bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
164,496 sequences; 82,071,388 total letters
Query= Eace_0621_orf3
Length=360
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_024350 aminopeptidase N, putative (EC:3.4.11.2); K0... 525 1e-148
bbo:BBOV_IV005930 23.m06519; aminopeptidase (EC:3.4.11.2); K01... 484 2e-136
tpv:TP01_0397 alpha-aminoacylpeptide hydrolase (EC:3.4.11.2); ... 470 4e-132
cpv:cgd8_3430 zincin/aminopeptidase N like metalloprotease ; K... 455 1e-127
eco:b0932 pepN, ECK0923, JW0915; aminopeptidase N (EC:3.4.11.2... 439 7e-123
ath:AT1G63770 peptidase M1 family protein; K01256 aminopeptida... 436 7e-122
tgo:TGME49_021310 aminopeptidase N, putative (EC:3.4.11.2) 429 8e-120
tgo:TGME49_024460 aminopeptidase N, putative (EC:3.4.11.2) 422 8e-118
pfa:MAL13P1.56 M1-family aminopeptidase (EC:3.4.11.-); K13725 ... 388 1e-107
hsa:2028 ENPEP, APA, CD249, gp160; glutamyl aminopeptidase (am... 130 6e-30
hsa:9520 NPEPPS, AAP-S, MP100, PSA; aminopeptidase puromycin s... 129 2e-29
mmu:19155 Npepps, AAP-S, MGC102199, MP100, Psa, R74825, goku; ... 128 3e-29
cel:T07F10.1 hypothetical protein 127 8e-29
dre:407726 npepps, Psa, fb68d07, sb:cb848, wu:fb68d07; aminope... 126 1e-28
ath:AT4G33090 APM1; APM1 (AMINOPEPTIDASE M1); aminopeptidase; ... 124 5e-28
cel:F49E8.3 pam-1; Puromycin-sensitive AMinopeptidase family m... 122 1e-27
dre:322533 anpep, fb64c05, wu:fb64c05, zgc:136771; alanyl (mem... 121 4e-27
mmu:13809 Enpep, 6030431M22Rik, APA, Bp-1/6C3, Ly-51, Ly51; gl... 119 2e-26
dre:504088 enpep, im:7152184, si:ch211-146m5.2; glutamyl amino... 117 9e-26
sce:YHR047C AAP1, AAP1'; Aap1p (EC:3.4.11.-) 115 2e-25
mmu:16790 Anpep, Apn, Cd13, Lap-1, Lap1, P150; alanyl (membran... 114 5e-25
sce:YKL157W APE2, LAP1, YKL158W; Aminopeptidase yscII; may hav... 114 8e-25
mmu:240028 Lnpep, 2010309L07Rik, 4732490P18Rik, CAP, IRAP, PLA... 110 1e-23
dre:555317 aminopeptidase N-like 107 1e-22
hsa:4012 LNPEP, CAP, IRAP, P-LAP, PLAP; leucyl/cystinyl aminop... 106 1e-22
xla:379719 hypothetical protein MGC69084 105 3e-22
dre:555478 aminopeptidase N-like; K11140 aminopeptidase N [EC:... 104 4e-22
hsa:290 ANPEP, APN, CD13, GP150, LAP1, P150, PEPN; alanyl (mem... 104 5e-22
dre:322814 fb73h12, wu:fb73h12; zgc:66103 (EC:3.4.11.3); K0125... 103 7e-22
xla:495293 lnpep; leucyl/cystinyl aminopeptidase (EC:3.4.11.3)... 103 1e-21
xla:495476 anpep; alanyl (membrane) aminopeptidase; K11140 ami... 102 2e-21
hsa:51752 ERAP1, A-LAP, ALAP, APPILS, ARTS-1, ARTS1, ERAAP, ER... 101 5e-21
mmu:237553 Trhde, 9330155P21Rik, MGC40831; TRH-degrading enzym... 98.6 4e-20
hsa:29953 TRHDE, FLJ22381, PAP-II, PGPEP2, TRH-DE; thyrotropin... 97.1 9e-20
cel:Y67D8C.9 hypothetical protein 96.7 1e-19
mmu:80898 Erap1, Arts1, ERAAP, PILSA, PILSAP; endoplasmic reti... 96.3 2e-19
dre:100144556 zgc:172163; K13723 endoplasmic reticulum aminope... 95.5 3e-19
hsa:64167 ERAP2, FLJ23633, FLJ23701, FLJ23807, L-RAP, LRAP; en... 95.1 4e-19
dre:564068 endoplasmic reticulum aminopeptidase 1-like; K09604... 94.7 5e-19
cel:R03G8.4 hypothetical protein 91.3 5e-18
dre:100004744 aminopeptidase N-like 91.3 5e-18
cel:R03G8.6 hypothetical protein 90.1 1e-17
dre:558452 fd60b03, wu:fd60b03; si:ch211-200o3.4 (EC:3.4.11.2) 89.7 2e-17
dre:100006808 trh-de, PAP-II; thyrotropin-releasing hormone-de... 87.4 9e-17
dre:562409 thyrotropin-releasing hormone-degrading ectoenzyme-... 86.7 1e-16
cel:T16G12.1 hypothetical protein 84.3 7e-16
cel:F49B2.6 hypothetical protein 80.5 1e-14
hsa:4048 LTA4H; leukotriene A4 hydrolase (EC:3.3.2.6); K01254 ... 80.5 1e-14
cel:C42C1.11 hypothetical protein 80.1 1e-14
cel:ZC416.6 hypothetical protein; K01254 leukotriene-A4 hydrol... 79.3 2e-14
> tgo:TGME49_024350 aminopeptidase N, putative (EC:3.4.11.2);
K01256 aminopeptidase N [EC:3.4.11.2]
Length=1419
Score = 525 bits (1351), Expect = 1e-148, Method: Compositional matrix adjust.
Identities = 242/356 (67%), Positives = 283/356 (79%), Gaps = 0/356 (0%)
Query 1 KLKGLYVSGSALVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEE 60
+L GLY SG+ LVTQCEAEGFRRITYFLDRPDV++ +KVRL A++ PVLLSNGN E
Sbjct 641 QLMGLYKSGALLVTQCEAEGFRRITYFLDRPDVMSLFKVRLAADEKACPVLLSNGNMVES 700
Query 61 GLVHGSPDRHFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHK 120
G V G RHFAVF DP KP YLFA++AG+ +I FTT SG V ++++SEP K
Sbjct 701 GKVEGEKGRHFAVFEDPFQKPCYLFALVAGDLKSISQSFTTMSGRNVKVSIFSEPEDSSK 760
Query 121 LEWAMHSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQT 180
L WA+ SV SMKW+EE FGREYDLD+FNV C DFN GAMENKGLNIFN LLLAD T
Sbjct 761 LTWALESVLKSMKWDEERFGREYDLDVFNVVCAKDFNMGAMENKGLNIFNAALLLADPST 820
Query 181 STDDDFERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRI 240
+TD +++R+L VVGHEYFHNWTGNRVT RDWFQLTLKEGLTVFR+QLF + SA V+RI
Sbjct 821 TTDAEYQRILNVVGHEYFHNWTGNRVTCRDWFQLTLKEGLTVFRDQLFTADMCSAAVKRI 880
Query 241 KEVADLISRQFAEDDGPMAHPIRPESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRK 300
++V L SRQFAED GPMAHPIRPE+Y+AMDNFYTATVYDKGAEV+R+YHTLLG +GFRK
Sbjct 881 EDVVFLRSRQFAEDSGPMAHPIRPETYIAMDNFYTATVYDKGAEVIRMYHTLLGEAGFRK 940
Query 301 GMDMYFERHDNTAATCDDFRAAMADANRINLDQMDRWYSQAGTPRLEVLRSEYKED 356
GMD+YF+RHD A TCDDFRAAMADAN +L Q +RWY QAGTP + V + ++ D
Sbjct 941 GMDLYFKRHDGKAVTCDDFRAAMADANGRDLGQFERWYLQAGTPEVTVSEAVFQPD 996
> bbo:BBOV_IV005930 23.m06519; aminopeptidase (EC:3.4.11.2); K01256
aminopeptidase N [EC:3.4.11.2]
Length=846
Score = 484 bits (1246), Expect = 2e-136, Method: Compositional matrix adjust.
Identities = 227/351 (64%), Positives = 274/351 (78%), Gaps = 3/351 (0%)
Query 1 KLKGLYVSGSALVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEE 60
+L GLY + TQCE+ GFRRITYFLDRPDVL++Y+VRL A+K +YPVLLSNGNK +
Sbjct 143 QLSGLYKNSQLFTTQCESHGFRRITYFLDRPDVLSRYRVRLRADKDQYPVLLSNGNKVDS 202
Query 61 GLVHGSPDRHFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHK 120
G + GS + FA F DP PKPSYLFA++AG +I+ F T SG +V + V SEP K
Sbjct 203 G-IDGS--KIFAEFVDPFPKPSYLFALVAGNLKSIKKTFRTMSGRDVLVEVSSEPEDATK 259
Query 121 LEWAMHSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQT 180
LEWA+ SV +MKW+EE +GREYDLD F+V C FN GAMENKGLNIFN +LLLAD+ T
Sbjct 260 LEWALESVLKAMKWDEESYGREYDLDEFHVVCTRAFNFGAMENKGLNIFNSSLLLADVNT 319
Query 181 STDDDFERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRI 240
+TD +F +++VVGHEYFHNWTGNRVT RDWFQLTLKEGLTVFRE F G + S + RI
Sbjct 320 TTDSEFNTIMSVVGHEYFHNWTGNRVTCRDWFQLTLKEGLTVFRESEFAGDMSSPLITRI 379
Query 241 KEVADLISRQFAEDDGPMAHPIRPESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRK 300
+V +L + QFAED GP+AHPIRPESY++MDNFYT TVYDKG+EV+ +Y TLLG GFRK
Sbjct 380 TDVRNLRTYQFAEDAGPLAHPIRPESYISMDNFYTTTVYDKGSEVIGMYKTLLGKDGFRK 439
Query 301 GMDMYFERHDNTAATCDDFRAAMADANRINLDQMDRWYSQAGTPRLEVLRS 351
GMD+YFERHD+ A TCDDFRAAMADAN ++L Q +RWY QAGTP +EVL +
Sbjct 440 GMDLYFERHDSHAVTCDDFRAAMADANGVDLTQFERWYFQAGTPEVEVLEA 490
> tpv:TP01_0397 alpha-aminoacylpeptide hydrolase (EC:3.4.11.2);
K01256 aminopeptidase N [EC:3.4.11.2]
Length=1020
Score = 470 bits (1209), Expect = 4e-132, Method: Compositional matrix adjust.
Identities = 220/344 (63%), Positives = 264/344 (76%), Gaps = 3/344 (0%)
Query 1 KLKGLYVSGSALVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEE 60
KL GLY S +A TQCE GFRRITY+LDRPDVL+ ++VR++A+K YPVLLSNGN+ +
Sbjct 265 KLVGLYKSSAAFCTQCEPHGFRRITYYLDRPDVLSSFRVRVQADKKLYPVLLSNGNRVDS 324
Query 61 GLVHGSPDRHFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHK 120
G + RHFA F DP PKP YLFA++AG A+I F T SG V + + SEP + K
Sbjct 325 GDLGT---RHFAEFVDPFPKPCYLFALVAGNLASISTTFKTMSGRNVLVQLSSEPEDVGK 381
Query 121 LEWAMHSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQT 180
L+WA+ SV +MKW+EE +GREYDLD F+V V DFN GAMENKGLNIFN LLLAD+ T
Sbjct 382 LQWALESVVKAMKWDEEKYGREYDLDEFHVFAVRDFNFGAMENKGLNIFNTALLLADVNT 441
Query 181 STDDDFERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRI 240
+TD +F R+L+VVGHEYFHNWTGNRVT RDWFQLTLKEGLTVFRE F G + S RI
Sbjct 442 TTDAEFVRILSVVGHEYFHNWTGNRVTCRDWFQLTLKEGLTVFREHQFCGDMSSTLSNRI 501
Query 241 KEVADLISRQFAEDDGPMAHPIRPESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRK 300
+EV L+S QF ED GPM+HPIRPESY++MDNFYT TVYDKGA V+ +Y +LLG GFR+
Sbjct 502 REVQYLMSVQFPEDSGPMSHPIRPESYISMDNFYTPTVYDKGAFVIGMYESLLGVDGFRR 561
Query 301 GMDMYFERHDNTAATCDDFRAAMADANRINLDQMDRWYSQAGTP 344
GMD+YF+RHD +A TCDDFR AMADAN +L Q +RWY Q+GTP
Sbjct 562 GMDLYFKRHDLSAVTCDDFRLAMADANNKDLTQFERWYYQSGTP 605
> cpv:cgd8_3430 zincin/aminopeptidase N like metalloprotease ;
K01256 aminopeptidase N [EC:3.4.11.2]
Length=936
Score = 455 bits (1171), Expect = 1e-127, Method: Compositional matrix adjust.
