFFSDFDW 208
R G NG DIK H +F+ DW
Sbjct 279 TKRYGNLKNGVNDIKNHKWFATTDW 303
> cel:ZK909.2 kin-1; protein KINase family member (kin-1); K04345
protein kinase A [EC:2.7.11.11]
Length=381
Score = 188 bits (478), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 92/207 (44%), Positives = 131/207 (63%), Gaps = 3/207 (1%)
Query 2 DHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLH 61
D PF++ + +F+D LY + E ++GGE++ +R++G ++FY A IVLA EYLH
Sbjct 130 DFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLH 189
Query 62 ERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLT 121
++ YRDLKPEN+L+DS GY+K+ DFG AK+++GR +TL GTP Y+APE+IL KGY
Sbjct 190 SLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKA 249
Query 122 ADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCR 181
D WA GV +YE G PF D Q I+ I++GK+ FP + +++ +L+K LL
Sbjct 250 VDWWALGVLIYEMAAGYPPFFADQPIQ--IYEKIVSGKVKFPSHFSNE-LKDLLKNLLQV 306
Query 182 LPEVRIGCSINGYKDIKEHAFFSDFDW 208
R G NG DIK H +F DW
Sbjct 307 DLTKRYGNLKNGVADIKNHKWFGSTDW 333
> mmu:18747 Prkaca, Cs, PKA, PKCD, Pkaca; protein kinase, cAMP
dependent, catalytic, alpha (EC:2.7.11.11); K04345 protein
kinase A [EC:2.7.11.11]
Length=351
Score = 188 bits (478), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 92/205 (44%), Positives = 129/205 (62%), Gaps = 3/205 (1%)
Query 4 PFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHER 63
PF+++L +F+D LY + E V GGE++ +R++G A+FY A IVL EYLH
Sbjct 102 PFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 161
Query 64 NIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLTAD 123
++ YRDLKPEN+L+D QGY+++ DFG AK+++GR +TL GTP Y+APE+IL KGY D
Sbjct 162 DLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVD 221
Query 124 TWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCRLP 183
WA GV +YE G PF D Q I+ I++GK+ FP + + D +L++ LL
Sbjct 222 WWALGVLIYEMAAGYPPFFADQPIQ--IYEKIVSGKVRFPSHFSS-DLKDLLRNLLQVDL 278
Query 184 EVRIGCSINGYKDIKEHAFFSDFDW 208
R G NG DIK H +F+ DW
Sbjct 279 TKRFGNLKNGVNDIKNHKWFATTDW 303
> xla:446502 prkacbb, MGC80071; protein kinase, cAMP-dependent,
catalytic, beta b; K04345 protein kinase A [EC:2.7.11.11]
Length=351
Score = 188 bits (477), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 93/205 (45%), Positives = 129/205 (62%), Gaps = 3/205 (1%)
Query 4 PFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHER 63
PF++RL +F+D LY + E V GGE++ +R++G A+FY + IVL EYLH
Sbjct 102 PFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHAL 161
Query 64 NIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLTAD 123
++ YRDLKPEN+L+D QGY+++ DFG AK+++GR +TL GTP Y+APE+IL KGY D
Sbjct 162 DLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVD 221
Query 124 TWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCRLP 183
WA GV +YE G PF D Q I+ I++GK+ FP + + D +L++ LL
Sbjct 222 WWALGVLIYEMAAGYPPFFADQPIQ--IYEKIVSGKVRFPSHFSS-DLKDLLRNLLQVDL 278
Query 184 EVRIGCSINGYKDIKEHAFFSDFDW 208
R G NG DIK H +FS DW
Sbjct 279 TKRFGNLKNGVTDIKGHKWFSTTDW 303
> mmu:18749 Prkacb, Pkacb; protein kinase, cAMP dependent, catalytic,
beta (EC:2.7.11.11); K04345 protein kinase A [EC:2.7.11.11]
Length=338
Score = 188 bits (477), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 93/207 (44%), Positives = 130/207 (62%), Gaps = 3/207 (1%)
Query 2 DHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLH 61
+ PF++RL +F+D LY + E V GGE++ +R++G A+FY A IVL EYLH
Sbjct 87 EFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 146
Query 62 ERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLT 121
++ YRDLKPEN+L+D QGY+++ DFG AK+++GR +TL GTP Y+APE+IL KGY
Sbjct 147 SLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKA 206
Query 122 ADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCR 181
D WA GV +YE G PF D Q I+ I++GK+ FP + + D +L++ LL
Sbjct 207 VDWWALGVLIYEMAAGYPPFFADQPIQ--IYEKIVSGKVRFPSHFSS-DLKDLLRNLLQV 263
Query 182 LPEVRIGCSINGYKDIKEHAFFSDFDW 208
R G NG DIK H +F+ DW
Sbjct 264 DLTKRFGNLKNGVSDIKTHKWFATTDW 290
> hsa:5567 PRKACB, DKFZp781I2452, MGC41879, MGC9320, PKACB; protein
kinase, cAMP-dependent, catalytic, beta (EC:2.7.11.11);
K04345 protein kinase A [EC:2.7.11.11]
Length=351
Score = 188 bits (477), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 93/205 (45%), Positives = 128/205 (62%), Gaps = 3/205 (1%)
Query 4 PFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHER 63
PF++RL F+D LY + E V GGE++ +R++G A+FY A IVL EYLH
Sbjct 102 PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 161
Query 64 NIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLTAD 123
++ YRDLKPEN+L+D QGY+++ DFG AK+++GR +TL GTP Y+APE+IL KGY D
Sbjct 162 DLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVD 221
Query 124 TWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCRLP 183
WA GV +YE G PF D Q I+ I++GK+ FP + + D +L++ LL
Sbjct 222 WWALGVLIYEMAAGYPPFFADQPIQ--IYEKIVSGKVRFPSHFSS-DLKDLLRNLLQVDL 278
Query 184 EVRIGCSINGYKDIKEHAFFSDFDW 208
R G NG DIK H +F+ DW
Sbjct 279 TKRFGNLKNGVSDIKTHKWFATTDW 303
> hsa:5566 PRKACA, MGC102831, MGC48865, PKACA; protein kinase,
cAMP-dependent, catalytic, alpha (EC:2.7.11.11); K04345 protein
kinase A [EC:2.7.11.11]
Length=351
Score = 187 bits (476), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 92/205 (44%), Positives = 129/205 (62%), Gaps = 3/205 (1%)
Query 4 PFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHER 63
PF+++L +F+D LY + E V GGE++ +R++G A+FY A IVL EYLH
Sbjct 102 PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 161
Query 64 NIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLTAD 123
++ YRDLKPEN+L+D QGY+++ DFG AK+++GR +TL GTP Y+APE+IL KGY D
Sbjct 162 DLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVD 221
Query 124 TWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCRLP 183
WA GV +YE G PF D Q I+ I++GK+ FP + + D +L++ LL
Sbjct 222 WWALGVLIYEMAAGYPPFFADQPIQ--IYEKIVSGKVRFPSHFSS-DLKDLLRNLLQVDL 278
Query 184 EVRIGCSINGYKDIKEHAFFSDFDW 208
R G NG DIK H +F+ DW
Sbjct 279 TKRFGNLKNGVNDIKNHKWFATTDW 303
> xla:100101276 prkaca; protein kinase, cAMP-dependent, catalytic,
alpha (EC:2.7.11.1); K04345 protein kinase A [EC:2.7.11.11]
Length=351
