bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
164,496 sequences; 82,071,388 total letters
Query= Eace_0493_orf1
Length=279
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_109730 thioredoxin reductase, putative (EC:1.8.1.7)... 253 6e-67
bbo:BBOV_I002190 19.m02214; thiodoxin reductase (EC:1.8.1.9); ... 252 1e-66
cpv:cgd2_4320 thioredoxin reductase 1 ; K00384 thioredoxin red... 250 4e-66
pfa:PFI1170c thioredoxin reductase (EC:1.8.1.9); K00384 thiore... 249 6e-66
tpv:TP03_0110 thioredoxin reductase (EC:1.6.4.5); K00384 thior... 245 1e-64
xla:447610 txnrd1, MGC85342; thioredoxin reductase 1 (EC:1.8.1... 207 5e-53
mmu:26462 Txnrd2, AA118373, ESTM573010, TGR, Tr3, Trxr2, Trxrd... 205 2e-52
hsa:7296 TXNRD1, GRIM-12, MGC9145, TR, TR1, TRXR1, TXNR; thior... 201 3e-51
mmu:50493 Txnrd1, TR, TR1, TrxR1; thioredoxin reductase 1 (EC:... 201 3e-51
hsa:10587 TXNRD2, SELZ, TR, TR-BETA, TR3, TRXR2; thioredoxin r... 199 1e-50
xla:379744 txnrd2, MGC69182; thioredoxin reductase 2 (EC:1.8.1... 197 4e-50
hsa:114112 TXNRD3, TGR, TR2, TRXR3; thioredoxin reductase 3 (E... 196 6e-50
dre:798259 im:7135991; si:ch1073-179p4.3 195 2e-49
dre:352924 txnrd1, TrxR1, cb682, fb83a08, wu:fb83a08; thioredo... 194 3e-49
mmu:232223 Txnrd3, AI196535, TR2, Tgr; thioredoxin reductase 3... 194 3e-49
cel:C06G3.7 trxr-1; ThioRedoXin Reductase family member (trxr-... 189 1e-47
xla:447484 txnrd3, MGC81848; thioredoxin reductase 3 (EC:1.8.1... 187 3e-47
cel:ZK637.10 trxr-2; ThioRedoXin Reductase family member (trxr... 155 1e-37
ath:AT3G54660 GR; GR (GLUTATHIONE REDUCTASE); ATP binding / gl... 115 3e-25
cel:C46F11.2 hypothetical protein 112 1e-24
ath:AT3G24170 ATGR1; ATGR1 (glutathione-disulfide reductase); ... 111 3e-24
tgo:TGME49_046920 glutathione reductase, putative (EC:1.8.1.7)... 105 3e-22
xla:734372 gsr, MGC84926; glutathione reductase (EC:1.8.1.7); ... 104 3e-22
eco:b3500 gor, ECK3485, gorA, JW3467; glutathione oxidoreducta... 103 6e-22
mmu:14782 Gsr, AI325518, D8Ertd238e, Gr-1, Gr1; glutathione re... 101 3e-21
hsa:2936 GSR, MGC78522; glutathione reductase (EC:1.8.1.7); K0... 100 6e-21
sce:YPL091W GLR1, LPG17; Cytosolic and mitochondrial glutathio... 96.3 1e-19
dre:553575 MGC110010; zgc:110010 (EC:1.8.1.7); K00383 glutathi... 94.7 4e-19
dre:100332932 glutathione reductase-like 94.0 6e-19
pfa:PF14_0192 glutathione reductase (EC:1.8.1.7); K00383 gluta... 80.1 9e-15
ath:AT3G16950 LPD1; LPD1 (LIPOAMIDE DEHYDROGENASE 1); dihydrol... 72.0 2e-12
cel:LLC1.3 hypothetical protein; K00382 dihydrolipoamide dehyd... 66.6 1e-10
ath:AT4G16155 dihydrolipoyl dehydrogenase; K00382 dihydrolipoa... 63.5 7e-10
ath:AT1G48030 mtLPD1; mtLPD1 (mitochondrial lipoamide dehydrog... 60.1 9e-09
tgo:TGME49_019130 glutathione reductase, putative (EC:1.8.1.7) 60.1 1e-08
ath:AT3G17240 mtLPD2; mtLPD2 (LIPOAMIDE DEHYDROGENASE 2); ATP ... 58.5 3e-08
eco:b0116 lpd, dhl, ECK0115, JW0112, lpdA; lipoamide dehydroge... 58.2 4e-08
bbo:BBOV_IV007190 23.m05858; dihydrolipoamide dehydrogenase (E... 56.6 1e-07
pfa:PF08_0066 lipoamide dehydrogenase, putative (EC:1.8.1.4); ... 55.1 3e-07
tgo:TGME49_006470 dihydrolipoyl dehydrogenase, putative (EC:1.... 53.9 7e-07
sce:YPL017C IRC15; Irc15p; K00382 dihydrolipoamide dehydrogena... 53.5 9e-07
pfa:PFL1550w lipoamide dehydrogenase (EC:1.8.1.4); K00382 dihy... 52.0 2e-06
eco:b3962 sthA, ECK3954, JW5551, sth, udhA; pyridine nucleotid... 51.6 3e-06
mmu:13382 Dld, AI315664, AI746344; dihydrolipoamide dehydrogen... 51.6 3e-06
tgo:TGME49_105980 dihydrolipoyl dehydrogenase protein, putativ... 50.4 8e-06
dre:399479 dldh, wu:fb24b05; dihydrolipoamide dehydrogenase (E... 49.3 1e-05
sce:YFL018C LPD1, HPD1; Dihydrolipoamide dehydrogenase, the li... 47.0 7e-05
> tgo:TGME49_109730 thioredoxin reductase, putative (EC:1.8.1.7);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=662
Score = 253 bits (646), Expect = 6e-67, Method: Compositional matrix adjust.
Identities = 130/243 (53%), Positives = 157/243 (64%), Gaps = 18/243 (7%)
Query 32 VSGAAGGSSAASASGAAGGGSSVSVCLFDYVRPSPRGSVWGLGGTCVNVGCIPKKLMHYA 91
+ G +GG + A + A G + V FD+V+PS +GS WGLGGTCVNVGC+PK L H+
Sbjct 165 IGGGSGGLACAKMAAAQGAETVV----FDFVQPSTQGSTWGLGGTCVNVGCVPKYLFHHT 220
Query 92 AQLQQQLAWDCRQLGCL-SFERFHPSTGEPLPHMQTCCWSQLVQCVQSYIKQLNFSYRVG 150
WD +G FE + W V+ VQ+YIK LNF YR G
Sbjct 221 GLAGANAHWDGPHMGWKGKFE-------------EQVDWGVCVEKVQNYIKSLNFGYRTG 267
Query 151 LRSAGCTYINAAARLVGPHTVEYEVKGEKKQLTARYILIAVGGRPYIPSGVRGAREFAIT 210
LR AG TYINA A+ V PH + Y +GE K AR I++AVGGRP+IP V GA+E AIT
Sbjct 268 LRKAGVTYINAYAKFVSPHELAYTFRGEDKICKARNIVVAVGGRPHIPEEVEGAKELAIT 327
Query 211 SDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVTVAYRSILLRGFDRQSAEKVGSC 270
SDDIFSLK P KTL VG SYI+LECAGFL +LG+ VTVA RSILLRGFDRQ AE+VG C
Sbjct 328 SDDIFSLKQAPNKTLCVGASYISLECAGFLRELGFDVTVAVRSILLRGFDRQCAEQVGLC 387
Query 271 MQE 273
++E
Sbjct 388 LEE 390
> bbo:BBOV_I002190 19.m02214; thiodoxin reductase (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=559
Score = 252 bits (644), Expect = 1e-66, Method: Compositional matrix adjust.
Identities = 135/273 (49%), Positives = 173/273 (63%), Gaps = 19/273 (6%)
Query 4 SQQGAAAAASSSSSSASNPGSAASAASGVSGAAGGSS--AASASGAAGGGSSVSVCLFDY 61
++ ++ S++++SA +P S ++ GG S AA+ A G +V LFDY
Sbjct 43 NENLSSLKMSNTNNSAIDPSSVEPELYDLAVIGGGCSGLAAAKEAARLGAKTV---LFDY 99
Query 62 VRPSPRGSVWGLGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFERFHPSTGEPL 121
VRPSPRG+ WGLGGTCVNVGCIPKKLMHYA L D LG H
Sbjct 100 VRPSPRGTKWGLGGTCVNVGCIPKKLMHYAGILGHA-EHDREMLGWSDASPKHD------ 152
Query 122 PHMQTCCWSQLVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEVKGEKKQ 181
WS+++Q +Q+Y+K LNFSYR GL + G YINA A L H V Y ++
Sbjct 153 -------WSKMIQTIQNYVKMLNFSYRSGLLTTGVKYINAFATLEKDHQVSYLGPNGPER 205
Query 182 LTARYILIAVGGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLS 241
+ A++ILIA+G RP IP V+GA E++ITSDD+ SL P GKTL+VGGS++ALECAGFL+
Sbjct 206 IKAKHILIAIGTRPIIPEEVKGAYEYSITSDDLMSLSHPVGKTLIVGGSFVALECAGFLT 265
Query 242 QLGYQVTVAYRSILLRGFDRQSAEKVGSCMQEL 274
LGY VTVA RSI+LRGFDRQ AEKVG M+ +
Sbjct 266 ALGYDVTVAVRSIILRGFDRQCAEKVGDLMENM 298
> cpv:cgd2_4320 thioredoxin reductase 1 ; K00384 thioredoxin reductase
(NADPH) [EC:1.8.1.9]
Length=526
Score = 250 bits (638), Expect = 4e-66, Method: Compositional matrix adjust.