Identities = 207/352 (58%), Positives = 260/352 (73%), Gaps = 0/352 (0%)
Query 4 GLYVSGSALVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEGLV 63
GLY S TQCE++GFRRIT+FLDRPDV+ K++VR+E +K K PVLLSNGN E+G V
Sbjct 145 GLYYSAGVYSTQCESDGFRRITFFLDRPDVMCKFRVRIEGDKTKSPVLLSNGNLLEKGDV 204
Query 64 HGSPDRHFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEW 123
GS +RHFA+F DP PKP YLFA++AG + DKF TKSG V L VYSEP + +L
Sbjct 205 QGSENRHFAIFVDPFPKPCYLFAVVAGVLGRLEDKFITKSGKTVRLFVYSEPKYVDRLRL 264
Query 124 AMHSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTD 183
AM S+K++MKW+E+ FG EYDL+IFN+ V FN GAMENK LNIFNC+ LLA + D
Sbjct 265 AMESLKLAMKWDEDRFGLEYDLEIFNIVAVESFNFGAMENKSLNIFNCSCLLASENITPD 324
Query 184 DDFERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEV 243
F +L++VGHEYFHN+TGNRVT RDWFQLTLKEGLTV+R+Q F + +++ ++
Sbjct 325 YFFTNILSIVGHEYFHNYTGNRVTCRDWFQLTLKEGLTVYRDQEFSRDCIDRLSEQLGDI 384
Query 244 ADLISRQFAEDDGPMAHPIRPESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKGMD 303
L + QF ED GP+AHPIRP+S ++ +N YT+TVY KGAEVVR+Y T+LG GFRKGMD
Sbjct 385 EVLRNYQFQEDSGPLAHPIRPDSIVSTNNLYTSTVYRKGAEVVRMYETILGREGFRKGMD 444
Query 304 MYFERHDNTAATCDDFRAAMADANRINLDQMDRWYSQAGTPRLEVLRSEYKE 355
+YF RHD A TCDDFR AM DAN N Q +RWY QAGTP +EV+ ++ +
Sbjct 445 LYFARHDGQAVTCDDFRKAMEDANNYNFTQFERWYDQAGTPEVEVVSIDHNK 496
> eco:b0932 pepN, ECK0923, JW0915; aminopeptidase N (EC:3.4.11.2);
K01256 aminopeptidase N [EC:3.4.11.2]
Length=870
Score = 439 bits (1130), Expect = 7e-123, Method: Compositional matrix adjust.
Identities = 207/347 (59%), Positives = 254/347 (73%), Gaps = 2/347 (0%)
Query 2 LKGLYVSGSALVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEG 61
L+GLY SG AL TQCEAEGFR ITY+LDRPDVLA++ ++ A+K KYP LLSNGN+ +G
Sbjct 106 LEGLYQSGDALCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKIKYPFLLSNGNRVAQG 165
Query 62 LVHGSPDRHFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKL 121
+ RH+ + DP PKP YLFA++AG+F +RD FTT+SG EVAL +Y + L +
Sbjct 166 ELENG--RHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRA 223
Query 122 EWAMHSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTS 181
WAM S+K SMKW+EE FG EYDLDI+ + V FN GAMENKGLNIFN +LA T+
Sbjct 224 PWAMTSLKNSMKWDEERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTA 283
Query 182 TDDDFERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIK 241
TD D+ + V+GHEYFHNWTGNRVT RDWFQL+LKEGLTVFR+Q F + S V RI
Sbjct 284 TDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDLGSRAVNRIN 343
Query 242 EVADLISRQFAEDDGPMAHPIRPESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKG 301
V + QFAED PMAHPIRP+ + M+NFYT TVY+KGAEV+R+ HTLLG F+KG
Sbjct 344 NVRTMRGLQFAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIHTLLGEENFQKG 403
Query 302 MDMYFERHDNTAATCDDFRAAMADANRINLDQMDRWYSQAGTPRLEV 348
M +YFERHD +AATCDDF AM DA+ ++L RWYSQ+GTP + V
Sbjct 404 MQLYFERHDGSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPIVTV 450
> ath:AT1G63770 peptidase M1 family protein; K01256 aminopeptidase
N [EC:3.4.11.2]
Length=987
Score = 436 bits (1121), Expect = 7e-122, Method: Compositional matrix adjust.
Identities = 208/369 (56%), Positives = 264/369 (71%), Gaps = 15/369 (4%)
Query 2 LKGLYVSGSALVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEG 61
L+GLY S TQCEAEGFR+IT++ DRPD++AKY R+E +K YPVLLSNGN +G
Sbjct 202 LEGLYKSSGNFCTQCEAEGFRKITFYQDRPDIMAKYTCRVEGDKTLYPVLLSNGNLISQG 261
Query 62 LVHGSPDRHFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKL 121
+ G RH+A++ DP KP YLFA++AG+ + D FTT+SG +V+L +++ L K
Sbjct 262 DIEGG--RHYALWEDPFKKPCYLFALVAGQLVSRDDTFTTRSGRQVSLKIWTPAEDLPKT 319
Query 122 EWAMHSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTS 181
AM+S+K +MKW+E+ FG EYDLD+FN+ V DFN GAMENK LNIFN L+LA +T+
Sbjct 320 AHAMYSLKAAMKWDEDVFGLEYDLDLFNIVAVPDFNMGAMENKSLNIFNSKLVLASPETA 379
Query 182 TDDDFERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIK 241
TD D+ +L V+GHEYFHNWTGNRVT RDWFQL+LKEGLTVFR+Q F + S V+RI
Sbjct 380 TDADYAAILGVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDMGSRTVKRIA 439
Query 242 EVADLISRQFAEDDGPMAHPIRPESYMAMDNFYTATVYDK------------GAEVVRIY 289
+V+ L QF +D GPMAHP+RP SY+ MDNFYT TVY+K GAEVVR+Y
Sbjct 440 DVSKLRIYQFPQDAGPMAHPVRPHSYIKMDNFYTVTVYEKVWLFTNSVLLYAGAEVVRMY 499
Query 290 HTLLGASGFRKGMDMYFERHDNTAATCDDFRAAMADANRINLDQMDRWYSQAGTPRLEVL 349
TLLG GFRKG+D+YFERHD A TC+DF AAM DAN + +WYSQAGTP ++V+
Sbjct 500 KTLLGTQGFRKGIDLYFERHDEQAVTCEDFFAAMRDANNADFANFLQWYSQAGTPVVKVV 559
Query 350 RSEYKEDAQ 358
S Y DA+
Sbjct 560 -SSYNADAR 567
> tgo:TGME49_021310 aminopeptidase N, putative (EC:3.4.11.2)
Length=966
Score = 429 bits (1103), Expect = 8e-120, Method: Compositional matrix adjust.
Identities = 192/348 (55%), Positives = 263/348 (75%), Gaps = 0/348 (0%)
Query 1 KLKGLYVSGSALVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEE 60
+L GLYVS LVT EA+GFRRIT+FLDRPDV+ +++VRL A K YPVLLSNG E
Sbjct 152 RLSGLYVSDGVLVTHNEAQGFRRITFFLDRPDVMTQWRVRLTARKQDYPVLLSNGELVES 211
Query 61 GLVHGSPDRHFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHK 120
G P++HF+VF+DPH KPSYLFA++AG+ ++ + + + V ++V+S P + K
Sbjct 212 GDDPTDPEKHFSVFSDPHKKPSYLFALVAGKLHSVGHDYEKRDKSLVKVSVWSTPENVAK 271
Query 121 LEWAMHSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQT 180
L WA+ S+ +MK +E FGR+YD ++F++ CV+ FNAGAMENKGLNIFNC LLAD T
Sbjct 272 LSWALQSIIRAMKGDEILFGRDYDSNVFHIVCVNGFNAGAMENKGLNIFNCDSLLADPTT 331
Query 181 STDDDFERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRI 240
+TD+++ +L VV HEYFHNW+GNRVT+RDW +LTLKEGLTV+REQ FMG+ S+GV R+
Sbjct 332 TTDEEYRGILRVVAHEYFHNWSGNRVTLRDWTELTLKEGLTVYREQEFMGSQYSSGVARV 391
Query 241 KEVADLISRQFAEDDGPMAHPIRPESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRK 300
++ ++S+QF ED GP+AHP+RP+ Y ++DN Y+ TVY KGAE+ R+Y TLLG S FRK
Sbjct 392 EDARLVLSQQFREDSGPLAHPVRPDHYASVDNLYSVTVYKKGAEIFRMYATLLGPSAFRK 451
Query 301 GMDMYFERHDNTAATCDDFRAAMADANRINLDQMDRWYSQAGTPRLEV 348
G+++YF R+D AATC++FR+AM +A+ NL Q WY++ GTP +E+
Sbjct 452 GLNLYFSRYDGQAATCENFRSAMEEASGRNLSQFFLWYTREGTPEVEI 499
> tgo:TGME49_024460 aminopeptidase N, putative (EC:3.4.11.2)
Length=970
Score = 422 bits (1086), Expect = 8e-118, Method: Compositional matrix adjust.
Identities = 200/347 (57%), Positives = 250/347 (72%), Gaps = 3/347 (0%)
Query 2 LKGLYVSGSALVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEG 61
L GLY +G VT E GFRRITY +DRPDVLA Y V + A + P+LLSNG+K G
Sbjct 186 LFGLYKAGDIFVTLNEPSGFRRITYGVDRPDVLATYTVTVTAPR-HLPILLSNGDKVLSG 244
Query 62 LVHGSPDRHFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKL 121
+ +RHFA F DP PKPSYLFA++AG+FA++ +F T SG V + +Y++ Q ++L
Sbjct 245 --YAGENRHFAKFVDPFPKPSYLFALVAGDFASVSGEFVTMSGRSVTVTIYAQHHQRNQL 302
Query 122 EWAMHSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTS 181
+WA+ S+ +M+W+EE FGREY F V CV FN GAMEN LNIF C+LLLAD + +
Sbjct 303 QWALRSLLRAMRWDEETFGREYQYSEFRVLCVEVFNPGAMENTSLNIFTCSLLLADPKLT 362
Query 182 TDDDFERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIK 241
TD D ++ VV HEYFHNWTGNRVTV+DWFQLTLKEGLT+FR F S ++RI
Sbjct 363 TDADHRLIVDVVSHEYFHNWTGNRVTVQDWFQLTLKEGLTMFRNNSFTEETTSRAMKRIG 422
Query 242 EVADLISRQFAEDDGPMAHPIRPESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKG 301
+VAD++S QF ED GP AHPIRPE+Y +++N YT TVY KGAEV R+Y T+LG GFR+G
Sbjct 423 DVADILSIQFREDSGPFAHPIRPETYKSIENLYTRTVYLKGAEVNRMYRTMLGPKGFRRG 482
Query 302 MDMYFERHDNTAATCDDFRAAMADANRINLDQMDRWYSQAGTPRLEV 348
MD+YF+RHD A TCDD RAAMADAN +L Q +RWYSQAGTP + V
Sbjct 483 MDLYFKRHDGKAVTCDDLRAAMADANDKDLSQFERWYSQAGTPHVTV 529
> pfa:MAL13P1.56 M1-family aminopeptidase (EC:3.4.11.-); K13725
M1-family aminopeptidase [EC:3.4.11.-]
Length=1085
Score = 388 bits (997), Expect = 1e-107, Method: Composition-based stats.
Identities = 194/365 (53%), Positives = 251/365 (68%), Gaps = 13/365 (3%)
Query 2 LKGLYVSGSALVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEG 61
L GLY S + +V+QCEA GFRRIT+F+DRPD++AKY V + A+K KYPVLLSNG+K E
Sbjct 304 LTGLYKSKNIIVSQCEATGFRRITFFIDRPDMMAKYDVTVTADKEKYPVLLSNGDKVNEF 363
Query 62 LVHGSPDRHFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTK-SGNEVALAVYSEPAQLHK 120
+ G RH A F DPH KP YLFA++AG+ + + TK + +V L V+SE + K
Sbjct 364 EIPGG--RHGARFNDPHLKPCYLFAVVAGDLKHLSATYITKYTKKKVELYVFSEEKYVSK 421
Query 121 LEWAMHSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQT 180
L+WA+ +K SM ++E++FG EYDL N+ VSDFN GAMENKGLNIFN LLA +
Sbjct 422 LQWALECLKKSMAFDEDYFGLEYDLSRLNLVAVSDFNVGAMENKGLNIFNANSLLASKKN 481
Query 181 STDDDFERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRI 240
S D + R+L VVGHEYFHN+TGNRVT+RDWFQLTLKEGLTV RE LF + R+
Sbjct 482 SIDFSYARILTVVGHEYFHNYTGNRVTLRDWFQLTLKEGLTVHRENLFSEEMTKTVTTRL 541
Query 241 KEVADLISRQFAEDDGPMAHPIRPESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRK 300
V L S QF ED P++HPIRPESY++M+NFYT TVYDKG+EV+R+Y T+LG ++K
Sbjct 542 SHVDLLRSVQFLEDSSPLSHPIRPESYVSMENFYTTTVYDKGSEVMRMYLTILGEEYYKK 601
Query 301 GMDMYFERHDNTAATCDDFRAAMADA-------NRINLDQMDRWYSQAGTPRLEVLRSEY 353
G D+Y +++D ATC+DF AM A N NL+Q W+SQ+GTP + +Y
Sbjct 602 GFDIYIKKNDGNTATCEDFNYAMEQAYKMKKADNSANLNQYLLWFSQSGTPHVSF---KY 658
Query 354 KEDAQ 358
DA+
Sbjct 659 NYDAE 663
> hsa:2028 ENPEP, APA, CD249, gp160; glutamyl aminopeptidase (aminopeptidase
A) (EC:3.4.11.7); K11141 glutamyl aminopeptidase
[EC:3.4.11.7]
Length=957
Score = 130 bits (328), Expect = 6e-30, Method: Compositional matrix adjust.