Score = 187 bits (476), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 93/205 (45%), Positives = 129/205 (62%), Gaps = 3/205 (1%)
Query 4 PFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHER 63
PF++RL +F+D LY + E V GGE++ +R++G A+FY + IVL EYLH
Sbjct 102 PFLVRLEYSFKDNTNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHAL 161
Query 64 NIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLTAD 123
++ YRDLKPEN+L+D QGY+++ DFG AK+++GR +TL GTP Y+APE+IL KGY D
Sbjct 162 DLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVD 221
Query 124 TWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCRLP 183
WA GV +YE G PF D Q I+ I++GK+ FP + + D +L++ LL
Sbjct 222 WWALGVLIYEMAAGYPPFFADQPIQ--IYEKIVSGKVRFPSHFSS-DLKDLLRNLLQVDL 278
Query 184 EVRIGCSINGYKDIKEHAFFSDFDW 208
R G NG DIK H +FS DW
Sbjct 279 TKRFGNLKNGVTDIKGHKWFSTTDW 303
> tgo:TGME49_026030 cAMP-dependent protein kinase catalytic subunit,
putative (EC:2.7.11.11); K04345 protein kinase A [EC:2.7.11.11]
Length=343
Score = 187 bits (476), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 93/208 (44%), Positives = 135/208 (64%), Gaps = 3/208 (1%)
Query 2 DHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLH 61
+HPF + ++ TF+D +LY + E V GGE + +RK A+FY A + L EYLH
Sbjct 92 NHPFTVNMLGTFKDDRYLYIVMEYVIGGEFFTLLRKTRRFENDAARFYAAQVTLIFEYLH 151
Query 62 ERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLT 121
+RNI YRDLKPEN+L+D++GY+KL DFG AK ++ R YTL GTP Y+APEV+L KG+
Sbjct 152 DRNIIYRDLKPENLLVDAEGYLKLTDFGFAKVIEYRTYTLCGTPEYIAPEVLLNKGHGKP 211
Query 122 ADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCR 181
D W G+ +YE + G PF +D + + +++ IL G++ FP + D++A L+KRLL
Sbjct 212 VDWWTLGILIYEMILGYPPFFDD--EPMGVYQKILGGRIAFPKFF-DKNAKLLVKRLLTP 268
Query 182 LPEVRIGCSINGYKDIKEHAFFSDFDWD 209
R G NG D+K+H +F+ FDW+
Sbjct 269 DLAQRYGNLKNGVADVKDHRWFAGFDWN 296
> dre:563147 prkacbb, MGC110804, prkacb, wu:fz54b03, zgc:110804;
protein kinase, cAMP-dependent, catalytic, beta b; K04345
protein kinase A [EC:2.7.11.11]
Length=351
Score = 186 bits (472), Expect = 6e-47, Method: Compositional matrix adjust.
Identities = 92/205 (44%), Positives = 127/205 (61%), Gaps = 3/205 (1%)
Query 4 PFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHER 63
PF++RL F+D LY + E V GGE++ +R++G A+FY A IVL EYLH
Sbjct 102 PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 161
Query 64 NIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLTAD 123
++ YRDLKPEN+L+D GY+++ DFG AK+++GR +TL GTP Y+APE+IL KGY D
Sbjct 162 DLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVD 221
Query 124 TWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCRLP 183
WA GV +YE G PF D Q I+ I++GK+ FP + + D +L++ LL
Sbjct 222 WWALGVLIYEMAAGYPPFFADQPIQ--IYEKIVSGKVRFPSHFS-SDLKDLLRNLLQVDL 278
Query 184 EVRIGCSINGYKDIKEHAFFSDFDW 208
R G NG DIK H +F+ DW
Sbjct 279 TKRFGNLRNGVNDIKNHKWFATTDW 303
> dre:445076 prkacab, zgc:91856; protein kinase, cAMP-dependent,
catalytic, alpha, genome duplicate b (EC:2.7.11.11); K04345
protein kinase A [EC:2.7.11.11]
Length=351
Score = 186 bits (471), Expect = 7e-47, Method: Compositional matrix adjust.
Identities = 92/205 (44%), Positives = 129/205 (62%), Gaps = 3/205 (1%)
Query 4 PFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHER 63
PF++RL +F+D LY + + V GGE++ +R++G A+FY + IVL EYLH
Sbjct 102 PFLVRLEYSFKDNTNLYMVMQYVQGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHAL 161
Query 64 NIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLTAD 123
++ YRDLKPEN+L+D QGY+++ DFG AK+++GR +TL GTP Y+APE+IL KGY D
Sbjct 162 DLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVD 221
Query 124 TWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCRLP 183
WA GV +YE G PF D Q I+ I++GK+ FP + + D +L++ LL
Sbjct 222 WWALGVLMYEMAAGYPPFFADQPIQ--IYEKIVSGKVRFPSHFSS-DLKDLLRNLLQVDL 278
Query 184 EVRIGCSINGYKDIKEHAFFSDFDW 208
R G NG DIK H +FS DW
Sbjct 279 TKRYGNLKNGVNDIKGHKWFSTTDW 303
> mmu:19108 Prkx, PKX1, Pkare; protein kinase, X-linked (EC:2.7.11.1);
K04345 protein kinase A [EC:2.7.11.11]
Length=355
Score = 183 bits (465), Expect = 3e-46, Method: Compositional matrix adjust.
Identities = 96/208 (46%), Positives = 130/208 (62%), Gaps = 3/208 (1%)
Query 2 DHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLH 61
+HPF+I+L+ T D FLY L E V GGEL+ +R G + FY IV AIEYLH
Sbjct 102 NHPFLIKLLWTGHDNRFLYMLMEFVPGGELFTYLRNRGRFSSVASVFYATEIVCAIEYLH 161
Query 62 ERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLT 121
+ I YRDLKPENILLD +G++KL DFG AKK+ R +TL GTP Y+APEVI KG+
Sbjct 162 SKEIVYRDLKPENILLDREGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRA 221
Query 122 ADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCR 181
D WA G+ ++E + G PF +D + I++ ILA K+ FP + D + +L+K+LL
Sbjct 222 VDWWALGILIFEMLSGFPPFFDD--NPFGIYQKILACKIDFPRQL-DFTSKDLIKKLLVV 278
Query 182 LPEVRIGCSINGYKDIKEHAFFSDFDWD 209
R+G NG +DIK H +F +W+
Sbjct 279 DRTRRLGNMKNGAEDIKRHRWFRGVEWE 306
> cpv:cgd3_3040 protein kinase, cAMP-dependent, catalytic chain
; K04345 protein kinase A [EC:2.7.11.11]
Length=392
Score = 183 bits (464), Expect = 5e-46, Method: Compositional matrix adjust.
Identities = 93/207 (44%), Positives = 132/207 (63%), Gaps = 3/207 (1%)
Query 3 HPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHE 62
HPF++R+ TF+D +LY + E V GGE + +R+ ++FY A +VL EYLH
Sbjct 142 HPFLVRMFGTFKDDRYLYIMMEFVIGGEFFTYLRRCRHFDNETSRFYAAQVVLMFEYLHG 201
Query 63 RNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLTA 122
+NI YRDLKPENIL+D GY+KL DFG AK ++ R +TL GTP Y+APEV+L KG+
Sbjct 202 KNIIYRDLKPENILIDKDGYLKLTDFGFAKAIEYRTFTLCGTPEYIAPEVLLNKGHGKPV 261
Query 123 DTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCRL 182
D W G+ +YE + G PF +D + + I++ ILAGK+ FP Y D++ +L+KRLL
Sbjct 262 DWWTLGILIYEMVVGFPPFYDD--EPMGIYQKILAGKIFFPKYF-DKNCKSLVKRLLTPD 318
Query 183 PEVRIGCSINGYKDIKEHAFFSDFDWD 209
R G G DIK H +F ++D++
Sbjct 319 LTKRYGNLKGGVSDIKLHKWFYNYDFN 345
> dre:394005 prkg1a, MGC63955, prkg1, zgc:63955; protein kinase,
cGMP-dependent, type Ia (EC:2.7.11.1); K07376 protein kinase,
cGMP-dependent [EC:2.7.11.12]
Length=667
Score = 182 bits (463), Expect = 6e-46, Method: Compositional matrix adjust.
