bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
164,496 sequences; 82,071,388 total letters
Query= Emax_0528_orf4
Length=295
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_024350 aminopeptidase N, putative (EC:3.4.11.2); K0... 331 2e-90
bbo:BBOV_IV005930 23.m06519; aminopeptidase (EC:3.4.11.2); K01... 296 6e-80
tgo:TGME49_024460 aminopeptidase N, putative (EC:3.4.11.2) 293 4e-79
tpv:TP01_0397 alpha-aminoacylpeptide hydrolase (EC:3.4.11.2); ... 280 4e-75
cpv:cgd8_3430 zincin/aminopeptidase N like metalloprotease ; K... 249 9e-66
ath:AT1G63770 peptidase M1 family protein; K01256 aminopeptida... 246 8e-65
tgo:TGME49_021310 aminopeptidase N, putative (EC:3.4.11.2) 219 1e-56
eco:b0932 pepN, ECK0923, JW0915; aminopeptidase N (EC:3.4.11.2... 207 4e-53
pfa:MAL13P1.56 M1-family aminopeptidase (EC:3.4.11.-); K13725 ... 206 8e-53
mmu:19155 Npepps, AAP-S, MGC102199, MP100, Psa, R74825, goku; ... 62.0 2e-09
hsa:9520 NPEPPS, AAP-S, MP100, PSA; aminopeptidase puromycin s... 60.1 9e-09
dre:407726 npepps, Psa, fb68d07, sb:cb848, wu:fb68d07; aminope... 56.6 1e-07
cel:F49E8.3 pam-1; Puromycin-sensitive AMinopeptidase family m... 55.5 2e-07
dre:562409 thyrotropin-releasing hormone-degrading ectoenzyme-... 54.3 6e-07
dre:504088 enpep, im:7152184, si:ch211-146m5.2; glutamyl amino... 53.1 1e-06
ath:AT4G33090 APM1; APM1 (AMINOPEPTIDASE M1); aminopeptidase; ... 52.0 3e-06
dre:100006808 trh-de, PAP-II; thyrotropin-releasing hormone-de... 52.0 3e-06
sce:YHR047C AAP1, AAP1'; Aap1p (EC:3.4.11.-) 47.8 5e-05
hsa:2028 ENPEP, APA, CD249, gp160; glutamyl aminopeptidase (am... 47.8 6e-05
mmu:13809 Enpep, 6030431M22Rik, APA, Bp-1/6C3, Ly-51, Ly51; gl... 47.0 8e-05
sce:YKL157W APE2, LAP1, YKL158W; Aminopeptidase yscII; may hav... 47.0 8e-05
dre:555317 aminopeptidase N-like 41.6 0.004
cel:T07F10.1 hypothetical protein 40.4 0.009
dre:558452 fd60b03, wu:fd60b03; si:ch211-200o3.4 (EC:3.4.11.2) 38.9 0.022
dre:322533 anpep, fb64c05, wu:fb64c05, zgc:136771; alanyl (mem... 37.7 0.048
mmu:240028 Lnpep, 2010309L07Rik, 4732490P18Rik, CAP, IRAP, PLA... 37.7 0.051
mmu:16790 Anpep, Apn, Cd13, Lap-1, Lap1, P150; alanyl (membran... 36.2 0.16
cel:Y67D8C.9 hypothetical protein 34.7 0.41
cel:R03G8.6 hypothetical protein 34.3 0.51
hsa:64167 ERAP2, FLJ23633, FLJ23701, FLJ23807, L-RAP, LRAP; en... 33.9 0.69
hsa:51752 ERAP1, A-LAP, ALAP, APPILS, ARTS-1, ARTS1, ERAAP, ER... 33.9 0.69
dre:555478 aminopeptidase N-like; K11140 aminopeptidase N [EC:... 33.1 1.1
xla:495476 anpep; alanyl (membrane) aminopeptidase; K11140 ami... 32.7 1.5
hsa:4012 LNPEP, CAP, IRAP, P-LAP, PLAP; leucyl/cystinyl aminop... 32.7 1.8
cel:Y42A5A.1 hypothetical protein 31.6 3.2
mmu:26885 Casp8ap2, AA387232, D4Ertd659e, FLASH, mKIAA1315; ca... 30.0 9.8
> tgo:TGME49_024350 aminopeptidase N, putative (EC:3.4.11.2);
K01256 aminopeptidase N [EC:3.4.11.2]
Length=1419
Score = 331 bits (848), Expect = 2e-90, Method: Compositional matrix adjust.
Identities = 166/297 (55%), Positives = 212/297 (71%), Gaps = 4/297 (1%)
Query 1 LKEGLTVFREQLFMGTFMSAGVQRIKEVADLISRQFPEDDGPMAHAIRPESYLAMDNFYT 60
LKEGLTVFR+QLF SA V+RI++V L SRQF ED GPMAH IRPE+Y+AMDNFYT
Sbjct 856 LKEGLTVFRDQLFTADMCSAAVKRIEDVVFLRSRQFAEDSGPMAHPIRPETYIAMDNFYT 915
Query 61 ATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADANGINLDQMD 120
ATVYDKGAEV+R+Y+TLLG +GFRKGMDLYFKRHD K TCDDFRAAMADANG +L Q +
Sbjct 916 ATVYDKGAEVIRMYHTLLGEAGFRKGMDLYFKRHDGKAVTCDDFRAAMADANGRDLGQFE 975
Query 121 RWYSQAGTPRLEVLRSEYKEDEKAFEISFRQHTPPTRGQETKRPQLIPIKIGLIGRASHQ 180
RWY QAGTP + V + ++ D K F+++ +Q TPPT GQ K P IPIK+GLIG+ S +
Sbjct 976 RWYLQAGTPEVTVSEAVFQPDRKKFKLTLKQRTPPTPGQVEKHPFHIPIKVGLIGKTSKK 1035
Query 181 DLLQPAV-VLEMTEEEQTFRVRGVREDCVPSILRGFSAPVRLINRPQTAKESAFLLAYDT 239
D+L P VLE+TE EQTF + EDCV S LR FSAPV+ + QT ++ AFL+A+D+
Sbjct 1036 DILSPPTKVLELTEAEQTFELDAA-EDCVLSFLRDFSAPVK-VKHEQTDEDIAFLMAHDS 1093
Query 240 DPVTKWFASRALATPIVISRSKRISAK-GNAQKLEQLPDDYVEGLRAIIYDQATDNA 295
D KW A+ LA+ ++ R+++ K G + +LP YVE + + +Q D +
Sbjct 1094 DDFAKWQAAHTLASGLLKHRAEQWREKQGEDVEFARLPKIYVEAFKQTLLEQGRDRS 1150
> bbo:BBOV_IV005930 23.m06519; aminopeptidase (EC:3.4.11.2); K01256
aminopeptidase N [EC:3.4.11.2]
Length=846
Score = 296 bits (758), Expect = 6e-80, Method: Compositional matrix adjust.
