bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
164,496 sequences; 82,071,388 total letters
Query= Eace_0220_orf2
Length=142
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_008720 phosphatase, putative (EC:3.1.3.48) 159 3e-39
pfa:PF11_0139 PRL; protein tyrosine phosphatase; K01104 protei... 149 3e-36
bbo:BBOV_IV011660 23.m06279; tyrosine phosphatase (EC:3.1.3.48... 147 7e-36
tpv:TP01_1140 protein tyrosine phosphatase; K01104 protein-tyr... 146 2e-35
dre:406460 ptp4a3, wu:fc54b05, wu:fv52d11, zgc:77109; protein ... 125 3e-29
xla:379932 ptp4a2, MGC53390; protein tyrosine phosphatase 4a2 ... 124 1e-28
xla:443874 ptp4a2, MGC132077, MGC80084, hh13, hh7-2, ov-1, prl... 123 1e-28
mmu:19244 Ptp4a2, MGC102154, MGC103400, Prl-2; protein tyrosin... 122 3e-28
cel:T19D2.2 prl-1; hypothetical protein; K01104 protein-tyrosi... 122 5e-28
mmu:19245 Ptp4a3, AV088979, Prl-3, pPtp4a3; protein tyrosine p... 122 5e-28
xla:432351 ptp4a3, prl-3, prl3, ptpcaax3; protein tyrosine pho... 121 7e-28
xla:446679 ptp4a1, MGC83351, hh72, prl-1, prl1, ptp(caax1), pt... 120 2e-27
dre:449541 zgc:91861 (EC:3.1.3.48); K01104 protein-tyrosine ph... 119 4e-27
xla:432352 prl-1; xPRL-1; K01104 protein-tyrosine phosphatase ... 118 7e-27
mmu:19243 Ptp4a1, AA415290, AU019864, C130021B01, MGC102117, M... 115 3e-26
mmu:100044742 protein tyrosine phosphatase type IVA 1-like; K0... 115 3e-26
hsa:7803 PTP4A1, DKFZp779M0721, HH72, PRL-1, PRL1, PTP(CAAX1),... 115 3e-26
dre:493615 ptp4a1, zgc:101726; protein tyrosine phosphatase ty... 115 6e-26
dre:567691 fc14a08, wu:fc14a08; si:ch211-251p5.5 114 1e-25
dre:334483 PTP4A2, wu:fi84b06; zgc:101724 113 2e-25
xla:734842 hypothetical protein MGC131305 84.7 9e-17
hsa:8073 PTP4A2, HH13, HH7-2, HU-PP-1, OV-1, PRL-2, PRL2, PTP4... 82.8 4e-16
hsa:11156 PTP4A3, PRL-3, PRL-R, PRL3; protein tyrosine phospha... 81.6 7e-16
dre:393148 cdc14b, MGC55844, cdc14a, zgc:55844; CDC14 cell div... 65.9 4e-11
dre:394124 cdc14aa, CDC14A, MGC63654, zgc:63654; CDC14 cell di... 60.5 2e-09
dre:436735 zgc:92902; K14165 dual specificity phosphatase [EC:... 58.9 5e-09
sce:YFR028C CDC14, OAF3; Cdc14p (EC:3.1.3.48); K06639 cell div... 57.8 1e-08
mmu:218294 Cdc14b, 2810432N10Rik, A530086E13Rik, AA472821, CDC... 56.6 2e-08
dre:565969 cdc14ab, si:dkey-168j9.1; CDC14 cell division cycle... 56.6 3e-08
hsa:8555 CDC14B, CDC14B3, Cdc14B1, Cdc14B2, hCDC14B; CDC14 cel... 55.1 7e-08
mmu:229776 Cdc14a, A830059A17Rik, CDC14A2, CDC14a1, Cdc14; CDC... 55.1 8e-08
hsa:8556 CDC14A, cdc14, hCDC14; CDC14 cell division cycle 14 h... 54.3 1e-07
xla:403393 cdc14a, xcdc14a; CDC14 cell division cycle 14 homol... 53.9 1e-07
cpv:cgd7_4470 CDC14 phosphatase ; K06639 cell division cycle 1... 53.9 2e-07
hsa:54935 DUSP23, DUSP25, FLJ20442, LDP-3, MOSP, RP11-190A12.1... 52.4 5e-07
dre:323834 fc11c10, wu:fc11c10; si:dkeyp-95d10.1 52.4 5e-07
xla:407839 cdc14b, MGC81657, cdc14beta, xcdc14b; CDC14 cell di... 52.4 5e-07
xla:495348 dusp23; dual specificity phosphatase 23; K14165 dua... 52.0 6e-07
cel:C17G10.4 cdc-14; Cell Division Cycle related family member... 52.0 7e-07
mmu:68440 Dusp23, 1300005N15Rik, LDP-3, MGC73633; dual specifi... 48.5 7e-06
dre:565773 ptpdc1, zgc:158271; protein tyrosine phosphatase do... 45.4 6e-05
tgo:TGME49_114430 dual specificity protein phosphatase CDC14A,... 43.9 2e-04
mmu:218232 Ptpdc1, AI843923, AW456874, Naa-1; protein tyrosine... 42.7 3e-04
hsa:138639 PTPDC1, FLJ42922, PTP9Q22; protein tyrosine phospha... 42.4 5e-04
dre:570928 si:ch73-142c19.2 42.4 5e-04
ath:AT5G39400 PTEN1; PTEN1; phosphatase; K01110 phosphatidylin... 42.0 6e-04
dre:393862 MGC77752; zgc:77752 40.8 0.001
hsa:5728 PTEN, 10q23del, BZS, DEC, GLM2, MGC11227, MHAM, MMAC1... 39.3 0.004
mmu:19211 Pten, 2310035O07Rik, A130070J02Rik, AI463227, B43020... 39.3 0.004
xla:444752 dusp5, MGC84792; dual specificity phosphatase 5; K0... 38.5 0.007
> tgo:TGME49_008720 phosphatase, putative (EC:3.1.3.48)
Length=483
Score = 159 bits (402), Expect = 3e-39, Method: Composition-based stats.
Identities = 78/139 (56%), Positives = 98/139 (70%), Gaps = 0/139 (0%)
Query 4 VLNVPTLIESRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIR 63
V+N PT IE+ K LI DAP+ ENL AY+ ++ VTDLVRTC TYD+ V+ +GIR
Sbjct 321 VMNTPTRIEAGRQKFLIFDAPSQENLPAYIEEMRAYEVTDLVRTCERTYDDKTVLASGIR 380
Query 64 VHDLTFPDGEAPPAEVIARWRALAAQAQAEGGVLAVHCVAGLGRGPVLVAVSLIDSGFEA 123
H+L FPDGEAPP +VI W L + G +A+HCVAGLGR PVLVA++LI+ G +
Sbjct 381 PHELIFPDGEAPPDDVIDEWLTLCNAVSQQRGAIAIHCVAGLGRAPVLVAIALIEKGMDP 440
Query 124 EEAVNFIRSRRKGAINRRQ 142
+A+ FIR RRKGAINRRQ
Sbjct 441 MDAIMFIRERRKGAINRRQ 459
> pfa:PF11_0139 PRL; protein tyrosine phosphatase; K01104 protein-tyrosine
phosphatase [EC:3.1.3.48]
Length=218
Score = 149 bits (376), Expect = 3e-36, Method: Compositional matrix adjust.