Identities = 94/209 (44%), Positives = 130/209 (62%), Gaps = 7/209 (3%)
Query 5 FIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHERN 64
FI+RL RTF+D +LY L E GGEL+ +R G +FY A +V A YLH +
Sbjct 416 FIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGNFDDSTTRFYTACVVEAFAYLHSKG 475
Query 65 IAYRDLKPENILLDSQGYVKLIDFGCAKKM--QGRAYTLVGTPHYMAPEVILGKGYTLTA 122
I YRDLKPEN++LD +GY KL+DFG AKK+ + +T GTP Y+APE+IL KG+ ++A
Sbjct 476 IIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISA 535
Query 123 DTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLM--FPHYVTDQDAINLMKRLLC 180
D W+ G+ +YE + G PF D + + IL G M FP +T ++A NL+K+L
Sbjct 536 DYWSLGILMYELLTGSPPFS--GPDPMKTYNIILRGIDMIEFPKKIT-KNAANLIKKLCR 592
Query 181 RLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
P R+G NG KDI++H +F F+WD
Sbjct 593 DTPSERLGNLKNGVKDIQKHKWFEGFNWD 621
> dre:393998 prkacba, MGC64054, Prkacb, zgc:64054; protein kinase,
cAMP-dependent, catalytic, beta a; K04345 protein kinase
A [EC:2.7.11.11]
Length=395
Score = 181 bits (460), Expect = 1e-45, Method: Compositional matrix adjust.
Identities = 89/205 (43%), Positives = 127/205 (61%), Gaps = 3/205 (1%)
Query 4 PFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHER 63
PF+++L F+D LY + + GGE++ +R++G A+FY A IVL EYLH
Sbjct 146 PFLVKLECAFKDNSNLYMVMRYIQGGEMFSHLRRIGRFSEQNARFYAAQIVLTFEYLHML 205
Query 64 NIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLTAD 123
++ YRDLKPEN+L+D QGY+++ DFG AK+++GR +TL GTP Y+APE+IL KGY D
Sbjct 206 DLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVD 265
Query 124 TWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCRLP 183
WA GV +YE G PF D Q I+ I++GK+ +P + + D +L++ LL
Sbjct 266 WWALGVLIYEMAAGYPPFFADQPIQ--IYEKIVSGKVRYPSHFS-SDLKDLLRNLLQVDL 322
Query 184 EVRIGCSINGYKDIKEHAFFSDFDW 208
R G NG DIK H +F+ DW
Sbjct 323 TKRFGNLKNGVSDIKNHRWFASTDW 347
> dre:100125912 prkg2; protein kinase, cGMP-dependent, type II
(EC:2.7.11.1); K07376 protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=768
Score = 181 bits (460), Expect = 1e-45, Method: Compositional matrix adjust.
Identities = 88/210 (41%), Positives = 133/210 (63%), Gaps = 7/210 (3%)
Query 4 PFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHER 63
PFI+++ RT++D ++Y L E GGE++ +R G Y A+F + + A +YLH
Sbjct 517 PFIVKMYRTYKDNKYVYMLLEACLGGEIWSLLRDRGSFEEYTAKFCVGCVTEAFDYLHNN 576
Query 64 NIAYRDLKPENILLDSQGYVKLIDFGCAKKMQ--GRAYTLVGTPHYMAPEVILGKGYTLT 121
I YRDLKPEN++LD+ GYVKL+DFG AKK++ R +T GTP Y+APE+IL KG+ L+
Sbjct 577 GIIYRDLKPENLMLDTDGYVKLVDFGFAKKLKCGQRTWTFCGTPEYVAPEIILNKGHGLS 636
Query 122 ADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAG--KLMFPHYVTDQDAINLMKRLL 179
D W+ G+ ++E + G PF DQ++I+ IL G K+ FP +T + +L+++L
Sbjct 637 VDFWSLGILIFELLTGSPPF--TGSDQMIIYTFILKGIEKMDFPKKITKRPG-DLIRKLC 693
Query 180 CRLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
+ P R+G NG DIK+H +F+ F W
Sbjct 694 RQNPSERLGNLKNGITDIKKHRWFTGFSWS 723
> hsa:5568 PRKACG, KAPG, PKACg; protein kinase, cAMP-dependent,
catalytic, gamma (EC:2.7.11.11); K04345 protein kinase A [EC:2.7.11.11]
Length=351
Score = 180 bits (457), Expect = 2e-45, Method: Compositional matrix adjust.
Identities = 88/207 (42%), Positives = 131/207 (63%), Gaps = 3/207 (1%)
Query 2 DHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLH 61
D PF+++L +F+D +LY + E V GGE++ ++++G A FY A +VLA++YLH
Sbjct 100 DFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLH 159
Query 62 ERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLT 121
++ +RDLKPEN+L+D QGY+++ DFG AK+++GR +TL GTP Y+APE+IL KGY
Sbjct 160 SLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKA 219
Query 122 ADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCR 181
D WA GV +YE G PF D Q I+ I++G++ FP ++ D +L++ LL
Sbjct 220 VDWWALGVLIYEMAVGFPPFYADQPIQ--IYEKIVSGRVRFPSKLSS-DLKHLLRSLLQV 276
Query 182 LPEVRIGCSINGYKDIKEHAFFSDFDW 208
R G NG DIK H +F+ W
Sbjct 277 DLTKRFGNLRNGVGDIKNHKWFATTSW 303
> sce:YKL166C TPK3; Tpk3p (EC:2.7.11.11); K04345 protein kinase
A [EC:2.7.11.11]
Length=398
Score = 179 bits (455), Expect = 5e-45, Method: Compositional matrix adjust.
Identities = 89/207 (42%), Positives = 130/207 (62%), Gaps = 3/207 (1%)
Query 3 HPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHE 62
HPFIIR+ TF+D ++ + + + GGEL+ +RK A+FY A + LA+EYLH
Sbjct 145 HPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 204
Query 63 RNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLTA 122
++I YRDLKPENILLD G++K+ DFG AK + YTL GTP Y+APEV+ K Y +
Sbjct 205 KDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSV 264
Query 123 DTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCRL 182
D W+FGV +YE + G PF N + + + +IL +L FP + DA +L+K+L+ R
Sbjct 265 DWWSFGVLIYEMLAGYTPFYNS--NTMKTYENILNAELKFPPFF-HPDAQDLLKKLITRD 321
Query 183 PEVRIGCSINGYKDIKEHAFFSDFDWD 209
R+G NG +D+K H +F++ W+
Sbjct 322 LSERLGNLQNGSEDVKNHPWFNEVIWE 348
> dre:566430 cGMP dependent protein kinase I
Length=528
Score = 179 bits (454), Expect = 6e-45, Method: Compositional matrix adjust.
Identities = 93/209 (44%), Positives = 130/209 (62%), Gaps = 7/209 (3%)
Query 5 FIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHERN 64
FI+RL RTF+D +LY L E GGEL+ +R G +FY A +V A YLH +
Sbjct 277 FIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKG 336
Query 65 IAYRDLKPENILLDSQGYVKLIDFGCAKKM--QGRAYTLVGTPHYMAPEVILGKGYTLTA 122
I YRDLKPEN++LD +GY KL+DFG AKK+ + +T GTP Y+APE+IL KG+ ++A
Sbjct 337 IIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISA 396
Query 123 DTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLM--FPHYVTDQDAINLMKRLLC 180
D W+ G+ +YE + G PF D + + IL G M FP +T ++A NL+K+L
Sbjct 397 DYWSLGILMYELLTGSPPFS--GPDPMKTYNIILRGIDMIEFPKKIT-KNAGNLIKKLCR 453
Query 181 RLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
P R+G NG KDI++H +F F+W+
Sbjct 454 DNPSERLGNLKNGVKDIQKHKWFEGFNWE 482
> tgo:TGME49_028420 cAMP-dependent protein kinase catalytic subunit,
putative (EC:2.7.11.11); K04345 protein kinase A [EC:2.7.11.11]
Length=333
Score = 179 bits (453), Expect = 8e-45, Method: Compositional matrix adjust.