Identities = 145/258 (56%), Positives = 187/258 (72%), Gaps = 4/258 (1%)
Query 1 LKEGLTVFREQLFMGTFMSAGVQRIKEVADLISRQFPEDDGPMAHAIRPESYLAMDNFYT 60
LKEGLTVFRE F G S + RI +V +L + QF ED GP+AH IRPESY++MDNFYT
Sbjct 355 LKEGLTVFRESEFAGDMSSPLITRITDVRNLRTYQFAEDAGPLAHPIRPESYISMDNFYT 414
Query 61 ATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADANGINLDQMD 120
TVYDKG+EV+ +Y TLLG GFRKGMDLYF+RHD+ TCDDFRAAMADANG++L Q +
Sbjct 415 TTVYDKGSEVIGMYKTLLGKDGFRKGMDLYFERHDSHAVTCDDFRAAMADANGVDLTQFE 474
Query 121 RWYSQAGTPRLEVLRSEYKEDEKAFEISFRQHTPPTRGQETKRPQLIPIKIGLIGRASHQ 180
RWY QAGTP +EVL E D F + RQ+TPPT QETK P IPIKIGL+G++S +
Sbjct 475 RWYFQAGTPEVEVL--EAVRDGTTFRLRLRQYTPPTPRQETKLPFHIPIKIGLLGKSSKR 532
Query 181 DLLQPAVVLEMTEEEQTFRVRGVREDCVPSILRGFSAPVRLINRPQTAKESAFLLAYDTD 240
D L+ ++VLE+ E EQTF + V EDCV S RGFSAP++ + Q+ ++ FL+++DTD
Sbjct 533 D-LKGSIVLELRESEQTFEINDVNEDCVLSFNRGFSAPIK-VKFQQSDEDLLFLMSHDTD 590
Query 241 PVTKWFASRALATPIVIS 258
+ +W A + + T ++S
Sbjct 591 GLNRWEAGQCMRTKAILS 608
> tgo:TGME49_024460 aminopeptidase N, putative (EC:3.4.11.2)
Length=970
Score = 293 bits (751), Expect = 4e-79, Method: Compositional matrix adjust.
Identities = 146/297 (49%), Positives = 195/297 (65%), Gaps = 10/297 (3%)
Query 1 LKEGLTVFREQLFMGTFMSAGVQRIKEVADLISRQFPEDDGPMAHAIRPESYLAMDNFYT 60
LKEGLT+FR F S ++RI +VAD++S QF ED GP AH IRPE+Y +++N YT
Sbjct 397 LKEGLTMFRNNSFTEETTSRAMKRIGDVADILSIQFREDSGPFAHPIRPETYKSIENLYT 456
Query 61 ATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADANGINLDQMD 120
TVY KGAEV R+Y T+LG GFR+GMDLYFKRHD K TCDD RAAMADAN +L Q +
Sbjct 457 RTVYLKGAEVNRMYRTMLGPKGFRRGMDLYFKRHDGKAVTCDDLRAAMADANDKDLSQFE 516
Query 121 RWYSQAGTPRLEVLRSEYKEDEKAFEISFRQHTPPTRGQETKRPQLIPIKIGLIGRASHQ 180
RWYSQAGTP + V Y E+ ++ +QHTPPT GQ+ K P IP+ +G IG+ S +
Sbjct 517 RWYSQAGTPHVTVSSFIYDAAERKMHLTLKQHTPPTPGQDKKLPLQIPVAVGCIGKTSKR 576
Query 181 DLLQPAV-VLEMTEEEQTFRVRGVREDCVPSILRGFSAPVRLINRPQTAKESAFLLAYDT 239
D+L P +LE+TEEEQ F + V EDCV S+LR FSAPV+LI QT ++ AFL+ YD+
Sbjct 577 DVLSPPTQILELTEEEQAFVLVDVGEDCVLSVLRDFSAPVKLIQPLQTDEDLAFLVTYDS 636
Query 240 DPVTKWFASRALATPIVISRSKRISAK---------GNAQKLEQLPDDYVEGLRAII 287
D V +W A++ L+ ++++R + + +LP YV+ +R I+
Sbjct 637 DNVNRWQAAQTLSRKVLLTRISEYQQRVEEIEEGRVSESDLFSKLPTQYVQTVRDIV 693
> tpv:TP01_0397 alpha-aminoacylpeptide hydrolase (EC:3.4.11.2);
K01256 aminopeptidase N [EC:3.4.11.2]
Length=1020
Score = 280 bits (716), Expect = 4e-75, Method: Compositional matrix adjust.
Identities = 146/287 (50%), Positives = 199/287 (69%), Gaps = 12/287 (4%)
Query 1 LKEGLTVFREQLFMGTFMSAGVQRIKEVADLISRQFPEDDGPMAHAIRPESYLAMDNFYT 60
LKEGLTVFRE F G S RI+EV L+S QFPED GPM+H IRPESY++MDNFYT
Sbjct 477 LKEGLTVFREHQFCGDMSSTLSNRIREVQYLMSVQFPEDSGPMSHPIRPESYISMDNFYT 536
Query 61 ATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADANGINLDQMD 120
TVYDKGA V+ +Y +LLG GFR+GMDLYFKRHD TCDDFR AMADAN +L Q +
Sbjct 537 PTVYDKGAFVIGMYESLLGVDGFRRGMDLYFKRHDLSAVTCDDFRLAMADANNKDLTQFE 596
Query 121 RWYSQAGTPRLEVLRSEYKEDEKAFEISFRQHTPPTRGQETKRPQLIPIKIGLIGRASHQ 180
RWY Q+GTP +EV+R+E +++ +++ RQ TPPT Q K+P IP+++GLIG+++
Sbjct 597 RWYYQSGTPVVEVVRAERVDNK--YKLVLRQSTPPTPKQPVKQPFHIPLRLGLIGKSTGG 654
Query 181 DLLQPAVVLEMTEEEQTFRVRGVREDCVPSILRGFSAPVRLINRPQTAKESAFLLAYDTD 240
DLL V++E+ EE+Q F V EDCV S+ RGFSAPV+ + Q+ +E FL+ YDTD
Sbjct 655 DLLG-NVLVELKEEQQEFEFGPVTEDCVLSLNRGFSAPVK-VKYEQSPEELLFLMLYDTD 712
Query 241 PVTKWFASRALATPIVISRSKRISAKGNAQKLEQLPDDYVEGLRAII 287
+ +W A+++LAT +V+ +K +A ++P Y+E + ++
Sbjct 713 GLNRWNAAQSLATKVVLDLTKDPTA--------EVPKTYLEAYKKLL 751
> cpv:cgd8_3430 zincin/aminopeptidase N like metalloprotease ;
K01256 aminopeptidase N [EC:3.4.11.2]
Length=936
Score = 249 bits (636), Expect = 9e-66, Method: Compositional matrix adjust.