Identities = 107/349 (30%), Positives = 160/349 (45%), Gaps = 25/349 (7%)
Query 10 SALVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEGLVHGSPDR 69
S + T E R+ D P+ A Y + + K +Y L SN +E V R
Sbjct 216 SIVATDHEPTDARKSFPCFDEPNKKATYTISITHPK-EYGAL-SNMPVAKEESVDDKWTR 273
Query 70 HFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMHSVK 129
F P +YL +F ++ K + SG L +Y +P Q H E+A + K
Sbjct 274 --TTFEKSVPMSTYLVCFAVHQFDSV--KRISNSGK--PLTIYVQPEQKHTAEYAANITK 327
Query 130 VSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFERV 189
+ EE+F Y L + + DF GAMEN GL + T LL D + S + +RV
Sbjct 328 SVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDPKESASSNQQRV 387
Query 190 LAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKE---VADL 246
VV HE H W GN VT+ W L L EG F E F+G + ++++ + D+
Sbjct 388 ATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFE--FLGVNHAETDWQMRDQMLLEDV 445
Query 247 ISRQFAEDDGPM-AHPI-----RPESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRK 300
+ Q EDD M +HPI P+ ++ + Y KG+ ++R+ + F+K
Sbjct 446 LPVQ--EDDSLMSSHPIIVTVTTPDEITSV---FDGISYSKGSSILRMLEDWIKPENFQK 500
Query 301 GMDMYFERHDNTAATCDDFRAAMADANRINLDQ-MDRWYSQAGTPRLEV 348
G MY E++ A DF AA+ +A+R+ + + MD W Q G P L V
Sbjct 501 GCQMYLEKYQFKNAKTSDFWAALEEASRLPVKEVMDTWTRQMGYPVLNV 549
> hsa:9520 NPEPPS, AAP-S, MP100, PSA; aminopeptidase puromycin
sensitive (EC:3.4.11.14); K08776 puromycin-sensitive aminopeptidase
[EC:3.4.11.-]
Length=919
Score = 129 bits (324), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 107/376 (28%), Positives = 166/376 (44%), Gaps = 34/376 (9%)
Query 1 KLKGLYVSGS---------ALVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVL 51
K+KG Y S A VTQ EA RR D P + A + + L K + V
Sbjct 155 KMKGFYRSKYTTPSGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDR--VA 212
Query 52 LSNGNKTEEGLVHGSPDRHFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAV 111
LSN N + + F +YL A + GE+ D T+S + V + V
Sbjct 213 LSNMNVIDRKPYPDDENLVEVKFARTPVMSTYLVAFVVGEY----DFVETRSKDGVCVRV 268
Query 112 YSEPAQLHKLEWAMHSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNC 171
Y+ + + ++A+ ++ + +++F Y L ++ ++DF AGAMEN GL +
Sbjct 269 YTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRE 328
Query 172 TLLLADMQTSTDDDFERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFM-- 229
T LL D + S + V VVGHE H W GN VT+ W L L EG + E L +
Sbjct 329 TALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDH 388
Query 230 --------GTVMSAGVQRIKEVADLISRQFAEDDGPMAHPIRPESYMAMDNFYTATVYDK 281
+SA R +E+ L + E + HP +D + A Y K
Sbjct 389 CFPEYDIWTQFVSADYTRAQELDALDNSHPIEVS--VGHPSE------VDEIFDAISYSK 440
Query 282 GAEVVRIYHTLLGASGFRKGMDMYFERHDNTAATCDDFRAAMADANRINLDQ-MDRWYSQ 340
GA V+R+ H +G F+KGM+MY + A +D ++ +A+ + M+ W Q
Sbjct 441 GASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLENASGKPIAAVMNTWTKQ 500
Query 341 AGTPRLEVLRSEYKED 356
G P + V + ++D
Sbjct 501 MGFPLIYVEAEQVEDD 516
> mmu:19155 Npepps, AAP-S, MGC102199, MP100, Psa, R74825, goku;
aminopeptidase puromycin sensitive (EC:3.4.11.14); K08776
puromycin-sensitive aminopeptidase [EC:3.4.11.-]
Length=920
Score = 128 bits (322), Expect = 3e-29, Method: Compositional matrix adjust.
Identities = 107/376 (28%), Positives = 165/376 (43%), Gaps = 34/376 (9%)
Query 1 KLKGLYVSGS---------ALVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVL 51
K+KG Y S A VTQ EA RR D P + A + + L K + V
Sbjct 156 KMKGFYRSRYTTPAGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDR--VA 213
Query 52 LSNGNKTEEGLVHGSPDRHFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAV 111
LSN N + + F +YL A + GE+ D T+S + V + V
Sbjct 214 LSNMNVIDRKPYPDDENLVEVKFARTPVMSTYLVAFVVGEY----DFVETRSKDGVCVRV 269
Query 112 YSEPAQLHKLEWAMHSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNC 171
Y+ + + ++A+ ++ + +++F Y L ++ ++DF AGAMEN GL +
Sbjct 270 YTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRE 329
Query 172 TLLLADMQTSTDDDFERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFM-- 229
T LL D + S + V VVGHE H W GN VT+ W L L EG + E L +
Sbjct 330 TALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDH 389
Query 230 --------GTVMSAGVQRIKEVADLISRQFAEDDGPMAHPIRPESYMAMDNFYTATVYDK 281
+SA R +E+ L + E + HP +D + A Y K
Sbjct 390 CFPEYDIWTQFVSADYTRAQELDALDNSHPIEVS--VGHPSE------VDEIFDAISYSK 441
Query 282 GAEVVRIYHTLLGASGFRKGMDMYFERHDNTAATCDDFRAAMADANRINLDQ-MDRWYSQ 340
GA V+R+ H +G F+KGM+MY + A +D ++ A+ + M+ W Q
Sbjct 442 GASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLESASGKPIAAVMNTWTKQ 501
Query 341 AGTPRLEVLRSEYKED 356
G P + V + ++D
Sbjct 502 MGFPLIYVEAEQVEDD 517
> cel:T07F10.1 hypothetical protein
Length=988
Score = 127 bits (318), Expect = 8e-29, Method: Compositional matrix adjust.
Identities = 107/361 (29%), Positives = 166/361 (45%), Gaps = 30/361 (8%)
Query 8 SGSALVTQCEAEGFRRITYFLDRPDVLAKYKVR-LEANKAKYPVLLSNGNKTEEGLVHGS 66
S A VTQ E RR+ D P A + V + NK V +SNG E+ + G
Sbjct 217 SKMAAVTQMEPVYARRMVPCFDEPAYKATWTVTVIHPNKT---VAVSNG--IEDKVEDGQ 271
Query 67 PDRHFAVFTDPHPK-PSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAM 125
P + F P P+ SYL AI EF ++ TTKSG V V+S P + + +A+
Sbjct 272 PGFIISTF-KPTPRMSSYLLAIFISEFE--YNEATTKSG--VRFRVWSRPEEKNSTMYAV 326
Query 126 HSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDD 185
+ +++ E+++ + L ++ + DF+AGAMEN GL + + LL D + +
Sbjct 327 EAGVKCLEYYEKYYNISFPLPKQDMVALPDFSAGAMENWGLITYRESALLYDPRIYSGSQ 386
Query 186 FERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGT-VMSAGVQRIKE-- 242
RV V+ HE H W GN VT++ W L L EG E ++GT +S G R++E
Sbjct 387 KRRVAVVIAHELAHQWFGNLVTLKWWNDLWLNEGFATLVE--YLGTDEISDGNMRMREWF 444
Query 243 VADLISRQFAEDDGPMAHPI--RPESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRK 300
D + A D HP+ + + M + + + + YDKG V+ + +G F
Sbjct 445 TMDALWSALAADSVASTHPLTFKIDKAMEVLDSFDSVTYDKGGAVLAMVRKTIGEENFNT 504
Query 301 GMDMYFERHDNTAATCDDFRAAMAD----------ANRINLDQ-MDRWYSQAGTPRLEVL 349
G++ Y RH A + A+ + ++N+ + MD W Q G P L
Sbjct 505 GINHYLTRHQFDNADAGNLLTALGEKIPDSVMGPKGVKLNISEFMDPWTKQLGYPLLNAS 564
Query 350 R 350
R
Sbjct 565 R 565
> dre:407726 npepps, Psa, fb68d07, sb:cb848, wu:fb68d07; aminopeptidase
puromycin sensitive (EC:3.4.11.-); K08776 puromycin-sensitive
aminopeptidase [EC:3.4.11.-]
Length=872
Score = 126 bits (317), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 104/367 (28%), Positives = 162/367 (44%), Gaps = 17/367 (4%)
Query 1 KLKGLYVSGS--------ALVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLL 52
K+KG Y S A VTQ EA RR D P + A + + L K + V L
Sbjct 111 KMKGFYRSKYSSSGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDITLIVPKDR--VAL 168
Query 53 SNGNKTEEGLVHGSPDRHFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVY 112
SN N + F +YL A + GE+ D ++S + V + VY
Sbjct 169 SNMNVVDRKPYAEDQSLVEVKFATTPIMSTYLVAFVIGEY----DFVESQSSDGVTVRVY 224
Query 113 SEPAQLHKLEWAMHSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCT 172
+ + + ++A+ ++ + +++F Y L ++ ++DF AGAMEN GL + T
Sbjct 225 TPVGKAEQGKFALEVATKTLPFYKDYFSVPYPLPKIDLIAIADFAAGAMENWGLVTYRET 284
Query 173 LLLADMQTSTDDDFERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTV 232
LL D + S + V VVGHE H W GN VT+ W L L EG + E L +
Sbjct 285 ALLIDPKNSCASSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHC 344
Query 233 MSAGVQRIKEVADLISRQFAEDDGPMAHPIRPE--SYMAMDNFYTATVYDKGAEVVRIYH 290
+ V+ +R D +HPI + +D + A Y KGA V+R+ H
Sbjct 345 FPEYDIWTQFVSADYTRALDLDALDNSHPIEVDVGHPSEVDEIFDAISYSKGASVIRMLH 404
Query 291 TLLGASGFRKGMDMYFERHDNTAATCDDFRAAMADANRINLDQ-MDRWYSQAGTPRLEVL 349
+G FRKGM+ Y + + A+ +D + A+ + M+ W Q G P + V
Sbjct 405 NYIGDEDFRKGMNAYLLKFQHKNASTEDLWECLEQASGKPIAAVMNSWTKQMGFPIIVVD 464
Query 350 RSEYKED 356
+ ++ D
Sbjct 465 QEQHGSD 471
> ath:AT4G33090 APM1; APM1 (AMINOPEPTIDASE M1); aminopeptidase;
K08776 puromycin-sensitive aminopeptidase [EC:3.4.11.-]
Length=879
Score = 124 bits (312), Expect = 5e-28, Method: Compositional matrix adjust.
Identities = 105/355 (29%), Positives = 159/355 (44%), Gaps = 21/355 (5%)
Query 1 KLKGLYVS--------GSALVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLL 52
K+KG Y S + VTQ E RR D P A +K+ LE V L
Sbjct 114 KMKGFYRSTYEHNGEKKNMAVTQFEPADARRCFPCWDEPACKATFKITLEVPTDL--VAL 171
Query 53 SNGNKTEEGLVHGSPDRHFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVY 112
SN EE V+G + + + +YL AI+ G F + D + + + + VY
Sbjct 172 SNMPIMEEK-VNG--NLKIVSYQESPIMSTYLVAIVVGLFDYVEDH----TSDGIKVRVY 224
Query 113 SEPAQLHKLEWAMHSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCT 172
+ + + ++A+H ++ +E+F Y L ++ + DF AGAMEN GL + T
Sbjct 225 CQVGKADQGKFALHVGAKTLDLFKEYFAVPYPLPKMDMIAIPDFAAGAMENYGLVTYRET 284
Query 173 LLLADMQTSTDDDFERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTV 232
LL D Q S + +RV VV HE H W GN VT+ W L L EG + L ++
Sbjct 285 ALLYDEQHSAASNKQRVATVVAHELAHQWFGNLVTMEWWTHLWLNEGFATWVSYLATDSL 344
Query 233 MSAGVQRIKEVADLISRQFAEDDGPMAHPIRPESYMA--MDNFYTATVYDKGAEVVRIYH 290
+ + D + D +HPI E A +D + A Y KGA V+R+
Sbjct 345 FPEW-KIWTQFLDESTEGLRLDGLEESHPIEVEVNHAAEIDEIFDAISYRKGASVIRMLQ 403
Query 291 TLLGASGFRKGMDMYFERHDNTAATCDDFRAAMADANRINLDQ-MDRWYSQAGTP 344
+ LGA F+K + Y + H + A +D AA+ + +++ M W Q G P
Sbjct 404 SYLGAEVFQKSLAAYIKNHAYSNAKTEDLWAALEAGSGEPVNKLMSSWTKQKGYP 458
> cel:F49E8.3 pam-1; Puromycin-sensitive AMinopeptidase family
member (pam-1); K08776 puromycin-sensitive aminopeptidase [EC:3.4.11.-]
Length=948
Score = 122 bits (307), Expect = 1e-27, Method: Compositional matrix adjust.
Identities = 101/338 (29%), Positives = 149/338 (44%), Gaps = 10/338 (2%)
Query 14 TQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEGLVHGSPDRHFAV 73
TQ E+ R D P A + V LE + LSN N E +
Sbjct 203 TQFESTYARYAFPCFDEPIYKATFDVTLEVEN--HLTALSNMNVISETPTADGKRKAVTF 260
Query 74 FTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMHSVKVSMK 133
T P SYL A GE I + TKSG V + VY+ P + + ++++ +
Sbjct 261 ATSPK-MSSYLVAFAVGELEYISAQ--TKSG--VEMRVYTVPGKKEQGQYSLDLSVKCID 315
Query 134 WEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFERVLAVV 193
W E F +Y L ++ + DF+ GAMEN GL + LL D ++ RV VV
Sbjct 316 WYNEWFDIKYPLPKCDLIAIPDFSMGAMENWGLVTYREIALLVDPGVTSTRQKSRVALVV 375
Query 194 GHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEVADLISRQFAE 253
HE H W GN VT++ W L LKEG F E +F+G + + D ++
Sbjct 376 AHELAHLWFGNLVTMKWWTDLWLKEGFASFMEYMFVGANCPEFKIWLHFLNDELASGMGL 435
Query 254 DDGPMAHPIRPE--SYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKGMDMYFERHDN 311
D +HPI E + +D Y + Y K V R+ L F+KG+ +Y +R
Sbjct 436 DALRNSHPIEVEIDNPNELDEIYDSITYAKSNSVNRMLCYYLSEPVFQKGLRLYLKRFQY 495
Query 312 TAATCDDFRAAMADANRINLDQ-MDRWYSQAGTPRLEV 348
+ A D A+++A+ N+++ M W Q G P L+V
Sbjct 496 SNAVTQDLWTALSEASGQNVNELMSGWTQQMGFPVLKV 533
> dre:322533 anpep, fb64c05, wu:fb64c05, zgc:136771; alanyl (membrane)
aminopeptidase (EC:3.4.11.2); K11140 aminopeptidase
N [EC:3.4.11.2]
Length=965
Score = 121 bits (303), Expect = 4e-27, Method: Compositional matrix adjust.