Identities = 98/202 (48%), Positives = 126/202 (62%), Gaps = 3/202 (1%)
Query 2 DHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLH 61
DHP +R +F+D +LY + ELV GGE + +RK A+FY A IV +YLH
Sbjct 82 DHPLTVRCFGSFQDSRYLYLVMELVPGGEFFTHLRKAKRFDNDTARFYAAQIVDIFDYLH 141
Query 62 ERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLT 121
+NI YRDLKPEN+LLD GYVKL DFG AK ++ R TL GTP Y+APEV+L KG+
Sbjct 142 SQNIIYRDLKPENMLLDKDGYVKLTDFGFAKVVEFRTDTLCGTPEYIAPEVLLNKGHGKP 201
Query 122 ADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCR 181
D W G+ +YE M G PF +D D L I++ ILAGK +FP + D+DA L+K+LL
Sbjct 202 VDWWTLGILIYEMMVGYPPFLDD--DPLGIYQKILAGKFVFPKFF-DKDAKVLVKKLLQA 258
Query 182 LPEVRIGCSINGYKDIKEHAFF 203
R G NG +DIKE +F
Sbjct 259 DLSKRWGNLKNGVRDIKECRWF 280
> mmu:19091 Prkg1, AW125416, CGKI, MGC132849, Prkg1b, Prkgr1b;
protein kinase, cGMP-dependent, type I (EC:2.7.11.12); K07376
protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=671
Score = 178 bits (452), Expect = 1e-44, Method: Compositional matrix adjust.
Identities = 92/209 (44%), Positives = 129/209 (61%), Gaps = 7/209 (3%)
Query 5 FIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHERN 64
FI+RL RTF+D +LY L E GGEL+ +R G +FY A +V A YLH +
Sbjct 420 FIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKG 479
Query 65 IAYRDLKPENILLDSQGYVKLIDFGCAKKM--QGRAYTLVGTPHYMAPEVILGKGYTLTA 122
I YRDLKPEN++LD +GY KL+DFG AKK+ + +T GTP Y+APE+IL KG+ ++A
Sbjct 480 IIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISA 539
Query 123 DTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLM--FPHYVTDQDAINLMKRLLC 180
D W+ G+ +YE + G PF D + + IL G M FP + ++A NL+K+L
Sbjct 540 DYWSLGILMYELLTGSPPFS--GPDPMKTYNIILRGIDMIEFPKKIA-KNAANLIKKLCR 596
Query 181 RLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
P R+G NG KDI++H +F F+W+
Sbjct 597 DNPSERLGNLKNGVKDIQKHKWFEGFNWE 625
> hsa:5592 PRKG1, CGKI, DKFZp686K042, FLJ36117, MGC71944, PGK,
PKG, PRKG1B, PRKGR1B, cGKI-BETA, cGKI-alpha; protein kinase,
cGMP-dependent, type I (EC:2.7.11.12); K07376 protein kinase,
cGMP-dependent [EC:2.7.11.12]
Length=671
Score = 178 bits (452), Expect = 1e-44, Method: Compositional matrix adjust.
Identities = 92/209 (44%), Positives = 129/209 (61%), Gaps = 7/209 (3%)
Query 5 FIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHERN 64
FI+RL RTF+D +LY L E GGEL+ +R G +FY A +V A YLH +
Sbjct 420 FIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKG 479
Query 65 IAYRDLKPENILLDSQGYVKLIDFGCAKKM--QGRAYTLVGTPHYMAPEVILGKGYTLTA 122
I YRDLKPEN++LD +GY KL+DFG AKK+ + +T GTP Y+APE+IL KG+ ++A
Sbjct 480 IIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISA 539
Query 123 DTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLM--FPHYVTDQDAINLMKRLLC 180
D W+ G+ +YE + G PF D + + IL G M FP + ++A NL+K+L
Sbjct 540 DYWSLGILMYELLTGSPPFS--GPDPMKTYNIILRGIDMIEFPKKIA-KNAANLIKKLCR 596
Query 181 RLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
P R+G NG KDI++H +F F+W+
Sbjct 597 DNPSERLGNLKNGVKDIQKHKWFEGFNWE 625
> sce:YPL203W TPK2, PKA2, PKA3, YKR1; Tpk2p (EC:2.7.11.11); K04345
protein kinase A [EC:2.7.11.11]
Length=380
Score = 178 bits (451), Expect = 2e-44, Method: Compositional matrix adjust.
Identities = 88/208 (42%), Positives = 130/208 (62%), Gaps = 3/208 (1%)
Query 2 DHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLH 61
+HPF+IR+ TF+D ++ + + + GGEL+ +RK A+FY A ++LA+EYLH
Sbjct 126 EHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLH 185
Query 62 ERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLT 121
NI YRDLKPENILLD G++K+ DFG AK++Q +TL GTP Y+APEVI K Y +
Sbjct 186 AHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTKPYNKS 245
Query 122 ADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCR 181
D W+ GV +YE + G PF + + + IL GK+++P Y D ++L+ +L+
Sbjct 246 VDWWSLGVLIYEMLAGYTPFYDTTP--MKTYEKILQGKVVYPPYF-HPDVVDLLSKLITA 302
Query 182 LPEVRIGCSINGYKDIKEHAFFSDFDWD 209
RIG +G +DIK H +FS+ W+
Sbjct 303 DLTRRIGNLQSGSRDIKAHPWFSEVVWE 330
> xla:444025 prkg2, MGC82580; protein kinase, cGMP-dependent,
type II (EC:2.7.11.1); K07376 protein kinase, cGMP-dependent
[EC:2.7.11.12]
Length=783
Score = 176 bits (446), Expect = 5e-44, Method: Compositional matrix adjust.
Identities = 92/210 (43%), Positives = 132/210 (62%), Gaps = 7/210 (3%)
Query 4 PFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHER 63
PFI++L TF+D ++Y L E GGEL+ +R G A+F + A+EYLH+
Sbjct 532 PFIVKLYCTFKDNKYVYMLLEACLGGELWSILRDRGSFDETTAKFCTGCVTEALEYLHQI 591
Query 64 NIAYRDLKPENILLDSQGYVKLIDFGCAKKM--QGRAYTLVGTPHYMAPEVILGKGYTLT 121
+ YRDLKPEN+LLDS+GYVKL+DFG AKK+ + +T GTP Y+APEVIL KG++ +
Sbjct 592 GVLYRDLKPENLLLDSEGYVKLVDFGFAKKVFPGQKTWTFCGTPEYVAPEVILNKGHSFS 651
Query 122 ADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAG--KLMFPHYVTDQDAINLMKRLL 179
D W+ G+ LYE + G PF DQ++I+ IL G K+ F +T + +L+ RL
Sbjct 652 VDFWSLGILLYELLTGNPPF--TGPDQMIIYNLILQGIEKIEFCKNITKRPE-DLICRLC 708
Query 180 CRLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
+ P R+G NG DIK+H +F+ F+W+
Sbjct 709 RQNPAERLGYMKNGIADIKKHRWFNGFNWE 738
> sce:YJL164C TPK1, PKA1, SRA3; Tpk1p (EC:2.7.11.11); K04345 protein
kinase A [EC:2.7.11.11]
Length=397
Score = 175 bits (443), Expect = 1e-43, Method: Compositional matrix adjust.