Identities = 128/265 (48%), Positives = 174/265 (65%), Gaps = 2/265 (0%)
Query 1 LKEGLTVFREQLFMGTFMSAGVQRIKEVADLISRQFPEDDGPMAHAIRPESYLAMDNFYT 60
LKEGLTV+R+Q F + +++ ++ L + QF ED GP+AH IRP+S ++ +N YT
Sbjct 357 LKEGLTVYRDQEFSRDCIDRLSEQLGDIEVLRNYQFQEDSGPLAHPIRPDSIVSTNNLYT 416
Query 61 ATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADANGINLDQMD 120
+TVY KGAEVVR+Y T+LG GFRKGMDLYF RHD + TCDDFR AM DAN N Q +
Sbjct 417 STVYRKGAEVVRMYETILGREGFRKGMDLYFARHDGQAVTCDDFRKAMEDANNYNFTQFE 476
Query 121 RWYSQAGTPRLEVLRSEYKEDEKAFEISFRQHTPPTRGQETKRPQLIPIKIGLIGRASHQ 180
RWY QAGTP +EV+ ++ + E I+ RQ PT Q KRP IP+ +GLIG+ S +
Sbjct 477 RWYDQAGTPEVEVVSIDHNKAEGTCSITLRQRCSPTPEQPKKRPFYIPVIVGLIGKDSCK 536
Query 181 DLLQPAVVLEMTEEEQTFRVRGVREDCVPSILRGFSAPVRL-INRPQTAKESAFLLAYDT 239
++ Q ++ + E++QTF + GV E V SILRGFSAPV L P++ +E AFL A+DT
Sbjct 537 EIRQSETLI-LKEQQQTFILDGVWETPVASILRGFSAPVNLRFKTPRSDEELAFLFAFDT 595
Query 240 DPVTKWFASRALATPIVISRSKRIS 264
D ++ A++ L I+I S S
Sbjct 596 DEYNRFDAAQTLYKKILIQASTNSS 620
> ath:AT1G63770 peptidase M1 family protein; K01256 aminopeptidase
N [EC:3.4.11.2]
Length=987
Score = 246 bits (628), Expect = 8e-65, Method: Compositional matrix adjust.
Identities = 135/318 (42%), Positives = 187/318 (58%), Gaps = 31/318 (9%)
Query 1 LKEGLTVFREQLFMGTFMSAGVQRIKEVADLISRQFPEDDGPMAHAIRPESYLAMDNFYT 60
LKEGLTVFR+Q F S V+RI +V+ L QFP+D GPMAH +RP SY+ MDNFYT
Sbjct 414 LKEGLTVFRDQEFSSDMGSRTVKRIADVSKLRIYQFPQDAGPMAHPVRPHSYIKMDNFYT 473
Query 61 ATVYDK------------GAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAM 108
TVY+K GAEVVR+Y TLLG GFRKG+DLYF+RHD + TC+DF AAM
Sbjct 474 VTVYEKVWLFTNSVLLYAGAEVVRMYKTLLGTQGFRKGIDLYFERHDEQAVTCEDFFAAM 533
Query 109 ADANGINLDQMDRWYSQAGTPRLEVLRSEYKEDEKAFEISFRQHTPPTRGQETKRPQLIP 168
DAN + +WYSQAGTP ++V+ S Y D + F + F Q PPT GQ TK P IP
Sbjct 534 RDANNADFANFLQWYSQAGTPVVKVV-SSYNADARTFSLKFSQEIPPTPGQPTKEPTFIP 592
Query 169 IKIGLIGRAS--------HQD-----LLQPAVVLEMTEEEQTFRVRGVREDCVPSILRGF 215
+ +GL+ + H D + + +L +T++E+ F + E VPS+ RGF
Sbjct 593 VVVGLLDSSGKDITLSSVHHDGTVQTISGSSTILRVTKKEEEFVFSDIPERPVPSLFRGF 652
Query 216 SAPVRLINRPQTAKESAFLLAYDTDPVTKWFASRALATPIVISRSKRISAKGNAQKLEQL 275
SAPVR + + + FLLA+D+D +W A + LA ++++ + + K L
Sbjct 653 SAPVR-VETDLSNDDLFFLLAHDSDEFNRWEAGQVLARKLMLN----LVSDFQQNKPLAL 707
Query 276 PDDYVEGLRAIIYDQATD 293
+V+GL +++ D + D
Sbjct 708 NPKFVQGLGSVLSDSSLD 725
> tgo:TGME49_021310 aminopeptidase N, putative (EC:3.4.11.2)
Length=966
Score = 219 bits (557), Expect = 1e-56, Method: Compositional matrix adjust.
Identities = 115/268 (42%), Positives = 166/268 (61%), Gaps = 9/268 (3%)
Query 1 LKEGLTVFREQLFMGTFMSAGVQRIKEVADLISRQFPEDDGPMAHAIRPESYLAMDNFYT 60
LKEGLTV+REQ FMG+ S+GV R+++ ++S+QF ED GP+AH +RP+ Y ++DN Y+
Sbjct 367 LKEGLTVYREQEFMGSQYSSGVARVEDARLVLSQQFREDSGPLAHPVRPDHYASVDNLYS 426
Query 61 ATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADANGINLDQMD 120
TVY KGAE+ R+Y TLLG S FRKG++LYF R+D + ATC++FR+AM +A+G NL Q
Sbjct 427 VTVYKKGAEIFRMYATLLGPSAFRKGLNLYFSRYDGQAATCENFRSAMEEASGRNLSQFF 486
Query 121 RWYSQAGTPRLEVLRSEYKEDEKAFEISFRQHTPPTRGQETK----RPQL--IPIKIGLI 174
WY++ GTP +E+ + + K F + Q PP E + + Q IPI++ I
Sbjct 487 LWYTREGTPEVEITGFTFDKTRKQFSFTVTQKPPPMSDYEIRMYGQKAQFLHIPIRVSFI 546
Query 175 GRASHQDLL---QPAVVLEMTEEEQTFRVRGVREDCVPSILRGFSAPVRLINRPQTAKES 231
R + + L Q VLE+ E QTF E+ + + L+ FSAPV+L QT ++
Sbjct 547 NRRTKKPELYVGQRTTVLELRGETQTFTFTDTEEEPLVAPLQSFSAPVKLTVPSQTEEDL 606
Query 232 AFLLAYDTDPVTKWFASRALATPIVISR 259
A L+ DP T+W A + LA I+ R
Sbjct 607 AILIGASFDPFTRWNAFQFLALQILKER 634
> eco:b0932 pepN, ECK0923, JW0915; aminopeptidase N (EC:3.4.11.2);
K01256 aminopeptidase N [EC:3.4.11.2]
Length=870
Score = 207 bits (527), Expect = 4e-53, Method: Compositional matrix adjust.