Identities = 116/217 (53%), Positives = 150/217 (69%), Gaps = 14/217 (6%)
Query 56 VCLFDYVRPSPRGSVWGLGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFERFHP 115
V LFD+V+PS +G+ WGLGGTCVNVGC+PKKLMHY+A + + D + G + F
Sbjct 58 VALFDFVKPSTQGTKWGLGGTCVNVGCVPKKLMHYSALIASSIHHDAQMFGHKTSSSFE- 116
Query 116 STGEPLPHMQTCCWSQLVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEV 175
W +LV+ ++++I+ LNFSYR GLR YINA A+L+ PH+VEYE
Sbjct 117 -------------WGKLVETLRNHIRMLNFSYRTGLRVGNVEYINALAKLIDPHSVEYED 163
Query 176 KGEKKQLTARYILIAVGGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALE 235
G+KK +T+RYIL+A GGRP IP V GA +++ITSDDIF L PGKTLV+G SYI LE
Sbjct 164 NGQKKTITSRYILLATGGRPSIPETVPGAIQYSITSDDIFFLSKSPGKTLVIGASYIGLE 223
Query 236 CAGFLSQLGYQVTVAYRSILLRGFDRQSAEKVGSCMQ 272
AGFL++LG+ TVA RSI LRGFDRQ +EK+ M+
Sbjct 224 TAGFLNELGFDTTVAMRSIPLRGFDRQCSEKIVEYMK 260
> pfa:PFI1170c thioredoxin reductase (EC:1.8.1.9); K00384 thioredoxin
reductase (NADPH) [EC:1.8.1.9]
Length=617
Score = 249 bits (637), Expect = 6e-66, Method: Compositional matrix adjust.
Identities = 128/245 (52%), Positives = 162/245 (66%), Gaps = 20/245 (8%)
Query 32 VSGAAGGSSAASASGAAGGGSSVSVCLFDYVRPSPRGSVWGLGGTCVNVGCIPKKLMHYA 91
+ G GG ++A + A G V LFDYV+PS +G+ WG+GGTCVNVGC+PKKLMHYA
Sbjct 123 IGGGPGGMASAKEAAAHGA----RVLLFDYVKPSSQGTKWGIGGTCVNVGCVPKKLMHYA 178
Query 92 AQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQLVQCVQSYIKQLNFSYRVGL 151
+ D + G +F + L H W +LV VQS+I+ LNFSY GL
Sbjct 179 GHMGSIFKLDSKAYGW----KF-----DNLKH----DWKKLVTTVQSHIRSLNFSYMTGL 225
Query 152 RSAGCTYINAAARLVGPHTVEYEVKGE---KKQLTARYILIAVGGRPYIPSGVRGAREFA 208
RS+ YIN A+L +TV Y +KG+ ++ +T +YILIA G RP+IP V GA+E +
Sbjct 226 RSSKVKYINGLAKLKDKNTVSYYLKGDLSKEETVTGKYILIATGCRPHIPDDVEGAKELS 285
Query 209 ITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVTVAYRSILLRGFDRQSAEKVG 268
ITSDDIFSLK PGKTLVVG SY+ALEC+GFL+ LGY VTVA RSI+LRGFD+Q A KV
Sbjct 286 ITSDDIFSLKKDPGKTLVVGASYVALECSGFLNSLGYDVTVAVRSIVLRGFDQQCAVKVK 345
Query 269 SCMQE 273
M+E
Sbjct 346 LYMEE 350
> tpv:TP03_0110 thioredoxin reductase (EC:1.6.4.5); K00384 thioredoxin
reductase (NADPH) [EC:1.8.1.9]
Length=567
Score = 245 bits (626), Expect = 1e-64, Method: Compositional matrix adjust.
Identities = 120/215 (55%), Positives = 146/215 (67%), Gaps = 12/215 (5%)
Query 58 LFDYVRPSPRGSVWGLGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFERFHPST 117
LFDYV PSPRG+ WG+GGTCVNVGCIPKKLMHYA+ L+ +D Q G S
Sbjct 118 LFDYVTPSPRGTSWGVGGTCVNVGCIPKKLMHYASLLRST-QYDRFQYGITS-------- 168
Query 118 GEPLPHMQTCCWSQLVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEVKG 177
P + W++L Q +Q+Y+K LNFSYR GL +AG YINA L +TVEY
Sbjct 169 ---SPDQEQVNWTKLTQTIQNYVKMLNFSYRSGLTTAGVDYINAYGTLKHNNTVEYTHNN 225
Query 178 EKKQLTARYILIAVGGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECA 237
E K + ++IAVG RPY+PS V+GA E+AITSDD+F L T PGKTL+VG SY+ALECA
Sbjct 226 ETKSVVGEKVIIAVGERPYVPSDVQGALEYAITSDDLFKLNTSPGKTLIVGASYVALECA 285
Query 238 GFLSQLGYQVTVAYRSILLRGFDRQSAEKVGSCMQ 272
GFL+ LG+ V V+ RSILLRGFDRQ KV M+
Sbjct 286 GFLTGLGFDVDVSVRSILLRGFDRQCVRKVEELME 320
> xla:447610 txnrd1, MGC85342; thioredoxin reductase 1 (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=531
Score = 207 bits (526), Expect = 5e-53, Method: Compositional matrix adjust.
Identities = 120/260 (46%), Positives = 149/260 (57%), Gaps = 19/260 (7%)
Query 16 SSSASNPGSAASAASGVSGAAGGSSAASASGAAGGGSSVSVCLFDYVRPSPRGSVWGLGG 75
+ NP + G A++ AA G V V D+V PSP G+ WGLGG
Sbjct 35 ENKEDNPDQITYDYDLIVIGGGSGGLAASKEAAKYGKKVLV--LDFVTPSPLGTKWGLGG 92
Query 76 TCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQLVQC 135
TCVNVGCIPKKLMH AA L+Q L D ++ G + + H W +
Sbjct 93 TCVNVGCIPKKLMHQAALLRQALK-DSQKYGW--------QIADNIQH----NWETMTDS 139
Query 136 VQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVE-YEVKGEKKQLTARYILIAVGGR 194
VQ+YI LNF+YRV L Y N VGP+T++ +G+ K TA LIA G R
Sbjct 140 VQNYIGSLNFNYRVALMENNVKYENGYGEFVGPNTIKSTNSRGKSKYFTAEKFLIATGER 199
Query 195 P-YIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVTVAYRS 253
P Y+ G+ G +E+ ITSDD+FSL PGKTLVVG SY+ALECAGFL+ LG VTV RS
Sbjct 200 PRYL--GIPGDKEYCITSDDLFSLTYCPGKTLVVGASYVALECAGFLAGLGLDVTVMVRS 257
Query 254 ILLRGFDRQSAEKVGSCMQE 273
ILLRGFD+Q A K+G M+E
Sbjct 258 ILLRGFDQQMANKIGEYMEE 277
> mmu:26462 Txnrd2, AA118373, ESTM573010, TGR, Tr3, Trxr2, Trxrd2;
thioredoxin reductase 2 (EC:1.8.1.9); K00384 thioredoxin
reductase (NADPH) [EC:1.8.1.9]
Length=527
Score = 205 bits (521), Expect = 2e-52, Method: Compositional matrix adjust.
Identities = 124/257 (48%), Positives = 151/257 (58%), Gaps = 26/257 (10%)
Query 25 AASAASG--------VSGAAGGSSAASASGAAGGGSSVSVCLFDYVRPSPRGSVWGLGGT 76
AASAA G + G +GG A A AA G V+V DYV PSPRG+ WGLGGT
Sbjct 33 AASAAGGQQSFDLLVIGGGSGG--LACAKEAAQLGKKVAVA--DYVEPSPRGTKWGLGGT 88
Query 77 CVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQLVQCV 136
CVNVGCIPKKLMH AA L + D G +P+ H W + + V
Sbjct 89 CVNVGCIPKKLMHQAALLGGMIR-DAHHYGW--------EVAQPVQH----NWKTMAEAV 135
Query 137 QSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEVKGEKKQL-TARYILIAVGGRP 195
Q+++K LN+ +RV L+ Y N A V HTV KG K L +A +I+IA GGRP
Sbjct 136 QNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRP 195
Query 196 YIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVTVAYRSIL 255
P+ V+GA E+ ITSDDIF LK PGKTLVVG SY+ALECAGFL+ +G TV RSI
Sbjct 196 RYPTQVKGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTVMMRSIP 255
Query 256 LRGFDRQSAEKVGSCMQ 272
LRGFD+Q + V M+
Sbjct 256 LRGFDQQMSSLVTEHME 272
> hsa:7296 TXNRD1, GRIM-12, MGC9145, TR, TR1, TRXR1, TXNR; thioredoxin
reductase 1 (EC:1.8.1.9); K00384 thioredoxin reductase
(NADPH) [EC:1.8.1.9]
Length=649
Score = 201 bits (511), Expect = 3e-51, Method: Compositional matrix adjust.
Identities = 109/221 (49%), Positives = 140/221 (63%), Gaps = 17/221 (7%)
Query 55 SVCLFDYVRPSPRGSVWGLGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFERFH 114
V + D+V P+P G+ WGLGGTCVNVGCIPKKLMH AA L Q L D R G
Sbjct 187 KVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQ-DSRNYGW------- 238
Query 115 PSTGEPLPHMQTCCWSQLVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVE-Y 173
E + H W ++++ VQ++I LN+ YRV LR Y NA + +GPH ++
Sbjct 239 -KVEETVKHD----WDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKAT 293
Query 174 EVKGEKKQLTARYILIAVGGRP-YIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYI 232
KG++K +A LIA G RP Y+ G+ G +E+ I+SDD+FSL PGKTLVVG SY+
Sbjct 294 NNKGKEKIYSAERFLIATGERPRYL--GIPGDKEYCISSDDLFSLPYCPGKTLVVGASYV 351
Query 233 ALECAGFLSQLGYQVTVAYRSILLRGFDRQSAEKVGSCMQE 273
ALECAGFL+ +G VTV RSILLRGFD+ A K+G M+E
Sbjct 352 ALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEE 392
> mmu:50493 Txnrd1, TR, TR1, TrxR1; thioredoxin reductase 1 (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=499
Score = 201 bits (510), Expect = 3e-51, Method: Compositional matrix adjust.