Identities = 86/207 (41%), Positives = 128/207 (61%), Gaps = 3/207 (1%)
Query 3 HPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHE 62
HPFIIR+ TF+D ++ + + + GGEL+ +RK A+FY A + LA+EYLH
Sbjct 144 HPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 203
Query 63 RNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLTA 122
++I YRDLKPENILLD G++K+ DFG AK + YTL GTP Y+APEV+ K Y +
Sbjct 204 KDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSI 263
Query 123 DTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCRL 182
D W+FG+ +YE + G PF + + + + IL +L FP + ++D +L+ RL+ R
Sbjct 264 DWWSFGILIYEMLAGYTPFYDS--NTMKTYEKILNAELRFPPFF-NEDVKDLLSRLITRD 320
Query 183 PEVRIGCSINGYKDIKEHAFFSDFDWD 209
R+G NG +D+K H +F + W+
Sbjct 321 LSQRLGNLQNGTEDVKNHPWFKEVVWE 347
> pfa:PFI1685w PfPKAc, PfPKA, PKA; cAMP-dependent protein kinase
catalytic subunit; K04345 protein kinase A [EC:2.7.11.11]
Length=342
Score = 174 bits (442), Expect = 1e-43, Method: Compositional matrix adjust.
Identities = 89/207 (42%), Positives = 126/207 (60%), Gaps = 3/207 (1%)
Query 2 DHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLH 61
+HPF + L +F+D +LY + E V GGE + +R+ FY A IVL EYL
Sbjct 91 NHPFCVNLHGSFKDDSYLYLVLEFVIGGEFFTFLRRNKRFPNDVGCFYAAQIVLIFEYLQ 150
Query 62 ERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLT 121
NI YRDLKPEN+LLD G++K+ DFG AK ++ R YTL GTP Y+APE++L G+
Sbjct 151 SLNIVYRDLKPENLLLDKDGFIKMTDFGFAKIVETRTYTLCGTPEYIAPEILLNVGHGKA 210
Query 122 ADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCR 181
AD W G+ +YE + G PF A + L+I++ IL G + FP ++ D + +LMK+LL
Sbjct 211 ADWWTLGIFIYEILVGCPPFY--ANEPLLIYQKILEGIIYFPKFL-DNNCKHLMKKLLSH 267
Query 182 LPEVRIGCSINGYKDIKEHAFFSDFDW 208
R G G +++KEH +FS+ DW
Sbjct 268 DLTKRYGNLKKGAQNVKEHPWFSNIDW 294
> hsa:5593 PRKG2, PRKGR2, cGKII; protein kinase, cGMP-dependent,
type II (EC:2.7.11.12); K07376 protein kinase, cGMP-dependent
[EC:2.7.11.12]
Length=762
Score = 174 bits (442), Expect = 2e-43, Method: Compositional matrix adjust.
Identities = 88/210 (41%), Positives = 132/210 (62%), Gaps = 7/210 (3%)
Query 4 PFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHER 63
PFI++L RTF+D ++Y L E GGEL+ +R G ++F +A + A +YLH
Sbjct 511 PFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRL 570
Query 64 NIAYRDLKPENILLDSQGYVKLIDFGCAKKMQG--RAYTLVGTPHYMAPEVILGKGYTLT 121
I YRDLKPEN++LD++GY+KL+DFG AKK+ + +T GTP Y+APEVIL KG+ +
Sbjct 571 GIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFS 630
Query 122 ADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAG--KLMFPHYVTDQDAINLMKRLL 179
D W+ G+ +YE + G PF DQ++ + IL G K+ FP +T + +L++RL
Sbjct 631 VDFWSLGILVYELLTGNPPFS--GVDQMMTYNLILKGIEKMDFPRKITRRPE-DLIRRLC 687
Query 180 CRLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
+ P R+G NG DIK+H + + F+W+
Sbjct 688 RQNPTERLGNLKNGINDIKKHRWLNGFNWE 717
> cel:F55A8.2 egl-4; EGg Laying defective family member (egl-4);
K07376 protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=780
Score = 174 bits (441), Expect = 2e-43, Method: Compositional matrix adjust.
Identities = 90/209 (43%), Positives = 128/209 (61%), Gaps = 6/209 (2%)
Query 5 FIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHERN 64
+I++L +TFRD+ F+Y L E+ GGEL+ +R G Y A+FY+A ++ +EYLH +N
Sbjct 529 WIVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKN 588
Query 65 IAYRDLKPENILLDSQGYVKLIDFGCAKKMQG--RAYTLVGTPHYMAPEVILGKGYTLTA 122
I YRDLKPEN LL + GY+KL+DFG AKK+ + +T GTP Y++PE+IL KG+ A
Sbjct 589 IVYRDLKPENCLLANTGYLKLVDFGFAKKLASGRKTWTFCGTPEYVSPEIILNKGHDQAA 648
Query 123 DTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAG--KLMFPHYVTDQDAINLMKRLLC 180
D WA G+ + E M G PF A D + + IL G L P+ + A L+K+L
Sbjct 649 DYWALGIYICELMLGRPPF--QASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKLCR 706
Query 181 RLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
P R+G G DI++H +F FDW+
Sbjct 707 DNPGERLGSGSGGVNDIRKHRWFMGFDWE 735
> hsa:6197 RPS6KA3, CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK,
RSK2, S6K-alpha3, p90-RSK2, pp90RSK2; ribosomal protein S6 kinase,
90kDa, polypeptide 3 (EC:2.7.11.1); K04373 p90 ribosomal
S6 kinase [EC:2.7.11.1]
Length=740
Score = 174 bits (440), Expect = 2e-43, Method: Compositional matrix adjust.
Identities = 86/212 (40%), Positives = 136/212 (64%), Gaps = 8/212 (3%)
Query 2 DHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLH 61
+HPFI++L F+ + LY + + + GG+L+ + K + +FYLA + LA+++LH
Sbjct 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185
Query 62 ERNIAYRDLKPENILLDSQGYVKLIDFGCAKKM---QGRAYTLVGTPHYMAPEVILGKGY 118
I YRDLKPENILLD +G++KL DFG +K+ + +AY+ GT YMAPEV+ +G+
Sbjct 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 245
Query 119 TLTADTWAFGVCLYEFMCGPLPF-GNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKR 177
T +AD W+FGV ++E + G LPF G D ++ + + IL KL P +++ + A +L++
Sbjct 246 TQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTM---ILKAKLGMPQFLSPE-AQSLLRM 301
Query 178 LLCRLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
L R P R+G +G ++IK H+FFS DW+
Sbjct 302 LFKRNPANRLGAGPDGVEEIKRHSFFSTIDWN 333
Score = 106 bits (265), Expect = 5e-23, Method: Compositional matrix adjust.
Identities = 68/201 (33%), Positives = 106/201 (52%), Gaps = 13/201 (6%)
Query 3 HPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHE 62
HP II L + D ++Y +TEL+ GGEL D I + +A L +I +EYLH
Sbjct 473 HPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHA 532
Query 63 RNIAYRDLKPENIL-LDSQG---YVKLIDFGCAKKMQGRAYTLVG---TPHYMAPEVILG 115
+ + +RDLKP NIL +D G +++ DFG AK+++ L+ T +++APEV+
Sbjct 533 QGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKR 592
Query 116 KGYTLTADTWAFGVCLYEFMCGPLPFGNDAEDQL-VIFRDILAGKLMFP----HYVTDQD 170
+GY D W+ GV LY + G PF N +D I I +GK + V+D
Sbjct 593 QGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDT- 651
Query 171 AINLMKRLLCRLPEVRIGCSI 191
A +L+ ++L P R+ ++
Sbjct 652 AKDLVSKMLHVDPHQRLTAAL 672
> mmu:110651 Rps6ka3, MPK-9, Rsk2, S6K-alpha3, pp90RSK2; ribosomal
protein S6 kinase polypeptide 3 (EC:2.7.11.1); K04373 p90
ribosomal S6 kinase [EC:2.7.11.1]
Length=740
Score = 174 bits (440), Expect = 2e-43, Method: Compositional matrix adjust.