Identities = 104/356 (29%), Positives = 161/356 (45%), Gaps = 33/356 (9%)
Query 14 TQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEGLVH-GSPDRHFA 72
TQ +A R+ D P + A + + L + V LSNG EE V
Sbjct 210 TQMQATDARKAFPCFDEPAMKAVFNIVLLHDPGT--VALSNGVVIEEIPVTVDGISLTKT 267
Query 73 VFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYS--EPAQLHKLEWAMHSVKV 130
F +YL A + EF I K +++ + +++ E ++ E+A+
Sbjct 268 TFAPTEKMSTYLLAFIVSEFTYIEQKL-----DDLQIRIFARKEAIDANQGEYALSVTGK 322
Query 131 SMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFERVL 190
+++ EE++ Y L + + DFNAGAMEN GL + T LL D + S++ + ERV+
Sbjct 323 ILRFFEEYYNSSYPLPKSDQIALPDFNAGAMENWGLITYRETALLYDEEMSSNGNKERVV 382
Query 191 AVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEVADL--IS 248
V+ HE H W GN VT+R W L L EG + E ++G + + IK++ L +
Sbjct 383 TVIAHELAHQWFGNLVTIRWWNDLWLNEGFASYVE--YLGADEAEPLWNIKDLIVLNDVH 440
Query 249 RQFAEDDGPMAHPI--------RPESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRK 300
R FA D +HP+ RPE + + Y KGA V+R+ L F +
Sbjct 441 RVFAIDALASSHPLSSKEEDVQRPEQ---ISEVFDTISYSKGASVLRMLSNFLSEDVFTQ 497
Query 301 GMDMYFE--RHDNTAAT--CDDFRAAMADAN----RINLDQMDRWYSQAGTPRLEV 348
G+ Y E + +NT T D + A+ + R D MDRW Q G P + +
Sbjct 498 GLRTYLEHFKFNNTVYTDLWDHLQMAVDETGTELPRSVKDIMDRWVLQMGFPVVTI 553
> mmu:13809 Enpep, 6030431M22Rik, APA, Bp-1/6C3, Ly-51, Ly51;
glutamyl aminopeptidase (EC:3.4.11.7); K11141 glutamyl aminopeptidase
[EC:3.4.11.7]
Length=945
Score = 119 bits (298), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 85/288 (29%), Positives = 130/288 (45%), Gaps = 23/288 (7%)
Query 72 AVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMHSVKVS 131
F P +YL F AI K ++SG L VY +P Q E+A + +
Sbjct 266 TTFVKSVPMSTYLVCFAVHRFTAIERK--SRSGK--PLKVYVQPNQKETAEYAANITQAV 321
Query 132 MKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFERVLA 191
+ E++F EY L + + DF GAMEN GL + T LL D S + +RV +
Sbjct 322 FDYFEDYFAMEYALPKLDKIAIPDFGTGAMENWGLVTYRETNLLYDPLLSASSNQQRVAS 381
Query 192 VVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEVADLISRQF 251
VV HE H W GN VT+ W L L EG F E L GV ++ ++S+
Sbjct 382 VVAHELVHQWFGNTVTMDWWDDLWLNEGFASFFEFL--------GVNHAEKDWQMLSQVL 433
Query 252 AEDDGPM--------AHP--IRPESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKG 301
ED P+ +HP + + + + + Y KGA ++R+ + F+KG
Sbjct 434 LEDVFPVQEDDSLMSSHPVVVTVSTPAEITSVFDGISYSKGASILRMLQDWITPEKFQKG 493
Query 302 MDMYFERHDNTAATCDDFRAAMADANRINLDQ-MDRWYSQAGTPRLEV 348
+Y ++ A DF ++ +A+ + + + MD W SQ G P + V
Sbjct 494 CQIYLKKFQFANAKTSDFWDSLQEASNLPVKEVMDTWTSQMGYPVVTV 541
> dre:504088 enpep, im:7152184, si:ch211-146m5.2; glutamyl aminopeptidase
(EC:3.4.11.7)
Length=951
Score = 117 bits (292), Expect = 9e-26, Method: Compositional matrix adjust.
Identities = 98/352 (27%), Positives = 159/352 (45%), Gaps = 17/352 (4%)
Query 7 VSGSALVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEGLVHGS 66
V+ T E R+ D P+ A Y + + + + Y L + + E L S
Sbjct 204 VTKKIAATDHEPTDARKSFPCFDEPNKKATYTISI-THDSTYKALSNMPVEKTEKL---S 259
Query 67 PDRHFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMH 126
+ F +YL +F + T+K G + L +Y++P Q+ +A
Sbjct 260 EQKTKTSFMKSVKMSTYLVCFAVHQFDFVER--TSKRG--IPLRIYAQPLQISTAAYAAD 315
Query 127 SVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDF 186
+V + EE+F EY + + + DF GAMEN GL + T LL D + S+ +
Sbjct 316 VTQVIFDYFEEYFDMEYSIQKLDKIAIPDFGTGAMENWGLITYRETNLLFDEKESSSVNK 375
Query 187 ERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSA---GVQRIKEV 243
+RV +V+ HE H W GN VT+ W L L EG F E ++G + G++ + +
Sbjct 376 QRVASVIAHELVHQWFGNIVTMDWWDDLWLNEGFASFFE--YIGVEEAEHDWGMRDVMLI 433
Query 244 ADLISRQFAEDDGPMAHPIRPE--SYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKG 301
D + +D +HPI + S + + + A Y+KGA ++R+ LLG FR G
Sbjct 434 ND-VYPVMVDDALLSSHPIIVDVSSPAEITSVFDAISYNKGASILRMLEDLLGRETFRDG 492
Query 302 MDMYFERHDNTAATCDDFRAAMADANRINL-DQMDRWYSQAGTPRLEVLRSE 352
Y + + A DF A+AD + + + D MD W Q G P L + ++
Sbjct 493 CRRYLKTYLFQNAKTSDFWKALADESGLPVADIMDTWTKQMGYPVLSLTNTD 544
> sce:YHR047C AAP1, AAP1'; Aap1p (EC:3.4.11.-)
Length=856
Score = 115 bits (289), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 92/338 (27%), Positives = 147/338 (43%), Gaps = 13/338 (3%)
Query 14 TQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEGLVHGSPDRHFAV 73
TQ EA RR D P++ A + V L + + LSN + E + G + +
Sbjct 129 TQMEATDARRAFPCFDEPNLKATFAVTLVSES--FLTHLSNMDVRNETIKEG---KKYTT 183
Query 74 FTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMHSVKVSMK 133
F +YL A + + ++ + + + VYS P ++A + +++
Sbjct 184 FNTTPKMSTYLVAFIVADL-----RYVESNNFRIPVRVYSTPGDEKFGQFAANLAARTLR 238
Query 134 WEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFERVLAVV 193
+ E+ F EY L ++ V +F+AGAMEN GL + LL D++ S+ D +RV V+
Sbjct 239 FFEDTFNIEYPLPKMDMVAVHEFSAGAMENWGLVTYRVIDLLLDIENSSLDRIQRVAEVI 298
Query 194 GHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEVADLISRQFAE 253
HE H W GN VT+ W L L EG + + V D + R
Sbjct 299 QHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNKFQPEWKVWEQYVTDNLQRALNL 358
Query 254 DDGPMAHPIRPESYMA--MDNFYTATVYDKGAEVVRIYHTLLGASGFRKGMDMYFERHDN 311
D +HPI A ++ + A Y KG+ ++R+ LG F KG+ Y +
Sbjct 359 DSLRSSHPIEVPVNNADEINQIFDAISYSKGSSLLRMISKWLGEETFIKGVSQYLNKFKY 418
Query 312 TAATCDDFRAAMADANRINL-DQMDRWYSQAGTPRLEV 348
A D A+ADA+ ++ M+ W + G P L V
Sbjct 419 GNAKTGDLWDALADASGKDVCSVMNIWTKRVGFPVLSV 456
> mmu:16790 Anpep, Apn, Cd13, Lap-1, Lap1, P150; alanyl (membrane)
aminopeptidase (EC:3.4.11.2); K11140 aminopeptidase N [EC:3.4.11.2]
Length=966
Score = 114 bits (285), Expect = 5e-25, Method: Compositional matrix adjust.
Identities = 99/362 (27%), Positives = 160/362 (44%), Gaps = 44/362 (12%)
Query 14 TQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYP---VLLSNGNKTEEGLVHGSPDRH 70
TQ +A R+ D P + A + + L YP + LSN E P+
Sbjct 210 TQMQAADARKSFPCFDEPAMKAMFNITL-----IYPNNLIALSNMLPKES---KPYPEDP 261
Query 71 FAVFTDPHPKP---SYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLH--KLEWAM 125
T+ H P +YL A + EF I ++ S N V + +++ P+ + + ++A+
Sbjct 262 SCTMTEFHSTPKMSTYLLAYIVSEFKNI----SSVSANGVQIGIWARPSAIDEGQGDYAL 317
Query 126 HSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDD 185
+ + + +H+ Y L + + DFNAGAMEN GL + + L+ D Q+S+ +
Sbjct 318 NVTGPILNFFAQHYNTSYPLPKSDQIALPDFNAGAMENWGLVTYRESSLVFDSQSSSISN 377
Query 186 FERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEVAD 245
ERV+ V+ HE H W GN VTV W L L EG + E ++G + +K++
Sbjct 378 KERVVTVIAHELAHQWFGNLVTVAWWNDLWLNEGFASYVE--YLGADYAEPTWNLKDLMV 435
Query 246 L--ISRQFAEDDGPMAHPIR--------PESYMAMDNFYTATVYDKGAEVVRIYHTLLGA 295
L + R A D +HP+ P+ M + + + Y KGA V+R+ + L
Sbjct 436 LNDVYRVMAVDALASSHPLSSPADEIKTPDQIMEL---FDSITYSKGASVIRMLSSFLTE 492
Query 296 SGFRKGMDMYFERHDNTAATCDDFRAAMADA-NRINLDQ--------MDRWYSQAGTPRL 346
F+KG+ Y + + D + A N+ Q MDRW Q G P +
Sbjct 493 DLFKKGLSSYLHTYQYSNTVYLDLWEHLQKAVNQQTAVQPPATVRTIMDRWILQMGFPVI 552
Query 347 EV 348
V
Sbjct 553 TV 554
> sce:YKL157W APE2, LAP1, YKL158W; Aminopeptidase yscII; may have
a role in obtaining leucine from dipeptide substrates; sequence
coordinates have changed since RT-PCR analysis showed
that the adjacent ORF YKL158W comprises the 5' exon of APE2/YKL157W;
K13721 aminopeptidase 2 [EC:3.4.11.-]
Length=935
Score = 114 bits (284), Expect = 8e-25, Method: Compositional matrix adjust.