Identities = 111/221 (50%), Positives = 138/221 (62%), Gaps = 17/221 (7%)
Query 55 SVCLFDYVRPSPRGSVWGLGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFERFH 114
V + D+V P+P G+ WGLGGTCVNVGCIPKKLMH AA L Q L D R G
Sbjct 37 KVLVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALK-DSRNYGW------- 88
Query 115 PSTGEPLPHMQTCCWSQLVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPH-TVEY 173
+ + H W ++ + VQS+I LN+ YRV LR Y NA R +GPH V
Sbjct 89 -KVEDTVKHD----WEKMTESVQSHIGSLNWGYRVALREKKVVYENAYGRFIGPHRIVAT 143
Query 174 EVKGEKKQLTARYILIAVGGRP-YIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYI 232
KG++K +A LIA G RP Y+ G+ G +E+ I+SDD+FSL PGKTLVVG SY+
Sbjct 144 NNKGKEKIYSAERFLIATGERPRYL--GIPGDKEYCISSDDLFSLPYCPGKTLVVGASYV 201
Query 233 ALECAGFLSQLGYQVTVAYRSILLRGFDRQSAEKVGSCMQE 273
ALECAGFL+ +G VTV RSILLRGFD+ A K+G M+E
Sbjct 202 ALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEE 242
> hsa:10587 TXNRD2, SELZ, TR, TR-BETA, TR3, TRXR2; thioredoxin
reductase 2 (EC:1.8.1.9); K00384 thioredoxin reductase (NADPH)
[EC:1.8.1.9]
Length=524
Score = 199 bits (505), Expect = 1e-50, Method: Compositional matrix adjust.
Identities = 114/231 (49%), Positives = 141/231 (61%), Gaps = 16/231 (6%)
Query 42 ASASGAAGGGSSVSVCLFDYVRPSPRGSVWGLGGTCVNVGCIPKKLMHYAAQLQQQLAWD 101
A A AA G V+V DYV PSP+G+ WGLGGTCVNVGCIPKKLMH AA L L D
Sbjct 53 ACAKEAAQLGRKVAVV--DYVEPSPQGTRWGLGGTCVNVGCIPKKLMHQAALLGG-LIQD 109
Query 102 CRQLGCLSFERFHPSTGEPLPHMQTCCWSQLVQCVQSYIKQLNFSYRVGLRSAGCTYINA 161
G +P+PH W ++ + VQ+++K LN+ +RV L+ Y N
Sbjct 110 APNYGW--------EVAQPVPH----DWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNI 157
Query 162 AARLVGPHTVEYEVKGEKK-QLTARYILIAVGGRPYIPSGVRGAREFAITSDDIFSLKTP 220
A V HTV KG K+ L+A +I+IA GGRP P+ + GA E+ ITSDDIF LK
Sbjct 158 KASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPTHIEGALEYGITSDDIFWLKES 217
Query 221 PGKTLVVGGSYIALECAGFLSQLGYQVTVAYRSILLRGFDRQSAEKVGSCM 271
PGKTLVVG SY+ALECAGFL+ +G T+ RSI LRGFD+Q + V M
Sbjct 218 PGKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPLRGFDQQMSSMVIEHM 268
> xla:379744 txnrd2, MGC69182; thioredoxin reductase 2 (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=504
Score = 197 bits (500), Expect = 4e-50, Method: Compositional matrix adjust.
Identities = 112/242 (46%), Positives = 142/242 (58%), Gaps = 18/242 (7%)
Query 32 VSGAAGGSSAASASGAAGGGSSVSVCLFDYVRPSPRGSVWGLGGTCVNVGCIPKKLMHYA 91
+ G +GG A A AA G V+V FDYV PSPRG+ WG+GGTCVNVGCIPKKLMH A
Sbjct 25 IGGGSGG--LACAKQAAQFGKKVAV--FDYVEPSPRGTKWGIGGTCVNVGCIPKKLMHQA 80
Query 92 AQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQLVQCVQSYIKQLNFSYRVGL 151
A + + + P G P+ W ++ VQ+Y+K LN+ +R+ L
Sbjct 81 ALIGSTM-------------KDAPHYGWGTPYEIQHDWGKMAGAVQNYVKSLNWGHRIQL 127
Query 152 RSAGCTYINAAARLVGPHTVEYEVKGEKKQL-TARYILIAVGGRPYIPSGVRGAREFAIT 210
+ Y N A V H + K K+ L TA+ I+IA GGRP P+ V GA E+ IT
Sbjct 128 QDKKVKYFNLKANFVDEHCIRGVTKAGKETLVTAQNIVIATGGRPKYPTHVPGALEYGIT 187
Query 211 SDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVTVAYRSILLRGFDRQSAEKVGSC 270
SDD+F LK PGKTLVVG SY++LECAGFL+ +G T RSI LRGFD+Q A V
Sbjct 188 SDDLFWLKESPGKTLVVGASYVSLECAGFLTGIGLNTTAMVRSIPLRGFDQQMAYLVADY 247
Query 271 MQ 272
M+
Sbjct 248 ME 249
> hsa:114112 TXNRD3, TGR, TR2, TRXR3; thioredoxin reductase 3
(EC:1.8.1.9); K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=607
Score = 196 bits (499), Expect = 6e-50, Method: Compositional matrix adjust.
Identities = 106/221 (47%), Positives = 140/221 (63%), Gaps = 17/221 (7%)
Query 55 SVCLFDYVRPSPRGSVWGLGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFERFH 114
V + D+V PSP+G+ WGLGGTCVNVGCIPKKLMH AA L Q L D R+ G ++
Sbjct 181 KVMVLDFVVPSPQGTSWGLGGTCVNVGCIPKKLMHQAALLGQALC-DSRKFGWEYNQQVR 239
Query 115 PSTGEPLPHMQTCCWSQLVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVE-Y 173
+ W + + +Q++I LN+ YR+ LR Y+N+ V H ++
Sbjct 240 HN------------WETMTKAIQNHISSLNWGYRLSLREKAVAYVNSYGEFVEHHKIKAT 287
Query 174 EVKGEKKQLTARYILIAVGGRP-YIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYI 232
KG++ TA +IA G RP Y+ G++G +E+ ITSDD+FSL PGKTLVVG SY+
Sbjct 288 NKKGQETYYTAAQFVIATGERPRYL--GIQGDKEYCITSDDLFSLPYCPGKTLVVGASYV 345
Query 233 ALECAGFLSQLGYQVTVAYRSILLRGFDRQSAEKVGSCMQE 273
ALECAGFL+ G VTV RSILLRGFD++ AEKVGS M++
Sbjct 346 ALECAGFLAGFGLDVTVMVRSILLRGFDQEMAEKVGSYMEQ 386
> dre:798259 im:7135991; si:ch1073-179p4.3
Length=371
Score = 195 bits (495), Expect = 2e-49, Method: Compositional matrix adjust.
Identities = 108/242 (44%), Positives = 145/242 (59%), Gaps = 18/242 (7%)
Query 32 VSGAAGGSSAASASGAAGGGSSVSVCLFDYVRPSPRGSVWGLGGTCVNVGCIPKKLMHYA 91
+ G +GG A + AA G V+V DYV PS +G+ WGLGGTCVNVGCIPKKLMH A
Sbjct 38 IGGGSGG--LACSKEAAQLGQKVAV--LDYVEPSLKGTKWGLGGTCVNVGCIPKKLMHQA 93
Query 92 AQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQLVQCVQSYIKQLNFSYRVGL 151
A L + D R+ G +P + W + + VQ++++ LN+ +RV L
Sbjct 94 ALLGTAVK-DARKYGW------------QIPETLSHDWPTMAEAVQNHVRSLNWGHRVQL 140
Query 152 RSAGCTYINAAARLVGPHTVE-YEVKGEKKQLTARYILIAVGGRPYIPSGVRGAREFAIT 210
+ Y+N L+ HTV +G++ +TAR IL+A GGRP P+ V GA EF IT
Sbjct 141 QDKKVKYLNMKGTLLDKHTVRAVNAQGKEMTVTARNILLATGGRPKYPTHVPGAMEFGIT 200
Query 211 SDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVTVAYRSILLRGFDRQSAEKVGSC 270
SDDIF LK P KTL++G SY++LECAGFL+ +G +V RSI LRGFD+Q + V
Sbjct 201 SDDIFWLKESPKKTLIIGASYVSLECAGFLTGIGLDTSVMVRSIALRGFDQQMSGLVTDY 260
Query 271 MQ 272
M+
Sbjct 261 ME 262
> dre:352924 txnrd1, TrxR1, cb682, fb83a08, wu:fb83a08; thioredoxin
reductase 1 (EC:1.8.1.9); K00384 thioredoxin reductase
(NADPH) [EC:1.8.1.9]
Length=602
Score = 194 bits (493), Expect = 3e-49, Method: Compositional matrix adjust.