Identities = 123/301 (40%), Positives = 171/301 (56%), Gaps = 13/301 (4%)
Query 1 LKEGLTVFREQLFMGTFMSAGVQRIKEVADLISRQFPEDDGPMAHAIRPESYLAMDNFYT 60
LKEGLTVFR+Q F S V RI V + QF ED PMAH IRP+ + M+NFYT
Sbjct 318 LKEGLTVFRDQEFSSDLGSRAVNRINNVRTMRGLQFAEDASPMAHPIRPDMVIEMNNFYT 377
Query 61 ATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADANGINLDQMD 120
TVY+KGAEV+R+ +TLLG F+KGM LYF+RHD ATCDDF AM DA+ ++L
Sbjct 378 LTVYEKGAEVIRMIHTLLGEENFQKGMQLYFERHDGSAATCDDFVQAMEDASNVDLSHFR 437
Query 121 RWYSQAGTPRLEVLRSEYKEDEKAFEISFRQHTPPTRGQETKRPQLIPIKIGLIGRASHQ 180
RWYSQ+GTP + V + +Y + + + ++ Q TP T Q K+P IP I L
Sbjct 438 RWYSQSGTPIVTV-KDDYNPETEQYTLTISQRTPATPDQAEKQPLHIPFAIELYDNEGKV 496
Query 181 DLLQPA-----VVLEMTEEEQTFRVRGVREDCVPSILRGFSAPVRLINRPQTAKESAFLL 235
LQ VL +T+ EQTF V VP++L FSAPV+L + ++ FL+
Sbjct 497 IPLQKGGHPVNSVLNVTQAEQTFVFDNVYFQPVPALLCEFSAPVKL-EYKWSDQQLTFLM 555
Query 236 AYDTDPVTKWFASRA-LATPIVISRSKRISAKGNAQKLEQLPDDYVEGLRAIIYDQATDN 294
+ + ++W A+++ LAT I ++ ++ Q L LP + RA++ D+ D
Sbjct 556 RHARNDFSRWDAAQSLLATYIKLN----VARHQQGQPL-SLPVHVADAFRAVLLDEKIDP 610
Query 295 A 295
A
Sbjct 611 A 611
> pfa:MAL13P1.56 M1-family aminopeptidase (EC:3.4.11.-); K13725
M1-family aminopeptidase [EC:3.4.11.-]
Length=1085
Score = 206 bits (524), Expect = 8e-53, Method: Composition-based stats.
Identities = 107/252 (42%), Positives = 149/252 (59%), Gaps = 10/252 (3%)
Query 1 LKEGLTVFREQLFMGTFMSAGVQRIKEVADLISRQFPEDDGPMAHAIRPESYLAMDNFYT 60
LKEGLTV RE LF R+ V L S QF ED P++H IRPESY++M+NFYT
Sbjct 517 LKEGLTVHRENLFSEEMTKTVTTRLSHVDLLRSVQFLEDSSPLSHPIRPESYVSMENFYT 576
Query 61 ATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADA-------NG 113
TVYDKG+EV+R+Y T+LG ++KG D+Y K++D ATC+DF AM A N
Sbjct 577 TTVYDKGSEVMRMYLTILGEEYYKKGFDIYIKKNDGNTATCEDFNYAMEQAYKMKKADNS 636
Query 114 INLDQMDRWYSQAGTPRLEVLRSEYKEDEKAFEISFRQHTPPTRGQETKRPQLIPIKIGL 173
NL+Q W+SQ+GTP + + Y ++K + I Q+T P Q+ K+P IPI +GL
Sbjct 637 ANLNQYLLWFSQSGTPHVS-FKYNYDAEKKQYSIHVNQYTKPDENQKEKKPLFIPISVGL 695
Query 174 IGRASHQDLLQPAVVLEMTEEEQTFRVRGVREDCVPSILRGFSAPVRLINRPQTAKESAF 233
I + ++++ LE+T+E TF + +PS+ RGFSAPV I T +E
Sbjct 696 INPENGKEMIS-QTTLELTKESDTFVFNNIAVKPIPSLFRGFSAPV-YIEDNLTDEERIL 753
Query 234 LLAYDTDPVTKW 245
LL YD+D ++
Sbjct 754 LLKYDSDAFVRY 765
> mmu:19155 Npepps, AAP-S, MGC102199, MP100, Psa, R74825, goku;
aminopeptidase puromycin sensitive (EC:3.4.11.14); K08776
puromycin-sensitive aminopeptidase [EC:3.4.11.-]
Length=920
Score = 62.0 bits (149), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 52/204 (25%), Positives = 99/204 (48%), Gaps = 20/204 (9%)
Query 7 VFREQLFMGTFMSAGVQRIKEVADLISRQFPEDDGPMAHAIRPESYLAMDNFYTATVYDK 66
F E F+SA R +E+ L ++ P+ ++ S +D + A Y K
Sbjct 390 CFPEYDIWTQFVSADYTRAQELDAL------DNSHPIEVSVGHPS--EVDEIFDAISYSK 441
Query 67 GAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADANGINLDQ-MDRWYSQ 125
GA V+R+ + +G F+KGM++Y + K A +D ++ A+G + M+ W Q
Sbjct 442 GASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLESASGKPIAAVMNTWTKQ 501
Query 126 AGTPRLEVLRSEYKEDEKAFEISFRQH--TPPTRGQETKRPQ-LIPIKIGLIGRASHQDL 182
G P + V +E ED++ ++S ++ + P G++ PQ ++PI I ++ +D
Sbjct 502 MGFPLIYV-EAEQVEDDRVLKLSQKKFCASGPYGGEDC--PQWMVPITI-----STSEDP 553
Query 183 LQPAVVLEMTEEEQTFRVRGVRED 206
Q + + M + E + ++ V+ D
Sbjct 554 NQAKLKILMDKPEMSVVLKNVKPD 577
> hsa:9520 NPEPPS, AAP-S, MP100, PSA; aminopeptidase puromycin
sensitive (EC:3.4.11.14); K08776 puromycin-sensitive aminopeptidase
[EC:3.4.11.-]
Length=919
Score = 60.1 bits (144), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 50/202 (24%), Positives = 93/202 (46%), Gaps = 16/202 (7%)
Query 7 VFREQLFMGTFMSAGVQRIKEVADLISRQFPEDDGPMAHAIRPESYLAMDNFYTATVYDK 66
F E F+SA R +E+ L ++ P+ ++ S +D + A Y K
Sbjct 389 CFPEYDIWTQFVSADYTRAQELDAL------DNSHPIEVSVGHPS--EVDEIFDAISYSK 440
Query 67 GAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADANGINLDQ-MDRWYSQ 125
GA V+R+ + +G F+KGM++Y + K A +D ++ +A+G + M+ W Q
Sbjct 441 GASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLENASGKPIAAVMNTWTKQ 500
Query 126 AGTPRLEVLRSEYKEDEKAFEISFRQHTPPTRGQETKRPQ-LIPIKIGLIGRASHQDLLQ 184
G P + V +E ED++ +S ++ PQ ++PI I ++ +D Q
Sbjct 501 MGFPLIYV-EAEQVEDDRLLRLSQKKFCAGGSYVGEDCPQWMVPITI-----STSEDPNQ 554
Query 185 PAVVLEMTEEEQTFRVRGVRED 206
+ + M + E ++ V+ D
Sbjct 555 AKLKILMDKPEMNVVLKNVKPD 576
> dre:407726 npepps, Psa, fb68d07, sb:cb848, wu:fb68d07; aminopeptidase
puromycin sensitive (EC:3.4.11.-); K08776 puromycin-sensitive
aminopeptidase [EC:3.4.11.-]
Length=872
Score = 56.6 bits (135), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 34/119 (28%), Positives = 59/119 (49%), Gaps = 3/119 (2%)
Query 55 MDNFYTATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADANGI 114
+D + A Y KGA V+R+ + +G FRKGM+ Y + +K A+ +D + A+G