Identities = 86/212 (40%), Positives = 136/212 (64%), Gaps = 8/212 (3%)
Query 2 DHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLH 61
+HPFI++L F+ + LY + + + GG+L+ + K + +FYLA + LA+++LH
Sbjct 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185
Query 62 ERNIAYRDLKPENILLDSQGYVKLIDFGCAKKM---QGRAYTLVGTPHYMAPEVILGKGY 118
I YRDLKPENILLD +G++KL DFG +K+ + +AY+ GT YMAPEV+ +G+
Sbjct 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 245
Query 119 TLTADTWAFGVCLYEFMCGPLPF-GNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKR 177
T +AD W+FGV ++E + G LPF G D ++ + + IL KL P +++ + A +L++
Sbjct 246 TQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTM---ILKAKLGMPQFLSPE-AQSLLRM 301
Query 178 LLCRLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
L R P R+G +G ++IK H+FFS DW+
Sbjct 302 LFKRNPANRLGAGPDGVEEIKRHSFFSTIDWN 333
Score = 106 bits (265), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 68/201 (33%), Positives = 106/201 (52%), Gaps = 13/201 (6%)
Query 3 HPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHE 62
HP II L + D ++Y +TEL+ GGEL D I + +A L +I +EYLH
Sbjct 473 HPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHA 532
Query 63 RNIAYRDLKPENIL-LDSQG---YVKLIDFGCAKKMQGRAYTLVG---TPHYMAPEVILG 115
+ + +RDLKP NIL +D G +++ DFG AK+++ L+ T +++APEV+
Sbjct 533 QGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKR 592
Query 116 KGYTLTADTWAFGVCLYEFMCGPLPFGNDAEDQL-VIFRDILAGKLMFP----HYVTDQD 170
+GY D W+ GV LY + G PF N +D I I +GK + V+D
Sbjct 593 QGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDT- 651
Query 171 AINLMKRLLCRLPEVRIGCSI 191
A +L+ ++L P R+ ++
Sbjct 652 AKDLVSKMLHVDPHQRLTAAL 672
> bbo:BBOV_III005740 17.m07511; protein kinase domain containing
protein; K04345 protein kinase A [EC:2.7.11.11]
Length=359
Score = 173 bits (439), Expect = 3e-43, Method: Compositional matrix adjust.
Identities = 92/208 (44%), Positives = 126/208 (60%), Gaps = 3/208 (1%)
Query 2 DHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLH 61
+HPFI+ ++ TF+D +LY + E V GG+ + +R + L A FY A I +Y+H
Sbjct 108 NHPFIVNMLGTFKDPHYLYIVMECVFGGDFFGYLRSVDKLESESAMFYAAQITCIFDYMH 167
Query 62 ERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLT 121
NI YRDLKPEN+L+ S GY+KL DFG AK ++ R YTL GTP Y+APE++L KG+
Sbjct 168 SHNIIYRDLKPENLLVGSDGYLKLTDFGFAKVVELRTYTLCGTPEYLAPEILLNKGHGKA 227
Query 122 ADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCR 181
D W G+ +YE + G PF N ED + I++ IL +L+FP D DA L K+LL
Sbjct 228 VDWWTLGILIYEMLVGYPPFYN--EDPMGIYKKILDCRLVFPRNY-DPDAKALTKQLLTF 284
Query 182 LPEVRIGCSINGYKDIKEHAFFSDFDWD 209
P RIG G KDI +F+ D+D
Sbjct 285 DPSKRIGNLHKGAKDIIASQWFAKMDFD 312
> mmu:19092 Prkg2, AW212535, CGKII, MGC130517, Prkgr2, cGK-II;
protein kinase, cGMP-dependent, type II (EC:2.7.11.12); K07376
protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=762
Score = 172 bits (437), Expect = 5e-43, Method: Compositional matrix adjust.
Identities = 88/210 (41%), Positives = 131/210 (62%), Gaps = 7/210 (3%)
Query 4 PFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHER 63
PFI++L RTF+D ++Y L E GGEL+ +R G ++F +A + A +YLH
Sbjct 511 PFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRL 570
Query 64 NIAYRDLKPENILLDSQGYVKLIDFGCAKKMQG--RAYTLVGTPHYMAPEVILGKGYTLT 121
I YRDLKPEN++LD+ GY+KL+DFG AKK+ + +T GTP Y+APEVIL KG+ +
Sbjct 571 GIIYRDLKPENLILDADGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFS 630
Query 122 ADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAG--KLMFPHYVTDQDAINLMKRLL 179
D W+ G+ +YE + G PF DQ++ + IL G K+ FP +T + +L++RL
Sbjct 631 VDFWSLGILVYELLTGNPPFS--GIDQMMTYNLILKGIEKMDFPRKITRRPE-DLIRRLC 687
Query 180 CRLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
+ P R+G NG DIK+H + + F+W+
Sbjct 688 RQNPTERLGNLKNGINDIKKHRWLNGFNWE 717
> pfa:PFL2250c PKB; rac-beta serine/threonine protein kinase,
PfPKB (EC:2.7.1.-); K08286 protein-serine/threonine kinase [EC:2.7.11.-]
Length=735
Score = 172 bits (435), Expect = 1e-42, Method: Composition-based stats.
Identities = 85/210 (40%), Positives = 129/210 (61%), Gaps = 6/210 (2%)
Query 3 HPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHE 62
HPFI+++ F+ K LYF+ E GGEL+ + KL A+FY + I+LA+EYLH+
Sbjct 460 HPFIVKMYYAFQTKQKLYFILEYCPGGELFFHLSKLREFSEETAKFYSSEIILALEYLHD 519
Query 63 RNIAYRDLKPENILLDSQGYVKLIDFGCAKK---MQGRAYTLVGTPHYMAPEVILGKGYT 119
NI YRDLKPEN+LLD G+++L DFG +K+ +L GTP Y+APE+I KG+
Sbjct 520 LNIIYRDLKPENVLLDELGHIRLTDFGLSKEGITETNLTKSLCGTPEYLAPEIIEQKGHG 579
Query 120 LTADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLL 179
D W+ G+ LYE + G LPF N + V+F I KL +P ++ + A++L+ +L
Sbjct 580 KAVDWWSLGIMLYEMLTGELPFNNTNRN--VLFESIKYQKLNYPKNLSPK-AVDLLTKLF 636
Query 180 CRLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
+ P+ R+G ++IK+H FF + +W+
Sbjct 637 EKNPKKRLGSGGTDAQEIKKHPFFKNINWN 666
> cel:F47F2.1 hypothetical protein; K04345 protein kinase A [EC:2.7.11.11]
Length=398
Score = 172 bits (435), Expect = 1e-42, Method: Compositional matrix adjust.