Identities = 94/340 (27%), Positives = 144/340 (42%), Gaps = 17/340 (5%)
Query 14 TQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVL--LSNGNKTEEGLVHGSPDRHF 71
TQ E RR D P++ A + + L ++ P L LSN + E + G +
Sbjct 225 TQMEPTDARRAFPCFDEPNLKASFAITLVSD----PSLTHLSNMDVKNEYVKDG---KKV 277
Query 72 AVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMHSVKVS 131
+F +YL A + E K+ + + VY+ P ++A +
Sbjct 278 TLFNTTPKMSTYLVAFIVAEL-----KYVESKNFRIPVRVYATPGNEKHGQFAADLTAKT 332
Query 132 MKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFERVLA 191
+ + E+ FG +Y L + V +F+AGAMEN GL + LL D ST D +RV
Sbjct 333 LAFFEKTFGIQYPLPKMDNVAVHEFSAGAMENWGLVTYRVVDLLLDKDNSTLDRIQRVAE 392
Query 192 VVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEVADLISRQF 251
VV HE H W GN VT+ W L L EG + + V D +
Sbjct 393 VVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNEFQPEWKVWEQYVTDTLQHAL 452
Query 252 AEDDGPMAHPIRPESYMA--MDNFYTATVYDKGAEVVRIYHTLLGASGFRKGMDMYFERH 309
+ D +HPI A ++ + A Y KGA ++R+ LG F KG+ Y +
Sbjct 453 SLDSLRSSHPIEVPVKKADEINQIFDAISYSKGASLLRMISKWLGEETFIKGVSQYLNKF 512
Query 310 DNTAATCDDFRAAMADANRINLDQ-MDRWYSQAGTPRLEV 348
A +D A+ADA+ ++ M+ W + G P + V
Sbjct 513 KYGNAKTEDLWDALADASGKDVRSVMNIWTKKVGFPVISV 552
> mmu:240028 Lnpep, 2010309L07Rik, 4732490P18Rik, CAP, IRAP, PLAP,
gp160, vp165; leucyl/cystinyl aminopeptidase (EC:3.4.11.3);
K01257 cystinyl aminopeptidase [EC:3.4.11.3]
Length=1025
Score = 110 bits (274), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 91/350 (26%), Positives = 151/350 (43%), Gaps = 31/350 (8%)
Query 14 TQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNK-----TEEGLVHGSPD 68
TQ E R D P A + +++ N+ + LSN K EEGL+
Sbjct 292 TQFEPLAARSAFPCFDEPAFKATFIIKITRNE--HHTALSNMPKKSSVPAEEGLIQDE-- 347
Query 69 RHFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMHSV 128
F++ +YL A + GE + ++ N ++VY+ P ++ ++ A+ +
Sbjct 348 -----FSESVKMSTYLVAFIVGEMRNL-----SQDVNGTLVSVYAVPEKIGQVHHALDTT 397
Query 129 KVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFER 188
+++ + +F +Y L ++ + DF AGAMEN GL F LL D TS+ D +
Sbjct 398 IKLLEFYQTYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDNATSSVADRKL 457
Query 189 VLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEVADLIS 248
V ++ HE H W GN VT++ W L L EG F E + + + + D +
Sbjct 458 VTKIIAHELAHQWFGNLVTMQWWNDLWLNEGFATFMEYFSVEKIF----KELNSYEDFLD 513
Query 249 RQFA---EDDGPMAHPIRP--ESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKGMD 303
+F +D +HPI +S ++ + + Y KGA ++ + + L FR +
Sbjct 514 ARFKTMRKDSLNSSHPISSSVQSSEQIEEMFDSLSYFKGASLLLMLKSYLSEDVFRHAVI 573
Query 304 MYFERHDNTAATCDDFRAAMADANRINLD---QMDRWYSQAGTPRLEVLR 350
+Y H A DD + + LD M W Q G P + V R
Sbjct 574 LYLHNHSYAAIQSDDLWDSFNEVTDKTLDVKKMMKTWTLQKGFPLVTVQR 623
> dre:555317 aminopeptidase N-like
Length=956
Score = 107 bits (266), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 94/355 (26%), Positives = 154/355 (43%), Gaps = 28/355 (7%)
Query 14 TQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEGLVHGSPDRHFAV 73
TQ + R D P + A + + L V L+NG +T + +
Sbjct 205 TQMQPTAARTAFPCFDEPSMKAVFHLTLIHPPGT--VALANGMETGTENITIENQQVLQT 262
Query 74 FTDPHPKPS-YLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLE--WAMHSVKV 130
+P K S YL A + EF +I+ N++ + ++ + E +A++
Sbjct 263 RFEPTEKMSTYLLAFVISEFPSIQSPL---GANKILVRIWGRREAIENGEGDYALNVTFP 319
Query 131 SMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFERVL 190
+K+ E ++ Y L + + DF+AGAMEN GL + T L + + S+ +D E V+
Sbjct 320 VLKYLESYYNTTYPLSKSDQIALPDFSAGAMENWGLVTYRETFLFYEPKVSSHEDKEGVI 379
Query 191 AVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEVADL--IS 248
V+ HE H W GN VT+R W L L EG + ++ + IKE+ L +
Sbjct 380 TVISHELAHMWFGNLVTMRWWNDLWLNEGFASYVS--YLAADYAEPTWNIKELMVLQQVY 437
Query 249 RQFAEDDGPMAHPIRP-----ESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKGMD 303
R F D +HP+ + ++ + A Y KGA V+R+ L S F KG+
Sbjct 438 RAFTVDALVSSHPLSSREDAVNTPQQIEELFDAVTYSKGAAVLRMLSEFLSESVFAKGLH 497
Query 304 MYFERHDNTAATCDDF-----RAAMADANRINL-----DQMDRWYSQAGTPRLEV 348
Y + H + D A +D N ++L + M+RW QAG P + +
Sbjct 498 NYLQEHAYSNTVYTDLWKKLQEVADSDGN-VHLPASIEEIMNRWILQAGFPVVTI 551
> hsa:4012 LNPEP, CAP, IRAP, P-LAP, PLAP; leucyl/cystinyl aminopeptidase
(EC:3.4.11.3); K01257 cystinyl aminopeptidase [EC:3.4.11.3]
Length=1025
Score = 106 bits (265), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 84/344 (24%), Positives = 151/344 (43%), Gaps = 23/344 (6%)
Query 14 TQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKT----EEGLVHGSPDR 69
TQ E R D P A + +++ ++ +Y L + K+ ++GLV
Sbjct 292 TQFEPLAARSAFPCFDEPAFKATFIIKIIRDE-QYTALSNMPKKSSVVLDDGLVQDE--- 347
Query 70 HFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMHSVK 129
F++ +YL A + GE K ++ N +++Y+ P ++ ++ +A+ +
Sbjct 348 ----FSESVKMSTYLVAFIVGEM-----KNLSQDVNGTLVSIYAVPEKIGQVHYALETTV 398
Query 130 VSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFERV 189
+++ + +F +Y L ++ + DF AGAMEN GL F LL D TS+ D + V
Sbjct 399 KLLEFFQNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDSNTSSMADRKLV 458
Query 190 LAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEVADLISR 249
++ HE H W GN VT++ W L L EG F E + + + ++ D +
Sbjct 459 TKIIAHELAHQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIFKE-LSSYEDFLDARFK 517
Query 250 QFAEDDGPMAHPIRP--ESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKGMDMYFE 307
+D +HPI +S ++ + + Y KG+ ++ + T L F+ + +Y
Sbjct 518 TMKKDSLNSSHPISSSVQSSEQIEEMFDSLSYFKGSSLLLMLKTYLSEDVFQHAVVLYLH 577
Query 308 RHDNTAATCDDFRAAMADANRINLD---QMDRWYSQAGTPRLEV 348
H + DD + + LD M W Q G P + V
Sbjct 578 NHSYASIQSDDLWDSFNEVTNQTLDVKRMMKTWTLQKGFPLVTV 621
> xla:379719 hypothetical protein MGC69084
Length=997
Score = 105 bits (262), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 91/353 (25%), Positives = 154/353 (43%), Gaps = 28/353 (7%)
Query 10 SALVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNK-----TEEGLVH 64
S TQ E R+ D P + +++ + K + + LSN K T +GL+
Sbjct 283 SLAATQFEPTAARKAFPCFDEPAFKSTFQINI-IRKDESMISLSNMPKAKTSTTNDGLL- 340
Query 65 GSPDRHFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWA 124
F+ +YL A + G+ K TT+ N+ ++VY+ P + ++++A
Sbjct 341 ------LDEFSTSVKMSTYLVAFIVGDI-----KNTTRETNDTLVSVYTVPEKTDQVKYA 389
Query 125 MHSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDD 184
+ S + + ++G +Y L+ ++ + DF A AMEN GL F T LL + +S+
Sbjct 390 LDSAVKLLDFYSNYYGIKYPLEKLDLVAIPDFQAAAMENWGLITFRETSLLYNEDSSSIK 449
Query 185 DFERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEVA 244
D + + + HE H W GN VT+ W L L EG + E +V S + E +
Sbjct 450 DKQTITIAIAHELTHQWFGNLVTMEWWNDLWLNEGFATYMEYF---SVSSLFPELNSENS 506
Query 245 DLISRQFA--EDDGPMAHPIRPE--SYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRK 300
L R A +D +HPI + S ++ + Y KGA ++ + T L F
Sbjct 507 FLKMRFMALKKDSLNASHPISTDIRSPEQIEEMFNDLSYIKGASILLMLKTFLSEDMFHL 566
Query 301 GMDMYFERHDNTAATCDDFRAAMADANRIN---LDQMDRWYSQAGTPRLEVLR 350
+ Y + H + T D ++ + N + M W +AG P + LR
Sbjct 567 SIRSYLQSHQYGSTTSDSLWDSLNVVTKENPNVKNMMKTWTQKAGYPLVTALR 619
> dre:555478 aminopeptidase N-like; K11140 aminopeptidase N [EC:3.4.11.2]
Length=960
Score = 104 bits (260), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 92/356 (25%), Positives = 159/356 (44%), Gaps = 29/356 (8%)
Query 13 VTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEGLVHGSPDRHFA 72
+TQ +A R+ D P + A + + L ++ + S +TE+ ++ P
Sbjct 201 ITQMQATYARKAFPCFDEPGMKAVFNIILIHDRGMTALSNSQEIRTEDVIIDEMPVTR-T 259
Query 73 VFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMHSVKVSM 132
F +YL A + +F+ I ++ K+G V + + + ++A+ + +
Sbjct 260 TFEPTARMSTYLVAFVVSDFSYINNE--DKAGVLVRIWARKKAIDDGQGDYALSITQPIL 317
Query 133 KWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFERVLAV 192
++ E ++ Y L + + DFN+GAMEN GL + T LL D QTS + + +R+ V
Sbjct 318 EFFESYYNTSYPLSKSDQVALPDFNSGAMENWGLVTYRETALLYDPQTSANGNKQRIATV 377
Query 193 VGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEVADL--ISRQ 250
V HE H W GN VT++ W L L EG + E ++G + IK+ L + R
Sbjct 378 VSHELAHMWFGNLVTLKWWNDLWLNEGFASYVE--YLGADHAEPTWNIKDQIILYDMQRA 435
Query 251 FAEDDGPMAHPI-RPESYM----AMDNFYTATVYDKGAEVVRIYHTLLGASGFRKGMDMY 305
FA D +HP+ R E + + ++ Y KGA V+++ L F KG+ Y
Sbjct 436 FAVDSLTSSHPLSRKEEEVNTPAEISEMFSTISYSKGAAVLKMLSEFLTEPVFAKGLSNY 495
Query 306 FERHDNTAATCDDFRAAMADANRINLDQ-------------MDRWYSQAGTPRLEV 348
++ ++ D + D + +LDQ M RW Q G P + +
Sbjct 496 LKQFAFGSSVHSD----LWDHLQKSLDQAPGMKLPRSIHEIMSRWILQMGFPVITI 547
> hsa:290 ANPEP, APN, CD13, GP150, LAP1, P150, PEPN; alanyl (membrane)
aminopeptidase (EC:3.4.11.2); K11140 aminopeptidase
N [EC:3.4.11.2]
Length=967
Score = 104 bits (260), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 95/356 (26%), Positives = 154/356 (43%), Gaps = 30/356 (8%)
Query 13 VTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEGLVHGSPDRHFA 72
TQ +A R+ D P + A++ + L K L + N +G P+
Sbjct 209 TTQMQAADARKSFPCFDEPAMKAEFNITLIHPKD----LTALSNMLPKGPSTPLPEDPNW 264
Query 73 VFTDPHPKP---SYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKL--EWAMHS 127
T+ H P +YL A + EF D ++ N V + +++ P+ + ++A++
Sbjct 265 NVTEFHTTPKMSTYLLAFIVSEF----DYVEKQASNGVLIRIWARPSAIAAGHGDYALNV 320
Query 128 VKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFE 187
+ + H+ Y L + + DFNAGAMEN GL + LL D +S+ + E
Sbjct 321 TGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKE 380
Query 188 RVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEVADL- 246
RV+ V+ HE H W GN VT+ W L L EG + E ++G + +K++ L
Sbjct 381 RVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVE--YLGADYAEPTWNLKDLMVLN 438
Query 247 -ISRQFAEDDGPMAHPIR-PESYM----AMDNFYTATVYDKGAEVVRIYHTLLGASGFRK 300
+ R A D +HP+ P S + + + A Y KGA V+R+ + L F++
Sbjct 439 DVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQ 498
Query 301 GMDMY---FERHDNTAATCDDFRAAMADANRINL-----DQMDRWYSQAGTPRLEV 348
G+ Y F + D + I L D M+RW Q G P + V
Sbjct 499 GLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPVITV 554
> dre:322814 fb73h12, wu:fb73h12; zgc:66103 (EC:3.4.11.3); K01257
cystinyl aminopeptidase [EC:3.4.11.3]
Length=1003
Score = 103 bits (258), Expect = 7e-22, Method: Compositional matrix adjust.