Sbjct 384 VDEIFDAISYSKGASVIRMLHNYIGDEDFRKGMNAYLLKFQHKNASTEDLWECLEQASGK 443
Query 115 NLDQ-MDRWYSQAGTPRLEVLRSEYKEDEKAFEISFRQHTPPT-RGQETKRPQLIPIKI 171
+ M+ W Q G P + V + ++ D + +IS ++ R E ++PI I
Sbjct 444 PIAAVMNSWTKQMGFPIIVVDQEQHGSD-RVLKISQKKFCASGPRNDEDCPNWMVPISI 501
> cel:F49E8.3 pam-1; Puromycin-sensitive AMinopeptidase family
member (pam-1); K08776 puromycin-sensitive aminopeptidase [EC:3.4.11.-]
Length=948
Score = 55.5 bits (132), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 52/206 (25%), Positives = 87/206 (42%), Gaps = 9/206 (4%)
Query 1 LKEGLTVFREQLFMGTFMSAGVQRIKEVADLISRQFPEDDGPMAHAIRPE--SYLAMDNF 58
LKEG F E +F+G + + D ++ D +H I E + +D
Sbjct 398 LKEGFASFMEYMFVGANCPEFKIWLHFLNDELASGMGLDALRNSHPIEVEIDNPNELDEI 457
Query 59 YTATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADANGINLDQ 118
Y + Y K V R+ L F+KG+ LY KR A D A+++A+G N+++
Sbjct 458 YDSITYAKSNSVNRMLCYYLSEPVFQKGLRLYLKRFQYSNAVTQDLWTALSEASGQNVNE 517
Query 119 -MDRWYSQAGTPRLEVLRSEYKEDEKAFEISFRQHTPPTRGQETKRPQLIPIKIGLIGRA 177
M W Q G P VL+ ++D ++ Q + G E + + I + +
Sbjct 518 LMSGWTQQMGFP---VLKVSQRQDGNNRILTVEQRRFISDGGEDPKNSQWQVPITVAVGS 574
Query 178 SHQDLLQPAVVLEMTEEEQTFRVRGV 203
S D+ + E++Q F + GV
Sbjct 575 SPSDV---KARFLLKEKQQEFTIEGV 597
> dre:562409 thyrotropin-releasing hormone-degrading ectoenzyme-like;
K01306 pyroglutamyl-peptidase II [EC:3.4.19.6]
Length=994
Score = 54.3 bits (129), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 52/222 (23%), Positives = 103/222 (46%), Gaps = 28/222 (12%)
Query 1 LKEGLTVFREQLFMGT---FMSAGVQRIKEVADLISRQFPEDDGPMAHAIRPESYLA--M 55
LKEG + E ++GT F +++ + + D++ D +H I + + A +
Sbjct 431 LKEGFAHYFE--YIGTDFLFPKWNMEKQRFLTDVLHEVMLLDGLASSHPISQQVFEATDI 488
Query 56 DNFYTATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADA---- 111
D + Y KGA ++R+ ++G + F++ ++ Y H A DD +++A
Sbjct 489 DRVFDWIAYKKGAALIRMLANVMGQTLFQRALNDYLMTHMYGNAARDDLWNKLSEAMQRE 548
Query 112 -NGINLDQ-MDRWYSQAGTPRLEVLRSEYKEDEKAFEISFRQHTPPTRGQETKRPQL--- 166
IN+ Q MDRW Q G P + + +++ ++ + IS ++H + + P+L
Sbjct 549 GKDINITQVMDRWTLQMGYPVVTISKNDSLDN--SITIS-QEHFVYDTDAKIQNPELFNK 605
Query 167 -----IPIKIGLIGRASHQDLLQPAVVLEMTEEEQTFRVRGV 203
IP+ + +G ASH + ++ +T + + RV V
Sbjct 606 SFQWQIPLTLA-VGNASH---ISTETIIWVTNKSEAHRVGHV 643
> dre:504088 enpep, im:7152184, si:ch211-146m5.2; glutamyl aminopeptidase
(EC:3.4.11.7)
Length=951
Score = 53.1 bits (126), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Query 59 YTATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADANGINL-D 117
+ A Y+KGA ++R+ LLG FR G Y K + + A DF A+AD +G+ + D
Sbjct 465 FDAISYNKGASILRMLEDLLGRETFRDGCRRYLKTYLFQNAKTSDFWKALADESGLPVAD 524
Query 118 QMDRWYSQAGTPRLEVLRSE 137
MD W Q G P L + ++
Sbjct 525 IMDTWTKQMGYPVLSLTNTD 544
> ath:AT4G33090 APM1; APM1 (AMINOPEPTIDASE M1); aminopeptidase;
K08776 puromycin-sensitive aminopeptidase [EC:3.4.11.-]
Length=879
Score = 52.0 bits (123), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 10/119 (8%)
Query 55 MDNFYTATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADANGI 114
+D + A Y KGA V+R+ + LGA F+K + Y K H A +D AA+ +G
Sbjct 383 IDEIFDAISYRKGASVIRMLQSYLGAEVFQKSLAAYIKNHAYSNAKTEDLWAALEAGSGE 442
Query 115 NLDQ-MDRWYSQAGTPRLEVLRSEYKEDEKAFEIS-FRQHTPPTRGQETKRPQLIPIKI 171
+++ M W Q G P V+ ++ K+ + E S F P GQ ++P+ +
Sbjct 443 PVNKLMSSWTKQKGYP---VVSAKIKDGKLELEQSRFLSSGSPGEGQ-----WIVPVTL 493
> dre:100006808 trh-de, PAP-II; thyrotropin-releasing hormone-degrading
ectoenzyme
Length=994
Score = 52.0 bits (123), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 50/219 (22%), Positives = 101/219 (46%), Gaps = 28/219 (12%)
Query 1 LKEGLTVFREQLFMGT---FMSAGVQRIKEVADLISRQFPEDDGPMAHAIRPESYLA--M 55
LKEG + E ++G F +++ + + D++ D +H I + + A +
Sbjct 431 LKEGFAHYFE--YIGADFLFPKWNMEKQRFLTDVLHEVMLLDGLASSHPISQQVFEATDI 488
Query 56 DNFYTATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADA---- 111
D + Y KGA ++R+ ++G + F++ ++ Y H A DD +++A
Sbjct 489 DRVFDWIAYKKGAALIRMLANVMGQTLFQRALNDYLMTHMYGNAARDDLWNKLSEAMQRE 548
Query 112 -NGINLDQ-MDRWYSQAGTPRLEVLRSEYKEDEKAFEISFRQHTPPTRGQETKRPQL--- 166
IN+ Q MDRW Q G P + + +++ ++ + IS ++H + + P+L
Sbjct 549 GKDINITQVMDRWTLQMGYPVVTISKNDSLDN--SITIS-QEHFVYDTDAKIQNPELFNK 605
Query 167 -----IPIKIGLIGRASHQDLLQPAVVLEMTEEEQTFRV 200
IP+ + +G ASH + ++ +T + + RV
Sbjct 606 SFQWQIPLTLA-VGNASH---ISTETIIWVTNKSEAHRV 640
> sce:YHR047C AAP1, AAP1'; Aap1p (EC:3.4.11.-)
Length=856
Score = 47.8 bits (112), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 41/154 (26%), Positives = 70/154 (45%), Gaps = 14/154 (9%)
Query 55 MDNFYTATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADANGI 114
++ + A Y KG+ ++R+ LG F KG+ Y + A D A+ADA+G
Sbjct 377 INQIFDAISYSKGSSLLRMISKWLGEETFIKGVSQYLNKFKYGNAKTGDLWDALADASGK 436