Identities = 109/243 (44%), Positives = 142/243 (58%), Gaps = 21/243 (8%)
Query 32 VSGAAGGSSAASASGAAGGGSSVSVCLFDYVRPSPRGSVWGLGGTCVNVGCIPKKLMHYA 91
+ G +GG + + + G V + DYV P+P+G+ WGLGGTCVNVGCIPKKLMH
Sbjct 121 IGGGSGGLACSKEAATLGK----KVMVLDYVVPTPQGTAWGLGGTCVNVGCIPKKLMHQT 176
Query 92 AQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQLVQCVQSYIKQLNFSYRVGL 151
A L + D R+ G E+ T W + V +YI LN+ YRV L
Sbjct 177 ALLGTAME-DARKFGWEFAEQV------------THNWETMKTAVNNYIGSLNWGYRVSL 223
Query 152 RSAGCTYINAAARLVGPHTVEYEVK-GEKKQLTARYILIAVGGRP-YIPSGVRGAREFAI 209
R Y+NA A V PH ++ K G++ TA ++A G RP Y+ G+ G +EF I
Sbjct 224 RDKNVNYVNAYAEFVEPHKIKATNKRGKETFYTAAQFVLATGERPRYL--GIPGDKEFCI 281
Query 210 TSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVTVAYRSILLRGFDRQSAEKVGS 269
TSDD+FSL PGKTLVVG SY+ALEC GFL+ LG VT+ RSILLRGFD+ A++ G
Sbjct 282 TSDDLFSLPYCPGKTLVVGASYVALECGGFLAGLGLDVTIMVRSILLRGFDQDMADRAGE 341
Query 270 CMQ 272
M+
Sbjct 342 YME 344
> mmu:232223 Txnrd3, AI196535, TR2, Tgr; thioredoxin reductase
3 (EC:1.8.1.9); K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=652
Score = 194 bits (493), Expect = 3e-49, Method: Compositional matrix adjust.
Identities = 111/232 (47%), Positives = 144/232 (62%), Gaps = 19/232 (8%)
Query 44 ASGAAGGGSSVSVCLFDYVRPSPRGSVWGLGGTCVNVGCIPKKLMHYAAQLQQQLAWDCR 103
A AA G V V D+V PSP+G+ WGLGGTCVNVGCIPKKLMH AA L L D +
Sbjct 181 AKEAANLGKKVMV--LDFVVPSPQGTTWGLGGTCVNVGCIPKKLMHQAALLGHALQ-DAK 237
Query 104 QLGCLSFERFHPSTGEPLPHMQTCCWSQLVQCVQSYIKQLNFSYRVGLRSAGCTYINAAA 163
+ G + + H W + + +QS+I LN+ YRV LR G TY+N+
Sbjct 238 KYGW--------EYNQQVKHN----WEAMTEAIQSHIGSLNWGYRVTLREKGVTYVNSFG 285
Query 164 RLVGPHTVE-YEVKGEKKQLTARYILIAVGGRP-YIPSGVRGAREFAITSDDIFSLKTPP 221
V H ++ KG++ TA +IA G RP Y+ G++G +E+ ITSDD+FSL P
Sbjct 286 EFVDLHKIKATNKKGQETFYTASKFVIATGERPRYL--GIQGDKEYCITSDDLFSLPYCP 343
Query 222 GKTLVVGGSYIALECAGFLSQLGYQVTVAYRSILLRGFDRQSAEKVGSCMQE 273
G TLVVG SY+ LECAGFL+ LG VTV RS+LLRGFD++ AEKVGS +++
Sbjct 344 GCTLVVGASYVGLECAGFLAGLGLDVTVMVRSVLLRGFDQEMAEKVGSYLEQ 395
> cel:C06G3.7 trxr-1; ThioRedoXin Reductase family member (trxr-1);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=667
Score = 189 bits (479), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 102/219 (46%), Positives = 130/219 (59%), Gaps = 16/219 (7%)
Query 55 SVCLFDYVRPSPRGSVWGLGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFERFH 114
V D+V+PSP+G+ WGLGGTCVNVGCIPKKLMH A+ L + D ++ G
Sbjct 197 KVACLDFVKPSPQGTSWGLGGTCVNVGCIPKKLMHQASLLGHSIH-DAKKYGW------- 248
Query 115 PSTGEPLPHMQT-CCWSQLVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEY 173
LP + W+ L VQ +I LN+ YRV LR TYIN+ GP +
Sbjct 249 -----KLPEGKVEHQWNHLRDSVQDHIASLNWGYRVQLREKTVTYINSYGEFTGPFEISA 303
Query 174 EVKGEK-KQLTARYILIAVGGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYI 232
K +K ++LTA LI+ G RP P + G +E+ ITSDD+F L PGKTL VG SY+
Sbjct 304 TNKKKKVEKLTADRFLISTGLRPKYPE-IPGVKEYTITSDDLFQLPYSPGKTLCVGASYV 362
Query 233 ALECAGFLSQLGYQVTVAYRSILLRGFDRQSAEKVGSCM 271
+LECAGFL G+ VTV RSILLRGFD+ AE++ M
Sbjct 363 SLECAGFLHGFGFDVTVMVRSILLRGFDQDMAERIRKHM 401
> xla:447484 txnrd3, MGC81848; thioredoxin reductase 3 (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=596
Score = 187 bits (476), Expect = 3e-47, Method: Compositional matrix adjust.
Identities = 110/243 (45%), Positives = 143/243 (58%), Gaps = 20/243 (8%)
Query 32 VSGAAGGSSAASASGAAGGGSSVSVCLFDYVRPSPRGSVWGLGGTCVNVGCIPKKLMHYA 91
V G G A S A+ G V + D+V P+P+G+ WGLGGTCVNVGCIPKKLMH A
Sbjct 116 VIGGGSGGLACSKEAASFGKK---VMVLDFVVPTPQGTSWGLGGTCVNVGCIPKKLMHQA 172
Query 92 AQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQLVQCVQSYIKQLNFSYRVGL 151
A L Q L D R+ G +E E + H W + + +Q+YI LN+ YRV L
Sbjct 173 AILGQSLK-DSRKFG-WEYE-------EQVKHN----WETMREAIQNYIGSLNWGYRVAL 219
Query 152 RSAGCTYINAAARLVGPHTVE-YEVKGEKKQLTARYILIAVGGRP-YIPSGVRGAREFAI 209
R Y NA V H ++ KG++ TA ++A G RP Y+ + G +E+ I
Sbjct 220 RDKQVRYENAYGEFVESHKIKATNKKGKESFFTAEKFVVATGERPRYL--NIPGDKEYCI 277
Query 210 TSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVTVAYRSILLRGFDRQSAEKVGS 269
TSDD+FSL PGKTLVVG SY+ALECAGFL+ +G TV RSI LRGFD++ A + G+
Sbjct 278 TSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDATVMVRSIFLRGFDQEMANRAGA 337
Query 270 CMQ 272
M+
Sbjct 338 YME 340
> cel:ZK637.10 trxr-2; ThioRedoXin Reductase family member (trxr-2);
K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=503
Score = 155 bits (393), Expect = 1e-37, Method: Compositional matrix adjust.
Identities = 97/234 (41%), Positives = 126/234 (53%), Gaps = 19/234 (8%)
Query 32 VSGAAGGSSAASASGAAGGGSSVSVCLFDYVRPSPRGSVWGLGGTCVNVGCIPKKLMHYA 91
V GA G + S A G + V L D V P+P G WG+GGTC NVGCIPKKLMH A
Sbjct 25 VIGAGSGGLSCSKRAADLGAN---VALIDAVEPTPHGHSWGIGGTCANVGCIPKKLMHQA 81
Query 92 AQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQLVQCVQSYIKQLNFSYRVGL 151
A + ++L + G ++ E + H W+ L + V +K N+ YRV L
Sbjct 82 AIVGKELK-HADKYGWNGIDQ------EKIKHD----WNVLSKNVNDRVKANNWIYRVQL 130
Query 152 RSAGCTYINAAARLVGPHTVEY---EVKGEKKQLTARYILIAVGGRPYIPSGVRGAREFA 208
Y NA A V + + K L+A ++I+ G RP P+ + GA E
Sbjct 131 NQKKINYFNAYAEFVDKDKIVITGTDKNKTKNFLSAPNVVISTGLRPKYPN-IPGA-ELG 188
Query 209 ITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVTVAYRSILLRGFDRQ 262
ITSDD+F+L + PGKTL+VGG Y+ALECAGFLS V V RSI L+GFDR
Sbjct 189 ITSDDLFTLASVPGKTLIVGGGYVALECAGFLSAFNQNVEVLVRSIPLKGFDRD 242
> ath:AT3G54660 GR; GR (GLUTATHIONE REDUCTASE); ATP binding /
glutathione-disulfide reductase (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=565
Score = 115 bits (287), Expect = 3e-25, Method: Compositional matrix adjust.