Identities = 92/352 (26%), Positives = 160/352 (45%), Gaps = 33/352 (9%)
Query 14 TQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNK------TEEGLVHGSP 67
TQ E R+ D P + + V++ +AKY + LSN K E GL
Sbjct 272 TQFEPLAARKAFPCFDEPAFKSTFVVKM-TREAKY-ISLSNMPKIKTTDLNENGLQEDE- 328
Query 68 DRHFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMHS 127
F +YL A + EF++ +K+ ++ ++VY+ P + ++ +A+ +
Sbjct 329 ------FESSVKMSTYLVAFIVAEFSS-----HSKNVSKTTVSVYAVPDKKDQVHYALET 377
Query 128 VKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFE 187
+K+ F EY L ++ + DF AGAMEN GL F T LL Q+S D +
Sbjct 378 ACKLLKFYNTFFEIEYPLSKLDLVAIPDFLAGAMENWGLITFRETTLLVGNQSSRFDK-Q 436
Query 188 RVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEVADLI 247
V +V+ HE H W GN VT+R W L L EG + + + + V I E ++
Sbjct 437 LVTSVIAHELAHQWFGNLVTMRWWNDLWLNEGFATYMQYMSIENVFPDLDIDI-EFLNVR 495
Query 248 SRQFAEDDGPMAHPIR-----PESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKGM 302
+ A+D +HP+ PE ++ + + Y+KGA ++ + + L F KG+
Sbjct 496 FKALAKDALNSSHPVSTFVSTPEQ---VEEMFDSVSYEKGASILLMLNATLRDGEFHKGV 552
Query 303 DMYFERHDNTAATCDDFRAAMADANRINLD---QMDRWYSQAGTPRLEVLRS 351
Y + ++ + D +++ ++ +L+ M+ W G P + V R+
Sbjct 553 IEYLQNYNLSNTESKDLWNSLSQVSKQSLNVSEMMNTWTVHKGFPLVTVKRN 604
> xla:495293 lnpep; leucyl/cystinyl aminopeptidase (EC:3.4.11.3);
K01257 cystinyl aminopeptidase [EC:3.4.11.3]
Length=1024
Score = 103 bits (256), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 90/351 (25%), Positives = 152/351 (43%), Gaps = 24/351 (6%)
Query 10 SALVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSN-----GNKTEEGLVH 64
S TQ E R+ D P + +++ + N + LSN +KT +GL+
Sbjct 285 SLAATQFEPLAARKAFPCFDEPAFKSTFQINIIRNDESM-ISLSNMPKAKTSKTSDGLLQ 343
Query 65 GSPDRHFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWA 124
+ T YL A + G+ K TT+ N+ ++VY+ P + ++++A
Sbjct 344 DEYSTSVRMST-------YLVAFIVGDI-----KNTTQKTNDTLVSVYAVPDKTDQVKYA 391
Query 125 MHSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDD 184
+ S + + ++G EY L+ ++ + DF AGAMEN GL F T LL +S+ +
Sbjct 392 LDSTVKLLDFYSNYYGIEYPLEKLDLVAIPDFQAGAMENWGLITFRETTLLYKENSSSIE 451
Query 185 DFERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEVA 244
D + + V+ HE H W GN VT+ W L L EG + E + +V +
Sbjct 452 DKQSITTVIAHELAHQWFGNLVTMEWWNDLWLNEGFATYMEYFSVSSVFPE-LNSDNSFL 510
Query 245 DLISRQFAEDDGPMAHPIRPE--SYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKGM 302
+ +D +HPI + S ++ + Y KGA ++ + +LL F +
Sbjct 511 KMRFMALQKDSLNSSHPISTDVRSPEQIEEMFDDLSYIKGASILLMLKSLLLEDVFHLCI 570
Query 303 DMYFERHDNTAATCD---DFRAAMADANRINLDQMDRWYSQAGTPRLEVLR 350
Y + H+ + T D D + N + M W +AG P + LR
Sbjct 571 RGYLKSHEYGSTTSDSLWDSLNVVTGGNPNVKNMMKTWTQKAGYPLVTALR 621
> xla:495476 anpep; alanyl (membrane) aminopeptidase; K11140 aminopeptidase
N [EC:3.4.11.2]
Length=963
Score = 102 bits (255), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 103/356 (28%), Positives = 158/356 (44%), Gaps = 33/356 (9%)
Query 14 TQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEGLVHGSPDRHFAV 73
TQ +A R+ D P + A + + L K K P + + E G D
Sbjct 207 TQMQAPDARKAFPCFDEPAMKATFSITL---KYKKPYKAMSNMQDIETKTEG--DWMITK 261
Query 74 FTDPHPKPS-YLFAILAGEFAAI-RDKFTTKSGNEV---ALAVYSEPAQLHKLEWAMHSV 128
F D PK S YL A + EF +I D T +G ++ A+ E + E+A+
Sbjct 262 F-DKTPKMSTYLVAFIVSEFESIGNDGNDTVTGVKIWGRKKAIVDE----KQGEYALSVT 316
Query 129 KVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFER 188
K + + E+++ Y L + + DF+AGAMEN GL + T LL D S+ + ER
Sbjct 317 KPILDFFEKYYRTPYPLPKSDQVALPDFSAGAMENWGLVTYRETALLFDENVSSIGNKER 376
Query 189 VLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEVADL-- 246
V+ VV HE H W GN VT+R W L L EG + E ++G + IK++ L
Sbjct 377 VVTVVAHELAHQWFGNLVTIRWWNDLWLNEGFASYVE--YLGADEAEPDWNIKDLIVLND 434
Query 247 ISRQFAEDDGPMAHPIRPE-----SYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKG 301
+ R A D +HP+ + S + + + Y KGA V+R+ L F G
Sbjct 435 VHRVMAVDALASSHPLTSKEEEVNSPSEISALFDSIAYSKGASVIRMLSEFLTEPLFVNG 494
Query 302 MDMYFE--RHDNTAAT--CDDFRAAMADANRINL-----DQMDRWYSQAGTPRLEV 348
+ Y + +DNT + + A+ + + L D MD W Q G P +++
Sbjct 495 LASYLKGFEYDNTVYSDLWTHLQMAVDNQTAVQLPLPIKDIMDTWVLQMGFPVVKI 550
> hsa:51752 ERAP1, A-LAP, ALAP, APPILS, ARTS-1, ARTS1, ERAAP,
ERAAP1, KIAA0525, PILS-AP, PILSAP; endoplasmic reticulum aminopeptidase
1; K09604 adipocyte-derived leucine aminopeptidase
[EC:3.4.11.-]
Length=941
Score = 101 bits (251), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 80/317 (25%), Positives = 138/317 (43%), Gaps = 19/317 (5%)
Query 14 TQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVL---LSNGNKTEEGLVHGSPDRH 70
TQ E R D P A + +++ + L EGL+ + H
Sbjct 180 TQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLI----EDH 235
Query 71 FAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMHSVKV 130
F V +YL A + +F ++ TKSG V ++VY+ P ++++ ++A+ +
Sbjct 236 FDVTVK---MSTYLVAFIISDFESVSK--ITKSG--VKVSVYAVPDKINQADYALDAAVT 288
Query 131 SMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFERVL 190
+++ E++F Y L ++A + DF +GAMEN GL + + LL D + S+ +
Sbjct 289 LLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGIT 348
Query 191 AVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTV---MSAGVQRIKEVADLI 247
V HE H W GN VT+ W L L EG F E + + + G + D +
Sbjct 349 MTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAM 408
Query 248 SRQFAEDDGPMAHPIRPESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKGMDMYFE 307
P++ P+ E+ + + YDKGA ++ + L A F+ G+ Y +
Sbjct 409 EVDALNSSHPVSTPV--ENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQ 466
Query 308 RHDNTAATCDDFRAAMA 324
+H +D +MA
Sbjct 467 KHSYKNTKNEDLWDSMA 483
> mmu:237553 Trhde, 9330155P21Rik, MGC40831; TRH-degrading enzyme
(EC:3.4.19.6); K01306 pyroglutamyl-peptidase II [EC:3.4.19.6]
Length=1025
Score = 98.6 bits (244), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 76/270 (28%), Positives = 130/270 (48%), Gaps = 17/270 (6%)
Query 100 TTKSGNEVALAVYSEPAQLHKL--EWAMHSVKVSMKWEEEHFGREYDLDIFNVACVSDFN 157
TTKSG V + +Y+ P + + ++A+H K +++ E++F Y L ++ V
Sbjct 346 TTKSG--VVVRLYARPDAIRRGSGDYALHITKRLIEFYEDYFKVPYSLPKLDLLAVPKHP 403
Query 158 AGAMENKGLNIFNCTLLLADMQTSTDDDFERVLAVVGHEYFHNWTGNRVTVRDWFQLTLK 217
AMEN GL+IF +L D S+ V V+ HE H W G+ VT W + LK
Sbjct 404 YAAMENWGLSIFVEQRILLDPSVSSISYLLDVTMVIVHEICHQWFGDLVTPVWWEDVWLK 463
Query 218 EGLTVFREQLFMGT---VMSAGVQRIKEVADLISRQFAEDDGPMAHPIRPESYMA--MDN 272
EG + E F+GT + +++ + + D++ D +HP+ E A +D
Sbjct 464 EGFAHYFE--FVGTDYLYPAWNMEKQRFLTDVLHEVMLLDGLASSHPVSQEVLRATDIDR 521
Query 273 FYTATVYDKGAEVVRIYHTLLGASGFRKGMDMYFERHDNTAATCDDFRAAMADANR---- 328
+ Y KGA ++R+ +G S F++G+ Y H A +D +++A R
Sbjct 522 VFDWIAYKKGAALIRMLANFMGHSVFQRGLQDYLTIHKYGNAARNDLWNTLSEALRRNGK 581
Query 329 -INLDQ-MDRWYSQAGTPRLEVLRSEYKED 356
+N+ + MD+W Q G P + +L + E+
Sbjct 582 YVNIQEVMDQWTLQMGYPVITILGNTTAEN 611
> hsa:29953 TRHDE, FLJ22381, PAP-II, PGPEP2, TRH-DE; thyrotropin-releasing
hormone degrading enzyme (EC:3.4.19.6); K01306
pyroglutamyl-peptidase II [EC:3.4.19.6]
Length=1024
Score = 97.1 bits (240), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 76/270 (28%), Positives = 131/270 (48%), Gaps = 17/270 (6%)
Query 100 TTKSGNEVALAVYSEPAQLHKL--EWAMHSVKVSMKWEEEHFGREYDLDIFNVACVSDFN 157
TTKSG V + +Y+ P + + ++A+H K +++ E++F Y L ++ V
Sbjct 345 TTKSG--VVVRLYARPDAIRRGSGDYALHITKRLIEFYEDYFKVPYSLPKLDLLAVPKHP 402
Query 158 AGAMENKGLNIFNCTLLLADMQTSTDDDFERVLAVVGHEYFHNWTGNRVTVRDWFQLTLK 217
AMEN GL+IF +L D S+ V V+ HE H W G+ VT W + LK
Sbjct 403 YAAMENWGLSIFVEQRILLDPSVSSISYLLDVTMVIVHEICHQWFGDLVTPVWWEDVWLK 462
Query 218 EGLTVFREQLFMGT-VMSAG--VQRIKEVADLISRQFAEDDGPMAHPIRPESYMA--MDN 272
EG + E F+GT + G +++ + + D++ D +HP+ E A +D
Sbjct 463 EGFAHYFE--FVGTDYLYPGWNMEKQRFLTDVLHEVMLLDGLASSHPVSQEVLQATDIDR 520
Query 273 FYTATVYDKGAEVVRIYHTLLGASGFRKGMDMYFERHDNTAATCDDFRAAMADANR---- 328
+ Y KGA ++R+ +G S F++G+ Y H A +D +++A +
Sbjct 521 VFDWIAYKKGAALIRMLANFMGHSVFQRGLQDYLTIHKYGNAARNDLWNTLSEALKRNGK 580
Query 329 -INLDQ-MDRWYSQAGTPRLEVLRSEYKED 356
+N+ + MD+W Q G P + +L + E+
Sbjct 581 YVNIQEVMDQWTLQMGYPVITILGNTTAEN 610
> cel:Y67D8C.9 hypothetical protein
Length=1087
Score = 96.7 bits (239), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 94/364 (25%), Positives = 157/364 (43%), Gaps = 27/364 (7%)
Query 7 VSGSALVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEGLVHGS 66
+ ++ T+ E R D P V A + + + NK KY VL SN E H S
Sbjct 247 LKATSFTTKFEPTLARAFFPCWDEPGVKATFNISVRHNK-KYTVL-SNMPPVESH-DHKS 303
Query 67 PDRHF--AVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWA 124
+ F VF P +YL A GEF K +++ + + V++ P + +++
Sbjct 304 WEDQFKTTVFQTTPPMSTYLLAFAIGEFV----KLESRTERGIPVTVWTYPEDVMSMKFT 359
Query 125 MHSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNC-----TLLLADMQ 179
+ V E+ Y L ++ +F+ G MEN GL +F T + D
Sbjct 360 LEYAPVIFDRLEDALEIPYPLPKVDLIAARNFHVGGMENWGLVVFEFASIAYTPPITDHV 419
Query 180 TSTDDDFE---RVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGT--VMS 234
T D R+ ++ HE H W GN VT+RDW +L L EG F M T ++
Sbjct 420 NETVDRMYNEFRIGKLIAHEAAHQWFGNLVTMRDWSELFLNEGFATFYVYEMMSTERPVT 479
Query 235 AGVQRIKEVADLISRQFAEDDG-PMAHPIRPESYMAMDNFYTATVYDKGAEVVRIYHTLL 293
A + +A LI Q ED + + ES + +F+ +Y KG ++R+ L+
Sbjct 480 AQFEYYDSLASLILAQSEEDHRLSLVRELATESQVE-SSFHPTNLYTKGCVLIRMLRDLV 538
Query 294 GASGFRKGMDMYFERHDNTAATCDDFRAAM---AD--ANRINLDQ-MDRWYSQAGTPRLE 347
F+ + Y ++ + + DD A++ AD A + L ++ W+ G P +
Sbjct 539 SDFDFKAAVRRYLRKNAYRSVSRDDLFASLPAYADHGAEQEKLSHVLEGWFVNEGIPEIT 598
Query 348 VLRS 351
++R+
Sbjct 599 LIRN 602
> mmu:80898 Erap1, Arts1, ERAAP, PILSA, PILSAP; endoplasmic reticulum
aminopeptidase 1; K09604 adipocyte-derived leucine aminopeptidase
[EC:3.4.11.-]
Length=930
Score = 96.3 bits (238), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 75/318 (23%), Positives = 145/318 (45%), Gaps = 23/318 (7%)
Query 14 TQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVL---LSNGNKTEEGLVHGSPDRH 70
TQ E R D P + A + ++++ + + L EGL+ + H
Sbjct 169 TQFEPTAARMAFPCFDEPALKASFSIKIKRDPRHLAISNMPLVKSVNVAEGLI----EDH 224