Query 115 NL-DQMDRWYSQAGTPRLEVLRSEYKEDEKAFEISFRQHTPPTRG--QETKRPQLIPIKI 171
++ M+ W + G P L V E+K +I+ QH + G +E + + PI +
Sbjct 437 DVCSVMNIWTKRVGFPVLSV--KEHKN-----KITLTQHRYLSTGDVKEEEDTTIYPILL 489
Query 172 GL---IGRASHQDLLQPAVVLEMTEEEQTFRVRG 202
L G + L + + E+ EE F++ G
Sbjct 490 ALKDSTGIDNTLVLNEKSATFELKNEE-FFKING 522
> hsa:2028 ENPEP, APA, CD249, gp160; glutamyl aminopeptidase (aminopeptidase
A) (EC:3.4.11.7); K11141 glutamyl aminopeptidase
[EC:3.4.11.7]
Length=957
Score = 47.8 bits (112), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 17/143 (11%)
Query 1 LKEGLTVFREQLFMGTFMSAGVQRIKE---VADLISRQFPEDDGPMA-HAI-----RPES 51
L EG F E F+G + ++++ + D++ Q EDD M+ H I P+
Sbjct 414 LNEGFASFFE--FLGVNHAETDWQMRDQMLLEDVLPVQ--EDDSLMSSHPIIVTVTTPDE 469
Query 52 YLAMDNFYTATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADA 111
+ + + Y KG+ ++R+ + F+KG +Y +++ K A DF AA+ +A
Sbjct 470 ---ITSVFDGISYSKGSSILRMLEDWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEA 526
Query 112 NGINLDQ-MDRWYSQAGTPRLEV 133
+ + + + MD W Q G P L V
Sbjct 527 SRLPVKEVMDTWTRQMGYPVLNV 549
> mmu:13809 Enpep, 6030431M22Rik, APA, Bp-1/6C3, Ly-51, Ly51;
glutamyl aminopeptidase (EC:3.4.11.7); K11141 glutamyl aminopeptidase
[EC:3.4.11.7]
Length=945
Score = 47.0 bits (110), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 38/140 (27%), Positives = 63/140 (45%), Gaps = 11/140 (7%)
Query 1 LKEGLTVFREQLFMG-TFMSAGVQRIKEVADLISRQFP--EDDGPMAH---AIRPESYLA 54
L EG F E F+G Q + +V L+ FP EDD M+ + +
Sbjct 406 LNEGFASFFE--FLGVNHAEKDWQMLSQV--LLEDVFPVQEDDSLMSSHPVVVTVSTPAE 461
Query 55 MDNFYTATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADANGI 114
+ + + Y KGA ++R+ + F+KG +Y K+ A DF ++ +A+ +
Sbjct 462 ITSVFDGISYSKGASILRMLQDWITPEKFQKGCQIYLKKFQFANAKTSDFWDSLQEASNL 521
Query 115 NLDQ-MDRWYSQAGTPRLEV 133
+ + MD W SQ G P + V
Sbjct 522 PVKEVMDTWTSQMGYPVVTV 541
> sce:YKL157W APE2, LAP1, YKL158W; Aminopeptidase yscII; may have
a role in obtaining leucine from dipeptide substrates; sequence
coordinates have changed since RT-PCR analysis showed
that the adjacent ORF YKL158W comprises the 5' exon of APE2/YKL157W;
K13721 aminopeptidase 2 [EC:3.4.11.-]
Length=935
Score = 47.0 bits (110), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 7/99 (7%)
Query 55 MDNFYTATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADANGI 114
++ + A Y KGA ++R+ LG F KG+ Y + A +D A+ADA+G
Sbjct 473 INQIFDAISYSKGASLLRMISKWLGEETFIKGVSQYLNKFKYGNAKTEDLWDALADASGK 532
Query 115 NL-DQMDRWYSQAGTPRLEVLRSEYKEDEKAFEISFRQH 152
++ M+ W + G P + V ED +I+FRQ+
Sbjct 533 DVRSVMNIWTKKVGFPVISV-----SEDGNG-KITFRQN 565
> dre:555317 aminopeptidase N-like
Length=956
Score = 41.6 bits (96), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 9/88 (10%)
Query 55 MDNFYTATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAM---ADA 111
++ + A Y KGA V+R+ L S F KG+ Y + H D + AD+
Sbjct 464 IEELFDAVTYSKGAAVLRMLSEFLSESVFAKGLHNYLQEHAYSNTVYTDLWKKLQEVADS 523
Query 112 NG-INL-----DQMDRWYSQAGTPRLEV 133
+G ++L + M+RW QAG P + +
Sbjct 524 DGNVHLPASIEEIMNRWILQAGFPVVTI 551
> cel:T07F10.1 hypothetical protein
Length=988
Score = 40.4 bits (93), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 41/152 (26%), Positives = 61/152 (40%), Gaps = 20/152 (13%)
Query 1 LKEGLTVFREQLFMGT-FMSAGVQRIKE--VADLISRQFPEDDGPMAHAIRPESYLAM-- 55
L EG E ++GT +S G R++E D + D H + + AM
Sbjct 417 LNEGFATLVE--YLGTDEISDGNMRMREWFTMDALWSALAADSVASTHPLTFKIDKAMEV 474
Query 56 -DNFYTATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADA--- 111
D+F + T YDKG V+ + +G F G++ Y RH A + A+ +
Sbjct 475 LDSFDSVT-YDKGGAVLAMVRKTIGEENFNTGINHYLTRHQFDNADAGNLLTALGEKIPD 533
Query 112 -----NGINLDQ---MDRWYSQAGTPRLEVLR 135
G+ L+ MD W Q G P L R
Sbjct 534 SVMGPKGVKLNISEFMDPWTKQLGYPLLNASR 565
> dre:558452 fd60b03, wu:fd60b03; si:ch211-200o3.4 (EC:3.4.11.2)
Length=946
Score = 38.9 bits (89), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 36/147 (24%), Positives = 60/147 (40%), Gaps = 22/147 (14%)
Query 1 LKEGLTVFREQLFMGTFMS-AGVQRIK-EVADLI-----SRQFPEDDGPMAHAIRPESY- 52
LKEG T+MS GV+ + ++ DLI F D +H + +Y
Sbjct 403 LKEGF---------ATYMSYKGVEAVGWDLKDLIVLREIQTAFQMDSLNTSHPLSMNAYD 453
Query 53 ----LAMDNFYTATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAM 108
+ + Y KGA V+R+ T +G + F KG+ +Y + + D +
Sbjct 454 VQTSSQISELFDDITYSKGAAVLRMLATRMGENEFMKGVKMYLSKFQFENTVPKDLWECL 513
Query 109 ADANGINLDQ-MDRWYSQAGTPRLEVL 134
I +D+ M W + G P L ++
Sbjct 514 NMDTHIKVDEFMKTWTEEVGYPVLTII 540
> dre:322533 anpep, fb64c05, wu:fb64c05, zgc:136771; alanyl (membrane)
aminopeptidase (EC:3.4.11.2); K11140 aminopeptidase
N [EC:3.4.11.2]
Length=965
Score = 37.7 bits (86), Expect = 0.048, Method: Compositional matrix adjust.