Identities = 84/237 (35%), Positives = 119/237 (50%), Gaps = 21/237 (8%)
Query 36 AGGSSAASASGAAGGGSSVSVCLFDYVRPSPRGSVWGLGGTCVNVGCIPKKLMHYAAQLQ 95
AG ++ A G+S +VC + S + G+GGTCV GC+PKKL+ YA++
Sbjct 95 AGSGGVRASRFATSFGASAAVCELPFSTIS-SDTAGGVGGTCVLRGCVPKKLLVYASKYS 153
Query 96 QQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQLVQCVQSYIKQLNFSYRVGLRSAG 155
+ D G +E EP + W+ L+ + +++L Y+ L A
Sbjct 154 HEFE-DSHGFGW-KYET------EP-----SHDWTTLIANKNAELQRLTGIYKNILSKAN 200
Query 156 CTYINAAARLVGPHTVEYEVKGEKKQLTARYILIAVGGRPYIPSGVRGAREFAITSDDIF 215
I +++ PHTV+ + K T R ILIAVGGRP+IP + G +EFAI SD
Sbjct 201 VKLIEGRGKVIDPHTVDVD----GKIYTTRNILIAVGGRPFIPD-IPG-KEFAIDSDAAL 254
Query 216 SLKTPPGKTLVVGGSYIALECAGFLSQLGYQVTVAYR-SILLRGFDRQSAEKVGSCM 271
L + P K +VGG YIALE AG + L +V V R +LRGFD + VG M
Sbjct 255 DLPSKPKKIAIVGGGYIALEFAGIFNGLNCEVHVFIRQKKVLRGFDEDVRDFVGEQM 311
> cel:C46F11.2 hypothetical protein
Length=473
Score = 112 bits (281), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 75/203 (36%), Positives = 105/203 (51%), Gaps = 23/203 (11%)
Query 73 LGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGC-LSFERFHPSTGEPLPHMQTCCWSQ 131
LGGTCVNVGC+PKK+M Y L + D G ++ +F W
Sbjct 54 LGGTCVNVGCVPKKVM-YNCSLHAEFIRDHADYGFDVTLNKFD--------------WKV 98
Query 132 LVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEVKGEKKQLTARYILIAV 191
+ + YIK+LN Y GL+ + YI A TVE V G K + + LIAV
Sbjct 99 IKKSRDEYIKRLNGLYESGLKGSSVEYIRGRATFAEDGTVE--VNGAKYR--GKNTLIAV 154
Query 192 GGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVTVAY 251
GG+P IP+ ++GA E I SD F L+ P +T+VVG YIA+E AG L+ LG +
Sbjct 155 GGKPTIPN-IKGA-EHGIDSDGFFDLEDLPSRTVVVGAGYIAVEIAGVLANLGSDTHLLI 212
Query 252 R-SILLRGFDRQSAEKVGSCMQE 273
R +LR FD+ ++++ + M E
Sbjct 213 RYDKVLRTFDKMLSDELTADMDE 235
> ath:AT3G24170 ATGR1; ATGR1 (glutathione-disulfide reductase);
FAD binding / NADP or NADPH binding / glutathione-disulfide
reductase/ oxidoreductase (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=499
Score = 111 bits (278), Expect = 3e-24, Method: Compositional matrix adjust.
Identities = 83/247 (33%), Positives = 119/247 (48%), Gaps = 27/247 (10%)
Query 36 AGGSSAASASGAAGGGSSVSVCLFDYVRPSPRGSVWGLGGTCVNVGCIPKKLMHYAAQLQ 95
AG +A +A G+ V +C + P + G+GGTCV GC+PKK++ Y A
Sbjct 33 AGSGGVRAARFSANHGAKVGICELPF-HPISSEEIGGVGGTCVIRGCVPKKILVYGATYG 91
Query 96 QQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQLVQCVQSYIKQLNFSYRVGLRSAG 155
+L D + G E+ W +L+Q I +LN Y+ L +A
Sbjct 92 GELE-DAKNYGWEINEKVD------------FTWKKLLQKKTDEILRLNNIYKRLLANAA 138
Query 156 CTYINAAARLVGPHTVEY-EVKGEKKQLTARYILIAVGGR---PYIPSGVRGAREFAITS 211
R+VGP+ VE ++ G K TA++ILIA G R P IP E AITS
Sbjct 139 VKLYEGEGRVVGPNEVEVRQIDGTKISYTAKHILIATGSRAQKPNIP-----GHELAITS 193
Query 212 DDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVTVAYRSIL-LRGFDRQSAEKVGSC 270
D+ SL+ P + +V+GG YIA+E A +G V + +R L LRGFD + V
Sbjct 194 DEALSLEEFPKRAIVLGGGYIAVEFASIWRGMGATVDLFFRKELPLRGFDDEMRALVA-- 251
Query 271 MQELEGK 277
+ LEG+
Sbjct 252 -RNLEGR 257
> tgo:TGME49_046920 glutathione reductase, putative (EC:1.8.1.7);
K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=483
Score = 105 bits (261), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 70/212 (33%), Positives = 102/212 (48%), Gaps = 26/212 (12%)
Query 73 LGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQL 132
LGGTCVNVGC+PKK+M A + + L +L +F + T CW L
Sbjct 46 LGGTCVNVGCVPKKVMWCVASVHETL----HELKNFAF---------TVKEQPTFCWRTL 92
Query 133 VQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPH----------TVEYEVKGEKKQL 182
+YIK+LN Y L+++G T+ A AR P V G ++ +
Sbjct 93 KTNRDNYIKRLNNIYLNNLKNSGVTFFPAYARFAKPEAKTDGGLAHAIVLKSADGNEETV 152
Query 183 TARYILIAVGGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQ 242
TA ++LIA GGRP +G+ G E I SD F L+ P K ++G YIA+E AG +
Sbjct 153 TADHVLIASGGRP-AKAGIEG-EEHTINSDGFFELEEMPQKVALLGAGYIAVEFAGVFAA 210
Query 243 LGYQVTVAYR-SILLRGFDRQSAEKVGSCMQE 273
+ + + R LR FD + +V M++
Sbjct 211 MKCETHLFVRHERALRKFDDMISMRVDEFMRK 242
> xla:734372 gsr, MGC84926; glutathione reductase (EC:1.8.1.7);
K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=476
Score = 104 bits (260), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 73/207 (35%), Positives = 104/207 (50%), Gaps = 23/207 (11%)
Query 73 LGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQL 132
LGGTCVNVGC+PKK+M + A + + D H G +P ++ W +
Sbjct 52 LGGTCVNVGCVPKKIM-WNAAMHSEYIHD------------HADYGFEIPDVK-FTWKVI 97
Query 133 VQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEVKGEKKQLTARYILIAVG 192
+ +Y+ +LN Y+ L+ A I A EV G+K +A +ILIA G
Sbjct 98 KEKRDAYVSRLNDIYQNNLQKAQIEIIRGNANFTSDPEPTVEVNGQK--YSAPHILIATG 155
Query 193 GRPYIPSGVR--GAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVTVA 250
G+P +PS GA ITSD F L P +++VVG YIA+E AG LS LG + ++
Sbjct 156 GKPSMPSDAELPGA-SLGITSDGFFELTDLPRRSIVVGAGYIAVEIAGILSALGSKASLL 214
Query 251 YR-SILLRGFDRQSAEKVGSCMQELEG 276
R +LR FD + +C +ELE
Sbjct 215 IRQDKVLRTFDSIIS---SNCTEELEN 238
> eco:b3500 gor, ECK3485, gorA, JW3467; glutathione oxidoreductase
(EC:1.8.1.7); K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=450
Score = 103 bits (258), Expect = 6e-22, Method: Compositional matrix adjust.
Identities = 75/207 (36%), Positives = 103/207 (49%), Gaps = 21/207 (10%)
Query 73 LGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQL 132
LGGTCVNVGC+PKK+M +AAQ+++ + + P G + W L
Sbjct 38 LGGTCVNVGCVPKKVMWHAAQIRE------------AIHMYGPDYGFDTT-INKFNWETL 84
Query 133 VQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEVKGEKKQLTARYILIAVG 192
+ +YI +++ SY L I AR V T+ EV GE +TA +ILIA G
Sbjct 85 IASRTAYIDRIHTSYENVLGKNNVDVIKGFARFVDAKTL--EVNGE--TITADHILIATG 140
Query 193 GRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVTVAYR 252
GRP P + G E+ I SD F+L P + VVG YIA+E AG ++ LG + + R
Sbjct 141 GRPSHPD-IPGV-EYGIDSDGFFALPALPERVAVVGAGYIAVELAGVINGLGAKTHLFVR 198
Query 253 SIL-LRGFDRQSAEKVGSCMQELEGKQ 278
LR FD +E + M EG Q
Sbjct 199 KHAPLRSFDPMISETLVEVMNA-EGPQ 224
> mmu:14782 Gsr, AI325518, D8Ertd238e, Gr-1, Gr1; glutathione
reductase (EC:1.8.1.7); K00383 glutathione reductase (NADPH)
[EC:1.8.1.7]
Length=500
Score = 101 bits (252), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 73/208 (35%), Positives = 103/208 (49%), Gaps = 25/208 (12%)
Query 73 LGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFE-RFHPSTGEPLPHMQTCCWSQ 131
LGGTCVNVGC+PKK+M + + + D G S E +F W
Sbjct 76 LGGTCVNVGCVPKKVM-WNTAVHSEFMHDHVDYGFQSCEGKF--------------SWHV 120
Query 132 LVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEVKGEKKQLTARYILIAV 191
+ Q +Y+ +LN Y+ L + I+ A EV G K+ TA +ILIA
Sbjct 121 IKQKRDAYVSRLNTIYQNNLTKSHIEIIHGYATFADGPRPTVEVNG--KKFTAPHILIAT 178
Query 192 GGRPYIP--SGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVTV 249
GG P +P S + GA ITSD F L+ P ++++VG YIA+E AG LS LG + ++
Sbjct 179 GGVPTVPHESQIPGA-SLGITSDGFFQLEDLPSRSVIVGAGYIAVEIAGILSALGSKTSL 237
Query 250 AYR-SILLRGFDRQSAEKVGSCMQELEG 276
R +LR FD + +C +ELE
Sbjct 238 MIRHDKVLRNFDSLIS---SNCTEELEN 262
> hsa:2936 GSR, MGC78522; glutathione reductase (EC:1.8.1.7);
K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=522
Score = 100 bits (249), Expect = 6e-21, Method: Compositional matrix adjust.