Identities = 71/139 (51%), Positives = 94/139 (67%), Gaps = 0/139 (0%)
Query 4 VLNVPTLIESRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIR 63
VLN PT IE +K LILDAPTN+ L Y+ ++ VTDLVRTC TY++G + AGI
Sbjct 57 VLNHPTKIEHGKIKILILDAPTNDLLPLYIKEMKNYNVTDLVRTCERTYNDGEIQDAGIN 116
Query 64 VHDLTFPDGEAPPAEVIARWRALAAQAQAEGGVLAVHCVAGLGRGPVLVAVSLIDSGFEA 123
VH+L FPDG+AP ++++ W + +AVHCVAGLGR PVL ++ LI+ G +
Sbjct 117 VHELIFPDGDAPTEDIVSNWLNIVNNVIKNNCAVAVHCVAGLGRAPVLASIVLIEFGMDP 176
Query 124 EEAVNFIRSRRKGAINRRQ 142
+A+ FIR RRKGAIN+RQ
Sbjct 177 IDAIVFIRDRRKGAINKRQ 195
> bbo:BBOV_IV011660 23.m06279; tyrosine phosphatase (EC:3.1.3.48);
K01104 protein-tyrosine phosphatase [EC:3.1.3.48]
Length=172
Score = 147 bits (372), Expect = 7e-36, Method: Compositional matrix adjust.
Identities = 68/141 (48%), Positives = 91/141 (64%), Gaps = 0/141 (0%)
Query 2 GMVLNVPTLIESRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAG 61
VLN PT IE ++ LILDAP N N++ YL +++ GVT LVRTC YD+ +I
Sbjct 9 SYVLNKPTKIEFHKLRILILDAPNNSNVKLYLHEMLDFGVTYLVRTCETNYDDSAIIEEN 68
Query 62 IRVHDLTFPDGEAPPAEVIARWRALAAQAQAEGGVLAVHCVAGLGRGPVLVAVSLIDSGF 121
I + +L F DGE P E++A W L + A G +AVHCVAGLGR PVL ++L++ G
Sbjct 69 IAIKELIFNDGEPPSDEIVAEWLKLVKEVVASNGSVAVHCVAGLGRAPVLACIALVEYGM 128
Query 122 EAEEAVNFIRSRRKGAINRRQ 142
+A+ F+R RRKGAINR+Q
Sbjct 129 HPLDAICFVRERRKGAINRKQ 149
> tpv:TP01_1140 protein tyrosine phosphatase; K01104 protein-tyrosine
phosphatase [EC:3.1.3.48]
Length=168
Score = 146 bits (369), Expect = 2e-35, Method: Compositional matrix adjust.
Identities = 66/139 (47%), Positives = 92/139 (66%), Gaps = 0/139 (0%)
Query 4 VLNVPTLIESRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIR 63
VLN PT IE + +K LILDAP N NL+ Y+ ++++ GV+ LVRTC Y++ ++ I
Sbjct 7 VLNKPTRIEYQKLKILILDAPNNSNLKLYIKEMLEFGVSCLVRTCESNYNDQLLLDNQIE 66
Query 64 VHDLTFPDGEAPPAEVIARWRALAAQAQAEGGVLAVHCVAGLGRGPVLVAVSLIDSGFEA 123
V DL F DG+ PP +++ RW L +AVHCVAGLGR PVL ++L++ G +
Sbjct 67 VKDLFFNDGDPPPYDIVTRWLELIHHCLETNSAIAVHCVAGLGRAPVLACIALVEYGMQP 126
Query 124 EEAVNFIRSRRKGAINRRQ 142
+A+ F+R RRKGAINRRQ
Sbjct 127 LDAICFVRDRRKGAINRRQ 145
> dre:406460 ptp4a3, wu:fc54b05, wu:fv52d11, zgc:77109; protein
tyrosine phosphatase type IVA, member 3 (EC:3.1.3.48); K01104
protein-tyrosine phosphatase [EC:3.1.3.48]
Length=173
Score = 125 bits (315), Expect = 3e-29, Method: Compositional matrix adjust.
Identities = 65/142 (45%), Positives = 91/142 (64%), Gaps = 4/142 (2%)
Query 5 LNVPTLIE--SRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGI 62
+N P +E + ++ LI PTN L +++ L + GVT +VR C TYD+ P+ GI
Sbjct 4 MNRPAPVEVCYKNMRFLITHNPTNSTLSSFIEDLKKYGVTTVVRVCEITYDKTPLEKNGI 63
Query 63 RVHDLTFPDGEAPPAEVIARWRALAAQAQAE--GGVLAVHCVAGLGRGPVLVAVSLIDSG 120
V D F DG PP++V+ W +L + E G +AVHCVAGLGR PVLVAV+LI+SG
Sbjct 64 TVVDWPFDDGAPPPSKVVEDWLSLLKRRFIEEPGCCVAVHCVAGLGRAPVLVAVALIESG 123
Query 121 FEAEEAVNFIRSRRKGAINRRQ 142
+ E+A+ FIR +R+GAIN +Q
Sbjct 124 MKYEDAIQFIRQKRRGAINSKQ 145
> xla:379932 ptp4a2, MGC53390; protein tyrosine phosphatase 4a2
(EC:3.1.3.48); K01104 protein-tyrosine phosphatase [EC:3.1.3.48]
Length=167
Score = 124 bits (310), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 63/137 (45%), Positives = 82/137 (59%), Gaps = 2/137 (1%)
Query 8 PTLIESRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDL 67
P I ++ LI PTN L + +L + GVT LVR C TYD+ PV GI+V D
Sbjct 6 PVEISHECMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIQVLDW 65
Query 68 TFPDGEAPPAEVIARWRALAAQAQAE--GGVLAVHCVAGLGRGPVLVAVSLIDSGFEAEE 125
F DG PP +++ W L E G +AVHCVAGLGR PVLVA++LI+ G + E+
Sbjct 66 PFDDGAPPPTQIVDDWLNLLKTKFREEAGCCIAVHCVAGLGRAPVLVALALIECGMKYED 125
Query 126 AVNFIRSRRKGAINRRQ 142
AV FIR +R+GA N +Q
Sbjct 126 AVQFIRQKRRGAFNSKQ 142
> xla:443874 ptp4a2, MGC132077, MGC80084, hh13, hh7-2, ov-1, prl-2,
prl2, ptp-iv1b, ptpcaax2; protein tyrosine phosphatase
type IVA, member 2 (EC:3.1.3.48)
Length=167
Score = 123 bits (309), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 63/137 (45%), Positives = 82/137 (59%), Gaps = 2/137 (1%)
Query 8 PTLIESRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDL 67
P I ++ LI PTN L + +L + GVT LVR C TYD+ PV GI+V D
Sbjct 6 PVEISHECMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIQVLDW 65
Query 68 TFPDGEAPPAEVIARWRALAAQAQAE--GGVLAVHCVAGLGRGPVLVAVSLIDSGFEAEE 125
F DG PP +++ W L E G +AVHCVAGLGR PVLVA++LI+ G + E+
Sbjct 66 PFDDGAPPPTQIVDDWLNLLKTKFREEAGCCIAVHCVAGLGRAPVLVALALIECGMKYED 125
Query 126 AVNFIRSRRKGAINRRQ 142
AV FIR +R+GA N +Q
Sbjct 126 AVQFIRQKRRGAFNSKQ 142
> mmu:19244 Ptp4a2, MGC102154, MGC103400, Prl-2; protein tyrosine
phosphatase 4a2 (EC:3.1.3.48); K01104 protein-tyrosine phosphatase
[EC:3.1.3.48]
Length=167
Score = 122 bits (307), Expect = 3e-28, Method: Compositional matrix adjust.