Identities = 39/151 (25%), Positives = 59/151 (39%), Gaps = 23/151 (15%)
Query 1 LKEGLTVFREQLFMGTFMSAGVQRIKEVADL--ISRQFPEDDGPMAHAI--------RPE 50
L EG + E ++G + + IK++ L + R F D +H + RPE
Sbjct 408 LNEGFASYVE--YLGADEAEPLWNIKDLIVLNDVHRVFAIDALASSHPLSSKEEDVQRPE 465
Query 51 SYLAMDNFYTATVYDKGAEVVRIYYTLLGASGFRKGMDLY---FKRHDNKPATCDDFRAA 107
+ + Y KGA V+R+ L F +G+ Y FK ++ D
Sbjct 466 Q---ISEVFDTISYSKGASVLRMLSNFLSEDVFTQGLRTYLEHFKFNNTVYTDLWDHLQM 522
Query 108 MADANGINL-----DQMDRWYSQAGTPRLEV 133
D G L D MDRW Q G P + +
Sbjct 523 AVDETGTELPRSVKDIMDRWVLQMGFPVVTI 553
> mmu:240028 Lnpep, 2010309L07Rik, 4732490P18Rik, CAP, IRAP, PLAP,
gp160, vp165; leucyl/cystinyl aminopeptidase (EC:3.4.11.3);
K01257 cystinyl aminopeptidase [EC:3.4.11.3]
Length=1025
Score = 37.7 bits (86), Expect = 0.051, Method: Compositional matrix adjust.
Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 13/158 (8%)
Query 55 MDNFYTATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADANGI 114
++ + + Y KGA ++ + + L FR + LY H DD + +
Sbjct 540 IEEMFDSLSYFKGASLLLMLKSYLSEDVFRHAVILYLHNHSYAAIQSDDLWDSFNEVTDK 599
Query 115 NLD---QMDRWYSQAGTPRLEVLR--SEYKEDEKAFEISFRQHTPPTRGQETKRPQLIPI 169
LD M W Q G P + V R +E ++ F F + P ++ +T IPI
Sbjct 600 TLDVKKMMKTWTLQKGFPLVTVQRKGTELLLQQERF---FLRMQPESQPSDTSHLWHIPI 656
Query 170 KIGLIGRA-----SHQDLLQPAVVLEMTEEEQTFRVRG 202
GR S L + + V+ +TE+ Q +V
Sbjct 657 SYVTDGRNYSEYRSVSLLDKKSDVINLTEQVQWVKVNS 694
> mmu:16790 Anpep, Apn, Cd13, Lap-1, Lap1, P150; alanyl (membrane)
aminopeptidase (EC:3.4.11.2); K11140 aminopeptidase N [EC:3.4.11.2]
Length=966
Score = 36.2 bits (82), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 31/133 (23%), Positives = 50/133 (37%), Gaps = 15/133 (11%)
Query 58 FYTATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADANGINLD 117
+ + Y KGA V+R+ + L F+KG+ Y + D + A +N
Sbjct 470 LFDSITYSKGASVIRMLSSFLTEDLFKKGLSSYLHTYQYSNTVYLDLWEHLQKA--VNQQ 527
Query 118 Q-----------MDRWYSQAGTPRLEVLRSEYKEDEKAFEISFRQHTPPTRGQETKRPQL 166
MDRW Q G P + V + + +K F + + + TR E +
Sbjct 528 TAVQPPATVRTIMDRWILQMGFPVITVNTNTGEISQKHFLLDSKSNV--TRPSEFNYIWI 585
Query 167 IPIKIGLIGRASH 179
PI G+ H
Sbjct 586 APIPFLKSGQEDH 598
> cel:Y67D8C.9 hypothetical protein
Length=1087
Score = 34.7 bits (78), Expect = 0.41, Method: Compositional matrix adjust.
Identities = 31/145 (21%), Positives = 62/145 (42%), Gaps = 10/145 (6%)
Query 1 LKEGLTVFREQLFMGTF--MSAGVQRIKEVADLISRQFPEDDG-PMAHAIRPESYLAMDN 57
L EG F M T ++A + +A LI Q ED + + ES + +
Sbjct 459 LNEGFATFYVYEMMSTERPVTAQFEYYDSLASLILAQSEEDHRLSLVRELATESQVE-SS 517
Query 58 FYTATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADANGINLD 117
F+ +Y KG ++R+ L+ F+ + Y +++ + + DD A++ +
Sbjct 518 FHPTNLYTKGCVLIRMLRDLVSDFDFKAAVRRYLRKNAYRSVSRDDLFASLPAYADHGAE 577
Query 118 Q------MDRWYSQAGTPRLEVLRS 136
Q ++ W+ G P + ++R+
Sbjct 578 QEKLSHVLEGWFVNEGIPEITLIRN 602
> cel:R03G8.6 hypothetical protein
Length=747
Score = 34.3 bits (77), Expect = 0.51, Method: Compositional matrix adjust.
Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 15/106 (14%)
Query 39 DDGPMAHAIRPESYLAMDNFYTATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKP 98
+DG ++ M+N ATVY KG VR+ + G F + + Y ++ N+
Sbjct 385 NDGGVSLNFGKNLSSVMNN--AATVYMKGCSFVRMLENIFGTEYFNEAIKFYLEK--NQY 440
Query 99 ATCDD------FRAA--MADANG--INLDQMDR-WYSQAGTPRLEV 133
DD FR + D NG ++++ R W Q G P ++V
Sbjct 441 DNVDDNDLYEAFRTSSETLDTNGKPFDIEKFARCWTHQNGFPTIQV 486
> hsa:64167 ERAP2, FLJ23633, FLJ23701, FLJ23807, L-RAP, LRAP;
endoplasmic reticulum aminopeptidase 2 (EC:3.4.11.-); K13723
endoplasmic reticulum aminopeptidase 2 [EC:3.4.11.-]
Length=960
Score = 33.9 bits (76), Expect = 0.69, Method: Compositional matrix adjust.