Query 71 FAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMHSVKV 130
F + +YL A + +F ++ TKSG V ++VY+ P ++++ ++A+ +
Sbjct 225 FDITVK---MSTYLVAFIISDFKSVSK--MTKSG--VKVSVYAVPDKINQADYALDAAVT 277
Query 131 SMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFERVL 190
+++ E++F Y L ++A + DF +GAMEN GL + + LL D + S+ +
Sbjct 278 LLEFYEDYFNIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESSLLYDKEKSSASSKLGIT 337
Query 191 AVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKE-----VAD 245
+V HE H W GN VT+ W L L EG F E F+ ++ ++++ +
Sbjct 338 MIVSHELAHQWFGNLVTMEWWNDLWLNEGFAKFME--FVSVTVTHPELKVEDYFFGKCFN 395
Query 246 LISRQFAEDDGPMAHPIRPESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKGMDMY 305
+ P++ P+ E+ + + Y+KGA ++ + L A F++G+ Y
Sbjct 396 AMEVDALNSSHPVSTPV--ENPAQIREMFDDVSYEKGACILNMLRDYLSADTFKRGIVQY 453
Query 306 FERHDNTAATCDDFRAAM 323
+++ +D +M
Sbjct 454 LQKYSYKNTKNEDLWNSM 471
> dre:100144556 zgc:172163; K13723 endoplasmic reticulum aminopeptidase
2 [EC:3.4.11.-]
Length=931
Score = 95.5 bits (236), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 96/369 (26%), Positives = 154/369 (41%), Gaps = 43/369 (11%)
Query 14 TQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNG--NKTEEGLVHGSPDRHF 71
T E R D P A Y VR+ + + LSN +T E + +G + HF
Sbjct 171 THFEPTSARMALPCFDEPVFKANYTVRIRRGPSH--IALSNMPLEQTVE-ISNGLFEDHF 227
Query 72 AVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMHSVKVS 131
SYL A + +F ++ T +G + +++Y+ P + H+ +A+ +
Sbjct 228 EASVK---MSSYLLAFIVCDFKSVSG--LTATG--INISIYAVPEKWHQTHYALEAALRL 280
Query 132 MKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFERVLA 191
+++ E++F Y L ++ + DF +GAMEN GL + T LL D S+ D V
Sbjct 281 LEFYEQYFNILYPLPKLDLIAIPDFESGAMENWGLTTYRETSLLYDPDISSASDKLWVTM 340
Query 192 VVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEVADLISRQF 251
V+GHE H W GN VT+ W + L EG + E + + V ++ D
Sbjct 341 VIGHELAHQWFGNLVTMDWWNDIWLNEGFARYMESVSVEAVYPE-LKVEDHFLDTCFGAI 399
Query 252 AEDDGPMAHPIRP--ESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKGMDMYFERH 309
D + PI E+ + + Y+KGA ++ + L GF+ G+ Y R
Sbjct 400 GRDSLNSSRPISSLAENPTQIKEMFDTVSYEKGACILHMLRHFLTDEGFQSGIIRYLRRF 459
Query 310 -----------DNTAATC--DDFRA-------AMADAN-------RINLDQ-MDRWYSQA 341
D+ TC +DF A A A N ++L + M+ W Q
Sbjct 460 SYCNARNEDLWDSLIKTCSEEDFAAGEYCYSSAQATKNAYRFAGEHVDLKKMMNTWTLQK 519
Query 342 GTPRLEVLR 350
G P + V R
Sbjct 520 GIPLVTVKR 528
> hsa:64167 ERAP2, FLJ23633, FLJ23701, FLJ23807, L-RAP, LRAP;
endoplasmic reticulum aminopeptidase 2 (EC:3.4.11.-); K13723
endoplasmic reticulum aminopeptidase 2 [EC:3.4.11.-]
Length=960
Score = 95.1 bits (235), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 64/248 (25%), Positives = 120/248 (48%), Gaps = 9/248 (3%)
Query 82 SYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMHSVKVSMKWEEEHFGR 141
+YL A + +F ++ T SG V +++Y+ P + ++ +A+ + + + E++F
Sbjct 261 TYLVAYIVCDFHSLSG--FTSSG--VKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDI 316
Query 142 EYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFERVLAVVGHEYFHNW 201
Y L ++ + DF GAMEN GL + T LL D +TS+ D V V+ HE H W
Sbjct 317 YYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQW 376
Query 202 TGNRVTVRDWFQLTLKEGLTVFREQLFMGTV---MSAGVQRIKEVADLISRQFAEDDGPM 258
GN VT+ W + LKEG + E + + + + ++I++ P+
Sbjct 377 FGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPI 436
Query 259 AHPIRPESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKGMDMYFERHDNTAATCDD 318
+ P E+ + + Y+KGA ++ + LG F+KG+ Y ++ A DD
Sbjct 437 SKP--AETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDD 494
Query 319 FRAAMADA 326
++++++
Sbjct 495 LWSSLSNS 502
> dre:564068 endoplasmic reticulum aminopeptidase 1-like; K09604
adipocyte-derived leucine aminopeptidase [EC:3.4.11.-]
Length=908
Score = 94.7 bits (234), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 80/316 (25%), Positives = 140/316 (44%), Gaps = 20/316 (6%)
Query 3 KGLYVSGSALV-----TQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNK 57
KG Y + S V TQ E R D P A + +R+ + + +SN K
Sbjct 128 KGQYTTNSGEVRMLASTQFEPTHARAAFPCFDEPAFKANFTIRVR--RESRHISISNMPK 185
Query 58 TEE-GLVHGSPDRHFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPA 116
L G + F +YL A + +F +I + KS + V ++VY+ P
Sbjct 186 LRTVELADGILEDQFDTMVK---MSTYLVAFIICDFHSI----SKKSQHGVEISVYTVPE 238
Query 117 QLHKLEWAMHSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLA 176
++ + E+A+ + + + +E+F Y L ++A + DF +GAMEN GL+ + + LL
Sbjct 239 KISQAEYALDTAVTMLDFYDEYFDIPYPLPKHDLAAIPDFQSGAMENWGLSTYRESGLLF 298
Query 177 DMQTSTDDDFERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTV---M 233
D + S+ D + V+ HE H W GN VT++ W L L EG F E + + +
Sbjct 299 DPEKSSSSDKLGITKVIAHELAHQWFGNLVTMQWWNDLWLNEGFAKFMEYVSVNITHPEL 358
Query 234 SAGVQRIKEVADLISRQFAEDDGPMAHPIRPESYMAMDNFYTATVYDKGAEVVRIYHTLL 293
+++ +S P++ P+ E+ + + Y KGA ++ + L
Sbjct 359 QVNDYFLEKCFTALSVDSLSSSHPVSTPV--ENPAEISEMFDDVSYRKGACILNMLRDFL 416
Query 294 GASGFRKGMDMYFERH 309
F+ G+ Y ++H
Sbjct 417 TPEVFKYGIINYLKKH 432
> cel:R03G8.4 hypothetical protein
Length=786
Score = 91.3 bits (225), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 88/346 (25%), Positives = 148/346 (42%), Gaps = 25/346 (7%)
Query 13 VTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEGLVHGSPDRHFA 72
VTQ E R + D P+ A + V + LSN + + + D
Sbjct 160 VTQFEPTAARFMVPCFDEPEFKAIWHVTVVHPTGS--TALSNAKEIDN--TKTNDDFSTT 215
Query 73 VFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMHSVKVSM 132
F SY+ AI G+ + TK+G V + VYS+P + ++ A++ ++ +
Sbjct 216 EFESTLKMSSYILAIFVGDVQF--KEAVTKNG--VRIRVYSDPGHIDSVDHALNVSRIVL 271
Query 133 KWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFERVLAV 192
+ E+ FG Y++D ++ V +F GAMEN GL + L+ ++ D + V
Sbjct 272 EGFEKQFGYPYEMDKLDLIAVYNFRYGAMENWGLIVHQAYTLIENLMPGNTD---IISEV 328
Query 193 VGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQR-IKEVADLISRQF 251
V HE H W GN VT++ W QL L EG + + T + R ++ Q
Sbjct 329 VAHEIAHQWFGNLVTMKFWDQLWLNEGFATYMTA-YGYTFLDPNYDRDYYYLSPQFESQS 387
Query 252 AEDDGPMAHPIRPESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKGMDMYFERHDN 311
+ GP+ I+ S+ A+ N + Y KG +R+ ++G F + + Y HD
Sbjct 388 GNELGPLNSMIKL-SHGAIGN--PSQNYAKGCSFIRMLEKIVGTEHFNEAIRTYLHTHDF 444
Query 312 TAATCDDFRAAM---ADANRIN-----LDQMDR-WYSQAGTPRLEV 348
+ + A+ +D IN +++ R W Q G P + V
Sbjct 445 SNVEDKNLYDALRVYSDKLEINGKPFDIEEFGRCWTHQTGYPTVYV 490
> dre:100004744 aminopeptidase N-like
Length=936
Score = 91.3 bits (225), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 86/343 (25%), Positives = 151/343 (44%), Gaps = 35/343 (10%)
Query 28 LDRPDVLAKYKVRLEANKAKYPVLLSNGNKTE--EGLVHGSPDRHFAVFTDPHPKPSYLF 85
D P + A + + L ++ V LSNG + E + +V G P F SYL
Sbjct 196 FDEPAMKAVFHITLIHDRGT--VALSNGMEIENVDTIVDGQP-VTVTTFEPTKIMSSYLL 252
Query 86 AILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKL--EWAMHSVKVSMKWEEEHFGREY 143
A++ ++ + T + + + +++ + ++A++ +K+ E ++ Y
Sbjct 253 ALVVSDYTNV-----TSADGTLQIRIWARKKAIEDGHGDYALNITGPILKFFENYYNVPY 307
Query 144 DLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFERVLAVVGHEYFHNWTG 203
L + + DF GAMEN GL ++ + LL D S++ + ER ++ HE H W G
Sbjct 308 PLSKSDQIALPDFYFGAMENWGLVMYRESNLLYDPTVSSNANKERTATIIAHELAHMWFG 367
Query 204 NRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEVADL--ISRQFAEDDGPMAHP 261
N VT++ W ++ L EG + ++G + +K++ L + R FA D +HP
Sbjct 368 NLVTLKWWNEVWLNEGFASYVS--YLGADFAEPSWNVKDLIILKDVHRVFAVDALASSHP 425
Query 262 --------IRPESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKGMDMYFERHDNTA 313
I+PE ++ F T + Y KGA V+R+ L F +G++ Y +
Sbjct 426 LSSKEEDIIKPEQ--IIEQFDTVS-YSKGASVLRMLSDFLTEPVFVQGLNTYLTMFADQN 482
Query 314 ATCDDFRAAMADA-NRINLDQ-------MDRWYSQAGTPRLEV 348
+D + A N+ MDRW Q G P + V
Sbjct 483 TVGEDLWDHLQTAVNKTGTVLPLSVKVIMDRWVLQMGFPVVTV 525
> cel:R03G8.6 hypothetical protein
Length=747
Score = 90.1 bits (222), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 89/346 (25%), Positives = 147/346 (42%), Gaps = 34/346 (9%)
Query 14 TQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEGLVHGSPDRHFAV 73
TQ E R + D P+ A + V LE LSNG + E + + D
Sbjct 164 TQFETIFARNMIPCFDEPEFKATWNVSLEHPTGS--TALSNGIEVESKV---NDDWKTTT 218
Query 74 FTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMHSVKVSMK 133
+ SY+ A+ G+ I+ K T + N V + VY++P + +++ A++ ++ ++
Sbjct 219 YKKTLKMSSYILALFIGD---IQFKETILN-NGVRIRVYTDPVNIDRVDHALNISRIVLE 274
Query 134 WEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFERVLAVV 193
E FG Y ++ + V +F GAMEN GL I N L+ D T+ +V
Sbjct 275 GFERQFGIRYPMEKLDFVSVQNFKFGAMENWGLVIHNAYSLIGDPMDVTE--------IV 326
Query 194 GHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEVADLISRQFAE 253
HE H W GN VT++ W + L EG + + T + QR ++ QF
Sbjct 327 IHEIAHQWFGNLVTMKYWDHIWLNEGFASYMTSYGL-TFLDPDYQR---DTFYLNCQFNP 382
Query 254 --DDGPMAHPIRPESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKGMDMYFERHDN 311
+DG ++ M+N ATVY KG VR+ + G F + + Y E++
Sbjct 383 QINDGGVSLNFGKNLSSVMNN--AATVYMKGCSFVRMLENIFGTEYFNEAIKFYLEKNQY 440
Query 312 TAATCDDFRAAM--------ADANRINLDQMDR-WYSQAGTPRLEV 348
+D A + ++++ R W Q G P ++V
Sbjct 441 DNVDDNDLYEAFRTSSETLDTNGKPFDIEKFARCWTHQNGFPTIQV 486
> dre:558452 fd60b03, wu:fd60b03; si:ch211-200o3.4 (EC:3.4.11.2)
Length=946
Score = 89.7 bits (221), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 67/241 (27%), Positives = 106/241 (43%), Gaps = 22/241 (9%)
Query 122 EWAMHSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTS 181
++A+ + + + E FG Y + + + DF AMEN G + + LL D +T+
Sbjct 309 DYALETTETILSHYENIFGLRYPMSKIDQIALPDFGVRAMENWGFISYQESGLLYDKETA 368
Query 182 TDDDFERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMS-AGVQRI 240
+ D E+V ++ HE H W GN VT+ W L LKEG T MS GV+ +
Sbjct 369 STFDEEQVTTLIAHELAHQWFGNLVTMSWWNDLWLKEGF---------ATYMSYKGVEAV 419
Query 241 K-EVADL-----ISRQFAEDDGPMAHPIRPESY-----MAMDNFYTATVYDKGAEVVRIY 289
++ DL I F D +HP+ +Y + + Y KGA V+R+
Sbjct 420 GWDLKDLIVLREIQTAFQMDSLNTSHPLSMNAYDVQTSSQISELFDDITYSKGAAVLRML 479