Identities = 83/207 (40%), Positives = 124/207 (59%), Gaps = 3/207 (1%)
Query 3 HPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHE 62
HPFI+++ + +D + LY + E V GGE++ +R A+FY + IV A+EY+H
Sbjct 147 HPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMARFYASEIVCALEYIHS 206
Query 63 RNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLTA 122
I YRDLKPEN++L +G++K+ DFG AK+++ R YT+ GTP Y+APE + G+
Sbjct 207 LGIVYRDLKPENLMLSKEGHIKMADFGFAKELRDRTYTICGTPDYLAPESLARTGHNKGV 266
Query 123 DTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCRL 182
D WA G+ +YE M G PF + I+ I+ KL FP + A +L+K+LL
Sbjct 267 DWWALGILIYEMMVGKPPFRGKTTSE--IYDAIIEHKLKFPRSF-NLAAKDLVKKLLEVD 323
Query 183 PEVRIGCSINGYKDIKEHAFFSDFDWD 209
RIGC NG +D+K+H +F +WD
Sbjct 324 RTQRIGCMKNGTQDVKDHKWFEKVNWD 350
> sce:YHR205W SCH9, HRM2, KOM1; Protein kinase involved in transcriptional
activation of osmostress-responsive genes; regulates
G1 progression, cAPK activity, nitrogen activation of
the FGM pathway; involved in life span regulation; homologous
to mammalian Akt/PKB (EC:2.7.11.1); K08286 protein-serine/threonine
kinase [EC:2.7.11.-]
Length=824
Score = 171 bits (433), Expect = 2e-42, Method: Composition-based stats.
Identities = 87/208 (41%), Positives = 135/208 (64%), Gaps = 5/208 (2%)
Query 4 PFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHER 63
PFI+ L +F+ LY +T+ ++GGEL+ ++K G +A+FY+A +VLA+E+LH+
Sbjct 473 PFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDN 532
Query 64 NIAYRDLKPENILLDSQGYVKLIDFGCAK-KMQGRAYTLVGTPHYMAPEVILGK-GYTLT 121
+I YRDLKPENILLD+ G + L DFG +K ++ R T GT Y+APE++L + GYT
Sbjct 533 DIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLLDETGYTKM 592
Query 122 ADTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRLLCR 181
D W+ GV ++E CG PF AE+ +++ I GK+ FP V Q+ + +K LL R
Sbjct 593 VDFWSLGVLIFEMCCGWSPFF--AENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNR 650
Query 182 LPEVRIGCSINGYKDIKEHAFFSDFDWD 209
P+ R+G +I+ ++++ H FF+D DW+
Sbjct 651 NPKHRLG-AIDDGRELRAHPFFADIDWE 677
> hsa:6196 RPS6KA2, HU-2, MAPKAPK1C, RSK, RSK3, S6K-alpha, S6K-alpha2,
p90-RSK3, pp90RSK3; ribosomal protein S6 kinase, 90kDa,
polypeptide 2 (EC:2.7.11.1); K04373 p90 ribosomal S6 kinase
[EC:2.7.11.1]
Length=741
Score = 170 bits (431), Expect = 3e-42, Method: Compositional matrix adjust.
Identities = 86/212 (40%), Positives = 134/212 (63%), Gaps = 8/212 (3%)
Query 2 DHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLH 61
+HPFI++L F+ + LY + + + GG+L+ + K + +FYLA + LA+++LH
Sbjct 125 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 184
Query 62 ERNIAYRDLKPENILLDSQGYVKLIDFGCAKKM---QGRAYTLVGTPHYMAPEVILGKGY 118
I YRDLKPENILLD +G++K+ DFG +K+ RAY+ GT YMAPEV+ +G+
Sbjct 185 SLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGH 244
Query 119 TLTADTWAFGVCLYEFMCGPLPF-GNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKR 177
T +AD W+FGV ++E + G LPF G D ++ + + IL KL P +++ + A +L++
Sbjct 245 TQSADWWSFGVLMFEMLTGSLPFQGKDRKETMAL---ILKAKLGMPQFLSGE-AQSLLRA 300
Query 178 LLCRLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
L R P R+G I+G ++IK H FF DW+
Sbjct 301 LFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWN 332
Score = 99.8 bits (247), Expect = 6e-21, Method: Compositional matrix adjust.
Identities = 56/152 (36%), Positives = 83/152 (54%), Gaps = 7/152 (4%)
Query 3 HPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHE 62
HP II L + D F+Y + EL+ GGEL D I + +A L +I ++YLH
Sbjct 474 HPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHS 533
Query 63 RNIAYRDLKPENILL-DSQG---YVKLIDFGCAKKMQ---GRAYTLVGTPHYMAPEVILG 115
+ + +RDLKP NIL D G +++ DFG AK+++ G T T +++APEV+
Sbjct 534 QGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKR 593
Query 116 KGYTLTADTWAFGVCLYEFMCGPLPFGNDAED 147
+GY D W+ G+ LY + G PF N +D
Sbjct 594 QGYDAACDIWSLGILLYTMLAGFTPFANGPDD 625
> cel:T01H8.1 rskn-1; RSK-pNinety (RSK-p90 kinase) homolog family
member (rskn-1); K04373 p90 ribosomal S6 kinase [EC:2.7.11.1]
Length=804
Score = 170 bits (431), Expect = 3e-42, Method: Compositional matrix adjust.
Identities = 86/210 (40%), Positives = 132/210 (62%), Gaps = 8/210 (3%)
Query 3 HPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHE 62
HPFI++L F+ + LY + + + GG+L+ + K + +FYLA + LA+E+LH
Sbjct 157 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHS 216
Query 63 RNIAYRDLKPENILLDSQGYVKLIDFGCAKKM---QGRAYTLVGTPHYMAPEVILGKGYT 119
I YRDLKPENILLD+ G++K+ DFG +K+ + + Y+ GT YMAPEVI +G++
Sbjct 217 LGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHS 276
Query 120 LTADTWAFGVCLYEFMCGPLPF-GNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKRL 178
+ AD W+ GV ++E + G LPF G D D + IL KL PH++T Q+A +L++ L
Sbjct 277 MAADFWSLGVLMFEMLTGHLPFQGRDRNDTMT---QILKAKLSMPHFLT-QEAQSLLRAL 332
Query 179 LCRLPEVRIGCSINGYKDIKEHAFFSDFDW 208
R + R+G +G ++IK HAFF+ D+
Sbjct 333 FKRNSQNRLGAGPDGVEEIKRHAFFAKIDF 362
Score = 102 bits (253), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 63/199 (31%), Positives = 105/199 (52%), Gaps = 16/199 (8%)
Query 3 HPFIIRLVRTFRDKDFLYFLTELVTGGELYDA-IRKLGLLGRYQAQFYLASIVLAIEYLH 61
H F+++L + D+ +Y + EL GGEL D + K L + +A+++ A++YLH
Sbjct 499 HQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLH 558
Query 62 ERNIAYRDLKPENILL----DSQGYVKLIDFGCAKKMQ---GRAYTLVGTPHYMAPEVIL 114
+ +A+RDL NIL ++++DFG AK+ + G T T ++APEV+
Sbjct 559 SQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLR 618
Query 115 GKGYTLTADTWAFGVCLYEFMCGPLPFG---NDAEDQLVIFRDILAGKLMFPHYVTD--- 168
+GY + D W+ GV L+ + G PF ND DQ I + + GK+ H V D
Sbjct 619 KQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQ--ILQRVGDGKISMTHPVWDTIS 676
Query 169 QDAINLMKRLLCRLPEVRI 187
+A +L++++L P R+
Sbjct 677 DEAKDLVRKMLDVDPNRRV 695
> xla:399376 rps6ka3, MGC82193, S6KII, p90, rsk, rsk2; ribosomal
protein S6 kinase, 90kDa, polypeptide 3 (EC:2.7.11.1); K04373
p90 ribosomal S6 kinase [EC:2.7.11.1]
Length=737
Score = 170 bits (430), Expect = 3e-42, Method: Compositional matrix adjust.