Identities = 14/48 (29%), Positives = 28/48 (58%), Gaps = 0/48 (0%)
Query 64 YDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADA 111
Y+KGA ++ + LG F+KG+ Y K+ + A DD ++++++
Sbjct 455 YNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNS 502
> hsa:51752 ERAP1, A-LAP, ALAP, APPILS, ARTS-1, ARTS1, ERAAP,
ERAAP1, KIAA0525, PILS-AP, PILSAP; endoplasmic reticulum aminopeptidase
1; K09604 adipocyte-derived leucine aminopeptidase
[EC:3.4.11.-]
Length=941
Score = 33.9 bits (76), Expect = 0.69, Method: Compositional matrix adjust.
Identities = 15/46 (32%), Positives = 24/46 (52%), Gaps = 0/46 (0%)
Query 64 YDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMA 109
YDKGA ++ + L A F+ G+ Y ++H K +D +MA
Sbjct 438 YDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMA 483
> dre:555478 aminopeptidase N-like; K11140 aminopeptidase N [EC:3.4.11.2]
Length=960
Score = 33.1 bits (74), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 47/205 (22%), Positives = 79/205 (38%), Gaps = 21/205 (10%)
Query 1 LKEGLTVFREQLFMGTFMSAGVQRIKEVADL--ISRQFPEDDGPMAHAI-RPESYL---- 53
L EG + E ++G + IK+ L + R F D +H + R E +
Sbjct 401 LNEGFASYVE--YLGADHAEPTWNIKDQIILYDMQRAFAVDSLTSSHPLSRKEEEVNTPA 458
Query 54 AMDNFYTATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPAT----CDDFRAAMA 109
+ ++ Y KGA V+++ L F KG+ Y K+ + D + ++
Sbjct 459 EISEMFSTISYSKGAAVLKMLSEFLTEPVFAKGLSNYLKQFAFGSSVHSDLWDHLQKSLD 518
Query 110 DANGINL-----DQMDRWYSQAGTPRLEVLRSEYKEDEKAFEISFRQHTPPTRGQETKRP 164
A G+ L + M RW Q G P + + +K F + + R E
Sbjct 519 QAPGMKLPRSIHEIMSRWILQMGFPVITIDTRTGNVSQKHFLV--EKDAVVERKSEFNYE 576
Query 165 QLIPIKIGLIGRASHQ-DLLQPAVV 188
+PIK G+ Q LLQ + +
Sbjct 577 WFVPIKWMKKGQVQDQMWLLQKSAI 601
> xla:495476 anpep; alanyl (membrane) aminopeptidase; K11140 aminopeptidase
N [EC:3.4.11.2]
Length=963
Score = 32.7 bits (73), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 30/131 (22%), Positives = 52/131 (39%), Gaps = 11/131 (8%)
Query 58 FYTATVYDKGAEVVRIYYTLLGASGFRKGMDLYFK--RHDNKPAT--CDDFRAAMADANG 113
+ + Y KGA V+R+ L F G+ Y K +DN + + A+ +
Sbjct 466 LFDSIAYSKGASVIRMLSEFLTEPLFVNGLASYLKGFEYDNTVYSDLWTHLQMAVDNQTA 525
Query 114 INL-----DQMDRWYSQAGTPRLEVLRSEYKEDEKAFEISFRQHTPPTRGQETKRPQLIP 168
+ L D MD W Q G P +++ + +K F + + TR ++P
Sbjct 526 VQLPLPIKDIMDTWVLQMGFPVVKIDTATGIVTQKHFLLD--PDSVVTRPSPFDYKWIVP 583
Query 169 IKIGLIGRASH 179
I + G+ H
Sbjct 584 ISFQISGKNDH 594
> hsa:4012 LNPEP, CAP, IRAP, P-LAP, PLAP; leucyl/cystinyl aminopeptidase
(EC:3.4.11.3); K01257 cystinyl aminopeptidase [EC:3.4.11.3]
Length=1025
Score = 32.7 bits (73), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 46/207 (22%), Positives = 78/207 (37%), Gaps = 18/207 (8%)
Query 1 LKEGLTVFREQLFMGTFMSAGVQRIKEVADLISRQFP---EDDGPMAHAIRP--ESYLAM 55
L EG F E + + + D + +F +D +H I +S +
Sbjct 485 LNEGFATFMEYFSLEKIF----KELSSYEDFLDARFKTMKKDSLNSSHPISSSVQSSEQI 540
Query 56 DNFYTATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDFRAAMADANGIN 115
+ + + Y KG+ ++ + T L F+ + LY H DD + +
Sbjct 541 EEMFDSLSYFKGSSLLLMLKTYLSEDVFQHAVVLYLHNHSYASIQSDDLWDSFNEVTNQT 600
Query 116 LD---QMDRWYSQAGTPRLEVLRSEYKEDEKAFEISFRQHTPPTRGQETKRPQLIPIKIG 172
LD M W Q G P + V + + KE E F P + +T IP+
Sbjct 601 LDVKRMMKTWTLQKGFPLVTV-QKKGKELFIQQERFFLNMKPEIQPSDTSYLWHIPLSYV 659
Query 173 LIGR--ASHQD---LLQPAVVLEMTEE 194
GR + +Q L + + V+ +TEE
Sbjct 660 TEGRNYSKYQSVSLLDKKSGVINLTEE 686
> cel:Y42A5A.1 hypothetical protein
Length=1045
Score = 31.6 bits (70), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 12/89 (13%)
Query 61 ATVYDKGAEVVRIYYTLLGASGFRKGMDLYFKRHDNKPATCDDF---------RAAMADA 111
A +Y K A ++R+ L+ FR+G+ + K A +D +A
Sbjct 543 AIIYKKSAIIIRMIERLVEEDIFRQGLKRFLNTFLYKNADHEDLFNVLVYVHDSSAGGHL 602
Query 112 NGINL---DQMDRWYSQAGTPRLEVLRSE 137
G N D MD W QA P + V R E
Sbjct 603 RGQNFSLSDVMDTWIRQAHFPVIHVNRKE 631
> mmu:26885 Casp8ap2, AA387232, D4Ertd659e, FLASH, mKIAA1315;
caspase 8 associated protein 2
Length=1962
Score = 30.0 bits (66), Expect = 9.8, Method: Composition-based stats.
Identities = 29/112 (25%), Positives = 47/112 (41%), Gaps = 11/112 (9%)
Query 175 GRASHQDLLQPAVVLEMTEEEQTFRVRGVREDCVPSILRGFSAPVRLINRPQTAKESAFL 234
G H +L AV++E + + ++R P + G A L + P+T KE+
Sbjct 1499 GFQYHPNLPMHAVIMEKSNDHFIVKIRRATPSTSPGLKHGVVAEESLTSLPRTGKEAG-- 1556
Query 235 LAYDTDPVTKWFASRALA-------TPIVISRSKRISAKGNAQKLEQLPDDY 279
+A + +P F S L T I +SK + N+ Q+PD Y
Sbjct 1557 VATEKEP--NLFQSTVLKPVKDLENTDKNIDKSKLTHEEQNSIVQTQVPDIY 1606
Lambda K H
0.320 0.135 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 11647553988
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
Posted date: Sep 17, 2011 11:19 AM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40