Identities = 73/208 (35%), Positives = 103/208 (49%), Gaps = 25/208 (12%)
Query 73 LGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFE-RFHPSTGEPLPHMQTCCWSQ 131
LGGTCVNVGC+PKK+M + + + D G S E +F+ W
Sbjct 98 LGGTCVNVGCVPKKVM-WNTAVHSEFMHDHADYGFPSCEGKFN--------------WRV 142
Query 132 LVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEVKGEKKQLTARYILIAV 191
+ + +Y+ +LN Y+ L + I A EV G K+ TA +ILIA
Sbjct 143 IKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVSG--KKYTAPHILIAT 200
Query 192 GGRPYIP--SGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVTV 249
GG P P S + GA ITSD F L+ PG++++VG YIA+E AG LS LG + ++
Sbjct 201 GGMPSTPHESQIPGA-SLGITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSL 259
Query 250 AYR-SILLRGFDRQSAEKVGSCMQELEG 276
R +LR FD + +C +ELE
Sbjct 260 MIRHDKVLRSFDSMIST---NCTEELEN 284
> sce:YPL091W GLR1, LPG17; Cytosolic and mitochondrial glutathione
oxidoreductase, converts oxidized glutathione to reduced
glutathione; mitochondrial but not cytosolic form has a role
in resistance to hyperoxia (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=483
Score = 96.3 bits (238), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 63/191 (32%), Positives = 93/191 (48%), Gaps = 11/191 (5%)
Query 73 LGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQL 132
LGGTCVNVGC+PKK+M YA+ L +++ + G ++ P E L T W +
Sbjct 57 LGGTCVNVGCVPKKVMWYASDLATRVS-HANEYGL--YQNL-PLDKEHL----TFNWPEF 108
Query 133 VQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEVKGEKKQL-TARYILIAV 191
Q +Y+ +LN Y+ L + AR VE + + ++ +A +IL+A
Sbjct 109 KQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVAT 168
Query 192 GGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVTVAY 251
GG+ P + G E SD F L+ P K +VVG YI +E AG LG + +
Sbjct 169 GGKAIFPENIPGF-ELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVI 227
Query 252 R-SILLRGFDR 261
R +LR FD
Sbjct 228 RGETVLRKFDE 238
> dre:553575 MGC110010; zgc:110010 (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=425
Score = 94.7 bits (234), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 72/210 (34%), Positives = 101/210 (48%), Gaps = 27/210 (12%)
Query 73 LGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFE--RFHPSTGEPLPHMQTCCWS 130
LGGTCVNVGC+PKK+M + + D G FE + H S W
Sbjct 42 LGGTCVNVGCVPKKVM-WNTSTHAEYLHDHEDYG---FEGAKAHFS------------WQ 85
Query 131 QLVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEVKGEKKQLTARYILIA 190
+ +Y+ +LN YR L +I+ AR EV G K+ TA +ILI+
Sbjct 86 IIKHKRDAYVSRLNQIYRSNLEKGKIEFIHGYARFTDDPEPTVEVNG--KKYTATHILIS 143
Query 191 VGGRPYIPS--GVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVT 248
GG P S V G+ IT D F L++ P ++++VG YIA+E AG LS LG + +
Sbjct 144 TGGHPSTVSEDDVPGS-SLGITCDGFFELESCPKRSVIVGAGYIAVEMAGILSTLGSKTS 202
Query 249 VAYRS-ILLRGFDRQSAEKVGSCMQELEGK 277
+ R +LR FD A +C +EL+
Sbjct 203 IIIRQGGVLRNFD---ALISSNCTKELQNN 229
> dre:100332932 glutathione reductase-like
Length=461
Score = 94.0 bits (232), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 64/197 (32%), Positives = 91/197 (46%), Gaps = 30/197 (15%)
Query 71 WGLGGTCVNVGCIPKKLMHYAAQLQQQLA------WDCRQLGCLSFERFHPSTGEPLPHM 124
+ GGTCV GC+PKKL YA+Q + W +G SF+
Sbjct 37 YRYGGTCVIRGCVPKKLFVYASQFHEHFEDSAGFGW---TVGETSFD------------- 80
Query 125 QTCCWSQLVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEVKGEKKQLTA 184
W++L+ I +L YR GL +A ++ A LV HTV G+ ++A
Sbjct 81 ----WAKLIAAKDREIDRLEGLYRKGLENAKAKVFDSRAELVDAHTVRLTKTGQ--TVSA 134
Query 185 RYILIAVGGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLG 244
+I+IA GG P P E I+S++ F L+ P L+ GG YIA+E A LG
Sbjct 135 EHIVIATGGTPN-PHADLPGHELCISSNEAFHLEKLPKSILIAGGGYIAVEFANIFHGLG 193
Query 245 YQVTVAYR-SILLRGFD 260
+ T+ YR +L FD
Sbjct 194 VETTLIYRGKEILSRFD 210
> pfa:PF14_0192 glutathione reductase (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=500
Score = 80.1 bits (196), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 68/214 (31%), Positives = 96/214 (44%), Gaps = 33/214 (15%)
Query 73 LGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQL 132
LGGTCVNVGC+PKK+M AA + L + R G F LP L
Sbjct 36 LGGTCVNVGCVPKKIMFNAASVHDILE-NSRHYG------FDTKFSFNLP--------LL 80
Query 133 VQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEVKGEKKQ----------- 181
V+ YI++LN YR L A + + + +KG K
Sbjct 81 VERRDKYIQRLNNIYRQNLSKDKVDLYEGTASFLSENRI--LIKGTKDNNNKDNGPLNEE 138
Query 182 -LTARYILIAVGGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFL 240
L R ILIAVG +P P V+G E I+SD+ F++K K +VG YIA+E +
Sbjct 139 ILEGRNILIAVGNKPVFPP-VKGI-ENTISSDEFFNIK-ESKKIGIVGSGYIAVELINVI 195
Query 241 SQLGYQVTVAYR-SILLRGFDRQSAEKVGSCMQE 273
+LG + R + +LR FD + + M++
Sbjct 196 KRLGIDSYIFARGNRILRKFDESVINVLENDMKK 229
> ath:AT3G16950 LPD1; LPD1 (LIPOAMIDE DEHYDROGENASE 1); dihydrolipoyl
dehydrogenase; K00382 dihydrolipoamide dehydrogenase
[EC:1.8.1.4]
Length=623
Score = 72.0 bits (175), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 56/194 (28%), Positives = 88/194 (45%), Gaps = 25/194 (12%)
Query 73 LGGTCVNVGCIPKK-LMHYAAQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQ 131
+GGTCVN GC+P K L+ + ++++ L E S G +Q
Sbjct 120 VGGTCVNRGCVPSKALLAVSGRMRE-----------LQNEHHMKSFG-----LQVSAAGY 163
Query 132 LVQCVQSYIKQLNFSYRVGL----RSAGCTYINAAARLVGPHTVEYEVKGEKKQLTARYI 187
Q V + L R L ++ G + ++GP V+Y G+ +TA+ I
Sbjct 164 DRQGVADHANNLATKIRNNLTNSMKAIGVDILTGFGSVLGPQKVKY---GKDNIITAKDI 220
Query 188 LIAVGGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQV 247
+IA G P++P G+ + ITSD L++ P +VG YI LE + + LG +V
Sbjct 221 IIATGSVPFVPKGIEVDGKTVITSDHALKLESVPEWIAIVGSGYIGLEFSDVYTALGSEV 280
Query 248 T-VAYRSILLRGFD 260
T + L+ GFD
Sbjct 281 TFIEALDQLMPGFD 294
> cel:LLC1.3 hypothetical protein; K00382 dihydrolipoamide dehydrogenase
[EC:1.8.1.4]
Length=495
Score = 66.6 bits (161), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 58/181 (32%), Positives = 82/181 (45%), Gaps = 23/181 (12%)
Query 73 LGGTCVNVGCIPKKLM----HYAAQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCC 128
LGGTC+NVGCIP K + HY Q A R + C + LP M
Sbjct 64 LGGTCLNVGCIPSKALLNNSHYLHMAQHDFA--ARGIDC--------TASLNLPKMMEA- 112
Query 129 WSQLVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVE-YEVKGEKKQLTARYI 187
S V+ + IKQL + +VG ++ A +VGP+TV+ + G + + AR I
Sbjct 113 KSNSVKQLTGGIKQLFKANKVG-------HVEGFATIVGPNTVQAKKNDGSVETINARNI 165
Query 188 LIAVGGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQV 247
LIA G G+ + ++S SL P K +V+G I LE +LG +V
Sbjct 166 LIASGSEVTPFPGITIDEKQIVSSTGALSLGQVPKKMVVIGAGVIGLELGSVWQRLGAEV 225
Query 248 T 248
T
Sbjct 226 T 226
> ath:AT4G16155 dihydrolipoyl dehydrogenase; K00382 dihydrolipoamide
dehydrogenase [EC:1.8.1.4]
Length=630
Score = 63.5 bits (153), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 54/194 (27%), Positives = 87/194 (44%), Gaps = 26/194 (13%)
Query 73 LGGTCVNVGCIPKK-LMHYAAQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQ 131
+GGTCVN GC+P K L+ + ++++ L E + G +Q
Sbjct 181 VGGTCVNRGCVPSKALLAVSGRMRE-----------LQNEHHMKAFG-----LQVSAAGY 224
Query 132 LVQCVQSYIKQLNFSYRVGL----RSAGCTYINAAARLVGPHTVEYEVKGEKKQLTARYI 187
Q V + L R L ++ G + ++GP V+Y G+ +T + I