Identities = 85/212 (40%), Positives = 134/212 (63%), Gaps = 8/212 (3%)
Query 2 DHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLH 61
+HPFI++L F+ + LY + + + GG+L+ + K + ++YLA + LA+++LH
Sbjct 123 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKYYLAELALALDHLH 182
Query 62 ERNIAYRDLKPENILLDSQGYVKLIDFGCAKKM---QGRAYTLVGTPHYMAPEVILGKGY 118
I YRDLKPENILLD +G++KL DFG +K+ + +AY+ GT YMAPEV+ +G+
Sbjct 183 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 242
Query 119 TLTADTWAFGVCLYEFMCGPLPF-GNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKR 177
T +AD W+FGV ++E + G LPF G D ++ + + IL KL P ++T + A +L++
Sbjct 243 TQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTM---ILKAKLGMPQFLTPE-AQSLLRM 298
Query 178 LLCRLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
L R P R+G +G ++IK H FF DW+
Sbjct 299 LFKRNPTNRLGAGPDGVEEIKRHPFFVTIDWN 330
Score = 105 bits (262), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 58/152 (38%), Positives = 84/152 (55%), Gaps = 7/152 (4%)
Query 3 HPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHE 62
HP II L + D ++Y +TEL+ GGEL D I + +A L +I EYLH
Sbjct 469 HPNIITLKDVYDDGKYVYLVTELMKGGELLDKILRQKFFSEREASAVLHTITKTAEYLHS 528
Query 63 RNIAYRDLKPENIL-LDSQG---YVKLIDFGCAKKMQGRAYTLVG---TPHYMAPEVILG 115
+ + +RDLKP NIL +D G +++ DFG AK+++ L+ T +++APEV+
Sbjct 529 QWVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKR 588
Query 116 KGYTLTADTWAFGVCLYEFMCGPLPFGNDAED 147
+GY D W+ GV LY + G PF N ED
Sbjct 589 QGYDAACDIWSLGVLLYTMLTGYTPFANGPED 620
> mmu:20112 Rps6ka2, 90kDa, D17Wsu134e, Rps6ka-rs1, Rsk3, p90rsk,
pp90rsk; ribosomal protein S6 kinase, polypeptide 2 (EC:2.7.11.1);
K04373 p90 ribosomal S6 kinase [EC:2.7.11.1]
Length=733
Score = 169 bits (429), Expect = 5e-42, Method: Compositional matrix adjust.
Identities = 85/212 (40%), Positives = 134/212 (63%), Gaps = 8/212 (3%)
Query 2 DHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLH 61
+HPFI++L F+ + LY + + + GG+L+ + K + +FYLA + LA+++LH
Sbjct 117 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 176
Query 62 ERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQ---GRAYTLVGTPHYMAPEVILGKGY 118
I YRDLKPENILLD +G++K+ DFG +K+ RAY+ GT YMAPEV+ +G+
Sbjct 177 GLGIIYRDLKPENILLDEEGHIKITDFGLSKEATDHDKRAYSFCGTIEYMAPEVVNRRGH 236
Query 119 TLTADTWAFGVCLYEFMCGPLPF-GNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKR 177
T +AD W+FGV ++E + G LPF G D ++ + + IL KL P +++ +A +L++
Sbjct 237 TQSADWWSFGVLMFEMLTGSLPFQGKDRKETMAL---ILKAKLGMPQFLS-AEAQSLLRA 292
Query 178 LLCRLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
L R P R+G ++G ++IK H FF DW+
Sbjct 293 LFKRNPCNRLGAGVDGVEEIKRHPFFVTIDWN 324
Score = 99.8 bits (247), Expect = 6e-21, Method: Compositional matrix adjust.
Identities = 54/152 (35%), Positives = 84/152 (55%), Gaps = 7/152 (4%)
Query 3 HPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHE 62
HP II L + D ++Y + EL+ GGEL D I + +A L +I ++YLH
Sbjct 466 HPNIITLKDVYDDGKYVYLVMELMRGGELLDRILRQRCFSEREASDVLYTIARTMDYLHS 525
Query 63 RNIAYRDLKPENIL-LDSQG---YVKLIDFGCAKKMQGRAYTLVG---TPHYMAPEVILG 115
+ + +RDLKP NIL +D G +++ DFG AK+++ L+ T +++APEV+
Sbjct 526 QGVVHRDLKPSNILYMDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKR 585
Query 116 KGYTLTADTWAFGVCLYEFMCGPLPFGNDAED 147
+GY D W+ G+ LY + G PF N +D
Sbjct 586 QGYDAACDVWSLGILLYTMLAGFTPFANGPDD 617
> dre:556339 protein kinase, cGMP-dependent, type II-like; K07376
protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=730
Score = 169 bits (427), Expect = 7e-42, Method: Compositional matrix adjust.
Identities = 89/210 (42%), Positives = 131/210 (62%), Gaps = 9/210 (4%)
Query 5 FIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHERN 64
FI+RL RTFRD F+Y L E+ GGEL+ +R + A+F ++ A +YLH +
Sbjct 480 FIVRLFRTFRDDKFVYMLLEVCLGGELWSLLRDMSCFDEPTARFCTGCVLEAFDYLHGKG 539
Query 65 IAYRDLKPENILLDSQGYVKLIDFGCAKK--MQGRAYTLVGTPHYMAPEVILGKGYTLTA 122
I YRDLKPEN+LLD++GYVK+ DFG AKK + + +T GTP Y+APEVI+ KG+ A
Sbjct 540 IVYRDLKPENLLLDAEGYVKMADFGFAKKIGLGKKTWTFCGTPEYVAPEVIMNKGHDFGA 599
Query 123 DTWAFGVCLYEFMCGPLPFGNDAEDQLVIFRDILAG--KLMFPHYVTDQDAINLMKRLLC 180
D W+ G+ ++E + G PF D + I+ +L G K+ P ++ + +L++R LC
Sbjct 600 DCWSLGILIFELLIGSPPF--TGSDPIRIYTMVLHGIEKVDIPKRISKRPE-DLIRR-LC 655
Query 181 RL-PEVRIGCSINGYKDIKEHAFFSDFDWD 209
+L P R+G NG DIK+H +F F+W+
Sbjct 656 KLNPAERLGNKKNGIIDIKKHKWFQGFNWE 685
> dre:571285 ribosomal protein S6 kinase, polypeptide 2-like;
K04373 p90 ribosomal S6 kinase [EC:2.7.11.1]
Length=733
Score = 169 bits (427), Expect = 8e-42, Method: Compositional matrix adjust.
Identities = 84/212 (39%), Positives = 133/212 (62%), Gaps = 8/212 (3%)
Query 2 DHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLH 61
+HPFI++L F+ + LY + + + GG+L+ + K + +FYLA + LA+++LH
Sbjct 117 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 176
Query 62 ERNIAYRDLKPENILLDSQGYVKLIDFGCAKKM---QGRAYTLVGTPHYMAPEVILGKGY 118
I YRDLKPENILLD +G++K+ DFG +K+ RAY+ GT YMAPEV+ +G+
Sbjct 177 SLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGH 236
Query 119 TLTADTWAFGVCLYEFMCGPLPF-GNDAEDQLVIFRDILAGKLMFPHYVTDQDAINLMKR 177
T +AD W+FGV ++E + G LPF G D ++ + + IL KL P +++ + +L++
Sbjct 237 TQSADWWSFGVLMFEMLTGSLPFQGKDRKETMAL---ILKAKLGMPQFLSPE-VQSLLRA 292
Query 178 LLCRLPEVRIGCSINGYKDIKEHAFFSDFDWD 209
L R P R+G +G ++IK H FF+ DW+
Sbjct 293 LFKRNPSNRLGAGPDGVEEIKRHIFFATIDWN 324
Lambda K H
0.328 0.147 0.461
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 6494887820
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
Posted date: Sep 17, 2011 11:19 AM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40