Query 290 HTLLGASGFRKGMDMYFERHDNTAATCDDFRAAMADANRINLDQ-MDRWYSQAGTPRLEV 348
T +G + F KG+ MY + D + I +D+ M W + G P L +
Sbjct 480 ATRMGENEFMKGVKMYLSKFQFENTVPKDLWECLNMDTHIKVDEFMKTWTEEVGYPVLTI 539
Query 349 L 349
+
Sbjct 540 I 540
> dre:100006808 trh-de, PAP-II; thyrotropin-releasing hormone-degrading
ectoenzyme
Length=994
Score = 87.4 bits (215), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 72/270 (26%), Positives = 127/270 (47%), Gaps = 18/270 (6%)
Query 99 FTTKSG---NEVALAVYSEP--AQLHKLEWAMHSVKVSMKWEEEHFGREYDLDIFNVACV 153
FT K N V + +Y+ P Q ++A+ K +++ +++F +Y L ++ V
Sbjct 309 FTYKEAVADNGVLIRLYARPDAIQSGSGDYALRITKRLLQFYQDYFKVKYSLPKLDLLAV 368
Query 154 SDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFERVLAVVGHEYFHNWTGNRVTVRDWFQ 213
AMEN GL++F +L D + S+ + VV HE H W G+ VT W
Sbjct 369 PKHPYSAMENWGLSVFVEQKILLDPEVSSFSYQMELTVVVVHEICHQWFGDLVTPVWWED 428
Query 214 LTLKEGLTVFREQL---FMGTVMSAGVQRIKEVADLISRQFAEDDGPMAHPIRPESYMA- 269
+ LKEG + E + F+ + QR + D++ D +HPI + + A
Sbjct 429 VWLKEGFAHYFEYIGADFLFPKWNMEKQRF--LTDVLHEVMLLDGLASSHPISQQVFEAT 486
Query 270 -MDNFYTATVYDKGAEVVRIYHTLLGASGFRKGMDMYFERHDNTAATCDDFRAAMADANR 328
+D + Y KGA ++R+ ++G + F++ ++ Y H A DD +++A +
Sbjct 487 DIDRVFDWIAYKKGAALIRMLANVMGQTLFQRALNDYLMTHMYGNAARDDLWNKLSEAMQ 546
Query 329 -----INLDQ-MDRWYSQAGTPRLEVLRSE 352
IN+ Q MDRW Q G P + + +++
Sbjct 547 REGKDINITQVMDRWTLQMGYPVVTISKND 576
> dre:562409 thyrotropin-releasing hormone-degrading ectoenzyme-like;
K01306 pyroglutamyl-peptidase II [EC:3.4.19.6]
Length=994
Score = 86.7 bits (213), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 71/270 (26%), Positives = 128/270 (47%), Gaps = 18/270 (6%)
Query 99 FTTKSG---NEVALAVYSEP--AQLHKLEWAMHSVKVSMKWEEEHFGREYDLDIFNVACV 153
FT K N V + +Y+ P Q ++A+ K +++ +++F +Y L ++ V
Sbjct 309 FTYKEAVADNGVLIRLYARPDAIQSGSGDYALRITKRLLQFYQDYFKVKYSLPKLDLLAV 368
Query 154 SDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFERVLAVVGHEYFHNWTGNRVTVRDWFQ 213
AMEN GL++F +L D S+ + VV HE H W G+ VT W
Sbjct 369 PKHPYAAMENWGLSVFVEQKILLDPDVSSFSYQMELTMVVVHEICHQWFGDLVTPVWWED 428
Query 214 LTLKEGLTVFREQLFMGT---VMSAGVQRIKEVADLISRQFAEDDGPMAHPIRPESYMA- 269
+ LKEG + E ++GT +++ + + D++ D +HPI + + A
Sbjct 429 VWLKEGFAHYFE--YIGTDFLFPKWNMEKQRFLTDVLHEVMLLDGLASSHPISQQVFEAT 486
Query 270 -MDNFYTATVYDKGAEVVRIYHTLLGASGFRKGMDMYFERHDNTAATCDDFRAAMADANR 328
+D + Y KGA ++R+ ++G + F++ ++ Y H A DD +++A +
Sbjct 487 DIDRVFDWIAYKKGAALIRMLANVMGQTLFQRALNDYLMTHMYGNAARDDLWNKLSEAMQ 546
Query 329 -----INLDQ-MDRWYSQAGTPRLEVLRSE 352
IN+ Q MDRW Q G P + + +++
Sbjct 547 REGKDINITQVMDRWTLQMGYPVVTISKND 576
> cel:T16G12.1 hypothetical protein
Length=1890
Score = 84.3 bits (207), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 83/327 (25%), Positives = 142/327 (43%), Gaps = 26/327 (7%)
Query 12 LVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEGLVHGSPDRHF 71
+ T E R++ LD P AK+ + ++ ++ V LSN +TE + D +
Sbjct 215 IATHMEPFSARKVFPSLDEPSYKAKFTITVQYPASQ--VALSNMMETEPTKI----DNIW 268
Query 72 AVFTDPH-PK-PSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMHSVK 129
+ T P PK SYL A G + + ++ K N + A + P L++A +
Sbjct 269 STITFPQTPKMSSYLIAFAVGPY--VNSQYVNKH-NTLTRA-WGWPGTEQYLQFAAQNAG 324
Query 130 VSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFERV 189
+ E+ G ++ L + + +F AGAMEN GL I+ + + T T + E
Sbjct 325 ECLYQLGEYTGIKFPLSKADQLGMPEFLAGAMENWGLIIYKYQYIAYNPTTMTTRNMEAA 384
Query 190 LAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSA------GVQRIKEV 243
V+ HE H W G+ VT W L L EG + +V +Q + E+
Sbjct 385 AKVMCHELAHQWFGDLVTTAWWDDLFLNEGFADYFMTFIQKSVYPQQATYLDTLQVLDEL 444
Query 244 ADLISRQFAEDDGPMAHPIRPESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKGMD 303
++ D P+ +P P A D+ Y+KGA ++R+ +LGA F++G+
Sbjct 445 QVGLTADVRYDAHPLVYPDGP----AFDDI----TYNKGASMLRMLSDVLGADVFKQGIR 496
Query 304 MYFERHDNTAATCDDFRAAMADANRIN 330
Y ++ + A D + + D + N
Sbjct 497 AYLQKMQYSNANDFDLFSTLTDTAKSN 523
Score = 60.5 bits (145), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 41/141 (29%), Positives = 68/141 (48%), Gaps = 6/141 (4%)
Query 82 SYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMHSVKVSMKWEEEHFGR 141
+YL A+ G F+ + T++G V V++ E+A++ ++ + E +F
Sbjct 1205 TYLLALCVGHFSNLAT--VTRTG--VLTRVWTWSGMEQYGEFALNVTAGTIDFMENYFSY 1260
Query 142 EYDLDIFNVACVSDF--NAGAMENKGLNIFNCTLLLADMQTSTDDDFERVLAVVGHEYFH 199
++ L +V + ++ NAGAMEN GL I +L + D +T D V HE H
Sbjct 1261 DFPLKKLDVMALPEYTMNAGAMENWGLIIGEYSLFMFDPDYATTRDITEVAETTAHEVVH 1320
Query 200 NWTGNRVTVRDWFQLTLKEGL 220
W G+ VT+ W + L EG
Sbjct 1321 QWFGDIVTLDWWNDIFLNEGF 1341
> cel:F49B2.6 hypothetical protein
Length=1082
Score = 80.5 bits (197), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 85/382 (22%), Positives = 165/382 (43%), Gaps = 51/382 (13%)
Query 2 LKGLYVSG---------SALVTQCEAEGFRRITYFLDRPDVLAKYKVRLEAN-----KAK 47
L+GLY S + TQ E R++ D P+ A ++V + N ++
Sbjct 301 LQGLYFSTHLGTDGKKTKSAATQFEPTFARKMLPCFDEPNFKATFQVAIIRNPHHIARSN 360
Query 48 YPVLLSNGNKTEEGLVHGSPDRHFAVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEV 107
+L+S K GL+ VF +YL A+ + + T + +
Sbjct 361 MNILISKEYKN--GLIKD-------VFEKSVKMSTYLLAVAVLDGYGYIKRLTRNTQKAI 411
Query 108 ALAVYSEPAQLH-KLEWAMHSVKVSMKWEEEHFGREYDLDIFNVACVSDFNAGAMENKGL 166
+ +Y+ L + E+ + + ++++ E++F Y LD ++ + DF+ GAMEN GL
Sbjct 412 EVRLYAPQDMLTGQSEFGLDTTIRALEFFEDYFNISYPLDKIDLLALDDFSEGAMENWGL 471
Query 167 NIFNCTLLLADMQTSTDDDFERVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQ 226
F + LL + + ++ E + ++ HE H W GN VT+ W ++ L EG + E
Sbjct 472 VTFRDSALLFNERKASVVAKEHIALIICHEIAHQWFGNLVTMDWWNEVFLNEGFANYMEY 531
Query 227 LFMGTVMSAGVQRIKEVADLISRQFAEDDGPMAHPIRPESYM-----------AMDNFYT 275
V+ + ++SR +AE+ +A P+ ++ ++ N +
Sbjct 532 --------KCVEHLFPDWSIMSRFYAEN---LAFSQEPDGFLSSRAIESDDDDSLLNLFD 580
Query 276 ATVYDKGAEVVRIYHTLLGASGFRKGMDMYFERHD-NTAATCDDFRAAMADAN---RINL 331
A Y K A ++ + + G F+ + Y ++ + A D ++ AN +++
Sbjct 581 AINYHKAAAIIHMIAEMAGQKNFQNALVEYLNKYAYSNAIGVDLWKIVEKHANLQGTVSI 640
Query 332 DQMDRWY-SQAGTPRLEVLRSE 352
+ + Y +Q G P L V R++
Sbjct 641 PDLAKAYTTQVGYPLLTVERTD 662
> hsa:4048 LTA4H; leukotriene A4 hydrolase (EC:3.3.2.6); K01254
leukotriene-A4 hydrolase [EC:3.3.2.6]
Length=611
Score = 80.5 bits (197), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 87/353 (24%), Positives = 137/353 (38%), Gaps = 34/353 (9%)
Query 12 LVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEGLVHGSPDRHF 71
L +QC+A R I D P V Y E + K V L + + E P R
Sbjct 132 LFSQCQAIHCRAILPCQDTPSVKLTYTA--EVSVPKELVALMSAIRDGETPDPEDPSRKI 189
Query 72 AVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMHSVKVS 131
F P P YL A++ G + + T V+SE Q+ K + +
Sbjct 190 YKFIQKVPIPCYLIALVVGALESRQIGPRT--------LVWSEKEQVEKSAYEFSETESM 241
Query 132 MKWEEEHFGR----EYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFE 187
+K E+ G +YDL + + F G MEN L TLL D S
Sbjct 242 LKIAEDLGGPYVWGQYDLLVLPPS----FPYGGMENPCLTFVTPTLLAGDKSLSN----- 292
Query 188 RVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEVADLI 247
V+ HE H+WTGN VT + W L EG TV+ E+ G + + +
Sbjct 293 ----VIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWG 348
Query 248 SRQFAEDDGPMAHP----IRPESYMAMDNFYTATVYDKGAEVVRIYHTLLGASGFRKG-M 302
Q + HP + + + D Y++ Y+KG ++ LLG G +
Sbjct 349 ELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFL 408
Query 303 DMYFERHDNTAATCDDFRAAMADANRINLDQMDR--WYSQAGTPRLEVLRSEY 353
Y E+ + T DD++ + + +D +++ W + +P L ++ Y
Sbjct 409 KAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNY 461
> cel:C42C1.11 hypothetical protein
Length=609
Score = 80.1 bits (196), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 87/360 (24%), Positives = 144/360 (40%), Gaps = 62/360 (17%)
Query 12 LVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEGLVHGSPDRHF 71
L +QC+A R I +D P V + Y+ + ++ + G + R
Sbjct 134 LFSQCQAINARSIVPCMDTPSVKSTYEAEVCVPIGLTCLMSAIGQGSTPSECG---KRTI 190
Query 72 AVFTDPHPKPSYLFAILAGEFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMHSVKVS 131
F P PSYL AI+ G R + + + AV++EP+Q + +
Sbjct 191 FSFKQPVSIPSYLLAIVVGHLE--RKEISERC------AVWAEPSQAEASFYEFAETEKI 242
Query 132 MKWEEEHFGR----EYDLDIFNVACVSDFNAGAMENKGLNIFNCTLLLADMQTSTDDDFE 187
+K E+ G YDL V + F G MEN L TLL D
Sbjct 243 LKVAEDVAGPYVWGRYDL----VVLPATFPFGGMENPCLTFITPTLLAGD---------R 289
Query 188 RVLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMSAGVQRIKEVADLI 247
++ V+ HE H+WTGN VT W L EG TVF E+ G + +
Sbjct 290 SLVNVIAHEISHSWTGNLVTNFSWEHFWLNEGFTVFLERKIHGKMYGE-----------L 338
Query 248 SRQFAEDDGPMAHPIR-------PE-SYMAM---------DNFYTATVYDKGAEVVRIYH 290
RQF + G +R P+ Y + D+ +++ Y+KG+ ++
Sbjct 339 ERQFESESGYEEALVRTVNDVFGPDHEYTKLVQNLGNADPDDAFSSVPYEKGSALLFTIE 398
Query 291 TLLG-ASGFRKGMDMYFERHDNTAATCDDFRAAMADA---NRINLDQMD--RWYSQAGTP 344
LG S F + + Y +++ + ++++ + D+ ++ LD +D W +AG P
Sbjct 399 QALGDNSRFEQFLRDYIQKYAYKTVSTEEWKEYLYDSFTDKKVILDNIDWNLWLHKAGLP 458
> cel:ZC416.6 hypothetical protein; K01254 leukotriene-A4 hydrolase
[EC:3.3.2.6]
Length=625
Score = 79.3 bits (194), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 62/226 (27%), Positives = 98/226 (43%), Gaps = 28/226 (12%)
Query 12 LVTQCEAEGFRRITYFLDRPDVLAKYKVRLEANKAKYPVLLSNGNKTEEGLVHGSPDRHF 71
L +QC+A R I +D P V + Y+ + ++ + G ++ G D
Sbjct 138 LFSQCQAIHARSIVPCMDTPSVKSTYEAEVTVPTGMTCLMSAIGQGSK-----GDDDTTT 192
Query 72 AVFTDPHPKPSYLFAILAG--EFAAIRDKFTTKSGNEVALAVYSEPAQLHKLEWAMHSVK 129
+ P PSYL AI+ G E I D+ AV++EP+ + K W +
Sbjct 193 FFYKQPVAIPSYLIAIVVGCLEKRDISDR----------CAVWAEPSVVDKAHWEFAETE 242
Query 130 VSMKWEEEHFGREYDLDIFNVACVS-DFNAGAMENKGLNIFNCTLLLADMQTSTDDDFER 188
+ EE G+ Y +++ C+ F G MEN L TL+ D
Sbjct 243 DILASAEEIAGK-YIWGRYDMVCLPPSFPFGGMENPCLTFLTPTLIAGD---------RS 292
Query 189 VLAVVGHEYFHNWTGNRVTVRDWFQLTLKEGLTVFREQLFMGTVMS 234
+++V+ HE H+W+GN VT W L EG T+F E+ G ++S
Sbjct 293 LVSVIAHEIAHSWSGNLVTNSSWEHFWLNEGFTMFIERKICGRLVS 338
Lambda K H
0.321 0.135 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 15576435624
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
Posted date: Sep 16, 2011 8:45 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40