Identities = 63/137 (45%), Positives = 81/137 (59%), Gaps = 2/137 (1%)
Query 8 PTLIESRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDL 67
P I ++ LI PTN L + +L + GVT LVR C TYD+ PV GI V D
Sbjct 6 PVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDW 65
Query 68 TFPDGEAPPAEVIARWRALAAQAQAE--GGVLAVHCVAGLGRGPVLVAVSLIDSGFEAEE 125
F DG PP +++ W L E G +AVHCVAGLGR PVLVA++LI+ G + E+
Sbjct 66 PFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECGMKYED 125
Query 126 AVNFIRSRRKGAINRRQ 142
AV FIR +R+GA N +Q
Sbjct 126 AVQFIRQKRRGAFNSKQ 142
> cel:T19D2.2 prl-1; hypothetical protein; K01104 protein-tyrosine
phosphatase [EC:3.1.3.48]
Length=190
Score = 122 bits (305), Expect = 5e-28, Method: Compositional matrix adjust.
Identities = 62/137 (45%), Positives = 87/137 (63%), Gaps = 2/137 (1%)
Query 8 PTLIESRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDL 67
P+ I ++ LI D P N ++Q+Y+ +L + G +VR C PTYD + AGI V D
Sbjct 24 PSEIAWGKMRFLITDRPNNSSIQSYIEELEKHGARAVVRVCEPTYDTLALKEAGIDVLDW 83
Query 68 TFPDGEAPPAEVIARWRALAAQAQAE--GGVLAVHCVAGLGRGPVLVAVSLIDSGFEAEE 125
F DG PP EVI W L + E +AVHCVAGLGR PVLVA++LI++G + E+
Sbjct 84 QFSDGSPPPPEVIKSWFQLCMTSFKEHPDKSIAVHCVAGLGRAPVLVAIALIEAGMKYED 143
Query 126 AVNFIRSRRKGAINRRQ 142
AV IR++R+GA+N++Q
Sbjct 144 AVEMIRTQRRGALNQKQ 160
> mmu:19245 Ptp4a3, AV088979, Prl-3, pPtp4a3; protein tyrosine
phosphatase 4a3 (EC:3.1.3.48); K01104 protein-tyrosine phosphatase
[EC:3.1.3.48]
Length=173
Score = 122 bits (305), Expect = 5e-28, Method: Compositional matrix adjust.
Identities = 63/144 (43%), Positives = 86/144 (59%), Gaps = 2/144 (1%)
Query 1 AGMVLNVPTLIESRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGA 60
A M P + R ++ LI P+N L ++ L + G T +VR C TYD+ P+
Sbjct 2 ARMNRPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKD 61
Query 61 GIRVHDLTFPDGEAPPAEVIARWRAL--AAQAQAEGGVLAVHCVAGLGRGPVLVAVSLID 118
GI V D F DG PP +V+ W +L A G +AVHCVAGLGR PVLVA++LI+
Sbjct 62 GITVVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGSCVAVHCVAGLGRAPVLVALALIE 121
Query 119 SGFEAEEAVNFIRSRRKGAINRRQ 142
SG + E+A+ FIR +R+GAIN +Q
Sbjct 122 SGMKYEDAIQFIRQKRRGAINSKQ 145
> xla:432351 ptp4a3, prl-3, prl3, ptpcaax3; protein tyrosine phosphatase
type IVA, member 3 (EC:3.1.3.48); K01104 protein-tyrosine
phosphatase [EC:3.1.3.48]
Length=173
Score = 121 bits (304), Expect = 7e-28, Method: Compositional matrix adjust.
Identities = 62/142 (43%), Positives = 87/142 (61%), Gaps = 4/142 (2%)
Query 5 LNVPTLIE--SRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGI 62
+N P +E + ++ LI PTN L ++ L + G T +VR C TYD+ P+ GI
Sbjct 4 INRPAPVEVCYKNMRFLITHNPTNATLNTFIEDLKKYGATTVVRVCEITYDKTPLEKDGI 63
Query 63 RVHDLTFPDGEAPPAEVIARWRALAAQAQAE--GGVLAVHCVAGLGRGPVLVAVSLIDSG 120
V D F DG PP++++ W L E G +AVHCVAGLGR PVLVA++LI+SG
Sbjct 64 TVMDWPFDDGAPPPSKIVDDWLNLLKTKFCEDPGCCVAVHCVAGLGRAPVLVALALIESG 123
Query 121 FEAEEAVNFIRSRRKGAINRRQ 142
+ E+A+ FIR +R+GAIN +Q
Sbjct 124 MKYEDAIQFIRQKRRGAINSKQ 145
> xla:446679 ptp4a1, MGC83351, hh72, prl-1, prl1, ptp(caax1),
ptpcaax1; protein tyrosine phosphatase type IVA, member 1 (EC:3.1.3.48);
K01104 protein-tyrosine phosphatase [EC:3.1.3.48]
Length=173
Score = 120 bits (300), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 62/137 (45%), Positives = 83/137 (60%), Gaps = 2/137 (1%)
Query 8 PTLIESRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDL 67
P I + ++ LI PTN L ++ +L + GVT LVR C TYD V GI+V D
Sbjct 9 PVEITYKNMRFLITHNPTNATLNKFIEELKKYGVTTLVRVCEATYDTALVEKEGIQVLDW 68
Query 68 TFPDGEAPPAEVIARWRALAAQAQAE--GGVLAVHCVAGLGRGPVLVAVSLIDSGFEAEE 125
F DG P ++++ W L E G +AVHCVAGLGR PVLVA++LI+SG + E+
Sbjct 69 PFDDGAPPSSQIVDDWLNLLKVKFREEPGCCIAVHCVAGLGRAPVLVALALIESGMKYED 128
Query 126 AVNFIRSRRKGAINRRQ 142
AV FIR +R+GA N +Q
Sbjct 129 AVQFIRQKRRGAFNSKQ 145
> dre:449541 zgc:91861 (EC:3.1.3.48); K01104 protein-tyrosine
phosphatase [EC:3.1.3.48]
Length=168
Score = 119 bits (298), Expect = 4e-27, Method: Compositional matrix adjust.
Identities = 62/137 (45%), Positives = 81/137 (59%), Gaps = 2/137 (1%)
Query 8 PTLIESRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDL 67
P I ++ LI PTN L + +L GV LVR C TYD+ PV GI V D
Sbjct 6 PVEITYECMRFLITHNPTNSQLAKFTEELKSFGVQTLVRVCESTYDKAPVEKEGIEVLDW 65
Query 68 TFPDGEAPPAEVIARW-RALAAQAQAE-GGVLAVHCVAGLGRGPVLVAVSLIDSGFEAEE 125
F DG +PP +++ W L + + E G +AVHCVAGLGR PVLVA++LI+ G E+
Sbjct 66 PFDDGCSPPEQIVDDWLNLLKCKFKDEPGCCIAVHCVAGLGRAPVLVAIALIECGMMYED 125
Query 126 AVNFIRSRRKGAINRRQ 142
AV FIR +R+GA N +Q
Sbjct 126 AVQFIRQKRRGAFNAKQ 142
> xla:432352 prl-1; xPRL-1; K01104 protein-tyrosine phosphatase
[EC:3.1.3.48]
Length=173
Score = 118 bits (295), Expect = 7e-27, Method: Compositional matrix adjust.