Sbjct 225 DRQGVADHASNLATKIRNNLTNSMKALGVDILTGFGAVLGPQKVKY---GDN-IITGKDI 280
Query 188 LIAVGGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQV 247
+IA G P++P G+ + ITSD L++ P +VG YI LE + + LG +V
Sbjct 281 IIATGSVPFVPKGIEVDGKTVITSDHALKLESVPDWIAIVGSGYIGLEFSDVYTALGSEV 340
Query 248 T-VAYRSILLRGFD 260
T + L+ GFD
Sbjct 341 TFIEALDQLMPGFD 354
> ath:AT1G48030 mtLPD1; mtLPD1 (mitochondrial lipoamide dehydrogenase
1); ATP binding / dihydrolipoyl dehydrogenase; K00382
dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=507
Score = 60.1 bits (144), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 45/178 (25%), Positives = 78/178 (43%), Gaps = 14/178 (7%)
Query 73 LGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQL 132
LGGTC+NVGCIP K + +++ + + SF + G + ++ + L
Sbjct 78 LGGTCLNVGCIPSKALLHSSHMYHEAKH--------SF----ANHGIKVSSVEVDLPAML 125
Query 133 VQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYE-VKGEKKQLTARYILIAV 191
Q + +K L + TY+ + + P+ V E + G + ++I++A
Sbjct 126 AQK-DNAVKNLTRGIEGLFKKNKVTYVKGYGKFISPNEVSVETIDGGNTIVKGKHIIVAT 184
Query 192 GGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVTV 249
G G+ + ++S SL P K +V+G YI LE +LG +VTV
Sbjct 185 GSDVKSLPGITIDEKKIVSSTGALSLSEVPKKLIVIGAGYIGLEMGSVWGRLGSEVTV 242
> tgo:TGME49_019130 glutathione reductase, putative (EC:1.8.1.7)
Length=505
Score = 60.1 bits (144), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 42/160 (26%), Positives = 77/160 (48%), Gaps = 22/160 (13%)
Query 128 CWSQLVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGP------------------H 169
W +L + +Y+ +L ++ L+ A T RL H
Sbjct 54 SWERLRESRDAYVSRLRDTFARLLKEANVTVYRGVGRLDASFDRTGKSGNSSAQRCRPRH 113
Query 170 TVEYE-VKGEKKQLTARYILIAVGGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVG 228
V + ++G+ +++TA ++LIA G R + + GA EFAI+SD F ++ P + ++G
Sbjct 114 AVLIQTLEGKVQRVTANHVLIATGTRRQVLD-IPGA-EFAISSDGFFQIQHLPRRVALIG 171
Query 229 GSYIALECAGFLSQLGYQVTVAYRSIL-LRGFDRQSAEKV 267
Y++ E G L LG V++ R+ L+ FD+++ E +
Sbjct 172 AGYVSAELGGILRHLGVDVSIFMRNQRQLKRFDKEAVESL 211
> ath:AT3G17240 mtLPD2; mtLPD2 (LIPOAMIDE DEHYDROGENASE 2); ATP
binding / dihydrolipoyl dehydrogenase; K00382 dihydrolipoamide
dehydrogenase [EC:1.8.1.4]
Length=507
Score = 58.5 bits (140), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 42/178 (23%), Positives = 76/178 (42%), Gaps = 14/178 (7%)
Query 73 LGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQL 132
LGGTC+NVGCIP K + +++ + + + + G + ++ + L
Sbjct 78 LGGTCLNVGCIPSKALLHSSHMYHEA------------KHVFANHGVKVSSVEVDLPAML 125
Query 133 VQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYE-VKGEKKQLTARYILIAV 191
Q + +K L + Y+ + + P V + + GE + ++I++A
Sbjct 126 AQK-DTAVKNLTRGVEGLFKKNKVNYVKGYGKFLSPSEVSVDTIDGENVVVKGKHIIVAT 184
Query 192 GGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVTV 249
G G+ + ++S SL P K +V+G YI LE +LG +VTV
Sbjct 185 GSDVKSLPGITIDEKKIVSSTGALSLTEIPKKLIVIGAGYIGLEMGSVWGRLGSEVTV 242
> eco:b0116 lpd, dhl, ECK0115, JW0112, lpdA; lipoamide dehydrogenase,
E3 component is part of three enzyme complexes (EC:1.8.1.4);
K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=474
Score = 58.2 bits (139), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 54/183 (29%), Positives = 76/183 (41%), Gaps = 26/183 (14%)
Query 73 LGGTCVNVGCIPKK-LMHYAAQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTC-CWS 130
LGG C+NVGCIP K L+H A +++ A + G + GEP + W
Sbjct 41 LGGVCLNVGCIPSKALLHVAKVIEEAKA--LAEHGIV--------FGEPKTDIDKIRTWK 90
Query 131 QLVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEVKGEKKQLTARYILIA 190
+ V I QL + +N + G +T+E E + K + +IA
Sbjct 91 EKV------INQLTGGLAGMAKGRKVKVVNGLGKFTGANTLEVEGENGKTVINFDNAIIA 144
Query 191 VGGR----PYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQ 246
G R P+IP R + S D LK P + LV+GG I LE LG Q
Sbjct 145 AGSRPIQLPFIPH--EDPRIW--DSTDALELKEVPERLLVMGGGIIGLEMGTVYHALGSQ 200
Query 247 VTV 249
+ V
Sbjct 201 IDV 203
> bbo:BBOV_IV007190 23.m05858; dihydrolipoamide dehydrogenase
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=481
Score = 56.6 bits (135), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 60/217 (27%), Positives = 96/217 (44%), Gaps = 39/217 (17%)
Query 73 LGGTCVNVGCIPKKLM-----HYAAQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTC 127
LGGTC+NVGCIP K + HY A + + F + G+ +
Sbjct 58 LGGTCLNVGCIPSKCLLNTSHHYKASHD--------GIAGIKFTNVEFNHGQTMS----- 104
Query 128 CWSQLVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEVKGEKKQLTARYI 187
+++++ + + IK L + G YI+ L + ++ E GE ++A+ I
Sbjct 105 SKAKILKTLDAGIKGL-------FKKNGVDYISGHGTLKSANEIQIE-GGE--TVSAKNI 154
Query 188 LIAVGGR----PYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQL 243
+IA G P + G R I+SD+ L P + +V+GG I LE A S+L
Sbjct 155 IIATGSEVTTFPGDALKIDGKR--IISSDEALVLDEVPKEMVVIGGGAIGLELASVWSRL 212
Query 244 GYQVT-VAYRSILLRGFDRQSAEKVGSCMQELEGKQG 279
G +VT V Y + L D V ++++ KQG
Sbjct 213 GAKVTIVEYANNLCHTMDHD----VSVAIKKIVEKQG 245
> pfa:PF08_0066 lipoamide dehydrogenase, putative (EC:1.8.1.4);
K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=666
Score = 55.1 bits (131), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 56/212 (26%), Positives = 89/212 (41%), Gaps = 25/212 (11%)
Query 73 LGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSF-----ERFHPSTGEPLPHMQTC 127
+GGTCVNVGCIP K + YA ++L + L L + F + + + Q
Sbjct 161 IGGTCVNVGCIPSKALLYATNKYREL----KNLDKLYYYGIHSNIFQNNKNTEIENNQLV 216
Query 128 CWS------QLVQCVQSYIKQLNF-------SYRVGLRSAGCTYINAAARLVGPHTVEYE 174
S +L + QS I +L + + S I +L+ +T++ +
Sbjct 217 SNSFQINITKLKEYTQSVIDKLRNGISHGFKTLKFNKNSEHVQVIYEHGQLLDKNTIKSK 276
Query 175 VKGEKKQLTARYILIAVGGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIAL 234
G ++ + I+IA G P IP+ V + TSD L ++G I L
Sbjct 277 KSGNTYKV--KNIIIATGSVPNIPNNVEIDDKSVFTSDMAVKLVGLKNYMSIIGMGIIGL 334
Query 235 ECAGFLSQLGYQVT-VAYRSILLRGFDRQSAE 265
E A + LG ++T + Y S LL D A+
Sbjct 335 EFADIYTALGSEITFLEYSSELLPIIDNDVAK 366
> tgo:TGME49_006470 dihydrolipoyl dehydrogenase, putative (EC:1.8.1.4);
K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=519
Score = 53.9 bits (128), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 58/207 (28%), Positives = 87/207 (42%), Gaps = 20/207 (9%)
Query 73 LGGTCVNVGCIPKKLMHYAAQLQQQLAW-DCRQLGCLSFERFHPSTGEPLPHMQTCCWSQ 131
LGGTC+NVGCIP K A L + D R FER G + + + +
Sbjct 84 LGGTCLNVGCIPSK-----AVLNISNKYVDARD----HFERL----GIKIDGL-SIDIDK 129
Query 132 LVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEVKG--EKKQLTARYILI 189
+ + Q + L R G Y +L ++VE G EK++L A +I++
Sbjct 130 MQKQKQKVVSTLTQGIEHLFRRNGVDYYVGEGKLTDSNSVEVTPNGKSEKQRLDAGHIIL 189
Query 190 AVGGR--PYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQV 247
A G P + V + I+S +L P + V+GG I LE LG +V
Sbjct 190 ATGSEASPLPGNVVPIDEKVIISSTGALALDKVPKRMAVIGGGVIGLELGSVWRNLGAEV 249
Query 248 TVA-YRSILLRGFDRQSAEKVGSCMQE 273
TV + LL D + A+ M++
Sbjct 250 TVVEFLDRLLPPVDGEVAKAFQKEMEK 276
> sce:YPL017C IRC15; Irc15p; K00382 dihydrolipoamide dehydrogenase
[EC:1.8.1.4]
Length=499
Score = 53.5 bits (127), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 56/207 (27%), Positives = 88/207 (42%), Gaps = 23/207 (11%)