Identities = 61/137 (44%), Positives = 81/137 (59%), Gaps = 2/137 (1%)
Query 8 PTLIESRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDL 67
P I + ++ LI PTN L ++ +L + GVT LVR C TYD V GI+V D
Sbjct 9 PVEITYKNMRFLITHNPTNATLNKFIEELKKFGVTTLVRVCEATYDTALVEKEGIQVLDW 68
Query 68 TFPDGEAPPAEVIARWRALAAQAQAE--GGVLAVHCVAGLGRGPVLVAVSLIDSGFEAEE 125
F DG P +++ W L E G + VHCVAGLGR PVLVA++LI+SG + E+
Sbjct 69 PFDDGAPPSNQIVDDWLNLLKVKFREEPGCCITVHCVAGLGRAPVLVALALIESGMKYED 128
Query 126 AVNFIRSRRKGAINRRQ 142
AV FIR +R+GA N +Q
Sbjct 129 AVQFIRQKRRGAFNSKQ 145
> mmu:19243 Ptp4a1, AA415290, AU019864, C130021B01, MGC102117,
MGC25304, Prl-1; protein tyrosine phosphatase 4a1 (EC:3.1.3.48);
K01104 protein-tyrosine phosphatase [EC:3.1.3.48]
Length=173
Score = 115 bits (289), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 59/137 (43%), Positives = 81/137 (59%), Gaps = 2/137 (1%)
Query 8 PTLIESRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDL 67
P + + ++ LI PTN L ++ +L + GVT +VR C TYD V GI V D
Sbjct 9 PVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDW 68
Query 68 TFPDGEAPPAEVIARWRALAAQAQAE--GGVLAVHCVAGLGRGPVLVAVSLIDSGFEAEE 125
F DG P +++ W +L E G +AVHCVAGLGR PVLVA++LI+ G + E+
Sbjct 69 PFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYED 128
Query 126 AVNFIRSRRKGAINRRQ 142
AV FIR +R+GA N +Q
Sbjct 129 AVQFIRQKRRGAFNSKQ 145
> mmu:100044742 protein tyrosine phosphatase type IVA 1-like;
K01104 protein-tyrosine phosphatase [EC:3.1.3.48]
Length=173
Score = 115 bits (289), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 59/137 (43%), Positives = 81/137 (59%), Gaps = 2/137 (1%)
Query 8 PTLIESRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDL 67
P + + ++ LI PTN L ++ +L + GVT +VR C TYD V GI V D
Sbjct 9 PVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDW 68
Query 68 TFPDGEAPPAEVIARWRALAAQAQAE--GGVLAVHCVAGLGRGPVLVAVSLIDSGFEAEE 125
F DG P +++ W +L E G +AVHCVAGLGR PVLVA++LI+ G + E+
Sbjct 69 PFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYED 128
Query 126 AVNFIRSRRKGAINRRQ 142
AV FIR +R+GA N +Q
Sbjct 129 AVQFIRQKRRGAFNSKQ 145
> hsa:7803 PTP4A1, DKFZp779M0721, HH72, PRL-1, PRL1, PTP(CAAX1),
PTPCAAX1; protein tyrosine phosphatase type IVA, member 1
(EC:3.1.3.48); K01104 protein-tyrosine phosphatase [EC:3.1.3.48]
Length=173
Score = 115 bits (289), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 59/137 (43%), Positives = 81/137 (59%), Gaps = 2/137 (1%)
Query 8 PTLIESRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDL 67
P + + ++ LI PTN L ++ +L + GVT +VR C TYD V GI V D
Sbjct 9 PVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDW 68
Query 68 TFPDGEAPPAEVIARWRALAAQAQAE--GGVLAVHCVAGLGRGPVLVAVSLIDSGFEAEE 125
F DG P +++ W +L E G +AVHCVAGLGR PVLVA++LI+ G + E+
Sbjct 69 PFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYED 128
Query 126 AVNFIRSRRKGAINRRQ 142
AV FIR +R+GA N +Q
Sbjct 129 AVQFIRQKRRGAFNSKQ 145
> dre:493615 ptp4a1, zgc:101726; protein tyrosine phosphatase
type IVA, member 1 (EC:3.1.3.48); K01104 protein-tyrosine phosphatase
[EC:3.1.3.48]
Length=173
Score = 115 bits (287), Expect = 6e-26, Method: Compositional matrix adjust.
Identities = 59/137 (43%), Positives = 81/137 (59%), Gaps = 2/137 (1%)
Query 8 PTLIESRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDL 67
P I + ++ LI PTN L ++ +L + GVT +VR C TYD V+ GI+V D
Sbjct 9 PVEITYKNMRFLITHNPTNATLHKFIEELKKYGVTTVVRVCEATYDANLVVKEGIQVLDW 68
Query 68 TFPDGEAPPAEVIARWRALAAQAQAE--GGVLAVHCVAGLGRGPVLVAVSLIDSGFEAEE 125
F DG P +++ W L E G +AVHCVAGLGR PVLVA++LI+ G + E+
Sbjct 69 PFDDGAPPSNQIVDDWLNLLRVKFREEPGCCIAVHCVAGLGRAPVLVALALIECGMKYED 128
Query 126 AVNFIRSRRKGAINRRQ 142
AV FIR +R+ A N +Q
Sbjct 129 AVQFIRQKRRRAFNSKQ 145
> dre:567691 fc14a08, wu:fc14a08; si:ch211-251p5.5
Length=173
Score = 114 bits (285), Expect = 1e-25, Method: Compositional matrix adjust.
Identities = 56/137 (40%), Positives = 82/137 (59%), Gaps = 2/137 (1%)
Query 8 PTLIESRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDL 67
P + ++ +I PTN+ L ++ L + +VR C TYD+ P+ GI V D
Sbjct 9 PVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDW 68
Query 68 TFPDGEAPPAEVIARWRALAAQAQAE--GGVLAVHCVAGLGRGPVLVAVSLIDSGFEAEE 125
F DG PP +++ W +L ++ +E G +AVHCVAGLGR PVLVAV+LI+ G + EE
Sbjct 69 PFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEE 128
Query 126 AVNFIRSRRKGAINRRQ 142
A++ IR +R GA N +Q
Sbjct 129 AIHLIRLKRHGAFNSKQ 145
> dre:334483 PTP4A2, wu:fi84b06; zgc:101724
Length=168
Score = 113 bits (282), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 60/142 (42%), Positives = 81/142 (57%), Gaps = 4/142 (2%)
Query 5 LNVPTLIE--SRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGI 62
+N P +E ++ LI PTN L + +L + V LVR C TYD V GI
Sbjct 1 MNRPAAVEISYDCMRFLITHNPTNSTLNKFTEELKKFEVNTLVRVCEATYDTALVQKEGI 60
Query 63 RVHDLTFPDGEAPPAEVIARWRALAAQAQAE--GGVLAVHCVAGLGRGPVLVAVSLIDSG 120
+V D F DG +PP ++ W L E G +AVHCVAGLGR PVLVA++L++ G
Sbjct 61 QVFDWPFDDGASPPTRIVDDWLNLLKTKFREEPGCCIAVHCVAGLGRAPVLVALALLECG 120
Query 121 FEAEEAVNFIRSRRKGAINRRQ 142
+ EEAV +IR +R+GA N +Q
Sbjct 121 MKYEEAVMYIRQKRRGAFNAKQ 142
> xla:734842 hypothetical protein MGC131305
Length=108
Score = 84.7 bits (208), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 40/79 (50%), Positives = 54/79 (68%), Gaps = 2/79 (2%)
Query 66 DLTFPDGEAPPAEVIARWRALAAQAQAE--GGVLAVHCVAGLGRGPVLVAVSLIDSGFEA 123
D F DG PP++++ W L E G +AVHCVAGLGR PVLVA++LI+SG +
Sbjct 2 DWPFDDGAPPPSKIVDDWLNLLKTKFCEDPGCCVAVHCVAGLGRAPVLVALALIESGMKY 61
Query 124 EEAVNFIRSRRKGAINRRQ 142
E+A+ FIR +R+GAIN +Q
Sbjct 62 EDAIQFIRQKRRGAINSKQ 80
> hsa:8073 PTP4A2, HH13, HH7-2, HU-PP-1, OV-1, PRL-2, PRL2, PTP4A,
PTPCAAX2, ptp-IV1a, ptp-IV1b; protein tyrosine phosphatase
type IVA, member 2 (EC:3.1.3.48); K01104 protein-tyrosine
phosphatase [EC:3.1.3.48]
Length=142
Score = 82.8 bits (203), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 44/102 (43%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Query 8 PTLIESRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDL 67
P I ++ LI PTN L + +L + GVT LVR C TYD+ PV GI V D
Sbjct 6 PVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDW 65
Query 68 TFPDGEAPPAEVIARWRALAAQAQAE--GGVLAVHCVAGLGR 107
F DG PP +++ W L E G +AVHCVAGLGR
Sbjct 66 PFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGR 107
> hsa:11156 PTP4A3, PRL-3, PRL-R, PRL3; protein tyrosine phosphatase
type IVA, member 3 (EC:3.1.3.48); K01104 protein-tyrosine
phosphatase [EC:3.1.3.48]
Length=148
Score = 81.6 bits (200), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 50/144 (34%), Positives = 68/144 (47%), Gaps = 27/144 (18%)
Query 1 AGMVLNVPTLIESRGVKCLILDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGA 60
A M P + + ++ LI PTN L ++ L + G T +VR C TYD+ P+
Sbjct 2 ARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKD 61
Query 61 GIRVHDLTFPDGEAPPAEVIARWRAL--AAQAQAEGGVLAVHCVAGLGRGPVLVAVSLID 118
GI V D F DG PP +V+ W +L A +A G +AVHCVAGLGR
Sbjct 62 GITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGR----------- 110
Query 119 SGFEAEEAVNFIRSRRKGAINRRQ 142
+R+GAIN +Q
Sbjct 111 --------------KRRGAINSKQ 120
> dre:393148 cdc14b, MGC55844, cdc14a, zgc:55844; CDC14 cell division
cycle 14 homolog B; K06639 cell division cycle 14 [EC:3.1.3.48]
Length=404
Score = 65.9 bits (159), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 37/110 (33%), Positives = 54/110 (49%), Gaps = 4/110 (3%)
Query 30 QAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDLTFPDGEAPPAEVIARWRALAAQ 89
+AY + VT ++R YD G + HDL F DG P +++R+ +
Sbjct 151 EAYFPYFRKHNVTTIIRLNKKMYDSKRFTDVGFKHHDLFFVDGSTPNDSIVSRFLHICEN 210
Query 90 AQAEGGVLAVHCVAGLGRGPVLVAVSLIDS-GFEAEEAVNFIRSRRKGAI 138
A GV+AVHC AGLGR L+ L+ A EA+ +IR R G++
Sbjct 211 AD---GVIAVHCKAGLGRTGTLIGCYLMKHFRLTAAEAIAWIRICRPGSV 257
> dre:394124 cdc14aa, CDC14A, MGC63654, zgc:63654; CDC14 cell
division cycle 14 homolog A, a; K06639 cell division cycle 14
[EC:3.1.3.48]
Length=592
Score = 60.5 bits (145), Expect = 2e-09, Method: Composition-based stats.
Identities = 39/110 (35%), Positives = 54/110 (49%), Gaps = 4/110 (3%)
Query 30 QAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDLTFPDGEAPPAEVIARWRALAAQ 89
+AY + Q VTD+VR Y+ AG HDL F DG P + R+ +
Sbjct 208 EAYFSYFRQHNVTDVVRLNKKIYEGRRFTDAGFEHHDLFFVDGTTPSDLLTRRFLHICES 267
Query 90 AQAEGGVLAVHCVAGLGRGPVLVAVSLIDS-GFEAEEAVNFIRSRRKGAI 138
A+ G +AVHC AGLGR L+ L+ F A EA+ + R R G++
Sbjct 268 AK---GAVAVHCKAGLGRTGTLIGCYLMKHYRFTAPEAIAWTRICRPGSV 314
> dre:436735 zgc:92902; K14165 dual specificity phosphatase [EC:3.1.3.16
3.1.3.48]
Length=152
Score = 58.9 bits (141), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 37/118 (31%), Positives = 58/118 (49%), Gaps = 8/118 (6%)
Query 29 LQAYLAQLVQVGVTDLVRTC---PPTYDEGPVIGAGIRVHDLTFPDGEAPPAEVIARWRA 85
+ A+ L+ G+ LV PP +D P + +H + D AP E I R+
Sbjct 25 MTAHYQYLLNSGIKHLVTLTERKPPDHDTCP----DLTLHHIKINDFCAPTFEQINRFLT 80
Query 86 LAAQAQAEGGVLAVHCVAGLGRGPVLVAVSLIDS-GFEAEEAVNFIRSRRKGAINRRQ 142
+ +A A G +AVHC+ G GR ++A L+ S +A+N IR R+G+I R+
Sbjct 81 IVEEANASGQAVAVHCLHGFGRTGTMLACYLVKSRKISGIDAINEIRRIRRGSIETRE 138
> sce:YFR028C CDC14, OAF3; Cdc14p (EC:3.1.3.48); K06639 cell division
cycle 14 [EC:3.1.3.48]
Length=551
Score = 57.8 bits (138), Expect = 1e-08, Method: Composition-based stats.
Identities = 37/114 (32%), Positives = 53/114 (46%), Gaps = 1/114 (0%)
Query 26 NENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDLTFPDGEAPPAEVIARWRA 85
N+ ++ L V +VR Y++ GI+ DL F DG P ++ +
Sbjct 208 NQPFKSVLNFFANNNVQLVVRLNSHLYNKKHFEDIGIQHLDLIFEDGTCPDLSIVKNFVG 267
Query 86 LAAQAQAEGGVLAVHCVAGLGRGPVLVAVSLIDS-GFEAEEAVNFIRSRRKGAI 138
A GG +AVHC AGLGR L+ LI + GF A E + F+R R G +
Sbjct 268 AAETIIKRGGKIAVHCKAGLGRTGCLIGAHLIYTYGFTANECIGFLRFIRPGMV 321
> mmu:218294 Cdc14b, 2810432N10Rik, A530086E13Rik, AA472821, CDC14B3,
Cdc14B1; CDC14 cell division cycle 14 homolog B (S.
cerevisiae) (EC:3.1.3.16 3.1.3.48); K06639 cell division cycle
14 [EC:3.1.3.48]
Length=448
Score = 56.6 bits (135), Expect = 2e-08, Method: Composition-based stats.
Identities = 33/110 (30%), Positives = 51/110 (46%), Gaps = 4/110 (3%)
Query 30 QAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDLTFPDGEAPPAEVIARWRALAAQ 89
+ Y+ VT ++R YD AG HDL FPDG P ++ + +
Sbjct 209 ETYIPYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFPDGSTPAESIVQEFLDICEN 268
Query 90 AQAEGGVLAVHCVAGLGRGPVLVAVSLIDS-GFEAEEAVNFIRSRRKGAI 138
+ G +AVHC AGLGR L+ L+ A E++ ++R R G++
Sbjct 269 VK---GAIAVHCKAGLGRTGTLIGCYLMKHYRMTAAESIAWLRICRPGSV 315
> dre:565969 cdc14ab, si:dkey-168j9.1; CDC14 cell division cycle
14 homolog A, b; K06639 cell division cycle 14 [EC:3.1.3.48]
Length=510
Score = 56.6 bits (135), Expect = 3e-08, Method: Composition-based stats.