Query 73 LGGTCVNVGCIPKKLMHYAAQL-----QQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTC 127
LGG + G +P K + Y + L QQ+L Q G R P+ + MQ
Sbjct 52 LGGAYLVDGAVPSKTLLYESYLYRLLQQQEL---IEQRGT----RLFPAKFD----MQAA 100
Query 128 CWSQLVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEVKGEKKQLT-ARY 186
+ ++ I++L Y+ L T A PH VE +G K + A+Y
Sbjct 101 QSA-----LKHNIEELGNVYKRELSKNNVTVYKGTAAFKDPHHVEIAQRGMKPFIVEAKY 155
Query 187 ILIAVGGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQ 246
I++A G GV + I+SD SL P + ++GG I LE A + LG +
Sbjct 156 IVVATGSAVIQCPGVAIDNDKIISSDKALSLDYIPSRFTIMGGGTIGLEIACIFNNLGSR 215
Query 247 VTVAY-RSILLRGFDRQSAEKVGSCMQ 272
VT+ +S + + D + A + +Q
Sbjct 216 VTIVESQSEICQNMDNELASATKTLLQ 242
> pfa:PFL1550w lipoamide dehydrogenase (EC:1.8.1.4); K00382 dihydrolipoamide
dehydrogenase [EC:1.8.1.4]
Length=512
Score = 52.0 bits (123), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 59/218 (27%), Positives = 85/218 (38%), Gaps = 42/218 (19%)
Query 73 LGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCL------SFERFHPSTGEPLPHMQT 126
LGGTC+N GCIP K + + + + ++ G L E H
Sbjct 59 LGGTCLNRGCIPSKSLLHISHNYYEAKTRFKECGILVDNVKLDIETMHKHKN-------- 110
Query 127 CCWSQLVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEVKGEKKQLTARY 186
+C+ + +NF Y+ +I LV HTV + + E+K++TA
Sbjct 111 -------KCMGNLSDGINFLYK----KNNVNHIIGHGSLVDEHTVLIKTEKEEKKVTAER 159
Query 187 ILIAVGGRPY-IPSG----------------VRGAREFAITSDDIFSLKTPPGKTLVVGG 229
I+IA G +P IP + E SDDI + K P ++GG
Sbjct 160 IVIATGSKPIEIPLKKLNDNNFNDADNVNDILEYDHEIIQNSDDILNFKKVPHNISIIGG 219
Query 230 SYIALECAGFLSQLGYQVTVAYRSILLRGFDRQSAEKV 267
I LE S+LG VTV + L GF KV
Sbjct 220 GVIGLEIGSVFSKLGSDVTVFEYNERLCGFLDADVSKV 257
> eco:b3962 sthA, ECK3954, JW5551, sth, udhA; pyridine nucleotide
transhydrogenase, soluble (EC:1.6.1.1); K00322 NAD(P) transhydrogenase
[EC:1.6.1.1]
Length=466
Score = 51.6 bits (122), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 47/198 (23%), Positives = 79/198 (39%), Gaps = 16/198 (8%)
Query 72 GLGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQ 131
+GG C + G IP K + +A + + + ++ L S + L H +Q
Sbjct 40 NVGGGCTHWGTIPSKALRHA--VSRIIEFNQNPLYSDHSRLLRSSFADILNHADNVI-NQ 96
Query 132 LVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEV-KGEKKQLTARYILIA 190
+ Q + ++ + C + AR V HT+ + G + LTA +IA
Sbjct 97 QTRMRQGFYERNH-----------CEILQGNARFVDEHTLALDCPDGSVETLTAEKFVIA 145
Query 191 VGGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVT-V 249
G RPY P+ V SD I S+ P L+ G I E A + +V +
Sbjct 146 CGSRPYHPTDVDFTHPRIYDSDSILSMHHEPRHVLIYGAGVIGCEYASIFRGMDVKVDLI 205
Query 250 AYRSILLRGFDRQSAEKV 267
R LL D++ ++ +
Sbjct 206 NTRDRLLAFLDQEMSDSL 223
> mmu:13382 Dld, AI315664, AI746344; dihydrolipoamide dehydrogenase
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=509
Score = 51.6 bits (122), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 41/177 (23%), Positives = 74/177 (41%), Gaps = 13/177 (7%)
Query 73 LGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQL 132
LGGTC+NVGCIP K + + ++ + S G +P ++ ++
Sbjct 76 LGGTCLNVGCIPSKALLNNSHYYH-----------MAHGKDFASRGIEIPEVR-LNLEKM 123
Query 133 VQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVE-YEVKGEKKQLTARYILIAV 191
++ S +K L + ++N ++ G + V + G + + + IL+A
Sbjct 124 MEQKHSAVKALTGGIAHLFKQNKVVHVNGFGKITGKNQVTATKADGSTQVIDTKNILVAT 183
Query 192 GGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQVT 248
G G+ + ++S SLK P K +V+G I +E +LG VT
Sbjct 184 GSEVTPFPGITIDEDTIVSSTGALSLKKVPEKLVVIGAGVIGVELGSVWQRLGADVT 240
> tgo:TGME49_105980 dihydrolipoyl dehydrogenase protein, putative
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=636
Score = 50.4 bits (119), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 50/199 (25%), Positives = 84/199 (42%), Gaps = 17/199 (8%)
Query 74 GGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGCLSFERFHPSTGEPLPHMQTCCWSQLV 133
GGTCVN GC+P K + AA+ + ++ + L + + +P + +
Sbjct 176 GGTCVNRGCVPSKALLAAAR-RVKMLRNKHHLSAMGLQVEGEIKVDP---------TGVG 225
Query 134 QCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVG-PHTVEYEVKGEKKQ-----LTARYI 187
+ + ++ L S G +A + G P V E L + +
Sbjct 226 NHARGVVDKVRSGLVSSLASHGIALFDARGVMDGEPGRVVLERTAGSPASLPPFLRTKNV 285
Query 188 LIAVGGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGYQV 247
++A G P+IP+G + + +TSD SL P + +VG YI LE + LG +V
Sbjct 286 ILAPGSLPFIPAGTKEEQFSVMTSDTCVSLPWLPSEICIVGSGYIGLEFMDVFTSLGSEV 345
Query 248 T-VAYRSILLRGFDRQSAE 265
V LL G D++ A+
Sbjct 346 VMVEAGPRLLPGVDKEVAK 364
> dre:399479 dldh, wu:fb24b05; dihydrolipoamide dehydrogenase
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=507
Score = 49.3 bits (116), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 43/183 (23%), Positives = 73/183 (39%), Gaps = 26/183 (14%)
Query 73 LGGTCVNVGCIPKKLM---HYAAQLQQQLAWDCRQLGC----LSFERFHPSTGEPLPHMQ 125
LGGTC+NVGCIP K + Y + ++ R + L+ E+
Sbjct 75 LGGTCLNVGCIPSKALLNNSYLYHMAHGKDFESRGIEIQGISLNLEKMMAQK-------- 126
Query 126 TCCWSQLVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEVKGEKKQLTAR 185
S V+ + I L + T++N + G + V + ++ + +
Sbjct 127 ----SGAVKALTGGIAHL-------FKQNKVTHVNGFGTITGKNQVTAKTADGEQVINTK 175
Query 186 YILIAVGGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGY 245
ILIA G G+ + ++S SLK P + +V+G I +E +LG
Sbjct 176 NILIATGSEVTPFPGIEIDEDSVVSSTGALSLKNVPEELIVIGAGVIGVELGSVWQRLGA 235
Query 246 QVT 248
+VT
Sbjct 236 KVT 238
> sce:YFL018C LPD1, HPD1; Dihydrolipoamide dehydrogenase, the
lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase
and 2-oxoglutarate dehydrogenase multi-enzyme complexes
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=499
Score = 47.0 bits (110), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 49/184 (26%), Positives = 78/184 (42%), Gaps = 19/184 (10%)
Query 73 LGGTCVNVGCIPKKLMHYAAQLQQQLAWDCRQLGC-------LSFERFHPSTGEPLPHMQ 125
LGGTC+NVGCIP K + + L Q+ + ++ G ++ F + + +
Sbjct 61 LGGTCLNVGCIPSKALLNNSHLFHQMHTEAQKRGIDVNGDIKINVANFQKAKDDAV---- 116
Query 126 TCCWSQLVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEVKGEKKQLTAR 185
QL ++ K+ +Y G G R+ +E VK E L +
Sbjct 117 ----KQLTGGIELLFKKNKVTYYKG---NGSFEDETKIRVTPVDGLEGTVK-EDHILDVK 168
Query 186 YILIAVGGRPYIPSGVRGAREFAITSDDIFSLKTPPGKTLVVGGSYIALECAGFLSQLGY 245
I++A G G+ E ++S SLK P + ++GG I LE S+LG
Sbjct 169 NIIVATGSEVTPFPGIEIDEEKIVSSTGALSLKEIPKRLTIIGGGIIGLEMGSVYSRLGS 228
Query 246 QVTV 249
+VTV
Sbjct 229 KVTV 232
Score = 33.9 bits (76), Expect = 0.72, Method: Compositional matrix adjust.
Identities = 27/114 (23%), Positives = 49/114 (42%), Gaps = 16/114 (14%)
Query 122 PHMQTCCWSQLVQCVQSYIKQLNFSYRVGLRSAGCTYINAAARLVGPHTVEYEVKGEK-- 179
P + ++ + Q ++K+ +++ T + +A R + VE V+ K
Sbjct 237 PQIGASMDGEVAKATQKFLKKQGLDFKL------STKVISAKRNDDKNVVEIVVEDTKTN 290
Query 180 --KQLTARYILIAVGGRPYI------PSGVRGAREFAITSDDIFSLKTPPGKTL 225
+ L A +L+AVG RPYI G+ + + DD F+ K P K +
Sbjct 291 KQENLEAEVLLVAVGRRPYIAGLGAEKIGLEVDKRGRLVIDDQFNSKFPHIKVV 344
Lambda K H
0.317 0.131 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 10720471776
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
Posted date: Sep 16, 2011 8:45 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40