Identities = 40/110 (36%), Positives = 57/110 (51%), Gaps = 4/110 (3%)
Query 30 QAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDLTFPDGEAPPAEVIARWRALAAQ 89
+AY + VT +VR YD AG +DL F DG + P+++I R R L
Sbjct 226 EAYFPYFRKHNVTTIVRLNKKIYDAKRFTDAGFDHYDLFFVDG-STPSDIITR-RFLHI- 282
Query 90 AQAEGGVLAVHCVAGLGRGPVLVAVSLIDS-GFEAEEAVNFIRSRRKGAI 138
++ G +AVHC AGLGR L+ L+ F + EA+ +IR R G+I
Sbjct 283 CESTSGAVAVHCKAGLGRTGTLIGCYLMKHYRFTSAEAIAWIRICRPGSI 332
> hsa:8555 CDC14B, CDC14B3, Cdc14B1, Cdc14B2, hCDC14B; CDC14 cell
division cycle 14 homolog B (S. cerevisiae) (EC:3.1.3.16
3.1.3.48); K06639 cell division cycle 14 [EC:3.1.3.48]
Length=461
Score = 55.1 bits (131), Expect = 7e-08, Method: Composition-based stats.
Identities = 33/110 (30%), Positives = 51/110 (46%), Gaps = 4/110 (3%)
Query 30 QAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDLTFPDGEAPPAEVIARWRALAAQ 89
+ Y+ VT ++R YD AG HDL F DG P ++ + +
Sbjct 209 ETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDICEN 268
Query 90 AQAEGGVLAVHCVAGLGRGPVLVAVSLIDS-GFEAEEAVNFIRSRRKGAI 138
A+ G +AVHC AGLGR L+A ++ A E + ++R R G++
Sbjct 269 AE---GAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSV 315
> mmu:229776 Cdc14a, A830059A17Rik, CDC14A2, CDC14a1, Cdc14; CDC14
cell division cycle 14 homolog A (S. cerevisiae) (EC:3.1.3.16
3.1.3.48); K06639 cell division cycle 14 [EC:3.1.3.48]
Length=603
Score = 55.1 bits (131), Expect = 8e-08, Method: Composition-based stats.
Identities = 35/110 (31%), Positives = 52/110 (47%), Gaps = 4/110 (3%)
Query 30 QAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDLTFPDGEAPPAEVIARWRALAAQ 89
+AY + VT +VR Y+ AG +DL F DG P ++ R+ +
Sbjct 210 EAYFPYFKKNNVTTIVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICEN 269
Query 90 AQAEGGVLAVHCVAGLGRGPVLVAVSLIDS-GFEAEEAVNFIRSRRKGAI 138
+ G +AVHC AGLGR L+A ++ F E + +IR R G+I
Sbjct 270 TE---GAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSI 316
> hsa:8556 CDC14A, cdc14, hCDC14; CDC14 cell division cycle 14
homolog A (S. cerevisiae) (EC:3.1.3.16 3.1.3.48); K06639 cell
division cycle 14 [EC:3.1.3.48]
Length=594
Score = 54.3 bits (129), Expect = 1e-07, Method: Composition-based stats.
Identities = 35/110 (31%), Positives = 52/110 (47%), Gaps = 4/110 (3%)
Query 30 QAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDLTFPDGEAPPAEVIARWRALAAQ 89
+AY + VT +VR Y+ AG +DL F DG P ++ R+ +
Sbjct 210 EAYFPYFKKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICEN 269
Query 90 AQAEGGVLAVHCVAGLGRGPVLVAVSLIDS-GFEAEEAVNFIRSRRKGAI 138
+ G +AVHC AGLGR L+A ++ F E + +IR R G+I
Sbjct 270 TE---GAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSI 316
> xla:403393 cdc14a, xcdc14a; CDC14 cell division cycle 14 homolog
A; K06639 cell division cycle 14 [EC:3.1.3.48]
Length=576
Score = 53.9 bits (128), Expect = 1e-07, Method: Composition-based stats.
Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 4/110 (3%)
Query 30 QAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDLTFPDGEAPPAEVIARWRALAAQ 89
+AY + + ++R YD AG +DL F DG P ++ R+ L
Sbjct 208 EAYFPYFRKHNIRAVIRLNKKIYDAKRFTDAGFDHYDLFFVDGSTPSDGIVRRFLNLCEN 267
Query 90 AQAEGGVLAVHCVAGLGRGPVLVAVSLIDS-GFEAEEAVNFIRSRRKGAI 138
G +AVHC AGLGR L+A ++ F E + +IR+ R G+I
Sbjct 268 TD---GAIAVHCKAGLGRTGTLIACYIMKHYRFTHSETIAWIRTCRPGSI 314
> cpv:cgd7_4470 CDC14 phosphatase ; K06639 cell division cycle
14 [EC:3.1.3.48]
Length=453
Score = 53.9 bits (128), Expect = 2e-07, Method: Composition-based stats.
Identities = 33/108 (30%), Positives = 54/108 (50%), Gaps = 4/108 (3%)
Query 32 YLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDLTFPDGEAPPAEVIARWRALAAQAQ 91
Y+ ++ V+ ++R Y+ GI+ +L F DG PP ++ R+ L +
Sbjct 218 YIPIFKKLKVSTVIRLNKKQYESERFTNNGIKHEELFFIDGSCPPQNILNRFLELT---E 274
Query 92 AEGGVLAVHCVAGLGR-GPVLVAVSLIDSGFEAEEAVNFIRSRRKGAI 138
E GV AVHC AGLGR G +L ++ + F A + + R R G++
Sbjct 275 NEKGVFAVHCKAGLGRTGTLLGCYAIKNYRFTASAWIGWNRIARPGSV 322
> hsa:54935 DUSP23, DUSP25, FLJ20442, LDP-3, MOSP, RP11-190A12.1,
VHZ; dual specificity phosphatase 23 (EC:3.1.3.16 3.1.3.48);
K14165 dual specificity phosphatase [EC:3.1.3.16 3.1.3.48]
Length=150
Score = 52.4 bits (124), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 38/116 (32%), Positives = 55/116 (47%), Gaps = 8/116 (6%)
Query 28 NLQAYLAQLVQVGVTDLVRTC---PPTYDEGPVIGAGIRVHDLTFPDGEAPPAEVIARWR 84
L A+ L+ +GV LV PP D P G+ +H L PD P + I R+
Sbjct 23 RLPAHYQFLLDLGVRHLVSLTERGPPHSDSCP----GLTLHRLRIPDFCPPAPDQIDRFV 78
Query 85 ALAAQAQAEGGVLAVHCVAGLGRGPVLVAVSLI-DSGFEAEEAVNFIRSRRKGAIN 139
+ +A A G + VHC G GR ++A L+ + G A +A+ IR R G+I
Sbjct 79 QIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIE 134
> dre:323834 fc11c10, wu:fc11c10; si:dkeyp-95d10.1
Length=161
Score = 52.4 bits (124), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 5/123 (4%)
Query 21 LDAPTNENLQAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDLTFPDGEAPPAEVI 80
L PT + YL + L+ PP Y++ P + +H ++ D P I
Sbjct 24 LARPTMVHHYRYLLDHGIKHLVSLLEIKPPNYEKCPELS----LHQISIVDFTPPSRSQI 79
Query 81 ARWRALAAQAQAEGGVLAVHCVAGLGRGPVLVAVSLIDS-GFEAEEAVNFIRSRRKGAIN 139
++ ++ +A A+G +AVHC G GR ++A L+ S EEA+ IR R+G++
Sbjct 80 LQFLSIVEKANAKGEGVAVHCAHGHGRTGTMLACYLVKSRHLSGEEAIKEIRRLREGSVE 139
Query 140 RRQ 142
++
Sbjct 140 TKE 142
> xla:407839 cdc14b, MGC81657, cdc14beta, xcdc14b; CDC14 cell
division cycle 14 homolog B; K06639 cell division cycle 14 [EC:3.1.3.48]
Length=452
Score = 52.4 bits (124), Expect = 5e-07, Method: Composition-based stats.
Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 4/110 (3%)
Query 30 QAYLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDLTFPDGEAPPAEVIARWRALAAQ 89
+AY + +T ++R YD A HDL F DG P ++ ++ +
Sbjct 209 EAYFPYFRKHHLTTIIRLNKKMYDANRFTDADFEHHDLFFVDGSTPSDAIVKKFLNICEN 268
Query 90 AQAEGGVLAVHCVAGLGRGPVLVAVSLIDS-GFEAEEAVNFIRSRRKGAI 138
A G +AVHC AGLGR L+ ++ A E + +IR R G++
Sbjct 269 AD---GAIAVHCKAGLGRTGTLIGCYMMKHYRMTAAETIAWIRICRPGSV 315
> xla:495348 dusp23; dual specificity phosphatase 23; K14165 dual
specificity phosphatase [EC:3.1.3.16 3.1.3.48]
Length=151
Score = 52.0 bits (123), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 34/118 (28%), Positives = 56/118 (47%), Gaps = 8/118 (6%)
Query 29 LQAYLAQLVQVGVTDLVRTC---PPTYDEGPVIGAGIRVHDLTFPDGEAPPAEVIARWRA 85
L A+ L + G+ L+ PP +D P GI +H + D AP E I +
Sbjct 25 LPAHYEYLYENGIRHLITLTEHKPPYHDTCP----GITLHRIRIQDFCAPSLEQIKNFLK 80
Query 86 LAAQAQAEGGVLAVHCVAGLGRGPVLVAVSLID-SGFEAEEAVNFIRSRRKGAINRRQ 142
+ A+++G + VHC+ G GR ++A L+ +A+N IR R+G+I +
Sbjct 81 IVDDAKSKGEAVGVHCLHGFGRTGTMLACYLVKVRKITGVDAINEIRCLRRGSIETNE 138
> cel:C17G10.4 cdc-14; Cell Division Cycle related family member
(cdc-14); K06639 cell division cycle 14 [EC:3.1.3.48]
Length=1063
Score = 52.0 bits (123), Expect = 7e-07, Method: Composition-based stats.
Identities = 34/99 (34%), Positives = 51/99 (51%), Gaps = 4/99 (4%)
Query 41 VTDLVRTCPPTYDEGPVIGAGIRVHDLTFPDGEAPPAEVIARWRALAAQAQAEGGVLAVH 100
V+ +VR YD AG DL F DG P E++ ++ + +GGV AVH
Sbjct 238 VSTIVRLNAKNYDASKFTKAGFDHVDLFFIDGSTPSDEIMLKF--IKVVDNTKGGV-AVH 294
Query 101 CVAGLGRGPVLVAVSLI-DSGFEAEEAVNFIRSRRKGAI 138
C AGLGR L+A ++ + G A E + ++R R G++
Sbjct 295 CKAGLGRTGTLIACWMMKEYGLTAGECMGWLRVCRPGSV 333
> mmu:68440 Dusp23, 1300005N15Rik, LDP-3, MGC73633; dual specificity
phosphatase 23 (EC:3.1.3.16 3.1.3.48)
Length=150
Score = 48.5 bits (114), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 36/116 (31%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
Query 28 NLQAYLAQLVQVGVTDLVRTC---PPTYDEGPVIGAGIRVHDLTFPDGEAPPAEVIARWR 84
L A+ L+ GV LV PP D P G+ +H + PD P E I ++
Sbjct 23 RLPAHYQFLLDQGVRHLVSLTERGPPHSDSCP----GLTLHRMRIPDFCPPSPEQIDQFV 78
Query 85 ALAAQAQAEGGVLAVHCVAGLGRGPVLVAVSLI-DSGFEAEEAVNFIRSRRKGAIN 139
+ +A A G + VHC G GR ++A L+ + A +A+ IR R G+I
Sbjct 79 KIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERALAAGDAIAEIRRLRPGSIE 134
> dre:565773 ptpdc1, zgc:158271; protein tyrosine phosphatase
domain containing 1 (EC:3.1.3.-)
Length=713
Score = 45.4 bits (106), Expect = 6e-05, Method: Composition-based stats.
Identities = 31/93 (33%), Positives = 50/93 (53%), Gaps = 4/93 (4%)
Query 51 TYDEGPVIGAGIRVHDLTFPD-GEAPPAEVIARWRALAAQAQAEGGVLAVHCVAGLGRGP 109
TY + AGI ++ + D G A ++ + ++ Q G +AVHC AGLGR
Sbjct 139 TYRPELFMEAGIYFYNFGWKDYGVASLTTILDMVKVMSFAMQE--GKIAVHCHAGLGRTG 196
Query 110 VLVAVSLI-DSGFEAEEAVNFIRSRRKGAINRR 141
VL+A L+ S A++A+ F+R++R +I R
Sbjct 197 VLIACFLVFTSRMSADQAILFVRAKRPNSIQTR 229
> tgo:TGME49_114430 dual specificity protein phosphatase CDC14A,
putative (EC:3.1.3.16); K06639 cell division cycle 14 [EC:3.1.3.48]
Length=479
Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats.
Identities = 33/101 (32%), Positives = 45/101 (44%), Gaps = 4/101 (3%)
Query 39 VGVTDLVRTCPPTYDEGPVIGAGIRVHDLTFPDGEAPPAEVIARWRALAAQAQAEGGVLA 98
+G+ +VR YD I DL F DG P E+I +A + +A
Sbjct 226 LGIKTVVRLNKKQYDARKFTDRNIEHVDLFFVDGTCPSREII---QAFLQVVENRDHPIA 282
Query 99 VHCVAGLGRGPVLVAVSLIDS-GFEAEEAVNFIRSRRKGAI 138
VHC AGLGR L+ I + F A E + + R R G+I
Sbjct 283 VHCKAGLGRTGTLIGCYAIKNFKFPAVEWIGWNRLCRPGSI 323
> mmu:218232 Ptpdc1, AI843923, AW456874, Naa-1; protein tyrosine
phosphatase domain containing 1 (EC:3.1.3.48); K01104 protein-tyrosine
phosphatase [EC:3.1.3.48]
Length=747
Score = 42.7 bits (99), Expect = 3e-04, Method: Composition-based stats.
Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 20/142 (14%)
Query 19 LILDAPTNENLQAY--LAQLVQVGVTDLVRTCPP----------------TYDEGPVIGA 60
L + P++E L+ Y + Q + G+ ++ P TY + A
Sbjct 91 LAMARPSSELLEKYRIIEQFLGQGIKTIINLQRPGEHASCGSALEQESGFTYLPEAFMEA 150
Query 61 GIRVHDLTFPDGEAPPAEVIARWRALAAQAQAEGGVLAVHCVAGLGRGPVLVAVSLI-DS 119
GI ++ + D I + A EG V AVHC AGLGR VL+A L+ +
Sbjct 151 GIYFYNFGWKDYGVASLTAILDMVKVMTFALQEGKV-AVHCHAGLGRTGVLIACYLVFAT 209
Query 120 GFEAEEAVNFIRSRRKGAINRR 141
A++A+ F+R++R +I R
Sbjct 210 RMTADQAIIFVRAKRPNSIQTR 231
> hsa:138639 PTPDC1, FLJ42922, PTP9Q22; protein tyrosine phosphatase
domain containing 1 (EC:3.1.3.48); K01104 protein-tyrosine
phosphatase [EC:3.1.3.48]
Length=806
Score = 42.4 bits (98), Expect = 5e-04, Method: Composition-based stats.
Identities = 38/142 (26%), Positives = 63/142 (44%), Gaps = 20/142 (14%)
Query 19 LILDAPTNENLQAY--LAQLVQVGVTDLVRTCPP----------------TYDEGPVIGA 60
L + P++E L+ Y + Q + G+ ++ P TY + A
Sbjct 143 LAMARPSSELLEKYHIIDQFLSHGIKTIINLQRPGEHASCGNPLEQESGFTYLPEAFMEA 202
Query 61 GIRVHDLTFPDGEAPPAEVIARWRALAAQAQAEGGVLAVHCVAGLGRGPVLVAVSLI-DS 119
GI ++ + D I + A EG V A+HC AGLGR VL+A L+ +
Sbjct 203 GIYFYNFGWKDYGVASLTTILDMVKVMTFALQEGKV-AIHCHAGLGRTGVLIACYLVFAT 261
Query 120 GFEAEEAVNFIRSRRKGAINRR 141
A++A+ F+R++R +I R
Sbjct 262 RMTADQAIIFVRAKRPNSIQTR 283
> dre:570928 si:ch73-142c19.2
Length=658
Score = 42.4 bits (98), Expect = 5e-04, Method: Composition-based stats.
Identities = 37/143 (25%), Positives = 67/143 (46%), Gaps = 22/143 (15%)
Query 19 LILDAPTNENLQAY--LAQLVQVGVTDLVR-TCPP---------------TYDEGPVIGA 60
L + P+ E ++ + + Q ++ G+ ++ CP TY + A
Sbjct 68 LAMARPSTETIEKFNIIDQFLRCGLKTIINLQCPGEHASCGNPLDPDSGFTYRPETFMEA 127
Query 61 GIRVHDLTFPD-GEAPPAEVIARWRALAAQAQAEGGVLAVHCVAGLGRGPVLVAVSLI-D 118
GI ++ + D G A ++ + ++ Q G +AVHC AGLGR VL+A L+
Sbjct 128 GIYFYNFRWIDYGVASLTSILDMVKVMSFAIQE--GKMAVHCHAGLGRTGVLLACYLLFT 185
Query 119 SGFEAEEAVNFIRSRRKGAINRR 141
+ A++A+ IR++R +I R
Sbjct 186 TQMTADQAILLIRNKRPNSIQTR 208
> ath:AT5G39400 PTEN1; PTEN1; phosphatase; K01110 phosphatidylinositol-3,4,5-trisphosphate
3-phosphatase [EC:3.1.3.67]
Length=412
Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 15/96 (15%)
Query 51 TYDEGPVIGAGIRVHDLTFPDGEAPP-------AEVIARWRALAAQAQAEGGVLAVHCVA 103
+YD G RV F D P E + W +L + + VHC+A
Sbjct 103 SYDPDNFYG---RVERFPFDDNHVPSLKMIQLFCESVHSWLSLDPK-----NIAVVHCMA 154
Query 104 GLGRGPVLVAVSLIDSGFEAEEAVNFIRSRRKGAIN 139
G GR ++V+ L+ G AEEA+ SRR N
Sbjct 155 GKGRTGLMVSAYLVYGGMSAEEALEMYASRRTTNNN 190
> dre:393862 MGC77752; zgc:77752
Length=464
Score = 40.8 bits (94), Expect = 0.001, Method: Composition-based stats.
Identities = 22/48 (45%), Positives = 31/48 (64%), Gaps = 1/48 (2%)
Query 95 GVLAVHCVAGLGRGPVLVAVSLIDS-GFEAEEAVNFIRSRRKGAINRR 141
G +AVHC AGLGR VL+A L+ + A EAV+++R +R +I R
Sbjct 159 GKVAVHCHAGLGRTGVLIACYLVYTCRISASEAVHYVRIKRPRSIQTR 206
> hsa:5728 PTEN, 10q23del, BZS, DEC, GLM2, MGC11227, MHAM, MMAC1,
PTEN1, TEP1; phosphatase and tensin homolog (EC:3.1.3.67
3.1.3.16 3.1.3.48); K01110 phosphatidylinositol-3,4,5-trisphosphate
3-phosphatase [EC:3.1.3.67]
Length=403
Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 26/85 (30%), Positives = 42/85 (49%), Gaps = 7/85 (8%)
Query 61 GIRVHDLTFPDGEAPPAEVIARWRALAAQ--AQAEGGVLAVHCVAGLGRGPVLVAVSLID 118
RV F D P E+I + Q ++ + V A+HC AG GR V++ L+
Sbjct 82 NCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLH 141
Query 119 SG--FEAEEAVNF---IRSRRKGAI 138
G +A+EA++F +R+R K +
Sbjct 142 RGKFLKAQEALDFYGEVRTRDKKGV 166
> mmu:19211 Pten, 2310035O07Rik, A130070J02Rik, AI463227, B430203M17Rik,
MGC183880, MMAC1, TEP1; phosphatase and tensin homolog
(EC:3.1.3.67 3.1.3.16 3.1.3.48); K01110 phosphatidylinositol-3,4,5-trisphosphate
3-phosphatase [EC:3.1.3.67]
Length=403
Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 26/85 (30%), Positives = 42/85 (49%), Gaps = 7/85 (8%)
Query 61 GIRVHDLTFPDGEAPPAEVIARWRALAAQ--AQAEGGVLAVHCVAGLGRGPVLVAVSLID 118
RV F D P E+I + Q ++ + V A+HC AG GR V++ L+
Sbjct 82 NCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLH 141
Query 119 SG--FEAEEAVNF---IRSRRKGAI 138
G +A+EA++F +R+R K +
Sbjct 142 RGKFLKAQEALDFYGEVRTRDKKGV 166
> xla:444752 dusp5, MGC84792; dual specificity phosphatase 5;
K04459 dual specificity phosphatase [EC:3.1.3.16 3.1.3.48]
Length=373
Score = 38.5 bits (88), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 5/104 (4%)
Query 32 YLAQLVQVGVTDLVRTCPPTYDEGPVIGAGIRVHDLTFPDGEAPPAEVIARWRALAAQAQ 91
+LA L + ++ R P + + I V D D + E I +
Sbjct 190 FLANLHITALLNVSRKSSPDFCKEQYSYKWIPVEDNHTADISSHFQEAID----FIDSVK 245
Query 92 AEGGVLAVHCVAGLGRGPVLVAVSLIDS-GFEAEEAVNFIRSRR 134
GG + VHC AG+ R P + L+ + F EEA +I+ RR
Sbjct 246 RAGGRVLVHCEAGISRSPTICMAYLMKTRKFHLEEAFEYIKQRR 289
Lambda K H
0.320 0.138 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 2683748972
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
Posted date: Sep 16, 2011 8:45 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40